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Tytuł :
Predictive role of perioperative neutrophil to lymphocyte ratio in pediatric congenital heart disease associated with pulmonary arterial hypertension.
Autorzy :
Yin X; Department of Cardiovascular Surgery, Jinniu District, General Hospital of Western Theater Command, Rongdu Avenue No.270, Chengdu, 610083, Sichuan, China.; North Sichuan Medical College, Nanchong, Sichuan, China.
Xin M; Department of Cardiovascular Surgery, Jinniu District, General Hospital of Western Theater Command, Rongdu Avenue No.270, Chengdu, 610083, Sichuan, China.
Ding S; Department of Cardiovascular Surgery, Jinniu District, General Hospital of Western Theater Command, Rongdu Avenue No.270, Chengdu, 610083, Sichuan, China.
Gao F; Department of Cardiovascular Surgery, Jinniu District, General Hospital of Western Theater Command, Rongdu Avenue No.270, Chengdu, 610083, Sichuan, China.
Wu F; Department of Cardiovascular Surgery, Jinniu District, General Hospital of Western Theater Command, Rongdu Avenue No.270, Chengdu, 610083, Sichuan, China.
Wang J; Department of Cardiovascular Surgery, Jinniu District, General Hospital of Western Theater Command, Rongdu Avenue No.270, Chengdu, 610083, Sichuan, China.
Chen J; Department of Cardiovascular Surgery, Jinniu District, General Hospital of Western Theater Command, Rongdu Avenue No.270, Chengdu, 610083, Sichuan, China.
Jiang L; Department of Cardiovascular Surgery, Jinniu District, General Hospital of Western Theater Command, Rongdu Avenue No.270, Chengdu, 610083, Sichuan, China.
Wu X; Department of Cardiovascular Surgery, Jinniu District, General Hospital of Western Theater Command, Rongdu Avenue No.270, Chengdu, 610083, Sichuan, China.
Wang X; Department of Cardiovascular Surgery, Jinniu District, General Hospital of Western Theater Command, Rongdu Avenue No.270, Chengdu, 610083, Sichuan, China.; North Sichuan Medical College, Nanchong, Sichuan, China.
Liu J; Department of Cardiovascular Surgery, Jinniu District, General Hospital of Western Theater Command, Rongdu Avenue No.270, Chengdu, 610083, Sichuan, China.
Zhang J; Department of Cardiovascular Surgery, Jinniu District, General Hospital of Western Theater Command, Rongdu Avenue No.270, Chengdu, 610083, Sichuan, China. .; North Sichuan Medical College, Nanchong, Sichuan, China. .
He S; Department of Cardiovascular Surgery, Jinniu District, General Hospital of Western Theater Command, Rongdu Avenue No.270, Chengdu, 610083, Sichuan, China. .
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Źródło :
BMC surgery [BMC Surg] 2021 Jan 04; Vol. 21 (1), pp. 3. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Cardiac Surgical Procedures/*adverse effects
Cardiac Surgical Procedures/*methods
Heart Defects, Congenital/*surgery
Lymphocytes/*pathology
Neutrophils/*pathology
Pulmonary Arterial Hypertension/*surgery
Biomarkers/blood ; Child ; Female ; Heart Defects, Congenital/blood ; Heart Defects, Congenital/complications ; Humans ; Lymphocyte Count ; Male ; Preoperative Period ; Prognosis ; Pulmonary Arterial Hypertension/blood ; Pulmonary Arterial Hypertension/complications ; Retrospective Studies ; Stroke Volume ; Ventricular Function, Left
Czasopismo naukowe
Tytuł :
Characteristics of inflammation process in monocrotaline-induced pulmonary arterial hypertension in rats.
Autorzy :
Tang C; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, 563000, China; Department of Pharmacology, Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, 563000, China.
Luo Y; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, 563000, China; Department of Pharmacology, Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, 563000, China.
Li S; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, 563000, China; Department of Pharmacology, Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, 563000, China.
Huang B; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, 563000, China; Department of Pharmacology, Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, 563000, China.
Xu S; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, 563000, China; Department of Pharmacology, Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, 563000, China. Electronic address: .
Li L; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, 563000, China; Department of Pharmacology, Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, 563000, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Jan; Vol. 133, pp. 111081. Date of Electronic Publication: 2020 Dec 15.
Typ publikacji :
Journal Article
MeSH Terms :
Vascular Remodeling*
Cytokines/*metabolism
Inflammation/*metabolism
Inflammation Mediators/*metabolism
Pulmonary Arterial Hypertension/*metabolism
Pulmonary Artery/*metabolism
Animals ; Arterial Pressure ; Cytokines/genetics ; Disease Models, Animal ; Hypertrophy, Right Ventricular/chemically induced ; Hypertrophy, Right Ventricular/metabolism ; Hypertrophy, Right Ventricular/physiopathology ; Inflammation/chemically induced ; Inflammation/pathology ; Inflammation/physiopathology ; Macrophages/metabolism ; Macrophages/pathology ; Male ; Monocrotaline ; Phosphatidylinositol 3-Kinase/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Pulmonary Arterial Hypertension/chemically induced ; Pulmonary Arterial Hypertension/pathology ; Pulmonary Arterial Hypertension/physiopathology ; Pulmonary Artery/pathology ; Pulmonary Artery/physiopathology ; Rats, Sprague-Dawley ; Signal Transduction ; Time Factors
Czasopismo naukowe
Tytuł :
Stem/Progenitor Cells and Pulmonary Arterial Hypertension.
Autorzy :
Pu X; Department of Cardiology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China (X.P., L.D., Y.H., Q.X.).
Du L; Department of Cardiology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China (X.P., L.D., Y.H., Q.X.).
Hu Y; Department of Cardiology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China (X.P., L.D., Y.H., Q.X.).
Fan Y; Department of Respiratory Disease, Xinqiao Hospital, Third Military Medical University, Chongqing, China (Y.F.).
Xu Q; Department of Cardiology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China (X.P., L.D., Y.H., Q.X.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Jan; Vol. 41 (1), pp. 167-178. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Mesenchymal Stem Cell Transplantation*
Vascular Remodeling*
Endothelial Progenitor Cells/*transplantation
Endothelium, Vascular/*pathology
Induced Pluripotent Stem Cells/*transplantation
Pulmonary Arterial Hypertension/*surgery
Pulmonary Artery/*pathology
Animals ; Arterial Pressure ; Endothelial Progenitor Cells/metabolism ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/physiopathology ; Humans ; Induced Pluripotent Stem Cells/metabolism ; Phenotype ; Pulmonary Arterial Hypertension/metabolism ; Pulmonary Arterial Hypertension/pathology ; Pulmonary Arterial Hypertension/physiopathology ; Pulmonary Artery/metabolism ; Pulmonary Artery/physiopathology
Czasopismo naukowe
Tytuł :
Sera and lungs metabonomics reveals key metabolites of resveratrol protecting against PAH in rats.
Autorzy :
Sun X; Department of Pharmacy, Fourth Affiliated Hospital, Harbin Medical University, Harbin, 150001, China.
Zhao B; College of Basic Medical Sciences, Harbin Medical University, Daqing, 163319, China.
Qu H; College of Pharmacy, Harbin Medical University, Daqing, 163319, China.
Chen S; College of Pharmacy, Harbin Medical University, Daqing, 163319, China.
Hao X; Inspection Institute, Harbin Medical University, Daqing, Heilongjiang Province, 163319, China.
Chen S; College of Pharmacy, Harbin Medical University, Daqing, 163319, China.
Qin Z; College of Pharmacy, Harbin Medical University, Daqing, 163319, China.
Chen G; College of Pharmacy, Harbin Medical University, Daqing, 163319, China. Electronic address: .
Fan Y; College of Basic Medical Sciences, Harbin Medical University, Daqing, 163319, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Jan; Vol. 133, pp. 110910. Date of Electronic Publication: 2020 Dec 15.
Typ publikacji :
Journal Article
MeSH Terms :
Metabolomics*
Energy Metabolism/*drug effects
Lung/*drug effects
Pulmonary Arterial Hypertension/*drug therapy
Resveratrol/*pharmacology
Animals ; Biomarkers/blood ; Chromatography, High Pressure Liquid ; Disease Models, Animal ; Hypoxia/complications ; Lung/metabolism ; Male ; Pulmonary Arterial Hypertension/blood ; Pulmonary Arterial Hypertension/etiology ; Rats, Wistar ; Spectrometry, Mass, Electrospray Ionization
Czasopismo naukowe
Tytuł :
Long-term Outcomes and Survival in Moderate-severe Portopulmonary Hypertension After Liver Transplant.
Autorzy :
Sadd CJ; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI.
Osman F; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI.
Li Z; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI.
Chybowski A; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI.
Decker C; School of Pharmacy, University of Wisconsin-Madison, Madison, WI.
Henderson B; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI.
Goss KN; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI.
Hammel LL; Department of Anesthesiology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI.
Runo JR; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI.
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Źródło :
Transplantation [Transplantation] 2021 Feb 01; Vol. 105 (2), pp. 346-353.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Liver Transplantation*/adverse effects
Liver Transplantation*/mortality
Antihypertensive Agents/*administration & dosage
Arterial Pressure/*drug effects
End Stage Liver Disease/*surgery
Hypertension, Portal/*drug therapy
Portal Pressure/*drug effects
Pulmonary Arterial Hypertension/*drug therapy
Pulmonary Artery/*drug effects
Vasodilator Agents/*administration & dosage
Administration, Oral ; End Stage Liver Disease/diagnosis ; End Stage Liver Disease/mortality ; End Stage Liver Disease/physiopathology ; Female ; Humans ; Hypertension, Portal/diagnosis ; Hypertension, Portal/mortality ; Hypertension, Portal/physiopathology ; Male ; Middle Aged ; Pulmonary Arterial Hypertension/diagnosis ; Pulmonary Arterial Hypertension/mortality ; Pulmonary Arterial Hypertension/physiopathology ; Pulmonary Artery/physiopathology ; Retrospective Studies ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Hemodynamic Response to Treatment and Outcomes in Pulmonary Hypertension Associated With Interstitial Lung Disease Versus Pulmonary Arterial Hypertension in Systemic Sclerosis: Data From a Study Identifying Prognostic Factors in Pulmonary Hypertension Associated With Interstitial Lung Disease.
Autorzy :
Chauvelot L; Hospices Civils de Lyon, Centre de Référence National des Maladies Pulmonaires Rares, Centre de Compétence de l'Hypertension Pulmonaire, Hôpital Louis Pradel, UMR 754, Université Claude Bernard Lyon 1, OrphaLung, RespiFil, and ERN-LUNG, Lyon, France.
Gamondes D; Hospices Civils de Lyon and Hôpital Louis Pradel, Lyon, France.
Berthiller J; Hospices Civils de Lyon, Université Claude Bernard Lyon 1, and Health Services and Performance Research (HESPER) EA7425, Lyon, France.
Nieves A; Centre de Compétences des Maladies Pulmonaires Rares, and Hôpital Nord, AP-HM, Marseille, France.
Renard S; Hôpital de la Timone, AP-HM, Marseille, France.
Catella-Chatron J; INSERM U1059 and CHU de Saint-Etienne, Saint-Etienne, France.
Ahmad K; Hospices Civils de Lyon, Centre de Référence National des Maladies Pulmonaires Rares, Centre de Compétence de l'Hypertension Pulmonaire, Hôpital Louis Pradel, UMR 754, Université Claude Bernard Lyon 1, OrphaLung, RespiFil, and ERN-LUNG, Lyon, France.
Bertoletti L; INSERM U1059 and CHU de Saint-Etienne, Saint-Etienne, France.
Camara B; Clinique Universitaire de Pneumologie and CHU de Grenoble Alpes, Grenoble, France.
Gomez E; CHRU de Nancy, Vandœuvre-lès-Nancy, France.
Launay D; Université de Lille, CHU de Lille, and Centre de Référence des Maladies Systémiques et Auto-Immunes Rares, Lille, France.
Montani D; Hôpital Bicêtre, AP-HP, Centre de Référence de l'Hypertension Pulmonaire, INSERM U999, Université Paris-Saclay, Paris, France.
Mornex JF; Hospices Civils de Lyon, Centre de Référence National des Maladies Pulmonaires Rares, Centre de Compétence de l'Hypertension Pulmonaire, Hôpital Louis Pradel, UMR 754, Université Claude Bernard Lyon 1, OrphaLung, RespiFil, and ERN-LUNG, Lyon, France.
Prévot G; Centre de Compétences des Maladies Pulmonaires Rares, CHU de Toulouse, and Hôpital Larrey, Toulouse, France.
Sanchez O; Hôpital Européen Georges Pompidou, AP-HP, Centre de Compétences des Maladies Pulmonaires Rares, Université Paris Descartes, INSERM U1140, Paris, France.
Schott AM; Centre de Compétences des Maladies Pulmonaires Rares, and Hôpital Nord, AP-HM, Marseille, France.
Subtil F; Université de Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5558, Villeurbanne, France, and Hospices Civils de Lyon, Lyon, France.
Traclet J; Hospices Civils de Lyon, Centre de Référence National des Maladies Pulmonaires Rares, Centre de Compétence de l'Hypertension Pulmonaire, Hôpital Louis Pradel, UMR 754, Université Claude Bernard Lyon 1, OrphaLung, RespiFil, and ERN-LUNG, Lyon, France.
Turquier S; Hospices Civils de Lyon, Centre de Référence National des Maladies Pulmonaires Rares, Centre de Compétence de l'Hypertension Pulmonaire, Hôpital Louis Pradel, UMR 754, Université Claude Bernard Lyon 1, OrphaLung, RespiFil, and ERN-LUNG, Lyon, France.
Zeghmar S; Hospices Civils de Lyon, Centre de Référence National des Maladies Pulmonaires Rares, Centre de Compétence de l'Hypertension Pulmonaire, Hôpital Louis Pradel, UMR 754, Université Claude Bernard Lyon 1, OrphaLung, RespiFil, and ERN-LUNG, Lyon, France.
Habib G; Hôpital de la Timone, AP-HM, Marseille, France.
Reynaud-Gaubert M; Centre de Compétences des Maladies Pulmonaires Rares, and Hôpital Nord, AP-HM, Marseille, France.
Humbert M; Hôpital Bicêtre, AP-HP, Centre de Référence de l'Hypertension Pulmonaire, INSERM U999, Université Paris-Saclay, Paris, France.
Cottin V; Hospices Civils de Lyon, Centre de Référence National des Maladies Pulmonaires Rares, Centre de Compétence de l'Hypertension Pulmonaire, Hôpital Louis Pradel, UMR 754, Université Claude Bernard Lyon 1, OrphaLung, RespiFil, and ERN-LUNG, Lyon, France.
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Źródło :
Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2021 Feb; Vol. 73 (2), pp. 295-304. Date of Electronic Publication: 2020 Dec 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hemodynamics*
Endothelin Receptor Antagonists/*therapeutic use
Immunosuppressive Agents/*therapeutic use
Lung Diseases, Interstitial/*drug therapy
Phosphodiesterase 5 Inhibitors/*therapeutic use
Pulmonary Arterial Hypertension/*drug therapy
Scleroderma, Systemic/*drug therapy
Aged ; Cardiac Catheterization ; Epoprostenol/analogs & derivatives ; Female ; Forced Expiratory Volume ; Humans ; Hypertension, Pulmonary/complications ; Hypertension, Pulmonary/drug therapy ; Hypertension, Pulmonary/physiopathology ; Lung Diseases, Interstitial/complications ; Lung Diseases, Interstitial/physiopathology ; Male ; Middle Aged ; Oxygen Inhalation Therapy/statistics & numerical data ; Prognosis ; Pulmonary Arterial Hypertension/complications ; Pulmonary Arterial Hypertension/physiopathology ; Pulmonary Diffusing Capacity ; Scleroderma, Systemic/complications ; Scleroderma, Systemic/physiopathology ; Survival Rate ; Treatment Outcome ; Vital Capacity ; Walk Test
Czasopismo naukowe
Tytuł :
Protective effects of dioscin on vascular remodeling in pulmonary arterial hypertension via adjusting GRB2/ERK/PI3K-AKT signal.
Autorzy :
Yang Y; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China.
Yin L; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China.
Zhu M; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China.
Song S; College of Pharmacy, Shenzhen Technology University, Shenzhen 518118, China.
Sun C; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China.
Han X; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China.
Xu Y; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China.
Zhao Y; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China.
Qi Y; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China.
Xu L; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China; Key Laboratory of Ethnomedicine (Minzu University of China), Ministry of Education, Beijing 100081, China. Electronic address: .
Peng JY; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China; Key Laboratory for Basic and Applied Research on Pharmacodynamic Substances of Traditional Chinese Medicine of Liaoning Province, Dalian Medical University, Dalian 116044, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Jan; Vol. 133, pp. 111056. Date of Electronic Publication: 2020 Nov 28.
Typ publikacji :
Journal Article
MeSH Terms :
Diosgenin/*analogs & derivatives
Extracellular Signal-Regulated MAP Kinases/*metabolism
GRB2 Adaptor Protein/*metabolism
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Phosphatidylinositol 3-Kinase/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Pulmonary Arterial Hypertension/*drug therapy
Vascular Remodeling/*drug effects
Animals ; Apoptosis/drug effects ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Diosgenin/pharmacology ; Disease Models, Animal ; GRB2 Adaptor Protein/genetics ; Male ; Muscle, Smooth, Vascular/enzymology ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/enzymology ; Myocytes, Smooth Muscle/pathology ; Phosphorylation ; Pulmonary Arterial Hypertension/enzymology ; Pulmonary Arterial Hypertension/pathology ; Pulmonary Artery/drug effects ; Pulmonary Artery/enzymology ; Pulmonary Artery/pathology ; Rats, Sprague-Dawley ; Signal Transduction
Czasopismo naukowe
Tytuł :
The prevalence and incidence rate of pulmonary arterial hypertension in systemic sclerosis: Systematic review and meta-analysis.
Autorzy :
Rubio-Rivas M; Autoimmune Diseases Unit, Department of Internal Medicine, Bellvitge University Hospital, Bellvitge Biomedical Research Institute-IDIBELL, University of Barcelona, Barcelona, Spain. Electronic address: .
Homs NA; Autoimmune Diseases Unit, Department of Internal Medicine, Bellvitge University Hospital, Bellvitge Biomedical Research Institute-IDIBELL, University of Barcelona, Barcelona, Spain.
Cuartero D; Autoimmune Diseases Unit, Department of Internal Medicine, Bellvitge University Hospital, Bellvitge Biomedical Research Institute-IDIBELL, University of Barcelona, Barcelona, Spain.
Corbella X; Autoimmune Diseases Unit, Department of Internal Medicine, Bellvitge University Hospital, Bellvitge Biomedical Research Institute-IDIBELL, University of Barcelona, Barcelona, Spain; Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Barcelona, Spain; Group of Evaluation of Health Determinants and Health Policies, Hestia Chair in Integrated Health and Social Care, Barcelona, Spain.
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Źródło :
Autoimmunity reviews [Autoimmun Rev] 2021 Jan; Vol. 20 (1), pp. 102713. Date of Electronic Publication: 2020 Nov 13.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Pulmonary Arterial Hypertension*/complications
Pulmonary Arterial Hypertension*/epidemiology
Scleroderma, Systemic*/complications
Scleroderma, Systemic*/epidemiology
Humans ; Incidence ; Prevalence
Czasopismo naukowe
Tytuł :
Altered Macrophage Polarization Induces Experimental Pulmonary Hypertension and Is Observed in Patients With Pulmonary Arterial Hypertension.
Autorzy :
Zawia A; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Arnold ND; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
West L; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Pickworth JA; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Turton H; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Iremonger J; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Braithwaite AT; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Cañedo J; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Johnston SA; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Thompson AAR; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Miller G; Department of Oncology and Metabolism (G.M.), University of Sheffield, United Kingdom.; College of Medical and Dental Science, University of Birmingham, United Kingdom (G.M.).
Lawrie A; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Jan; Vol. 41 (1), pp. 430-445. Date of Electronic Publication: 2020 Nov 05.
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Macrophage Activation*
Vascular Remodeling*
Macrophages, Alveolar/*pathology
Muscle, Smooth, Vascular/*pathology
Pulmonary Arterial Hypertension/*pathology
Adult ; Aged ; Animals ; Antigens, CD/genetics ; Antigens, Differentiation, Myelomonocytic/genetics ; Case-Control Studies ; Cell Proliferation ; Diphtheria Toxin/genetics ; Disease Models, Animal ; Female ; Humans ; Hypoxia/complications ; Macrophages, Alveolar/metabolism ; Male ; Mice, Transgenic ; Middle Aged ; Muscle, Smooth, Vascular/metabolism ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology ; Paracrine Communication ; Peptide Fragments/genetics ; Phenotype ; Pulmonary Arterial Hypertension/etiology ; Pulmonary Arterial Hypertension/metabolism ; Pulmonary Artery/metabolism ; Pulmonary Artery/pathology ; Sex Factors
Czasopismo naukowe
Tytuł :
A meta-analysis of comorbidities in COVID-19: Which diseases increase the susceptibility of SARS-CoV-2 infection?
Autorzy :
Singh MK; CSIR-Institute of Genomics and Integrative Biology, New Delhi, 110007, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Mobeen A; CSIR-Institute of Genomics and Integrative Biology, New Delhi, 110007, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Chandra A; CSIR-Institute of Genomics and Integrative Biology, New Delhi, 110007, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Joshi S; Jamia Hamdard, Hamdard Nagar, New Delhi, 110062, India.
Ramachandran S; CSIR-Institute of Genomics and Integrative Biology, New Delhi, 110007, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Electronic address: .
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Źródło :
Computers in biology and medicine [Comput Biol Med] 2021 Mar; Vol. 130, pp. 104219. Date of Electronic Publication: 2021 Jan 16.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Angiotensin-Converting Enzyme 2/*biosynthesis
COVID-19/*metabolism
Diabetes Mellitus, Type 2/*metabolism
Neoplasm Proteins/*metabolism
Neoplasms/*metabolism
Non-alcoholic Fatty Liver Disease/*metabolism
Psoriasis/*metabolism
Pulmonary Arterial Hypertension/*metabolism
SARS-CoV-2/*metabolism
COVID-19/mortality ; Comorbidity ; Diabetes Mellitus, Type 2/mortality ; Gene Expression Regulation, Neoplastic ; Gene Expression Regulation, Viral ; Humans ; Neoplasms/mortality ; Non-alcoholic Fatty Liver Disease/mortality ; Psoriasis/mortality ; Pulmonary Arterial Hypertension/mortality ; Signal Transduction
Czasopismo naukowe
Tytuł :
Reply to Weatherald et al. : Pulmonary Vascular Resistance in Pulmonary Arterial Hypertension: La Pièce de Résistance?
Autorzy :
Badagliacca R; Sapienza University of Rome Rome, Italy.
D'Alto M; University of Campania Luigi Vanvitelli Naples, Italy.
Ghio S; Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S Matteo Pavia, Italy and.
Vizza CD; Sapienza University of Rome Rome, Italy.
Naeije R; Free University of Brussels Brussels, Belgium.
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Źródło :
American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2021 Feb 15; Vol. 203 (4), pp. 525-526.
Typ publikacji :
Letter; Comment
MeSH Terms :
Pulmonary Arterial Hypertension*
Familial Primary Pulmonary Hypertension ; Hemodynamics ; Humans ; Risk Reduction Behavior ; Vascular Resistance
Opinia redakcyjna
Tytuł :
When "AMBITION" Isn't Good Enough: Risk Status and Dual Oral Therapy in Pulmonary Arterial Hypertension.
Autorzy :
Schoenberg NC; Pulmonary and Critical Care Division Beth Israel Deaconess Medical Center Boston, Massachusetts and.
Farber HW; Division of Pulmonary, Critical Care and Sleep Medicine Tufts Medical Center Boston, Massachusetts.
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Źródło :
American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2021 Feb 15; Vol. 203 (4), pp. 410-411.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Pulmonary Arterial Hypertension*
Antihypertensive Agents/therapeutic use ; Hemodynamics ; Humans ; Risk Reduction Behavior ; Tadalafil
Opinia redakcyjna
Tytuł :
Pulmonary Vascular Resistance in Pulmonary Arterial Hypertension: La Pièce de Résistance?
Autorzy :
Weatherald J; University of CalgaryCalgary Alberta, Canada.; Libin Cardiovascular Institute Calgary, Alberta, Canada.
Boucly A; Hôpital Marie Lannelongue Le Plessis-Robinson, France.; Université Paris-Saclay Le Kremlin-Bicêtre, France and.; Hôpital Bicêtre Le Kremlin-Bicêtre, France.
Savale L; Hôpital Marie Lannelongue Le Plessis-Robinson, France.; Université Paris-Saclay Le Kremlin-Bicêtre, France and.; Hôpital Bicêtre Le Kremlin-Bicêtre, France.
Jaïs X; Hôpital Marie Lannelongue Le Plessis-Robinson, France.; Université Paris-Saclay Le Kremlin-Bicêtre, France and.; Hôpital Bicêtre Le Kremlin-Bicêtre, France.
Montani D; Hôpital Marie Lannelongue Le Plessis-Robinson, France.; Université Paris-Saclay Le Kremlin-Bicêtre, France and.; Hôpital Bicêtre Le Kremlin-Bicêtre, France.
Humbert M; Hôpital Marie Lannelongue Le Plessis-Robinson, France.; Université Paris-Saclay Le Kremlin-Bicêtre, France and.; Hôpital Bicêtre Le Kremlin-Bicêtre, France.
Sitbon O; Hôpital Marie Lannelongue Le Plessis-Robinson, France.; Université Paris-Saclay Le Kremlin-Bicêtre, France and.; Hôpital Bicêtre Le Kremlin-Bicêtre, France.
Pokaż więcej
Źródło :
American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2021 Feb 15; Vol. 203 (4), pp. 524-525.
Typ publikacji :
Letter; Comment
MeSH Terms :
Pulmonary Arterial Hypertension*
Familial Primary Pulmonary Hypertension ; Hemodynamics ; Humans ; Risk Reduction Behavior ; Vascular Resistance
Opinia redakcyjna
Tytuł :
Sex Hormones across the Menstrual Cycle in Pulmonary Arterial Hypertension: Adding a New Layer of Complexity.
Autorzy :
Austin ED; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee.
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Źródło :
Annals of the American Thoracic Society [Ann Am Thorac Soc] 2021 Feb; Vol. 18 (2), pp. 209-211.
Typ publikacji :
Editorial; Research Support, N.I.H., Extramural; Comment
MeSH Terms :
Pulmonary Arterial Hypertension*
Female ; Gonadal Steroid Hormones ; Humans ; Menstrual Cycle
Raport
Tytuł :
Keratin 1: A negative regulator of inflammation and potential treatment for pulmonary arterial hypertension.
Autorzy :
Trittmann JK; Center for Perinatal Research, Abigail Wexner Research Institute at Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, OH, USA.
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Źródło :
Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2021 Feb; Vol. 231 (2), pp. e13594. Date of Electronic Publication: 2020 Dec 22.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Hypertension*
Pulmonary Arterial Hypertension*
Humans ; Inflammation ; Keratin-1 ; Muscle, Smooth ; Pulmonary Artery
Opinia redakcyjna
Tytuł :
Reply to Non and Chang: Challenging the Role of Genetic Ancestry in Explaining Racial/Ethnic Health Disparities.
Autorzy :
Karnes JH; University of Arizona Tucson, Arizona.
Schwantes-An TH; Indiana University Indianapolis, Indiana and.
Kittles R; City of Hope Comprehensive Cancer Center Duarte, California.
Desai AA; Indiana University Indianapolis, Indiana and.
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Źródło :
American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2021 Feb 01; Vol. 203 (3), pp. 398-399.
Typ publikacji :
Letter; Comment
MeSH Terms :
Pulmonary Arterial Hypertension*
Ethnic Groups/genetics ; European Continental Ancestry Group/genetics ; Humans
Opinia redakcyjna
Tytuł :
Challenging the Role of Genetic Ancestry in Explaining Racial/Ethnic Health Disparities.
Autorzy :
Non AL; University of California, San Diego La Jolla, California.
Chang SY; University of California, San Diego La Jolla, California.
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Źródło :
American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2021 Feb 01; Vol. 203 (3), pp. 397-398.
Typ publikacji :
Letter; Comment
MeSH Terms :
Pulmonary Arterial Hypertension*
Ethnic Groups/genetics ; European Continental Ancestry Group/genetics ; Humans
Opinia redakcyjna
Tytuł :
Breathing for Two.
Autorzy :
Rudder M; From Women and Infants' Hospital (M. Rudder, M. Russo) and Rhode Island Hospital (C.E.V.), Warren Alpert Medical School of Brown University, Providence.
Russo M; From Women and Infants' Hospital (M. Rudder, M. Russo) and Rhode Island Hospital (C.E.V.), Warren Alpert Medical School of Brown University, Providence.
Ventetuolo CE; From Women and Infants' Hospital (M. Rudder, M. Russo) and Rhode Island Hospital (C.E.V.), Warren Alpert Medical School of Brown University, Providence.
Pokaż więcej
Źródło :
The New England journal of medicine [N Engl J Med] 2021 Jan 07; Vol. 384 (1), pp. 61-68.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Dyspnea/*etiology
Pregnancy Complications, Cardiovascular/*diagnosis
Pulmonary Arterial Hypertension/*diagnosis
Adult ; Cardiac Catheterization ; Diagnosis, Differential ; Echocardiography ; Electrocardiography ; Erythema Infectiosum/complications ; Erythema Infectiosum/diagnosis ; Female ; Heart Failure/diagnosis ; Heart Ventricles/diagnostic imaging ; Humans ; Parvovirus B19, Human/isolation & purification ; Pregnancy ; Pregnancy Complications, Infectious/diagnosis ; Pulmonary Arterial Hypertension/complications ; Radiography, Thoracic ; Respiration ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł :
Recent advances in the approach to hepatopulmonary syndrome and portopulmonary hypertension.
Autorzy :
Raevens S; Hepatology Research Unit, Ghent University, Ghent, Belgium.
Geerts A; Hepatology Research Unit, Ghent University, Ghent, Belgium.
Devisscher L; Hepatology Research Unit, Ghent University, Ghent, Belgium.; Department of Basic and Applied Medical Sciences, Gut-Liver Immunopharmacology Unit, Ghent University, Ghent, Belgium.
Van Vlierberghe H; Hepatology Research Unit, Ghent University, Ghent, Belgium.
Van Steenkiste C; Hepatology Research Unit, Ghent University, Ghent, Belgium.
Colle I; Hepatology Research Unit, Ghent University, Ghent, Belgium.
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Źródło :
Acta gastro-enterologica Belgica [Acta Gastroenterol Belg] 2021 Jan-Mar; Vol. 84 (1), pp. 95-99.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Hepatopulmonary Syndrome*/diagnosis
Hepatopulmonary Syndrome*/therapy
Hypertension, Portal*/complications
Hypertension, Portal*/diagnosis
Hypertension, Portal*/therapy
Hypertension, Pulmonary*/diagnosis
Hypertension, Pulmonary*/etiology
Hypertension, Pulmonary*/therapy
Pulmonary Arterial Hypertension*
Humans ; Liver Cirrhosis
Czasopismo naukowe
Tytuł :
Shuttling toward Improved Clinic-based Assessment of Exercise Capacity in Pulmonary Arterial Hypertension.
Autorzy :
Brittain EL; Division of Cardiovascular Medicine and Vanderbilt Translational and Clinical Research Center, Vanderbilt University Medical Center, Nashville, Tennessee.
Pokaż więcej
Źródło :
Annals of the American Thoracic Society [Ann Am Thorac Soc] 2021 Jan; Vol. 18 (1), pp. 26-27.
Typ publikacji :
Editorial; Research Support, N.I.H., Extramural; Comment
MeSH Terms :
Exercise Test*
Pulmonary Arterial Hypertension*
Exercise Tolerance ; Familial Primary Pulmonary Hypertension ; Humans ; Walking
Raport

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