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Tytuł :
Expression and prognosis analyses of CASP1 in acute myeloid leukemia.
Autorzy :
Liu J; The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen 518107, Guangdong, People's Republic of China.
Zhao M; The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen 518107, Guangdong, People's Republic of China.
Feng X; The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen 518107, Guangdong, People's Republic of China.
Zeng Y; The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen 518107, Guangdong, People's Republic of China.
Lin D; The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen 518107, Guangdong, People's Republic of China.
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Źródło :
Aging [Aging (Albany NY)] 2021 May 17; Vol. 13 (10), pp. 14088-14108. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Leukemic*/drug effects
Caspase 1/*genetics
Leukemia, Myeloid, Acute/*genetics
Caspase 1/metabolism ; Caspase Inhibitors/pharmacology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Continental Population Groups ; Gene Ontology ; Gene Regulatory Networks/drug effects ; Humans ; Leukemia, Myeloid, Acute/enzymology ; Leukemia, Myeloid, Acute/pathology ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Molecular Sequence Annotation ; Prognosis ; Protein Kinases/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Transcription Factors/metabolism ; Transcription, Genetic/drug effects
Czasopismo naukowe
Tytuł :
Efficient synthesis, biological evaluation, and docking study of isatin based derivatives as caspase inhibitors.
Autorzy :
Firoozpour L; Drug Design and Development Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran.
Gao L; National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Moghimi S; Drug Design and Development Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran.
Pasalar P; Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Davoodi J; Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
Wang MW; National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Rezaei Z; Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Dadgar A; Pharmaceutical Sciences Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Yahyavi H; Drug Design and Development Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran.
Amanlou M; Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Foroumadi A; Drug Design and Development Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran.; Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 1674-1684.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Docking Simulation*
Caspase Inhibitors/*pharmacology
Isatin/*pharmacology
Sulfonamides/*pharmacology
Caspase 3 ; Caspase 7 ; Caspase Inhibitors/chemical synthesis ; Caspase Inhibitors/chemistry ; Dose-Response Relationship, Drug ; Humans ; Isatin/chemistry ; Molecular Structure ; Structure-Activity Relationship ; Sulfonamides/chemistry
Czasopismo naukowe
Tytuł :
Caspase-8 loss radiosensitizes head and neck squamous cell carcinoma to SMAC mimetic-induced necroptosis.
Autorzy :
Uzunparmak B; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, Texas USA.
Gao M; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Lindemann A; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Erikson K; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Wang L; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Lin E; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Frank SJ; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Gleber-Netto FO; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Zhao M; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Skinner HD; Department of Radiation Oncology, University of Pittsburgh Hillman Cancer Center, Pittsburgh, Pennsylvania, USA.
Newton J; Bobby R. Alford Department of Otolaryngology - Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USA.
Sikora AG; Bobby R. Alford Department of Otolaryngology - Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USA.
Myers JN; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Pickering CR; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
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Źródło :
JCI insight [JCI Insight] 2020 Dec 03; Vol. 5 (23). Date of Electronic Publication: 2020 Dec 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Caspase 8/*metabolism
Necroptosis/*physiology
Squamous Cell Carcinoma of Head and Neck/*metabolism
Apoptosis/drug effects ; Apoptosis Regulatory Proteins/metabolism ; Biomimetics ; Caspase 8/genetics ; Caspase 8/physiology ; Caspase Inhibitors/metabolism ; Caspase Inhibitors/pharmacology ; Caspases/metabolism ; Cell Line, Tumor ; Databases, Genetic ; Dipeptides/metabolism ; Dipeptides/pharmacology ; Humans ; Indoles/metabolism ; Indoles/pharmacology ; Intracellular Signaling Peptides and Proteins/metabolism ; Mitochondria/metabolism ; Mitochondrial Proteins/metabolism ; Necroptosis/genetics ; Squamous Cell Carcinoma of Head and Neck/genetics
Czasopismo naukowe
Tytuł :
Characterizing caspase-1 involvement during esophageal disease progression.
Autorzy :
Barber G; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.; Department of Surgery, Trinity Translational Medicine Institute, Trinity College and St. James's Hospital Dublin, Dublin 8, Ireland.
Anand A; Department of Internal Medicine, Technical University of Munich, Munich, Germany.
Katarzyna Oficjalska; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.
Phelan JJ; Department of Surgery, Trinity Translational Medicine Institute, Trinity College and St. James's Hospital Dublin, Dublin 8, Ireland.
Heeran AB; Department of Surgery, Trinity Translational Medicine Institute, Trinity College and St. James's Hospital Dublin, Dublin 8, Ireland.
Flis E; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.
Clarke NE; Department of Surgery, Trinity Translational Medicine Institute, Trinity College and St. James's Hospital Dublin, Dublin 8, Ireland.
Watson JA; Royal College of Surgeons in Ireland and Beaumont Hospital, Dublin 9, Ireland.
Strangmann J; Department of Internal Medicine, Technical University of Munich, Munich, Germany.
Flood B; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.
O'Neill H; Department of Surgery, Trinity Translational Medicine Institute, Trinity College and St. James's Hospital Dublin, Dublin 8, Ireland.
O'Toole D; National Oesophageal and Gastric Centre, St. James's Hospital, Dublin 8, Ireland.
MacCarthy F; National Oesophageal and Gastric Centre, St. James's Hospital, Dublin 8, Ireland.
Ravi N; Department of Surgery, Trinity Translational Medicine Institute, Trinity College and St. James's Hospital Dublin, Dublin 8, Ireland.; National Oesophageal and Gastric Centre, St. James's Hospital, Dublin 8, Ireland.
Reynolds JV; Department of Surgery, Trinity Translational Medicine Institute, Trinity College and St. James's Hospital Dublin, Dublin 8, Ireland.; National Oesophageal and Gastric Centre, St. James's Hospital, Dublin 8, Ireland.
Kay EW; Royal College of Surgeons in Ireland and Beaumont Hospital, Dublin 9, Ireland.
Quante M; Department of Internal Medicine, Technical University of Munich, Munich, Germany.
O'Sullivan J; Department of Surgery, Trinity Translational Medicine Institute, Trinity College and St. James's Hospital Dublin, Dublin 8, Ireland. .
Creagh EM; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2020 Dec; Vol. 69 (12), pp. 2635-2649. Date of Electronic Publication: 2020 Jul 01.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma/*immunology
Barrett Esophagus/*immunology
Caspase 1/*metabolism
Esophageal Mucosa/*pathology
Esophageal Neoplasms/*immunology
Inflammasomes/*immunology
Adenocarcinoma/pathology ; Adenocarcinoma/surgery ; Aged ; Animals ; Barrett Esophagus/genetics ; Barrett Esophagus/pathology ; Biopsy ; Caspase 1/immunology ; Caspase Inhibitors/pharmacology ; Cell Line, Tumor ; Cells, Cultured ; Chemokine CXCL1/metabolism ; Disease Models, Animal ; Disease Progression ; Esophageal Mucosa/cytology ; Esophageal Mucosa/immunology ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/surgery ; Esophagectomy ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Expression Regulation, Neoplastic/immunology ; Humans ; Inflammasomes/metabolism ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Male ; Mice ; Mice, Transgenic ; Middle Aged ; Primary Cell Culture ; Signal Transduction/drug effects ; Signal Transduction/immunology
SCR Disease Name :
Adenocarcinoma Of Esophagus
Czasopismo naukowe
Tytuł :
ConBr lectin modulates MAPKs and Akt pathways and triggers autophagic glioma cell death by a mechanism dependent upon caspase-8 activation.
Autorzy :
Wolin IAV; Departamento de Bioquímica e Programa de Pós-graduação Em Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, 88040-900, Florianópolis, Santa Catarina, Brazil.
Heinrich IA; Departamento de Bioquímica e Programa de Pós-graduação Em Neurociências, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, 88040-900, Florianópolis, Santa Catarina, Brazil.
Nascimento APM; Departamento de Bioquímica e Programa de Pós-graduação Em Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, 88040-900, Florianópolis, Santa Catarina, Brazil.
Welter PG; Departamento de Bioquímica e Programa de Pós-graduação Em Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, 88040-900, Florianópolis, Santa Catarina, Brazil.
Sosa LDV; Centro de Microscopía Electrónica, Universidad Nacional de Córdoba, Facultad de Ciencias Médicas, Ciudad Universitaria, 5000, Córdoba, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Investigaciones en Ciencias de La Salud (INICSA), Córdoba, Argentina.
De Paul AL; Centro de Microscopía Electrónica, Universidad Nacional de Córdoba, Facultad de Ciencias Médicas, Ciudad Universitaria, 5000, Córdoba, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Investigaciones en Ciencias de La Salud (INICSA), Córdoba, Argentina.
Zanotto-Filho A; Departamento de Farmacologia e Programa de Pós-graduação Em Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, 88040-900, Florianópolis, Santa Catarina, Brazil.
Nedel CB; Departamento de Biologia Celular, Embriologia e Genética, Laboratório de Biologia Celular de Gliomas, Programa de Pós-graduação Em Biologia Celular e Do Desenvolvimento, Universidade Federal de Santa Catarina, Campus Universitário, 88040-900, Florianópolis, Santa Catarina, Brazil.
Lima LD; Departamento de Bioquímica e Biologia Molecular, BioMolLab, Universidade Federal Do Ceará, CEP, 60020-181, Fortaleza, Ceará, Brazil.
Osterne VJS; Departamento de Bioquímica e Biologia Molecular, BioMolLab, Universidade Federal Do Ceará, CEP, 60020-181, Fortaleza, Ceará, Brazil.
Pinto-Junior VR; Departamento de Física, Universidade Federal Do Ceará, Fortaleza, Ceará, Brazil.
Nascimento KS; Departamento de Bioquímica e Biologia Molecular, BioMolLab, Universidade Federal Do Ceará, CEP, 60020-181, Fortaleza, Ceará, Brazil.
Cavada BS; Departamento de Bioquímica e Biologia Molecular, BioMolLab, Universidade Federal Do Ceará, CEP, 60020-181, Fortaleza, Ceará, Brazil.
Leal RB; Departamento de Bioquímica e Programa de Pós-graduação Em Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, 88040-900, Florianópolis, Santa Catarina, Brazil; Departamento de Bioquímica e Programa de Pós-graduação Em Neurociências, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, 88040-900, Florianópolis, Santa Catarina, Brazil. Electronic address: .
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Źródło :
Biochimie [Biochimie] 2021 Jan; Vol. 180, pp. 186-204. Date of Electronic Publication: 2020 Nov 07.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Caspase 8/*metabolism
Enzyme Activation/*drug effects
Glioma/*drug therapy
MAP Kinase Signaling System/*drug effects
Plant Lectins/*pharmacology
Animals ; Apoptosis/drug effects ; Astrocytes/drug effects ; Autophagy/drug effects ; Caspase 3/metabolism ; Cell Death/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Survival/drug effects ; Glioma/metabolism ; Glioma/pathology ; Humans ; Mice ; Mitochondria/drug effects ; Mitogen-Activated Protein Kinases/metabolism ; Molecular Docking Simulation ; Polysaccharides/metabolism ; Protein Domains/physiology ; Protein Structure, Quaternary/physiology ; Protein Structure, Tertiary/physiology ; Proto-Oncogene Proteins c-akt/metabolism ; Rats
Czasopismo naukowe
Tytuł :
Riboflavin, vitamin B2, attenuates NLRP3, NLRC4, AIM2, and non-canonical inflammasomes by the inhibition of caspase-1 activity.
Autorzy :
Ahn H; Laboratory of Inflammatory Diseases, Department of Physiology, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Lee GS; Laboratory of Inflammatory Diseases, Department of Physiology, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea. .
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Źródło :
Scientific reports [Sci Rep] 2020 Nov 05; Vol. 10 (1), pp. 19091. Date of Electronic Publication: 2020 Nov 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Caspase 1/*metabolism
Inflammasomes/*drug effects
Inflammasomes/*metabolism
Riboflavin/*pharmacology
Animals ; Anti-Inflammatory Agents/pharmacology ; Apoptosis Regulatory Proteins/metabolism ; Calcium-Binding Proteins/metabolism ; Caspase Inhibitors/pharmacology ; Cells, Cultured ; DNA-Binding Proteins/metabolism ; Female ; Humans ; Inflammasomes/immunology ; Interleukin-18/biosynthesis ; Interleukin-1beta/biosynthesis ; Macrophages, Peritoneal/drug effects ; Macrophages, Peritoneal/metabolism ; Mice ; Mice, Inbred C57BL ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; THP-1 Cells
Czasopismo naukowe
Tytuł :
Casp8 acts through A20 to inhibit PD-L1 expression: The mechanism and its implication in immunotherapy.
Autorzy :
Zou J; Department of Abdominal Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.; Laboratory of Molecular Targeted Therapy in Oncology, West China Hospital, Sichuan University, Chengdu, China.
Xia H; Department of Abdominal Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.; Laboratory of Molecular Targeted Therapy in Oncology, West China Hospital, Sichuan University, Chengdu, China.
Zhang C; Laboratory of Molecular Targeted Therapy in Oncology, West China Hospital, Sichuan University, Chengdu, China.
Xu H; Department of Abdominal Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.; Laboratory of Molecular Targeted Therapy in Oncology, West China Hospital, Sichuan University, Chengdu, China.
Tang Q; Laboratory of Molecular Targeted Therapy in Oncology, West China Hospital, Sichuan University, Chengdu, China.
Zhu G; Department of Abdominal Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.; Laboratory of Molecular Targeted Therapy in Oncology, West China Hospital, Sichuan University, Chengdu, China.
Li J; Department of Abdominal Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Bi F; Department of Abdominal Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.; Laboratory of Molecular Targeted Therapy in Oncology, West China Hospital, Sichuan University, Chengdu, China.
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Źródło :
Cancer science [Cancer Sci] 2021 Jul; Vol. 112 (7), pp. 2664-2678. Date of Electronic Publication: 2021 May 20.
Typ publikacji :
Journal Article
MeSH Terms :
B7-H1 Antigen/*metabolism
Caspase 8/*physiology
Immunotherapy, Adoptive/*methods
Melanoma/*therapy
Tumor Necrosis Factor alpha-Induced Protein 3/*metabolism
Animals ; B7-H1 Antigen/genetics ; CTLA-4 Antigen/metabolism ; Caspase 8/genetics ; Cell Line, Tumor ; Disease Progression ; Down-Regulation ; GTPase-Activating Proteins/metabolism ; Interferon-gamma/metabolism ; Killer Cells, Natural/immunology ; Killer Cells, Natural/metabolism ; Lysosome-Associated Membrane Glycoproteins/metabolism ; Melanoma/immunology ; Melanoma/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Nude ; NF-kappa B/metabolism ; Ubiquitination ; Up-Regulation
Czasopismo naukowe
Tytuł :
Caspase-3, a shrimp phosphorylated hemocytic protein is necessary to control YHV infection.
Autorzy :
Havanapan PO; Institute of Molecular Biosciences, Mahidol University, Salaya Campus, Phutthamonthon 4 Rd, Salaya, Nakhon Pathom, 73170, Thailand.
Taengchaiyaphum S; Aquatic Animal Health Research Team (AQHT), Integrative Aquaculture Biotechnology Research Group, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, 12120, Thailand.
Paemanee A; National Omics Center, National Science and Technology Development Agency (NSTDA), Pathum Thani, 12120, Thailand.
Phungthanom N; Institute of Molecular Biosciences, Mahidol University, Salaya Campus, Phutthamonthon 4 Rd, Salaya, Nakhon Pathom, 73170, Thailand.
Roytrakul S; Functional Ingredients and Food Innovation Research Group, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, 12120, Thailand.
Sritunyalucksana K; Aquatic Animal Health Research Team (AQHT), Integrative Aquaculture Biotechnology Research Group, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, 12120, Thailand.
Krittanai C; Institute of Molecular Biosciences, Mahidol University, Salaya Campus, Phutthamonthon 4 Rd, Salaya, Nakhon Pathom, 73170, Thailand. Electronic address: .
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Źródło :
Fish & shellfish immunology [Fish Shellfish Immunol] 2021 Jul; Vol. 114, pp. 36-48. Date of Electronic Publication: 2021 Apr 14.
Typ publikacji :
Journal Article
MeSH Terms :
Roniviridae*
Caspase 3/*metabolism
Hemocytes/*enzymology
Penaeidae/*virology
Animals ; Caspase 3/genetics ; Gene Expression Regulation, Enzymologic/immunology ; Host-Pathogen Interactions/immunology ; Host-Pathogen Interactions/physiology
Czasopismo naukowe
Tytuł :
Bmcas-1 plays an important role in response against BmNPV infection in vitro.
Autorzy :
Wang X; Jiangsu Key Laboratory of Sericultural Biology and Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, China.
Zhao ZQ; Jiangsu Key Laboratory of Sericultural Biology and Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, China.
Huang XM; Jiangsu Key Laboratory of Sericultural Biology and Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, China.
Ding XY; Jiangsu Key Laboratory of Sericultural Biology and Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, China.
Zhao CX; Jiangsu Key Laboratory of Sericultural Biology and Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, China.
Li MW; Jiangsu Key Laboratory of Sericultural Biology and Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, China.; Key Laboratory of Silkworm and Mulberry Genetic Improvement, Ministry of Agriculture and Rural Affairs, Sericultural Research Institute, Chinese Academy of Agricultural Science, Zhenjiang, Jiangsu, China.
Wu YC; Jiangsu Key Laboratory of Sericultural Biology and Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, China.; Key Laboratory of Silkworm and Mulberry Genetic Improvement, Ministry of Agriculture and Rural Affairs, Sericultural Research Institute, Chinese Academy of Agricultural Science, Zhenjiang, Jiangsu, China.
Liu QN; Jiangsu Key Laboratory for Bioresources of Saline Soils, Jiangsu Synthetic Innovation Center for Coastal Bio-agriculture, Jiangsu Provincial Key Laboratory of Coastal Wetland Bioresources and Environmental Protection, School of Wetland, Yancheng, Jiangsu, China.
Wang XY; Jiangsu Key Laboratory of Sericultural Biology and Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, China.
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Źródło :
Archives of insect biochemistry and physiology [Arch Insect Biochem Physiol] 2021 Jul; Vol. 107 (3), pp. e21793. Date of Electronic Publication: 2021 May 05.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Bombyx/*virology
Caspase 1/*metabolism
Host-Pathogen Interactions/*immunology
Nucleopolyhedroviruses/*immunology
Animals ; Bombyx/enzymology ; Bombyx/immunology ; Caspase 1/immunology ; Green Fluorescent Proteins
SCR Organism :
Bombyx mori nucleopolyhedrovirus
Czasopismo naukowe
Tytuł :
In Situ Imaging of Cellular Reactive Oxygen Species and Caspase-3 Activity Using a Multifunctional Theranostic Probe for Cancer Diagnosis and Therapy.
Autorzy :
Wang K; Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.; State Key Laboratory of Bioelectronics, Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.
Zhang F; State Key Laboratory of Bioelectronics, Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.
Wei Y; State Key Laboratory of Bioelectronics, Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.
Wei W; State Key Laboratory of Bioelectronics, Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.
Jiang L; Collaborative Innovation Center of Tumor Marker Detection Technology, Equipment and Diagnosis-Therapy Integration in Universities of Shandong, Shandong Province Key Laboratory of Detection Technology for Tumor Makers, School of Chemistry and Chemical Engineering, Linyi University, Linyi 276005, China.
Liu Z; Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.
Liu S; State Key Laboratory of Bioelectronics, Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.
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Źródło :
Analytical chemistry [Anal Chem] 2021 Jun 08; Vol. 93 (22), pp. 7870-7878. Date of Electronic Publication: 2021 May 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Caspase 3*
Metal Nanoparticles*
Neoplasms*/diagnostic imaging
Neoplasms*/drug therapy
Photochemotherapy*
Reactive Oxygen Species*
Apoptosis ; Cell Line, Tumor ; Hep G2 Cells ; Humans ; Precision Medicine ; Silver ; Theranostic Nanomedicine
Czasopismo naukowe
Tytuł :
Overexpression of OsCASP1 Improves Calcium Tolerance in Rice.
Autorzy :
Wang Z; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Science and Technology, Guangxi University, Nanning 530004, China.
Chen Z; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Science and Technology, Guangxi University, Nanning 530004, China.
Zhang X; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Science and Technology, Guangxi University, Nanning 530004, China.
Wei Q; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Science and Technology, Guangxi University, Nanning 530004, China.
Xin Y; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Science and Technology, Guangxi University, Nanning 530004, China.
Zhang B; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Science and Technology, Guangxi University, Nanning 530004, China.
Liu F; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Science and Technology, Guangxi University, Nanning 530004, China.
Xia J; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Science and Technology, Guangxi University, Nanning 530004, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 01; Vol. 22 (11). Date of Electronic Publication: 2021 Jun 01.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium/*metabolism
Caspase 1/*genetics
Oryza/*genetics
Caspase 1/metabolism ; Cell Wall/genetics ; Gene Expression Regulation, Plant/genetics ; Oryza/growth & development ; Plant Roots/genetics ; Plant Roots/growth & development
Czasopismo naukowe
Tytuł :
The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation.
Autorzy :
Vijayaraj SL; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Feltham R; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Rashidi M; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Frank D; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Liu Z; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Simpson DS; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Ebert G; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Vince A; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Herold MJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Kueh A; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Pearson JS; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.; Department of Microbiology, Monash University, Clayton, VIC, Australia.; Department of Molecular and Translational Science, Monash University, Clayton, VIC, Australia.
Dagley LF; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Murphy JM; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Webb AI; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Lawlor KE; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia. .; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia. .; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia. .; Department of Molecular and Translational Science, Monash University, Clayton, VIC, Australia. .
Vince JE; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia. .; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia. .
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Źródło :
Nature communications [Nat Commun] 2021 May 11; Vol. 12 (1), pp. 2713. Date of Electronic Publication: 2021 May 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Processing, Post-Translational*
Caspase 1/*genetics
Inflammasomes/*genetics
Interleukin-1beta/*genetics
Proteasome Endopeptidase Complex/*genetics
Animals ; Caspase 1/immunology ; HEK293 Cells ; Humans ; Inflammasomes/immunology ; Inflammation ; Interleukin-1beta/immunology ; Lipopolysaccharides/administration & dosage ; Macrophages/immunology ; Macrophages/pathology ; Mice ; Mice, Knockout ; Primary Cell Culture ; Proteasome Endopeptidase Complex/immunology ; Proteolysis ; Reactive Oxygen Species/immunology ; Reactive Oxygen Species/metabolism ; Signal Transduction ; Ubiquitin/genetics ; Ubiquitin/immunology ; Ubiquitination
Czasopismo naukowe
Tytuł :
Effects of chitinase-3-like protein 1 on brain death-induced hepatocyte apoptosis via PAR2-JNK-caspase-3.
Autorzy :
Li ZX; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China; Henan Medical Engineering and Technology Center of Organ Transplantation, Zhengzhou, Henan, China; Zhengzhou Key Laboratory of Hepatobiliary & Pancreatic Diseases and Organ Transplantation, Zhengzhou, Henan, China; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan, China.
Yang DJ; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China; Henan Medical Engineering and Technology Center of Organ Transplantation, Zhengzhou, Henan, China; Zhengzhou Key Laboratory of Hepatobiliary & Pancreatic Diseases and Organ Transplantation, Zhengzhou, Henan, China.
Huo ZK; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China; Henan Medical Engineering and Technology Center of Organ Transplantation, Zhengzhou, Henan, China; Zhengzhou Key Laboratory of Hepatobiliary & Pancreatic Diseases and Organ Transplantation, Zhengzhou, Henan, China.
Wen PH; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China; Henan Medical Engineering and Technology Center of Organ Transplantation, Zhengzhou, Henan, China.
Hu BW; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China; Henan Medical Engineering and Technology Center of Organ Transplantation, Zhengzhou, Henan, China.
Wang ZH; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China; Henan Medical Engineering and Technology Center of Organ Transplantation, Zhengzhou, Henan, China.
Guo WZ; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China; Henan Medical Engineering and Technology Center of Organ Transplantation, Zhengzhou, Henan, China; Zhengzhou Key Laboratory of Hepatobiliary & Pancreatic Diseases and Organ Transplantation, Zhengzhou, Henan, China.
Zhang SJ; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China; Henan Medical Engineering and Technology Center of Organ Transplantation, Zhengzhou, Henan, China; Zhengzhou Key Laboratory of Hepatobiliary & Pancreatic Diseases and Organ Transplantation, Zhengzhou, Henan, China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 May 07; Vol. 552, pp. 150-156. Date of Electronic Publication: 2021 Mar 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*genetics
Brain Death/*physiopathology
Caspase 3/*genetics
Chitinase-3-Like Protein 1/*genetics
Hepatocytes/*metabolism
JNK Mitogen-Activated Protein Kinases/*genetics
Receptor, PAR-2/*genetics
Animals ; Apoptosis/drug effects ; Caspase 3/metabolism ; Cell Line, Tumor ; Cells, Cultured ; Chitin/pharmacology ; Chitinase-3-Like Protein 1/metabolism ; Gene Expression Regulation ; Hepatocytes/cytology ; Hepatocytes/drug effects ; Humans ; JNK Mitogen-Activated Protein Kinases/metabolism ; Male ; RNA Interference ; Rats, Sprague-Dawley ; Receptor, PAR-2/metabolism ; Signal Transduction/drug effects ; Signal Transduction/genetics ; THP-1 Cells
Czasopismo naukowe
Tytuł :
Cellular prion protein activates Caspase 3 for apoptotic defense mechanism in astrocytes.
Autorzy :
Marques CMS; Center for Natural Sciences and Humanities, Federal University of ABC (UFABC), Avenida dos Estados, 5001, Bl.B, Santo André, SP, 09210-580, Brazil.
Pedron T; Center for Natural Sciences and Humanities, Federal University of ABC (UFABC), Avenida dos Estados, 5001, Bl.B, Santo André, SP, 09210-580, Brazil.
Batista BL; Center for Natural Sciences and Humanities, Federal University of ABC (UFABC), Avenida dos Estados, 5001, Bl.B, Santo André, SP, 09210-580, Brazil.
Cerchiaro G; Center for Natural Sciences and Humanities, Federal University of ABC (UFABC), Avenida dos Estados, 5001, Bl.B, Santo André, SP, 09210-580, Brazil. .
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2021 May; Vol. 476 (5), pp. 2149-2158. Date of Electronic Publication: 2021 Feb 05.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Astrocytes/*metabolism
Caspase 3/*metabolism
PrPC Proteins/*metabolism
Animals ; Caspase 3/genetics ; Cell Line, Transformed ; Enzyme Activation ; Mice ; PrPC Proteins/genetics
Czasopismo naukowe
Tytuł :
Requirement for Serine-384 in Caspase-2 processing and activity.
Autorzy :
Zamaraev AV; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia, 119991.
Volik PI; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia, 119991.
Nilov DK; Belozersky Institute of Physicochemical Biology, MV Lomonosov Moscow State University, Moscow, Russia, 119991.
Turkina MV; Faculty of Medicine and Heath Sciences, Department of Clinical and Experimental Medicine, Linköping University, 58185, Linköping, Sweden.
Egorshina AY; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia, 119991.
Gorbunova AS; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia, 119991.
Iarovenko SI; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia, 119991.
Zhivotovsky B; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia, 119991.; Division of Toxicology, Institute of Environmental Medicine, Karolinska Institute, Box 210, 17177, Stockholm, Sweden.
Kopeina GS; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia, 119991. .
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Źródło :
Cell death & disease [Cell Death Dis] 2020 Oct 03; Vol. 11 (10), pp. 825. Date of Electronic Publication: 2020 Oct 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*genetics
Caspase 2/*genetics
Cysteine Endopeptidases/*genetics
Serine/*metabolism
Adenocarcinoma/genetics ; Binding Sites ; Caspase 2/metabolism ; Caspase 9/metabolism ; Cysteine Endopeptidases/metabolism ; Humans ; Mutation, Missense/genetics ; Serine/genetics
Czasopismo naukowe
Tytuł :
Chikusetsu saponin IVa alleviated sevoflurane-induced neuroinflammation and cognitive impairment by blocking NLRP3/caspase-1 pathway.
Autorzy :
Shao A; Department of Anesthesiology, Kunshan Traditional Chinese Medicine Hospital, Chaoyang Road 189, Kunshan, 510530, Jiangsu, China. .
Fei J; Department of Anesthesiology, Kunshan Traditional Chinese Medicine Hospital, Chaoyang Road 189, Kunshan, 510530, Jiangsu, China.
Feng S; Department of Anesthesiology, Kunshan Traditional Chinese Medicine Hospital, Chaoyang Road 189, Kunshan, 510530, Jiangsu, China.
Weng J; Department of Anesthesiology, Kunshan Traditional Chinese Medicine Hospital, Chaoyang Road 189, Kunshan, 510530, Jiangsu, China.
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Źródło :
Pharmacological reports : PR [Pharmacol Rep] 2020 Aug; Vol. 72 (4), pp. 833-845. Date of Electronic Publication: 2020 Mar 02.
Typ publikacji :
Journal Article
MeSH Terms :
Caspase Inhibitors/*therapeutic use
Cognitive Dysfunction/*drug therapy
Inflammation Mediators/*antagonists & inhibitors
NLR Family, Pyrin Domain-Containing 3 Protein/*antagonists & inhibitors
Oleanolic Acid/*analogs & derivatives
Saponins/*therapeutic use
Sevoflurane/*toxicity
Anesthetics, Inhalation/toxicity ; Animals ; Caspase 1/metabolism ; Caspase Inhibitors/pharmacology ; Cognitive Dysfunction/chemically induced ; Cognitive Dysfunction/metabolism ; Hippocampus/drug effects ; Hippocampus/metabolism ; Inflammation Mediators/metabolism ; Male ; Maze Learning/drug effects ; Maze Learning/physiology ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Oleanolic Acid/pharmacology ; Oleanolic Acid/therapeutic use ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Saponins/pharmacology
Czasopismo naukowe
Tytuł :
Caspase-8 mediates inflammation and disease in rodent malaria.
Autorzy :
Pereira LMN; Instituto Rene Rachou, FIOCRUZ-MG, Belo Horizonte, MG, 30190-002, Brazil.; Departamento de Bioquímica e Imunologia, ICB, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 31270-901, Brazil.; Department of Medicine, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
Assis PA; Department of Medicine, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
de Araújo NM; Instituto Rene Rachou, FIOCRUZ-MG, Belo Horizonte, MG, 30190-002, Brazil.; Departamento de Bioquímica e Imunologia, ICB, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 31270-901, Brazil.
Durso DF; Department of Medicine, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
Junqueira C; Instituto Rene Rachou, FIOCRUZ-MG, Belo Horizonte, MG, 30190-002, Brazil.
Ataíde MA; Instituto Rene Rachou, FIOCRUZ-MG, Belo Horizonte, MG, 30190-002, Brazil.; Departamento de Bioquímica e Imunologia, ICB, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 31270-901, Brazil.
Pereira DB; Centro de Pesquisas em Medicina Tropical, FIOCRUZ-RO, Porto Velho, RO, 76812-329, Brazil.
Lien E; Department of Medicine, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
Fitzgerald KA; Department of Medicine, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
Zamboni DS; Departamento de Biologia Celular Molecular e Bioagentes Patogenicos, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, 14049-900, Brazil.
Golenbock DT; Instituto Rene Rachou, FIOCRUZ-MG, Belo Horizonte, MG, 30190-002, Brazil.; Department of Medicine, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
Gazzinelli RT; Instituto Rene Rachou, FIOCRUZ-MG, Belo Horizonte, MG, 30190-002, Brazil. .; Departamento de Bioquímica e Imunologia, ICB, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 31270-901, Brazil. .; Department of Medicine, University of Massachusetts Medical School, Worcester, MA, 01605, USA. .; Plataforma de Medicina Translacional, Fundação Oswaldo Cruz/Faculdade de Medicina de Ribeirão Preto, Ribeirão Preto, SP, 14049-900, Brazil. .
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Źródło :
Nature communications [Nat Commun] 2020 Sep 14; Vol. 11 (1), pp. 4596. Date of Electronic Publication: 2020 Sep 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Caspase 8/*metabolism
Inflammation/*pathology
Malaria, Cerebral/*enzymology
Animals ; Brain/pathology ; Caspase 1/metabolism ; Dendritic Cells/metabolism ; Enzyme Activation ; Extracellular Matrix/metabolism ; Gene Expression Regulation ; Humans ; Interferon-gamma/metabolism ; Interleukin-1beta/metabolism ; Lipopolysaccharides ; Malaria, Cerebral/genetics ; Mice, Inbred C57BL ; Monocytes/metabolism ; Plasmodium chabaudi/physiology ; Spleen/metabolism ; Toll-Like Receptors/metabolism
Czasopismo naukowe
Tytuł :
Exoenzyme Y induces extracellular active caspase-7 accumulation independent from apoptosis: modulation of transmissible cytotoxicity.
Autorzy :
Renema P; Department of Physiology and Cell Biology, University of South Alabama, Mobile, Alabama.; Center for Lung Biology, University of South Alabama, Mobile, Alabama.
Kozhukhar N; Department of Physiology and Cell Biology, University of South Alabama, Mobile, Alabama.; Center for Lung Biology, University of South Alabama, Mobile, Alabama.
Pastukh V; Department of Physiology and Cell Biology, University of South Alabama, Mobile, Alabama.; Center for Lung Biology, University of South Alabama, Mobile, Alabama.
Spadafora D; Flow Cytometry Core, University of South Alabama, Mobile, Alabama.
Paudel SS; Department of Physiology and Cell Biology, University of South Alabama, Mobile, Alabama.; Center for Lung Biology, University of South Alabama, Mobile, Alabama.
Tambe DT; Department of Pharmacology, University of South Alabama, Mobile, Alabama.; Department of Mechanical Engineering, University of South Alabama, Mobile, Alabama.; Center for Lung Biology, University of South Alabama, Mobile, Alabama.
Alexeyev M; Department of Physiology and Cell Biology, University of South Alabama, Mobile, Alabama.; Center for Lung Biology, University of South Alabama, Mobile, Alabama.
Frank DW; Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, Milwaukee, Wisconsin.
Stevens T; Department of Physiology and Cell Biology, University of South Alabama, Mobile, Alabama.; Department of Internal Medicine, University of South Alabama, Mobile, Alabama.; Center for Lung Biology, University of South Alabama, Mobile, Alabama.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2020 Aug 01; Vol. 319 (2), pp. L380-L390. Date of Electronic Publication: 2020 Jun 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Apoptosis/*physiology
Bacterial Proteins/*metabolism
Caspase 7/*metabolism
Glucosyltransferases/*metabolism
Animals ; Caspase 3/metabolism ; Cell Death/physiology ; Cells, Cultured ; Endothelial Cells/metabolism ; Lung/metabolism ; Lung/microbiology ; Male ; Microvessels/metabolism ; Pseudomonas Infections/metabolism ; Pseudomonas aeruginosa/pathogenicity ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Edwardsiella piscicida type III protein EseJ suppresses apoptosis through down regulating type 1 fimbriae, which stimulate the cleavage of caspase-8.
Autorzy :
He TT; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.; University of Chinese Academy of Sciences, Beijing, China.
Zhou Y; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.; University of Chinese Academy of Sciences, Beijing, China.
Liu YL; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.; University of Chinese Academy of Sciences, Beijing, China.
Li DY; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.; University of Chinese Academy of Sciences, Beijing, China.
Nie P; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.; Laboratory for Marine Biology and Biotechnology, Pilot National Laboratory for Marine Science and Technology (Qingdao), Qingdao, China.; School of Marine Science and Engineering, Qingdao Agricultural University, Qingdao, China.
Li AH; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Xie HX; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
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Źródło :
Cellular microbiology [Cell Microbiol] 2020 Jul; Vol. 22 (7), pp. e13193. Date of Electronic Publication: 2020 Mar 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bacterial Proteins/*metabolism
Caspase 8/*metabolism
Edwardsiella/*metabolism
Fimbriae, Bacterial/*metabolism
Animals ; Apoptosis ; Caspase 3 ; Caspase 9 ; Cell Line ; Edwardsiella/pathogenicity ; Enterobacteriaceae Infections/metabolism ; Epitopes ; Fish Diseases/microbiology ; Host-Pathogen Interactions/physiology ; Larva ; Lipopolysaccharides ; Macrophages ; Mice ; Type III Secretion Systems/metabolism ; Zebrafish
SCR Organism :
Edwardsiella piscicida
Czasopismo naukowe
Tytuł :
Light activation of cyclometalated ruthenium complexes drives towards caspase 3 dependent apoptosis in gastric cancer cells.
Autorzy :
Solís-Ruiz JA; Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior s/n, Ciudad Universitaria, 04510 Ciudad de México, Mexico.
Barthe A; Strasbourg Université, Inserm UMR_S U1113, IRFAC, 3 Avenue Molière, 67200 Strasbourg, France.
Riegel G; Strasbourg Université, Inserm UMR_S U1113, IRFAC, 3 Avenue Molière, 67200 Strasbourg, France.
Saavedra-Díaz RO; Universidad Juárez Autónoma de Tabasco, División Académica de Ciencias Básicas, Carretera Cunduacán-Jalpa Km. 1, 86690 Cunduacán, Tabasco, Mexico.
Gaiddon C; Strasbourg Université, Inserm UMR_S U1113, IRFAC, 3 Avenue Molière, 67200 Strasbourg, France. Electronic address: .
Le Lagadec R; Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior s/n, Ciudad Universitaria, 04510 Ciudad de México, Mexico. Electronic address: .
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Źródło :
Journal of inorganic biochemistry [J Inorg Biochem] 2020 Jul; Vol. 208, pp. 111080. Date of Electronic Publication: 2020 Mar 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Caspase Inhibitors*/chemical synthesis
Caspase Inhibitors*/chemistry
Caspase Inhibitors*/pharmacology
Light*
Neoplasm Proteins*/antagonists & inhibitors
Neoplasm Proteins*/metabolism
Ruthenium*/chemistry
Ruthenium*/pharmacology
Stomach Neoplasms*/drug therapy
Stomach Neoplasms*/enzymology
Stomach Neoplasms*/pathology
Apoptosis/*drug effects
Caspase 3/*metabolism
Cell Line, Tumor ; Humans
Czasopismo naukowe

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