Temat: "antioxidant" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Protective Effect of Chitosan Oligosaccharide against Hydrogen Peroxide-Mediated Oxidative Damage and Cell Apoptosis via Activating Nrf2/ARE Signaling Pathway.
Autorzy:: Zhang X; Beijing Key Laboratory of Bioactive Substances and Functional Food, Beijing Union University, Beijing, 100191, China.
Liang S; Beijing Key Laboratory of Bioactive Substances and Functional Food, Beijing Union University, Beijing, 100191, China.
Gao X; Beijing Key Laboratory of Bioactive Substances and Functional Food, Beijing Union University, Beijing, 100191, China.
Huang H; Beijing Key Laboratory of Bioactive Substances and Functional Food, Beijing Union University, Beijing, 100191, China.
Lao F; Beijing Key Laboratory of Bioactive Substances and Functional Food, Beijing Union University, Beijing, 100191, China.
Dai X; Beijing Key Laboratory of Bioactive Substances and Functional Food, Beijing Union University, Beijing, 100191, China. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2021 Dec; Vol. 39 (6), pp. 1708-1720. Date of Electronic Publication: 2021 Oct 08.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidant Response Elements*
Apoptosis/*drug effects
Chitosan/*pharmacology
Hydrogen Peroxide/*metabolism
NF-E2-Related Factor 2/*metabolism
Oligosaccharides/*pharmacokinetics
Oxidative Stress/*drug effects
Signal Transduction/*drug effects
Blotting, Western ; Cell Line, Tumor ; Humans ; Reactive Oxygen Species ; Real-Time Polymerase Chain Reaction

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Skocz do pozycji: 2.

Tytuł:: S-Allylcysteine Protects Against Excitotoxic Damage in Rat Cortical Slices Via Reduction of Oxidative Damage, Activation of Nrf2/ARE Binding, and BDNF Preservation.
Autorzy:: Reyes-Soto CY; Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología y Neurocirugía, Insurgentes Sur 3877, 14269, Mexico City, Mexico.
Rangel-López E; Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología y Neurocirugía, Insurgentes Sur 3877, 14269, Mexico City, Mexico.
Galván-Arzate S; Departamento de Neuroquímica, Instituto Nacional de Neurología y Neurocirugía, 14269, Mexico City, Mexico.
Colín-González AL; Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología y Neurocirugía, Insurgentes Sur 3877, 14269, Mexico City, Mexico.
Silva-Palacios A; Departamento de Biomedicina Cardiovascular, Instituto Nacional de Cardiología Ignacio Chávez, 14080, Mexico City, Mexico.
Zazueta C; Departamento de Biomedicina Cardiovascular, Instituto Nacional de Cardiología Ignacio Chávez, 14080, Mexico City, Mexico.
Pedraza-Chaverri J; Facultad de Química, Departamento de Biología, Universidad Nacional Autónoma de México, 04510, Mexico City, Mexico.
Ramírez J; Unidad de Investigación en Medicina Experimental, Facultad de Medicina, Universidad Nacional Autónoma de México, 04510, Mexico City, Mexico.
Chavarria A; Unidad de Investigación en Medicina Experimental, Facultad de Medicina, Universidad Nacional Autónoma de México, 04510, Mexico City, Mexico.
Túnez I; Departamento de Bioquímica y Biología Molecular, Facultad de Medicina y Enfermería, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Universidad de Córdoba, 14004, Córdoba, Spain.
Ke T; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, 11354, USA.
Aschner M; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, 11354, USA.
Santamaría A; Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología y Neurocirugía, Insurgentes Sur 3877, 14269, Mexico City, Mexico. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2020 Dec; Vol. 38 (4), pp. 929-940. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidant Response Elements/*drug effects
Brain-Derived Neurotrophic Factor/*metabolism
Cerebral Cortex/*metabolism
Cysteine/*analogs & derivatives
NF-E2-Related Factor 2/*metabolism
Oxidative Stress/*drug effects
Animals ; Antioxidant Response Elements/physiology ; Cerebral Cortex/drug effects ; Cysteine/pharmacology ; Lipid Peroxidation/drug effects ; Lipid Peroxidation/physiology ; Male ; Neuroprotective Agents/pharmacology ; Organ Culture Techniques ; Oxidative Stress/physiology ; Protein Binding/physiology ; Rats ; Rats, Wistar

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Skocz do pozycji: 3.

Tytuł:: Vitexin protects melanocytes from oxidative stress via activating MAPK-Nrf2/ARE pathway.
Autorzy:: Li XS; Department of Dermatology, the Second Affiliated Hospital, Hunan University of Chinese Medicine, Changsha, P. R. China.
Tang XY; Department of Dermatology, the Second Affiliated Hospital, Hunan University of Chinese Medicine, Changsha, P. R. China.
Su W; Department of Dermatology, the Second Affiliated Hospital, Hunan University of Chinese Medicine, Changsha, P. R. China.
Li X; Hunan Provincal Key Laboratory of Diagnostic in Chinese Medicine, Hunan University of Chinese Medicine, Changsha, P. R. China.; Pokaż więcej
Źródło:: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2020 Dec; Vol. 42 (6), pp. 594-603. Date of Electronic Publication: 2020 Nov 03.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidant Response Elements*
Antioxidants/*pharmacology
Apigenin/*pharmacology
Melanocytes/*drug effects
Mitogen-Activated Protein Kinases/*metabolism
NF-E2-Related Factor 2/*metabolism
Oxidative Stress/*drug effects
Vitiligo/*drug therapy
Apoptosis/drug effects ; Cell Line ; Cytokines/genetics ; Cytokines/metabolism ; Humans ; Hydrogen Peroxide/toxicity ; Inflammation Mediators/metabolism ; Melanocytes/enzymology ; Melanocytes/pathology ; NF-E2-Related Factor 2/genetics ; Reactive Oxygen Species/metabolism ; Signal Transduction ; Vitiligo/enzymology ; Vitiligo/pathology

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Skocz do pozycji: 4.

Tytuł:: Astragaloside IV Protects Against Oxidative Stress in Calf Small Intestine Epithelial Cells via NFE2L2-Antioxidant Response Element Signaling.
Autorzy:: Wang Y; Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Sangyuan Road, Number 8, Jinan 250100, China.; Shandong Key Laboratory of Animal Disease Control and Breeding, Sangyuan Road, Number 8, Jinan 250100, China.; College of Life Sciences, Shandong Normal University, East Wenhua Road Number 88, Jinan 250014, China.
Jiang F; Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Sangyuan Road, Number 8, Jinan 250100, China.; Shandong Key Laboratory of Animal Disease Control and Breeding, Sangyuan Road, Number 8, Jinan 250100, China.
Cheng H; Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Sangyuan Road, Number 8, Jinan 250100, China.; Shandong Key Laboratory of Animal Disease Control and Breeding, Sangyuan Road, Number 8, Jinan 250100, China.
Tan X; Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Sangyuan Road, Number 8, Jinan 250100, China.; Shandong Key Laboratory of Animal Disease Control and Breeding, Sangyuan Road, Number 8, Jinan 250100, China.
Liu Y; Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Sangyuan Road, Number 8, Jinan 250100, China.; Shandong Key Laboratory of Animal Disease Control and Breeding, Sangyuan Road, Number 8, Jinan 250100, China.
Wei C; Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Sangyuan Road, Number 8, Jinan 250100, China.; Shandong Key Laboratory of Animal Disease Control and Breeding, Sangyuan Road, Number 8, Jinan 250100, China.
Song E; Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Sangyuan Road, Number 8, Jinan 250100, China.; Shandong Key Laboratory of Animal Disease Control and Breeding, Sangyuan Road, Number 8, Jinan 250100, China.; College of Life Sciences, Shandong Normal University, East Wenhua Road Number 88, Jinan 250014, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2019 Dec 05; Vol. 20 (24). Date of Electronic Publication: 2019 Dec 05.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidant Response Elements*
Epithelial Cells/*metabolism
Intestine, Small/*metabolism
NF-E2-Related Factor 2/*metabolism
Oxidative Stress/*drug effects
Saponins/*pharmacology
Signal Transduction/*drug effects
Triterpenes/*pharmacology
Animals ; Cattle ; Hydrogen Peroxide/metabolism

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Skocz do pozycji: 5.

Tytuł:: Catalpol Protects ARPE-19 Cells against Oxidative Stress via Activation of the Keap1/Nrf2/ARE Pathway.
Autorzy:: You L; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.
Peng H; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.
Liu J; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.
Cai M; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.
Wu H; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.
Zhang Z; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.
Bai J; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.
Yao Y; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.
Dong X; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.
Yin X; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.
Ni J; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Oct 02; Vol. 10 (10). Date of Electronic Publication: 2021 Oct 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Neuroprotection*/drug effects
Oxidative Stress*/drug effects
Oxidative Stress*/genetics
Antioxidant Response Elements/*genetics
Iridoid Glucosides/*pharmacology
Kelch-Like ECH-Associated Protein 1/*metabolism
NF-E2-Related Factor 2/*metabolism
Apoptosis/drug effects ; Cell Cycle Checkpoints/drug effects ; Cell Line ; Humans ; Hydrogen Peroxide/toxicity ; Mitochondria/drug effects ; Mitochondria/metabolism

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Skocz do pozycji: 6.

Tytuł:: Uncovering the Metabolic and Stress Responses of Human Embryonic Stem Cells to FTH1 Gene Silencing.
Autorzy:: Scaramuzzino L; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Lucchino V; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Scalise S; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Lo Conte M; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Zannino C; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Sacco A; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Biamonte F; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.; Center of Interdepartmental Services (CIS), 'Magna Graecia' University of Catanzaro, 88100 Catanzaro, Italy.
Parrotta EI; Department of Medical and Surgical Sciences, University Magna Graecia, 88100 Catanzaro, Italy.
Costanzo FS; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.; Center of Interdepartmental Services (CIS), 'Magna Graecia' University of Catanzaro, 88100 Catanzaro, Italy.
Cuda G; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Sep 15; Vol. 10 (9). Date of Electronic Publication: 2021 Sep 15.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Oxidative Stress*
Ferritins/*genetics
Human Embryonic Stem Cells/*metabolism
NF-E2-Related Factor 2/*metabolism
Oxidoreductases/*genetics
Antioxidant Response Elements ; Apoptosis ; Cell Differentiation ; Cells, Cultured ; Ferritins/pharmacology ; Gene Silencing ; Humans ; Oxidation-Reduction ; Oxidoreductases/metabolism ; Pentose Phosphate Pathway ; Signal Transduction

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Skocz do pozycji: 7.

Tytuł:: Enriched environment improves post-stroke cognitive impairment and inhibits neuroinflammation and oxidative stress by activating Nrf2-ARE pathway.
Autorzy:: Zhang X; School of Kinesiology, Shanghai University of Sport, Shanghai, China.
Yuan M; School of Kinesiology, Shanghai University of Sport, Shanghai, China.
Yang S; Department of Rehabilitation Medicine, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Chen X; Department of Rehabilitation Medicine, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Wu J; Department of Rehabilitation Medicine, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Wen M; Department of Rehabilitation Medicine, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Yan K; Department of Rehabilitation Medicine, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Bi X; Department of Rehabilitation Medicine, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.; Pokaż więcej
Źródło:: The International journal of neuroscience [Int J Neurosci] 2021 Jul; Vol. 131 (7), pp. 641-649. Date of Electronic Publication: 2020 Jul 27.
Typ publikacji:: Journal Article
MeSH Terms:: Cognitive Dysfunction*/etiology
Cognitive Dysfunction*/metabolism
Cognitive Dysfunction*/therapy
Environment*
Ischemic Stroke*/complications
Ischemic Stroke*/metabolism
Ischemic Stroke*/therapy
Neuroinflammatory Diseases*/etiology
Neuroinflammatory Diseases*/metabolism
Neuroinflammatory Diseases*/therapy
Oxidative Stress*
Stroke Rehabilitation*
Antioxidant Response Elements/*physiology
NF-E2-Related Factor 2/*metabolism
Animals ; Disease Models, Animal ; Infarction, Middle Cerebral Artery/complications ; Male ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/physiology

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Skocz do pozycji: 8.

Tytuł:: N -Phenyl Cinnamamide Derivatives Protect Hepatocytes against Oxidative Stress by Inducing Cellular Glutathione Synthesis via Nuclear Factor (Erythroid-Derived 2)-Like 2 Activation.
Autorzy:: Kim SH; College of Pharmacy, Pusan National University, Busan 46241, Korea.
Kim M; College of Pharmacy, Kyungsung University, Busan 48434, Korea.
Kwon D; College of Pharmacy, Pusan National University, Busan 46241, Korea.
Pyo JS; College of Pharmacy, Kyungsung University, Busan 48434, Korea.
Kim JH; Department of Polymer Engineering, Pukyong National University, Busan 48547, Korea.
Kwak JH; College of Pharmacy, Kyungsung University, Busan 48434, Korea.
Jung YS; College of Pharmacy, Pusan National University, Busan 46241, Korea.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Feb 15; Vol. 26 (4). Date of Electronic Publication: 2021 Feb 15.
Typ publikacji:: Journal Article
MeSH Terms:: Cinnamates/*pharmacology
Cytoprotection/*drug effects
Glutathione/*biosynthesis
Hepatocytes/*pathology
NF-E2-Related Factor 2/*metabolism
Oxidative Stress/*drug effects
Antioxidant Response Elements/genetics ; Carboxylic Acids/chemistry ; Carboxylic Acids/pharmacology ; Cell Death/drug effects ; Cinnamates/chemistry ; Glutathione/metabolism ; Hep G2 Cells ; Hepatocytes/drug effects ; Humans ; Luciferases/metabolism ; NF-E2-Related Factor 2/agonists ; Protective Agents/pharmacology ; tert-Butylhydroperoxide

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Skocz do pozycji: 9.

Tytuł:: 5-Caffeoylquinic acid ameliorates oxidative stress-mediated cell death via Nrf2 activation in hepatocytes.
Autorzy:: Chen X; College of Pharmacy, Chosun University, Gwangju, Republic of Korea.; Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, Shandong, China.
Yang JH; College of Pharmacy, Chosun University, Gwangju, Republic of Korea.; College of Korean Medicine, Dongshin University, Naju, Jeollanam-do, Republic of Korea.
Cho SS; College of Pharmacy, Chosun University, Gwangju, Republic of Korea.
Kim JH; College of Pharmacy, Chosun University, Gwangju, Republic of Korea.
Xu J; Department of Biochemistry and Molecular Cell Biology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Seo K; College of Pharmacy, Chosun University, Gwangju, Republic of Korea.
Ki SH; College of Pharmacy, Chosun University, Gwangju, Republic of Korea.; Pokaż więcej
Źródło:: Pharmaceutical biology [Pharm Biol] 2020 Dec; Vol. 58 (1), pp. 999-1005.
Typ publikacji:: Journal Article
MeSH Terms:: Cell Death/*drug effects
Hepatocytes/*drug effects
Oxidative Stress/*drug effects
Quinic Acid/*analogs & derivatives
Antioxidant Response Elements/drug effects ; Antioxidants/metabolism ; Dose-Response Relationship, Drug ; Gene Knockout Techniques ; Glutathione/metabolism ; Hep G2 Cells ; Hepatocytes/metabolism ; Humans ; NF-E2-Related Factor 2/metabolism ; Protective Agents/administration & dosage ; Protective Agents/pharmacology ; Quinic Acid/administration & dosage ; Quinic Acid/pharmacology ; Reactive Oxygen Species/metabolism

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Skocz do pozycji: 10.

Tytuł:: 6-Shogaol Protects Human Melanocytes against Oxidative Stress through Activation of the Nrf2-Antioxidant Response Element Signaling Pathway.
Autorzy:: Yang L; Department of Pigmentation Research and Therapeutics, Graduate School of Medicine, Osaka City University, Osaka 545-0041, Japan.; Department of Dermatology, Course of Integrated Medicine, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.
Yang F; Department of Dermatology, Course of Integrated Medicine, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.
Teng L; Department of Dermatology, Course of Integrated Medicine, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.
Katayama I; Department of Pigmentation Research and Therapeutics, Graduate School of Medicine, Osaka City University, Osaka 545-0041, Japan.; Department of Dermatology, Course of Integrated Medicine, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 May 16; Vol. 21 (10). Date of Electronic Publication: 2020 May 16.
Typ publikacji:: Journal Article
MeSH Terms:: Cytoprotection*/drug effects
Oxidative Stress*/drug effects
Oxidative Stress*/genetics
Signal Transduction*
Antioxidant Response Elements/*genetics
Catechols/*pharmacology
Melanocytes/*metabolism
Melanocytes/*pathology
NF-E2-Related Factor 2/*metabolism
Butanols ; Cell Death/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Epidermis/pathology ; Gene Expression Regulation/drug effects ; Humans ; Hydrogen Peroxide/toxicity ; Infant, Newborn ; Melanins/biosynthesis ; Melanocytes/drug effects

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Skocz do pozycji: 11.

Tytuł:: Melatonin as a potential modulator of Nrf2.
Autorzy:: Ahmadi Z; Department of basic science, Shoushtar Branch, Islamic Azad university, Shoushtar, 5563584, Iran.
Ashrafizadeh M; Department of basic science, Faculty of veterinary medicine, University of Tabriz, Tabriz, 1455742, Iran.; Pokaż więcej
Źródło:: Fundamental & clinical pharmacology [Fundam Clin Pharmacol] 2020 Feb; Vol. 34 (1), pp. 11-19. Date of Electronic Publication: 2019 Jul 31.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Melatonin/*pharmacology
NF-E2-Related Factor 2/*drug effects
Oxidative Stress/*drug effects
Animals ; Anti-Inflammatory Agents/pharmacology ; Antioxidant Response Elements ; Antioxidants/pharmacology ; Humans ; NF-E2-Related Factor 2/metabolism ; Oxidation-Reduction/drug effects ; Signal Transduction/drug effects

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Skocz do pozycji: 12.

Tytuł:: Ginsenoside Rg1 prevents acetaminophen-induced oxidative stress and apoptosis via Nrf2/ARE signaling pathway.
Autorzy:: Gao Y; a Department of Pharmacology, State Key Laboratory of Bioactive Substances and Functions of Natural Medicines , Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Chu SF; b College of Pharmacy , Hunan University of Chinese Medicine, Changsha 410208, China.
Zhang Z; a Department of Pharmacology, State Key Laboratory of Bioactive Substances and Functions of Natural Medicines , Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Ai QD; b College of Pharmacy , Hunan University of Chinese Medicine, Changsha 410208, China.
Xia CY; a Department of Pharmacology, State Key Laboratory of Bioactive Substances and Functions of Natural Medicines , Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Huang HY; b College of Pharmacy , Hunan University of Chinese Medicine, Changsha 410208, China.
Chen NH; a Department of Pharmacology, State Key Laboratory of Bioactive Substances and Functions of Natural Medicines , Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.; b College of Pharmacy , Hunan University of Chinese Medicine, Changsha 410208, China.; Pokaż więcej
Źródło:: Journal of Asian natural products research [J Asian Nat Prod Res] 2019 Aug; Vol. 21 (8), pp. 782-797. Date of Electronic Publication: 2019 Jan 04.
Typ publikacji:: Journal Article
MeSH Terms:: Acetaminophen/*toxicity
Antioxidant Response Elements/*physiology
Apoptosis/*drug effects
Ginsenosides/*pharmacology
NF-E2-Related Factor 2/*physiology
Oxidative Stress/*drug effects
Animals ; Antioxidants/pharmacology ; HEK293 Cells ; Hep G2 Cells ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Signal Transduction/drug effects

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Skocz do pozycji: 13.

Tytuł:: Sulforaphane prevents PC12 cells from oxidative damage via the Nrf2 pathway.
Autorzy:: Bao B; Department of Neurology, The Affiliated Hospital of Jiujiang College, Jiujiang, Jiangxi 33200, P.R. China.
Zhang MQ; Department of Neurology, The Affiliated Hospital of Jiujiang College, Jiujiang, Jiangxi 33200, P.R. China.
Chen ZY; Department of Neurology, The Affiliated Hospital of Jiujiang College, Jiujiang, Jiangxi 33200, P.R. China.
Wu XB; Department of Neurology, The Affiliated Hospital of Jiujiang College, Jiujiang, Jiangxi 33200, P.R. China.
Xia ZB; Department of Neurology, The Affiliated Hospital of Jiujiang College, Jiujiang, Jiangxi 33200, P.R. China.
Chai JY; Department of Neurology, The Affiliated Hospital of Jiujiang College, Jiujiang, Jiangxi 33200, P.R. China.
Yin XP; Department of Neurology, The Affiliated Hospital of Jiujiang College, Jiujiang, Jiangxi 33200, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2019 Jun; Vol. 19 (6), pp. 4890-4896. Date of Electronic Publication: 2019 Apr 10.
Typ publikacji:: Journal Article
MeSH Terms:: Isothiocyanates/*pharmacology
NF-E2-Related Factor 2/*metabolism
Oxidative Stress/*drug effects
PC12 Cells/*drug effects
Protective Agents/*pharmacology
1-Methyl-4-phenylpyridinium/toxicity ; Animals ; Antioxidant Response Elements ; Antioxidants/pharmacology ; Antiparkinson Agents/pharmacology ; Apoptosis/drug effects ; Cell Survival/drug effects ; Heme Oxygenase-1/metabolism ; Isothiocyanates/administration & dosage ; NAD(P)H Dehydrogenase (Quinone)/metabolism ; Parkinson Disease/drug therapy ; Rats ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects ; Sulfoxides ; Survival Rate ; Time Factors

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Skocz do pozycji: 14.

Tytuł:: Role of Nuclear Factor Erythroid 2-Related Factor 2 in Diabetic Nephropathy.
Autorzy:: Cui W; Department of Nephrology, The Second Hospital of Jilin University, Changchun, Jilin 130041, China.
Min X; Department of Nephrology, The Second Hospital of Jilin University, Changchun, Jilin 130041, China.
Xu X; Department of Gynaecology and Obstetrics, The Second Hospital of Jilin University, Changchun, Jilin 130041, China.
Du B; Department of Cardiology, The First Hospital of Jilin University, Changchun, Jilin 130031, China.
Luo P; Department of Nephrology, The Second Hospital of Jilin University, Changchun, Jilin 130041, China.; Pokaż więcej
Źródło:: Journal of diabetes research [J Diabetes Res] 2017; Vol. 2017, pp. 3797802. Date of Electronic Publication: 2017 Apr 23.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Antioxidant Response Elements*
Oxidative Stress*
Diabetic Nephropathies/*metabolism
NF-E2-Related Factor 2/*metabolism
Animals ; Anticarcinogenic Agents/therapeutic use ; Antioxidants/therapeutic use ; Curcumin/therapeutic use ; Cysteine Proteinase Inhibitors/therapeutic use ; Diabetic Nephropathies/drug therapy ; Enzyme Inhibitors/therapeutic use ; Humans ; Isothiocyanates/therapeutic use ; Leupeptins/therapeutic use ; Molecular Targeted Therapy ; Resveratrol ; Rutin/therapeutic use ; Signal Transduction ; Stilbenes/therapeutic use ; Sulfoxides ; Trace Elements/therapeutic use ; Zinc/therapeutic use

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Skocz do pozycji: 15.

Tytuł:: SGLT2 inhibition with empagliflozin attenuates myocardial oxidative stress and fibrosis in diabetic mice heart.
Autorzy:: Li C; NHC Key Laboratory of Hormones and Development (Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin, 300070, China.
Zhang J; NHC Key Laboratory of Hormones and Development (Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin, 300070, China.
Xue M; NHC Key Laboratory of Hormones and Development (Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin, 300070, China.
Li X; NHC Key Laboratory of Hormones and Development (Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin, 300070, China.
Han F; NHC Key Laboratory of Hormones and Development (Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin, 300070, China.
Liu X; NHC Key Laboratory of Hormones and Development (Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin, 300070, China.
Xu L; NHC Key Laboratory of Hormones and Development (Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin, 300070, China.
Lu Y; NHC Key Laboratory of Hormones and Development (Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin, 300070, China.
Cheng Y; NHC Key Laboratory of Hormones and Development (Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin, 300070, China.
Li T; NHC Key Laboratory of Hormones and Development (Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin, 300070, China.
Yu X; NHC Key Laboratory of Hormones and Development (Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin, 300070, China.
Sun B; NHC Key Laboratory of Hormones and Development (Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin, 300070, China. sun_.
Chen L; NHC Key Laboratory of Hormones and Development (Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin, 300070, China. .; Pokaż więcej
Źródło:: Cardiovascular diabetology [Cardiovasc Diabetol] 2019 Feb 02; Vol. 18 (1), pp. 15. Date of Electronic Publication: 2019 Feb 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antioxidants/*pharmacology
Benzhydryl Compounds/*pharmacology
Diabetes Mellitus, Type 2/*drug therapy
Diabetic Cardiomyopathies/*prevention & control
Glucosides/*pharmacology
Myocardium/*metabolism
Oxidative Stress/*drug effects
Sodium-Glucose Transporter 2 Inhibitors/*pharmacology
Ventricular Function, Left/*drug effects
Ventricular Remodeling/*drug effects
Animals ; Antioxidant Response Elements ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/metabolism ; Diabetic Cardiomyopathies/etiology ; Diabetic Cardiomyopathies/metabolism ; Diabetic Cardiomyopathies/physiopathology ; Disease Models, Animal ; Fibrosis ; Mice, Inbred C57BL ; Myocardium/pathology ; NF-E2-Related Factor 2/metabolism ; Phosphorylation ; Signal Transduction/drug effects ; Smad Proteins/metabolism ; Sodium-Glucose Transporter 2/metabolism ; Transforming Growth Factor beta1/metabolism

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Tytuł:: Activation of the KEAP1‑NRF2‑ARE signaling pathway reduces oxidative stress in Hep2 cells.
Autorzy:: Li C; Department of Otorhinolaryngology‑Head and Neck Surgery, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Fudan University, Shanghai 200031, P.R. China.
Cheng L; Department of Otorhinolaryngology‑Head and Neck Surgery, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Fudan University, Shanghai 200031, P.R. China.
Wu H; Department of Otorhinolaryngology‑Head and Neck Surgery, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Fudan University, Shanghai 200031, P.R. China.
He P; Department of Otorhinolaryngology‑Head and Neck Surgery, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Fudan University, Shanghai 200031, P.R. China.
Zhang Y; Department of Central Laboratory, Eye, Ear, Nose and Throat Hospital, Fudan University, Shanghai 200031, P.R. China.
Yang Y; Department of Otorhinolaryngology‑Head and Neck Surgery, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Fudan University, Shanghai 200031, P.R. China.
Chen J; Department of Otorhinolaryngology‑Head and Neck Surgery, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Fudan University, Shanghai 200031, P.R. China.
Chen M; Department of Otorhinolaryngology‑Head and Neck Surgery, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Fudan University, Shanghai 200031, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Sep; Vol. 18 (3), pp. 2541-2550. Date of Electronic Publication: 2018 Jul 16.
Typ publikacji:: Journal Article
MeSH Terms:: Oxidative Stress*/drug effects
Antioxidant Response Elements/*genetics
Kelch-Like ECH-Associated Protein 1/*metabolism
NF-E2-Related Factor 2/*metabolism
Cell Line ; Gene Expression/drug effects ; Heme Oxygenase-1/genetics ; Heme Oxygenase-1/metabolism ; Humans ; Hydrogen Peroxide/pharmacology ; Kelch-Like ECH-Associated Protein 1/antagonists & inhibitors ; Kelch-Like ECH-Associated Protein 1/genetics ; Microscopy, Fluorescence ; NAD(P)H Dehydrogenase (Quinone)/genetics ; NAD(P)H Dehydrogenase (Quinone)/metabolism ; NF-E2-Related Factor 2/genetics ; RNA Interference ; RNA, Small Interfering/metabolism ; Signal Transduction/drug effects

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Tytuł:: Cytoprotective effects of diosmetin against hydrogen peroxide-induced L02 cell oxidative damage via activation of the Nrf2-ARE signaling pathway.
Autorzy:: Wang C; Department of Life Sciences, Bengbu Medical College, Bengbu, Anhui 233030, P.R. China.
Liao Y; Department of Life Sciences, Bengbu Medical College, Bengbu, Anhui 233030, P.R. China.
Wang S; Department of Life Sciences, Bengbu Medical College, Bengbu, Anhui 233030, P.R. China.
Wang D; Department of Life Sciences, Bengbu Medical College, Bengbu, Anhui 233030, P.R. China.
Wu N; Department of Life Sciences, Bengbu Medical College, Bengbu, Anhui 233030, P.R. China.
Xu Q; Department of Life Sciences, Bengbu Medical College, Bengbu, Anhui 233030, P.R. China.
Jiang W; Department of Life Sciences, Bengbu Medical College, Bengbu, Anhui 233030, P.R. China.
Qiu M; Department of Life Sciences, Bengbu Medical College, Bengbu, Anhui 233030, P.R. China.
Liu C; Department of Life Sciences, Bengbu Medical College, Bengbu, Anhui 233030, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 May; Vol. 17 (5), pp. 7331-7338. Date of Electronic Publication: 2018 Mar 15.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidant Response Elements/*drug effects
Antioxidants/*pharmacology
Cytoprotection/*drug effects
Flavonoids/*pharmacology
NF-E2-Related Factor 2/*metabolism
Oxidative Stress/*drug effects
Signal Transduction/*drug effects
Apoptosis/drug effects ; Cell Line ; Hepatocytes/cytology ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Humans ; Hydrogen Peroxide/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Reactive Oxygen Species/metabolism

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Skocz do pozycji: 18.

Tytuł:: Eriodictyol Protects Endothelial Cells against Oxidative Stress-Induced Cell Death through Modulating ERK/Nrf2/ARE-Dependent Heme Oxygenase-1 Expression.
Autorzy:: Lee SE; Department of Microbiology, School of Medicine, Kyung Hee University, Seoul 130-701, Korea. .
Yang H; Department of Microbiology, School of Medicine, Kyung Hee University, Seoul 130-701, Korea. .
Son GW; Department of Microbiology, School of Medicine, Kyung Hee University, Seoul 130-701, Korea. .
Park HR; Department of Microbiology, School of Medicine, Kyung Hee University, Seoul 130-701, Korea. .
Park CS; Department of Microbiology, School of Medicine, Kyung Hee University, Seoul 130-701, Korea. .
Jin YH; Department of Physiology, School of Medicine, Kyung Hee University, Seoul 130-701, Korea. .
Park YS; Department of Microbiology, School of Medicine, Kyung Hee University, Seoul 130-701, Korea. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2015 Jun 26; Vol. 16 (7), pp. 14526-39. Date of Electronic Publication: 2015 Jun 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antioxidant Response Elements*
Oxidative Stress*
Antioxidants/*pharmacology
Flavanones/*pharmacology
Heme Oxygenase-1/*metabolism
Human Umbilical Vein Endothelial Cells/*drug effects
NF-E2-Related Factor 2/*metabolism
Cell Death ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Heme Oxygenase-1/genetics ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Hydrogen Peroxide/toxicity ; NF-E2-Related Factor 2/genetics ; Up-Regulation

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Skocz do pozycji: 19.

Tytuł:: Protective effects and functional mechanisms of Lactobacillus gasseri SBT2055 against oxidative stress.
Autorzy:: Kobatake E; Milk Science Research Institute, Megmilk Snow Brand Co., Ltd., Saitama, Japan.
Nakagawa H; Department of Probiotics Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan.
Seki T; Milk Science Research Institute, Megmilk Snow Brand Co., Ltd., Saitama, Japan.
Miyazaki T; Department of Probiotics Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 May 11; Vol. 12 (5), pp. e0177106. Date of Electronic Publication: 2017 May 11 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Oxidative Stress*
Fibroblasts/*metabolism
Fibroblasts/*microbiology
Lactobacillus gasseri/*metabolism
Probiotics/*metabolism
Animals ; Antioxidant Response Elements ; Cell Proliferation ; Cells, Cultured ; Fibroblasts/cytology ; JNK Mitogen-Activated Protein Kinases/metabolism ; MAP Kinase Signaling System ; Mice ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; NIH 3T3 Cells ; Signal Transduction

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Tytuł:: Gene expression profiles in preterm infants on continuous long‑term oxygen therapy suggest reduced oxidative stress‑dependent signaling during hypoxia.
Autorzy:: Kalikstad B; University of Oslo, Institute of Clinical Medicine, Women and Children's Clinic, Rikshospitalet, 0372 Oslo, Norway.
Kultima HG; Department of Medical Sciences, Science for Life Laboratory, Uppsala University, 751 23 Uppsala, Sweden.
Andersstuen TK; Department of Molecular Biology, Institute of Medical Microbiology, Oslo University Hospital, Rikshospitalet, 0372 Oslo, Norway.
Klungland A; Department of Molecular Biology, Institute of Medical Microbiology, Oslo University Hospital, Rikshospitalet, 0372 Oslo, Norway.
Isaksson A; Department of Medical Sciences, Science for Life Laboratory, Uppsala University, 751 23 Uppsala, Sweden.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2017 Apr; Vol. 15 (4), pp. 1513-1526. Date of Electronic Publication: 2017 Feb 08.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Profiling*
Hypoxia/*genetics
Infant, Premature/*metabolism
Oxidative Stress/*genetics
Oxygen/*therapeutic use
Signal Transduction/*genetics
Antioxidant Response Elements/genetics ; Cohort Studies ; Female ; Gene Expression Regulation ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Infant ; Infant, Newborn ; Male ; Molecular Sequence Annotation ; NF-E2-Related Factor 2/metabolism ; Time Factors ; Transcriptome

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