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Wyszukujesz frazę ""apoptosis"" wg kryterium: Temat


Tytuł :
[Effect of DR4 Demethylation to the Proliferation and Apoptosis of Myeloid Leukemia K562 Cells].
Autorzy :
Zhang M; Department of Hematology, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang 471000, Henan Province, China.
Cai LH; Department of Hematology, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang 471000, Henan Province, China.
Yang HP; Department of Hematology, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang 471000, Henan Province, China,E-mail:.
Yang XW; Department of Hematology, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang 471000, Henan Province, China.
Si XH; Xinxiang Medical College, Xinxiang 453003, Henan Province, China.
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Źródło :
Zhongguo shi yan xue ye xue za zhi [Zhongguo Shi Yan Xue Ye Xue Za Zhi] 2021 Apr; Vol. 29 (2), pp. 422-427.
Typ publikacji :
Journal Article
MeSH Terms :
Leukemia, Myeloid*
Receptors, TNF-Related Apoptosis-Inducing Ligand*/metabolism
Apoptosis ; Cell Line, Tumor ; Cell Proliferation ; Demethylation ; Humans ; K562 Cells ; TNF-Related Apoptosis-Inducing Ligand/metabolism
Czasopismo naukowe
Tytuł :
Downregulation of ARID1A in gastric cancer cells: a putative protective molecular mechanism against the Harakiri-mediated apoptosis pathway.
Autorzy :
Sakuratani T; Department of Surgical Oncology, Gifu University Graduate School of Medicine, Gifu, Japan.
Takeuchi T; Department of Pathology and Translational Research, Gifu University Graduate School of Medicine, Gifu, 501-1193, Japan. .
Yasufuku I; Department of Surgical Oncology, Gifu University Graduate School of Medicine, Gifu, Japan.
Iwata Y; Department of Surgical Oncology, Gifu University Graduate School of Medicine, Gifu, Japan.
Saigo C; Department of Pathology and Translational Research, Gifu University Graduate School of Medicine, Gifu, 501-1193, Japan.
Kito Y; Department of Pathology and Translational Research, Gifu University Graduate School of Medicine, Gifu, 501-1193, Japan.
Yoshida K; Department of Surgical Oncology, Gifu University Graduate School of Medicine, Gifu, Japan.
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 Mar; Vol. 478 (3), pp. 401-411. Date of Electronic Publication: 2020 Aug 13.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*/drug effects
Apoptosis Regulatory Proteins/*metabolism
Biomarkers, Tumor/*metabolism
DNA-Binding Proteins/*metabolism
Stomach Neoplasms/*metabolism
Transcription Factors/*metabolism
Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents/pharmacology ; Apoptosis Regulatory Proteins/genetics ; Biomarkers, Tumor/genetics ; Caprylates/pharmacology ; Cell Line, Tumor ; DNA-Binding Proteins/genetics ; Down-Regulation ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Signal Transduction ; Stomach Neoplasms/drug therapy ; Stomach Neoplasms/genetics ; Stomach Neoplasms/pathology ; Sulfides/pharmacology ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
ROS-Mediated Apoptosis and Autophagy in Ovarian Cancer Cells Treated with Peanut-Shaped Gold Nanoparticles.
Autorzy :
Piktel E; Department of Medical Microbiology and Nanobiomedical Engineering, Medical University of Bialystok, Bialystok, 15-222, Poland.
Ościłowska I; Department of Medicinal Chemistry, Medical University of Bialystok, Bialystok, 15-222, Poland.
Suprewicz Ł; Department of Medical Microbiology and Nanobiomedical Engineering, Medical University of Bialystok, Bialystok, 15-222, Poland.
Depciuch J; Institute of Nuclear Physics Polish Academy of Sciences, Krakow, PL-31342, Poland.
Marcińczyk N; Department of Biopharmacy, Medical University of Bialystok, Bialystok, 15-222, Poland.
Chabielska E; Department of Biopharmacy, Medical University of Bialystok, Bialystok, 15-222, Poland.
Wolak P; Institute of Medical Sciences, Collegium Medicum, Jan Kochanowski University, Kielce, 25-317, Poland.
Wollny T; Holy Cross Cancer Center in Kielce, Kielce, 25-734, Poland.
Janion M; Institute of Medical Sciences, Collegium Medicum, Jan Kochanowski University, Kielce, 25-317, Poland.
Parlinska-Wojtan M; Institute of Nuclear Physics Polish Academy of Sciences, Krakow, PL-31342, Poland.
Bucki R; Department of Medical Microbiology and Nanobiomedical Engineering, Medical University of Bialystok, Bialystok, 15-222, Poland.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2021 Mar 09; Vol. 16, pp. 1993-2011. Date of Electronic Publication: 2021 Mar 09 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*/drug effects
Autophagy*/drug effects
Gold/*chemistry
Metal Nanoparticles/*chemistry
Ovarian Neoplasms/*pathology
Reactive Oxygen Species/*metabolism
Apoptosis Regulatory Proteins/metabolism ; Arachis ; Carcinoma, Ovarian Epithelial/drug therapy ; Cell Line, Tumor ; Cell Survival/drug effects ; Female ; Humans ; MAP Kinase Signaling System/drug effects ; Metal Nanoparticles/toxicity ; Metal Nanoparticles/ultrastructure ; Ovarian Neoplasms/drug therapy ; Oxidation-Reduction
Czasopismo naukowe
Tytuł :
ABHD15 promotes cell viability, glycolysis, and inhibits apoptosis in cardiomyocytes under hypoxia.
Autorzy :
Huang G; Cardiology Department, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.
Guo X; Cardiology Department, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.
Guo J; Cardiology Department, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.
Zhang P; Cardiology Department, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.
Liang W; Cardiology Department, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.
Bai C; Cardiology Department, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.
Zhang Y; Cardiology Department, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China. Electronic address: .
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Źródło :
Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2021 Feb 08; Vol. 31 (2), pp. 681-690. Date of Electronic Publication: 2020 Oct 09.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Glycolysis*
Carboxylic Ester Hydrolases/*metabolism
Membrane Proteins/*metabolism
Myocardial Infarction/*enzymology
Myocytes, Cardiac/*enzymology
Animals ; Apoptosis Regulatory Proteins/metabolism ; Carboxylic Ester Hydrolases/genetics ; Cell Hypoxia ; Cell Line ; Cell Survival ; Glucose Transporter Type 4/metabolism ; Humans ; Membrane Proteins/genetics ; Myocardial Infarction/genetics ; Myocardial Infarction/pathology ; Myocytes, Cardiac/pathology ; Phosphorylation ; Rats ; Receptor, Insulin/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Identification and functional analyses of a cell-death inhibitor encoded by guinea pig cytomegalovirus gp38.1 in cell culture and in animals.
Autorzy :
Noguchi K; Present address: Kaken Pharmaceutical, Tokyo, Japan.; Microbiology and Immunology, Gifu Pharmaceutical University, Gifu, Japan.
Majima R; Microbiology and Immunology, Gifu Pharmaceutical University, Gifu, Japan.
Takahashi K; Microbiology and Immunology, Gifu Pharmaceutical University, Gifu, Japan.
Iwase Y; Microbiology and Immunology, Gifu Pharmaceutical University, Gifu, Japan.
Yamada S; Department of Virology I, National Institute of Infectious Diseases, Tokyo, Japan.
Satoh K; Microbiology and Immunology, Gifu Pharmaceutical University, Gifu, Japan.
Koshizuka T; Microbiology and Immunology, Gifu Pharmaceutical University, Gifu, Japan.
Inoue N; Microbiology and Immunology, Gifu Pharmaceutical University, Gifu, Japan.
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Źródło :
The Journal of general virology [J Gen Virol] 2020 Dec; Vol. 101 (12), pp. 1270-1279. Date of Electronic Publication: 2020 Sep 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Apoptosis Regulatory Proteins/*metabolism
Roseolovirus/*genetics
Roseolovirus/*physiology
Viral Proteins/*metabolism
Animals ; Apoptosis Regulatory Proteins/genetics ; Cell Survival ; Cells, Cultured ; Genome, Viral ; Glycosylation ; Guinea Pigs ; Mitochondria/metabolism ; Open Reading Frames ; Roseolovirus/growth & development ; Roseolovirus Infections/virology ; Viral Load ; Viral Proteins/genetics ; bcl-2 Homologous Antagonist-Killer Protein/metabolism ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł :
Ultrasonic irradiation and SonoVue microbubbles-mediated RNA interference targeting PRR11 inhibits breast cancer cells proliferation and metastasis, but promotes apoptosis.
Autorzy :
Luo H; Department of Ultrasound, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.; Shenzhen Medical Ultrasound Engineering Center, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.
Li J; Department of Ultrasound, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.; Shenzhen Medical Ultrasound Engineering Center, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.
Lin Q; Department of Ultrasound, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.; Shenzhen Medical Ultrasound Engineering Center, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.
Xiao X; Department of Ultrasound, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.; Shenzhen Medical Ultrasound Engineering Center, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.
Shi Y; Department of Ultrasound, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.; Shenzhen Medical Ultrasound Engineering Center, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.
Ye X; Department of Ultrasound, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.; Shenzhen Medical Ultrasound Engineering Center, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.
Wei Z; Department of Ultrasound, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.; Shenzhen Medical Ultrasound Engineering Center, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.
Liu Y; Department of Ultrasound, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.; Shenzhen Medical Ultrasound Engineering Center, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.
Xu J; Department of Ultrasound, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.; Shenzhen Medical Ultrasound Engineering Center, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.
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Źródło :
Bioscience reports [Biosci Rep] 2020 Nov 27; Vol. 40 (11).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Cell Movement*
Cell Proliferation*
RNAi Therapeutics*
Transfection*
Ultrasonic Waves*
Breast Neoplasms/*therapy
Phospholipids/*chemistry
Proteins/*genetics
RNA, Small Interfering/*genetics
Sulfur Hexafluoride/*chemistry
Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Epithelial-Mesenchymal Transition ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Lipids/chemistry ; MCF-7 Cells ; Microbubbles ; Neoplasm Invasiveness ; Proteins/metabolism ; RNA Interference ; RNA, Small Interfering/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Inhibition of Wnt signalling pathway by XAV939 enhances radiosensitivity in human cervical cancer HeLa cells.
Autorzy :
Zhang J; Department of Radiation Medicine, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.; Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Si J; Department of Radiation Medicine, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.; Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Gan L; Department of Radiation Medicine, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.; Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Guo M; School of Pharmacy, Lanzhou University, Lanzhou, China.
Yan J; Department of Radiation Medicine, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.; Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Chen Y; Department of Radiation Medicine, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.; Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Wang F; Department of Radiation Medicine, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.; Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Xie Y; Department of Radiation Medicine, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.; Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Wang Y; Department of Radiation Medicine, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.; Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Zhang H; Department of Radiation Medicine, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.; Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
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Źródło :
Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2020 Dec; Vol. 48 (1), pp. 479-487.
Typ publikacji :
Journal Article; Video-Audio Media
MeSH Terms :
Apoptosis*/drug effects
Apoptosis*/radiation effects
Radiation Tolerance*/drug effects
Radiation Tolerance*/radiation effects
Uterine Cervical Neoplasms*/metabolism
Uterine Cervical Neoplasms*/pathology
Uterine Cervical Neoplasms*/radiotherapy
Wnt Signaling Pathway*/drug effects
Wnt Signaling Pathway*/radiation effects
Heterocyclic Compounds, 3-Ring/*pharmacology
Apoptosis Regulatory Proteins/metabolism ; Female ; G2 Phase Cell Cycle Checkpoints/drug effects ; G2 Phase Cell Cycle Checkpoints/radiation effects ; HeLa Cells ; Humans ; M Phase Cell Cycle Checkpoints/drug effects ; M Phase Cell Cycle Checkpoints/radiation effects ; Neoplasm Proteins/metabolism
Czasopismo naukowe
Tytuł :
Mcl-1 targeting strategies unlock the proapoptotic potential of TRAIL in melanoma cells.
Autorzy :
Sarif Z; Department of Dermatology, Venerology, and Allergology, Skin Cancer Center Charité, Charité-Universitätsmedizin Berlin (University Medical Center Charité), Berlin, Germany.
Tolksdorf B; Department of Applied Biochemistry, Institute of Biotechnology, Technical University of Berlin, Berlin, Germany.
Fechner H; Department of Applied Biochemistry, Institute of Biotechnology, Technical University of Berlin, Berlin, Germany.
Eberle J; Department of Dermatology, Venerology, and Allergology, Skin Cancer Center Charité, Charité-Universitätsmedizin Berlin (University Medical Center Charité), Berlin, Germany.
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Źródło :
Molecular carcinogenesis [Mol Carcinog] 2020 Nov; Vol. 59 (11), pp. 1256-1268. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Drug Resistance, Neoplasm*
Melanoma/*pathology
Myeloid Cell Leukemia Sequence 1 Protein/*antagonists & inhibitors
RNA, Small Interfering/*genetics
TNF-Related Apoptosis-Inducing Ligand/*metabolism
Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Cell Proliferation ; Gene Expression Regulation, Neoplastic ; Humans ; Melanoma/drug therapy ; Melanoma/genetics ; Melanoma/metabolism ; MicroRNAs/pharmacology ; Myeloid Cell Leukemia Sequence 1 Protein/genetics ; Myeloid Cell Leukemia Sequence 1 Protein/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Pyrimidines/pharmacology ; TNF-Related Apoptosis-Inducing Ligand/genetics ; Thiophenes/pharmacology ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
[Effect of small interfering RNA-mediated BIRC6 silencing on apoptosis and autophagy of renal cancer 786-O cells].
Autorzy :
Zhong K; Department of Urology, Meizhou People's Hospital, Meizhou 514031, China.
Chen D; Department of Urology, Sun Yat-sen Cancer Center, Guangzhou 510060, China.
Wu Z; Department of Urology, Sun Yat-sen Cancer Center, Guangzhou 510060, China.
Wang X; Department of Nephrology, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Pan B; Department of Urology, First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Chen N; Department of Urology, Meizhou People's Hospital, Meizhou 514031, China.
Zhong W; Department of Urology, Meizhou People's Hospital, Meizhou 514031, China.; Department of Urology, Sun Yat-sen Cancer Center, Guangzhou 510060, China.
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Źródło :
Nan fang yi ke da xue xue bao = Journal of Southern Medical University [Nan Fang Yi Ke Da Xue Xue Bao] 2020 Nov 30; Vol. 40 (11), pp. 1651-1655.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Autophagy*
Kidney Neoplasms*/genetics
Cell Line, Tumor ; Cell Proliferation ; Humans ; Inhibitor of Apoptosis Proteins/genetics ; RNA, Small Interfering/genetics
Czasopismo naukowe
Tytuł :
Combination of Scalp Acupuncture with Exercise Therapy Effectively Counteracts Ischemic Brain Injury in Rats.
Autorzy :
Li Z; Department of Rehabilitation, Pudong New Area People's Hospital affiliated to Shanghai University of Medicine & Health Sciences, Shanghai 201299, P. R. China.
Meng X; Department of Rehabilitation, Pudong New Area People's Hospital affiliated to Shanghai University of Medicine & Health Sciences, Shanghai 201299, P. R. China. Electronic address: .
Ren M; Department of Rehabilitation, Pudong New Area People's Hospital affiliated to Shanghai University of Medicine & Health Sciences, Shanghai 201299, P. R. China.
Shao M; Department of Rehabilitation, Pudong New Area People's Hospital affiliated to Shanghai University of Medicine & Health Sciences, Shanghai 201299, P. R. China.
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Nov; Vol. 29 (11), pp. 105286. Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Journal Article
MeSH Terms :
Acupuncture Points*
Acupuncture Therapy*
Apoptosis*
Exercise Therapy*
Scalp*
Brain/*pathology
Infarction, Middle Cerebral Artery/*prevention & control
Animals ; Apoptosis Regulatory Proteins/metabolism ; Behavior, Animal ; Brain/metabolism ; Brain/physiopathology ; Brain-Derived Neurotrophic Factor/metabolism ; Cytokines/metabolism ; Disease Models, Animal ; Glial Fibrillary Acidic Protein/metabolism ; Infarction, Middle Cerebral Artery/metabolism ; Infarction, Middle Cerebral Artery/pathology ; Infarction, Middle Cerebral Artery/psychology ; Inflammation Mediators/metabolism ; Male ; Necrosis ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; S100 Calcium Binding Protein beta Subunit/metabolism ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
Effects of Different Degrees of Carotid Artery Stenosis on the Expression of XIAP and Smac in the Ischemic Penumbra of Rats with Cerebral Ischemia-Reperfusion.
Autorzy :
Xiang RP; Department of Neurology, Changsha Hospital of Hunan Normal University, Changsha 410006, Hunan, China.
Zhou MJ; Department of Neurology, Changsha Hospital of Hunan Normal University, Changsha 410006, Hunan, China.
Cui R; Department of Intensive Care Unit, Changsha Hospital of Hunan Normal University, No.70 Lu-Shan Road, Changsha 410006, Hunan, China. Electronic address: .
Yu HY; Department of Neurology, Changsha Hospital of Hunan Normal University, Changsha 410006, Hunan, China.
Chen Q; Department of Neurology, Changsha Hospital of Hunan Normal University, Changsha 410006, Hunan, China.
Huang YJ; Department of Neurology, Changsha Hospital of Hunan Normal University, Changsha 410006, Hunan, China.
Li Z; Department of Neurology, Changsha Hospital of Hunan Normal University, Changsha 410006, Hunan, China.
Yu C; Department of Neurology, Changsha Hospital of Hunan Normal University, Changsha 410006, Hunan, China.
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2021 Feb; Vol. 30 (2), pp. 105516. Date of Electronic Publication: 2020 Dec 10.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Apoptosis Regulatory Proteins/*metabolism
Brain/*metabolism
Brain Ischemia/*etiology
Carotid Stenosis/*complications
Inhibitor of Apoptosis Proteins/*metabolism
Mitochondrial Proteins/*metabolism
Neurons/*metabolism
Reperfusion Injury/*etiology
Animals ; Apoptosis ; Apoptosis Regulatory Proteins/genetics ; Brain/pathology ; Brain Ischemia/pathology ; Disease Models, Animal ; Inhibitor of Apoptosis Proteins/genetics ; Male ; Mitochondrial Proteins/genetics ; Neurons/pathology ; Rats, Sprague-Dawley ; Reperfusion Injury/pathology ; Severity of Illness Index ; Signal Transduction ; Time Factors
Czasopismo naukowe
Tytuł :
ALG2 Influences T cell apoptosis by regulating FASLG intracellular transportation.
Autorzy :
Ji W; State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Protein Science, College of Life Sciences, Nankai University, Tianjin, China.
Xin Y; State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Protein Science, College of Life Sciences, Nankai University, Tianjin, China.
Zhang L; State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Protein Science, College of Life Sciences, Nankai University, Tianjin, China.
Liu X; State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Protein Science, College of Life Sciences, Nankai University, Tianjin, China.
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Źródło :
The Biochemical journal [Biochem J] 2020 Aug 28; Vol. 477 (16), pp. 3105-3121.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Apoptosis Regulatory Proteins/*metabolism
Fas Ligand Protein/*metabolism
Lymphocyte Activation/*immunology
T-Lymphocytes/*pathology
Apoptosis Regulatory Proteins/genetics ; Fas Ligand Protein/genetics ; HEK293 Cells ; HeLa Cells ; Humans ; Jurkat Cells ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
Peroxiredoxin V Silencing Elevates Susceptibility to Doxorubicin-induced Cell Apoptosis via ROS-dependent Mitochondrial Dysfunction in AGS Gastric Cancer Cells.
Autorzy :
Jin YZ; School of Nursing, Yanbian University, Yanji, P.R. China.; College of Medicine, Yanbian University, Yanji, P.R. China.
Gong YX; College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China.
Liu Y; College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China.
Xie DP; College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China.
Ren CX; College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China.
Lee SJ; Immunoregulatory Materials Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeonbuk, Republic of Korea.
Sun HN; College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China; .
Kwon T; Primate Resources Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeonbuk, Republic of Korea .
Xu DY; College of Medicine, Yanbian University, Yanji, P.R. China; .
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Źródło :
Anticancer research [Anticancer Res] 2021 Apr; Vol. 41 (4), pp. 1831-1840.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Silencing*
Adenocarcinoma/*drug therapy
Antibiotics, Antineoplastic/*pharmacology
Apoptosis/*drug effects
Doxorubicin/*pharmacology
Mitochondria/*drug effects
Oxidative Stress/*drug effects
Peroxiredoxins/*metabolism
Reactive Oxygen Species/*metabolism
Stomach Neoplasms/*drug therapy
Adenocarcinoma/enzymology ; Adenocarcinoma/genetics ; Adenocarcinoma/pathology ; Apoptosis Regulatory Proteins/metabolism ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Humans ; Mitochondria/enzymology ; Mitochondria/pathology ; Peroxiredoxins/genetics ; Signal Transduction ; Stomach Neoplasms/enzymology ; Stomach Neoplasms/genetics ; Stomach Neoplasms/pathology
Czasopismo naukowe
Tytuł :
TP53-induced glycolysis and apoptosis regulator (TIGAR) ameliorates lysosomal damage in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-mediated mouse model of Parkinson's disease.
Autorzy :
Ge J; Department of Pharmacology, School of Pharmacy, Nantong University, Nantong, 226001, Jiangsu, China; Department of Pharmacy, the Second People's Hospital of Nantong, Nantong, 226002, Jiangsu, China.
Lin H; Department of Pharmacology, School of Pharmacy, Nantong University, Nantong, 226001, Jiangsu, China.
Yang J; Department of Pharmacology, School of Pharmacy, Nantong University, Nantong, 226001, Jiangsu, China.
Li Q; Department of Pharmacology, School of Pharmacy, Nantong University, Nantong, 226001, Jiangsu, China.
Zhou J; Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Soochow University School of Pharmaceutical Sciences, Suzhou, 215123, Jiangsu, China.
Qin Z; Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Soochow University School of Pharmaceutical Sciences, Suzhou, 215123, Jiangsu, China.
Wu F; Department of Pharmacology, School of Pharmacy, Nantong University, Nantong, 226001, Jiangsu, China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2021 Mar 15; Vol. 339, pp. 60-69. Date of Electronic Publication: 2020 Dec 24.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis Regulatory Proteins/*therapeutic use
Glycolysis/*drug effects
Lysosomes/*drug effects
MPTP Poisoning/*drug therapy
MPTP Poisoning/*physiopathology
Parkinson Disease/*physiopathology
Phosphoric Monoester Hydrolases/*therapeutic use
Tumor Suppressor Protein p53/*therapeutic use
Animals ; Apoptosis/drug effects ; Cell Line, Tumor ; Disease Models, Animal ; Mice ; Mice, Inbred C57BL ; Models, Animal
Czasopismo naukowe
Tytuł :
Depleting microRNA-183-3p improves renal tubulointerstitial fibrosis after acute kidney injury via SIRT1/PUMA/FOXO3a deacetylation.
Autorzy :
Li H; Emergency and Critical Care Center, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, Hubei, China.
Chou P; Department of Nephrology, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, Hubei, China.
Du F; Emergency and Critical Care Center, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, Hubei, China.
Sun L; Emergency and Critical Care Center, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, Hubei, China.
Liu J; Emergency and Critical Care Center, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, Hubei, China. Electronic address: .
Wang W; Department of Nephrology, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, Hubei, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Mar 15; Vol. 269, pp. 119017. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article
MeSH Terms :
Acute Kidney Injury/*genetics
Acute Kidney Injury/*pathology
Apoptosis Regulatory Proteins/*metabolism
Forkhead Box Protein O3/*metabolism
MicroRNAs/*metabolism
Sirtuin 1/*metabolism
Acetylation ; Animals ; Apoptosis ; Base Sequence ; Cell Line ; Cell Proliferation ; Down-Regulation/genetics ; Epithelial Cells/metabolism ; Epithelial-Mesenchymal Transition ; Fibrosis ; Gene Silencing ; Kidney Tubules/metabolism ; Kidney Tubules/pathology ; Male ; MicroRNAs/genetics ; Rats ; Rats, Sprague-Dawley ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
Kadsura heteroclita stem ethanol extract protects against carbon tetrachloride-induced liver injury in mice via suppression of oxidative stress, inflammation, and apoptosis.
Autorzy :
Yu HH; TCM and Ethnomedicine Innovation & Development International Laboratory, And Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan, 410208, PR China.
Qiu YX; TCM and Ethnomedicine Innovation & Development International Laboratory, And Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan, 410208, PR China.
Li B; TCM and Ethnomedicine Innovation & Development International Laboratory, And Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan, 410208, PR China.
Peng CY; TCM and Ethnomedicine Innovation & Development International Laboratory, And Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan, 410208, PR China.
Zeng R; TCM and Ethnomedicine Innovation & Development International Laboratory, And Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan, 410208, PR China. Electronic address: .
Wang W; TCM and Ethnomedicine Innovation & Development International Laboratory, And Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan, 410208, PR China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 01; Vol. 267, pp. 113496. Date of Electronic Publication: 2020 Oct 19.
Typ publikacji :
Journal Article
MeSH Terms :
Kadsura*/chemistry
Plant Stems*/chemistry
Anti-Inflammatory Agents/*pharmacology
Antioxidants/*pharmacology
Apoptosis/*drug effects
Chemical and Drug Induced Liver Injury/*prevention & control
Hepatocytes/*drug effects
Inflammation Mediators/*metabolism
Liver/*drug effects
Oxidative Stress/*drug effects
Animals ; Anti-Inflammatory Agents/isolation & purification ; Antioxidants/isolation & purification ; Apoptosis Regulatory Proteins/metabolism ; Biomarkers/blood ; Carbon Tetrachloride ; Chemical and Drug Induced Liver Injury/etiology ; Chemical and Drug Induced Liver Injury/metabolism ; Chemical and Drug Induced Liver Injury/pathology ; Disease Models, Animal ; Ethanol/chemistry ; Female ; Hepatocytes/metabolism ; Hepatocytes/pathology ; Liver/metabolism ; Liver/pathology ; Male ; Mice, Inbred ICR ; Necrosis ; Signal Transduction ; Solvents/chemistry
Czasopismo naukowe
Tytuł :
Cytotoxicity of botanicals and isolated phytochemicals from Araliopsis soyauxii Engl. (Rutaceae) towards a panel of human cancer cells.
Autorzy :
Mbaveng AT; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, University of Mainz, Staudinger Weg 5, 55128, Mainz, Germany; Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon. Electronic address: .
Noulala CGT; Department of Organic Chemistry, Faculty of Science, University of Yaoundé 1, Yaoundé, Cameroon. Electronic address: .
Samba ARM; Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon; Department of Organic Chemistry, Faculty of Science, University of Yaoundé 1, Yaoundé, Cameroon. Electronic address: .
Tankeo SB; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, University of Mainz, Staudinger Weg 5, 55128, Mainz, Germany; Department of Organic Chemistry, Faculty of Science, University of Yaoundé 1, Yaoundé, Cameroon. Electronic address: .
Fotso GW; Department of Organic Chemistry, Faculty of Science, University of Yaoundé 1, Yaoundé, Cameroon. Electronic address: .
Happi EN; Department of Chemistry, Faculty of Science, University of Douala, Douala, Cameroon. Electronic address: .
Ngadjui BT; Department of Organic Chemistry, Faculty of Science, University of Yaoundé 1, Yaoundé, Cameroon. Electronic address: .
Beng VP; Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon. Electronic address: .
Kuete V; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, University of Mainz, Staudinger Weg 5, 55128, Mainz, Germany; Department of Organic Chemistry, Faculty of Science, University of Yaoundé 1, Yaoundé, Cameroon. Electronic address: .
Efferth T; Department of Organic Chemistry, Faculty of Science, University of Yaoundé 1, Yaoundé, Cameroon. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 01; Vol. 267, pp. 113535. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Rutaceae*/chemistry
Antineoplastic Agents, Phytogenic/*pharmacology
Apoptosis/*drug effects
Neoplasms/*drug therapy
Phytochemicals/*pharmacology
Plant Extracts/*pharmacology
Antineoplastic Agents, Phytogenic/isolation & purification ; Apoptosis Regulatory Proteins/metabolism ; Benzoxepins/pharmacology ; Cell Cycle Checkpoints/drug effects ; Dose-Response Relationship, Drug ; HCT116 Cells ; Hep G2 Cells ; Humans ; Inhibitory Concentration 50 ; Limonins/pharmacology ; Membrane Potential, Mitochondrial/drug effects ; Mitochondria/drug effects ; Mitochondria/metabolism ; Mitochondria/pathology ; Neoplasms/pathology ; Oxidative Stress/drug effects ; Phytochemicals/isolation & purification ; Plant Extracts/isolation & purification ; Reactive Oxygen Species/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
BH3-only sensors Bad, Noxa and Puma are Key Regulators of Tacaribe virus-induced Apoptosis.
Autorzy :
Holzerland J; Junior Research Group Arenavirus Biology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald-Isle of Riems, Germany.
Fénéant L; Junior Research Group Arenavirus Biology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald-Isle of Riems, Germany.
Banadyga L; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.
Hölper JE; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald-Isle of Riems, Germany.
Knittler MR; Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald-Isle of Riems, Germany.
Groseth A; Junior Research Group Arenavirus Biology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald-Isle of Riems, Germany.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Oct 12; Vol. 16 (10), pp. e1008948. Date of Electronic Publication: 2020 Oct 12 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Virus Replication*
Apoptosis Regulatory Proteins/*metabolism
Arenaviridae Infections/*pathology
Arenaviruses, New World/*physiology
Proto-Oncogene Proteins/*metabolism
Proto-Oncogene Proteins c-bcl-2/*metabolism
bcl-Associated Death Protein/*metabolism
Apoptosis Regulatory Proteins/genetics ; Arenaviridae Infections/genetics ; Arenaviridae Infections/metabolism ; Arenaviridae Infections/virology ; Gene Expression Regulation ; Host-Pathogen Interactions ; Humans ; Protein Domains ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins c-bcl-2/genetics ; bcl-Associated Death Protein/genetics
Czasopismo naukowe
Tytuł :
Cadmium-induced Oxidative Stress and Immunosuppression Mediated Mitochondrial Apoptosis via JNK-FoxO3a-PUMA pathway in Common Carp (Cyprinus carpio L.) Gills.
Autorzy :
Chen J; College of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, China.
Chen D; College of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, China; College of Life Science and Technology, Southwest University for Nationalities, Chengdu, 610041, China.
Li J; College of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, China.
Liu Y; Heilongjiang Animal Husbandry Station, Harbin, 150069, China.
Gu X; Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100193, China. Electronic address: .
Teng X; College of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, China. Electronic address: .
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Źródło :
Aquatic toxicology (Amsterdam, Netherlands) [Aquat Toxicol] 2021 Apr; Vol. 233, pp. 105775. Date of Electronic Publication: 2021 Feb 13.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Cadmium/*toxicity
Carps/*metabolism
Gills/*drug effects
MAP Kinase Signaling System/*drug effects
Mitochondria/*drug effects
Oxidative Stress/*drug effects
Water Pollutants, Chemical/*toxicity
Animals ; Apoptosis Regulatory Proteins/metabolism ; Forkhead Transcription Factors/metabolism ; Gills/immunology ; Gills/metabolism ; Hydrogen Peroxide/metabolism ; Immune Tolerance/drug effects ; Mitochondria/metabolism ; Mitochondria/pathology ; Oxidative Stress/immunology ; Random Allocation
Czasopismo naukowe
Tytuł :
Silica nanoparticles induce mitochondrial pathway-dependent apoptosis by activating unfolded protein response in human neuroblastoma cells.
Autorzy :
Hou S; School of Public Health, Jilin University, Changchun, Jilin Province, China.
Zhang X; School of Public Health, Jilin University, Changchun, Jilin Province, China.
Du H; School of Public Health, Jilin University, Changchun, Jilin Province, China.
Ning X; School of Public Health, Jilin University, Changchun, Jilin Province, China.
Wu H; School of Public Health, Jilin University, Changchun, Jilin Province, China.
Li C; School of Public Health, Jilin University, Changchun, Jilin Province, China.
Liu Y; School of Public Health, Jilin University, Changchun, Jilin Province, China.
Sun Z; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, China.; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing, China.
Du Z; Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong Province, China.
Jin M; School of Public Health, Jilin University, Changchun, Jilin Province, China.
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Źródło :
Environmental toxicology [Environ Toxicol] 2021 Apr; Vol. 36 (4), pp. 675-685. Date of Electronic Publication: 2020 Dec 03.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Mitochondria/*drug effects
Nanoparticles/*toxicity
Silicon Dioxide/*toxicity
Unfolded Protein Response/*drug effects
Apoptosis Regulatory Proteins/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Humans ; Membrane Potential, Mitochondrial/drug effects ; Microscopy, Electron, Transmission ; Mitochondria/metabolism ; Nanoparticles/chemistry ; Neuroblastoma/metabolism ; Neuroblastoma/pathology ; Reactive Oxygen Species/metabolism ; Silicon Dioxide/chemistry
Czasopismo naukowe

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