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Wyszukujesz frazę ""autoantigens"" wg kryterium: Temat


Tytuł:
Spatiotemporal regulation of peripheral T cell tolerance.
Autorzy:
Brown CC
Rudensky AY
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Źródło:
Science (New York, N.Y.) [Science] 2023 May 05; Vol. 380 (6644), pp. 472-478. Date of Electronic Publication: 2023 May 04.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Peripheral Tolerance*
T-Lymphocytes*/immunology
Autoantigens ; Thymus Gland/cytology ; Humans ; Animals ; Mice
Czasopismo naukowe
Tytuł:
The adaptation model of immunity: Is the goal of central tolerance to eliminate defective T cells or self-reactive T cells?
Autorzy:
Manjili MH; Department of Microbiology & Immunology, VCU School of Medicine, VCU Massey Cancer Center, Richmond, Virginia, USA.
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Źródło:
Scandinavian journal of immunology [Scand J Immunol] 2022 Oct; Vol. 96 (4), pp. e13209. Date of Electronic Publication: 2022 Aug 10.
Typ publikacji:
Journal Article
MeSH Terms:
Central Tolerance*
T-Lymphocytes*
Aged ; Autoantigens ; Goals ; Humans ; Immune Tolerance ; Models, Immunological ; Thymus Gland
Czasopismo naukowe
Tytuł:
T Cell Mediated Conversion of a Non-Anti-La Reactive B Cell to an Autoreactive Anti-La B Cell by Somatic Hypermutation.
Autorzy:
Bachmann MP; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.; University Cancer Center (UCC), Tumor Immunology, University Hospital Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.; National Center for Tumor Diseases (NCT), 01307 Dresden, Germany.; German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Bartsch T; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.
Bippes CC; Institute of Immunology, Medical Faculty Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.
Bachmann D; University Cancer Center (UCC), Tumor Immunology, University Hospital Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.
Puentes-Cala E; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.; Corporación para la Investigación de la Corrosión (CIC), Piedecuesta, Santander 681011, Colombia.
Bachmann J; University Cancer Center (UCC), Tumor Immunology, University Hospital Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.
Bartsch H; Institute of Immunology, Medical Faculty Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.
Arndt C; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.
Koristka S; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.
Loureiro LR; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.
Kegler A; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.
Laube M; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.
Gross JK; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Gross T; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Kurien BT; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Scofield RH; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Farris AD; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
James JA; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Schmitz M; National Center for Tumor Diseases (NCT), 01307 Dresden, Germany.; German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; Institute of Immunology, Medical Faculty Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.
Feldmann A; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 26; Vol. 22 (3). Date of Electronic Publication: 2021 Jan 26.
Typ publikacji:
Journal Article
MeSH Terms:
Somatic Hypermutation, Immunoglobulin*
Autoantigens/*immunology
Autoimmunity/*genetics
B-Lymphocytes/*immunology
B-Lymphocytes/*metabolism
Cell Communication/*immunology
Ribonucleoproteins/*immunology
T-Lymphocytes/*immunology
3T3 Cells ; Adoptive Transfer ; Amino Acid Sequence ; Animals ; Antibody Specificity/genetics ; Autoantibodies/chemistry ; Autoantibodies/genetics ; Autoantibodies/immunology ; Autoantigens/chemistry ; Autoimmune Diseases/genetics ; Autoimmune Diseases/immunology ; Autoimmune Diseases/metabolism ; Disease Models, Animal ; Epitope Mapping ; Epitopes/chemistry ; Epitopes/immunology ; Fluorescent Antibody Technique ; Germ Cells/metabolism ; Humans ; Immunization ; Mice ; Mice, Transgenic ; Models, Molecular ; Protein Conformation ; Ribonucleoproteins/chemistry ; T-Lymphocytes/metabolism ; SS-B Antigen
Czasopismo naukowe
Tytuł:
Positive selection of immune repertoires: A short further history.
Autorzy:
Forsdyke DR; Department of Biomedical and Molecular, Sciences, Queen's University, Kingston, Ontario, Canada.
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Źródło:
Scandinavian journal of immunology [Scand J Immunol] 2022 Apr; Vol. 95 (4), pp. e13144. Date of Electronic Publication: 2022 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Autoimmune Diseases*
T-Lymphocytes*
Autoantigens ; Humans
Czasopismo naukowe
Tytuł:
T cell-mediated autoimmunity in immune thrombocytopenia.
Autorzy:
Vrbensky JR; Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
Nazy I; Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.; McMaster Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada.
Clare R; Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
Larché M; Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
Arnold DM; Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.; McMaster Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada.; Canadian Blood Services, Hamilton, ON, Canada.
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Źródło:
European journal of haematology [Eur J Haematol] 2022 Jan; Vol. 108 (1), pp. 18-27. Date of Electronic Publication: 2021 Sep 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Autoimmunity*
Disease Susceptibility*/immunology
Purpura, Thrombocytopenic, Idiopathic/*etiology
T-Lymphocytes/*immunology
Apoptosis/genetics ; Apoptosis/immunology ; Autoantibodies/immunology ; Autoantigens/immunology ; Biomarkers ; Blood Platelets/immunology ; Blood Platelets/metabolism ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/metabolism ; Cytotoxicity, Immunologic ; Disease Management ; Gene Expression Regulation ; Genes, MHC Class I ; Humans ; Lymphocyte Activation/immunology ; Purpura, Thrombocytopenic, Idiopathic/diagnosis ; Purpura, Thrombocytopenic, Idiopathic/therapy ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł:
Mining the capacity of human-associated microorganisms to trigger rheumatoid arthritis-A systematic immunoinformatics analysis of T cell epitopes.
Autorzy:
Repac J; Institute of Physiology and Biochemistry 'Ivan Djaja', Faculty of Biology, University of Belgrade, Belgrade, Serbia.
Mandić M; Institute of Physiology and Biochemistry 'Ivan Djaja', Faculty of Biology, University of Belgrade, Belgrade, Serbia.
Lunić T; Institute of Physiology and Biochemistry 'Ivan Djaja', Faculty of Biology, University of Belgrade, Belgrade, Serbia.
Božić B; Institute of Physiology and Biochemistry 'Ivan Djaja', Faculty of Biology, University of Belgrade, Belgrade, Serbia.
Božić Nedeljković B; Institute of Physiology and Biochemistry 'Ivan Djaja', Faculty of Biology, University of Belgrade, Belgrade, Serbia.
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Źródło:
PloS one [PLoS One] 2021 Jun 29; Vol. 16 (6), pp. e0253918. Date of Electronic Publication: 2021 Jun 29 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Arthritis, Rheumatoid/*immunology
Autoimmune Diseases/*immunology
Leukocytes, Mononuclear/*immunology
T-Lymphocytes/*immunology
Arthritis, Rheumatoid/microbiology ; Autoantigens/genetics ; Autoantigens/immunology ; Autoimmune Diseases/microbiology ; Autoimmune Diseases/pathology ; Autoimmunity/genetics ; Autoimmunity/immunology ; Epitopes, T-Lymphocyte/genetics ; Female ; Humans ; Leukocytes, Mononuclear/microbiology ; Male ; T-Lymphocytes/microbiology ; T-Lymphocytes/pathology
Czasopismo naukowe
Tytuł:
T cell responses to peptides of Goodpasture autoantigen in patients with anti-glomerular basement membrane disease.
Autorzy:
Hu SY; Renal Division, Peking University First Hospital; Institute of Nephrology, Peking University; Key Laboratory of Renal Disease, Ministry of Health of China; Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.; Department of Nephrology, Tianjin Medical University General Hospital, Tianjin, China.
Jia XY; Renal Division, Peking University First Hospital; Institute of Nephrology, Peking University; Key Laboratory of Renal Disease, Ministry of Health of China; Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.
Gu QH; Renal Division, Peking University First Hospital; Institute of Nephrology, Peking University; Key Laboratory of Renal Disease, Ministry of Health of China; Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.
Yu CY; Renal Division, Peking University First Hospital; Institute of Nephrology, Peking University; Key Laboratory of Renal Disease, Ministry of Health of China; Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.
Cheng XY; Renal Division, Peking University First Hospital; Institute of Nephrology, Peking University; Key Laboratory of Renal Disease, Ministry of Health of China; Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.
Jin QZ; Renal Division, Peking University First Hospital; Institute of Nephrology, Peking University; Key Laboratory of Renal Disease, Ministry of Health of China; Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.
Zhou FD; Renal Division, Peking University First Hospital; Institute of Nephrology, Peking University; Key Laboratory of Renal Disease, Ministry of Health of China; Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.
Cui Z; Renal Division, Peking University First Hospital; Institute of Nephrology, Peking University; Key Laboratory of Renal Disease, Ministry of Health of China; Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.
Zhao MH; Renal Division, Peking University First Hospital; Institute of Nephrology, Peking University; Key Laboratory of Renal Disease, Ministry of Health of China; Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.; Peking-Tsinghua Center for Life Sciences, Beijing, China.
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Źródło:
Nephrology (Carlton, Vic.) [Nephrology (Carlton)] 2018 Apr; Vol. 23 (4), pp. 345-350.
Typ publikacji:
Journal Article
MeSH Terms:
Autoimmunity*
Immunity, Cellular*
Immunodominant Epitopes*
Anti-Glomerular Basement Membrane Disease/*immunology
Autoantigens/*immunology
Collagen Type IV/*immunology
Peptide Fragments/*immunology
T-Lymphocytes/*immunology
Adult ; Anti-Glomerular Basement Membrane Disease/blood ; Autoantigens/blood ; B-Lymphocytes/immunology ; B-Lymphocytes/metabolism ; Case-Control Studies ; Cell Proliferation ; Cells, Cultured ; Collagen Type IV/blood ; Epitope Mapping ; Female ; Humans ; Lymphocyte Activation ; Male ; Middle Aged ; T-Lymphocytes/metabolism ; Young Adult
Czasopismo naukowe
Tytuł:
On T cell development, T cell signals, T cell specificity and sensitivity, and the autoimmunity facilitated by lymphopenia.
Autorzy:
Bretscher PA; Department of Biochemistry, Microbiology, and Immunology, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Al-Yassin G; Department of Biochemistry, Microbiology, and Immunology, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Anderson CC; Department of Surgery, Alberta Diabetes Institute, Alberta Transplant Institute, University of Alberta, Edmonton, AB, Canada.; Department of Medical Microbiology & Immunology, Alberta Diabetes Institute, Alberta Transplant Institute, University of Alberta, Edmonton, AB, Canada.
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Źródło:
Scandinavian journal of immunology [Scand J Immunol] 2020 Jun; Vol. 91 (6), pp. e12888. Date of Electronic Publication: 2020 May 07.
Typ publikacji:
Journal Article
MeSH Terms:
T-Cell Antigen Receptor Specificity*
Lymphopenia/*immunology
T-Lymphocytes/*immunology
Animals ; Antigen Presentation ; Autoantigens/immunology ; Autoantigens/metabolism ; Autoimmunity ; Cell Communication ; Cell Differentiation ; Cell Survival ; Histocompatibility Antigens/metabolism ; Humans ; Lymphocyte Activation ; Models, Immunological ; Peptide Fragments/immunology ; Peptide Fragments/metabolism ; Receptors, Antigen, T-Cell/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
Approaches to inducing antigen-specific immune tolerance in allergy and autoimmunity: Focus on antigen-presenting cells and extracellular vesicles.
Autorzy:
Nazimek K; Jagiellonian University Medical College, Department of Immunology, Krakow, Poland.
Bryniarski K; Jagiellonian University Medical College, Department of Immunology, Krakow, Poland.
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Źródło:
Scandinavian journal of immunology [Scand J Immunol] 2020 Jun; Vol. 91 (6), pp. e12881. Date of Electronic Publication: 2020 May 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Autoimmune Diseases/*immunology
B-Lymphocytes/*immunology
Extracellular Vesicles/*immunology
Hypersensitivity/*immunology
T-Lymphocytes/*immunology
Animals ; Autoantigens/immunology ; Autoimmunity ; Epitopes ; Humans ; Lymphocyte Activation ; T-Cell Antigen Receptor Specificity
Czasopismo naukowe
Tytuł:
B cell tolerance to epidermal ribonuclear-associated neo-autoantigen in vivo.
Autorzy:
Degn SE; Program in Cellular and Molecular Medicine, Boston Children's Hospital, and Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Department of Biomedicine, Aarhus University, Aarhus C, Denmark.
Alicot E; Program in Cellular and Molecular Medicine, Boston Children's Hospital, and Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
Carroll MC; Program in Cellular and Molecular Medicine, Boston Children's Hospital, and Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
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Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2018 Feb; Vol. 191 (2), pp. 151-165. Date of Electronic Publication: 2017 Nov 20.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Autoantigens/*genetics
B-Lymphocytes/*immunology
Epitopes, B-Lymphocyte/*immunology
Epitopes, T-Lymphocyte/*immunology
Lupus Erythematosus, Systemic/*immunology
RNA/*immunology
T-Lymphocytes/*immunology
Animals ; Autoantibodies/metabolism ; Autoantigens/immunology ; Cell Communication ; Complement C4/genetics ; Epidermis/immunology ; Epitopes, B-Lymphocyte/genetics ; Epitopes, T-Lymphocyte/genetics ; Humans ; Immune Tolerance ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; RNA/genetics
Czasopismo naukowe
Tytuł:
The susceptible HLA class II alleles and their presenting epitope(s) in Goodpasture's disease.
Autorzy:
Xie LJ; Renal Division, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.; Renal Division, Department of Medicine, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China.
Cui Z; Renal Division, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.
Chen FJ; State Key Laboratory for Structural Chemistry of Unstable and Stable Species, BNLMS, College of Chemistry and Molecular Engineering and Center for Theoretical Biology, Peking University, Beijing, China.
Pei ZY; Beijing Computing Center, Beijing, China.
Hu SY; Renal Division, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.
Gu QH; Renal Division, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.
Jia XY; Renal Division, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.
Zhu L; Renal Division, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.
Zhou XJ; Renal Division, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.
Zhang H; Renal Division, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.
Liao YH; Renal Division, Department of Medicine, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China.
Lai LH; State Key Laboratory for Structural Chemistry of Unstable and Stable Species, BNLMS, College of Chemistry and Molecular Engineering and Center for Theoretical Biology, Peking University, Beijing, China.
Hudson BG; Department of Biochemistry, Division of Nephrology and Hypertention, Department of Medicine, Center for Matrix Biology, Aspirnaut Program, Department of Pathology, Microbiology, and Immunology, Department of Cell and Developmental Biology, Vanderbilt Ingram Cancer Centger, Vanderbilt Imstitute of Chemical Biology, Vanderbilt University Medical Center, Nashville, TN, USA.
Zhao MH; Renal Division, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China.; Peking-Tsinghua Center for Life Sciences, Beijing, China.
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Źródło:
Immunology [Immunology] 2017 Aug; Vol. 151 (4), pp. 395-404. Date of Electronic Publication: 2017 May 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Glomerular Basement Membrane Disease/*immunology
Autoantigens/*metabolism
Collagen Type IV/*metabolism
Epitopes, T-Lymphocyte/*metabolism
HLA-DRB1 Chains/*metabolism
T-Lymphocytes/*immunology
Alleles ; Autoantigens/genetics ; China ; Collagen Type IV/genetics ; Computer Simulation ; Epitope Mapping ; Epitopes, T-Lymphocyte/genetics ; Genetic Predisposition to Disease ; Genotype ; HLA-DRB1 Chains/genetics ; Humans ; Polymorphism, Genetic ; Protein Binding ; Protein Conformation ; Receptors, Antigen, T-Cell/metabolism ; Risk
Czasopismo naukowe
Tytuł:
Dendritic cells, T cells and their interaction in rheumatoid arthritis.
Autorzy:
Wehr P; The University of Queensland Diamantina Institute, Translational Research Institute, Princess Alexandra Hospital, Brisbane, Australia.
Purvis H; King's College London, Academic Department of Rheumatology, Centre for Inflammation Biology and Cancer Immunology, School of Immunology and Microbial Sciences, Faculty of Life Sciences and Medicine, London, UK.
Law SC; The University of Queensland Diamantina Institute, Translational Research Institute, Princess Alexandra Hospital, Brisbane, Australia.
Thomas R; The University of Queensland Diamantina Institute, Translational Research Institute, Princess Alexandra Hospital, Brisbane, Australia.
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Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2019 Apr; Vol. 196 (1), pp. 12-27. Date of Electronic Publication: 2019 Jan 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Arthritis, Rheumatoid/*immunology
B-Lymphocytes/*immunology
Dendritic Cells/*immunology
Immunotherapy/*methods
T-Lymphocytes/*immunology
Animals ; Antibody Formation ; Antigen Presentation ; Autoantigens/immunology ; Autoantigens/metabolism ; Autoimmunity ; Cell Communication ; Humans ; Immune Tolerance ; Lymphocyte Activation ; Peptides/immunology ; Peptides/metabolism
Czasopismo naukowe
Tytuł:
Atherosclerosis: Beyond the lipid storage hypothesis. The role of autoimmunity.
Autorzy:
Cinoku II; Department of Physiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Mavragani CP; Department of Physiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.; Department of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Moutsopoulos HM; Department of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.; Academy of Athens, Athens, Greece.
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Źródło:
European journal of clinical investigation [Eur J Clin Invest] 2020 Feb; Vol. 50 (2), pp. e13195. Date of Electronic Publication: 2020 Jan 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Atherosclerosis/*immunology
Autoantibodies/*immunology
Autoimmunity/*immunology
Cytokines/*immunology
Inflammation/*immunology
Plaque, Atherosclerotic/*immunology
T-Lymphocytes/*immunology
Adaptive Immunity/immunology ; Adoptive Transfer ; Animals ; Atherosclerosis/drug therapy ; Atherosclerosis/metabolism ; Autoantigens/immunology ; Disease Models, Animal ; Endothelial Cells/immunology ; Heat-Shock Proteins/immunology ; Humans ; Immunity, Innate/immunology ; Immunologic Factors/therapeutic use ; Immunosuppressive Agents/therapeutic use ; Lipoproteins, LDL/immunology ; Macrophages/immunology ; Neutrophils/immunology ; T-Lymphocytes/transplantation ; Vaccination ; beta 2-Glycoprotein I/immunology
Czasopismo naukowe
Tytuł:
On certain two-signal perspectives of lymphocyte activation and inactivation, thymic G-quadruplexes, and the role of aggregation in self/not-self discrimination.
Autorzy:
Forsdyke DR; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
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Źródło:
Scandinavian journal of immunology [Scand J Immunol] 2019 Oct; Vol. 90 (4), pp. e12797. Date of Electronic Publication: 2019 Jun 21.
Typ publikacji:
Journal Article
MeSH Terms:
Models, Immunological*
Receptor Aggregation*
T-Lymphocytes/*physiology
Thymus Gland/*immunology
Adaptive Immunity ; Animals ; Autoantigens/immunology ; Autoimmunity ; Consensus ; G-Quadruplexes ; Humans ; Immunity, Innate ; Lymphocyte Activation ; Self Tolerance
Czasopismo naukowe
Tytuł:
Two signal half-century: From negative selection of self-reactivity to positive selection of near-self-reactivity.
Autorzy:
Forsdyke DR; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
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Źródło:
Scandinavian journal of immunology [Scand J Immunol] 2019 Apr; Vol. 89 (4), pp. e12746. Date of Electronic Publication: 2019 Jan 24.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Clonal Selection, Antigen-Mediated*
Self Tolerance*
B-Lymphocytes/*physiology
T-Lymphocytes/*physiology
Animals ; Autoantigens/immunology ; Humans ; Lymphocyte Activation
Czasopismo naukowe
Tytuł:
Immune recognition of citrullinated epitopes.
Autorzy:
Nguyen H; Benaroya Research Institute at Virginia Mason, Seattle, WA, USA.
James EA; Benaroya Research Institute at Virginia Mason, Seattle, WA, USA.
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Źródło:
Immunology [Immunology] 2016 Oct; Vol. 149 (2), pp. 131-8. Date of Electronic Publication: 2016 Aug 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Autoantigens/*metabolism
Autoimmune Diseases/*immunology
Citrulline/*metabolism
Epitopes, T-Lymphocyte/*metabolism
T-Lymphocytes/*immunology
Animals ; Antigenic Variation ; Autoantigens/immunology ; Autoimmunity ; Epitopes, T-Lymphocyte/immunology ; HLA Antigens/metabolism ; Humans ; Immune Tolerance ; Lymphocyte Activation
Czasopismo naukowe
Tytuł:
Increased risk for T cell autoreactivity to ß-cell antigens in the mice expressing the A obesity-associated gene.
Autorzy:
Yong J; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA, 90095-1735, United States.; Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, CA, 92037, United States.
Tian J; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA, 90095-1735, United States.
Dang H; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA, 90095-1735, United States.
Wu TT; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA, 90095-1735, United States.
Atkinson MA; Departments of Pathology and Paediatrics, University of Florida Diabetes Institute, Gainesville, FL, 32610, United States.
Sun R; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA, 90095-1735, United States.
Kaufman DL; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA, 90095-1735, United States. .
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Źródło:
Scientific reports [Sci Rep] 2019 Mar 12; Vol. 9 (1), pp. 4269. Date of Electronic Publication: 2019 Mar 12.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Agouti Signaling Protein/*genetics
Diabetes Mellitus, Type 1/*immunology
Insulin-Secreting Cells/*immunology
Obesity/*immunology
T-Lymphocytes/*immunology
Animals ; Autoantigens/immunology ; Autoantigens/metabolism ; Autoimmunity/genetics ; Blood Glucose/analysis ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 1/diagnosis ; Diabetes Mellitus, Type 1/genetics ; Diet, High-Fat/adverse effects ; Disease Models, Animal ; Humans ; Insulin-Secreting Cells/metabolism ; Mice ; Mice, Transgenic ; Mutation ; Obesity/complications ; Obesity/genetics ; Obesity/pathology
Czasopismo naukowe
Tytuł:
Extrafollicular responses in humans and SLE.
Autorzy:
Jenks SA; Department of Medicine, Division of Rheumatology, Lowance Center for Human Immunology, Emory University, Atlanta, Georgia.; Lowance Center for Human Immunology, Emory University, Atlanta, Georgia.
Cashman KS; Department of Medicine, Division of Rheumatology, Lowance Center for Human Immunology, Emory University, Atlanta, Georgia.; Lowance Center for Human Immunology, Emory University, Atlanta, Georgia.
Woodruff MC; Department of Medicine, Division of Rheumatology, Lowance Center for Human Immunology, Emory University, Atlanta, Georgia.; Lowance Center for Human Immunology, Emory University, Atlanta, Georgia.
Lee FE; Lowance Center for Human Immunology, Emory University, Atlanta, Georgia.; Department of Medicine, Division of Pulmonary, Allergy and Critical Care, Emory University, Atlanta, Georgia.
Sanz I; Department of Medicine, Division of Rheumatology, Lowance Center for Human Immunology, Emory University, Atlanta, Georgia.; Lowance Center for Human Immunology, Emory University, Atlanta, Georgia.
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Źródło:
Immunological reviews [Immunol Rev] 2019 Mar; Vol. 288 (1), pp. 136-148.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms:
Autoantibodies/*metabolism
B-Lymphocyte Subsets/*immunology
B-Lymphocytes/*immunology
Lupus Erythematosus, Systemic/*immunology
T-Lymphocytes/*immunology
Animals ; Autoantigens/immunology ; Germinal Center/immunology ; Humans ; Lymphocyte Activation ; Mice ; Toll-Like Receptor 7/metabolism
Czasopismo naukowe
Tytuł:
FAS and RAS related Apoptosis defects: From autoimmunity to leukemia.
Autorzy:
Meynier S; Laboratory of Immunogenetics of Pediatric Autoimmune Diseases, INSERM UMR 1163, Paris, France.; Imagine Institute, Paris Descartes-Sorbonne Paris Cité University, Paris, France.
Rieux-Laucat F; Laboratory of Immunogenetics of Pediatric Autoimmune Diseases, INSERM UMR 1163, Paris, France.; Imagine Institute, Paris Descartes-Sorbonne Paris Cité University, Paris, France.
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Źródło:
Immunological reviews [Immunol Rev] 2019 Jan; Vol. 287 (1), pp. 50-61.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Apoptosis/*genetics
Autoimmunity/*genetics
B-Lymphocytes/*immunology
Leukemia/*genetics
T-Lymphocytes/*immunology
fas Receptor/*genetics
ras Proteins/*genetics
Animals ; Autoantigens/immunology ; Humans ; Mutation/genetics ; Receptors, Antigen/genetics
Czasopismo naukowe
Tytuł:
The potential role for infections in the pathogenesis of autoimmune Addison's disease.
Autorzy:
Hellesen A; Department of Clinical Science, University of Bergen, Bergen, Norway.; K.G. Jebsen Senter for Autoimmune Sykdommer, University of Bergen, Bergen, Norway.
Bratland E; Department of Clinical Science, University of Bergen, Bergen, Norway.; K.G. Jebsen Senter for Autoimmune Sykdommer, University of Bergen, Bergen, Norway.
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Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2019 Jan; Vol. 195 (1), pp. 52-63. Date of Electronic Publication: 2018 Sep 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Addison Disease/*etiology
T-Lymphocytes/*immunology
Virus Diseases/*complications
Animals ; Autoantibodies/metabolism ; Autoantigens/immunology ; Autoimmunity ; Gene-Environment Interaction ; Humans ; Steroid 21-Hydroxylase/immunology
Czasopismo naukowe

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