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Wyświetlanie 1-20 z 402408
Tytuł:
JNK regulates the Nrf2/NQO1-ARE pathway against Microcystins-Induced oxidative stress in freshwater mussel Cristaria plicata.
Autorzy:
Wu J; Jiangxi Science and Technology Normal University, Nanchang 330013, China. Electronic address: .
Lv R; College of Life Science, Nanchang University, Nanchang 330031, China.
Qiu L; Jiangxi Science and Technology Normal University, Nanchang 330013, China.
Zhang S; Jiangxi Science and Technology Normal University, Nanchang 330013, China.
Jiao H; Jiangxi Science and Technology Normal University, Nanchang 330013, China.
Wang Y; Jiangxi Science and Technology Normal University, Nanchang 330013, China.
Luo S; Jiangxi Science and Technology Normal University, Nanchang 330013, China.
Fang H; Jiangxi Science and Technology Normal University, Nanchang 330013, China.
Wen C; College of Life Science, Nanchang University, Nanchang 330031, China. Electronic address: .
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Źródło:
Gene [Gene] 2023 Oct 20; Vol. 883, pp. 147653. Date of Electronic Publication: 2023 Jul 20.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidant Response Elements*
Unionidae*/genetics
Animals ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; Kelch-Like ECH-Associated Protein 1/genetics ; Microcystins/toxicity ; Microcystins/genetics ; Oxidative Stress ; Mitogen-Activated Protein Kinases/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
An antioxidant response element regulates the HIF1α axis in breast cancer cells.
Autorzy:
Lacher SE; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth, MN, 55812, USA. Electronic address: .
Skon-Hegg C; Whiteside Institute for Clinical Research, St. Luke's Hospital, University of Minnesota Medical School, Duluth, MN, 55812, USA.
Ruis BL; Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, MN, 55455, USA.
Krznarich J; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth, MN, 55812, USA.
Slattery M; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth, MN, 55812, USA. Electronic address: .
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Źródło:
Free radical biology & medicine [Free Radic Biol Med] 2023 Aug 01; Vol. 204, pp. 243-251. Date of Electronic Publication: 2023 May 11.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antioxidant Response Elements*
Hypoxia-Inducible Factor 1, alpha Subunit*/genetics
Gene Expression Regulation, Neoplastic*
Humans ; Cell Line, Tumor ; Mutation ; NF-E2-Related Factor 2/metabolism ; Cyclin-Dependent Kinase Inhibitor p21/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Optimization of 3-aminotetrahydrothiophene 1,1-dioxides with improved potency and efficacy as non-electrophilic antioxidant response element (ARE) activators.
Autorzy:
Jo J; College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea.
Kim J; College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea.
Ibrahim L; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, United States; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, United States.
Kumar M; California Institute for Biomedical Research, La Jolla, CA 92037, United States.
Iaconelli J; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, United States.
Tran CS; College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea.
Moon HR; College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea; Research Institute for Drug Development, Pusan National University, Busan 46241, Republic of Korea.
Jung Y; College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea; Research Institute for Drug Development, Pusan National University, Busan 46241, Republic of Korea.
Wiseman RL; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, United States.
Lairson LL; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, United States.
Chatterjee AK; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, United States.
Bollong MJ; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, United States. Electronic address: .
Yun H; College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea; Research Institute for Drug Development, Pusan National University, Busan 46241, Republic of Korea. Electronic address: .
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Źródło:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2023 Jun 01; Vol. 89, pp. 129306. Date of Electronic Publication: 2023 Apr 26.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antioxidants*/pharmacology
Antioxidant Response Elements*
NF-E2-Related Factor 2/metabolism ; Oxidative Stress
Czasopismo naukowe
Szczegóły
Tytuł:
The Contribution of the Nrf2/ARE System to Mechanotransduction in Musculoskeletal and Periodontal Tissues.
Autorzy:
Fragoulis A; Department of Anatomy and Cell Anatomy, Uniklinik RWTH Aachen, RWTH Aachen University, 52074 Aachen, Germany.
Tohidnezhad M; Department of Anatomy and Cell Anatomy, Uniklinik RWTH Aachen, RWTH Aachen University, 52074 Aachen, Germany.
Kubo Y; Department of Anatomy and Cell Anatomy, Uniklinik RWTH Aachen, RWTH Aachen University, 52074 Aachen, Germany.
Wruck CJ; Department of Anatomy and Cell Anatomy, Uniklinik RWTH Aachen, RWTH Aachen University, 52074 Aachen, Germany.
Craveiro RB; Department of Orthodontics, Dental Clinic, Uniklinik RWTH Aachen, RWTH Aachen University, 52074 Aachen, Germany.
Bock A; Department of Oral and Maxillofacial Surgery, Uniklinik RWTH Aachen, RWTH Aachen University, 52074 Aachen, Germany.
Wolf M; Department of Orthodontics, Dental Clinic, Uniklinik RWTH Aachen, RWTH Aachen University, 52074 Aachen, Germany.
Pufe T; Department of Anatomy and Cell Anatomy, Uniklinik RWTH Aachen, RWTH Aachen University, 52074 Aachen, Germany.
Jahr H; Department of Anatomy and Cell Anatomy, Uniklinik RWTH Aachen, RWTH Aachen University, 52074 Aachen, Germany.; Institute of Structural Mechanics and Lightweight Design, RWTH Aachen University, 52062 Aachen, Germany.
Suhr F; Division of Molecular Exercise Physiology, Faculty of Life Sciences: Food, Nutrition and Health, University of Bayreuth, 95326 Kulmbach, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 23; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 23.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antioxidant Response Elements*
NF-E2-Related Factor 2*/metabolism
Humans ; Kelch-Like ECH-Associated Protein 1/metabolism ; Mechanotransduction, Cellular ; Oxidants ; Oxidative Stress ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Natural products targeting Nrf2/ARE signaling pathway in the treatment of inflammatory bowel disease.
Autorzy:
Li B; Provincial-level Key Laboratory for Molecular Medicine of Major Diseases and The Prevention and Treatment with Traditional Chinese Medicine Research in Gansu Colleges and University, Gansu University of Chinese Medicine, Lanzhou 730000, China; College of Basic Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Wang Y; College of Public Health, Gansu University of Chinese Medicine, Lanzhou 730000, China; Key Laboratory for Transfer of Dunhuang Medicine at the Provincial and Ministerial Level, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Jiang X; Provincial-level Key Laboratory for Molecular Medicine of Major Diseases and The Prevention and Treatment with Traditional Chinese Medicine Research in Gansu Colleges and University, Gansu University of Chinese Medicine, Lanzhou 730000, China; College of Basic Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Du H; Gansu University of Political Science and Law, Lanzhou 730000, China.
Shi Y; Provincial-level Key Laboratory for Molecular Medicine of Major Diseases and The Prevention and Treatment with Traditional Chinese Medicine Research in Gansu Colleges and University, Gansu University of Chinese Medicine, Lanzhou 730000, China; College of Basic Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Xiu M; College of Public Health, Gansu University of Chinese Medicine, Lanzhou 730000, China; Key Laboratory for Transfer of Dunhuang Medicine at the Provincial and Ministerial Level, Gansu University of Chinese Medicine, Lanzhou 730000, China. Electronic address: .
Liu Y; Provincial-level Key Laboratory for Molecular Medicine of Major Diseases and The Prevention and Treatment with Traditional Chinese Medicine Research in Gansu Colleges and University, Gansu University of Chinese Medicine, Lanzhou 730000, China; Key Laboratory for Transfer of Dunhuang Medicine at the Provincial and Ministerial Level, Gansu University of Chinese Medicine, Lanzhou 730000, China. Electronic address: .
He J; Provincial-level Key Laboratory for Molecular Medicine of Major Diseases and The Prevention and Treatment with Traditional Chinese Medicine Research in Gansu Colleges and University, Gansu University of Chinese Medicine, Lanzhou 730000, China; College of Basic Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, China; Key Laboratory for Transfer of Dunhuang Medicine at the Provincial and Ministerial Level, Gansu University of Chinese Medicine, Lanzhou 730000, China. Electronic address: .
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Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Aug; Vol. 164, pp. 114950. Date of Electronic Publication: 2023 May 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Biological Products*/pharmacology
Biological Products*/therapeutic use
Inflammatory Bowel Diseases*/drug therapy
Inflammatory Bowel Diseases*/metabolism
Colitis, Ulcerative*
Humans ; NF-E2-Related Factor 2/metabolism ; Antioxidant Response Elements ; Signal Transduction/physiology
Czasopismo naukowe
Szczegóły
Tytuł:
Phytochemical Analysis and Evaluation of the Antioxidant, Antiproliferative, Antibacterial, and Antibiofilm Effects of Globularia alypum (L.) Leaves.
Autorzy:
Nouir, Sahar (AUTHOR)
Dbeibia, Amal (AUTHOR)
Bouhajeb, Rim (AUTHOR)
Haddad, Houda (AUTHOR)
Khélifa, Amani (AUTHOR)
Achour, Lotfi (AUTHOR)
Ghardallou, Mariem (AUTHOR)
Zaïri, Amira (AUTHOR)
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Źródło:
Molecules. May2023, Vol. 28 Issue 10, p4019. 15p.
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
ADSC-Exosomes Alleviate MTX-induced Rat Neuronal Damage by Activating Nrf2-ARE Pathway.
Autorzy:
Huang T; The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Tong H; The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Zhou H; The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Wang J; The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Hu L; The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Wang Y; The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Huang Z; The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. .
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Źródło:
Journal of molecular neuroscience : MN [J Mol Neurosci] 2022 Jun; Vol. 72 (6), pp. 1334-1344. Date of Electronic Publication: 2022 Mar 23.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidant Response Elements*
Exosomes*/drug effects
Exosomes*/metabolism
Mesenchymal Stem Cells*/drug effects
Mesenchymal Stem Cells*/metabolism
NF-E2-Related Factor 2*/genetics
NF-E2-Related Factor 2*/metabolism
Neurons*/drug effects
Neurons*/metabolism
Oxidative Stress*
Animals ; Hydrogen Peroxide/metabolism ; Methotrexate/toxicity ; Rats
Czasopismo naukowe
Szczegóły
Tytuł:
Upregulation of FAM129B protects cardiomyocytes from hypoxia/reoxygenation-induced injury by inhibiting apoptosis, oxidative stress, and inflammatory response via enhancing Nrf2/ARE activation.
Autorzy:
Zeng G; Department of Cardiology, The Second Affiliated Hospital of Xi'an Jiaotong University, Shaanxi, China.; Section 2, Department of Cardiology, Xi'an International Medical Center Hospital, Shaanxi, China.
Lian C; Section 2, Department of Cardiology, Xi'an International Medical Center Hospital, Shaanxi, China.
Li W; Section 2, Department of Cardiology, Xi'an International Medical Center Hospital, Shaanxi, China.
An H; Section 2, Department of Cardiology, Xi'an International Medical Center Hospital, Shaanxi, China.
Han Y; Section 2, Department of Cardiology, Xi'an International Medical Center Hospital, Shaanxi, China.
Fang D; Section 2, Department of Cardiology, Xi'an International Medical Center Hospital, Shaanxi, China.
Zheng Q; Department of Cardiology, The Second Affiliated Hospital of Xi'an Jiaotong University, Shaanxi, China.
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Źródło:
Environmental toxicology [Environ Toxicol] 2022 May; Vol. 37 (5), pp. 1018-1031. Date of Electronic Publication: 2022 Jan 07.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidant Response Elements*
NF-E2-Related Factor 2*/metabolism
Apoptosis ; Humans ; Hypoxia/metabolism ; Myocytes, Cardiac/metabolism ; Oxidative Stress ; Up-Regulation
Czasopismo naukowe
Szczegóły
Tytuł:
FGFR2 modulates the Akt/Nrf2/ARE signaling pathway to improve angiotensin II-induced hypertension-related endothelial dysfunction.
Autorzy:
Jiao K; Division 1, Department of Cardiology, Ordos Central Hospital, Inner Mongolia, China.
Su P; Division 1, Department of Cardiology, Ordos Central Hospital, Inner Mongolia, China.
Li Y; Division 1, Department of Cardiology, Ordos Central Hospital, Inner Mongolia, China.
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Źródło:
Clinical and experimental hypertension (New York, N.Y. : 1993) [Clin Exp Hypertens] 2023 Dec 31; Vol. 45 (1), pp. 2208777.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins c-akt*/metabolism
Hypertension*/chemically induced
Hypertension*/metabolism
Humans ; NF-E2-Related Factor 2/genetics ; Angiotensin II/pharmacology ; Antioxidant Response Elements ; Signal Transduction ; Oxidative Stress ; Human Umbilical Vein Endothelial Cells ; Reactive Oxygen Species/metabolism ; Apoptosis ; Nitric Oxide Synthase Type III/metabolism ; Receptor, Fibroblast Growth Factor, Type 2/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Morphine-induced modulation of Nrf2-antioxidant response element signaling pathway in primary human brain microvascular endothelial cells.
Autorzy:
Reymond S; Department of Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Swiss Center for Applied Human Toxicology, Geneva, Switzerland.
Vujić T; Department of Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Swiss Center for Applied Human Toxicology, Geneva, Switzerland.
Schvartz D; Department of Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Swiss Center for Applied Human Toxicology, Geneva, Switzerland.
Sanchez JC; Department of Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland. .; Swiss Center for Applied Human Toxicology, Geneva, Switzerland. .
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Źródło:
Scientific reports [Sci Rep] 2022 Mar 17; Vol. 12 (1), pp. 4588. Date of Electronic Publication: 2022 Mar 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antioxidant Response Elements*
NF-E2-Related Factor 2*/metabolism
Humans ; Antioxidants/metabolism ; Antioxidants/pharmacology ; Brain/metabolism ; Endothelial Cells/metabolism ; Morphine/pharmacology ; Oxidative Stress/physiology ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genistein and Procyanidin B2 Reduce Carcinogen-Induced Reactive Oxygen Species and DNA Damage through the Activation of Nrf2/ARE Cell Signaling in Bronchial Epithelial Cells In Vitro.
Autorzy:
Suraweera TL; Department of Plant, Food, and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, NS B2N 2R8, Canada.
Merlin JPJ; Department of Plant, Food, and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, NS B2N 2R8, Canada.
Dellaire G; Department of Pathology, Faculty of Medicine, Dalhousie University, Halifax, NS B3H 4H7, Canada.
Xu Z; Department of Pathology, Faculty of Medicine, Dalhousie University, Halifax, NS B3H 4H7, Canada.; QEII Health Sciences Centre, Division of Anatomical Pathology and Cytopathology, Nova Scotia Health Authority, Halifax, NS B3H 1V8, Canada.
Rupasinghe HPV; Department of Plant, Food, and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, NS B2N 2R8, Canada.; Department of Pathology, Faculty of Medicine, Dalhousie University, Halifax, NS B3H 4H7, Canada.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 12; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 12.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinogens*/pharmacology
Epithelial Cells*/drug effects
Epithelial Cells*/metabolism
Genistein*/pharmacology
Proto-Oncogene Proteins c-akt*/metabolism
Reactive Oxygen Species*/metabolism
Proanthocyanidins*/pharmacology
Humans ; Antioxidant Response Elements/drug effects ; DNA Damage/drug effects ; Flavonoids/pharmacology ; NF-E2-Related Factor 2/metabolism ; Oxidative Stress ; Quercetin/pharmacology ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 402408

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