Temat: "beta-Naphthoflavone" - OpacWWW - Prolib Integro

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Tytuł:: β-Naphtoflavone and Ethanol Induce Cytochrome P450 and Protect towards MPP⁺ Toxicity in Human Neuroblastoma SH-SY5Y Cells.
Autorzy:: Fernandez-Abascal J; Dipartimento di Scienze della Vita, Università di Siena, Via Aldo Moro 2, 53100 Siena, Italy. .
Ripullone M; Dipartimento di Scienze della Vita, Università di Siena, Via Aldo Moro 2, 53100 Siena, Italy. .
Valeri A; Molecular Horizon srl, Via Montelino 32, Bettona, 06084 Perugia, Italy. .
Leone C; Dipartimento di Scienze della Vita, Università di Siena, Via Aldo Moro 2, 53100 Siena, Italy. .
Valoti M; Dipartimento di Scienze della Vita, Università di Siena, Via Aldo Moro 2, 53100 Siena, Italy. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2018 Oct 28; Vol. 19 (11). Date of Electronic Publication: 2018 Oct 28.
Typ publikacji:: Journal Article
MeSH Terms:: Cytochrome P-450 Enzyme System/*metabolism
Ethanol/*pharmacology
Neuroprotective Agents/*pharmacology
beta-Naphthoflavone/*pharmacology
1-Methyl-4-phenylpyridinium/toxicity ; Cell Line, Tumor ; Cell Survival/drug effects ; Cytochrome P-450 Enzyme System/genetics ; Humans

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Skocz do pozycji: 2.

Tytuł:: Precision-cut liver slices from rats of different ages: basal cytochrome P450-dependent monooxygenase activities and inducibility.
Autorzy:: Lupp A; Institute of Pharmacology and Toxicology, Friedrich Schiller University Jena, Nonnenplan 4, 07743, Jena, Germany. />Glöckner R
Etzrodt J
Müller D; Pokaż więcej
Źródło:: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2008 Nov; Vol. 392 (6), pp. 1173-84. Date of Electronic Publication: 2008 Jul 16.
Typ publikacji:: Journal Article
MeSH Terms:: Aging*/metabolism
Aging*/pathology
Mixed Function Oxygenases*/analysis
Mixed Function Oxygenases*/metabolism
Testosterone*/analysis
Testosterone*/metabolism
Cytochrome P-450 Enzyme System/*metabolism
Liver/*enzymology
Organ Culture Techniques/*methods
Animals ; Anti-Inflammatory Agents/pharmacology ; Coumarins/pharmacology ; Cytochrome P-450 CYP1A1/analysis ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 Enzyme System/analysis ; Dexamethasone/pharmacology ; Dimethyl Sulfoxide/pharmacology ; Enzyme Induction/drug effects ; Enzyme Induction/physiology ; Enzyme Inhibitors/pharmacology ; Hydroxylation ; Liver/pathology ; Male ; Oxazines/pharmacology ; Phenobarbital/pharmacology ; Pregnenolone Carbonitrile/pharmacology ; Rats ; Rats, Wistar ; Time Factors ; beta-Naphthoflavone/pharmacology

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Skocz do pozycji: 3.

Tytuł:: Determination of CYP activity in precision-cut liver slices: whether to use intact slices or slice homogenate.
Autorzy:: Glöckner R; Institute of Pharmacology and Toxicology, Friedrich Schiller University, 07740, Jena, Germany. />Lieder A
Lupp A; Pokaż więcej
Źródło:: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2008 Nov; Vol. 392 (6), pp. 1167-72. Date of Electronic Publication: 2008 Jul 10.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Cytochrome P-450 Enzyme System*/analysis
Cytochrome P-450 Enzyme System*/metabolism
Liver*/enzymology
Liver*/pathology
Testosterone*/analysis
Testosterone*/metabolism
Antineoplastic Agents/*pharmacology
Enzyme Inhibitors/*pharmacology
Organ Culture Techniques/*methods
Animals ; Coumarins/pharmacology ; Dexamethasone/pharmacology ; Enzyme Induction/drug effects ; Enzyme Induction/physiology ; Female ; Hydroxylation ; Kinetics ; Male ; Rats ; Rats, Wistar ; Sex Factors ; beta-Naphthoflavone/pharmacology

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Skocz do pozycji: 4.

Tytuł:: Temporal evaluation of CYP mRNA in mice administered with prototypical P450 inducers: comparison with conventional protein/enzyme methods.
Autorzy:: Wang EJ; Department of Genetic and Molecular Toxicology, Schering-Plough Corporation, Summit, New Jersey 07901, USA. />Mandakas G
Palamanda J
Lin X
Kumari P
Chu I
Soares A
Smith RJ
Snyder RD
Gu YZ; Pokaż więcej
Źródło:: Drug and chemical toxicology [Drug Chem Toxicol] 2008; Vol. 31 (4), pp. 501-13.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Reverse Transcriptase Polymerase Chain Reaction*
Cytochrome P-450 Enzyme System/*biosynthesis
Drug Evaluation, Preclinical/*methods
Liver/*drug effects
RNA, Messenger/*biosynthesis
Animals ; Clofibrate/pharmacology ; Cytochrome P-450 Enzyme System/genetics ; Dexamethasone/pharmacology ; Enzyme Induction/drug effects ; Feasibility Studies ; Isoenzymes ; Liver/enzymology ; Male ; Mice ; Phenobarbital/pharmacology ; Reproducibility of Results ; Time Factors ; beta-Naphthoflavone/pharmacology

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Skocz do pozycji: 5.

Tytuł:: Upregulation of cytochromes P450 2B in rat liver by orphenadrine.
Autorzy:: Murray M; Department of Physiology and Pharmacology, School of Medical Sciences, University of New South Wales, Sydney, NSW 2052, Australia. />Fiala-Beer E
Sutton D; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2003 Jun; Vol. 139 (4), pp. 787-96.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cytochrome P-450 Enzyme System/*drug effects
Cytochrome P-450 Enzyme System/*genetics
Microsomes, Liver/*enzymology
Orphenadrine/*pharmacokinetics
Up-Regulation/*drug effects
Animals ; Cytochrome P-450 Enzyme Inhibitors ; Dexamethasone/administration & dosage ; Dexamethasone/pharmacokinetics ; Dimethyl Sulfoxide/administration & dosage ; Dimethyl Sulfoxide/pharmacokinetics ; Enzyme Induction/drug effects ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/physiology ; Injections, Intraperitoneal ; Male ; Orphenadrine/administration & dosage ; Orphenadrine/metabolism ; Phenobarbital/administration & dosage ; Phenobarbital/metabolism ; Phenobarbital/pharmacokinetics ; Protein Biosynthesis/drug effects ; Protein Biosynthesis/physiology ; Rats ; Rats, Wistar ; Up-Regulation/physiology ; beta-Naphthoflavone/administration & dosage ; beta-Naphthoflavone/metabolism ; beta-Naphthoflavone/pharmacokinetics

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Skocz do pozycji: 6.

Tytuł:: Selectivity of 7-alkoxycoumarins as probe substrates for rat hepatic cytochrome P450 forms is influenced by the substitution pattern on the coumarin nucleus.
Autorzy:: Fry JR; School of Biomedical Sciences, Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UK. />Hammond AH
Jassi KL
Bass AE
Bruce G
Laughton C
Shaw PN
Bylov IE
Kovalenko SM; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2004 Aug; Vol. 34 (8), pp. 707-22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Coumarins/*metabolism
Cytochrome P-450 Enzyme System/*metabolism
Microsomes, Liver/*enzymology
7-Alkoxycoumarin O-Dealkylase/metabolism ; Adolescent ; Adult ; Aged ; Animals ; Coumarins/chemistry ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 CYP1A2/metabolism ; Cytochrome P-450 CYP2B1/antagonists & inhibitors ; Cytochrome P-450 CYP2B1/metabolism ; Enzyme Induction/drug effects ; Enzyme Inhibitors/pharmacology ; Female ; Humans ; In Vitro Techniques ; Isoenzymes/metabolism ; Male ; Microsomes, Liver/drug effects ; Middle Aged ; Molecular Probes ; Molecular Structure ; Phenobarbital/pharmacology ; Rats ; Rats, Wistar ; Selegiline/pharmacology ; Substrate Specificity ; beta-Naphthoflavone/pharmacology

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Skocz do pozycji: 7.

Tytuł:: Endothelial cell cytochrome P450 1A1 and 1B1: up-regulation by shear stress.
Autorzy:: Eskin SG; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30309, USA. />Turner NA
McIntire LV; Pokaż więcej
Źródło:: Endothelium : journal of endothelial cell research [Endothelium] 2004 Jan-Feb; Vol. 11 (1), pp. 1-10.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Cytochrome P-450 CYP1A1/*genetics
Cytochrome P-450 Enzyme System/*genetics
Endothelial Cells/*metabolism
Regional Blood Flow/*physiology
Up-Regulation/*physiology
Aryl Hydrocarbon Hydroxylases ; Cells, Cultured ; Connective Tissue Growth Factor ; Culture Media, Conditioned/pharmacology ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 CYP1B1 ; Cytochrome P-450 Enzyme System/metabolism ; Endothelial Cells/drug effects ; Endothelin-1/genetics ; Enzyme Inhibitors/pharmacology ; Humans ; Immediate-Early Proteins/genetics ; Infant, Newborn ; Intercellular Signaling Peptides and Proteins/genetics ; RNA, Messenger/drug effects ; RNA, Messenger/metabolism ; Stress, Mechanical ; Up-Regulation/drug effects ; beta-Naphthoflavone/pharmacology

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Skocz do pozycji: 8.

Tytuł:: Use of cultured precision-cut rat lung slices to study the in vitro induction of pulmonary cytochrome P450 forms.
Autorzy:: Lake BG; BIBRA International Ltda. UK. />Meredith C
Scott MP
Renwick AB
Price RJ; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2003 Jul; Vol. 33 (7), pp. 691-702.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Culture Techniques/*methods
Cytochrome P-450 Enzyme System/*drug effects
Cytochrome P-450 Enzyme System/*metabolism
Lung/*drug effects
Lung/*enzymology
Tissue Fixation/*methods
Animals ; Aroclors/pharmacology ; Benzo(a)pyrene/pharmacology ; Culture Techniques/instrumentation ; Cytochrome P-450 CYP1A1/drug effects ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 CYP2B1/drug effects ; Cytochrome P-450 CYP2B1/metabolism ; Dose-Response Relationship, Drug ; Male ; Rats ; beta-Naphthoflavone/pharmacology

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Skocz do pozycji: 9.

Tytuł:: Studies on the induction of rat hepatic CYP1A, CYP2B, CYP3A and CYP4A subfamily form mRNAs in vivo and in vitro using precision-cut rat liver slices.
Autorzy:: Meredith C; BIBRA International Ltd, Carshalton SM5 4DS, UK.
Scott MP
Renwick AB
Price RJ
Lake BG; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2003 May; Vol. 33 (5), pp. 511-27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cytochrome P-450 Enzyme System/*metabolism
Liver/*enzymology
RNA, Messenger/*biosynthesis
Animals ; Chlorodiphenyl (54% Chlorine)/pharmacology ; Clofenapate/pharmacology ; Culture Techniques ; Cytochrome P-450 Enzyme Inhibitors ; Cytochrome P-450 Enzyme System/genetics ; DNA Primers/genetics ; Dexamethasone/pharmacology ; Enzyme Induction/drug effects ; Isoenzymes/antagonists & inhibitors ; Isoenzymes/genetics ; Isoenzymes/metabolism ; Male ; Oligonucleotide Probes/genetics ; Organ Size ; Phenobarbital/pharmacology ; Pregnenolone Carbonitrile/pharmacology ; RNA, Messenger/analysis ; RNA, Messenger/genetics ; Rats ; Rats, Sprague-Dawley ; beta-Naphthoflavone/pharmacology

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Skocz do pozycji: 10.

Tytuł:: CYP isoform induction screening in 96-well plates: use of 7-benzyloxy-4-trifluoromethylcoumarin as a substrate for studies with rat hepatocytes.
Autorzy:: Price RJ; TNO BIBRA International Ltd, Carshalton, UK.
Surry D
Renwick AB
Meneses-Lorente G
Lake BG
Evans DC; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2000 Aug; Vol. 30 (8), pp. 781-95.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Coumarins/*metabolism
Cytochrome P-450 Enzyme System/*biosynthesis
Liver/*enzymology
Animals ; Clofenapate/pharmacology ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 CYP1A2/metabolism ; Cytochrome P-450 CYP2B1/metabolism ; Dexamethasone/pharmacology ; Enzyme Induction/drug effects ; Glucocorticoids/pharmacology ; Glucuronic Acid/metabolism ; Isoenzymes/biosynthesis ; Isoniazid/pharmacology ; Kinetics ; Liver/drug effects ; Male ; Phenobarbital/pharmacology ; Rats ; Rats, Sprague-Dawley ; Recombinant Proteins/metabolism ; Substrate Specificity ; Sulfates/metabolism ; beta-Naphthoflavone/pharmacology

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Skocz do pozycji: 11.

Tytuł:: Expression and induction of CYP1A1/1A2, CYP2A6 and CYP3A4 in primary cultures of human hepatocytes: a 10-year follow-up.
Autorzy:: Meunier V; Sanofi Recherche, Department of Preclinical Metabolism and Pharmacokinetics, Montpellier, France.
Bourrié M
Julian B
Marti E
Guillou F
Berger Y
Fabre G; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2000 Jun; Vol. 30 (6), pp. 589-607.
Typ publikacji:: Journal Article
MeSH Terms:: Cytochrome P-450 Enzyme System/*biosynthesis
Hepatocytes/*enzymology
Liver/*enzymology
Adult ; Aged ; Biotransformation/drug effects ; Blotting, Western ; Cells, Cultured ; Cytochrome P-450 CYP3A ; Cytochrome P-450 Enzyme System/drug effects ; Cytochrome P-450 Enzyme System/metabolism ; Dexamethasone/pharmacology ; Enzyme Induction/drug effects ; Female ; Hepatocytes/cytology ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Humans ; Isoenzymes/biosynthesis ; Isoenzymes/drug effects ; Isoenzymes/metabolism ; Kinetics ; Liver/cytology ; Liver/drug effects ; Liver/metabolism ; Male ; Microsomes, Liver/drug effects ; Microsomes, Liver/enzymology ; Microsomes, Liver/metabolism ; Middle Aged ; Phenacetin/pharmacology ; Phenobarbital/pharmacology ; Time Factors ; beta-Naphthoflavone/pharmacology

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Skocz do pozycji: 12.

Tytuł:: Association of cytochrome P450 induction with oxidative stress in vivo as evidenced by 3-hydroxylation of salicylate.
Autorzy:: Strolin-Benedetti M; Zambon Group SpA, Bresso, Milan, Italy.
Brogin G
Bani M
Oesch F
Hengstler JG; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 1999 Nov; Vol. 29 (11), pp. 1171-80.
Typ publikacji:: Journal Article
MeSH Terms:: Aryl Hydrocarbon Hydroxylases*
Gentisates*
Cytochrome P-450 Enzyme System/*biosynthesis
Oxidative Stress/*physiology
Salicylates/*metabolism
Animals ; Cytochrome P-450 CYP1A1/biosynthesis ; Cytochrome P-450 CYP1A2/biosynthesis ; Cytochrome P-450 CYP3A ; Dexamethasone/pharmacology ; Enzyme Induction/drug effects ; Enzyme Inhibitors/analysis ; Enzyme Inhibitors/metabolism ; Hydroxybenzoates/analysis ; Hydroxybenzoates/metabolism ; Hydroxylation ; Male ; Oxidoreductases, N-Demethylating/biosynthesis ; Phenobarbital/pharmacology ; Proadifen/analysis ; Proadifen/metabolism ; Rats ; Rats, Sprague-Dawley ; beta-Naphthoflavone/pharmacology

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Skocz do pozycji: 13.

Tytuł:: High throughput ribonuclease protection assay for the determination of CYP3A mRNA induction in cultured rat hepatocytes.
Autorzy:: Surry DD; Department of Drug Metabolism and Pharmacokinetics, Neuroscience Research Centre, Merck Research Laboratories, Harlow, UK. Dominic_ />McAllister G
Meneses-Lorente G
Evans DC; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 1999 Aug; Vol. 29 (8), pp. 827-38.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Aryl Hydrocarbon Hydroxylases*
Cytochrome P-450 Enzyme System/*genetics
In Situ Hybridization/*methods
Liver/*cytology
Liver/*enzymology
Oxidoreductases, N-Demethylating/*genetics
RNA, Messenger/*analysis
Animals ; Cells, Cultured ; Clofenapate/pharmacology ; Cloning, Molecular ; Cytochrome P-450 CYP3A ; Cytochrome P-450 CYP4A ; Cytochrome P-450 Enzyme System/drug effects ; Dexamethasone/pharmacology ; Enzyme Activation/drug effects ; Enzyme Inhibitors/pharmacology ; Female ; Mixed Function Oxygenases/drug effects ; Mixed Function Oxygenases/genetics ; Oxidoreductases, N-Demethylating/drug effects ; Pregnenolone Carbonitrile/pharmacology ; RNA Probes ; Rats ; Rats, Sprague-Dawley ; Ribonucleases/metabolism ; Tetrazolium Salts/chemistry ; Toxicity Tests/methods ; beta-Naphthoflavone/pharmacology

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Skocz do pozycji: 14.

Tytuł:: A comparison of basal and induced hepatic microsomal cytochrome P450 monooxygenase activities in the cynomolgus monkey (Macaca fascicularis) and man.
Autorzy:: Weaver RJ; Servier Research & Development, Fulmer, Slough, UK.
Dickins M
Burke MD; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 1999 May; Vol. 29 (5), pp. 467-82.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cytochrome P-450 Enzyme System/*metabolism
Microsomes, Liver/*enzymology
Steroid Hydroxylases/*metabolism
Adult ; Animals ; Cytochrome P-450 Enzyme System/drug effects ; Enzyme Inhibitors/pharmacology ; Female ; Humans ; Immunoblotting ; Macaca fascicularis ; Male ; Microsomes, Liver/drug effects ; Middle Aged ; Phenobarbital/pharmacology ; Rifampin/pharmacology ; Steroid Hydroxylases/drug effects ; beta-Naphthoflavone/pharmacology

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Skocz do pozycji: 15.

Tytuł:: A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.
Autorzy:: Ogg MS; Molecular Toxicology Group, School of Biological Sciences, University of Surrey, Guildford, UK.
Williams JM
Tarbit M
Goldfarb PS
Gray TJ
Gibson GG; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 1999 Mar; Vol. 29 (3), pp. 269-79.
Typ publikacji:: Journal Article
MeSH Terms:: Cytochrome P-450 Enzyme System/*drug effects
Cytochrome P-450 Enzyme System/*genetics
Drug Evaluation, Preclinical/*methods
Mixed Function Oxygenases/*drug effects
Mixed Function Oxygenases/*genetics
Xenobiotics/*pharmacology
Alkaline Phosphatase/genetics ; Caffeine/pharmacology ; Carbamazepine/pharmacology ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/genetics ; Clofibrate/pharmacology ; Cytochrome P-450 CYP3A ; Dexamethasone/pharmacology ; Dose-Response Relationship, Drug ; Gene Expression Regulation/drug effects ; Genes, Reporter ; Glucocorticoids/pharmacology ; Hormone Antagonists/pharmacology ; Humans ; Isoniazid/pharmacology ; Mifepristone/pharmacology ; Phenobarbital/pharmacology ; Phenylbutazone/pharmacology ; Phenytoin/pharmacology ; Receptors, Glucocorticoid/drug effects ; Receptors, Glucocorticoid/genetics ; Recombinant Proteins/drug effects ; Recombinant Proteins/genetics ; Rifampin/pharmacology ; Tumor Cells, Cultured/drug effects ; beta-Naphthoflavone/pharmacology

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Skocz do pozycji: 16.

Tytuł:: Beta-naphthoflavone induced CYP1A1 and 1A3 proteins in the liver of rainbow trout (Oncorhynchus mykiss).
Autorzy:: Gooneratne R; Department of Agricultural Chemistry, Oregon State University, Corvallis 97331, USA.
Miranda CL
Henderson MC
Buhler DR; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 1997 Feb; Vol. 27 (2), pp. 175-87.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Aryl Hydrocarbon Hydroxylases*
Cytochrome P-450 CYP1A1/*chemistry
Cytochrome P-450 Enzyme System/*biosynthesis
Cytochrome P-450 Enzyme System/*chemistry
beta-Naphthoflavone/*pharmacology
Amino Acid Sequence ; Animals ; Cytochrome P-450 CYP1A1/isolation & purification ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 Enzyme System/isolation & purification ; Cytochrome P-450 Enzyme System/metabolism ; Electrophoresis, Polyacrylamide Gel ; Enzyme Induction ; Microsomes, Liver/enzymology ; Molecular Sequence Data ; Oncorhynchus mykiss

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Skocz do pozycji: 17.

Tytuł:: Lead nitrate inhibits the induction of CYP1A mRNAs by aromatic amines but not by aryl hydrocarbons in the rat liver.
Autorzy:: Degawa M; Faculty of Pharmaceutical Sciences, Tohoku University, Sendai.
Matsuda K
Arai H
Hashimoto Y; Pokaż więcej
Źródło:: Journal of biochemistry [J Biochem] 1996 Sep; Vol. 120 (3), pp. 547-51.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carcinogens/*pharmacology
Cytochrome P-450 CYP1A2/*biosynthesis
Cytochrome P-450 Enzyme System/*biosynthesis
Microsomes, Liver/*enzymology
Animals ; Base Sequence ; Benzo(a)pyrene/pharmacology ; Carbolines/pharmacology ; Enzyme Induction/drug effects ; Imidazoles/pharmacology ; Male ; Methylcholanthrene/pharmacology ; Microsomes, Liver/drug effects ; Oligonucleotide Probes ; Rats ; Rats, Inbred F344 ; Structure-Activity Relationship ; beta-Naphthoflavone/pharmacology ; p-Aminoazobenzene/analogs & derivatives ; p-Aminoazobenzene/pharmacology

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Skocz do pozycji: 18.

Tytuł:: Induction of CYP1A1 gene by benzimidazole derivatives during Caco-2 cell differentiation. Evidence for an aryl-hydrocarbon receptor-mediated mechanism.
Autorzy:: Daujat M; Unité 128 INSERM, CNRS, Montpellier, France.
Charrasse S
Fabre I
Lesca P
Jounaïdi Y
Larroque C
Poellinger L
Maurel P; Pokaż więcej
Źródło:: European journal of biochemistry [Eur J Biochem] 1996 May 01; Vol. 237 (3), pp. 642-52.
Typ publikacji:: Journal Article
MeSH Terms:: Benzimidazoles/*pharmacology
Cytochrome P-450 Enzyme System/*genetics
Receptors, Aryl Hydrocarbon/*drug effects
Receptors, Aryl Hydrocarbon/*metabolism
2-Pyridinylmethylsulfinylbenzimidazoles ; Anti-Ulcer Agents/pharmacology ; Base Sequence ; Benzoflavones/pharmacology ; Binding Sites ; Caco-2 Cells ; Cell Differentiation ; Cimetidine/pharmacology ; Gene Expression Regulation/drug effects ; Humans ; Kinetics ; Lansoprazole ; Molecular Sequence Data ; Oligonucleotide Probes/genetics ; Omeprazole/analogs & derivatives ; Omeprazole/pharmacology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; beta-Naphthoflavone

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Skocz do pozycji: 19.

Tytuł:: Induction, regulation and messenger half-life of cytochromes P450 IA1, IA2 and IIIA6 in primary cultures of rabbit hepatocytes. CYP 1A1, 1A2 and 3A6 chromosome location in the rabbit and evidence that post-transcriptional control of gene IA2 does not involve mRNA stabilization.
Autorzy:: Daujat M; INSERM U-128, CNRS, Montpellier, France.
Clair P
Astier C
Fabre I
Pineau T
Yerle M
Gellin J
Maurel P; Pokaż więcej
Źródło:: European journal of biochemistry [Eur J Biochem] 1991 Sep 01; Vol. 200 (2), pp. 501-10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: RNA Processing, Post-Transcriptional*
Cytochrome P-450 Enzyme System/*metabolism
Liver/*enzymology
RNA, Messenger/*metabolism
Animals ; Benzoflavones/pharmacology ; Blotting, Northern ; Cells, Cultured ; Chromosome Mapping ; Cycloheximide/pharmacology ; Cytochrome P-450 CYP1A2 ; Cytochrome P-450 Enzyme System/biosynthesis ; Cytochrome P-450 Enzyme System/genetics ; DNA/genetics ; Dactinomycin/pharmacology ; Dexamethasone/pharmacology ; Gene Expression/drug effects ; Half-Life ; Oxidoreductases/biosynthesis ; Oxidoreductases/genetics ; Oxidoreductases/metabolism ; Plasmids ; Rabbits ; Rifampin/pharmacology ; beta-Naphthoflavone

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Skocz do pozycji: 20.

Tytuł:: Hydroxylations in biosynthesis of bile acids. Cytochrome P-450 LM4 and 12alpha-hydroxylation of 5beta-cholestane-3alpha, 7alpha-diol.
Autorzy:: Hansson R
Wikvall K; Pokaż więcej
Źródło:: European journal of biochemistry [Eur J Biochem] 1982 Jul; Vol. 125 (2), pp. 423-9.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Benzoflavones/*metabolism
Bile Acids and Salts/*biosynthesis
Cytochrome P-450 Enzyme System/*metabolism
Flavonoids/*metabolism
Microsomes, Liver/*enzymology
NADPH-Ferrihemoprotein Reductase/*metabolism
Animals ; Benzoflavones/pharmacology ; Catalysis ; Hydroxylation ; Phenobarbital/pharmacology ; Rabbits ; Starvation/metabolism ; beta-Naphthoflavone

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Wyświetlanie 1-20 z 23

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