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Tytuł:
Implications of Peptidyl Arginine Deiminase 4 gene transcription and polymorphisms in susceptibility to rheumatoid arthritis in an Iranian population.
Autorzy:
Bagheri-Hosseinabadi Z; Molecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.; Department of Clinical Biochemistry, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Mirzaei MR; Molecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Esmaeili O; Department of Clinical Biochemistry, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Asadi F; Molecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Ahmadinia H; Occupational Environmental Research Center, Medical School, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Shamsoddini B; Student Research Committee, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Abbasifard M; Molecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. .; Department of Internal Medicine, Ali-Ibn Abi-Talib Hospital, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. .
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Źródło:
BMC medical genomics [BMC Med Genomics] 2023 May 16; Vol. 16 (1), pp. 104. Date of Electronic Publication: 2023 May 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Arthritis, Rheumatoid*/genetics
Genetic Predisposition to Disease*
Protein-Arginine Deiminase Type 4*/genetics
Humans ; Genotype ; Iran ; Polymorphism, Single Nucleotide ; Transcription, Genetic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The strain-dependent cytostatic activity of Lactococcus lactis on CRC cell lines is mediated through the release of arginine deiminase.
Autorzy:
Jastrząb, Rafał (AUTHOR)
Tomecki, Rafał (AUTHOR)
Jurkiewicz, Aneta (AUTHOR)
Graczyk, Damian (AUTHOR)
Szczepankowska, Agnieszka K. (AUTHOR)
Mytych, Jennifer (AUTHOR)
Wolman, Damian (AUTHOR)
Siedlecki, Pawel (AUTHOR)
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Źródło:
Microbial Cell Factories. 3/13/2024, Vol. 23 Issue 1, p1-20. 20p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
4-(Phenylselanyl)-2H-chromen-2-one-Loaded Nanocapsule Suspension—A Promising Breakthrough in Pain Management: Comprehensive Molecular Docking, Formulation Design, and Toxicological and Pharmacological Assessments in Mice.
Autorzy:
da Fonseca, Caren Aline Ramson (AUTHOR)
Prado, Vinicius Costa (AUTHOR)
Paltian, Jaini Janke (AUTHOR)
Kazmierczak, Jean Carlo (AUTHOR)
Schumacher, Ricardo Frederico (AUTHOR)
Sari, Marcel Henrique Marcondes (AUTHOR)
Cordeiro, Larissa Marafiga (AUTHOR)
da Silva, Aline Franzen (AUTHOR)
Soares, Felix Alexandre Antunes (AUTHOR)
Oliboni, Robson da Silva (AUTHOR)
Luchese, Cristiane (AUTHOR)
Cruz, Letícia (AUTHOR)
Wilhelm, Ethel Antunes (AUTHOR)
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Źródło:
Pharmaceutics. Feb2024, Vol. 16 Issue 2, p269. 26p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Atractylenolide II Suppresses Glycolysis and Induces Apoptosis by Blocking the PADI3-ERK Signaling Pathway in Endometrial Cancer Cells.
Autorzy:
Tian S; Department of Pathology, College of Integrated Chinese and Western Medical, Liaoning University of Traditional Chinese Medicine, Shenyang 110847, China.; Department of Cell Biology and Genetics, Basic Medical College, Jinzhou Medical University, Jinzhou 121001, China.
Ren L; Department of Neurobiology, Basic Medical College, Jinzhou Medical University, Jinzhou 121001, China.
Liu C; Department of Cell Biology and Genetics, Basic Medical College, Jinzhou Medical University, Jinzhou 121001, China.
Wang Z; Department of Pathology, College of Integrated Chinese and Western Medical, Liaoning University of Traditional Chinese Medicine, Shenyang 110847, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 21; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:
Journal Article
MeSH Terms:
Signal Transduction*
Endometrial Neoplasms*/drug therapy
Lactones*
Sesquiterpenes*
Female ; Humans ; Apoptosis ; Cell Proliferation ; Apoptosis Regulatory Proteins/metabolism ; Glycolysis ; Cell Line, Tumor ; Protein-Arginine Deiminase Type 3/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Alleviation of arthritis through prevention of neutrophil extracellular traps by an orally available inhibitor of protein arginine deiminase 4.
Autorzy:
Gajendran C; Jubilant Therapeutics Inc., Bedminster, NJ, USA.
Fukui S; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA.
Sadhu NM; Jubilant Therapeutics Inc., Bedminster, NJ, USA.
Zainuddin M; Jubilant Therapeutics Inc., Bedminster, NJ, USA.
Rajagopal S; Jubilant Therapeutics Inc., Bedminster, NJ, USA.
Gosu R; Jubilant Therapeutics Inc., Bedminster, NJ, USA.
Gutch S; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.
Fukui S; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.
Sheehy CE; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.
Chu L; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.
Vishwakarma S; Jubilant Biosys Limited, Bangalore, India.
Jeyaraj DA; Jubilant Biosys Limited, Bangalore, India.
Hallur G; Jubilant Biosys Limited, Bangalore, India.
Wagner DD; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02125, USA.
Sivanandhan D; Jubilant Therapeutics Inc., Bedminster, NJ, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Feb 23; Vol. 13 (1), pp. 3189. Date of Electronic Publication: 2023 Feb 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Arthritis, Rheumatoid*/metabolism
Extracellular Traps*/metabolism
Protein-Arginine Deiminase Type 4*/antagonists & inhibitors
Animals ; Humans ; Mice ; Mice, Knockout ; Neutrophils/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Peptidylarginine Deiminase Inhibitor Application, Using Cl-Amidine, PAD2, PAD3 and PAD4 Isozyme-Specific Inhibitors in Pancreatic Cancer Cells, Reveals Roles for PAD2 and PAD3 in Cancer Invasion and Modulation of Extracellular Vesicle Signatures.
Autorzy:
Uysal-Onganer P; Cancer Research Group, School of Life Sciences, University of Westminster, London W1W 6 UW, UK.
D'Alessio S; Tissue Architecture and Regeneration Research Group, School of Life Sciences, University of Westminster, London W1W 6 UW, UK.
Mortoglou M; Cancer Research Group, School of Life Sciences, University of Westminster, London W1W 6 UW, UK.
Kraev I; Electron Microscopy Suite, Faculty of Science, Technology, Engineering and Mathematics, Open University, Milton Keynes MK7 6AA, UK.
Lange S; Tissue Architecture and Regeneration Research Group, School of Life Sciences, University of Westminster, London W1W 6 UW, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 30; Vol. 22 (3). Date of Electronic Publication: 2021 Jan 30.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Pancreatic Ductal/*pathology
Extracellular Vesicles/*metabolism
Pancreatic Neoplasms/*pathology
Protein-Arginine Deiminase Type 2/*metabolism
Protein-Arginine Deiminase Type 3/*metabolism
Carcinoma, Pancreatic Ductal/drug therapy ; Cell Line, Tumor ; Extracellular Vesicles/drug effects ; Humans ; Isoenzymes/antagonists & inhibitors ; Isoenzymes/metabolism ; Neoplasm Invasiveness/pathology ; Ornithine/analogs & derivatives ; Ornithine/pharmacology ; Ornithine/therapeutic use ; Pancreatic Neoplasms/drug therapy ; Prohibitins ; Protein-Arginine Deiminase Type 2/antagonists & inhibitors ; Protein-Arginine Deiminase Type 3/antagonists & inhibitors ; Protein-Arginine Deiminase Type 4/antagonists & inhibitors ; Protein-Arginine Deiminase Type 4/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Role and intervention of PAD4 in NETs in acute respiratory distress syndrome.
Autorzy:
Liu X; Department of Anesthesiology, The Affiliated Hospital of Qingdao University, No. 16, Jiangsu Road, Qingdao, Shandong, China.
Li T; Department of Oncology, The Affiliated Hospital of Qingdao University, No. 59, Haier Road, Qingdao, Shandong, China.
Chen H; Department of Anestheiology, The Qingdao Eighth People's Hospital, No. 210 Jinshui Road, Licang District, Qingdao City, Shandong, China.
Yuan L; Department of Anesthesiology, The Affiliated Hospital of Qingdao University, No. 16, Jiangsu Road, Qingdao, Shandong, China. .
Ao H; Department of Anesthesiology, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.167 North Lishi Road, Xicheng District, Beijing, China. .
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Źródło:
Respiratory research [Respir Res] 2024 Jan 30; Vol. 25 (1), pp. 63. Date of Electronic Publication: 2024 Jan 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Extracellular Traps*/metabolism
Respiratory Distress Syndrome*/diagnosis
Respiratory Distress Syndrome*/therapy
Respiratory Distress Syndrome*/metabolism
Thrombosis*
Sepsis*/metabolism
Humans ; Thromboinflammation ; Protein-Arginine Deiminase Type 4/metabolism ; Neutrophils/metabolism ; Histones/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Delayed puberty, gonadotropin abnormalities and subfertility in male Padi2/Padi4 double knockout mice.
Autorzy:
Sams KL; Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Mukai C; Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Marks BA; Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Mittal C; Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Demeter EA; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Nelissen S; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Grenier JK; Transcriptional Regulation and Expression Facility, Department of Biomedical Sciences, Cornell University, Ithaca, NY, USA.
Tate AE; Transcriptional Regulation and Expression Facility, Department of Biomedical Sciences, Cornell University, Ithaca, NY, USA.
Ahmed F; Transcriptional Regulation and Expression Facility, Department of Biomedical Sciences, Cornell University, Ithaca, NY, USA.
Coonrod SA; Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA. .; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA. .
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Źródło:
Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2022 Oct 12; Vol. 20 (1), pp. 150. Date of Electronic Publication: 2022 Oct 12.
Typ publikacji:
Journal Article
MeSH Terms:
Citrulline*
Infertility*/genetics
Protein-Arginine Deiminase Type 2/*metabolism
Protein-Arginine Deiminases/*metabolism
Animals ; Arginine ; Disease Models, Animal ; Female ; Gonadotropins ; Hydrolases/genetics ; Male ; Mice ; Mice, Knockout ; Protein-Arginine Deiminase Type 2/genetics ; Protein-Arginine Deiminases/genetics ; Testosterone
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Screening of Epigenetic Therapeutic Targets for Non-Small Cell Lung Cancer Reveals PADI4 and KDM6B as Promising Candidates.
Autorzy:
Lesbon JCC; Laboratory of Comparative and Translational Oncology, Department of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, Duque de Caxias, 225-Jardim Elite, Pirassununga 13635-900, SP, Brazil.
Garnica TK; Laboratory of Comparative and Translational Oncology, Department of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, Duque de Caxias, 225-Jardim Elite, Pirassununga 13635-900, SP, Brazil.
Xavier PLP; Laboratory of Comparative and Translational Oncology, Department of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, Duque de Caxias, 225-Jardim Elite, Pirassununga 13635-900, SP, Brazil.
Rochetti AL; Laboratory of Comparative and Translational Oncology, Department of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, Duque de Caxias, 225-Jardim Elite, Pirassununga 13635-900, SP, Brazil.
Reis RM; Molecular Oncology Research Center, Hospital de Amor, Antenor Duarte Viléla, 1331-Dr. Paulo Prata, Barretos 14784-400, SP, Brazil.; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710-057 Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4710-057 Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4805-017 Guimarães, Portugal.
Müller S; Structural Genomics Consortium, Buchmann Institute for Molecular Life Sciences, Johann Wolfgang Goethe University, Max-von-Laue-Str 15-60438, 60438 Frankfurt am Main, Germany.
Fukumasu H; Laboratory of Comparative and Translational Oncology, Department of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, Duque de Caxias, 225-Jardim Elite, Pirassununga 13635-900, SP, Brazil.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 07; Vol. 23 (19). Date of Electronic Publication: 2022 Oct 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Adenocarcinoma of Lung*/drug therapy
Adenocarcinoma of Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Jumonji Domain-Containing Histone Demethylases*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Protein-Arginine Deiminase Type 4*/genetics
Cell Line, Tumor ; Early Detection of Cancer ; Epigenesis, Genetic ; Gene Expression Regulation, Neoplastic ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Polymorphism of protein tyrosine phosphatase non-receptor type 22 and protein arginine deiminase 4 gene among Ghanaian rheumatoid arthritis patients: A case-control study.
Autorzy:
Sakyi SA; Department of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Boateng AO; Department of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Fondjo LA; Department of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Mensah KY; Department of Internal Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Opoku S; Department of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Senu E; Department of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Buckman TA; Department of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Sampson JE; Department of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
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Źródło:
International journal of rheumatic diseases [Int J Rheum Dis] 2022 Jul; Vol. 25 (7), pp. 781-786. Date of Electronic Publication: 2022 May 24.
Typ publikacji:
Journal Article
MeSH Terms:
Arthritis, Rheumatoid*/diagnosis
Arthritis, Rheumatoid*/epidemiology
Arthritis, Rheumatoid*/genetics
Protein Tyrosine Phosphatase, Non-Receptor Type 22*/genetics
Protein-Arginine Deiminase Type 4*/genetics
Case-Control Studies ; Gene Frequency ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Genotype ; Ghana/epidemiology ; Humans ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hydroquinine Inhibits the Growth of Multidrug-Resistant Pseudomonas aeruginosa via the Suppression of the Arginine Deiminase Pathway Genes.
Autorzy:
Weawsiangsang, Sattaporn (AUTHOR)
Rattanachak, Nontaporn (AUTHOR)
Jongjitvimol, Touchkanin (AUTHOR)
Jaifoo, Theerasak (AUTHOR)
Charoensit, Pensri (AUTHOR)
Viyoch, Jarupa (AUTHOR)
Ross, Sukunya (AUTHOR)
Ross, Gareth M. (AUTHOR)
Baldock, Robert A. (AUTHOR)
Jongjitwimol, Jirapas (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Sep2023, Vol. 24 Issue 18, p13914. 17p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Porphyromonas gingivalis Peptidyl Arginine Deiminase (PPAD) in the Context of the Feed-Forward Loop of Inflammation in Periodontitis.
Autorzy:
Prucsi, Zsombor (AUTHOR)
Zimny, Agnieszka (AUTHOR)
Płonczyńska, Alicja (AUTHOR)
Zubrzycka, Natalia (AUTHOR)
Potempa, Jan (AUTHOR)
Sochalska, Maja (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Aug2023, Vol. 24 Issue 16, p12922. 14p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Human Enzyme PADI4 Binds to the Nuclear Carrier Importin α3.
Autorzy:
Neira JL; Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche, Universidad Miguel Hernández, 03202 Elche, Spain.; Instituto de Biocomputación y Física de Sistemas Complejos-Unidad mixta GBsC-CSIC-BIFI, Universidad de Zaragoza, 50018 Zaragoza, Spain.
Rizzuti B; Instituto de Biocomputación y Física de Sistemas Complejos-Unidad mixta GBsC-CSIC-BIFI, Universidad de Zaragoza, 50018 Zaragoza, Spain.; CNR-NANOTEC, SS Rende (CS), Department of Physics, University of Calabria, 87036 Rende, Italy.
Abián O; Instituto de Biocomputación y Física de Sistemas Complejos-Unidad mixta GBsC-CSIC-BIFI, Universidad de Zaragoza, 50018 Zaragoza, Spain.; Instituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.; Centro de Investigación Biomédica en Red en el Área Temática de Enfermedades Hepáticas y Digestivas (CIBERehd), 28029 Madrid, Spain.; Departamento de Bioquímica y Biología Molecular y Celular, Universidad de Zaragoza, 50009 Zaragoza, Spain.
Araujo-Abad S; Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche, Universidad Miguel Hernández, 03202 Elche, Spain.; Centro de Biotecnología, Universidad Nacional de Loja, Avda. Pío Jaramillo Alvarado s/n, Loja 110111, Ecuador.
Velázquez-Campoy A; Instituto de Biocomputación y Física de Sistemas Complejos-Unidad mixta GBsC-CSIC-BIFI, Universidad de Zaragoza, 50018 Zaragoza, Spain.; Instituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.; Centro de Investigación Biomédica en Red en el Área Temática de Enfermedades Hepáticas y Digestivas (CIBERehd), 28029 Madrid, Spain.; Departamento de Bioquímica y Biología Molecular y Celular, Universidad de Zaragoza, 50009 Zaragoza, Spain.
de Juan Romero C; Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche, Universidad Miguel Hernández, 03202 Elche, Spain.; Unidad de Investigación, Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunidad Valenciana (FISABIO), Hospital General Universitario de Elche, Camí de l'Almazara 11, 03203 Elche, Spain.
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Źródło:
Cells [Cells] 2022 Jul 11; Vol. 11 (14). Date of Electronic Publication: 2022 Jul 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Karyopherins*/metabolism
Nuclear Localization Signals*/metabolism
Protein-Arginine Deiminase Type 4*/metabolism
Cell Nucleus/metabolism ; Humans ; Molecular Docking Simulation ; Protein Binding
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Molecular Factors in PAD2 ( PADI2 ) and PAD4 ( PADI4 ) Are Associated with Interstitial Lung Disease Susceptibility in Rheumatoid Arthritis Patients.
Autorzy:
Nava-Quiroz KJ; HLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Tlalpan, Mexico City 14080, Mexico.; Programa de Maestría y Doctorado en Ciencias Médicas Odontológicas y de la Salud, Universidad Nacional Autónoma de México (UNAM), Mexico City 04100, Mexico.
Rojas-Serrano J; Rheumatology Clinic, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Tlalpan, Mexico City 14080, Mexico.
Pérez-Rubio G; HLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Tlalpan, Mexico City 14080, Mexico.
Buendia-Roldan I; Translational Research Laboratory on Aging and Pulmonary Fibrosis, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Tlalpan, Mexico City 14080, Mexico.
Mejía M; Diffuse Interstitial Lung Disease Clinic, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Tlalpan, Mexico City 14080, Mexico.
Fernández-López JC; Consorcio de Genómica Computacional, Instituto Nacional de Medicina Genómica (INMEGEN), Tlalpan, Mexico City 14610, Mexico.
Rodríguez-Henríquez P; Department of Rheumatology, Hospital General Dr. Manuel Gea González, Tlalpan, Mexico City 14080, Mexico.
Ayala-Alcantar N; Banco de Sangre, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Tlalpan, Mexico City 14080, Mexico.
Ramos-Martínez E; Experimental Medicine Research Unit, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 06720, Mexico.
López-Flores LA; HLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Tlalpan, Mexico City 14080, Mexico.
Del Ángel-Pablo AD; HLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Tlalpan, Mexico City 14080, Mexico.
Falfán-Valencia R; HLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Tlalpan, Mexico City 14080, Mexico.
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Źródło:
Cells [Cells] 2023 Sep 08; Vol. 12 (18). Date of Electronic Publication: 2023 Sep 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lung Diseases, Interstitial*/genetics
Arthritis, Rheumatoid*/complications
Arthritis, Rheumatoid*/genetics
Humans ; Alleles ; Genotype ; Nucleotides ; Protein-Arginine Deiminase Type 2
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
PADI4 promotes epithelial-mesenchymal transition(EMT) in gastric cancer via the upregulation of interleukin 8.
Autorzy:
Chang XT; Department of Oncology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine, Shandong Lung Cancer Institute, Jinan, 250014, Shandong, China.; Medical Research Center of The Affiliated Hospital of Qingdao University, and Qingdao Engineering Center of Major Disease Markers, Qingdao, 266000, Shandong, China.
Wu H; Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, China.
Li HL; Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, China.
Li HL; Department of Oncology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine, Shandong Lung Cancer Institute, Jinan, 250014, Shandong, China.
Zheng YB; Department of Oncology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine, Shandong Lung Cancer Institute, Jinan, 250014, Shandong, China. .
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Źródło:
BMC gastroenterology [BMC Gastroenterol] 2022 Jan 19; Vol. 22 (1), pp. 25. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
Epithelial-Mesenchymal Transition*
Interleukin-8*/genetics
Protein-Arginine Deiminase Type 4*
Stomach Neoplasms*/genetics
Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Gene Expression Regulation, Neoplastic ; Humans ; Neoplasm Invasiveness ; Up-Regulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Expression of Non-Coding RNAs and Their Target Molecules in Rheumatoid Arthritis: A Molecular Basis for Rheumatoid Pathogenesis and Its Potential Clinical Applications.
Autorzy:
Tsai CY; Division of Allergy, Immunology & Rheumatology, Taipei Veterans General Hospital, National Yang-Ming Chiao-Tung University, Taipei 11217, Taiwan.
Hsieh SC; Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei 10002, Taiwan.
Liu CW; Division of Allergy, Immunology & Rheumatology, Taipei Veterans General Hospital, National Yang-Ming Chiao-Tung University, Taipei 11217, Taiwan.
Lu CH; Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei 10002, Taiwan.; Institute of Molecular Medicine, National Taiwan University College of Medicine, Taipei 10002, Taiwan.
Liao HT; Division of Allergy, Immunology & Rheumatology, Taipei Veterans General Hospital, National Yang-Ming Chiao-Tung University, Taipei 11217, Taiwan.
Chen MH; Division of Allergy, Immunology & Rheumatology, Taipei Veterans General Hospital, National Yang-Ming Chiao-Tung University, Taipei 11217, Taiwan.
Li KJ; Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei 10002, Taiwan.
Wu CH; Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei 10002, Taiwan.; Institute of Molecular Medicine, National Taiwan University College of Medicine, Taipei 10002, Taiwan.
Shen CY; Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei 10002, Taiwan.; Institute of Molecular Medicine, National Taiwan University College of Medicine, Taipei 10002, Taiwan.
Kuo YM; Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei 10002, Taiwan.; Institute of Molecular Medicine, National Taiwan University College of Medicine, Taipei 10002, Taiwan.
Yu CL; Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei 10002, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 May 26; Vol. 22 (11). Date of Electronic Publication: 2021 May 26.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Epigenesis, Genetic*
Gene Expression Regulation, Enzymologic*
Arthritis, Rheumatoid/*metabolism
Protein-Arginine Deiminase Type 2/*biosynthesis
Protein-Arginine Deiminase Type 4/*biosynthesis
RNA, Long Noncoding/*biosynthesis
Arthritis, Rheumatoid/genetics ; Arthritis, Rheumatoid/pathology ; Arthritis, Rheumatoid/therapy ; Humans ; Protein-Arginine Deiminase Type 2/genetics ; Protein-Arginine Deiminase Type 4/genetics ; RNA, Long Noncoding/genetics
Czasopismo naukowe
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Tytuł:
Peptidylarginine Deiminase 2 in Murine Antiviral and Autoimmune Antibody Responses.
Autorzy:
Mergaert AM; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Denny MF; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Kingstad-Bakke B; Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, WI, USA.
Bawadekar M; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Bashar SJ; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Warner TF; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Suresh M; Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, WI, USA.
Shelef MA; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.
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Źródło:
Journal of immunology research [J Immunol Res] 2022 Jan 17; Vol. 2022, pp. 5258221. Date of Electronic Publication: 2022 Jan 17 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Arthritis, Rheumatoid/*immunology
Protein-Arginine Deiminase Type 2/*metabolism
Adaptive Immunity ; Animals ; Anti-Citrullinated Protein Antibodies/metabolism ; Antibody Formation ; Antiviral Agents ; Arthritis, Experimental/immunology ; Autoantibodies/blood ; Citrullination ; Humans ; Hydrolases ; Immunity, Innate ; Mice ; Mice, Inbred DBA ; Protein-Arginine Deiminase Type 2/genetics
Czasopismo naukowe
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Tytuł:
Factors Associated with Promoted Proliferation of Osteosarcoma by Peptidylarginine Deiminase 4.
Autorzy:
Guo J; Department of Oncology, Maternal and Child Health Care Hospital of Zibo, Zibo 255029, China.
Yin L; Human Resources Department, Zibo Central Hospital, Zibo 255036, China.
Zhang X; Department of Laboratory Medicine, Zibo Central Hospital, Zibo 255036, China.
Su P; Department of Laboratory Medicine, Zibo Central Hospital, Zibo 255036, China.
Zhai Q; Center of Translational Medicine, Zibo Central Hospital, Zibo 255036, China.
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Źródło:
BioMed research international [Biomed Res Int] 2021 May 15; Vol. 2021, pp. 5596014. Date of Electronic Publication: 2021 May 15 (Print Publication: 2021).
Typ publikacji:
Journal Article
MeSH Terms:
Bone Neoplasms/*metabolism
Cell Proliferation/*drug effects
Osteosarcoma/*metabolism
Protein-Arginine Deiminase Type 4/*metabolism
Protein-Arginine Deiminase Type 4/*pharmacology
Adolescent ; Adult ; Aged ; Animals ; Bone Neoplasms/pathology ; Carcinogenesis ; Cell Line, Tumor ; Cholecystokinin ; Female ; Humans ; Male ; Mice ; Mice, Nude ; Middle Aged ; Osteosarcoma/pathology ; Peptide Fragments ; Protein-Arginine Deiminase Type 4/genetics ; Protein-Arginine Deiminases ; Signal Transduction ; Xenograft Model Antitumor Assays ; Young Adult ; beta Catenin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 1891

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