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Tytuł:
Integrating single-cell and spatial transcriptomes reveals COL4A1/2 facilitates the spatial organisation of stromal cells differentiation in breast phyllodes tumours.
Autorzy:
Li X; Department of Pathology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, P.R. China.; Department of Pathology, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, P.R. China.
Yu X; Department of Pathology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, P.R. China.; Department of Pathology, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, P.R. China.
Bi J; Department of Pathology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, P.R. China.; Department of Pathology, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, P.R. China.
Jiang X; Department of Pathology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, P.R. China.; Department of Pathology, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, P.R. China.
Zhang L; Department of Pathology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, P.R. China.; Department of Pathology, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, P.R. China.
Li Z; Department of Surgery, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, P.R. China.; Department of Surgery, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, P.R. China.
Shao M; Department of Pathology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, P.R. China.; Department of Pathology, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, P.R. China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2024 Mar; Vol. 14 (3), pp. e1611.
Typ publikacji:
Journal Article
MeSH Terms:
Phyllodes Tumor*/diagnosis
Phyllodes Tumor*/genetics
Phyllodes Tumor*/metabolism
Breast Neoplasms*/diagnosis
Breast Neoplasms*/genetics
Breast Neoplasms*/metabolism
Humans ; Female ; Transcriptome/genetics ; Stromal Cells/metabolism ; Cell Differentiation/genetics ; Collagen Type IV/genetics ; Collagen Type IV/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
LRPPRC promotes glycolysis by stabilising LDHA mRNA and its knockdown plus glutamine inhibitor induces synthetic lethality via m A modification in triple-negative breast cancer.
Autorzy:
Yu Y; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Deng H; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wang W; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xiao S; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zheng R; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Lv L; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wang H; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Chen J; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhang B; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2024 Feb; Vol. 14 (2), pp. e1583.
Typ publikacji:
Journal Article
MeSH Terms:
Glutamine*/metabolism
Neoplasm Proteins*/genetics
Triple Negative Breast Neoplasms*/drug therapy
Triple Negative Breast Neoplasms*/genetics
Triple Negative Breast Neoplasms*/metabolism
L-Lactate Dehydrogenase*/genetics
Animals ; Humans ; Mice ; Cell Cycle Proteins/metabolism ; Cell Line, Tumor ; DNA-Binding Proteins/genetics ; Glutaminase/genetics ; Glutaminase/metabolism ; Glycolysis/genetics ; Leucine-Rich Repeat Proteins ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Synthetic Lethal Mutations
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Image-guided metabolomics and transcriptomics reveal tumour heterogeneity in luminal A and B human breast cancer beyond glucose tracer uptake.
Autorzy:
Yang Q; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, University Hospital Tuebingen, Tuebingen, Germany.
Deng S; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, University Hospital Tuebingen, Tuebingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', University of Tuebingen, Tuebingen, Germany.
Preibsch H; Department of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Tuebingen, Germany.
Schade TC; Department of Pathology and Neuropathology, University Hospital Tuebingen, Tuebingen, Germany.
Koch A; Department of Women's Health, University Hospital Tuebingen, Tuebingen, Germany.
Berezhnoy G; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, University Hospital Tuebingen, Tuebingen, Germany.
Zizmare L; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, University Hospital Tuebingen, Tuebingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', University of Tuebingen, Tuebingen, Germany.
Fischer A; Department of Pathology and Neuropathology, University Hospital Tuebingen, Tuebingen, Germany.
Gückel B; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', University of Tuebingen, Tuebingen, Germany.; Department of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Tuebingen, Germany.
Staebler A; Department of Pathology and Neuropathology, University Hospital Tuebingen, Tuebingen, Germany.
Hartkopf AD; Department of Women's Health, University Hospital Tuebingen, Tuebingen, Germany.
Pichler BJ; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, University Hospital Tuebingen, Tuebingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', University of Tuebingen, Tuebingen, Germany.; German Cancer Research Center, German Cancer Consortium DKTK, Partner Site Tuebingen, Tuebingen, Germany.
la Fougère C; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', University of Tuebingen, Tuebingen, Germany.; German Cancer Research Center, German Cancer Consortium DKTK, Partner Site Tuebingen, Tuebingen, Germany.; Department of Nuclear Medicine and Clinical Molecular Imaging, University Hospital Tuebingen, Tuebingen, Germany.
Hahn M; Department of Women's Health, University Hospital Tuebingen, Tuebingen, Germany.
Bonzheim I; Department of Pathology and Neuropathology, University Hospital Tuebingen, Tuebingen, Germany.
Nikolaou K; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', University of Tuebingen, Tuebingen, Germany.; Department of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Tuebingen, Germany.; German Cancer Research Center, German Cancer Consortium DKTK, Partner Site Tuebingen, Tuebingen, Germany.
Trautwein C; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, University Hospital Tuebingen, Tuebingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', University of Tuebingen, Tuebingen, Germany.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2024 Feb; Vol. 14 (2), pp. e1550.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/diagnostic imaging
Breast Neoplasms*/genetics
Breast Neoplasms*/metabolism
Humans ; Female ; Fluorodeoxyglucose F18/metabolism ; Gene Expression Profiling ; Acetates ; Serine ; Lipids
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Extracellular vesicles as a promising source of lipid biomarkers for breast cancer detection in blood plasma.
Autorzy:
Dorado E; Faculty of Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
Doria ML; Faculty of Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
Nagelkerke A; Faculty of Engineering, Department of Bioengineering, Department of Materials, Institute of Biomedical Engineering, Imperial College London, London, United Kingdom.
McKenzie JS; Faculty of Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
Maneta-Stavrakaki S; Faculty of Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
Whittaker TE; Faculty of Engineering, Department of Bioengineering, Department of Materials, Institute of Biomedical Engineering, Imperial College London, London, United Kingdom.
Nicholson JK; Institute of Global Health Innovation, Imperial College London, London, United Kingdom.
Coombes RC; Faculty of Medicine, Department of Surgery and Cancer, Imperial College London, London, United Kingdom.
Stevens MM; Faculty of Engineering, Department of Bioengineering, Department of Materials, Institute of Biomedical Engineering, Imperial College London, London, United Kingdom.
Takats Z; Faculty of Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.; PRISM Inserm U1192, University of Lille, Lille, France.; Deparment of Immunomedicine, University of Regensburg, Regensburg, Germany.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Mar; Vol. 13 (3), pp. e12419.
Typ publikacji:
Journal Article
MeSH Terms:
Extracellular Vesicles*
Breast Neoplasms*/diagnosis
Humans ; Female ; Plasma ; Biomarkers ; Glycerophospholipids
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Selective Capsulotomies and Partial Capsulectomy in Implant-Based Breast Reconstruction Revision Surgery.
Autorzy:
Susini P; Plastic Surgery Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Policlinico le Scotte, Via Bracci 16, Siena 53100, Italy.
Marcaccini G; Plastic Surgery Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Policlinico le Scotte, Via Bracci 16, Siena 53100, Italy.
Giardino FR; Plastic Surgery Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Policlinico le Scotte, Via Bracci 16, Siena 53100, Italy.
Pozzi M; Plastic Surgery Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Policlinico le Scotte, Via Bracci 16, Siena 53100, Italy.
Volanti F; Plastic Surgery Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Policlinico le Scotte, Via Bracci 16, Siena 53100, Italy.
Nisi G; Plastic Surgery Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Policlinico le Scotte, Via Bracci 16, Siena 53100, Italy.
Cuomo R; Plastic Surgery Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Policlinico le Scotte, Via Bracci 16, Siena 53100, Italy.
Grimaldi L; Plastic Surgery Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Policlinico le Scotte, Via Bracci 16, Siena 53100, Italy.
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Źródło:
The breast journal [Breast J] 2024 Feb 27; Vol. 2024, pp. 9097040. Date of Electronic Publication: 2024 Feb 27 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/surgery
Mammaplasty*/adverse effects
Breast Implants*/adverse effects
Humans ; Female ; Reoperation ; Implant Capsular Contracture ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mammoplasty Using Modified Superomedial Pedicle Technique in Severely Macromastia and Ptotic Breasts.
Autorzy:
Selamioğlu E; Haliç University, Department of Plastic Reconstructive and Aesthetic Surgery, İstanbul, Türkiye.
Agdoğan Ö; Private Clinic, Plastic Reconstructive and Aesthetic Surgery, İstanbul, Türkiye.
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Źródło:
The breast journal [Breast J] 2024 Feb 15; Vol. 2024, pp. 7635485. Date of Electronic Publication: 2024 Feb 15 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/surgery
Mammaplasty*/methods
Hypertrophy*
Breast/*abnormalities
Humans ; Female ; Treatment Outcome ; Breast/surgery ; Nipples/surgery ; Retrospective Studies
SCR Disease Name:
Gigantomastia
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
NCAPH drives breast cancer progression and identifies a gene signature that predicts luminal a tumour recurrence.
Autorzy:
Mendiburu-Eliçabe M; Instituto de Biología Molecular y Celular del Cáncer (IBMCC-CIC), Universidad de Salamanca/CSIC, Salamanca, Spain.; Biosanitary Research Institute of Salamanca (IBSAL), Salamanca, Spain.
García-Sancha N; Instituto de Biología Molecular y Celular del Cáncer (IBMCC-CIC), Universidad de Salamanca/CSIC, Salamanca, Spain.; Biosanitary Research Institute of Salamanca (IBSAL), Salamanca, Spain.
Corchado-Cobos R; Instituto de Biología Molecular y Celular del Cáncer (IBMCC-CIC), Universidad de Salamanca/CSIC, Salamanca, Spain.; Biosanitary Research Institute of Salamanca (IBSAL), Salamanca, Spain.
Martínez-López A; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense, Madrid, Spain.; San Carlos Health Research Institute (IdISSC), Madrid, Spain.
Chang H; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory (LBNL), Berkeley, California, USA.; Berkeley Biomedical Data Science Center, Lawrence Berkeley National Laboratory (LBNL), Berkeley, California, USA.
Hua Mao J; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory (LBNL), Berkeley, California, USA.; Berkeley Biomedical Data Science Center, Lawrence Berkeley National Laboratory (LBNL), Berkeley, California, USA.
Blanco-Gómez A; Instituto de Biología Molecular y Celular del Cáncer (IBMCC-CIC), Universidad de Salamanca/CSIC, Salamanca, Spain.; Biosanitary Research Institute of Salamanca (IBSAL), Salamanca, Spain.
García-Casas A; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense, Madrid, Spain.; San Carlos Health Research Institute (IdISSC), Madrid, Spain.
Castellanos-Martín A; Instituto de Biología Molecular y Celular del Cáncer (IBMCC-CIC), Universidad de Salamanca/CSIC, Salamanca, Spain.; Biosanitary Research Institute of Salamanca (IBSAL), Salamanca, Spain.
Salvador N; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense, Madrid, Spain.; San Carlos Health Research Institute (IdISSC), Madrid, Spain.
Jiménez-Navas A; Instituto de Biología Molecular y Celular del Cáncer (IBMCC-CIC), Universidad de Salamanca/CSIC, Salamanca, Spain.; Biosanitary Research Institute of Salamanca (IBSAL), Salamanca, Spain.
Pérez-Baena MJ; Instituto de Biología Molecular y Celular del Cáncer (IBMCC-CIC), Universidad de Salamanca/CSIC, Salamanca, Spain.; Biosanitary Research Institute of Salamanca (IBSAL), Salamanca, Spain.
Sánchez-Martín MA; Departamento de Medicina, Universidad de Salamanca, Salamanca, Spain.; Servicio de Transgénesis, Plataforma Nucleus, Universidad de Salamanca, Salamanca, Spain.
Abad-Hernández MDM; Biosanitary Research Institute of Salamanca (IBSAL), Salamanca, Spain.; Departamento de Anatomía Patológica, Universidad de Salamanca, Salamanca, Spain.; Servicio de Anatomía Patológica, Hospital Universitario de Salamanca, Salamanca, Spain.
Carmen SD; Biosanitary Research Institute of Salamanca (IBSAL), Salamanca, Spain.; Departamento de Anatomía Patológica, Universidad de Salamanca, Salamanca, Spain.; Servicio de Anatomía Patológica, Hospital Universitario de Salamanca, Salamanca, Spain.
Claros-Ampuero J; Instituto de Biología Molecular y Celular del Cáncer (IBMCC-CIC), Universidad de Salamanca/CSIC, Salamanca, Spain.; Biosanitary Research Institute of Salamanca (IBSAL), Salamanca, Spain.; Servicio de Oncología, Hospital Universitario de Salamanca, Salamanca, Spain.
Cruz-Hernández JJ; Instituto de Biología Molecular y Celular del Cáncer (IBMCC-CIC), Universidad de Salamanca/CSIC, Salamanca, Spain.; Biosanitary Research Institute of Salamanca (IBSAL), Salamanca, Spain.; Departamento de Medicina, Universidad de Salamanca, Salamanca, Spain.; Servicio de Oncología, Hospital Universitario de Salamanca, Salamanca, Spain.
Rodríguez-Sánchez CA; Instituto de Biología Molecular y Celular del Cáncer (IBMCC-CIC), Universidad de Salamanca/CSIC, Salamanca, Spain.; Biosanitary Research Institute of Salamanca (IBSAL), Salamanca, Spain.; Departamento de Medicina, Universidad de Salamanca, Salamanca, Spain.; Servicio de Oncología, Hospital Universitario de Salamanca, Salamanca, Spain.
García-Cenador MB; Biosanitary Research Institute of Salamanca (IBSAL), Salamanca, Spain.; Departamento de Cirugía, Universidad de Salamanca, Salamanca, Spain.
García-Criado FJ; Biosanitary Research Institute of Salamanca (IBSAL), Salamanca, Spain.; Departamento de Cirugía, Universidad de Salamanca, Salamanca, Spain.
Vicente RS; Departamento de Informática y Automática, Universidad de Salamanca, Salamanca, España.
Castillo-Lluva S; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense, Madrid, Spain.; San Carlos Health Research Institute (IdISSC), Madrid, Spain.
Pérez-Losada J; Instituto de Biología Molecular y Celular del Cáncer (IBMCC-CIC), Universidad de Salamanca/CSIC, Salamanca, Spain.; Biosanitary Research Institute of Salamanca (IBSAL), Salamanca, Spain.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2024 Feb; Vol. 14 (2), pp. e1554.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Humans ; Mice ; Animals ; Female ; Neoplasm Recurrence, Local/genetics ; Gene Expression Profiling ; Prognosis ; Mice, Transgenic ; Nuclear Proteins/genetics ; Cell Cycle Proteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The TGFβ2-Snail1-miRNA TGFβ2 Circuitry is Critical for the Development of Aggressive Functions in Breast Cancer.
Autorzy:
Luo L; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou, China.
Xu N; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou, China.
Fan W; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou, China.
Wu Y; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou, China.
Chen P; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou, China.
Li Z; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou, China.
He Z; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou, China.
Liu H; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou, China.
Lin Y; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou, China.
Zheng G; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2024 Feb; Vol. 14 (2), pp. e1558.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/genetics
MicroRNAs*/genetics
Humans ; Female ; Estrogen Receptor alpha/genetics ; Transforming Growth Factor beta/genetics ; Signal Transduction/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Molecular features of luminal breast cancer defined through spatial and single-cell transcriptomics.
Autorzy:
Yoshitake R; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, USA.
Mori H; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, USA.; Department of Surgery and Oncology, Graduate School of Medicine, Kyushu University, Fukuoka, Japan.
Ha D; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, USA.
Wu X; Integrative Genomics Core, Beckman Research Institute of City of Hope, Monrovia, California, USA.
Wang J; Integrative Genomics Core, Beckman Research Institute of City of Hope, Monrovia, California, USA.
Wang X; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, USA.
Saeki K; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, USA.; Faculty of Veterinary Medicine, Okayama University of Science, Imabari, Ehime, Japan.
Chang G; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, USA.
Shim HJ; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, USA.
Chan Y; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, USA.
Chen S; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, USA.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2024 Jan; Vol. 14 (1), pp. e1548.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/genetics
Breast Neoplasms*/pathology
Humans ; Female ; Ki-67 Antigen/genetics ; Receptors, Estrogen/genetics ; Gene Expression Profiling ; Estrogens ; Inflammation ; Hypoxia
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Eliciting the antitumor immune response with a conditionally activated PD-L1 targeting antibody analyzed with a quantitative systems pharmacology model.
Autorzy:
Ippolito A; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Wang H; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Zhang Y; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Vakil V; Clinical and Quantitative Pharmacology, CytomX Therapeutics, Inc., South San Francisco, California, USA.
Bazzazi H; Clinical and Quantitative Pharmacology, CytomX Therapeutics, Inc., South San Francisco, California, USA.
Popel AS; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Oncology, and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
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Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Jan; Vol. 13 (1), pp. 93-105. Date of Electronic Publication: 2023 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*/antagonists & inhibitors
Triple Negative Breast Neoplasms*/drug therapy
Triple Negative Breast Neoplasms*/pathology
Humans ; Antibodies/pharmacology ; Cell Line, Tumor ; Immunity ; Network Pharmacology ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Multi-MicroRNA Analysis Can Improve the Diagnostic Performance of Mammography in Determining Breast Cancer Risk.
Autorzy:
Song JE; Department of Family Medicine, Kyungpook National University Chilgok Hospital, 807 Hoguk-ro, Buk-gu, Daegu 41404, Republic of Korea.
Jang JY; BIOINFRA Life Science Inc., Jongno-gu, Seoul 03127, Republic of Korea.
Kang KN; BIOINFRA Life Science Inc., Jongno-gu, Seoul 03127, Republic of Korea.
Jung JS; BIOINFRA Life Science Inc., Jongno-gu, Seoul 03127, Republic of Korea.
Kim CW; BIOINFRA Life Science Inc., Jongno-gu, Seoul 03127, Republic of Korea.
Kim AS; Department of Family Medicine, Kyungpook National University Chilgok Hospital, 807 Hoguk-ro, Buk-gu, Daegu 41404, Republic of Korea.
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Źródło:
The breast journal [Breast J] 2023 Dec 27; Vol. 2023, pp. 9117047. Date of Electronic Publication: 2023 Dec 27 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/diagnostic imaging
Breast Neoplasms*/genetics
MicroRNAs*/genetics
Fibrocystic Breast Disease*
Female ; Humans ; Mammography/methods ; Breast ; Biomarkers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Evaluation of a Surgical Navigation System for Localization and Excision of Nonpalpable Lesions in Breast and Axillary Surgery.
Autorzy:
Carlson KA; Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Checka C; Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Hunt KK; Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Breast Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Jung J; Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Bridges C; Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Singh P; Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Refinetti A; Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Moseley T; Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Breast Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Perez F; Department of Breast Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Mayo C; Department of Breast Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Tamirisa N; Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
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Źródło:
The breast journal [Breast J] 2023 Dec 23; Vol. 2023, pp. 9993852. Date of Electronic Publication: 2023 Dec 23 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Surgical Navigation Systems*
Breast Neoplasms*/diagnostic imaging
Breast Neoplasms*/surgery
Breast Neoplasms*/pathology
Humans ; Female ; Pilot Projects ; Lymph Nodes/pathology ; Lymph Node Excision/methods ; Sentinel Lymph Node Biopsy ; Axilla/diagnostic imaging ; Axilla/surgery
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MLLT11 siRNA Inhibits the Migration and Promotes the Apoptosis of MDA-MB-231 Breast Cancer Cells.
Autorzy:
Liu X; Shanxi Province Cancer Hospital, Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences, Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan 030001, China.
Bai W; Breast Surgery, The Second Hospital of Shanxi Medical University, Taiyuan 030001, China.
Li J; Shanxi Province Cancer Hospital, Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences, Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan 030001, China.
Ma J; Shanxi Province Cancer Hospital, Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences, Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan 030001, China.
Liu Y; Shanxi Medical University, Taiyuan 030006, China.
Wang Z; Shanxi Medical University, Taiyuan 030006, China.
Hu L; Shanxi Medical University, Taiyuan 030006, China.
Li Z; Shanxi Medical University, Taiyuan 030006, China.
Papukashvili D; Southern University of Science and Technology, Shenzhen 518055, China.
Rcheulishvili N; Southern University of Science and Technology, Shenzhen 518055, China.
Wang F; Breast Surgery, The Second Hospital of Shanxi Medical University, Taiyuan 030001, China.
Lu X; Shanxi Province Cancer Hospital, Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences, Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan 030001, China.
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Źródło:
The breast journal [Breast J] 2023 Dec 01; Vol. 2023, pp. 6282654. Date of Electronic Publication: 2023 Dec 01 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/genetics
Breast Neoplasms*/pathology
Female ; Humans ; Apoptosis ; Cell Line, Tumor ; Cell Proliferation ; MDA-MB-231 Cells ; Neoplasm Invasiveness/pathology ; Neoplasm Proteins/pharmacology ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/pharmacology ; Transcription Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
C9orf142 transcriptionally activates MTBP to drive progression and resistance to CDK4/6 inhibitor in triple-negative breast cancer.
Autorzy:
Liao L; Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Cancer Institute, Shanghai Medical College, Fudan University, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Deng L; Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Zhang YL; Cancer Institute, Shanghai Medical College, Fudan University, Shanghai, China.
Yang SY; Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Cancer Institute, Shanghai Medical College, Fudan University, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Andriani L; Department of Breast Surgery, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.
Hu SY; Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Zhang FL; Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Cancer Institute, Shanghai Medical College, Fudan University, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Shao ZM; Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Cancer Institute, Shanghai Medical College, Fudan University, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.; Department of Breast Surgery, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Breast Cancer, Shanghai Medical College, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Radiation Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Li DQ; Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Cancer Institute, Shanghai Medical College, Fudan University, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.; Department of Breast Surgery, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Breast Cancer, Shanghai Medical College, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Radiation Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2023 Nov; Vol. 13 (11), pp. e1480.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Triple Negative Breast Neoplasms*/drug therapy
Triple Negative Breast Neoplasms*/genetics
Triple Negative Breast Neoplasms*/pathology
Humans ; Animals ; Mice ; Cell Line, Tumor ; Cell Proliferation/genetics ; Up-Regulation/genetics ; Carrier Proteins/genetics ; Cyclin-Dependent Kinase 4/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Idiopathic Granulomatous Mastitis.
Autorzy:
Dilaveri C; Mayo Clinic, Department of Medicine, Division of General Internal Medicine, Rochester, USA.
Degnim A; Mayo Clinic, Department of Surgery, Division of Breast and Melanoma Surgical Oncology, Rochester, USA.
Lee C; Mayo Clinic, Department of Radiology, Division of Breast Imaging and Intervention, Rochester, USA.
DeSimone D; Mayo Clinic, Department of Medicine, Division of Infectious Diseases, Rochester, USA.
Moldoveanu D; Mayo Clinic, Department of Surgery, Division of Breast and Melanoma Surgical Oncology, Rochester, USA.
Ghosh K; Mayo Clinic, Department of Medicine, Division of General Internal Medicine, Rochester, USA.
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Źródło:
The breast journal [Breast J] 2024 Jan 25; Vol. 2024, pp. 6693720. Date of Electronic Publication: 2024 Jan 25 (Print Publication: 2024).
Typ publikacji:
Journal Article; Review
MeSH Terms:
Granulomatous Mastitis*/diagnosis
Granulomatous Mastitis*/drug therapy
Breast Neoplasms*/diagnosis
Female ; Humans ; Adult ; Neoplasm Recurrence, Local ; Breast/pathology ; Steroids
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Clinicopathological Features and Prognostic Significance of HER2-Low in Early Breast Tumors Patients Prognostic Comparison of HER-Low and HER2-Negative Breast Cancer Stratified by Hormone Receptor Status.
Autorzy:
Gamrani S; Medical Center of Biomedical and Translational Research, Hassan II University Hospital, Faculty of Medicine and Pharmacy, University Sidi Mohamed Ben Abdellah, Fez, Morocco.; Laboratory of Anatomic Pathology and Molecular Pathology, University Hospital Hassan II, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
Akhouayri L; Dipartimento di Scienze Cliniche e Biologiche, Università Degli Studi Di Torino, Via Giuseppe Verdi, Torino, Italy.; Department of Biomedical Sciences, Genetics and Molecular Biology Laboratory, Faculty of Medicine and Pharmacy, Hassan II-Casablanca University, Rue Tariq Ibn Ziad, Casablanca, Morocco.
Boukansa S; Medical Center of Biomedical and Translational Research, Hassan II University Hospital, Faculty of Medicine and Pharmacy, University Sidi Mohamed Ben Abdellah, Fez, Morocco.; Laboratory of Anatomic Pathology and Molecular Pathology, University Hospital Hassan II, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
Karkouri M; Department of Biomedical Sciences, Genetics and Molecular Biology Laboratory, Faculty of Medicine and Pharmacy, Hassan II-Casablanca University, Rue Tariq Ibn Ziad, Casablanca, Morocco.; Department of Pathology, Ibn Rochd University Hospital, Rue des Hôpitaux, Casablanca, Morocco.
El Fatemi H; Medical Center of Biomedical and Translational Research, Hassan II University Hospital, Faculty of Medicine and Pharmacy, University Sidi Mohamed Ben Abdellah, Fez, Morocco.; Laboratory of Anatomic Pathology and Molecular Pathology, University Hospital Hassan II, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
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Źródło:
The breast journal [Breast J] 2023 Nov 30; Vol. 2023, pp. 6621409. Date of Electronic Publication: 2023 Nov 30 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/pathology
Humans ; Female ; Prognosis ; Biomarkers, Tumor/analysis ; Receptor, ErbB-2/analysis ; Retrospective Studies ; In Situ Hybridization, Fluorescence ; Receptors, Progesterone
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Association between ER, PR, HER2, and ER-/PR+ Expression and Lung Cancer Subsequent in Breast Cancer Patients: A Retrospective Cohort Study Based on SEER Database.
Autorzy:
Shao HY; Department of CT/MR, Xingtai People's Hospital, Xingtai, Hebei, China.
Hao BT; Department of Thoracic Surgery, Xingtai People's Hospital, Xingtai, Hebei, China.
Gao FX; Department of CT/MR, Xingtai People's Hospital, Xingtai, Hebei, China.
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Źródło:
The breast journal [Breast J] 2023 Nov 11; Vol. 2023, pp. 7028189. Date of Electronic Publication: 2023 Nov 11 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Lung Neoplasms*/epidemiology
Humans ; Female ; Male ; Biomarkers, Tumor/metabolism ; Receptors, Estrogen/metabolism ; Retrospective Studies ; Receptors, Progesterone/metabolism ; Receptor, ErbB-2/metabolism ; Prognosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Human-Mimic Submuscular and Premuscular Irradiated Rat Model: Histologic Characteristics of the Capsule Tissue in Contact with the Breast Implant.
Autorzy:
Kim HB; Department of Plastic and Reconstructive Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Han SY; Department of Plastic and Reconstructive Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Eom JS; Department of Plastic and Reconstructive Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Han HH; Department of Plastic and Reconstructive Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
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Źródło:
The breast journal [Breast J] 2023 Nov 09; Vol. 2023, pp. 4363272. Date of Electronic Publication: 2023 Nov 09 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Breast Implants*
Breast Neoplasms*
Breast Implantation*/methods
Mammaplasty*/methods
Acellular Dermis*
Humans ; Rats ; Animals ; Female ; Rats, Sprague-Dawley ; Silicones
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Oncogenic PIK3CA recruits myeloid-derived suppressor cells to shape the immunosuppressive tumour microenvironment in luminal breast cancer through the 5-lipoxygenase-dependent arachidonic acid pathway.
Autorzy:
Li X; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.; Department of Thyroid and Neck, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China.
Chen G; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
Wang F; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
Guo X; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.; Department of Breast Pathology and Lab, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Zhang R; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
Liu P; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
Dong L; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
Yu W; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.
Wang H; College of Life Sciences, Nankai University, Tianjin, China.
Wang H; Laboratory of Cancer Cell Biology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Caner, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.
Yu J; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2023 Nov; Vol. 13 (11), pp. e1483.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/metabolism
Myeloid-Derived Suppressor Cells*
Female ; Humans ; Arachidonate 5-Lipoxygenase/genetics ; Arachidonate 5-Lipoxygenase/metabolism ; Arachidonic Acid/metabolism ; Class I Phosphatidylinositol 3-Kinases/genetics ; Class I Phosphatidylinositol 3-Kinases/metabolism ; Immunosuppressive Agents ; Leukotriene B4/metabolism ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Model-based prediction of effective target exposure for MEN1611 in combination with trastuzumab in HER2-positive advanced or metastatic breast cancer patients.
Autorzy:
Tosca EM; Laboratory of Bioinformatics, Mathematical Modelling and Synthetic Biology, Department of Electrical, Computer and Biomedical Engineering, Università degli Studi di Pavia, Pavia, Italy.
Borella E; Clinical Pharmacology Department, Menarini Stemline, Florence, Italy.
Piana C; Clinical Pharmacology Department, Menarini Stemline, Florence, Italy.
Bouchene S; Clinical Pharmacology Department, Menarini Stemline, Florence, Italy.
Merlino G; Experimental and Translational Oncology Department, Menarini Stemline, Pomezia, Italy.
Fiascarelli A; Experimental and Translational Oncology Department, Menarini Stemline, Pomezia, Italy.
Mazzei P; Clinical Pharmacology Department, Menarini Stemline, Florence, Italy.
Magni P; Laboratory of Bioinformatics, Mathematical Modelling and Synthetic Biology, Department of Electrical, Computer and Biomedical Engineering, Università degli Studi di Pavia, Pavia, Italy.
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Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2023 Nov; Vol. 12 (11), pp. 1626-1639. Date of Electronic Publication: 2023 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/metabolism
Humans ; Animals ; Mice ; Female ; Trastuzumab/pharmacology ; Trastuzumab/therapeutic use ; Phosphatidylinositol 3-Kinases/therapeutic use ; Receptor, ErbB-2/metabolism ; Protein Kinase Inhibitors/therapeutic use ; Angiogenesis Inhibitors/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/pharmacokinetics
Czasopismo naukowe
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