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Tytuł:
Biochemical profiling of the follicular environment to predict oocyte competence in cattle.
Autorzy:
Kussano NR; Institute of Biology, University of Brasilia, Brasília-DF, Brazil.
Franco MM; Laboratory of Animal Reproduction, Embrapa Genetic Resources and Biotechnology, Brasília-DF, Brazil.; School of Veterinary Medicine, Federal University of Uberlândia, Uberlândia, Minas Gerais, Brazil.; Institute of Biotechnology, Federal University of Uberlândia, Uberlândia, Minas Gerais, Brazil.
Dode MAN; Institute of Biology, University of Brasilia, Brasília-DF, Brazil.; Laboratory of Animal Reproduction, Embrapa Genetic Resources and Biotechnology, Brasília-DF, Brazil.
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Źródło:
PloS one [PLoS One] 2024 Mar 11; Vol. 19 (3), pp. e0298316. Date of Electronic Publication: 2024 Mar 11 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Progesterone*/metabolism
Cell-Free Nucleic Acids*/analysis
Female ; Cattle ; Animals ; Caspase 3/metabolism ; Serpin E2/metabolism ; Oocytes/metabolism ; Follicular Fluid/metabolism ; Estradiol/metabolism ; Cumulus Cells/metabolism
Czasopismo naukowe
Tytuł:
Epigallocatechin gallate improves neuronal damage in animal model of ischemic stroke and glutamate-exposed neurons via modulation of hippocalcin expression.
Autorzy:
Park DJ; Department of Anatomy, College of Veterinary Medicine, Research Institute of Life Science, Gyeongsang National University, Jinju, South Korea.
Kang JB; Department of Anatomy, College of Veterinary Medicine, Research Institute of Life Science, Gyeongsang National University, Jinju, South Korea.
Koh PO; Department of Anatomy, College of Veterinary Medicine, Research Institute of Life Science, Gyeongsang National University, Jinju, South Korea.
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Źródło:
PloS one [PLoS One] 2024 Mar 01; Vol. 19 (3), pp. e0299042. Date of Electronic Publication: 2024 Mar 01 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Catechin*/analogs & derivatives
Ischemic Stroke*/metabolism
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Animals ; Apoptosis ; Calcium/metabolism ; Caspase 3/metabolism ; Glutamic Acid/metabolism ; Hippocalcin/genetics ; Hippocalcin/metabolism ; Infarction, Middle Cerebral Artery/complications ; Infarction, Middle Cerebral Artery/drug therapy ; Neurons/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
A comparative study of apoptosis, pyroptosis, necroptosis, and PANoptosis components in mouse and human cells.
Autorzy:
Choudhury SM; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, United States of America.
Sarkar R; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, United States of America.
Karki R; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, United States of America.
Kanneganti TD; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Feb 27; Vol. 19 (2), pp. e0299577. Date of Electronic Publication: 2024 Feb 27 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Pyroptosis*
Necroptosis*
Humans ; Animals ; Mice ; Apoptosis ; Cell Death ; Caspase 1
Czasopismo naukowe
Tytuł:
Aerobic exercise protects MI heart through miR-133a-3p downregulation of connective tissue growth factor.
Autorzy:
Liu N; College of P.E, Beijing Normal University, Beijing, China.; School of Physical Education, Weinan Normal University, Weinan, Shaanxi, China.
Zhen Z; College of P.E, Beijing Normal University, Beijing, China.
Xiong X; College of P.E, Beijing Normal University, Beijing, China.
Xue Y; College of P.E, Beijing Normal University, Beijing, China.
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Źródło:
PloS one [PLoS One] 2024 Jan 25; Vol. 19 (1), pp. e0296430. Date of Electronic Publication: 2024 Jan 25 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs*/metabolism
Myocardial Infarction*/genetics
Myocardial Infarction*/therapy
Myocardial Infarction*/metabolism
Rats ; Male ; Mice ; Animals ; Caspase 3/metabolism ; Down-Regulation ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism ; Connective Tissue Growth Factor/genetics ; Connective Tissue Growth Factor/metabolism ; Hydrogen Peroxide/metabolism ; Myocytes, Cardiac/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Apoptosis/genetics
Czasopismo naukowe
Tytuł:
Evaluation of anticancer potential of tetracene-5,12-dione (A01) and pyrimidine-2,4-dione (A02) via caspase 3 and lactate dehydrogenase cytotoxicity investigations.
Autorzy:
Aziz M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Sarfraz M; College of Pharmacy, Al Ain University, Al Ain, United Arab Emirates.
Khurrum Ibrahim M; Baqai Medical University, Karachi, Pakistan.
Ejaz SA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Zehra T; Department of Basic Science & Humanities, Dawood University of Engineering & Technology, Karachi, Pakistan.
Ogaly HA; Chemistry Department, College of Science, King Khalid University, Abha, Saudi Arabia.
Arafat M; College of Pharmacy, Al Ain University, Al Ain, United Arab Emirates.
Al-Zahrani FAM; Chemistry Department, College of Science, King Khalid University, Abha, Saudi Arabia.
Li C; Department of Biology, Chemistry, Pharmacy, Free University of Berlin, Berlin, Germany.
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Źródło:
PloS one [PLoS One] 2023 Dec 21; Vol. 18 (12), pp. e0292455. Date of Electronic Publication: 2023 Dec 21 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Neoplasms*
Humans ; Caspase 3 ; Molecular Docking Simulation ; L-Lactate Dehydrogenase ; Pyrimidines/pharmacology ; DNA ; Structure-Activity Relationship ; Drug Screening Assays, Antitumor ; Molecular Structure
Czasopismo naukowe
Tytuł:
TNF licenses macrophages to undergo rapid caspase-1, -11, and -8-mediated cell death that restricts Legionella pneumophila infection.
Autorzy:
Pollock TY; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.
Vázquez Marrero VR; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.
Brodsky IE; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, United States of America.
Shin S; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 Jun 06; Vol. 19 (6), pp. e1010767. Date of Electronic Publication: 2023 Jun 06 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Legionnaires' Disease*
Pneumonia*/metabolism
Mice ; Animals ; Humans ; Caspase 1/metabolism ; Caspase 8/metabolism ; Inflammasomes ; Mice, Knockout ; Macrophages ; Caspases/metabolism ; Cell Death ; Tumor Necrosis Factor-alpha/metabolism ; Licensure
Czasopismo naukowe
Tytuł:
In vitro and in silico scolicidal effect of sanguinarine on the hydatid cyst protoscoleces.
Autorzy:
Hassanzadeh E; Cellular and Molecular Research Center, Cellular and Molecular Medicine Institute & Department of Medical Parasitology and Mycology, Urmia University of Medical Sciences, Urmia, Iran.
Khademvatan S; Cellular and Molecular Research Center, Cellular and Molecular Medicine Institute & Department of Medical Parasitology and Mycology, Urmia University of Medical Sciences, Urmia, Iran.
Jafari B; Department of Medicinal Chemistry, School of Pharmacy Urmia University of Medical Sciences, Urmia, Iran.
Jafari A; Cellular and Molecular Research Center, Cellular and Molecular Medicine Institute & Department of Medical Parasitology and Mycology, Urmia University of Medical Sciences, Urmia, Iran.
Yousefi E; Cellular and Molecular Research Center, Cellular and Molecular Medicine Institute & Department of Medical Parasitology and Mycology, Urmia University of Medical Sciences, Urmia, Iran.
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Źródło:
PloS one [PLoS One] 2023 Oct 25; Vol. 18 (10), pp. e0290947. Date of Electronic Publication: 2023 Oct 25 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Echinococcosis*/drug therapy
Echinococcus*
Echinococcus granulosus*
Animals ; Humans ; Acetylcholinesterase ; Caspase 3 ; Molecular Docking Simulation
Czasopismo naukowe
Tytuł:
Tumor suppressor p73 induces apoptosis of murine peritoneal cell after exposure to hydatid cyst antigens; a possibly survival mechanism of cystic echinococcosis in vivo mice model.
Autorzy:
Ahmadpour E; Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Spotin A; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Moghimi A; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Shahrivar F; Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Jadidi-Niaragh F; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Hajizadeh F; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Mehrani S; Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Mazhab-Jafari K; Department of Laboratory Sciences, Abadan University of Medical Sciences, Abadan, Iran.; Department of Parasitology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
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Źródło:
PloS one [PLoS One] 2023 Oct 05; Vol. 18 (10), pp. e0292434. Date of Electronic Publication: 2023 Oct 05 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Echinococcosis*
Echinococcus granulosus*
Tumor Protein p73*/metabolism
Animals ; Mice ; Caspase 3/metabolism ; Reactive Oxygen Species ; RNA, Messenger
Czasopismo naukowe
Tytuł:
Cardiopulmonary bypass in a rat model may shorten the lifespan of stored red blood cells by activating caspase-3.
Autorzy:
Han L; Department of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.; Department of Anesthesiology, KweiChow Moutai Hospital, Renhuai, Guizhou, China.
Li L; Department of Anesthesiology, Hospital of Banan District, Chongqing, China.
Linghu H; Department of Anesthesiology, Bishan Maternity and Child Hospital of Chongqing, Chongqing, China.
Zheng L; Department of Anesthesiology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Gou D; Department of Anesthesiology, KweiChow Moutai Hospital, Renhuai, Guizhou, China.
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Źródło:
PloS one [PLoS One] 2023 Sep 20; Vol. 18 (9), pp. e0290295. Date of Electronic Publication: 2023 Sep 20 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cardiopulmonary Bypass*
Longevity*
Animals ; Rats ; Adenosine Triphosphate ; Caspase 3 ; Erythrocytes ; Femoral Artery ; Fluorescein-5-isothiocyanate ; Phosphatidylserines
Czasopismo naukowe
Tytuł:
Controlling caspase activity in life and death.
Autorzy:
White K; Cutaneous Biology Research Center, Massachusetts General Hospital Research Institute/ Harvard Medical School, Boston, Massachusetts, United Sates of America.
Arama E; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Hardwick JM; Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2017 Feb 16; Vol. 13 (2), pp. e1006545. Date of Electronic Publication: 2017 Feb 16 (Print Publication: 2017).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Comment
MeSH Terms:
Caspase 3*
Caspases*
Apoptosis ; Caspase 8 ; Cell Death ; Enzyme Activation ; Humans
Czasopismo naukowe
Tytuł:
Growth arrest and DNA damage 45γ is required for caspase-dependent renal tubular cell apoptosis.
Autorzy:
Shin GT; Department of Nephrology, Ajou University School of Medicine, Suwon, Korea.
Lee HJ; Department of Nephrology, Ajou University School of Medicine, Suwon, Korea.
Park JE; Department of Nephrology, Ajou University School of Medicine, Suwon, Korea.
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Źródło:
PloS one [PLoS One] 2019 Feb 22; Vol. 14 (2), pp. e0212818. Date of Electronic Publication: 2019 Feb 22 (Print Publication: 2019).
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Caspase 3/*metabolism
Caspase 7/*metabolism
Epithelial Cells/*metabolism
Intracellular Signaling Peptides and Proteins/*metabolism
Kidney Tubules/*metabolism
Amino Acid Chloromethyl Ketones/pharmacology ; Caspase Inhibitors/pharmacology ; Cell Line ; Cisplatin/adverse effects ; Cisplatin/pharmacology ; Cyclohexylamines/pharmacology ; Cyclosporine/adverse effects ; Cyclosporine/pharmacology ; Epithelial Cells/pathology ; Humans ; Imidazoles/pharmacology ; Indoles/pharmacology ; Kidney Tubules/pathology ; Phenylenediamines/pharmacology ; GADD45 Proteins
Czasopismo naukowe
Tytuł:
The use of HRM shifts in qPCR to investigate a much neglected aspect of interference by intracellular nanoparticles.
Autorzy:
Sanabria NM; A Division of National Health Laboratory Services, National Institute for Occupational Health, Johannesburg, South Africa.
Gulumian M; A Division of National Health Laboratory Services, National Institute for Occupational Health, Johannesburg, South Africa.; Haematology and Molecular Medicine Department, School of Pathology, University of the Witwatersrand, Johannesburg, South Africa.; Water Research Group, Unit for Environmental Sciences and Management, North West University, Potchefstroom, South Africa.
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Źródło:
PloS one [PLoS One] 2021 Dec 07; Vol. 16 (12), pp. e0260207. Date of Electronic Publication: 2021 Dec 07 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Caspase 7/*genetics
Gold/*chemistry
Real-Time Polymerase Chain Reaction/*standards
Caspase 7/chemistry ; Cell Line ; Citric Acid ; Drug Stability ; Humans ; Metal Nanoparticles ; Reference Standards
Czasopismo naukowe
Tytuł:
Salmonella Enteritidis T1SS protein SiiD inhibits NLRP3 inflammasome activation via repressing the mtROS-ASC dependent pathway.
Autorzy:
Guo Y; Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Jiangsu, China.; Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality, Ministry of A griculture of China, Yangzhou University, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-product Safety of the Ministry of Education, Yangzhou University, Jiangsu, China.; School of Nursing School of Public Health, Yangzhou University, Jiangsu, China.
Gu D; Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Jiangsu, China.; Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality, Ministry of A griculture of China, Yangzhou University, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-product Safety of the Ministry of Education, Yangzhou University, Jiangsu, China.
Huang T; Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Jiangsu, China.; Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality, Ministry of A griculture of China, Yangzhou University, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-product Safety of the Ministry of Education, Yangzhou University, Jiangsu, China.
Li A; Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Jiangsu, China.; Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality, Ministry of A griculture of China, Yangzhou University, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-product Safety of the Ministry of Education, Yangzhou University, Jiangsu, China.
Zhou Y; Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Jiangsu, China.; Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality, Ministry of A griculture of China, Yangzhou University, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-product Safety of the Ministry of Education, Yangzhou University, Jiangsu, China.
Kang X; Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Jiangsu, China.; Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality, Ministry of A griculture of China, Yangzhou University, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-product Safety of the Ministry of Education, Yangzhou University, Jiangsu, China.
Meng C; Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Jiangsu, China.; Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality, Ministry of A griculture of China, Yangzhou University, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-product Safety of the Ministry of Education, Yangzhou University, Jiangsu, China.
Xiong D; Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Jiangsu, China.; Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality, Ministry of A griculture of China, Yangzhou University, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-product Safety of the Ministry of Education, Yangzhou University, Jiangsu, China.
Song L; Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Jiangsu, China.; Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality, Ministry of A griculture of China, Yangzhou University, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-product Safety of the Ministry of Education, Yangzhou University, Jiangsu, China.
Jiao X; Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Jiangsu, China.; Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality, Ministry of A griculture of China, Yangzhou University, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-product Safety of the Ministry of Education, Yangzhou University, Jiangsu, China.
Pan Z; Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Jiangsu, China.; Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality, Ministry of A griculture of China, Yangzhou University, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-product Safety of the Ministry of Education, Yangzhou University, Jiangsu, China.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 May 08; Vol. 19 (5), pp. e1011381. Date of Electronic Publication: 2023 May 08 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Inflammasomes*
NLR Family, Pyrin Domain-Containing 3 Protein*/genetics
NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism
Animals ; Mice ; Salmonella enteritidis ; Type I Secretion Systems ; Signal Transduction ; Caspase 1/metabolism ; Interleukin-1beta/metabolism
Czasopismo naukowe
Tytuł:
Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis.
Autorzy:
Wang X; Guangdong Key Laboratory of Pharmaceutical Functional Genes, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China.; Laboratory for Marine Biology and Biotechnology, Pilot National Laboratory for Marine Science and Technology, Qingdao, People's Republic of China.
Wei X; Guangdong Key Laboratory of Pharmaceutical Functional Genes, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China.; Laboratory for Marine Biology and Biotechnology, Pilot National Laboratory for Marine Science and Technology, Qingdao, People's Republic of China.
Lu Y; Guangdong Key Laboratory of Pharmaceutical Functional Genes, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China.
Wang Q; Guangdong Key Laboratory of Pharmaceutical Functional Genes, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China.
Fu R; Guangdong Key Laboratory of Pharmaceutical Functional Genes, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China.
Wang Y; Guangdong Key Laboratory of Pharmaceutical Functional Genes, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China.
Wang Q; Guangdong Key Laboratory of Pharmaceutical Functional Genes, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China.
Wang X; Guangdong Key Laboratory of Pharmaceutical Functional Genes, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China.
Chen S; Guangdong Key Laboratory of Pharmaceutical Functional Genes, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China.
Xu A; Guangdong Key Laboratory of Pharmaceutical Functional Genes, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China.; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, People's Republic of China.
Yuan S; Guangdong Key Laboratory of Pharmaceutical Functional Genes, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China.; Laboratory for Marine Biology and Biotechnology, Pilot National Laboratory for Marine Science and Technology, Qingdao, People's Republic of China.
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Źródło:
PLoS biology [PLoS Biol] 2023 May 03; Vol. 21 (5), pp. e3002062. Date of Electronic Publication: 2023 May 03 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Pyroptosis*/physiology
Lancelets*/genetics
Lancelets*/metabolism
Animals ; Cell Death ; Necrosis ; Caspase 3/metabolism
Czasopismo naukowe
Tytuł:
Expression levels of cleaved caspase-3 and caspase-3 in tumorigenesis and prognosis of oral tongue squamous cell carcinoma.
Autorzy:
Liu PF; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Hu YC; Department of Radiation Oncology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Kang BH; Department of Otorhinolaryngology-Head & Neck Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Department of Otorhinolaryngology, School of Medicine, National Defense Medical Center, Taipei, Taiwan.
Tseng YK; Department of Orthopedics, Show Chwan Memorial Hospital, Changhua, Taiwan.; Department of Orthopedics, National Cheng Kung University Hospital, Tainan, Taiwan.
Wu PC; Department of Nutrition, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Liang CC; Department of Nutrition, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Hou YY; Department of Otorhinolaryngology-Head & Neck Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Fu TY; Department of Pathology and Laboratory Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Liou HH; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Hsieh IC; Department of Pathology and Laboratory Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Ger LP; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan.
Shu CW; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
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Źródło:
PloS one [PLoS One] 2017 Jul 10; Vol. 12 (7), pp. e0180620. Date of Electronic Publication: 2017 Jul 10 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Carcinogenesis/*metabolism
Carcinoma, Squamous Cell/*enzymology
Carcinoma, Squamous Cell/*pathology
Caspase 3/*metabolism
Tongue Neoplasms/*enzymology
Tongue Neoplasms/*pathology
Adult ; Carcinogenesis/pathology ; Caspase 8/metabolism ; Caspase 9/metabolism ; Cell Differentiation ; Disease-Free Survival ; Female ; Humans ; Male ; Middle Aged ; Prognosis
Czasopismo naukowe
Tytuł:
Blocking Caspase-1/Gsdmd and Caspase-3/-8/Gsdme pyroptotic pathways rescues silicosis in mice.
Autorzy:
Kang L; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animals for Disease Study, Jiangsu Key Laboratory of Molecular Medicine, Model Animal Research Center, National Resource Center for Mutant Mice of China, Nanjing Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing, China.
Dai J; Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, Nanjing, China.
Wang Y; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animals for Disease Study, Jiangsu Key Laboratory of Molecular Medicine, Model Animal Research Center, National Resource Center for Mutant Mice of China, Nanjing Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing, China.
Shi P; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animals for Disease Study, Jiangsu Key Laboratory of Molecular Medicine, Model Animal Research Center, National Resource Center for Mutant Mice of China, Nanjing Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing, China.
Zou Y; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animals for Disease Study, Jiangsu Key Laboratory of Molecular Medicine, Model Animal Research Center, National Resource Center for Mutant Mice of China, Nanjing Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing, China.
Pei J; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animals for Disease Study, Jiangsu Key Laboratory of Molecular Medicine, Model Animal Research Center, National Resource Center for Mutant Mice of China, Nanjing Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing, China.
Tian Y; Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, Nanjing, China.
Zhang J; Jiangsu Key Laboratory of Organ Transplantation, Wuxi People's Hospital, Nanjing Medical University, Wuxi, China.
Buranasudja VC; Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.
Chen J; Jiangsu Key Laboratory of Organ Transplantation, Wuxi People's Hospital, Nanjing Medical University, Wuxi, China.
Cai H; Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, Nanjing, China.
Gao X; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animals for Disease Study, Jiangsu Key Laboratory of Molecular Medicine, Model Animal Research Center, National Resource Center for Mutant Mice of China, Nanjing Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing, China.
Lin Z; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animals for Disease Study, Jiangsu Key Laboratory of Molecular Medicine, Model Animal Research Center, National Resource Center for Mutant Mice of China, Nanjing Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing, China.
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Źródło:
PLoS genetics [PLoS Genet] 2022 Dec 02; Vol. 18 (12), pp. e1010515. Date of Electronic Publication: 2022 Dec 02 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Silicosis*/drug therapy
Silicosis*/genetics
Mice ; Animals ; Caspase 8 ; Caspase 1/genetics ; Caspase 3/genetics ; Pyroptosis/genetics
Czasopismo naukowe
Tytuł:
Intracellular cGMP increase is not involved in thyroid cancer cell death.
Autorzy:
Alessandro S; Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.; International PhD School in Clinical and Experimental Medicine (CEM), University of Modena and Reggio Emilia, Modena, Italy.
Paradiso E; Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Lazzaretti C; Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Sperduti S; Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.; Center for Genomic Research, University of Modena and Reggio Emilia, Modena, Italy.
Perri C; Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Antoniani F; Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Righi S; Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Simoni M; Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.; Center for Genomic Research, University of Modena and Reggio Emilia, Modena, Italy.; Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria di Modena, Modena, Italy.
Brigante G; Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.; Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria di Modena, Modena, Italy.
Casarini L; Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.; Center for Genomic Research, University of Modena and Reggio Emilia, Modena, Italy.
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Źródło:
PloS one [PLoS One] 2023 Mar 30; Vol. 18 (3), pp. e0283888. Date of Electronic Publication: 2023 Mar 30 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Piperazines*/pharmacology
Thyroid Neoplasms*
Male ; Humans ; Vardenafil Dihydrochloride/pharmacology ; Caspase 3 ; Sulfones/pharmacology ; Phosphodiesterase Inhibitors/pharmacology ; Cyclic GMP/metabolism ; Cell Death
Czasopismo naukowe
Tytuł:
Intestinal edema induced by LPS-induced endotoxemia is associated with an inflammasome adaptor ASC.
Autorzy:
Yamamoto T; Department of Pathology, Proteo-Science Center and Graduate School of Medicine, Ehime University, Toon, Ehime, Japan.
Kurata M; Department of Pathology, Proteo-Science Center and Graduate School of Medicine, Ehime University, Toon, Ehime, Japan.
Kaneko N; Department of Pathology, Proteo-Science Center and Graduate School of Medicine, Ehime University, Toon, Ehime, Japan.
Masumoto J; Department of Pathology, Proteo-Science Center and Graduate School of Medicine, Ehime University, Toon, Ehime, Japan.
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Źródło:
PloS one [PLoS One] 2023 Feb 17; Vol. 18 (2), pp. e0281746. Date of Electronic Publication: 2023 Feb 17 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Inflammasomes*/metabolism
Endotoxemia*/chemically induced
Animals ; Mice ; Lipopolysaccharides ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; CARD Signaling Adaptor Proteins/genetics ; CARD Signaling Adaptor Proteins/metabolism ; Mice, Inbred C57BL ; Caspase 1/metabolism ; Inflammation/metabolism ; Interleukin-1beta/metabolism ; Edema
Czasopismo naukowe
Tytuł:
Gasdermin-D and Caspase-7 are the key Caspase-1/8 substrates downstream of the NAIP5/NLRC4 inflammasome required for restriction of Legionella pneumophila.
Autorzy:
Gonçalves AV; Department of Cell Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Margolis SR; Division of Immunology and Pathogenesis, Department of Molecular and Cell Biology, and Cancer Research Laboratory, University of California, Berkeley, California, United States of America.
Quirino GFS; Department of Cell Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Mascarenhas DPA; Department of Cell Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Rauch I; Division of Immunology and Pathogenesis, Department of Molecular and Cell Biology, and Cancer Research Laboratory, University of California, Berkeley, California, United States of America.
Nichols RD; Division of Immunology and Pathogenesis, Department of Molecular and Cell Biology, and Cancer Research Laboratory, University of California, Berkeley, California, United States of America.
Ansaldo E; Division of Immunology and Pathogenesis, Department of Molecular and Cell Biology, and Cancer Research Laboratory, University of California, Berkeley, California, United States of America.
Fontana MF; Division of Immunology and Pathogenesis, Department of Molecular and Cell Biology, and Cancer Research Laboratory, University of California, Berkeley, California, United States of America.
Vance RE; Division of Immunology and Pathogenesis, Department of Molecular and Cell Biology, and Cancer Research Laboratory, University of California, Berkeley, California, United States of America.; Howard Hughes Medical Institute, University of California, Berkeley, California, United States of America.
Zamboni DS; Department of Cell Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
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Źródło:
PLoS pathogens [PLoS Pathog] 2019 Jun 28; Vol. 15 (6), pp. e1007886. Date of Electronic Publication: 2019 Jun 28 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis Regulatory Proteins/*immunology
Calcium-Binding Proteins/*immunology
Caspase 1/*immunology
Caspase 7/*immunology
Caspase 8/*immunology
Inflammasomes/*immunology
Legionella pneumophila/*immunology
Legionnaires' Disease/*immunology
Neuronal Apoptosis-Inhibitory Protein/*immunology
Animals ; Apoptosis Regulatory Proteins/genetics ; Calcium-Binding Proteins/genetics ; Caspase 1/genetics ; Caspase 7/genetics ; Caspase 8/genetics ; Inflammasomes/genetics ; Intracellular Signaling Peptides and Proteins ; Legionnaires' Disease/genetics ; Legionnaires' Disease/pathology ; Mice ; Mice, Knockout ; Neuronal Apoptosis-Inhibitory Protein/genetics ; Phosphate-Binding Proteins
Czasopismo naukowe
Tytuł:
Wharton jelly-derived mesenchymal stem cell exosomes induce apoptosis and suppress EMT signaling in cervical cancer cells as an effective drug carrier system of paclitaxel.
Autorzy:
Abas BI; Department of Medicinal Biochemistry, School of Medicine, Aydin Adnan Menderes University, Aydin, Turkey.
Demirbolat GM; Department of Pharmaceutical Technology, Faculty of Pharmacy, Acibadem University, Istanbul, Turkey.
Cevik O; Department of Medicinal Biochemistry, School of Medicine, Aydin Adnan Menderes University, Aydin, Turkey.
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Źródło:
PloS one [PLoS One] 2022 Sep 15; Vol. 17 (9), pp. e0274607. Date of Electronic Publication: 2022 Sep 15 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Exosomes*/metabolism
Mesenchymal Stem Cells*/metabolism
Uterine Cervical Neoplasms*/drug therapy
Uterine Cervical Neoplasms*/metabolism
Wharton Jelly*/metabolism
Apoptosis ; Caspase 3/metabolism ; Caspase 9/metabolism ; Drug Carriers/metabolism ; Epithelial-Mesenchymal Transition ; Female ; HeLa Cells ; Humans ; Paclitaxel/metabolism ; Paclitaxel/pharmacology ; Transforming Growth Factor beta/metabolism ; bcl-2-Associated X Protein/metabolism ; beta Catenin/metabolism
Czasopismo naukowe

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