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Tytuł:
In vivo imaging of cathepsin B in activated glia in the brain after orofacial formalin test.
Autorzy:
McIlwrath SL; New Mexico VA Health Care System, Albuquerque, NM, 87108, USA. .
Carroll-Portillo AC; New Mexico VA Health Care System, Albuquerque, NM, 87108, USA.; Division of Gastroenterology and Hepatology, University of New Mexico, Albuquerque, NM, 87131, USA.
Lin HC; New Mexico VA Health Care System, Albuquerque, NM, 87108, USA.; Division of Gastroenterology and Hepatology, University of New Mexico, Albuquerque, NM, 87131, USA.
Westlund KN; New Mexico VA Health Care System, Albuquerque, NM, 87108, USA.; Department of Anesthesiology and Critical Care Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM, 87106, USA.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 24; Vol. 14 (1), pp. 4517. Date of Electronic Publication: 2024 Feb 24.
Typ publikacji:
Journal Article
MeSH Terms:
Cathepsin B*/metabolism
Fluorescent Dyes*/metabolism
Rats ; Animals ; Pain Measurement ; Brain/diagnostic imaging ; Brain/metabolism ; Microglia/metabolism ; Facial Pain/metabolism ; Formaldehyde/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cathepsin B aggravates atherosclerosis in ApoE-deficient mice by modulating vascular smooth muscle cell pyroptosis through NF-κB / NLRP3 signaling pathway.
Autorzy:
Li H; Department of Cardiology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.; Institute of Medical Sciences, Guizhou Medical University, Guiyang, Guizhou, China.; School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou, China.
Zhao Q; Department of Cardiology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.; Institute of Medical Sciences, Guizhou Medical University, Guiyang, Guizhou, China.; School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou, China.
Liu D; Department of Cardiology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.; Institute of Medical Sciences, Guizhou Medical University, Guiyang, Guizhou, China.
Zhou B; Department of Cardiology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.; Institute of Medical Sciences, Guizhou Medical University, Guiyang, Guizhou, China.; School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou, China.
Liao F; Department of Cardiology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.; Institute of Medical Sciences, Guizhou Medical University, Guiyang, Guizhou, China.; School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou, China.
Chen L; Department of Cardiology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.; Institute of Medical Sciences, Guizhou Medical University, Guiyang, Guizhou, China.; School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou, China.
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Źródło:
PloS one [PLoS One] 2024 Jan 02; Vol. 19 (1), pp. e0294514. Date of Electronic Publication: 2024 Jan 02 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Atherosclerosis*/metabolism
Cathepsin B*/metabolism
Plaque, Atherosclerotic*/pathology
Animals ; Mice ; Inflammasomes/metabolism ; Mice, Knockout, ApoE ; Muscle, Smooth, Vascular/metabolism ; NF-kappa B/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Pyroptosis ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Human Mast Cells Upregulate Cathepsin B, a Novel Marker of Itch in Psoriasis.
Autorzy:
West PW; Lydia Becker Institute of Immunology and Inflammation, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK.
Tontini C; Lydia Becker Institute of Immunology and Inflammation, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK.
Atmoko H; Lydia Becker Institute of Immunology and Inflammation, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK.
Kiss O; Lydia Becker Institute of Immunology and Inflammation, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK.
Garner T; Division of Developmental Biology and Medicine, Manchester Institute for Collaborative Research on Ageing, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M23 9LT, UK.
Bahri R; Lydia Becker Institute of Immunology and Inflammation, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK.
Warren RB; Lydia Becker Institute of Immunology and Inflammation, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK.; Centre for Dermatology Research, The University of Manchester & Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M23 9LT, UK.; NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M23 9LT, UK.
Griffiths CEM; Lydia Becker Institute of Immunology and Inflammation, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK.; Centre for Dermatology Research, The University of Manchester & Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M23 9LT, UK.; NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M23 9LT, UK.
Stevens A; Division of Developmental Biology and Medicine, Manchester Institute for Collaborative Research on Ageing, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M23 9LT, UK.
Bulfone-Paus S; Lydia Becker Institute of Immunology and Inflammation, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK.; Centre for Dermatology Research, The University of Manchester & Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M23 9LT, UK.; NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M23 9LT, UK.
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Źródło:
Cells [Cells] 2023 Aug 30; Vol. 12 (17). Date of Electronic Publication: 2023 Aug 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cathepsin B*/genetics
Psoriasis*
Humans ; Mast Cells ; Pruritus ; Skin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Selection of an Amino Acid Site with One of the Fastest Cleavage Kinetics by the Endosomal Protease Cathepsin B for Potential Use in Drug Delivery Systems.
Autorzy:
Khramtsov YV; Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia. .
Georgiev GP; Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.
Sobolev AS; Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia. .; Moscow State University, Moscow, Russia. .
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Źródło:
Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2023 Apr; Vol. 509 (1), pp. 78-80. Date of Electronic Publication: 2023 Jun 20.
Typ publikacji:
Journal Article
MeSH Terms:
Cathepsin B*/chemistry
Cathepsin B*/metabolism
Amino Acids*/metabolism
Kinetics ; Peptides/chemistry ; Endosomes/metabolism ; Drug Delivery Systems
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Human β-Defensin 3 Inhibition of P. gingivalis LPS-Induced IL-1β Production by BV-2 Microglia through Suppression of Cathepsins B and L.
Autorzy:
Inoue E; Faculty of Pharmacy, Yasuda Women's University, Hiroshima 731-0153, Japan.
Minatozaki S; Faculty of Pharmacy, Yasuda Women's University, Hiroshima 731-0153, Japan.
Shimizu S; Faculty of Pharmacy, Yasuda Women's University, Hiroshima 731-0153, Japan.
Miyamoto S; Faculty of Pharmacy, Yasuda Women's University, Hiroshima 731-0153, Japan.
Jo M; Faculty of Pharmacy, Yasuda Women's University, Hiroshima 731-0153, Japan.
Ni J; Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
Tozaki-Saitoh H; Department of Pharmaceutical Sciences, School of Pharmacy at Fukuoka, International University of Health and Welfare, Okawa 831-8501, Japan.
Oda K; Department of Pharmacology, Faculty of Pharmacy, Yasuda Women's University, Yasuhigashi, Hiroshima 731-0153, Japan.
Nonaka S; Department of Pharmacology, Faculty of Pharmacy, Yasuda Women's University, Yasuhigashi, Hiroshima 731-0153, Japan.
Nakanishi H; Department of Pharmacology, Faculty of Pharmacy, Yasuda Women's University, Yasuhigashi, Hiroshima 731-0153, Japan.
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Źródło:
Cells [Cells] 2024 Feb 04; Vol. 13 (3). Date of Electronic Publication: 2024 Feb 04.
Typ publikacji:
Journal Article
MeSH Terms:
beta-Defensins*/metabolism
Microglia*/metabolism
Humans ; Cathepsin B/metabolism ; I-kappa B Kinase/metabolism ; Inflammasomes/metabolism ; Interleukin-1beta/metabolism ; Lipopolysaccharides ; NF-kappa B/metabolism ; NF-KappaB Inhibitor alpha/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Virulence Factors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The HN protein of Newcastle disease virus induces cell apoptosis through the induction of lysosomal membrane permeabilization.
Autorzy:
Chen, Yu (AUTHOR)
Zhu, Shanshan (AUTHOR)
Liao, Tianxing (AUTHOR)
Wang, Chunxuan (AUTHOR)
Han, Jiajun (AUTHOR)
Yang, Zhenyu (AUTHOR)
Lu, Xiaolong (AUTHOR)
Hu, Zenglei (AUTHOR)
Hu, Jiao (AUTHOR)
Wang, Xiaoquan (AUTHOR)
Gu, Min (AUTHOR)
Gao, Ruyi (AUTHOR)
Liu, Kaituo (AUTHOR)
Liu, Xiaowen (AUTHOR)
Ding, Chan (AUTHOR)
Hu, Shunlin (AUTHOR)
Liu, Xiufan (AUTHOR)
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Źródło:
PLoS Pathogens. 2/14/2024, Vol. 20 Issue 2, p1-31. 31p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cancer cell-specific and pro-apoptotic SMAC peptide-doxorubicin conjugated prodrug encapsulated aposomes for synergistic cancer immunotherapy.
Autorzy:
Kim J; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea.; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, 02841, Republic of Korea.
Shim MK; Medicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Moon Y; Medicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.; Department of Bioengineering, Korea University, Seoul, 02841, Republic of Korea.
Kim J; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea.; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, 02841, Republic of Korea.
Cho H; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea.
Yun WS; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea.; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, 02841, Republic of Korea.
Shim N; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea.
Seong JK; Department of Bioengineering, Korea University, Seoul, 02841, Republic of Korea.
Lee Y; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea.
Lim DK; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, 02841, Republic of Korea.
Kim K; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2024 Mar 13; Vol. 22 (1), pp. 109. Date of Electronic Publication: 2024 Mar 13.
Typ publikacji:
Journal Article
MeSH Terms:
Prodrugs*/pharmacology
Prodrugs*/chemistry
Neoplasms*/drug therapy
Multienzyme Complexes*
Oligopeptides*
Humans ; Cathepsin B ; Liposomes ; Doxorubicin/pharmacology ; Doxorubicin/chemistry ; Immunotherapy ; Peptides ; Polyethylene Glycols ; Cell Line, Tumor ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Impact of Enniatin B and Beauvericin on Lysosomal Cathepsin B Secretion and Apoptosis Induction.
Autorzy:
Aufy M; Department of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna, 1090 Vienna, Austria.
Abdelaziz RF; Department of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna, 1090 Vienna, Austria.
Hussein AM; Department of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna, 1090 Vienna, Austria.; Programme for Proteomics, Paracelsus Private Medical University, 5020 Salzburg, Austria.
Topcagic N; Department of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna, 1090 Vienna, Austria.
Shamroukh H; Department of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna, 1090 Vienna, Austria.
Abdel-Maksoud MA; Botany and Microbiology Department, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Salem TZ; Biomedical Sciences Program, University of Science and Technology, Zewail City of Science and Technology, Giza 12511, Egypt.
Studenik CR; Department of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna, 1090 Vienna, Austria.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 19; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
Cathepsin B*/metabolism
Cathepsin D*/metabolism
Cathepsin L/metabolism ; Cell Death ; Apoptosis ; Lysosomes/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Significance of Cathepsin B in Mediating Radiation Resistance in Colon Carcinoma Cell Line (Caco-2).
Autorzy:
Abdelaziz RF; Division of Pharmacology and Toxicology, Department of Pharmaceutical Sciences, University of Vienna, 1090 Vienna, Austria.; Division of Human Health, International Atomic Energy Agency, Wagramer Str. 5, 1400 Vienna, Austria.
Hussein AM; Division of Pharmacology and Toxicology, Department of Pharmaceutical Sciences, University of Vienna, 1090 Vienna, Austria.
Kotob MH; Division of Pharmacology and Toxicology, Department of Pharmaceutical Sciences, University of Vienna, 1090 Vienna, Austria.
Weiss C; Division of Pharmacology and Toxicology, Department of Pharmaceutical Sciences, University of Vienna, 1090 Vienna, Austria.
Chelminski K; Division of Human Health, International Atomic Energy Agency, Wagramer Str. 5, 1400 Vienna, Austria.
Studenik CR; Division of Pharmacology and Toxicology, Department of Pharmaceutical Sciences, University of Vienna, 1090 Vienna, Austria.
Aufy M; Division of Pharmacology and Toxicology, Department of Pharmaceutical Sciences, University of Vienna, 1090 Vienna, Austria.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 09; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 09.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma*
Colonic Neoplasms*/radiotherapy
Humans ; Apoptosis ; Caco-2 Cells ; Cathepsin B/metabolism ; Cell Line, Tumor ; Phosphatidylinositol 3-Kinases ; Radiation, Ionizing ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Spatiotemporal roles of AMPK in PARP-1- and autophagy-dependent retinal pigment epithelial cell death caused by UVA.
Autorzy:
Wu AY; Department of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Chemical Biology and Molecular Biophysics Program, Taiwan International Graduate Program, Academia Sinica, Taipei, Taiwan.
Sekar P; Department of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Graduate Institute of Medical Sciences, Taipei Medical University, Taipei, Taiwan.
Huang DY; Department of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Hsu SH; Department of Ophthalmology, Cardinal Tien Hospital, New Taipei City, Taiwan.
Chan CM; Department of Ophthalmology, Cardinal Tien Hospital, New Taipei City, Taiwan. .; School of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan. .
Lin WW; Department of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan. .; Chemical Biology and Molecular Biophysics Program, Taiwan International Graduate Program, Academia Sinica, Taipei, Taiwan. .; Graduate Institute of Medical Sciences, Taipei Medical University, Taipei, Taiwan. .
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Źródło:
Journal of biomedical science [J Biomed Sci] 2023 Nov 07; Vol. 30 (1), pp. 91. Date of Electronic Publication: 2023 Nov 07.
Typ publikacji:
Journal Article
MeSH Terms:
Autophagic Cell Death*
Humans ; AMP-Activated Protein Kinases/genetics ; AMP-Activated Protein Kinases/metabolism ; Autophagy ; Cathepsin B/metabolism ; Cathepsin B/pharmacology ; Epithelial Cells/metabolism ; ErbB Receptors ; Poly(ADP-ribose) Polymerase Inhibitors/metabolism ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A LRRK2/dLRRK-mediated lysosomal pathway that contributes to glial cell death and DA neuron survival.
Autorzy:
Wang L; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Wang H; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Yi S; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Zhang S; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Ho MS; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
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Źródło:
Traffic (Copenhagen, Denmark) [Traffic] 2022 Oct; Vol. 23 (10), pp. 506-520. Date of Electronic Publication: 2022 Sep 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cathepsin B*/genetics
Cathepsin B*/metabolism
Dopaminergic Neurons*/metabolism
Cell Death ; Leucine/genetics ; Leucine/metabolism ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/genetics ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/metabolism ; Lysosomes/metabolism ; Mutation ; Neuroglia/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Circ_0020014 mediates CTSB expression and participates in IL-1β-prompted chondrocyte injury via interacting with miR-24-3p.
Autorzy:
Zhang C; Department of Spinal Surgery, Liyang People's Hospital, Liyang, Jiangsu, China.
He W; Department of Osteoarthritis, Liyang People's Hospital, Liyang, 213300, Jiangsu, China. .
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Źródło:
Journal of orthopaedic surgery and research [J Orthop Surg Res] 2023 Nov 18; Vol. 18 (1), pp. 877. Date of Electronic Publication: 2023 Nov 18.
Typ publikacji:
Journal Article
MeSH Terms:
Chondrocytes*
MicroRNAs*/genetics
Humans ; Cathepsin B ; Interleukin-1beta/pharmacology ; Apoptosis/genetics ; Cytokines
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Solubility affects IL-1β-producing activity of the synthetic candidalysin peptide.
Autorzy:
Mori T; Department of Oral Microbiology, Division of Oral Infection Health Sciences, Asahi University School of Dentistry, Mizuho, Gifu, Japan.
Kataoka H; Department of Oral Microbiology, Division of Oral Infection Health Sciences, Asahi University School of Dentistry, Mizuho, Gifu, Japan.
Tanabe G; Department of Oral Microbiology, Division of Oral Infection Health Sciences, Asahi University School of Dentistry, Mizuho, Gifu, Japan.
Into T; Department of Oral Microbiology, Division of Oral Infection Health Sciences, Asahi University School of Dentistry, Mizuho, Gifu, Japan.
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Źródło:
PloS one [PLoS One] 2022 Aug 30; Vol. 17 (8), pp. e0273663. Date of Electronic Publication: 2022 Aug 30 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cathepsin B*/metabolism
NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism
Candida albicans/metabolism ; Fungal Proteins ; Inflammasomes/metabolism ; Interleukin-1beta/metabolism ; Solubility ; Water/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B.
Autorzy:
Wu Y; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK.
Mumford P; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK.
Noy S; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK.
Cleverley K; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK.
Mrzyglod A; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK.
Luo D; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK.
van Dalen F; Department of Medical BioSciences, Radboudumc, Geert Grooteplein Zuid 28, 6525 GA, Nijmegen, The Netherlands.; Institute for Chemical Immunology, Geert Grooteplein Zuid 28, 6525 GA, Nijmegen, The Netherlands.
Verdoes M; Department of Medical BioSciences, Radboudumc, Geert Grooteplein Zuid 28, 6525 GA, Nijmegen, The Netherlands.; Institute for Chemical Immunology, Geert Grooteplein Zuid 28, 6525 GA, Nijmegen, The Netherlands.
Fisher EMC; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK.
Wiseman FK; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Aug 14; Vol. 11 (1), pp. 132. Date of Electronic Publication: 2023 Aug 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Down Syndrome*/pathology
Alzheimer Disease*/pathology
Humans ; Mice ; Animals ; Cystatin B/genetics ; Cathepsin B ; Microglia/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Molecular mechanism of vimentin nuclear localization associated with the migration and invasion of daughter cells derived from polyploid giant cancer cells.
Autorzy:
Fan, Linlin (AUTHOR)
Zheng, Minying (AUTHOR)
Zhou, Xinyue (AUTHOR)
Yu, Yongjun (AUTHOR)
Ning, Yidi (AUTHOR)
Fu, Wenzheng (AUTHOR)
Xu, Jing (AUTHOR)
Zhang, Shiwu (AUTHOR)
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Źródło:
Journal of Translational Medicine. 10/13/2023, Vol. 21 Issue 1, p1-18. 18p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cathepsin B p.Gly284Val Variant in Parkinson's Disease Pathogenesis.
Autorzy:
Milanowski LM; Department of Neurology, Mayo Clinic Florida, Jacksonville, FL 32224, USA.; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL 32224, USA.; Department of Neurology, Faculty of Health Science, Medical University of Warsaw, 02-091 Warsaw, Poland.
Hou X; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Bredenberg JM; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Fiesel FC; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL 32224, USA.; Neuroscience PhD Program, Mayo Graduate School, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Cocker LT; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Soto-Beasley AI; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Walton RL; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Strongosky AJ; Department of Neurology, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Faroqi AH; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL 32224, USA.; Neuroscience PhD Program, Mayo Graduate School, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Barcikowska M; Clinical Department of Neurology, Extrapyramidal Disorders and Alzheimer's Outpatient Clinic, Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw, 02-507 Warsaw, Poland.
Boczarska-Jedynak M; Department of Neurology and Restorative Medicine, Health Institute dr Boczarska-Jedynak, 32-600 Oswiecim, Poland.
Dulski J; Department of Neurology, Mayo Clinic Florida, Jacksonville, FL 32224, USA.; Department of Neurology, St. Adalbert Hospital, Copernicus PL Ltd., 80-462 Gdansk, Poland.; Division of Neurological and Psychiatric Nursing, Faculty of Health Sciences, Medical University of Gdansk, 80-210 Gdansk, Poland.
Fedoryshyn L; Lviv Regional Clinical Hospital, 79010 Lviv, Ukraine.
Janik P; Department of Neurology, Faculty of Health Science, Medical University of Warsaw, 02-091 Warsaw, Poland.
Potulska-Chromik A; Department of Neurology, Faculty of Health Science, Medical University of Warsaw, 02-091 Warsaw, Poland.
Karpinsky K; Uzhhorod Regional Clinical Centre of Neurosurgery and Neurology, 88018 Uzhhorod, Ukraine.
Krygowska-Wajs A; Department of Neurology, Jagiellonian University Medical College, 31-008 Krakow, Poland.
Lynch T; The Dublin Neurological Institute, Mater Misericordiae University Hospital, D07 W7XF Dublin, Ireland.; School of Medicine and Medical Science, University College Dublin, D04 V1W8 Dublin, Ireland.
Olszewska DA; The Dublin Neurological Institute, Mater Misericordiae University Hospital, D07 W7XF Dublin, Ireland.; School of Medicine and Medical Science, University College Dublin, D04 V1W8 Dublin, Ireland.; Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, Toronto, ON M5T 2S8, Canada.
Opala G; Department of Neurology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-055 Katowice, Poland.
Pulyk A; Uzhhorod National University, 88-000 Uzhhorod, Ukraine.
Rektorova I; Applied Neuroscience Research Group, Central European Institute of Technology, CEITEC MU, Masaryk University, 601-77 Brno, Czech Republic.; St. Anne's University Hospital and Faculty of Medicine, Masaryk University, 601-77 Brno, Czech Republic.
Sanotsky Y; Lviv Regional Clinical Hospital, 79010 Lviv, Ukraine.
Siuda J; Department of Neurology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-055 Katowice, Poland.
Widlak M; Bielanski Hospital, 01-809 Warsaw, Poland.
Slawek J; Department of Neurology, St. Adalbert Hospital, Copernicus PL Ltd., 80-462 Gdansk, Poland.; Division of Neurological and Psychiatric Nursing, Faculty of Health Sciences, Medical University of Gdansk, 80-210 Gdansk, Poland.
Rudzinska-Bar M; Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Krakow University, 30-705 Cracow, Poland.
Uitti R; Department of Neurology, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Figura M; Department of Neurology, Faculty of Health Science, Medical University of Warsaw, 02-091 Warsaw, Poland.
Szlufik S; Department of Neurology, Faculty of Health Science, Medical University of Warsaw, 02-091 Warsaw, Poland.
Rzonca-Niewczas S; Department of Medical Genetics, Institute of Mother and Child, 01-211 Warsaw, Poland.
Podgorska E; Institute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, 00-927 Warsaw, Poland.
McLean PJ; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL 32224, USA.; Neuroscience PhD Program, Mayo Graduate School, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Koziorowski D; Department of Neurology, Faculty of Health Science, Medical University of Warsaw, 02-091 Warsaw, Poland.
Ross OA; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL 32224, USA.; Neuroscience PhD Program, Mayo Graduate School, Mayo Clinic Florida, Jacksonville, FL 32224, USA.; School of Medicine and Medical Science, University College Dublin, D04 V1W8 Dublin, Ireland.; Department of Clinical Genomics, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Hoffman-Zacharska D; Department of Medical Genetics, Institute of Mother and Child, 01-211 Warsaw, Poland.; Institute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, 00-927 Warsaw, Poland.
Springer W; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL 32224, USA.; Neuroscience PhD Program, Mayo Graduate School, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Wszolek ZK; Department of Neurology, Mayo Clinic Florida, Jacksonville, FL 32224, USA.; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jun 25; Vol. 23 (13). Date of Electronic Publication: 2022 Jun 25.
Typ publikacji:
Journal Article
MeSH Terms:
Parkinson Disease*/genetics
Cathepsin B/*metabolism
Cathepsin B/genetics ; Genotype ; Heterozygote ; Humans ; Penetrance
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In Silico, In Vitro, and Clinical Investigations of Cathepsin B and Stefin A mRNA Expression and a Correlation Analysis in Kidney Cancer.
Autorzy:
Rudzinska-Radecka M; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Institute of Physical Chemistry, Polish Academy of Sciences, 01-224 Warsaw, Poland.
Frolova AS; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Department of Biotechnology, Sirius University of Science and Technology, 1 Olympic Ave., 354340 Sochi, Russia.
Balakireva AV; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, 117997 Moscow, Russia.
Gorokhovets NV; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Pokrovsky VS; Department of Biotechnology, Sirius University of Science and Technology, 1 Olympic Ave., 354340 Sochi, Russia.; Laboratory of Combined Treatment, N.N. Blokhin Cancer Research Center, 115478 Moscow, Russia.; Department of Biochemistry, Peoples' Friendship University of Russia (RUDN University), 117198 Moscow, Russia.
Sokolova DV; Department of Biotechnology, Sirius University of Science and Technology, 1 Olympic Ave., 354340 Sochi, Russia.; Laboratory of Combined Treatment, N.N. Blokhin Cancer Research Center, 115478 Moscow, Russia.; Department of Biochemistry, Peoples' Friendship University of Russia (RUDN University), 117198 Moscow, Russia.
Korolev DO; Institute for Urology and Reproductive Health, Sechenov University, 119992 Moscow, Russia.
Potoldykova NV; Institute for Urology and Reproductive Health, Sechenov University, 119992 Moscow, Russia.
Vinarov AZ; Institute for Urology and Reproductive Health, Sechenov University, 119992 Moscow, Russia.
Parodi A; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Department of Biotechnology, Sirius University of Science and Technology, 1 Olympic Ave., 354340 Sochi, Russia.
Zamyatnin AA Jr; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Department of Biotechnology, Sirius University of Science and Technology, 1 Olympic Ave., 354340 Sochi, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; Department of Immunology, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK.
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Źródło:
Cells [Cells] 2022 Apr 25; Vol. 11 (9). Date of Electronic Publication: 2022 Apr 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Renal Cell*/genetics
Cystatins*/metabolism
Kidney Neoplasms*/genetics
Cathepsin B/*metabolism
Cystatin A/*metabolism
Cathepsin B/genetics ; Cystatin A/genetics ; Female ; Humans ; Male ; RNA, Messenger/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 6394

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