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Wyświetlanie 1-20 z 1491
Tytuł:
A novel transposable element-based authentication protocol for Drosophila cell lines.
Autorzy:
Mariyappa D; Biology Department, Drosophila Genomics Resource Center, Indiana University, Bloomington, IN 47405, USA.
Rusch DB; Biology Department, Center for Genetics and Bioinformatics, Indiana University, Bloomington, IN 47405, USA.
Han S; Department of Genetics and Institute of Bioinformatics, University of Georgia, Athens, GA 30602, USA.
Luhur A; Biology Department, Drosophila Genomics Resource Center, Indiana University, Bloomington, IN 47405, USA.
Overton D; Biology Department, Drosophila Genomics Resource Center, Indiana University, Bloomington, IN 47405, USA.
Miller DFB; Biology Department, Center for Genetics and Bioinformatics, Indiana University, Bloomington, IN 47405, USA.
Bergman CM; Department of Genetics and Institute of Bioinformatics, University of Georgia, Athens, GA 30602, USA.; Department of Genetics, University of Georgia, Athens, GA 30602, USA.
Zelhof AC; Biology Department, Drosophila Genomics Resource Center, Indiana University, Bloomington, IN 47405, USA.
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Źródło:
G3 (Bethesda, Md.) [G3 (Bethesda)] 2022 Feb 04; Vol. 12 (2).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Cell Line*
DNA Transposable Elements*/genetics
Drosophila*/genetics
Animals ; Drosophila melanogaster/genetics ; Genome, Insect ; Reproducibility of Results
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Transcriptome profile in Drosophila Kc and S2 embryonic cell lines.
Autorzy:
Klonaros D; Biology Department, Clark University, 950 Main Street, Worcester, MA 01610, USA.
Dresch JM; Biology Department, Clark University, 950 Main Street, Worcester, MA 01610, USA.
Drewell RA; Biology Department, Clark University, 950 Main Street, Worcester, MA 01610, USA.
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Źródło:
G3 (Bethesda, Md.) [G3 (Bethesda)] 2023 May 02; Vol. 13 (5).
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:
Drosophila*/genetics
Transcriptome*
Animals ; Drosophila melanogaster/genetics ; RNA ; Cell Line
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Indole-derived compound SIS3 targets a subset of activated Smad complexes.
Autorzy:
Itoh Y; Department of Biochemistry, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Sawaguchi T; Department of Biochemistry, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.; Research Training Program for Undergraduates, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Fu H; Department of Biochemistry, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Omata C; Department of Biochemistry, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Saitoh M; Department of Biochemistry, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.; Center for Medical Education and Science, Graduate School of Medicine, University of Yamanashi, Shmokato 1110, Chuo, Yamanashi 409-3898, Japan.
Miyazawa K; Department of Biochemistry, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
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Źródło:
Journal of biochemistry [J Biochem] 2023 Mar 31; Vol. 173 (4), pp. 283-291.
Typ publikacji:
Journal Article
MeSH Terms:
Transforming Growth Factor beta*/metabolism
Smad Proteins*/metabolism
Cell Line ; Signal Transduction ; Phosphorylation ; Smad3 Protein/genetics ; Smad2 Protein/genetics ; Smad2 Protein/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
eccDNA Atlas: a comprehensive resource of eccDNA catalog.
Autorzy:
Zhong T; School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, P.R. China.
Wang W; School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, P.R. China.
Liu H; School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, P.R. China.
Zeng M; School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, P.R. China.
Zhao X; School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, P.R. China.
Guo Z; School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, P.R. China.
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Źródło:
Briefings in bioinformatics [Brief Bioinform] 2023 Mar 19; Vol. 24 (2).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA, Circular*
DNA*
Chromosomes ; Genome ; Cell Line
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
miR-132-3p regulates antibody-mediated complement-dependent cytotoxicity in colon cancer cells by directly targeting CD55.
Autorzy:
Fan Y; Multi-omics Laboratory of Breast Diseases, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Liao J; Multi-omics Laboratory of Breast Diseases, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Wang Y; Multi-omics Laboratory of Breast Diseases, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Wang Z; Multi-omics Laboratory of Breast Diseases, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Zheng H; Multi-omics Laboratory of Breast Diseases, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Wang Y; Multi-omics Laboratory of Breast Diseases, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
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Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2023 Mar 08; Vol. 211 (1), pp. 57-67.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Colonic Neoplasms*/genetics
MicroRNAs*/genetics
Humans ; Complement Activation ; Membrane Cofactor Protein/genetics ; Membrane Cofactor Protein/metabolism ; CD59 Antigens/genetics ; CD59 Antigens/metabolism ; CD55 Antigens/genetics ; Complement System Proteins ; Cell Line, Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
GADRP: graph convolutional networks and autoencoders for cancer drug response prediction.
Autorzy:
Wang H; College of Computer Science and Electronic Engineering, Hunan University, Changsha 410082, China.
Dai C; College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China.; Department of Bioinformatics, Beijing Institute of Health Service and Transfusion Medicine, Beijing 100850, China.
Wen Y; Department of Bioinformatics, Beijing Institute of Health Service and Transfusion Medicine, Beijing 100850, China.
Wang X; College of Computer Science and Electronic Engineering, Hunan University, Changsha 410082, China.
Liu W; College of Computer Science and Electronic Engineering, Hunan University, Changsha 410082, China.
He S; Department of Bioinformatics, Beijing Institute of Health Service and Transfusion Medicine, Beijing 100850, China.
Bo X; Department of Bioinformatics, Beijing Institute of Health Service and Transfusion Medicine, Beijing 100850, China.
Peng S; College of Computer Science and Electronic Engineering, Hunan University, Changsha 410082, China.; The State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University, Changsha 410082, China.
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Źródło:
Briefings in bioinformatics [Brief Bioinform] 2023 Jan 19; Vol. 24 (1).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasms*/drug therapy
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; Benchmarking ; Cell Line ; Learning
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A systematic assessment of deep learning methods for drug response prediction: from in vitro to clinical applications.
Autorzy:
Shen B; Cancer Systems Biology group at Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Feng F; Cancer Systems Biology group at Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Li K; Cancer Systems Biology group at Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Lin P; Cancer Systems Biology group at Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Ma L; Bio-Med Big Data Center at Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Li H; Cancer Systems Biology group at Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
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Źródło:
Briefings in bioinformatics [Brief Bioinform] 2023 Jan 19; Vol. 24 (1).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Deep Learning*
Humans ; Cell Line
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CCSynergy: an integrative deep-learning framework enabling context-aware prediction of anti-cancer drug synergy.
Autorzy:
Hosseini SR; School of Biomedical Informatics, University of Texas Health Science Center (UTHealth), Houston, TX, USA.
Zhou X; School of Biomedical Informatics, University of Texas Health Science Center (UTHealth), Houston, TX, USA.
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Źródło:
Briefings in bioinformatics [Brief Bioinform] 2023 Jan 19; Vol. 24 (1).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Deep Learning*
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Drug Synergism ; Computational Biology/methods ; Cell Line, Tumor ; Drug Combinations
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Automatic recognition of protein subcellular location patterns in single cells from immunofluorescence images based on deep learning.
Autorzy:
Zhu XL; School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou 510515, China.; Guangdong Province Engineering Laboratory for Medical Imaging and Diagnostic Technology, Southern Medical University, Guangzhou 510515, China.
Bao LX; School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou 510515, China.; Guangdong Province Engineering Laboratory for Medical Imaging and Diagnostic Technology, Southern Medical University, Guangzhou 510515, China.
Xue MQ; School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou 510515, China.; Guangdong Province Engineering Laboratory for Medical Imaging and Diagnostic Technology, Southern Medical University, Guangzhou 510515, China.
Xu YY; School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou 510515, China.; Guangdong Province Engineering Laboratory for Medical Imaging and Diagnostic Technology, Southern Medical University, Guangzhou 510515, China.
Pokaż więcej
Źródło:
Briefings in bioinformatics [Brief Bioinform] 2023 Jan 19; Vol. 24 (1).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Deep Learning*
Humans ; Proteins/metabolism ; Algorithms ; Cell Line ; Fluorescent Antibody Technique
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Autorzy:
Wu X; Department of Respiratory Medicine, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, China.
Zhang H; Department of Respiratory Medicine, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, China.
Jiang G; Department of Respiratory Medicine, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, China.
Peng M; Department of Respiratory Medicine, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, China.
Li C; Department of Respiratory Medicine, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, China.
Lu J; Department of Respiratory Medicine, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, China.
Jiang S; Department of Respiratory Medicine, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, China.
Yang X; Key Laboratory of Study and Discovery of Small Targeted Drugs of Hunan Province, Changsha, China.; Department of Pharmacy, School of Medicine, Hunan Normal University, Changsha, China.
Jiang Y; Department of Respiratory Medicine, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, China.
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Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2022 Dec 31; Vol. 210 (3), pp. 309-320.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/pathology
Exosomes*/metabolism
Humans ; B7-H1 Antigen/metabolism ; Immunosuppression Therapy ; Cell Proliferation ; Cell Line, Tumor ; Cell Movement ; STAT3 Transcription Factor/metabolism ; S100 Calcium-Binding Protein A4/metabolism ; S100 Calcium-Binding Protein A4/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Compounds in cigarette smoke induce EGR1 expression via the AHR, resulting in apoptosis and COPD.
Autorzy:
Hattori N; Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan.; Department of Biochemistry, Nagasaki University School of Medicine, Nagasaki 852-8523, Japan.; Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan.
Nakagawa T; Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan.; Department of Biochemistry, Nagasaki University School of Medicine, Nagasaki 852-8523, Japan.
Yoneda M; Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan.; Department of Biochemistry, Nagasaki University School of Medicine, Nagasaki 852-8523, Japan.
Hayashida H; Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan.; Department of Biochemistry, Nagasaki University School of Medicine, Nagasaki 852-8523, Japan.
Nakagawa K; Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan.; Department of Biochemistry, Nagasaki University School of Medicine, Nagasaki 852-8523, Japan.
Yamamoto K; Biomedical Research Support Center, Nagasaki University School of Medicine, Nagasaki 852-8523, Japan.
Htun MW; Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan.; Department of Histology and Cell Biology, Nagasaki University School of Medicine, Nagasaki 852-8523, Japan.
Shibata Y; Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan.; Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan.
Koji T; Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan.; Department of Histology and Cell Biology, Nagasaki University School of Medicine, Nagasaki 852-8523, Japan.
Ito T; Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan.; Department of Biochemistry, Nagasaki University School of Medicine, Nagasaki 852-8523, Japan.
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Źródło:
Journal of biochemistry [J Biochem] 2022 Dec 05; Vol. 172 (6), pp. 365-376.
Typ publikacji:
Journal Article
MeSH Terms:
Early Growth Response Protein 1*/genetics
Early Growth Response Protein 1*/metabolism
Pulmonary Disease, Chronic Obstructive*/chemically induced
Pulmonary Disease, Chronic Obstructive*/metabolism
Nicotiana*/adverse effects
Smoke*/adverse effects
Animals ; Mice ; Apoptosis ; Lung/metabolism ; Lung/physiopathology ; Receptors, Aryl Hydrocarbon/genetics ; Receptors, Aryl Hydrocarbon/metabolism ; Humans ; Cell Line
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Predicting cell line-specific synergistic drug combinations through a relational graph convolutional network with attention mechanism.
Autorzy:
Zhang P; Department of Computer Science and Engineering, Center for Cognitive Machines and Computational Health (CMaCH), Shanghai Jiao Tong University, Shanghai 200240, China.
Tu S; Department of Computer Science and Engineering, Center for Cognitive Machines and Computational Health (CMaCH), Shanghai Jiao Tong University, Shanghai 200240, China.
Zhang W; Agricultural Bioinformatics Key Laboratory of Hubei Province, Hubei Engineering Technology Research Center of Agricultural Big Data, College of informatics, Huazhong Agricultural University, Wuhan 430070, China.
Xu L; Department of Computer Science and Engineering, Center for Cognitive Machines and Computational Health (CMaCH), Shanghai Jiao Tong University, Shanghai 200240, China.
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Źródło:
Briefings in bioinformatics [Brief Bioinform] 2022 Nov 19; Vol. 23 (6).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neural Networks, Computer*
Drug Combinations ; Cell Line
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The protein level of the tumour-promoting factor SET is regulated by cell density.
Autorzy:
Kohyanagi N; Laboratory of Veterinary Pharmacology and Laboratory of Molecular Diagnostics.
Kitamura N; Laboratory of Veterinary Pharmacology and Laboratory of Molecular Diagnostics.
Tanaka K; Laboratory of Veterinary Pharmacology and Laboratory of Molecular Diagnostics.
Mizuno T; Laboratory of Molecular Diagnostics and Therapeutics, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan.
Fujiwara N; Laboratory of Drug Discovery and Pharmacology, Faculty of Veterinary Medicine, Okayama University of Science, 794-8555 Ehime, Japan.
Ohama T; Laboratory of Veterinary Pharmacology and Laboratory of Molecular Diagnostics.
Sato K; Laboratory of Veterinary Pharmacology and Laboratory of Molecular Diagnostics.
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Źródło:
Journal of biochemistry [J Biochem] 2022 Mar 03; Vol. 171 (3), pp. 295-303.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasms*
DNA-Binding Proteins/*metabolism
Histone Chaperones/*metabolism
Cell Count ; Cell Line ; Cell Line, Tumor ; Humans ; Protein Phosphatase 2/metabolism ; Transcription Factors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Panobinostat enhances NK cell cytotoxicity in soft tissue sarcoma.
Autorzy:
Lu X; Melanoma and Sarcoma Medical Oncology Unit, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou 510060, PR China.
Liu M; Melanoma and Sarcoma Medical Oncology Unit, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou 510060, PR China.
Yang J; Melanoma and Sarcoma Medical Oncology Unit, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou 510060, PR China.
Que Y; Department of Pediatric Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, PR China.
Zhang X; Melanoma and Sarcoma Medical Oncology Unit, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou 510060, PR China.
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Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2022 Aug 19; Vol. 209 (2), pp. 127-139.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Sarcoma*/drug therapy
Animals ; Apoptosis ; Cell Line, Tumor ; Cell Proliferation ; Histone Deacetylase Inhibitors/pharmacology ; Hydroxamic Acids/pharmacology ; Killer Cells, Natural ; Panobinostat/pharmacology ; Panobinostat/therapeutic use ; beta Catenin/pharmacology ; beta Catenin/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Decreased EMILIN2 correlates to metabolism phenotype and poor prognosis of ovarian cancer.
Autorzy:
Tang X; Department of Obstetrics and Gynecology, Liaocheng People's Hospital, No. 67 Dongchang West Road, Liaocheng 252000, Shandong, China.
Li F; Department of Obstetrics and Gynecology, Liaocheng People's Hospital, No. 67 Dongchang West Road, Liaocheng 252000, Shandong, China.
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Źródło:
Journal of biochemistry [J Biochem] 2022 Jul 25; Vol. 172 (2), pp. 89-97.
Typ publikacji:
Journal Article
MeSH Terms:
Glycoproteins*/genetics
Ovarian Neoplasms*/diagnosis
Ovarian Neoplasms*/genetics
Tumor Suppressor Protein p53*/genetics
Tumor Suppressor Protein p53*/metabolism
Cell Line, Tumor ; DNA Methylation ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Phenotype ; Prognosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Down-regulation of ABCB1 by collateral sensitivity drugs reverses multidrug resistance and up-regulates enolase I.
Autorzy:
Limniatis G; Institute of Parasitology, McGill University, Quebec, Canada.
Georges E; Institute of Parasitology, McGill University, Quebec, Canada.
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Źródło:
Journal of biochemistry [J Biochem] 2022 Jun 28; Vol. 172 (1), pp. 37-48.
Typ publikacji:
Journal Article
MeSH Terms:
ATP Binding Cassette Transporter, Subfamily B*/genetics
Antineoplastic Agents*/pharmacology
Breast Neoplasms*/drug therapy
Drug Resistance, Neoplasm*
Cell Line, Tumor ; Down-Regulation ; Drug Collateral Sensitivity ; Drug Resistance, Multiple ; Female ; Humans ; Phosphopyruvate Hydratase/pharmacology ; Tamoxifen/pharmacology ; Verapamil/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Direct and indirect roles of GRWD1 in the inactivation of p53 in cancer.
Autorzy:
Ichikawa MK; Center for Medical Education and Sciences, Graduate School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo-city, Yamanashi 409-3898, Japan.; Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo-city, Yamanashi 409-3898, Japan.
Saitoh M; Center for Medical Education and Sciences, Graduate School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo-city, Yamanashi 409-3898, Japan.
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Źródło:
Journal of biochemistry [J Biochem] 2022 May 27; Vol. 171 (6), pp. 601-603.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasms*/genetics
Proto-Oncogene Proteins c-mdm2*/chemistry
Proto-Oncogene Proteins c-mdm2*/genetics
Proto-Oncogene Proteins c-mdm2*/metabolism
Carrier Proteins/metabolism ; Cell Line, Tumor ; Humans ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; Ubiquitin/metabolism ; Ubiquitination
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
cSurvival: a web resource for biomarker interactions in cancer outcomes and in cell lines.
Autorzy:
Cheng X; Centre for Molecular Medicine and Therapeutics, The University of British Columbia, Vancouver, British Columbia, Canada.; British Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Department of Medical Genetics, The University of British Columbia, Vancouver, British Columbia, Canada.
Liu Y; Centre for Molecular Medicine and Therapeutics, The University of British Columbia, Vancouver, British Columbia, Canada.; British Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Department of Medical Genetics, The University of British Columbia, Vancouver, British Columbia, Canada.
Wang J; Centre for Molecular Medicine and Therapeutics, The University of British Columbia, Vancouver, British Columbia, Canada.; British Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Department of Medical Genetics, The University of British Columbia, Vancouver, British Columbia, Canada.
Chen Y; Centre for Molecular Medicine and Therapeutics, The University of British Columbia, Vancouver, British Columbia, Canada.; British Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Department of Medical Genetics, The University of British Columbia, Vancouver, British Columbia, Canada.
Robertson AG; Canada's Michael Smith Genome Sciences Centre at BC Cancer Agency, Vancouver, British Columbia, Canada.
Zhang X; Department of Mathematics and Statistics, University of Victoria, Victoria, British Columbia, Canada.
Jones SJM; Department of Medical Genetics, The University of British Columbia, Vancouver, British Columbia, Canada.; Canada's Michael Smith Genome Sciences Centre at BC Cancer Agency, Vancouver, British Columbia, Canada.
Taubert S; Centre for Molecular Medicine and Therapeutics, The University of British Columbia, Vancouver, British Columbia, Canada.; British Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Department of Medical Genetics, The University of British Columbia, Vancouver, British Columbia, Canada.
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Źródło:
Briefings in bioinformatics [Brief Bioinform] 2022 May 13; Vol. 23 (3).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers, Tumor*/genetics
Biomarkers, Tumor*/metabolism
Lung Neoplasms*/genetics
Adult ; Cell Line ; Child ; Gene Expression Regulation, Neoplastic ; Humans ; Survival Analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A circular RNA derived from FAT atypical cadherin 3 promotes lung cancer progression via forming a regulatory loop with oncogenic ELAV like RNA binding protein 1.
Autorzy:
Jiang H; Department of Geriatrics, Shengjing Hospital of China Medical University, Shenyang City, Liaoning Province 110004, PR China.
Tian Y; Department of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang City, Liaoning Province 110032, PR China.
Zhao X; Department of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang City, Liaoning Province 110032, PR China.
Zhang L; Department of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang City, Liaoning Province 110032, PR China.
Wu Z; Department of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang City, Liaoning Province 110032, PR China.
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Źródło:
Journal of biochemistry [J Biochem] 2022 May 11; Vol. 171 (5), pp. 519-528.
Typ publikacji:
Journal Article
MeSH Terms:
Cadherins*/genetics
ELAV-Like Protein 1*/genetics
Epidermal Growth Factor*/genetics
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
RNA, Circular*/genetics
Carcinogenesis/genetics ; Cell Line, Tumor ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; MicroRNAs/genetics ; RNA-Binding Proteins/genetics
Czasopismo naukowe
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Tytuł:
Sialyl-Tn antigen facilitates extracellular vesicle-mediated transfer of FAK and enhances motility of recipient cells.
Autorzy:
Nagao K; Department of Analytical Biochemistry, Graduate School of health sciences, Kumamoto University, Kumamoto, Japan, 862-0976.
Maeda K; Department of Analytical Biochemistry, Graduate School of health sciences, Kumamoto University, Kumamoto, Japan, 862-0976.; Department of Glyco-Oncology and Medical Biochemistry, Osaka International Cancer Institute, Osaka, Japan, 541-8567.
Hosomi K; Department of Analytical Biochemistry, Graduate School of health sciences, Kumamoto University, Kumamoto, Japan, 862-0976.
Morioka K; Department of Analytical Biochemistry, Graduate School of health sciences, Kumamoto University, Kumamoto, Japan, 862-0976.
Inuzuka T; H.U. Group Research Institute G.K., Tokyo, Japan, 192-0031.
Ohtsubo K; Department of Analytical Biochemistry, Graduate School of health sciences, Kumamoto University, Kumamoto, Japan, 862-0976.; Department of Analytical Biochemistry, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan, 862-0976.
Pokaż więcej
Źródło:
Journal of biochemistry [J Biochem] 2022 May 11; Vol. 171 (5), pp. 543-554.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, Tumor-Associated, Carbohydrate*/metabolism
Extracellular Vesicles*/metabolism
Biomarkers, Tumor/metabolism ; Cell Line, Tumor
Czasopismo naukowe
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Wyświetlanie 1-20 z 1491

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