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Wyszukujesz frazę ""arcuate nucleus"" wg kryterium: Temat


Tytuł :
Reduced food intake during exposure to high ambient temperatures is associated with molecular changes in the nucleus of the hippocampal commissure and the paraventricular and arcuate hypothalamic nuclei.
Autorzy :
Bohler M; Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, 2160 Litton-Reaves Hall, VA 24061, United States.
Gilbert ER; Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, 2160 Litton-Reaves Hall, VA 24061, United States.
Cline MA; Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, 2160 Litton-Reaves Hall, VA 24061, United States. Electronic address: .
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Źródło :
General and comparative endocrinology [Gen Comp Endocrinol] 2020 Nov 01; Vol. 298, pp. 113576. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji :
Journal Article
MeSH Terms :
Eating*/drug effects
Hot Temperature*
Arcuate Nucleus of Hypothalamus/*metabolism
Fornix, Brain/*metabolism
Paraventricular Hypothalamic Nucleus/*metabolism
Animals ; Anorexia/metabolism ; Arcuate Nucleus of Hypothalamus/drug effects ; Chickens/metabolism ; Corticotropin-Releasing Hormone/metabolism ; Corticotropin-Releasing Hormone/pharmacology ; Fornix, Brain/drug effects ; Injections, Intraventricular ; Male ; Neuropeptide Y/metabolism ; Peptide Fragments/pharmacology ; Proto-Oncogene Proteins c-fos/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; alpha-MSH/metabolism ; alpha-MSH/pharmacology
Czasopismo naukowe
Tytuł :
Organophosphate Flame Retardants Excite Arcuate Melanocortin Circuitry and Increase Neuronal Sensitivity to Ghrelin in Adult Mice.
Autorzy :
Vail GM; Joint Graduate Program in Toxicology, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Roepke TA; Joint Graduate Program in Toxicology, Rutgers, The State University of New Jersey, Piscataway, New Jersey.; Department of Animal Sciences, School of Environmental & Biological Sciences, Rutgers, The State University of New Jersey, New Brunswick, New Jersey.; Environmental and Occupational Health Science Institute, Rutgers, The State University of New Jersey, Piscataway, New Jersey.; Rutgers Center for Lipid Research, Center for Nutrition, Microbiome, and Health, and New Jersey Institute of Food, Nutrition, and Health, Rutgers, The State University of New Jersey, New Brunswick, New Jersey.
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Źródło :
Endocrinology [Endocrinology] 2020 Nov 01; Vol. 161 (11).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Arcuate Nucleus of Hypothalamus/*drug effects
Flame Retardants/*pharmacology
Ghrelin/*pharmacology
Melanocortins/*metabolism
Nerve Net/*drug effects
Neurons/*drug effects
Animals ; Arcuate Nucleus of Hypothalamus/metabolism ; Drug Resistance/drug effects ; Endocrine Disruptors/pharmacology ; Female ; Hypothalamus/metabolism ; Male ; Mice ; Mice, Transgenic ; Nerve Net/physiology ; Neurons/metabolism ; Neuropeptide Y/genetics ; Neuropeptide Y/metabolism ; Organophosphates/pharmacology ; Pro-Opiomelanocortin/genetics ; Pro-Opiomelanocortin/metabolism
Czasopismo naukowe
Tytuł :
Hypothalamic tanycytes generate acute hyperphagia through activation of the arcuate neuronal network.
Autorzy :
Bolborea M; School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom .
Pollatzek E; School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom.
Benford H; School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom.
Sotelo-Hitschfeld T; School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom.
Dale N; School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jun 23; Vol. 117 (25), pp. 14473-14481. Date of Electronic Publication: 2020 Jun 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arcuate Nucleus of Hypothalamus/*physiopathology
Ependymoglial Cells/*physiology
Hyperphagia/*physiopathology
Neurons/*physiology
Agouti-Related Protein/metabolism ; Animals ; Appetite/physiology ; Arcuate Nucleus of Hypothalamus/cytology ; Arcuate Nucleus of Hypothalamus/diagnostic imaging ; Channelrhodopsins/genetics ; Channelrhodopsins/metabolism ; Energy Metabolism/physiology ; Feeding Behavior/physiology ; Female ; Genes, Reporter ; Injections, Intraventricular ; Male ; Mice ; Mice, Transgenic ; Models, Animal ; Nerve Net/physiology ; Neuropeptide Y/metabolism ; Optical Imaging ; Optogenetics ; Patch-Clamp Techniques ; Pro-Opiomelanocortin/metabolism ; Stereotaxic Techniques
Czasopismo naukowe
Tytuł :
PNOC Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding.
Autorzy :
Jais A; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
Paeger L; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Institute for Zoology, Biocenter, University of Cologne, Cologne, Germany.
Sotelo-Hitschfeld T; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
Bremser S; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Institute for Zoology, Biocenter, University of Cologne, Cologne, Germany.
Prinzensteiner M; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
Klemm P; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
Mykytiuk V; Neuronal Circuits and Behaviour Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Widdershooven PJM; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
Vesting AJ; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany; Obesity and Cancer Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Grzelka K; Synaptic Transmission in Energy Homeostasis Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Minère M; Synaptic Transmission in Energy Homeostasis Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Cremer AL; Multimodal Imaging of Brain Metabolism Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Xu J; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Korotkova T; Neuronal Circuits and Behaviour Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Lowell BB; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA; Program in Neuroscience, Harvard Medical School, Boston, MA 02215, USA.
Zeilhofer HU; Institute of Pharmacology and Toxicology, University of Zurich, 8057 Zurich, Switzerland; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich, 8093 Zurich, Switzerland.
Backes H; Multimodal Imaging of Brain Metabolism Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Fenselau H; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Synaptic Transmission in Energy Homeostasis Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Wunderlich FT; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany; Obesity and Cancer Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.
Kloppenburg P; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Institute for Zoology, Biocenter, University of Cologne, Cologne, Germany. Electronic address: .
Brüning JC; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes, and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Jun 17; Vol. 106 (6), pp. 1009-1025.e10. Date of Electronic Publication: 2020 Apr 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diet, High-Fat*
Hyperphagia*
Obesity*
Arcuate Nucleus of Hypothalamus/*physiology
Feeding Behavior/*physiology
GABAergic Neurons/*physiology
Weight Gain/*physiology
Animals ; Arcuate Nucleus of Hypothalamus/cytology ; Arcuate Nucleus of Hypothalamus/metabolism ; GABAergic Neurons/metabolism ; Mice ; Neural Inhibition/physiology ; Neurons/metabolism ; Neurons/physiology ; Optogenetics ; Pro-Opiomelanocortin/metabolism ; Protein Precursors/metabolism ; Receptors, Opioid/metabolism ; Septal Nuclei/physiology
Czasopismo naukowe
Tytuł :
GABAergic input through GABA B receptors is necessary during a perinatal window to shape gene expression of factors critical to reproduction such as Kiss1 .
Autorzy :
Bizzozzero-Hiriart M; Laboratorio de Neuroendocrinología, Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.
Di Giorgio NP; Laboratorio de Neuroendocrinología, Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.
Libertun C; Laboratorio de Neuroendocrinología, Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.; Departamento de Fisiología, Facultad de Medicina, Universidad de Buenos Aires, Argentina.
Lux-Lantos V; Laboratorio de Neuroendocrinología, Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.
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Źródło :
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2020 Jun 01; Vol. 318 (6), pp. E901-E919. Date of Electronic Publication: 2020 Apr 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arcuate Nucleus of Hypothalamus/*metabolism
Gene Expression Regulation, Developmental/*physiology
Hypothalamus, Anterior/*metabolism
Receptors, GABA-B/*metabolism
Animals ; Animals, Newborn ; Arcuate Nucleus of Hypothalamus/drug effects ; Estradiol/metabolism ; Female ; Follicle Stimulating Hormone/metabolism ; GABA-B Receptor Antagonists/pharmacology ; Gene Expression Regulation, Developmental/drug effects ; Glutamate Decarboxylase/genetics ; Glutamate Decarboxylase/metabolism ; Gonadotropin-Releasing Hormone/genetics ; Gonadotropin-Releasing Hormone/metabolism ; Hypothalamus, Anterior/drug effects ; Kisspeptins/genetics ; Kisspeptins/metabolism ; Luteinizing Hormone/metabolism ; Male ; Mice ; Ovary/drug effects ; Ovary/metabolism ; Phosphinic Acids/pharmacology ; Propanolamines/pharmacology ; Protein Precursors/genetics ; Protein Precursors/metabolism ; Puberty/drug effects ; Puberty/genetics ; Receptors, Estrogen/genetics ; Receptors, Estrogen/metabolism ; Receptors, GABA-B/genetics ; Receptors, Progesterone/genetics ; Receptors, Progesterone/metabolism ; Reproduction/drug effects ; Reproduction/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Sex Differentiation/drug effects ; Sex Differentiation/genetics ; Tachykinins/genetics ; Tachykinins/metabolism ; Testis/drug effects ; Testis/metabolism ; Testosterone/metabolism ; Tyrosine 3-Monooxygenase/genetics ; Tyrosine 3-Monooxygenase/metabolism
Czasopismo naukowe
Tytuł :
Decoding neuronal composition and ontogeny of individual hypothalamic nuclei.
Autorzy :
Ma T; Department of Neuroscience and Mahoney Institute for Neurosciences, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Wong SZH; Department of Neuroscience and Mahoney Institute for Neurosciences, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; The Cellular and Molecular Medicine Graduate Program, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Lee B; Center for Neuroscience, Korea Institute of Science and Technology, Seoul 02792, Korea.
Ming GL; Department of Neuroscience and Mahoney Institute for Neurosciences, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Song H; Department of Neuroscience and Mahoney Institute for Neurosciences, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; The Epigenetic Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2021 Apr 07; Vol. 109 (7), pp. 1150-1167.e6. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Hypothalamus/*cytology
Hypothalamus/*growth & development
Neurons/*physiology
Animals ; Animals, Genetically Modified ; Arcuate Nucleus of Hypothalamus/cytology ; Arcuate Nucleus of Hypothalamus/embryology ; Cell Lineage ; Glutamic Acid/physiology ; Homeodomain Proteins/metabolism ; Hypothalamus/embryology ; Mice ; Mice, Inbred C57BL ; Nerve Tissue Proteins/metabolism ; Neuroglia/physiology ; Stem Cells/physiology ; T-Box Domain Proteins/metabolism ; Transcription Factors/metabolism ; Ventromedial Hypothalamic Nucleus/cytology ; Ventromedial Hypothalamic Nucleus/embryology ; Ventromedial Hypothalamic Nucleus/metabolism ; gamma-Aminobutyric Acid/physiology
Czasopismo naukowe
Tytuł :
Prepubertal exposure to high dose of cadmium induces hypothalamic injury through transcriptome profiling alteration and neuronal degeneration in female rats.
Autorzy :
Saedi S; Department of Animal Science, College of Agriculture, Shiraz University, Shiraz, Iran.
Jafarzadeh Shirazi MR; Department of Animal Science, College of Agriculture, Shiraz University, Shiraz, Iran. Electronic address: .
Niazi A; Biotechnology Institute, College of Agriculture Shiraz University Shiraz, Iran.
Tahmasebi A; Biotechnology Institute, College of Agriculture Shiraz University Shiraz, Iran.
Ebrahimie E; Division of Information Technology, Engineering and the Environment, School of Information Technology and Mathematical Sciences, University of South Australia, Adelaide, SA, Australia; School of Biological Sciences, Faculty of Science and Engineering, Flinders University, Adelaide, Australia.
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 Mar 01; Vol. 337, pp. 109379. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article
MeSH Terms :
Cadmium Chloride/*toxicity
Hypothalamus/*drug effects
Transcriptome/*drug effects
Animals ; Arcuate Nucleus of Hypothalamus/drug effects ; Arcuate Nucleus of Hypothalamus/metabolism ; Arcuate Nucleus of Hypothalamus/pathology ; Blood Glucose/analysis ; Down-Regulation/drug effects ; Female ; Gene Ontology ; Gene Regulatory Networks/drug effects ; Hypothalamus/metabolism ; Hypothalamus/pathology ; Immune System/drug effects ; Immune System/metabolism ; Neuropeptides/genetics ; Neuropeptides/metabolism ; Prolactin/blood ; Rats ; Rats, Sprague-Dawley ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
GnRH(1-5), a metabolite of gonadotropin-releasing hormone, enhances luteinizing hormone release via activation of kisspeptin neurons in female rats.
Autorzy :
Ieda N; Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
Assadullah; Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
Minabe S; Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
Ikegami K; Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
Watanabe Y; Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
Sugimoto Y; Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
Sugimoto A; Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
Kawai N; Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
Ishii H; Department of Anatomy and Neurobiology, Nippon Medical School, Tokyo 113-8602, Japan.
Inoue N; Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
Uenoyama Y; Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
Tsukamura H; Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
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Źródło :
Endocrine journal [Endocr J] 2020 Apr 28; Vol. 67 (4), pp. 409-418. Date of Electronic Publication: 2020 Jan 15.
Typ publikacji :
Journal Article
MeSH Terms :
Arcuate Nucleus of Hypothalamus/*drug effects
Gonadotropin-Releasing Hormone/*pharmacology
Hypothalamus, Anterior/*drug effects
Kisspeptins/*genetics
Luteinizing Hormone/*drug effects
Neurons/*metabolism
Peptide Fragments/*pharmacology
Animals ; Arcuate Nucleus of Hypothalamus/cytology ; Arcuate Nucleus of Hypothalamus/metabolism ; Estradiol/pharmacology ; Estrogens/pharmacology ; Female ; Gene Knockout Techniques ; Hypothalamus, Anterior/cytology ; Hypothalamus, Anterior/metabolism ; In Situ Hybridization ; Injections, Intraventricular ; Kisspeptins/pharmacology ; Luteinizing Hormone/metabolism ; Nerve Tissue Proteins/genetics ; Ovariectomy ; Rats ; Rats, Transgenic ; Receptors, G-Protein-Coupled/genetics ; Receptors, N-Methyl-D-Aspartate/genetics ; Vesicular Glutamate Transport Protein 2/genetics
Czasopismo naukowe
Tytuł :
Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice.
Autorzy :
Zakariassen HL; Section of Experimental Animal Models, Department of Veterinary and Animal Science, Faculty of Health and Medical Sciences, University of Copenhagen, DK-1871, Frederiksberg C, Denmark; Obesity Pharmacology, Novo Nordisk A/S, 2760, Måløv, Denmark.
John LM; Obesity Pharmacology, Novo Nordisk A/S, 2760, Måløv, Denmark.
Lykkesfeldt J; Section of Experimental Animal Models, Department of Veterinary and Animal Science, Faculty of Health and Medical Sciences, University of Copenhagen, DK-1871, Frederiksberg C, Denmark.
Raun K; Obesity Pharmacology, Novo Nordisk A/S, 2760, Måløv, Denmark.
Glendorf T; Diabetes Pharmacology 2, Novo Nordisk A/S, 2760, Måløv, Denmark.
Schaffer L; Research Chemistry, Novo Nordisk A/S, 2760, Måløv, Denmark.
Lundh S; Pathology and Imaging, Novo Nordisk A/S, 2760, Måløv, Denmark.
Secher A; Diabetes Pharmacology 2, Novo Nordisk A/S, 2760, Måløv, Denmark.
Lutz TA; Institute of Veterinary Physiology, University of Zurich, CH-8057, Zurich, Switzerland.
Le Foll C; Institute of Veterinary Physiology, University of Zurich, CH-8057, Zurich, Switzerland. Electronic address: .
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Źródło :
Neuropharmacology [Neuropharmacology] 2020 May 01; Vol. 167, pp. 107987. Date of Electronic Publication: 2020 Feb 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arcuate Nucleus of Hypothalamus/*metabolism
Calcitonin/*metabolism
Calcium-Regulating Hormones and Agents/*metabolism
Neurons/*metabolism
Neuropeptide Y/*metabolism
Animals ; Arcuate Nucleus of Hypothalamus/drug effects ; Calcitonin/administration & dosage ; Calcium-Regulating Hormones and Agents/administration & dosage ; Cell Line ; Cricetinae ; Female ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Neurons/drug effects ; Protein Binding/physiology ; Rats
Czasopismo naukowe
Tytuł :
Exploration of cardiometabolic and developmental significance of angiotensinogen expression by cells expressing the leptin receptor or agouti-related peptide.
Autorzy :
Sapouckey SA; Department of Neuroscience and Pharmacology, University of Iowa, Iowa City, Iowa.
Morselli LL; Division of Endocrinology, Department of Internal Medicine, University of Iowa, Iowa City, Iowa.
Deng G; Department of Neuroscience and Pharmacology, University of Iowa, Iowa City, Iowa.
Patil CN; Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Balapattabi K; Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Oliveira V; Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Claflin KE; Department of Neuroscience and Pharmacology, University of Iowa, Iowa City, Iowa.
Gomez J; Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Pearson NA; Department of Neuroscience and Pharmacology, University of Iowa, Iowa City, Iowa.
Potthoff MJ; Department of Neuroscience and Pharmacology, University of Iowa, Iowa City, Iowa.; Obesity Research & Education Initiative, University of Iowa, Iowa City, Iowa.; Fraternal Order of Eagles' Diabetes Research Center, University of Iowa, Iowa City, Iowa.
Gibson-Corley KN; Fraternal Order of Eagles' Diabetes Research Center, University of Iowa, Iowa City, Iowa.; Department of Pathology, University of Iowa, Iowa City, Iowa.
Sigmund CD; Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, Wisconsin.; Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
Grobe JL; Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, Wisconsin.; Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin.; Department of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, Wisconsin.; Comprehensive Rodent Metabolic Phenotyping Core, Medical College of Wisconsin, Milwaukee, Wisconsin.
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Źródło :
American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2020 May 01; Vol. 318 (5), pp. R855-R869. Date of Electronic Publication: 2020 Mar 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Energy Metabolism*
Adrenal Glands/*metabolism
Agouti-Related Protein/*metabolism
Angiotensinogen/*metabolism
Arcuate Nucleus of Hypothalamus/*metabolism
Kidney/*metabolism
Receptors, Leptin/*metabolism
Adrenal Glands/growth & development ; Agouti-Related Protein/deficiency ; Agouti-Related Protein/genetics ; Angiotensinogen/deficiency ; Angiotensinogen/genetics ; Animals ; Arcuate Nucleus of Hypothalamus/growth & development ; Autocrine Communication ; Female ; Gene Expression Regulation, Developmental ; Kidney/growth & development ; Male ; Mice, Knockout ; Myocardium/metabolism ; Paracrine Communication ; Receptors, Leptin/deficiency ; Receptors, Leptin/genetics ; Serum Albumin/genetics ; Serum Albumin/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Retinoblastoma binding protein 7 is involved in Kiss1 mRNA upregulation in rodents.
Autorzy :
Horihata K; Laboratory of Animal Reproduction, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
Inoue N; Laboratory of Animal Reproduction, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
Uenoyama Y; Laboratory of Animal Reproduction, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
Maeda KI; Laboratory of Theriogenology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.
Tsukamura H; Laboratory of Animal Reproduction, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
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Źródło :
The Journal of reproduction and development [J Reprod Dev] 2020 Apr 10; Vol. 66 (2), pp. 125-133. Date of Electronic Publication: 2020 Jan 19.
Typ publikacji :
Journal Article
MeSH Terms :
Up-Regulation*
Arcuate Nucleus of Hypothalamus/*metabolism
Hypothalamus, Anterior/*metabolism
Kisspeptins/*metabolism
Retinoblastoma-Binding Protein 7/*metabolism
Animals ; Arcuate Nucleus of Hypothalamus/drug effects ; Cell Line ; Estradiol/pharmacology ; Female ; Hypothalamus, Anterior/drug effects ; Kisspeptins/genetics ; Neurons/drug effects ; Neurons/metabolism ; Rats ; Retinoblastoma-Binding Protein 7/genetics
Czasopismo naukowe
Tytuł :
Expression of a hypomorphic Pomc allele alters leptin dynamics during late pregnancy.
Autorzy :
Yu H; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Thompson Z; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Kiran S; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; School of Literature, Science, and Arts, University of Michigan, Ann Arbor, Michigan, USA.
Jones GL; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Neuroscience Graduate Program, University of Michigan, Ann Arbor, Michigan, USA.
Mundada L; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Rubinstein M; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Instituto de Investigaciones en Ingeniería Genética y Biología Molecular Consejo Nacional de Investigaciones Científicas y Técnicas and Facultad de Ciencias Exactas y Naturales, Universidad de Buenos, Buenos Aires, Argentina.
Low MJ; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
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Corporate Authors :
Surbhi; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Źródło :
The Journal of endocrinology [J Endocrinol] 2020 Apr; Vol. 245 (1), pp. 115-127.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Gene Expression Regulation, Developmental*
Arcuate Nucleus of Hypothalamus/*metabolism
Leptin/*metabolism
Neurons/*metabolism
Pro-Opiomelanocortin/*genetics
Adiposity/genetics ; Alleles ; Animals ; Arcuate Nucleus of Hypothalamus/cytology ; Body Weight ; Female ; Leptin/blood ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Placenta/embryology ; Placenta/metabolism ; Pregnancy ; Pro-Opiomelanocortin/metabolism ; Receptors, Leptin/genetics ; Receptors, Leptin/metabolism
Czasopismo naukowe
Tytuł :
Insulin-induced hypoglycaemia suppresses pulsatile luteinising hormone secretion and arcuate Kiss1 cell activation in female mice.
Autorzy :
McCosh RB; Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Diego, CA, USA.
Kreisman MJ; Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Diego, CA, USA.
Tian K; Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Diego, CA, USA.
Ho BS; Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Diego, CA, USA.
Thackray VG; Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Diego, CA, USA.
Breen KM; Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Diego, CA, USA.
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Źródło :
Journal of neuroendocrinology [J Neuroendocrinol] 2019 Dec; Vol. 31 (12), pp. e12813. Date of Electronic Publication: 2019 Dec 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Arcuate Nucleus of Hypothalamus/*physiology
Hypoglycemia/*physiopathology
Insulins/*pharmacology
Kisspeptins/*physiology
Luteinizing Hormone/*metabolism
Animals ; Arcuate Nucleus of Hypothalamus/drug effects ; Arcuate Nucleus of Hypothalamus/metabolism ; Fasting ; Female ; Hypoglycemia/chemically induced ; Hypoglycemia/metabolism ; Kisspeptins/genetics ; Kisspeptins/pharmacology ; Mice ; Mice, Transgenic ; Neurons/drug effects ; Neurons/metabolism ; Neurons/physiology ; Ovariectomy ; Proto-Oncogene Proteins c-fos/metabolism
Czasopismo naukowe
Tytuł :
Regulation of the firing activity by PKA-PKC-Src family kinases in cultured neurons of hypothalamic arcuate nucleus.
Autorzy :
Sun XD; Key Laboratory of Pain Basic Research and Clinical Therapy, Department of Physiology and Neurobiology, Medical College of Soochow University, Suzhou, China.
Wang A; Key Laboratory of Pain Basic Research and Clinical Therapy, Department of Physiology and Neurobiology, Medical College of Soochow University, Suzhou, China.
Ma P; Key Laboratory of Pain Basic Research and Clinical Therapy, Department of Physiology and Neurobiology, Medical College of Soochow University, Suzhou, China.
Gong S; Key Laboratory of Pain Basic Research and Clinical Therapy, Department of Physiology and Neurobiology, Medical College of Soochow University, Suzhou, China.
Tao J; Key Laboratory of Pain Basic Research and Clinical Therapy, Department of Physiology and Neurobiology, Medical College of Soochow University, Suzhou, China.
Yu XM; Key Laboratory of Pain Basic Research and Clinical Therapy, Department of Physiology and Neurobiology, Medical College of Soochow University, Suzhou, China.
Jiang X; Key Laboratory of Pain Basic Research and Clinical Therapy, Department of Physiology and Neurobiology, Medical College of Soochow University, Suzhou, China.
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Źródło :
Journal of neuroscience research [J Neurosci Res] 2020 Feb; Vol. 98 (2), pp. 384-403. Date of Electronic Publication: 2019 Aug 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Action Potentials/*physiology
Arcuate Nucleus of Hypothalamus/*metabolism
Cyclic AMP-Dependent Protein Kinases/*metabolism
Neurons/*metabolism
Protein Kinase C/*metabolism
src-Family Kinases/*metabolism
Action Potentials/drug effects ; Animals ; Arcuate Nucleus of Hypothalamus/drug effects ; Cells, Cultured ; Colforsin/pharmacology ; Female ; Male ; Neurons/drug effects ; Oligopeptides/pharmacology ; Patch-Clamp Techniques ; Phosphorylation/drug effects ; Rats ; Rats, Sprague-Dawley ; Vasodilator Agents/pharmacology
Czasopismo naukowe
Tytuł :
Neurochemical Characterization of Neurons Expressing Estrogen Receptor β in the Hypothalamic Nuclei of Rats Using in Situ Hybridization and Immunofluorescence.
Autorzy :
Kanaya M; Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.
Higo S; Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.
Ozawa H; Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2019 Dec 23; Vol. 21 (1). Date of Electronic Publication: 2019 Dec 23.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation*
Arcuate Nucleus of Hypothalamus/*metabolism
Estrogen Receptor beta/*biosynthesis
Neurons/*metabolism
Paraventricular Hypothalamic Nucleus/*metabolism
Animals ; Arcuate Nucleus of Hypothalamus/cytology ; Arginine Vasopressin/biosynthesis ; Female ; Fluorescent Antibody Technique ; In Situ Hybridization ; Male ; Neurons/cytology ; Paraventricular Hypothalamic Nucleus/cytology ; Rats
Czasopismo naukowe
Tytuł :
Stimulation of 5-HT 2C serotonin receptor subtype in the hypothalamic arcuate nuclei (ARC) increases the cytochrome P450 activity in the liver.
Autorzy :
Bromek E; Maj Institute of Pharmacology, Department of Pharmacokinetics and Drug Metabolism, Polish Academy of Sciences, Kraków, Poland.
Rysz M; Maj Institute of Pharmacology, Department of Pharmacokinetics and Drug Metabolism, Polish Academy of Sciences, Kraków, Poland.
Haduch A; Maj Institute of Pharmacology, Department of Pharmacokinetics and Drug Metabolism, Polish Academy of Sciences, Kraków, Poland.
Daniel WA; Maj Institute of Pharmacology, Department of Pharmacokinetics and Drug Metabolism, Polish Academy of Sciences, Kraków, Poland. Electronic address: .
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Źródło :
Pharmacological reports : PR [Pharmacol Rep] 2019 Dec; Vol. 71 (6), pp. 1210-1212. Date of Electronic Publication: 2019 May 17.
Typ publikacji :
Journal Article
MeSH Terms :
Arcuate Nucleus of Hypothalamus/*metabolism
Liver/*metabolism
Receptor, Serotonin, 5-HT2C/*metabolism
Receptors, Serotonin/*metabolism
Serotonin/*metabolism
Animals ; Arcuate Nucleus of Hypothalamus/drug effects ; Cytochrome P-450 Enzyme System/metabolism ; Liver/drug effects ; Male ; Neurosecretory Systems/drug effects ; Neurosecretory Systems/metabolism ; Piperazines/pharmacology ; Pyrazines/pharmacology ; Rats ; Rats, Wistar ; Serotonin Receptor Agonists/pharmacology
Czasopismo naukowe
Tytuł :
Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production.
Autorzy :
Kwon E; The Fleischer Institute for Diabetes and Metabolism, Albert Einstein College of Medicine, Bronx, NY, USA.; Division of Endocrinology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.
Joung HY; The Fleischer Institute for Diabetes and Metabolism, Albert Einstein College of Medicine, Bronx, NY, USA.; Division of Endocrinology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.
Liu SM; The Fleischer Institute for Diabetes and Metabolism, Albert Einstein College of Medicine, Bronx, NY, USA.; Division of Endocrinology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.
Chua SC Jr; The Fleischer Institute for Diabetes and Metabolism, Albert Einstein College of Medicine, Bronx, NY, USA.; Division of Endocrinology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.
Schwartz GJ; The Fleischer Institute for Diabetes and Metabolism, Albert Einstein College of Medicine, Bronx, NY, USA.; Division of Endocrinology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.
Jo YH; The Fleischer Institute for Diabetes and Metabolism, Albert Einstein College of Medicine, Bronx, NY, USA. .; Division of Endocrinology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA. .; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Dec 08; Vol. 11 (1), pp. 6295. Date of Electronic Publication: 2020 Dec 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Glucose/*metabolism
Hypoglycemia/*etiology
Liver/*innervation
Pro-Opiomelanocortin/*metabolism
Vagus Nerve/*metabolism
Acetylcholine/metabolism ; Action Potentials/physiology ; Animals ; Arcuate Nucleus of Hypothalamus/cytology ; Arcuate Nucleus of Hypothalamus/metabolism ; Blood Glucose/analysis ; Cholinergic Neurons/metabolism ; Corticosterone/blood ; Corticosterone/metabolism ; Disease Models, Animal ; Efferent Pathways/physiology ; Female ; Gene Knockdown Techniques ; Glucagon/blood ; Glucagon/metabolism ; Gluconeogenesis/genetics ; Humans ; Hypoglycemia/blood ; Hypoglycemia/diagnosis ; Insulin/blood ; Insulin/metabolism ; Liver/enzymology ; Male ; Mice ; Optogenetics ; RNA, Messenger/metabolism ; Receptor, Melanocortin, Type 4/antagonists & inhibitors ; Receptor, Melanocortin, Type 4/genetics ; Receptor, Melanocortin, Type 4/metabolism ; Up-Regulation ; Vagus Nerve/cytology
Czasopismo naukowe
Tytuł :
Cafeteria diet induces progressive changes in hypothalamic mechanisms involved in food intake control at different feeding periods in female rats.
Autorzy :
Lazzarino GP; Instituto de Salud y Ambiente Del Litoral (ISAL), Universidad Nacional Del Litoral - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Facultad de Bioquímica y Ciencias Biológicas, Ciudad Universitaria, Paraje El Pozo S/N, S3000, Santa Fe, Argentina. Electronic address: .
Acutain MF; Instituto de Salud y Ambiente Del Litoral (ISAL), Universidad Nacional Del Litoral - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Facultad de Bioquímica y Ciencias Biológicas, Ciudad Universitaria, Paraje El Pozo S/N, S3000, Santa Fe, Argentina. Electronic address: .
Canesini G; Instituto de Salud y Ambiente Del Litoral (ISAL), Universidad Nacional Del Litoral - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Facultad de Bioquímica y Ciencias Biológicas, Ciudad Universitaria, Paraje El Pozo S/N, S3000, Santa Fe, Argentina; Cátedra de Patología Humana, Facultad de Bioquímica y Ciencias Biológicas (FBCB), Universidad Nacional Del Litoral (UNL), Ciudad Universitaria, Paraje El Pozo S/N, S3000, Santa Fe, Argentina. Electronic address: .
Andreoli MF; Instituto de Salud y Ambiente Del Litoral (ISAL), Universidad Nacional Del Litoral - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Facultad de Bioquímica y Ciencias Biológicas, Ciudad Universitaria, Paraje El Pozo S/N, S3000, Santa Fe, Argentina. Electronic address: .
Ramos JG; Departamento de Bioquímica Clínica y Cuantitativa, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional Del Litoral, Ciudad Universitaria, Paraje El Pozo S/N, S3000, Santa Fe, Argentina; Instituto de Salud y Ambiente Del Litoral (ISAL), Universidad Nacional Del Litoral - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Facultad de Bioquímica y Ciencias Biológicas, Ciudad Universitaria, Paraje El Pozo S/N, S3000, Santa Fe, Argentina. Electronic address: .
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Źródło :
Molecular and cellular endocrinology [Mol Cell Endocrinol] 2019 Dec 01; Vol. 498, pp. 110542. Date of Electronic Publication: 2019 Aug 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adiposity*
Feeding Behavior*
Arcuate Nucleus of Hypothalamus/*pathology
Diet/*adverse effects
Hypothalamus/*pathology
Obesity/*etiology
Agouti-Related Protein/genetics ; Agouti-Related Protein/metabolism ; Animals ; Arcuate Nucleus of Hypothalamus/metabolism ; Body Weight ; DNA Methylation ; Energy Metabolism ; Female ; Gene Expression Regulation ; Hypothalamus/metabolism ; Neuropeptides/genetics ; Neuropeptides/metabolism ; Nutrients/analysis ; Obesity/metabolism ; Obesity/pathology ; Orexins/genetics ; Orexins/metabolism ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Acupuncture attenuates alcohol dependence through activation of endorphinergic input to the nucleus accumbens from the arcuate nucleus.
Autorzy :
Chang S; College of Korean Medicine, Daegu Haany University, Daegu 42158, Republic of Korea.
Kim DH; College of Korean Medicine, Daegu Haany University, Daegu 42158, Republic of Korea.
Jang EY; College of Korean Medicine, Daegu Haany University, Daegu 42158, Republic of Korea.
Yoon SS; College of Korean Medicine, Daegu Haany University, Daegu 42158, Republic of Korea.
Gwak YS; Department of Anesthesiology, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA.
Yi YJ; College of Korean Medicine, Daegu Haany University, Daegu 42158, Republic of Korea.
Lee JY; College of Korean Medicine, Daegu Haany University, Daegu 42158, Republic of Korea.
Ahn SH; College of Korean Medicine, Daegu Haany University, Daegu 42158, Republic of Korea.
Kim JM; College of Korean Medicine, Daegu Haany University, Daegu 42158, Republic of Korea.
Ryu YH; Acupuncture, Moxibustion & Meridian Research Center, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.
Kim SN; College of Korean Medicine, Dongguk University, Goyang 10326, Republic of Korea.
Roh HS; College of Korean Medicine, Dongguk University, Goyang 10326, Republic of Korea.
Lee MY; College of Biomedical Science, Daegu Haany University, Gyeongbuk 38610, Republic of Korea.
Kim SC; College of Korean Medicine, Daegu Haany University, Daegu 42158, Republic of Korea.
Lee BH; College of Korean Medicine, Daegu Haany University, Daegu 42158, Republic of Korea.
Kim HY; College of Korean Medicine, Daegu Haany University, Daegu 42158, Republic of Korea.
Yang CH; College of Korean Medicine, Daegu Haany University, Daegu 42158, Republic of Korea.
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Źródło :
Science advances [Sci Adv] 2019 Sep 04; Vol. 5 (9), pp. eaax1342. Date of Electronic Publication: 2019 Sep 04 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acupuncture Therapy*
Alcoholism*/metabolism
Alcoholism*/pathology
Alcoholism*/therapy
Arcuate Nucleus of Hypothalamus*/metabolism
Arcuate Nucleus of Hypothalamus*/pathology
Nucleus Accumbens*/metabolism
Nucleus Accumbens*/pathology
Substance Withdrawal Syndrome*/metabolism
Substance Withdrawal Syndrome*/pathology
Substance Withdrawal Syndrome*/therapy
beta-Endorphin/*metabolism
Animals ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Nitric oxide resets kisspeptin-excited GnRH neurons via PIP2 replenishment.
Autorzy :
Constantin S; Cellular and Developmental Neurobiology Section, National Institute of Neurological Disorders and Stroke (NINDS), NIH, Bethesda, MD 20892.
Reynolds D; Cellular and Developmental Neurobiology Section, National Institute of Neurological Disorders and Stroke (NINDS), NIH, Bethesda, MD 20892.
Oh A; Cellular and Developmental Neurobiology Section, National Institute of Neurological Disorders and Stroke (NINDS), NIH, Bethesda, MD 20892.
Pizano K; Cellular and Developmental Neurobiology Section, National Institute of Neurological Disorders and Stroke (NINDS), NIH, Bethesda, MD 20892.
Wray S; Cellular and Developmental Neurobiology Section, National Institute of Neurological Disorders and Stroke (NINDS), NIH, Bethesda, MD 20892 .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jan 05; Vol. 118 (1).
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
Calcium Signaling/*physiology
Gonadotropin-Releasing Hormone/*metabolism
Neurons/*metabolism
Animals ; Arcuate Nucleus of Hypothalamus/metabolism ; Calcium/metabolism ; Calcium Channels/metabolism ; Female ; Hypothalamus/metabolism ; Kisspeptins/metabolism ; Luteinizing Hormone/metabolism ; Male ; Mice ; Nitric Oxide/metabolism ; Phosphatidylinositol 4,5-Diphosphate/metabolism ; Phosphatidylinositol 4,5-Diphosphate/physiology ; Primary Cell Culture/methods
Czasopismo naukowe

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