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Wyszukujesz frazę ""autoantigens"" wg kryterium: Temat


Tytuł :
Conformational maps of human 20S proteasomes reveal PA28- and immuno-dependent inter-ring crosstalks.
Autorzy :
Lesne J; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France.; Centre de Biologie Structurale, CNRS, Université de Montpellier, INSERM, 34090, Montpellier, France.
Locard-Paulet M; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France.; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.
Parra J; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France.
Zivković D; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France.
Menneteau T; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France.; Institute of Structural and Molecular Biology, Division of Biosciences, University College London, London, WC1E 6BT, UK.
Bousquet MP; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France.
Burlet-Schiltz O; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France.
Marcoux J; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France. .
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Źródło :
Nature communications [Nat Commun] 2020 Dec 01; Vol. 11 (1), pp. 6140. Date of Electronic Publication: 2020 Dec 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autoantigens/*metabolism
Muscle Proteins/*metabolism
Proteasome Endopeptidase Complex/*chemistry
Allosteric Regulation ; Autoantigens/chemistry ; Autoantigens/genetics ; Humans ; Mass Spectrometry ; Muscle Proteins/chemistry ; Muscle Proteins/genetics ; Proteasome Endopeptidase Complex/genetics ; Proteasome Endopeptidase Complex/metabolism ; Protein Binding
Czasopismo naukowe
Tytuł :
The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction.
Autorzy :
Smith EM; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.
Benbahouche NEH; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.
Morris K; MRC Toxicology Unit, University of Cambridge, Leicester LE1 9HN, UK.
Wilczynska A; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1QH, UK.
Gillen S; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.
Schmidt T; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.
Meijer HA; Division of Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Jukes-Jones R; MRC Toxicology Unit, University of Cambridge, Leicester LE1 9HN, UK.
Cain K; MRC Toxicology Unit, University of Cambridge, Leicester LE1 9HN, UK.
Jones C; MRC Toxicology Unit, University of Cambridge, Leicester LE1 9HN, UK.
Stoneley M; MRC Toxicology Unit, University of Cambridge, Leicester LE1 9HN, UK.
Waldron JA; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.
Bell C; Cancer Research UK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK.
Fonseca BD; PrimerGen Ltd, Viseu, Portugal.
Blagden S; Department of Oncology, University of Oxford, Oxford, OX3 7LE, UK.
Willis AE; MRC Toxicology Unit, University of Cambridge, Leicester LE1 9HN, UK.
Bushell M; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1QH, UK.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Jan 11; Vol. 49 (1), pp. 458-478.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autoantigens/*physiology
Poly(A)-Binding Protein I/*physiology
Polyribosomes/*metabolism
Protein Biosynthesis/*physiology
RNA, Messenger/*metabolism
Ribonucleoproteins/*physiology
TOR Serine-Threonine Kinases/*physiology
5' Untranslated Regions/genetics ; Autoantigens/genetics ; Gene Expression Regulation ; Genes, Reporter ; HeLa Cells ; Humans ; Mechanistic Target of Rapamycin Complex 1/antagonists & inhibitors ; Mechanistic Target of Rapamycin Complex 2/antagonists & inhibitors ; Mutagenesis, Site-Directed ; Mutation, Missense ; Naphthyridines/pharmacology ; Point Mutation ; Protein Biosynthesis/genetics ; RNA Interference ; RNA, Messenger/genetics ; RNA-Binding Proteins/isolation & purification ; RNA-Binding Proteins/metabolism ; Recombinant Fusion Proteins/metabolism ; Ribonucleoproteins/genetics
Czasopismo naukowe
Tytuł :
Early combination treatment of immune thrombocytopenia: Is this the way?
Autorzy :
Bussel JB; Division of Hematology/Oncology, Weill Cornell Medicine, New York, New York, USA.
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Źródło :
American journal of hematology [Am J Hematol] 2020 Dec; Vol. 95 (12), pp. 1452-1453.
Typ publikacji :
Journal Article
MeSH Terms :
Autoantigens/*administration & dosage
Iodide Peroxidase/*administration & dosage
Iron-Binding Proteins/*administration & dosage
Pregnancy Complications, Hematologic/*drug therapy
Purpura, Thrombocytopenic, Idiopathic/*drug therapy
Rituximab/*administration & dosage
Adult ; Autoantigens/adverse effects ; Dexamethasone/administration & dosage ; Dexamethasone/adverse effects ; Drug Therapy, Combination ; Female ; Humans ; Iodide Peroxidase/adverse effects ; Iron-Binding Proteins/adverse effects ; Male ; Pregnancy ; Rituximab/adverse effects
Czasopismo naukowe
Tytuł :
LAMP3 induces apoptosis and autoantigen release in Sjögren's syndrome patients.
Autorzy :
Tanaka T; National Institute of Dental and Craniofacial Research, National Institutes of Health, NIH 10 Center Dr., Bethesda, MD, 20892, USA.
Warner BM; National Institute of Dental and Craniofacial Research, National Institutes of Health, NIH 10 Center Dr., Bethesda, MD, 20892, USA.
Odani T; National Institute of Dental and Craniofacial Research, National Institutes of Health, NIH 10 Center Dr., Bethesda, MD, 20892, USA.
Ji Y; National Institute of Dental and Craniofacial Research, National Institutes of Health, NIH 10 Center Dr., Bethesda, MD, 20892, USA.
Mo YQ; National Institute of Dental and Craniofacial Research, National Institutes of Health, NIH 10 Center Dr., Bethesda, MD, 20892, USA.
Nakamura H; National Institute of Dental and Craniofacial Research, National Institutes of Health, NIH 10 Center Dr., Bethesda, MD, 20892, USA.
Jang SI; National Institute of Dental and Craniofacial Research, National Institutes of Health, NIH 10 Center Dr., Bethesda, MD, 20892, USA.
Yin H; National Institute of Dental and Craniofacial Research, National Institutes of Health, NIH 10 Center Dr., Bethesda, MD, 20892, USA.
Michael DG; National Institute of Dental and Craniofacial Research, National Institutes of Health, NIH 10 Center Dr., Bethesda, MD, 20892, USA.
Hirata N; Division of Cancer Biology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan.
Suizu F; Division of Cancer Biology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan.
Ishigaki S; Division of Cancer Biology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan.
Oliveira FR; Department of Clinical Medicine, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil.
Motta ACF; Department of Stomatology, Public Health and Forensic Dentistry, School of Dentistry of Ribeirão Preto, University of Sao Paulo, Ribeirao Preto, Brazil.
Ribeiro-Silva A; Department of Pathology and Legal Medicine, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, SP, Brazil.
Rocha EM; Department of Ophthalmology, Otorhinolaryngology, Head and Neck Surgery, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil.
Atsumi T; Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Noguchi M; Division of Cancer Biology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan.
Chiorini JA; National Institute of Dental and Craniofacial Research, National Institutes of Health, NIH 10 Center Dr., Bethesda, MD, 20892, USA. .
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Źródło :
Scientific reports [Sci Rep] 2020 Sep 16; Vol. 10 (1), pp. 15169. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Autoantigens/*metabolism
Lysosome-Associated Membrane Glycoproteins/*immunology
Neoplasm Proteins/*immunology
Sjogren's Syndrome/*immunology
Sjogren's Syndrome/*pathology
Apoptosis/immunology ; Autoantibodies/blood ; Autoantigens/genetics ; Autoantigens/immunology ; Case-Control Studies ; Caspase 3/genetics ; Caspase 3/metabolism ; Cell Line ; Extracellular Vesicles/immunology ; Gene Expression Profiling ; Humans ; Lysosome-Associated Membrane Glycoproteins/genetics ; Neoplasm Proteins/genetics ; Ribonucleoproteins/genetics ; Ribonucleoproteins/immunology ; Salivary Glands, Minor/immunology ; Salivary Glands, Minor/pathology ; Sjogren's Syndrome/genetics ; Up-Regulation
Czasopismo naukowe
Tytuł :
Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.
Autorzy :
Burnett DL; Garvan Institute of Medical Research, University of New South Wales (UNSW) Sydney, Darlinghurst, NSW 2010, Australia.; St Vincent's Clinical School, Department of Medicine, UNSW Sydney, NSW 2052, Australia.
Schofield P; Garvan Institute of Medical Research, University of New South Wales (UNSW) Sydney, Darlinghurst, NSW 2010, Australia.; St Vincent's Clinical School, Department of Medicine, UNSW Sydney, NSW 2052, Australia.
Langley DB; Garvan Institute of Medical Research, University of New South Wales (UNSW) Sydney, Darlinghurst, NSW 2010, Australia.
Jackson J; Garvan Institute of Medical Research, University of New South Wales (UNSW) Sydney, Darlinghurst, NSW 2010, Australia.
Bourne K; Garvan Institute of Medical Research, University of New South Wales (UNSW) Sydney, Darlinghurst, NSW 2010, Australia.
Wilson E; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3168, Australia.
Porebski BT; Medical Research Council Laboratory of Molecular Biology, CB2 OQH Cambridge, United Kingdom.
Buckle AM; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3168, Australia.
Brink R; Garvan Institute of Medical Research, University of New South Wales (UNSW) Sydney, Darlinghurst, NSW 2010, Australia.; St Vincent's Clinical School, Department of Medicine, UNSW Sydney, NSW 2052, Australia.
Goodnow CC; Garvan Institute of Medical Research, University of New South Wales (UNSW) Sydney, Darlinghurst, NSW 2010, Australia; .; St Vincent's Clinical School, Department of Medicine, UNSW Sydney, NSW 2052, Australia.; UNSW Cellular Genomics Futures Institute, UNSW Sydney, NSW 2052, Australia.
Christ D; Garvan Institute of Medical Research, University of New South Wales (UNSW) Sydney, Darlinghurst, NSW 2010, Australia; .; St Vincent's Clinical School, Department of Medicine, UNSW Sydney, NSW 2052, Australia.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 08; Vol. 117 (36), pp. 22341-22350. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies*/chemistry
Antibodies*/genetics
Antibodies*/metabolism
Autoantigens*/chemistry
Autoantigens*/metabolism
Antibody Diversity/*genetics
Gene Rearrangement, B-Lymphocyte/*genetics
Mutation/*genetics
Animals ; Antibody Affinity/genetics ; Autoantibodies/chemistry ; Autoantibodies/genetics ; Autoantibodies/metabolism ; Complementarity Determining Regions/genetics ; Immunity, Humoral/genetics ; Mice ; Models, Molecular ; Protein Conformation ; Somatic Hypermutation, Immunoglobulin/genetics
Czasopismo naukowe
Tytuł :
Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers.
Autorzy :
Shin JJH; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK. .
Crook OM; The Milner Therapeutics Institute, University of Cambridge, Cambridge, CB2 0AW, UK.; Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QR, UK.; MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, CB2 0SR, UK.
Borgeaud AC; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
Cattin-Ortolá J; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
Peak-Chew SY; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
Breckels LM; Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QR, UK.
Gillingham AK; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
Chadwick J; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
Lilley KS; The Milner Therapeutics Institute, University of Cambridge, Cambridge, CB2 0AW, UK.; Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QR, UK.
Munro S; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK. .
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Źródło :
Nature communications [Nat Commun] 2020 Nov 25; Vol. 11 (1), pp. 5987. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autoantigens/*metabolism
Golgi Matrix Proteins/*metabolism
Membrane Proteins/*metabolism
trans-Golgi Network/*metabolism
Autoantigens/genetics ; Endosomes/metabolism ; Gene Knockdown Techniques ; Golgi Matrix Proteins/genetics ; HEK293 Cells ; HeLa Cells ; Humans ; Mitochondria/metabolism ; Proteomics/methods ; Spatial Analysis
Czasopismo naukowe
Tytuł :
A Circle RNA Regulatory Axis Promotes Lung Squamous Metastasis via CDR1-Mediated Regulation of Golgi Trafficking.
Autorzy :
Harrison EB; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.; Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina.
Porrello A; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
Bowman BM; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
Belanger AR; Division of Pulmonary and Critical Care Medicine, University of North Carolina, Chapel Hill, North Carolina.
Yacovone G; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
Azam SH; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
Windham IA; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, North Carolina.
Ghosh SK; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
Wang M; Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina.
Mckenzie N; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
Waugh TA; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
Van Swearingen AED; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
Cohen SM; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
Allen DG; Marsico Lung Institute/Cystic Fibrosis Center, University of North Carolina, Chapel Hill, North Carolina.
Goodwin TJ; Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina.
Mascenik T; Marsico Lung Institute/Cystic Fibrosis Center, University of North Carolina, Chapel Hill, North Carolina.
Bear JE; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, North Carolina.
Cohen S; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, North Carolina.
Randell SH; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, North Carolina.; Marsico Lung Institute/Cystic Fibrosis Center, University of North Carolina, Chapel Hill, North Carolina.
Massion PP; Vanderbilt Ingram Cancer Center, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Major MB; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
Huang L; Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina.
Pecot CV; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina. .; Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina.; Division of Hematology & Oncology, University of North Carolina, Chapel Hill, North Carolina.; Department of Medicine, University of North Carolina, Chapel Hill, North Carolina.
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Źródło :
Cancer research [Cancer Res] 2020 Nov 15; Vol. 80 (22), pp. 4972-4985. Date of Electronic Publication: 2020 Sep 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Autoantigens/*metabolism
Carcinoma, Squamous Cell/*secondary
Golgi Apparatus/*metabolism
Lung Neoplasms/*pathology
Nerve Tissue Proteins/*metabolism
RNA, Circular/*antagonists & inhibitors
RNA, Long Noncoding/*metabolism
Adaptor Protein Complex 1/metabolism ; Animals ; Autoantigens/genetics ; Carcinoma, Squamous Cell/metabolism ; Carcinoma, Squamous Cell/mortality ; Cell Line, Tumor ; Cell Movement/physiology ; Coat Protein Complex I/metabolism ; Endoplasmic Reticulum/metabolism ; Female ; Humans ; Hyaluronic Acid/therapeutic use ; Lung Neoplasms/metabolism ; Lung Neoplasms/mortality ; Mice ; Mice, Nude ; MicroRNAs/metabolism ; Nanoparticles/therapeutic use ; Neoplasm Metastasis ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Nerve Tissue Proteins/genetics
Czasopismo naukowe
Tytuł :
Clinical significance of IgG antimitochondrial M2 antibody levels in primary biliary cholangitis: A single center study from China.
Autorzy :
Feng L; Department of Hepatology, The First Hospital of Jilin University, Changchun, China.
Dong K; Department of Gastroenterology, Yantaishan Hospital, Shandong, China.
Zhang X; Department of Hepatology, The First Hospital of Jilin University, Changchun, China.
Ma B; Department of Hepatology, The First Hospital of Jilin University, Changchun, China.
Chen L; Department of Hepatology, The First Hospital of Jilin University, Changchun, China.
Yang Q; Department of Hepatology, The First Hospital of Jilin University, Changchun, China.
Chen Q; Department of Hepatology, The First Hospital of Jilin University, Changchun, China.
Wen X; Department of Hepatology, The First Hospital of Jilin University, Changchun, China.
Jin Q; Department of Hepatology, The First Hospital of Jilin University, Changchun, China.
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Źródło :
PloS one [PLoS One] 2020 Nov 12; Vol. 15 (11), pp. e0242164. Date of Electronic Publication: 2020 Nov 12 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autoantigens/*immunology
Immunoglobulin G/*immunology
Liver Cirrhosis, Biliary/*immunology
Mitochondrial Proteins/*immunology
Aged ; Autoantigens/blood ; Biomarkers/blood ; Female ; Humans ; Immunoglobulin G/blood ; Liver Cirrhosis, Biliary/pathology ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Distinct Phenotypes of Islet Antigen-Specific CD4+ T Cells Among the 3 Subtypes of Type 1 Diabetes.
Autorzy :
Chujo D; Center for Clinical Research, Toyama University Hospital, Toyama, Japan.; Islet Cell Transplantation Project, National Center for Global Health and Medicine, Tokyo, Japan.; Department of Diabetes, Endocrinology, and Metabolism, National Center for Global Health and Medicine, Tokyo, Japan.; Department of Internal Medicine (I), Toyama University Hospital, Toyama, Japan.
Kawabe A; Islet Cell Transplantation Project, National Center for Global Health and Medicine, Tokyo, Japan.
Matsushita M; Department of Diabetes, Endocrinology, and Metabolism, National Center for Global Health and Medicine, Tokyo, Japan.
Takahashi N; Department of Diabetes, Endocrinology, and Metabolism, National Center for Global Health and Medicine, Tokyo, Japan.
Tsutsumi C; Department of Internal Medicine (I), Osaka Medical College, Takatsuki, Japan.
Haseda F; Department of Internal Medicine (I), Osaka Medical College, Takatsuki, Japan.
Imagawa A; Department of Internal Medicine (I), Osaka Medical College, Takatsuki, Japan.
Hanafusa T; Department of Internal Medicine (I), Osaka Medical College, Takatsuki, Japan.; Sakai City Medical Center, Sakai, Japan.
Ueki K; Department of Diabetes, Endocrinology, and Metabolism, National Center for Global Health and Medicine, Tokyo, Japan.; Diabetes Research Center, National Center for Global Health and Medicine, Tokyo, Japan.
Kajio H; Department of Diabetes, Endocrinology, and Metabolism, National Center for Global Health and Medicine, Tokyo, Japan.
Yagi K; Department of Internal Medicine (I), Toyama University Hospital, Toyama, Japan.
Tobe K; Center for Clinical Research, Toyama University Hospital, Toyama, Japan.; Department of Internal Medicine (I), Toyama University Hospital, Toyama, Japan.
Shimoda M; Islet Cell Transplantation Project, National Center for Global Health and Medicine, Tokyo, Japan.
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2020 Oct 01; Vol. 105 (10).
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunity, Cellular*
Autoantigens/*immunology
CD4-Positive T-Lymphocytes/*immunology
Diabetes Mellitus, Type 1/*diagnosis
Islets of Langerhans/*immunology
Adolescent ; Adult ; Age of Onset ; Aged ; Autoantigens/metabolism ; Chemokine CXCL10/immunology ; Chemokine CXCL10/metabolism ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 1/immunology ; Disease Progression ; Female ; Glutamate Decarboxylase/immunology ; Glutamate Decarboxylase/metabolism ; HLA-DR Serological Subtypes/immunology ; HLA-DR Serological Subtypes/metabolism ; Humans ; Immunoassay ; Insulin/immunology ; Insulin/metabolism ; Interleukin-6/immunology ; Interleukin-6/metabolism ; Islets of Langerhans/metabolism ; Male ; Middle Aged ; Protein Precursors/immunology ; Protein Precursors/metabolism ; Severity of Illness Index ; Up-Regulation/immunology ; Young Adult
Czasopismo naukowe
Tytuł :
Potential antigenic cross-reactivity between SARS-CoV-2 and human tissue with a possible link to an increase in autoimmune diseases.
Autorzy :
Vojdani A; Immunosciences Lab, Inc, 822 S. Robertson Blvd, Ste. 312, Los Angeles, CA 90035, USA; Department of Preventive Medicine, Loma Linda University, Loma Linda, CA 92350, USA. Electronic address: .
Kharrazian D; Department of Preventive Medicine, Loma Linda University, Loma Linda, CA 92350, USA; Harvard Medical School, 25 Shattuck St, Boston, MA 02115, USA. Electronic address: .
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Źródło :
Clinical immunology (Orlando, Fla.) [Clin Immunol] 2020 Aug; Vol. 217, pp. 108480. Date of Electronic Publication: 2020 May 24.
Typ publikacji :
Letter
MeSH Terms :
Pandemics*/prevention & control
Autoantibodies/*immunology
Autoantigens/*immunology
Autoimmune Diseases/*epidemiology
Betacoronavirus/*immunology
Coronavirus Infections/*epidemiology
Nucleocapsid Proteins/*immunology
Pneumonia, Viral/*epidemiology
Spike Glycoprotein, Coronavirus/*immunology
Antibodies, Viral/chemistry ; Antibodies, Viral/genetics ; Autoantibodies/chemistry ; Autoantibodies/genetics ; Autoantigens/chemistry ; Autoantigens/genetics ; Autoimmune Diseases/etiology ; Autoimmune Diseases/immunology ; Autoimmune Diseases/virology ; Autoimmunity ; Betacoronavirus/pathogenicity ; COVID-19 ; COVID-19 Vaccines ; Coronavirus Infections/immunology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/virology ; Coronavirus Nucleocapsid Proteins ; Cross Reactions ; Gene Expression ; Host-Pathogen Interactions/genetics ; Host-Pathogen Interactions/immunology ; Humans ; Immunity, Innate ; Nucleocapsid Proteins/chemistry ; Nucleocapsid Proteins/genetics ; Phosphoproteins ; Pneumonia, Viral/immunology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/virology ; Pulmonary Surfactant-Associated Proteins/antagonists & inhibitors ; Pulmonary Surfactant-Associated Proteins/genetics ; Pulmonary Surfactant-Associated Proteins/immunology ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics ; Viral Vaccines/adverse effects ; Viral Vaccines/biosynthesis
Opinia redakcyjna
Tytuł :
Co-occurrence of IgE and IgG autoantibodies in patients with chronic spontaneous urticaria.
Autorzy :
Asero R; Ambulatorio di Allergologia, Clinica San Carlo, Paderno Dugnano, Italy.
Marzano AV; UOC Dermatologia, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi di Milano, Milan, Italy.
Ferrucci S; UOC Dermatologia, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Lorini M; Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano, Milan, Italy.
Carbonelli V; Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano, Milan, Italy.
Cugno M; Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi di Milano, Milan, Italy.; Medicina Interna, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
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Źródło :
Clinical and experimental immunology [Clin Exp Immunol] 2020 Jun; Vol. 200 (3), pp. 242-249. Date of Electronic Publication: 2020 Mar 17.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Autoantibodies*/blood
Autoantibodies*/immunology
Autoantigens*/blood
Autoantigens*/immunology
Chronic Urticaria*/blood
Chronic Urticaria*/drug therapy
Chronic Urticaria*/immunology
Immunoglobulin E*/blood
Immunoglobulin E*/immunology
Immunoglobulin G*/blood
Immunoglobulin G*/immunology
Omalizumab/*administration & dosage
Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Lectins, C-Type/blood ; Lectins, C-Type/immunology ; Male ; Middle Aged ; Receptors, IgE/blood ; Receptors, IgE/immunology ; Thromboplastin/immunology ; Thromboplastin/metabolism ; Thyroglobulin/blood ; Thyroglobulin/immunology
Czasopismo naukowe
Tytuł :
GOLGA4, A Golgi matrix protein, is dispensable for spermatogenesis and male fertility in mice.
Autorzy :
Guo S; Institute Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
Chunyu Lv; Institute Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
Ouyang S; Institute Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
Wang X; Institute Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
Liao A; Institute Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
Yuan S; Institute Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China; Shenzhen Huazhong University of Science and Technology Research Institute, Shenzhen, Guangdong, 518057, China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Aug 27; Vol. 529 (3), pp. 642-646. Date of Electronic Publication: 2020 Jul 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autoantigens/*genetics
Fertility/*genetics
Gene Expression Profiling/*methods
Golgi Matrix Proteins/*genetics
Spermatogenesis/*genetics
Animals ; Autoantigens/metabolism ; Base Sequence ; Female ; Golgi Matrix Proteins/metabolism ; Humans ; Liver/metabolism ; Male ; Mice, Knockout ; Ovary/metabolism ; Stomach/chemistry ; Testis/metabolism
Czasopismo naukowe
Tytuł :
The REGγ inhibitor NIP30 increases sensitivity to chemotherapy in p53-deficient tumor cells.
Autorzy :
Gao X; East China Normal University and Shanghai Changzheng Hospital Joint Research Center for Orthopedic Oncology, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China.; Department of Orthopedic Oncology, Changzheng Hospital, The Second Military Medical University, 415 Fengyang Road, 200003, Shanghai, China.; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China.
Wang Q; Department of Surgery, Department of Physiology & Cell Biology, College of Medicine, Davis Heart and Lung Research Institute, Wexner Medical Center, The Ohio State University, Columbus, OH, 43210, USA.
Wang Y; The Institute of Aging Research, School of Medicine, Hangzhou Normal University, 310036, Hangzhou, Zhejiang, China.
Liu J; The Institute of Aging Research, School of Medicine, Hangzhou Normal University, 310036, Hangzhou, Zhejiang, China.
Liu S; Department of Hematology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong Province, P. R. China.
Liu J; Reproductive & Developmental Biology Laboratory, National Institute of Environmental Health Sciences (NIEHS), Research Triangle Prk, NC, 27709, USA.
Zhou X; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China.
Zhou L; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China.
Chen H; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China.
Pan L; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China.
Chen J; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China.
Wang D; East China Normal University and Shanghai Changzheng Hospital Joint Research Center for Orthopedic Oncology, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China.; Department of Orthopedic Oncology, Changzheng Hospital, The Second Military Medical University, 415 Fengyang Road, 200003, Shanghai, China.
Zhang Q; Department of Hematology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong Province, P. R. China.
Shen S; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China.
Xiao Y; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China.
Wu Z; East China Normal University and Shanghai Changzheng Hospital Joint Research Center for Orthopedic Oncology, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China.; Department of Orthopedic Oncology, Changzheng Hospital, The Second Military Medical University, 415 Fengyang Road, 200003, Shanghai, China.
Cheng Y; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China.
Chen G; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China.
Kubra S; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China.
Qin J; The Joint Laboratory of Translational Medicine, National Center for Protein Sciences (Beijing) and Peking University Cancer Hospital, State Key Laboratory of Proteomics, Institute of Lifeomics, 102206, Beijing, China.
Huang L; Department of Physiology and Biophysics, University of California, Irvine, CA, 92697, USA.
Zhang P; Department of Pathology, The Second Chengdu Municipal Hospital, 610017, Chengdu, China.
Wang C; Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Moses RE; Department of Molecular and Cellular Biology, Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.
Lonard DM; Department of Molecular and Cellular Biology, Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.
Malley BWO; Department of Molecular and Cellular Biology, Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.
Fares F; Department of Human Biology. Faculty of Natural Sciences, University of Haifa, Haifa, 3498838, Israel.
Zhang B; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China. .
Li X; East China Normal University and Shanghai Changzheng Hospital Joint Research Center for Orthopedic Oncology, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China. .; Department of Molecular and Cellular Biology, Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA. .
Li L; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China. .
Xiao J; East China Normal University and Shanghai Changzheng Hospital Joint Research Center for Orthopedic Oncology, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, China. .; Department of Orthopedic Oncology, Changzheng Hospital, The Second Military Medical University, 415 Fengyang Road, 200003, Shanghai, China. .
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Źródło :
Nature communications [Nat Commun] 2020 Aug 06; Vol. 11 (1), pp. 3904. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Autoantigens/*metabolism
Intracellular Signaling Peptides and Proteins/*metabolism
Nuclear Proteins/*metabolism
Proteasome Endopeptidase Complex/*metabolism
Proteasome Inhibitors/*metabolism
Tumor Suppressor Protein p53/*deficiency
Animals ; Autoantigens/genetics ; Cell Cycle ; Cell Line, Tumor ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; Drug Resistance, Neoplasm ; HEK293 Cells ; Heterografts ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; Mice ; Mice, Knockout ; Nuclear Proteins/genetics ; Phosphorylation ; Proteasome Endopeptidase Complex/deficiency ; Proteasome Endopeptidase Complex/genetics ; Tumor Suppressor Protein p53/genetics ; cdc25 Phosphatases/metabolism
Czasopismo naukowe
Tytuł :
Inflammation-Induced Abnormal Expression of Self-molecules on Epithelial Cells: Targets for Tumor Immunoprevention.
Autorzy :
Jacqueline C; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Lee A; Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania.
Frey N; Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania.
Minden JS; Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania.
Finn OJ; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. .
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Źródło :
Cancer immunology research [Cancer Immunol Res] 2020 Aug; Vol. 8 (8), pp. 1027-1038. Date of Electronic Publication: 2020 May 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Antigens, Neoplasm/*immunology
Autoantigens/*immunology
Cancer Vaccines/*immunology
Epithelial Cells/*immunology
Neoplasms/*immunology
Neoplasms/*metabolism
Autoantigens/metabolism ; Cancer Vaccines/pharmacology ; Cells, Cultured ; Epithelial Cells/metabolism ; Healthy Volunteers ; Humans ; Inflammation/immunology ; Inflammation/metabolism ; Inflammation/pathology ; Leukocytes, Mononuclear/immunology ; Macrophages/immunology ; Macrophages/metabolism ; Monitoring, Immunologic/methods ; Neoplasms/pathology ; Neoplasms/therapy ; Proteomics/methods
Czasopismo naukowe
Tytuł :
Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells.
Autorzy :
Li H; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Adamopoulos IE; Division of Rheumatology, Allergy and Clinical Immunology, University of California, Davis, CA, 95817, USA.
Moulton VR; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Stillman IE; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02115, USA.
Herbert Z; Molecular Biology Core Facilities, Dana-Farber Cancer Institute, 21-27 Burlington Ave, Boston, MA, 02215, USA.
Moon JJ; Center for Immunology and inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
Sharabi A; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Krishfield S; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Tsokos MG; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Tsokos GC; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Jun 05; Vol. 11 (1), pp. 2859. Date of Electronic Publication: 2020 Jun 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Autoantigens/*immunology
Interleukin-17/*metabolism
Lupus Erythematosus, Systemic/*immunology
T-Lymphocyte Subsets/*immunology
Adoptive Transfer ; Animals ; Autoantigens/metabolism ; Disease Models, Animal ; Disease Progression ; Female ; Humans ; Immune Tolerance ; Ki-67 Antigen/immunology ; Ki-67 Antigen/metabolism ; Lupus Erythematosus, Systemic/blood ; Macrophages/immunology ; Mice ; Mice, Knockout ; Receptors, Antigen, T-Cell, alpha-beta/metabolism ; T-Lymphocyte Subsets/metabolism
Czasopismo naukowe
Tytuł :
Identification of two major autoantigens negatively regulating endothelial activation in Takayasu arteritis.
Autorzy :
Mutoh T; Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Shirai T; Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan. .
Ishii T; Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Shirota Y; Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Fujishima F; Department of Anatomic Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Takahashi F; Division of Medical Engineering, Department of Information Science, Iwate Medical University, Morioka, Japan.
Kakuta Y; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kanazawa Y; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Masamune A; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Saiki Y; Division of Cardiovascular Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Harigae H; Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Fujii H; Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
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Źródło :
Nature communications [Nat Commun] 2020 Mar 09; Vol. 11 (1), pp. 1253. Date of Electronic Publication: 2020 Mar 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autoantibodies/*metabolism
Autoantigens/*isolation & purification
Autoantigens/*metabolism
Endothelial Cells/*immunology
Takayasu Arteritis/*immunology
Takayasu Arteritis/*metabolism
Animals ; Autoantibodies/isolation & purification ; Autoantigens/genetics ; Autoantigens/immunology ; Cell Line, Tumor ; Cell Membrane/chemistry ; Cloning, Molecular ; Colitis, Ulcerative/immunology ; Disease Models, Animal ; Endothelial Protein C Receptor ; Endothelium, Vascular/metabolism ; Gene Library ; Humans ; Multiple Myeloma/metabolism ; Protein C/metabolism ; Rats ; Receptors, Endothelin/metabolism ; Scavenger Receptors, Class B/metabolism
Czasopismo naukowe
Tytuł :
Identification of antigenic epitopes of thyroperoxidase, thyroglobulin and interleukin-24. Exploration of cross-reactivity with environmental allergens and possible role in urticaria and hypothyroidism.
Autorzy :
Sánchez A; Medical Research Group (GINUMED) University Corporation Rafael Nuñez, Immunology Department, Faculty of medicine. Cartagena, Colombia; Group of Clinical and Experimental Allergy (GACE), IPS Universitaria, University of Antioquia. Medellín, Colombia.
Cardona R; Group of Clinical and Experimental Allergy (GACE), IPS Universitaria, University of Antioquia. Medellín, Colombia.
Munera M; Medical Research Group (GINUMED) University Corporation Rafael Nuñez, Immunology Department, Faculty of medicine. Cartagena, Colombia.
Sánchez J; Group of Clinical and Experimental Allergy (GACE), IPS Universitaria, University of Antioquia. Medellín, Colombia. Electronic address: .
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Źródło :
Immunology letters [Immunol Lett] 2020 Apr; Vol. 220, pp. 71-78. Date of Electronic Publication: 2020 Feb 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Allergens/*immunology
Autoantigens/*immunology
Chronic Urticaria/*immunology
Epitopes/*immunology
Hypothyroidism/*immunology
Interleukins/*immunology
Iodide Peroxidase/*immunology
Iron-Binding Proteins/*immunology
Thyroglobulin/*immunology
Animals ; Aspergillus fumigatus/immunology ; Autoantibodies/immunology ; Autoantigens/chemistry ; Autoantigens/classification ; Cats ; Cross Reactions ; Dogs ; Epitope Mapping ; Epitopes/chemistry ; Epitopes/classification ; Humans ; Interleukins/chemistry ; Interleukins/classification ; Iodide Peroxidase/chemistry ; Iodide Peroxidase/classification ; Iron-Binding Proteins/chemistry ; Iron-Binding Proteins/classification ; Models, Chemical ; Phylogeny ; Thyroglobulin/chemistry ; Thyroglobulin/classification
Czasopismo naukowe
Tytuł :
Sjögren syndrome/scleroderma autoantigen 1 is a direct Tankyrase binding partner in cancer cells.
Autorzy :
Perdreau-Dahl H; Membrane Transport Group, Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo, P.O. Box 1137 Blindern, 0318, Oslo, Norway.; Institute for Experimental Medical Research (IEMR), Oslo University Hospital, Ullevål PB 4956 Nydalen, NO-0424, Oslo, Norway.
Progida C; Centre for Immune Regulation, Department of Molecular Biosciences, University of Oslo, Blindernveien 31, 0371, Oslo, Norway.
Barfeld SJ; Prostate Cancer Group, Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo, P.O. Box 1137 Blindern, 0318, Oslo, Norway.
Guldsten H; Membrane Transport Group, Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo, P.O. Box 1137 Blindern, 0318, Oslo, Norway.
Thiede B; Department of Biosciences, University of Oslo, P.O. Box 1137 Blindern, 0316, Oslo, Norway.
Arntzen M; Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, P.O. Box 5003, N-1432, Ås, Norway.
Bakke O; Centre for Immune Regulation, Department of Molecular Biosciences, University of Oslo, Blindernveien 31, 0371, Oslo, Norway.
Mills IG; Prostate Cancer Group, Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo, P.O. Box 1137 Blindern, 0318, Oslo, Norway.; Patrick G Johnston Centre for Cancer Research, Queens University Belfast, Belfast, UK.; Nuffield Department of Surgical Sciences, Faculty of Medical Science, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Krauss S; Department of Immunology and Transfusion Medicine, Oslo University Hospital, and Hybrid Technology Hub-Centre of Excellence, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway.
Morth JP; Membrane Transport Group, Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo, P.O. Box 1137 Blindern, 0318, Oslo, Norway. .; Institute for Experimental Medical Research (IEMR), Oslo University Hospital, Ullevål PB 4956 Nydalen, NO-0424, Oslo, Norway. .; Enzyme and Protein Chemistry, Section for Protein Chemistry and Enzyme Technology, Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, 2800, Kgs. Lyngby, Denmark. .
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Źródło :
Communications biology [Commun Biol] 2020 Mar 13; Vol. 3 (1), pp. 123. Date of Electronic Publication: 2020 Mar 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autoantigens/*chemistry
Autoantigens/*metabolism
Neoplasms/*metabolism
Ribonucleoproteins/*chemistry
Ribonucleoproteins/*metabolism
Tankyrases/*chemistry
Tankyrases/*metabolism
Active Transport, Cell Nucleus/genetics ; Autoantigens/genetics ; Binding Sites ; Crystallography, X-Ray ; HeLa Cells ; Humans ; Neoplasms/pathology ; Nuclear Export Signals ; Phylogeny ; Protein Binding/genetics ; Protein Conformation, alpha-Helical ; Protein Domains ; Protein Interaction Maps/genetics ; Ribonucleoproteins/genetics ; Transfection
Czasopismo naukowe
Tytuł :
Serum Antibody and Glomerular Antigen of Antiphospholipase A2 Receptor in Chinese Patients with Idiopathic Membranous Nephropathy.
Autorzy :
Zhang QH; Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi 214000, China.
Wu M; Nanjing Medical University, Nanjing 211166, China.
Hu ZG; Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi 214000, China.
Liu XB; Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi 214000, China.
Huang B; School of Life Science, Zhejiang, Sci-Tech University, Hangzhou 310018, China.
Zhang Y; Jiangsu Institute of Nuclear Medicine, Wuxi 214063, China.
Liu B; Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi 214000, China.
Zhu YS; Nanjing Medical University, Nanjing 211166, China.
Wang L; Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi 214000, China.
Sun ZX; Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi 214000, China.
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Źródło :
BioMed research international [Biomed Res Int] 2020 May 08; Vol. 2020, pp. 1693710. Date of Electronic Publication: 2020 May 08 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Autoantibodies/*immunology
Autoantigens/*immunology
Glomerulonephritis, Membranous/*immunology
Receptors, Phospholipase A2/*immunology
Asian Continental Ancestry Group ; Autoantibodies/blood ; Autoantigens/blood ; Biomarkers/blood ; Creatinine/blood ; Glomerulonephritis, Membranous/blood ; Humans ; Kidney/immunology ; Kidney Glomerulus/immunology ; Proteinuria ; Retrospective Studies ; Serum Albumin/analysis
Czasopismo naukowe
Tytuł :
The Diagnostic Value of Antibodies Against Citrullinated or Carbamylated Fibrinogen in Rheumatoid Arthritis.
Autorzy :
Wang Z
Xue L
Xie J
Zhu N
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Źródło :
Clinical laboratory [Clin Lab] 2020 May 01; Vol. 66 (5).
Typ publikacji :
Journal Article
MeSH Terms :
Arthritis, Rheumatoid/*diagnosis
Autoantibodies/*blood
Autoantigens/*immunology
Fibrinogen/*immunology
Aged ; Autoantigens/chemistry ; Citrullination ; Enzyme-Linked Immunosorbent Assay ; Female ; Fibrinogen/chemistry ; Humans ; Male ; Middle Aged ; Peptides/chemistry ; Peptides/immunology ; Protein Carbamylation ; Sensitivity and Specificity
Czasopismo naukowe

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