Temat: "beta-arrestin" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Role of Formyl Peptide Receptors and β-Arrestin-1 in suPAR Signal Transduction in Mouse Podocytes: Interactions with αVβ3-Integrin.
Autorzy:: Kim EY; Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.
Dryer SE; Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.; Department of Biomedical Sciences, Tilman J. Fertitta Family College of Medicine, University of Houston, Houston, TX 77204, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Jan 17; Vol. 13 (2). Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: beta-Arrestin 1*
Receptors, Formyl Peptide*
Receptors, Urokinase Plasminogen Activator*
Animals ; Mice ; Integrin beta3 ; Podocytes ; Reactive Oxygen Species ; Receptor for Advanced Glycation End Products ; Signal Transduction ; Integrin alpha5

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Skocz do pozycji: 2.

Tytuł:: Platelet P2Y 1 receptor exhibits constitutive G protein signaling and β-arrestin 2 recruitment.
Autorzy:: Ribes A; Laboratoire d'Hématologie, Centre Hospitalier Universitaire de Toulouse, F-31000, Toulouse, France.; INSERM, UMR 1297, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, F-31432, Toulouse, France.
Garcia C; Laboratoire d'Hématologie, Centre Hospitalier Universitaire de Toulouse, F-31000, Toulouse, France.; INSERM, UMR 1297, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, F-31432, Toulouse, France.
Gratacap MP; INSERM, UMR 1297, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, F-31432, Toulouse, France.
Kostenis E; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Nussallee 6, 53115, Bonn, Germany.
Martinez LO; INSERM, UMR 1297, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, F-31432, Toulouse, France.
Payrastre B; Laboratoire d'Hématologie, Centre Hospitalier Universitaire de Toulouse, F-31000, Toulouse, France.; INSERM, UMR 1297, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, F-31432, Toulouse, France.
Sénard JM; INSERM, UMR 1297, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, F-31432, Toulouse, France.; Service de Pharmacologie Clinique, Centre Hospitalier Universitaire de Toulouse, Faculté de Médecine, Université de Toulouse, F-31000, Toulouse, France.
Galés C; INSERM, UMR 1297, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, F-31432, Toulouse, France. .
Pons V; INSERM, UMR 1297, Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, F-31432, Toulouse, France. .; Pokaż więcej
Źródło:: BMC biology [BMC Biol] 2023 Feb 01; Vol. 21 (1), pp. 14. Date of Electronic Publication: 2023 Feb 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: beta-Arrestin 2*/metabolism
Drug Inverse Agonism*
GTP-Binding Proteins*/metabolism
Signal Transduction*
Receptors, Purinergic P2Y1*/metabolism
Animals ; Humans ; Mice ; HEK293 Cells ; Blood Platelets

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Skocz do pozycji: 3.

Tytuł:: The Opioid Receptor Influences Circadian Rhythms in Human Keratinocytes through the β-Arrestin Pathway.
Autorzy:: Bigliardi P; Department of Dermatology, University of Minnesota, Minneapolis, MN 55455, USA.; Stem Cell Institue, McGuire Translational Research Facility, University of Minnesota, Minneapolis, MN 55455, USA.
Junnarkar S; Agency for Science, Technology and Research, Singapore 138632, Singapore.
Markale C; Department of Dermatology, University of Minnesota, Minneapolis, MN 55455, USA.; Stem Cell Institue, McGuire Translational Research Facility, University of Minnesota, Minneapolis, MN 55455, USA.
Lo S; Department of Dermatology, University of Minnesota, Minneapolis, MN 55455, USA.; Stem Cell Institue, McGuire Translational Research Facility, University of Minnesota, Minneapolis, MN 55455, USA.
Bigliardi E; Department of Dermatology, University of Minnesota, Minneapolis, MN 55455, USA.; Stem Cell Institue, McGuire Translational Research Facility, University of Minnesota, Minneapolis, MN 55455, USA.
Kalyuzhny A; Department of Neuroscience, Medical School, University of Minnesota, Minneapolis, MN 55455, USA.
Ong S; Agency for Science, Technology and Research, Singapore 138632, Singapore.
Dunn R; Agency for Science, Technology and Research, Singapore 138632, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 639798, Singapore.
Wahli W; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 639798, Singapore.; Unité Mixte de Recherche (UMR) 1331, Institut National de la Recherche Agronomique (INRA), ToxAlim, 31000 Toulouse, France.; Center for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland.
Bigliardi-Qi M; Department of Dermatology, University of Minnesota, Minneapolis, MN 55455, USA.; Stem Cell Institue, McGuire Translational Research Facility, University of Minnesota, Minneapolis, MN 55455, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Jan 25; Vol. 13 (3). Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:: Journal Article
MeSH Terms:: Receptors, Opioid*/genetics
Neoplasms*
Humans ; beta-Arrestins ; Keratinocytes ; Circadian Rhythm/physiology ; beta-Arrestin 1 ; Enkephalin, Methionine

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Skocz do pozycji: 4.

Tytuł:: In vivo identification of Drosophila rhodopsin interaction partners by biotin proximity labeling.
Autorzy:: Feizy N; Department of Biochemistry, Institute of Biology, University of Hohenheim, Stuttgart, Germany.
Leuchtenberg SF; Department of Biochemistry, Institute of Biology, University of Hohenheim, Stuttgart, Germany.
Steiner C; Department of Biochemistry, Institute of Biology, University of Hohenheim, Stuttgart, Germany.
Würtz B; Mass Spectrometry Unit, Core Facility Hohenheim, University of Hohenheim, Stuttgart, Germany.
Fliegner L; Department of Biochemistry, Institute of Biology, University of Hohenheim, Stuttgart, Germany.
Huber A; Department of Biochemistry, Institute of Biology, University of Hohenheim, Stuttgart, Germany. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Jan 23; Vol. 14 (1), pp. 1986. Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:: Journal Article
MeSH Terms:: Rhodopsin*
Biotin*
Animals ; Drosophila ; beta-Arrestin 1 ; Membrane Proteins

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Skocz do pozycji: 5.

Tytuł:: Single-Molecule Imaging Reveals Differential AT1R Stoichiometry Change in Biased Signaling.
Autorzy:: Qin G; Key Laboratory of Molecular Nanostructure and Nanotechnology, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Xu J; Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Liang Y; Key Laboratory of Molecular Nanostructure and Nanotechnology, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Fang X; Key Laboratory of Molecular Nanostructure and Nanotechnology, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou 310022, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 27; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 27.
Typ publikacji:: Journal Article
MeSH Terms:: Receptor, Angiotensin, Type 1*
Single Molecule Imaging*
Ligands ; Signal Transduction ; beta-Arrestin 1 ; GTP-Binding Proteins

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Skocz do pozycji: 6.

Tytuł:: Delineating the interactions between the cannabinoid CB 2 receptor and its regulatory effectors; β-arrestins and GPCR kinases.
Autorzy:: Patel M; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Matti C; Department of Biology, Biotechnology Institute Thurgau (BITg) at the University of Konstanz, Kreuzlingen, Switzerland.
Grimsey NL; Department of Pharmacology and Clinical Pharmacology, School of Medical Sciences, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
Legler DF; Department of Biology, Biotechnology Institute Thurgau (BITg) at the University of Konstanz, Kreuzlingen, Switzerland.; Faculty of Biology, University of Konstanz, Konstanz, Germany.; Theodor Kocher Institute, University of Bern, Bern, Switzerland.
Javitch JA; Department of Psychiatry and Pharmacology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, New York, USA.
Finlay DB; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Glass M; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 May; Vol. 179 (10), pp. 2223-2239. Date of Electronic Publication: 2022 Feb 07.
Typ publikacji:: Journal Article
MeSH Terms:: Cannabinoids*
G-Protein-Coupled Receptor Kinases*/metabolism
Receptor, Cannabinoid, CB2*/metabolism
beta-Arrestin 2*/genetics
beta-Arrestin 2*/metabolism
HEK293 Cells ; Humans ; Phosphorylation ; beta-Arrestins/metabolism

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Skocz do pozycji: 7.

Tytuł:: LSD-stimulated behaviors in mice require β-arrestin 2 but not β-arrestin 1.
Autorzy:: Rodriguiz RM; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, 354 Sands Building, 303 Research Drive, PO Box 103203, Durham, NC, 27710, USA.; Mouse Behavioral and Neuroendocrine Analysis Core Facility, Duke University Medical Center, Durham, NC, 27710, USA.
Nadkarni V; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, 354 Sands Building, 303 Research Drive, PO Box 103203, Durham, NC, 27710, USA.
Means CR; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, 354 Sands Building, 303 Research Drive, PO Box 103203, Durham, NC, 27710, USA.; Mouse Behavioral and Neuroendocrine Analysis Core Facility, Duke University Medical Center, Durham, NC, 27710, USA.
Pogorelov VM; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, 354 Sands Building, 303 Research Drive, PO Box 103203, Durham, NC, 27710, USA.
Chiu YT; Division of Chemical Biology and Medicinal Chemistry, Department of Pharmacology, Center for Integrative Chemical Biology and Drug Discovery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, 27599, USA.
Roth BL; Division of Chemical Biology and Medicinal Chemistry, Department of Pharmacology, Center for Integrative Chemical Biology and Drug Discovery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, 27599, USA.; Division of Chemical Biology and Medicinal Chemistry, Department of Pharmacology and National Institute of Mental Health Psychoactive Drug Screening Program, Center for Integrative Chemical Biology and Drug Discovery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, 27599, USA.
Wetsel WC; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, 354 Sands Building, 303 Research Drive, PO Box 103203, Durham, NC, 27710, USA. .; Mouse Behavioral and Neuroendocrine Analysis Core Facility, Duke University Medical Center, Durham, NC, 27710, USA. .; Departments of Cell Biology and Neurobiology, Duke University Medical Center, Durham, NC, 27710, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Sep 03; Vol. 11 (1), pp. 17690. Date of Electronic Publication: 2021 Sep 03.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Behavior, Animal/*drug effects
Lysergic Acid Diethylamide/*pharmacology
Serotonin Receptor Agonists/*pharmacology
beta-Arrestin 1/*metabolism
beta-Arrestin 2/*metabolism
Animals ; Grooming/drug effects ; Mice ; Mice, Knockout ; Motor Activity/drug effects ; Signal Transduction/drug effects ; beta-Arrestin 1/genetics ; beta-Arrestin 2/genetics

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Skocz do pozycji: 8.

Tytuł:: Differential Involvement of ACKR3 C-Tail in β-Arrestin Recruitment, Trafficking and Internalization.
Autorzy:: Zarca A; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
Perez C; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
van den Bor J; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
Bebelman JP; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
Heuninck J; Institut de Génomique Fonctionnelle (IGF), Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France.
de Jonker RJF; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
Durroux T; Institut de Génomique Fonctionnelle (IGF), Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France.
Vischer HF; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
Siderius M; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
Smit MJ; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Mar 11; Vol. 10 (3). Date of Electronic Publication: 2021 Mar 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Endocytosis*
Receptors, CXCR/*metabolism
beta-Arrestin 1/*metabolism
beta-Arrestin 2/*metabolism
Biosensing Techniques ; Chemokine CXCL12/pharmacology ; Fluorescence Resonance Energy Transfer ; G-Protein-Coupled Receptor Kinase 2/metabolism ; G-Protein-Coupled Receptor Kinase 3/metabolism ; HEK293 Cells ; Humans ; Kinetics ; Phosphorylation ; Protein Binding ; Protein Interaction Domains and Motifs ; Protein Transport ; Receptors, CXCR/agonists ; Receptors, CXCR/genetics ; beta-Arrestin 1/genetics ; beta-Arrestin 2/genetics

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Skocz do pozycji: 9.

Tytuł:: Structural Insights into M1 Muscarinic Acetylcholine Receptor Signaling Bias between Gαq and β-Arrestin through BRET Assays and Molecular Docking.
Autorzy:: Wang D; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.; Academy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Yao Y; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.; Academy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Wang S; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.; Academy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Hou Y; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.; Academy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Zhao L; Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Wang H; Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.; Shanghai Universities Collaborative Innovation Center for Translational Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Chen H; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.; Shanghai Frontiers Science Center of TCM Chemical Biology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Xu J; Academy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.; Shanghai Frontiers Science Center of TCM Chemical Biology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 16; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 16.
Typ publikacji:: Journal Article
MeSH Terms:: Receptor, Muscarinic M1*/metabolism
Acetylcholine*
Humans ; beta-Arrestins/metabolism ; Molecular Docking Simulation ; (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride ; Pilocarpine/pharmacology ; GTP-Binding Proteins/metabolism ; beta-Arrestin 2/metabolism ; beta-Arrestin 1/metabolism ; Energy Transfer ; HEK293 Cells

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Skocz do pozycji: 10.

Tytuł:: Delineation of G Protein-Coupled Receptor Kinase Phosphorylation Sites within the D 1 Dopamine Receptor and Their Roles in Modulating β-Arrestin Binding and Activation.
Autorzy:: Moritz AE; Molecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 35 Convent Drive, Bethesda, MD 20892, USA.
Madaras NS; Molecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 35 Convent Drive, Bethesda, MD 20892, USA.
Rankin ML; Molecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 35 Convent Drive, Bethesda, MD 20892, USA.
Inbody LR; Molecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 35 Convent Drive, Bethesda, MD 20892, USA.
Sibley DR; Molecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 35 Convent Drive, Bethesda, MD 20892, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 01; Vol. 24 (7). Date of Electronic Publication: 2023 Apr 01.
Typ publikacji:: Journal Article
MeSH Terms:: Receptors, Dopamine*/metabolism
Arrestins*/metabolism
Phosphorylation ; beta-Arrestins/metabolism ; G-Protein-Coupled Receptor Kinases/metabolism ; beta-Arrestin 1/metabolism ; Receptors, G-Protein-Coupled/metabolism ; beta-Arrestin 2/metabolism

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Skocz do pozycji: 11.

Tytuł:: Proximity Labeling to Identify β-Arrestin1 Binding Partners Downstream of Ligand-Activated G Protein-Coupled Receptors.
Autorzy:: Zhuo Y; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Robleto VL; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Marchese A; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 07; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 07.
Typ publikacji:: Journal Article
MeSH Terms:: Arrestins*/metabolism
Receptors, G-Protein-Coupled*/metabolism
beta-Arrestin 1/metabolism ; Ligands ; beta-Arrestins/metabolism ; beta-Arrestin 2/metabolism

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Skocz do pozycji: 12.

Tytuł:: Cannabinoid 1 (CB 1 ) receptor arrestin subtype-selectivity and phosphorylation dependence.
Autorzy:: Manning JJ; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Rawcliffe G; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Finlay DB; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Glass M; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2023 Feb; Vol. 180 (3), pp. 369-382. Date of Electronic Publication: 2022 Nov 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Arrestins*/metabolism
Phosphorylation*
Receptor, Cannabinoid, CB1*/metabolism
beta-Arrestin 1/metabolism ; beta-Arrestin 2/metabolism ; beta-Arrestins/metabolism ; Cannabinoids/metabolism ; GTP-Binding Proteins/metabolism ; Humans

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Skocz do pozycji: 13.

Tytuł:: Agonist dependency of the second phase access of β-arrestin 2 to the heteromeric µ-V1b receptor.
Autorzy:: Ngamlertwong N; Division of Molecular Pharmacology, Department of Pharmacology, Jichi Medical University, Tochigi, 329-0498, Japan.
Tsuchiya H; Division of Molecular Pharmacology, Department of Pharmacology, Jichi Medical University, Tochigi, 329-0498, Japan.
Mochimaru Y; Division of Molecular Pharmacology, Department of Pharmacology, Jichi Medical University, Tochigi, 329-0498, Japan.
Azuma M; Division of Molecular Pharmacology, Department of Pharmacology, Jichi Medical University, Tochigi, 329-0498, Japan.
Kuchimaru T; Center for Molecular Medicine, Jichi Medical University, Tochigi, 329-0498, Japan.
Koshimizu TA; Division of Molecular Pharmacology, Department of Pharmacology, Jichi Medical University, Tochigi, 329-0498, Japan. t_.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Aug 04; Vol. 11 (1), pp. 15813. Date of Electronic Publication: 2021 Aug 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Analgesics, Opioid/*pharmacology
Morphine/*pharmacology
Receptors, Vasopressin/*metabolism
beta-Arrestin 2/*metabolism
Binding Sites ; Drug Tolerance ; HEK293 Cells ; Humans ; Phosphorylation ; Receptors, Vasopressin/agonists ; beta-Arrestin 2/agonists

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Skocz do pozycji: 14.

Tytuł:: Ubiquitination of GRK2 Is Required for the β-Arrestin-Biased Signaling Pathway of Dopamine D2 Receptors to Activate ERK Kinases.
Autorzy:: Liu H; School of Pharmaceutical Sciences, Guizhou University, Guiyang 550025, China.
Ma H; School of Pharmaceutical Sciences, Guizhou University, Guiyang 550025, China.
Zeng X; School of Pharmaceutical Sciences, Guizhou University, Guiyang 550025, China.
Wu C; School of Pharmaceutical Sciences, Guizhou University, Guiyang 550025, China.
Acharya S; Mitchell Cancer Institute, School of Medicine, University of South Alabama, Mobile, AL 36604, USA.
Sudan SK; Mitchell Cancer Institute, School of Medicine, University of South Alabama, Mobile, AL 36604, USA.
Zhang X; School of Pharmaceutical Sciences, Guizhou University, Guiyang 550025, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 12; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 12.
Typ publikacji:: Journal Article
MeSH Terms:: G-Protein-Coupled Receptor Kinase 2*/genetics
G-Protein-Coupled Receptor Kinase 2*/metabolism
Signal Transduction*/physiology
beta-Arrestins/metabolism ; beta-Arrestin 1/metabolism ; Receptors, Dopamine D2/genetics ; Receptors, Dopamine D2/metabolism ; Phosphorylation/physiology ; Dopamine ; Ubiquitination

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Skocz do pozycji: 15.

Tytuł:: GPCR Binding and JNK3 Activation by Arrestin-3 Have Different Structural Requirements.
Autorzy:: Zheng C; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.
Weinstein LD; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.
Nguyen KK; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.
Grewal A; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.
Gurevich EV; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.
Gurevich VV; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Jun 06; Vol. 12 (12). Date of Electronic Publication: 2023 Jun 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:: Arrestins*/metabolism
Receptors, G-Protein-Coupled*/metabolism
Animals ; beta-Arrestin 2/metabolism ; Phosphorylation/physiology ; Protein Binding/physiology ; Mammals/metabolism

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Skocz do pozycji: 16.

Tytuł:: G Protein-Dependent Activation of the PKA-Erk1/2 Pathway by the Striatal Dopamine D1/D3 Receptor Heteromer Involves Beta-Arrestin and the Tyrosine Phosphatase Shp-2.
Autorzy:: Bono F; Section of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Tomasoni Z; Section of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Mutti V; Section of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Sbrini G; Section of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Kumar R; Seattle Children's Research Institute, 1920 Terry Ave., Seattle, WA 98101, USA.
Longhena F; Section of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Fiorentini C; Section of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Missale C; Section of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2023 Mar 03; Vol. 13 (3). Date of Electronic Publication: 2023 Mar 03.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dopamine*
Levodopa*/pharmacology
Animals ; Mice ; beta-Arrestin 1 ; beta-Arrestins ; GTP-Binding Proteins ; Protein Tyrosine Phosphatase, Non-Receptor Type 11 ; Protein Tyrosine Phosphatases ; Receptors, Dopamine D1 ; Receptors, Dopamine D3

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Tytuł:: CXCR7 ameliorates myocardial infarction as a β-arrestin-biased receptor.
Autorzy:: Ishizuka M; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Harada M; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. .; Department of Advanced Clinical Science and Therapeutics, Graduate School of Medicine, , The University of Tokyo, Tokyo, Japan. .
Nomura S; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Ko T; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Ikeda Y; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Guo J; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Bujo S; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Yanagisawa-Murakami H; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Satoh M; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Yamada S; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Kumagai H; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.; Department of Advanced Translational Research and Medicine in Management of Pulmonary Hypertension, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Motozawa Y; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Hara H; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Fujiwara T; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Sato T; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Takeda N; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Takeda N; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Otsu K; The School of Cardiovascular Medicine and Sciences, King's College London British Heart Foundation Centre of Excellence, London, UK.
Morita H; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Toko H; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.; Department of Advanced Translational Research and Medicine in Management of Pulmonary Hypertension, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Komuro I; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Feb 09; Vol. 11 (1), pp. 3426. Date of Electronic Publication: 2021 Feb 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: MAP Kinase Signaling System*
Myocardial Infarction/*metabolism
Myocardium/*metabolism
Myocytes, Cardiac/*metabolism
Receptors, CXCR/*metabolism
beta-Arrestin 1/*metabolism
Animals ; Mice ; Mice, Knockout ; Myocardial Infarction/genetics ; Myocardial Infarction/pathology ; Myocardium/pathology ; Myocytes, Cardiac/pathology ; Oligopeptides/pharmacology ; Receptors, CXCR/agonists ; Receptors, CXCR/genetics ; beta-Arrestin 1/genetics

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Skocz do pozycji: 18.

Tytuł:: β-arrestin2 recruitment at the β2 adrenergic receptor: A luciferase complementation assay adapted for undergraduate training in pharmacology.
Autorzy:: Ferraiolo M; Neuropharmacology Laboratory, Institute of Neuroscience, UCLouvain, Brussels, Belgium.; Faculty of Pharmacy and Biomedical Sciences, UCLouvain, Brussels, Belgium.
Beckers P; Neuropharmacology Laboratory, Institute of Neuroscience, UCLouvain, Brussels, Belgium.; Faculty of Pharmacy and Biomedical Sciences, UCLouvain, Brussels, Belgium.
Marquet N; Neuropharmacology Laboratory, Institute of Neuroscience, UCLouvain, Brussels, Belgium.
Roumain M; Faculty of Pharmacy and Biomedical Sciences, UCLouvain, Brussels, Belgium.
Ruiz L; Faculty of Pharmacy and Biomedical Sciences, UCLouvain, Brussels, Belgium.
Dupuis N; Laboratory of Molecular Pharmacology, GIGA-Molecular Biology of Disease, ULiège, Liège, Belgium.
Hanson J; Laboratory of Molecular Pharmacology, GIGA-Molecular Biology of Disease, ULiège, Liège, Belgium.
Hermans E; Neuropharmacology Laboratory, Institute of Neuroscience, UCLouvain, Brussels, Belgium.; Faculty of Pharmacy and Biomedical Sciences, UCLouvain, Brussels, Belgium.; Pokaż więcej
Źródło:: Pharmacology research & perspectives [Pharmacol Res Perspect] 2021 Feb; Vol. 9 (1), pp. e00706.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Biological Assay*
Luciferases, Firefly/*metabolism
Pharmacology/*education
Receptors, Adrenergic, beta-2/*metabolism
beta-Arrestin 2/*metabolism
Adrenergic beta-Agonists/pharmacology ; Adrenergic beta-Antagonists/pharmacology ; Education ; HEK293 Cells ; Humans ; Isoproterenol/pharmacology ; Luciferases, Firefly/genetics ; Propranolol/pharmacology ; Receptors, Adrenergic, beta-2/genetics ; Surveys and Questionnaires ; beta-Arrestin 2/genetics

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Skocz do pozycji: 19.

Tytuł:: The incidence of candidate binding sites for β-arrestin in Drosophila neuropeptide GPCRs.
Autorzy:: Taghert PH; Department of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Nov 01; Vol. 17 (11), pp. e0275410. Date of Electronic Publication: 2022 Nov 01 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Drosophila melanogaster*/metabolism
Neuropeptides*/metabolism
Animals ; beta-Arrestins/metabolism ; Arrestin/metabolism ; Drosophila/metabolism ; Incidence ; beta-Arrestin 1/metabolism ; Binding Sites ; Receptors, G-Protein-Coupled/metabolism ; beta-Arrestin 2/metabolism

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Skocz do pozycji: 20.

Tytuł:: Loss of biased signaling at a G protein-coupled receptor in overexpressed systems.
Autorzy:: Li A; Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America.
Liu S; Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America.
Huang R; Department of Biochemistry, Duke University Medical Center, Durham, North Carolina, United States of America.
Ahn S; Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America.
Lefkowitz RJ; Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America.; Department of Biochemistry, Duke University Medical Center, Durham, North Carolina, United States of America.; Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Mar 24; Vol. 18 (3), pp. e0283477. Date of Electronic Publication: 2023 Mar 24 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Signal Transduction*
Receptors, G-Protein-Coupled*/metabolism
Humans ; Angiotensin II/pharmacology ; Angiotensin II/metabolism ; Ligands ; beta-Arrestins/metabolism ; GTP-Binding Proteins/metabolism ; beta-Arrestin 1/metabolism ; Receptor, Angiotensin, Type 1/metabolism ; HEK293 Cells

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