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Wyszukujesz frazę ""ccr4"" wg kryterium: Temat


Tytuł:
Evaluation of Novel Targets, Including CC-Chemokine Receptor 4, in Adult T-Cell Acute Lymphoblastic Leukemia/Lymphoma: A Mayo Clinic Clinical and Pathologic Study.
Autorzy:
Khurana S; From the Division of Hematology/Oncology, University of Arizona Cancer Center, Tucson (Khurana).
Heckman MG; the Departments of Biomedical Statistics and Informatics (Heckman, Cochuyt) and Laboratory Medicine and Pathology (Jiang), and the Division of Hematology and Medical Oncology (Foran), Mayo Clinic Florida, Jacksonville.
Craig FE; the Divisions of Hematopathology (Craig) and Hematology and Medical Oncology (Sproat), Mayo Clinic Arizona, Phoenix.
Cochuyt JJ; the Departments of Biomedical Statistics and Informatics (Heckman, Cochuyt) and Laboratory Medicine and Pathology (Jiang), and the Division of Hematology and Medical Oncology (Foran), Mayo Clinic Florida, Jacksonville.
Greipp P; the Divisions of Laboratory Genetics (Greipp) and Hematology (Litzow), Mayo Clinic, Rochester, Minnesota.
Rahman ZA; the Division of Hematology and Medical Oncology, Sanford Roger Maris Cancer Center, Fargo, North Dakota (Rahman).
Sproat LZ; the Divisions of Hematopathology (Craig) and Hematology and Medical Oncology (Sproat), Mayo Clinic Arizona, Phoenix.
Litzow M; the Divisions of Laboratory Genetics (Greipp) and Hematology (Litzow), Mayo Clinic, Rochester, Minnesota.
Foran JM; the Departments of Biomedical Statistics and Informatics (Heckman, Cochuyt) and Laboratory Medicine and Pathology (Jiang), and the Division of Hematology and Medical Oncology (Foran), Mayo Clinic Florida, Jacksonville.
Jiang LJ; the Departments of Biomedical Statistics and Informatics (Heckman, Cochuyt) and Laboratory Medicine and Pathology (Jiang), and the Division of Hematology and Medical Oncology (Foran), Mayo Clinic Florida, Jacksonville.
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Źródło:
Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2024 Apr 01; Vol. 148 (4), pp. 471-475.
Typ publikacji:
Journal Article
MeSH Terms:
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/diagnosis
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/pathology
Lymphoma*
Precursor Cell Lymphoblastic Leukemia-Lymphoma*/diagnosis
Precursor Cell Lymphoblastic Leukemia-Lymphoma*/pathology
Lymphoma, B-Cell*
Adult ; Humans ; CD47 Antigen ; Receptors, CCR4 ; Interleukin-3 Receptor alpha Subunit ; T-Lymphocytes/pathology ; Proto-Oncogene Proteins c-bcl-2
Czasopismo naukowe
Tytuł:
CC Chemokine Receptor 4 (CCR4) as a Possible New Target for Therapy.
Autorzy:
Bogacka J; Department of Pain Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, 31-343 Krakow, Poland.
Pawlik K; Department of Pain Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, 31-343 Krakow, Poland.
Ciapała K; Department of Pain Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, 31-343 Krakow, Poland.
Ciechanowska A; Department of Pain Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, 31-343 Krakow, Poland.
Mika J; Department of Pain Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, 31-343 Krakow, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 09; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Receptors, CCR4*
Multiple Sclerosis*
Humans ; Chemokines
Czasopismo naukowe
Tytuł:
CCL17-CCR4 axis contributes to the onset of vitiligo in mice.
Autorzy:
Li H; Department of Dermatology, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huai'an, China.
Wang C; Department of Pharmacy, Eye Ear Nose & Throat Hospital, Fudan University, Shanghai, China.
Li X; Department of Dermatology, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huai'an, China.
Kong Y; Department of Dermatology, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huai'an, China.
Sun W; Department of Dermatology, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huai'an, China.
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Źródło:
Immunity, inflammation and disease [Immun Inflamm Dis] 2021 Sep; Vol. 9 (3), pp. 702-709. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, CCR4*
Vitiligo*
Animals ; Chemokine CCL17 ; Humans ; Ligands ; Mice ; Skin
Czasopismo naukowe
Tytuł:
Structure and assembly of the NOT10:11 module of the CCR4-NOT complex.
Autorzy:
Levdansky Y; RNA Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA.
Raisch T; Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, Germany. .
Deme JC; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA.
Pekovic F; RNA Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA.
Elmlund H; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA.
Lea SM; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA.
Valkov E; RNA Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA. .; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA. .
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Źródło:
Communications biology [Commun Biol] 2023 Jul 17; Vol. 6 (1), pp. 739. Date of Electronic Publication: 2023 Jul 17.
Typ publikacji:
Journal Article
MeSH Terms:
Ribonucleases*/chemistry
Transcription Factors*/metabolism
Humans ; Protein Binding ; Receptors, CCR4/metabolism
Czasopismo naukowe
Tytuł:
Systematic Assessment of Chemokine Signaling at Chemokine Receptors CCR4, CCR7 and CCR10.
Autorzy:
Lim HD; Infection and Immunity Program, Monash Biomedicine Discovery Institute, Clayton, VIC 3800, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.
Lane JR; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, Queen's Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK.; Centre of Membrane Protein and Receptors, Universities of Birmingham and Nottingham, Nottingham NG7 2UH, UK.
Canals M; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, Queen's Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK.; Centre of Membrane Protein and Receptors, Universities of Birmingham and Nottingham, Nottingham NG7 2UH, UK.
Stone MJ; Infection and Immunity Program, Monash Biomedicine Discovery Institute, Clayton, VIC 3800, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 19; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 19.
Typ publikacji:
Journal Article
MeSH Terms:
Chemokines/*metabolism
Receptors, CCR10/*metabolism
Receptors, CCR4/*metabolism
Receptors, CCR7/*metabolism
Enzyme-Linked Immunosorbent Assay ; Humans ; Receptors, CCR/genetics ; Receptors, CCR/metabolism ; Receptors, CCR10/genetics ; Receptors, CCR4/genetics ; Receptors, CCR7/genetics ; Signal Transduction/genetics ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł:
Efficient Redirection of NK Cells by Genetic Modification with Chemokine Receptors CCR4 and CCR2B.
Autorzy:
Feigl FF; Fraunhofer Institute for Cell Therapy and Immunology (IZI), 04103 Leipzig, Germany.
Stahringer A; Fraunhofer Institute for Cell Therapy and Immunology (IZI), 04103 Leipzig, Germany.
Peindl M; Chair of Tissue Engineering and Regenerative Medicine (TERM), University Hospital of Würzburg, 97070 Würzburg, Germany.
Dandekar G; Chair of Tissue Engineering and Regenerative Medicine (TERM), University Hospital of Würzburg, 97070 Würzburg, Germany.; Translational Center Regenerative Therapies, Fraunhofer Institute for Silicate Research (ISC), 97070 Würzburg, Germany.
Koehl U; Fraunhofer Institute for Cell Therapy and Immunology (IZI), 04103 Leipzig, Germany.; Institute for Clinical Immunology, University of Leipzig, 04103 Leipzig, Germany.
Fricke S; Fraunhofer Institute for Cell Therapy and Immunology (IZI), 04103 Leipzig, Germany.
Schmiedel D; Fraunhofer Institute for Cell Therapy and Immunology (IZI), 04103 Leipzig, Germany.; Institute for Clinical Immunology, University of Leipzig, 04103 Leipzig, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 04; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 04.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasms*/pathology
Receptors, Chimeric Antigen*/metabolism
Humans ; Immunotherapy, Adoptive ; Killer Cells, Natural ; Receptors, Antigen, T-Cell/metabolism ; Receptors, CCR4/metabolism ; Receptors, Chemokine/metabolism ; Receptors, CCR2
Czasopismo naukowe
Tytuł:
MiRNA-6089 inhibits rheumatoid arthritis fibroblast-like synoviocytes proliferation and induces apoptosis by targeting CCR4.
Autorzy:
Lin S; Department of Rheumatology, The Third Clinical College of Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, China.
Wang S; Department of Rheumatology, The Third Clinical College of Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, China.
Zhang Z; Department of Rheumatology, The Third Clinical College of Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, China.
Lu Y; Department of Rheumatology, The Third Clinical College of Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, China.
Yang M; Department of Rheumatology, The Third Clinical College of Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, China.
Chen P; Department of Rheumatology, The Third Clinical College of Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, China.
Chen L; Department of Pharmacy, The Third Clinical College of Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, China.
Wang M; Department of Nephrology, The Third Clinical College of Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, China.
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Źródło:
Archives of physiology and biochemistry [Arch Physiol Biochem] 2022 Dec; Vol. 128 (6), pp. 1426-1433. Date of Electronic Publication: 2020 Jun 17.
Typ publikacji:
Journal Article
MeSH Terms:
Synoviocytes*/metabolism
Synoviocytes*/pathology
MicroRNAs*/genetics
MicroRNAs*/metabolism
Arthritis, Rheumatoid*/genetics
Arthritis, Rheumatoid*/metabolism
Humans ; Caspase 3/genetics ; Caspase 3/metabolism ; Cell Proliferation ; Apoptosis/genetics ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Cells, Cultured ; Receptors, CCR4/metabolism
Czasopismo naukowe
Tytuł:
N-terminal Ago-binding domain of GW182 contains a tryptophan-rich region that confer binding to the CCR4-NOT complex.
Autorzy:
Wakiyama M; RIKEN Systems and Structural Biology Center, Riken Yokohama Institute, Yokohama, Japan.; Post-transcriptional Control Research Unit, RIKEN Center for Life Science Technologies, Yokohama, Japan.; Laboratory for Nonnatural Amino Acid Technology, RIKEN Center for Biosystems Dynamics Research, Yokohama, Japan.
Takimoto K; RIKEN Systems and Structural Biology Center, Riken Yokohama Institute, Yokohama, Japan.
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Źródło:
Genes to cells : devoted to molecular & cellular mechanisms [Genes Cells] 2022 Sep; Vol. 27 (9), pp. 579-585. Date of Electronic Publication: 2022 Jul 24.
Typ publikacji:
Journal Article
MeSH Terms:
Argonaute Proteins*/genetics
Argonaute Proteins*/metabolism
Autoantigens*/chemistry
Autoantigens*/genetics
Autoantigens*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
RNA-Binding Proteins*/genetics
RNA-Binding Proteins*/metabolism
Binding Sites ; Humans ; Protein Binding ; Receptors, CCR4/genetics ; Receptors, CCR4/metabolism ; Transcription Factors/metabolism ; Tryptophan/genetics ; Tryptophan/metabolism
Czasopismo naukowe
Tytuł:
The C-C Chemokines CCL17 and CCL22 and Their Receptor CCR4 in CNS Autoimmunity.
Autorzy:
Scheu S; Institute of Medical Microbiology and Hospital Hygiene, University of Düsseldorf, 40225 Düsseldorf, Germany. .
Ali S; Institute of Medical Microbiology and Hospital Hygiene, University of Düsseldorf, 40225 Düsseldorf, Germany. .
Ruland C; Department of Psychiatry, University of Münster, 48149 Münster, Germany. .; Cells in Motion, Cluster of Excellence, University of Münster, 48149 Münster, Germany. .
Arolt V; Department of Psychiatry, University of Münster, 48149 Münster, Germany. .
Alferink J; Department of Psychiatry, University of Münster, 48149 Münster, Germany. .; Cells in Motion, Cluster of Excellence, University of Münster, 48149 Münster, Germany. .; Department of Psychiatry, Alexian Brothers Hospital, 48149 Münster, Germany. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2017 Nov 02; Vol. 18 (11). Date of Electronic Publication: 2017 Nov 02.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Autoimmunity*/immunology
Autoimmune Diseases of the Nervous System/*immunology
Chemokine CCL17/*immunology
Chemokine CCL22/*immunology
Receptors, CCR4/*immunology
Animals ; Autoimmune Diseases of the Nervous System/drug therapy ; Autoimmune Diseases of the Nervous System/pathology ; Central Nervous System/drug effects ; Central Nervous System/immunology ; Central Nervous System/pathology ; Chemokine CCL17/analysis ; Chemokine CCL22/analysis ; Dendritic Cells/drug effects ; Dendritic Cells/immunology ; Dendritic Cells/pathology ; Encephalomyelitis, Autoimmune, Experimental/drug therapy ; Encephalomyelitis, Autoimmune, Experimental/immunology ; Encephalomyelitis, Autoimmune, Experimental/pathology ; Humans ; Molecular Targeted Therapy/methods ; Multiple Sclerosis/drug therapy ; Multiple Sclerosis/immunology ; Multiple Sclerosis/pathology ; Receptors, CCR4/analysis
Czasopismo naukowe
Tytuł:
HIV co-receptor-tropism: cellular and molecular events behind the enigmatic co-receptor switching.
Autorzy:
Yandrapally S; Department of Biochemistry, University of Hyderabad, Hyderabad, India.
Mohareer K; Department of Biochemistry, University of Hyderabad, Hyderabad, India.
Arekuti G; Department of Biochemistry, University of Hyderabad, Hyderabad, India.
Vadankula GR; Department of Biochemistry, University of Hyderabad, Hyderabad, India.
Banerjee S; Department of Biochemistry, University of Hyderabad, Hyderabad, India.
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Źródło:
Critical reviews in microbiology [Crit Rev Microbiol] 2021 Aug; Vol. 47 (4), pp. 499-516. Date of Electronic Publication: 2021 Apr 26.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Viral Tropism*
HIV Infections/*metabolism
HIV Infections/*virology
HIV-1/*physiology
Receptors, Virus/*metabolism
Animals ; HIV Infections/genetics ; HIV-1/genetics ; Humans ; Receptors, CCR4/genetics ; Receptors, CCR4/metabolism ; Receptors, CCR5/genetics ; Receptors, CCR5/metabolism ; Receptors, Virus/genetics ; Virus Internalization
Czasopismo naukowe
Tytuł:
IL-6 alters migration capacity of CD4 regulatory T cells in systemic lupus erythematosus.
Autorzy:
He S; Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xue M; Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Cai G; Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Źródło:
Scandinavian journal of immunology [Scand J Immunol] 2021 Nov; Vol. 94 (5), pp. e13099. Date of Electronic Publication: 2021 Sep 08.
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes/*immunology
Interleukin-6/*metabolism
Lupus Erythematosus, Systemic/*immunology
T-Lymphocytes, Regulatory/*immunology
Adult ; Aged ; Cell Movement ; Cells, Cultured ; Female ; Flow Cytometry ; Forkhead Transcription Factors/metabolism ; Humans ; Interleukin-10/metabolism ; Male ; Middle Aged ; Receptors, CCR4/metabolism ; Receptors, CCR6/metabolism
Czasopismo naukowe
Tytuł:
Small Molecule CCR4 Antagonists Protect Mice from Aspergillus Infection and Allergy.
Autorzy:
Bozza S; Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
Iannitti RG; Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
Pariano M; Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
Renga G; Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
Costantini C; Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
Romani L; Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
Bayry J; Institut National de la Santé et de la Recherche Médicale Centre de Recherche des Cordeliers Sorbonne Université, Université de Paris, 75006 Paris, France.; Indian Institute of Technology Palakkad, Palakkad 678557, India.
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Źródło:
Biomolecules [Biomolecules] 2021 Feb 25; Vol. 11 (3). Date of Electronic Publication: 2021 Feb 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aspergillosis/*drug therapy
Aspergillosis/*immunology
Aspergillosis, Allergic Bronchopulmonary/*drug therapy
Aspergillosis, Allergic Bronchopulmonary/*immunology
Aspergillus fumigatus/*immunology
Aspergillus fumigatus/*pathogenicity
Receptors, CCR4/*antagonists & inhibitors
Receptors, CCR4/*metabolism
Animals ; Aspergillosis/prevention & control ; Aspergillosis, Allergic Bronchopulmonary/prevention & control ; Cystic Fibrosis/drug therapy ; Enzyme-Linked Immunosorbent Assay ; Fluorescent Antibody Technique ; Mice ; Mice, Inbred C57BL ; Vaccination
Czasopismo naukowe
Tytuł:
What does elevated TARC/CCL17 expression tell us about eosinophilic disorders?
Autorzy:
Catherine J; Department of Internal Medicine, Hôpital Erasme, 808 Route de Lennik, 1070, Brussels, Belgium. .; Institute for Medical Immunology, Université Libre de Bruxelles, 6041 Gosselies, Brussels, Belgium. .
Roufosse F; Department of Internal Medicine, Hôpital Erasme, 808 Route de Lennik, 1070, Brussels, Belgium.; Institute for Medical Immunology, Université Libre de Bruxelles, 6041 Gosselies, Brussels, Belgium.
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Źródło:
Seminars in immunopathology [Semin Immunopathol] 2021 Jun; Vol. 43 (3), pp. 439-458. Date of Electronic Publication: 2021 May 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Chemokine CCL17*
Immunity, Innate*
Humans ; Lymphocytes ; Receptors, CCR4 ; Th2 Cells
Czasopismo naukowe
Tytuł:
Safety and efficacy profile of mogamulizumab (Poteligeo) in the treatment of cancers: an update evidence from 14 studies.
Autorzy:
Zhang T; Department of Biotherapy, State Key Laboratory of Biotherapy, West China Hospital, Cancer Center, Sichuan University, No. 37 Guo Xue Alley, Chengdu, 610041, Sichuan, China.; West China Hospital, West China School of Medicine, Sichuan University, Chengdu, China.
Sun J; Qingdao central hospital, Qingdao University, Qingdao, Shandong, China.
Li J; Department of radiotherapy, Qingdao central hospital, Qingdao University, Qingdao, Shandong, China.
Zhao Y; Department of Biotherapy, State Key Laboratory of Biotherapy, West China Hospital, Cancer Center, Sichuan University, No. 37 Guo Xue Alley, Chengdu, 610041, Sichuan, China.; West China Hospital, West China School of Medicine, Sichuan University, Chengdu, China.
Zhang T; Department of Biotherapy, State Key Laboratory of Biotherapy, West China Hospital, Cancer Center, Sichuan University, No. 37 Guo Xue Alley, Chengdu, 610041, Sichuan, China.; West China Hospital, West China School of Medicine, Sichuan University, Chengdu, China.
Yang R; Department of Biotherapy, State Key Laboratory of Biotherapy, West China Hospital, Cancer Center, Sichuan University, No. 37 Guo Xue Alley, Chengdu, 610041, Sichuan, China.; West China Hospital, West China School of Medicine, Sichuan University, Chengdu, China.
Ma X; Department of Biotherapy, State Key Laboratory of Biotherapy, West China Hospital, Cancer Center, Sichuan University, No. 37 Guo Xue Alley, Chengdu, 610041, Sichuan, China. .
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Źródło:
BMC cancer [BMC Cancer] 2021 May 26; Vol. 21 (1), pp. 618. Date of Electronic Publication: 2021 May 26.
Typ publikacji:
Journal Article; Meta-Analysis
MeSH Terms:
Antibodies, Monoclonal, Humanized/*administration & dosage
Antineoplastic Combined Chemotherapy Protocols/*administration & dosage
Drug-Related Side Effects and Adverse Reactions/*epidemiology
Neoplasms/*drug therapy
Receptors, CCR4/*antagonists & inhibitors
Antibodies, Monoclonal, Humanized/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Drug-Related Side Effects and Adverse Reactions/etiology ; Humans ; Neoplasms/mortality ; Progression-Free Survival ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł:
Clinical Guidelines and New Molecular Targets for Cutaneous Lymphomas.
Autorzy:
Sugaya M; Department of Dermatology, International University of Health and Welfare, Chiba 286-8520, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 14; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 14.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Lymphoma/*metabolism
Lymphoma/*therapy
Molecular Targeted Therapy/*methods
Skin Neoplasms/*metabolism
Skin Neoplasms/*therapy
Europe ; Histone Deacetylases/metabolism ; Humans ; Interleukin-2 Receptor alpha Subunit/metabolism ; Japan ; Ki-1 Antigen/metabolism ; Lymphoma/genetics ; MicroRNAs ; Practice Guidelines as Topic ; Precision Medicine ; Receptors, CCR4/metabolism ; Sezary Syndrome/metabolism ; Sezary Syndrome/therapy ; Skin Neoplasms/genetics
Czasopismo naukowe
Tytuł:
A novel role for bone marrow-derived cells to recover damaged keratinocytes from radiation-induced injury.
Autorzy:
Okano J; Department of Plastic and Reconstructive Surgery, Shiga University of Medical Science, Shiga, Japan. .
Nakae Y; Department of Stem Cell Biology and Regenerative Medicine, Shiga University of Medical Science, Shiga, Japan.
Nakagawa T; Department of Nephrology, Otowa Hospital, Kyoto, Japan.
Katagi M; Department of Stem Cell Biology and Regenerative Medicine, Shiga University of Medical Science, Shiga, Japan.
Terashima T; Department of Stem Cell Biology and Regenerative Medicine, Shiga University of Medical Science, Shiga, Japan.
Nagakubo D; Faculty of Pharmaceutical Sciences, Division of Health and Hygienic Sciences, Himeji Dokkyo University, Hyogo, Japan.
Nakayama T; Division of Chemotherapy, Faculty of Pharmacy, Kindai University, Osaka, Japan.
Yoshie O; The Health and Kampo Institute, Miyagi, Japan.
Suzuki Y; Department of Plastic and Reconstructive Surgery, Shiga University of Medical Science, Shiga, Japan.
Kojima H; Department of Stem Cell Biology and Regenerative Medicine, Shiga University of Medical Science, Shiga, Japan.
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Źródło:
Scientific reports [Sci Rep] 2021 Mar 11; Vol. 11 (1), pp. 5653. Date of Electronic Publication: 2021 Mar 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bone Marrow Cells/*pathology
Keratinocytes/*pathology
Radiation Injuries/*pathology
Animals ; Bone Marrow Cells/radiation effects ; Bone Marrow Transplantation ; Cell Movement/radiation effects ; Cell Proliferation/radiation effects ; Chemokine CCL17/metabolism ; Dermis/pathology ; Dermis/radiation effects ; Epidermis/pathology ; Epidermis/radiation effects ; Gene Deletion ; HaCaT Cells ; Humans ; Keratinocytes/radiation effects ; Macrophages/radiation effects ; Mice, Inbred C57BL ; Mice, Transgenic ; Radiation, Ionizing ; Receptors, CCR4/deficiency ; Receptors, CCR4/metabolism ; Signal Transduction/radiation effects ; Skin/pathology ; Skin/radiation effects ; Mice
Czasopismo naukowe
Tytuł:
Serum CCL22 levels decreased in parallel with disease activity in CCR4-positive mycosis fungoides treated with mogamulizumab.
Autorzy:
Ohuchi K; Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Fujimura T; Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Lyu C; Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Amagai R; Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Muto Y; Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Aiba S; Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
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Źródło:
Dermatologic therapy [Dermatol Ther] 2020 Nov; Vol. 33 (6), pp. e14099. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lymphoma, T-Cell, Cutaneous*
Mycosis Fungoides*/drug therapy
Skin Neoplasms*/drug therapy
Antibodies, Monoclonal, Humanized ; Chemokine CCL17 ; Chemokine CCL22 ; Humans ; Receptors, CCR4
Czasopismo naukowe
Tytuł:
Immunological Properties of Atopic Dermatitis-Associated Alopecia Areata.
Autorzy:
Kageyama R; Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.
Ito T; Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.
Hanai S; Department of Dermatology, Seirei Hamamatsu General Hospital, Hamamatsu 431-3192, Japan.
Morishita N; Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.
Nakazawa S; Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.
Fujiyama T; Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.
Honda T; Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.
Tokura Y; Department of Cellular & Molecular Anatomy, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 05; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 05.
Typ publikacji:
Journal Article
MeSH Terms:
Alopecia Areata/*immunology
CD4-Positive T-Lymphocytes/*immunology
CD8-Positive T-Lymphocytes/*immunology
Dermatitis, Atopic/*immunology
Adult ; Alopecia Areata/drug therapy ; Alopecia Areata/pathology ; Antibodies, Monoclonal, Humanized/administration & dosage ; CD4-Positive T-Lymphocytes/pathology ; CD8-Positive T-Lymphocytes/pathology ; Cytokines/immunology ; Dermatitis, Atopic/drug therapy ; Dermatitis, Atopic/pathology ; Female ; Humans ; Inflammation/drug therapy ; Inflammation/immunology ; Inflammation/pathology ; Male ; Middle Aged ; Receptors, CCR4/immunology ; Receptors, CXCR3/immunology ; Young Adult
Czasopismo naukowe
Tytuł:
Recombinant CCL17-dependent CCR4 activation alleviates neuroinflammation and neuronal apoptosis through the PI3K/AKT/Foxo1 signaling pathway after ICH in mice.
Autorzy:
Deng S; Department of Critical Care Medicine, HuaShan Hospital, Fudan University, 12 middle WuLuMuQi, Shanghai, 200040, China.; Department of Physiology and Pharmacology, Center for Neuroscience Research, Loma Linda University School of Medicine, Risley Hall, Room 219, 11041 Campus Street, Loma Linda, CA, 92350, USA.
Jin P; Department of Critical Care Medicine, HuaShan Hospital, Fudan University, 12 middle WuLuMuQi, Shanghai, 200040, China.; Department of Physiology and Pharmacology, Center for Neuroscience Research, Loma Linda University School of Medicine, Risley Hall, Room 219, 11041 Campus Street, Loma Linda, CA, 92350, USA.
Sherchan P; Department of Physiology and Pharmacology, Center for Neuroscience Research, Loma Linda University School of Medicine, Risley Hall, Room 219, 11041 Campus Street, Loma Linda, CA, 92350, USA.
Liu S; Department of Physiology and Pharmacology, Center for Neuroscience Research, Loma Linda University School of Medicine, Risley Hall, Room 219, 11041 Campus Street, Loma Linda, CA, 92350, USA.; Department of Pediatrics, Shenzhen People's Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, Guangdong, China.
Cui Y; Department of Physiology and Pharmacology, Center for Neuroscience Research, Loma Linda University School of Medicine, Risley Hall, Room 219, 11041 Campus Street, Loma Linda, CA, 92350, USA.
Huang L; Department of Neurosurgery, Loma Linda University School of Medicine, Loma Linda, CA, 92350, USA.
Zhang JH; Department of Physiology and Pharmacology, Center for Neuroscience Research, Loma Linda University School of Medicine, Risley Hall, Room 219, 11041 Campus Street, Loma Linda, CA, 92350, USA.; Department of Neurosurgery, Loma Linda University School of Medicine, Loma Linda, CA, 92350, USA.; Department of Anesthesiology, Loma Linda University School of Medicine, Loma Linda, CA, 92350, USA.
Gong Y; Department of Critical Care Medicine, HuaShan Hospital, Fudan University, 12 middle WuLuMuQi, Shanghai, 200040, China. gong_.; Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200040, China. gong_.
Tang J; Department of Physiology and Pharmacology, Center for Neuroscience Research, Loma Linda University School of Medicine, Risley Hall, Room 219, 11041 Campus Street, Loma Linda, CA, 92350, USA. .
Pokaż więcej
Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2021 Mar 01; Vol. 18 (1), pp. 62. Date of Electronic Publication: 2021 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Cerebral Hemorrhage/*pathology
Chemokine CCL17/*metabolism
Neurons/*pathology
Receptors, CCR4/*metabolism
Signal Transduction/*physiology
Animals ; Apoptosis/physiology ; Brain/metabolism ; Brain/pathology ; Cerebral Hemorrhage/metabolism ; Forkhead Box Protein O1/metabolism ; Inflammation/metabolism ; Inflammation/pathology ; Male ; Mice ; Neurons/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Recombinant Proteins
Czasopismo naukowe
Tytuł:
Integrated, rational molecular replacement.
Autorzy:
Usón I; Crystallographic Methods, Institute of Molecular Biology of Barcelona (IBMB-CSIC), Baldiri Reixach 15, 08028 Barcelona, Spain.
Ballard CC; CCP4, Research Complex at Harwell, Rutherford Appleton Laboratory, Harwell Oxford, Didcot, OX11 0FA, United Kingdom.
Keegan RM; CCP4, Research Complex at Harwell, Rutherford Appleton Laboratory, Harwell Oxford, Didcot, OX11 0FA, United Kingdom.
Read RJ; Cambridge Institute for Medical Research, Department of Haematology, University of Cambridge, The Keith Peters Building, Hills Road, Cambridge, CB2 0XY, United Kingdom.
Pokaż więcej
Źródło:
Acta crystallographica. Section D, Structural biology [Acta Crystallogr D Struct Biol] 2021 Feb 01; Vol. 77 (Pt 2), pp. 129-130. Date of Electronic Publication: 2021 Feb 05.
Typ publikacji:
Congress
MeSH Terms:
Crystallography, X-Ray/*methods
Proteins/*chemistry
Protein Structural Elements ; Receptors, CCR4/chemistry

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