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Tytuł :
Effects of Visfatin on Intracellular Mechanics and Catabolism in Human Primary Chondrocytes through Glycogen Synthase Kinase 3β Inactivation.
Autorzy :
Chang SF; Department of Medical Research and Development, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan.
Huang KC; Department of Orthopaedics, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan.; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Lee KH; Department of Pharmacy, Chia Nan University of Pharmacy and Science, Tainan 717, Taiwan.
Chiang YC; Chronic Diseases and Health Promotion Research Center, Division of Basic Medical Sciences, Department of Nursing, Chang Gung University of Science and Technology, Chiayi 613, Taiwan.
Lee WR; Department of Engineering and System Science, National Tsing Hua University, Hsinchu 300, Taiwan.
Hsieh RZ; Department of Medical Research and Development, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan.; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Su YP; Department of Orthopaedics and Traumatology, Veterans General Hospital, Taipei 112, Taiwan.; Department of Surgery, School of Medicine, National Yang-Ming University, Taipei 112, Taiwan.
Wu SC; Department of Engineering and System Science, National Tsing Hua University, Hsinchu 300, Taiwan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 28; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 28.
Typ publikacji :
Journal Article
MeSH Terms :
Chondrocytes*/metabolism
Chondrocytes*/pathology
Osteoarthritis*/metabolism
Osteoarthritis*/pathology
Cytokines/*physiology
Glycogen Synthase Kinase 3 beta/*metabolism
Nicotinamide Phosphoribosyltransferase/*physiology
Actin Cytoskeleton/metabolism ; Cells, Cultured ; Humans ; Microtubules/metabolism ; Primary Cell Culture
Czasopismo naukowe
Tytuł :
Comparative Study of DHA with Different Molecular Forms for Ameliorating Osteoporosis by Promoting Chondrocyte-to-Osteoblast Transdifferentiation in the Growth Plate of Ovariectomized Mice.
Autorzy :
Zhang T; College of Food Science and Engineering, Ocean University of China, Qingdao 266003, Shandong, China.
Tian Y; College of Food Science and Engineering, Ocean University of China, Qingdao 266003, Shandong, China.; Marine Biomedical Research Institute of Qingdao, Qingdao 266071, Shandong, China.
Wang Q; College of Food Science and Engineering, Ocean University of China, Qingdao 266003, Shandong, China.
Fu M; College of Food Science and Engineering, Ocean University of China, Qingdao 266003, Shandong, China.
Xue C; College of Food Science and Engineering, Ocean University of China, Qingdao 266003, Shandong, China.
Wang J; College of Food Science and Engineering, Ocean University of China, Qingdao 266003, Shandong, China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2021 Sep 15; Vol. 69 (36), pp. 10562-10571. Date of Electronic Publication: 2021 Aug 31.
Typ publikacji :
Journal Article
MeSH Terms :
Chondrocytes*
Osteoporosis*/drug therapy
Osteoporosis*/genetics
Animals ; Cell Differentiation ; Cell Transdifferentiation ; Docosahexaenoic Acids ; Female ; Growth Plate ; Mice ; Osteoblasts ; Osteogenesis
Czasopismo naukowe
Tytuł :
Effects of ibuprofen on gene expression in chondrocytes from patients with osteoarthritis as determined by RNA-Seq.
Autorzy :
Pemmari A; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, Tampere, Finland.
Tuure L; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, Tampere, Finland.
Hämäläinen M; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, Tampere, Finland.
Leppänen T; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, Tampere, Finland.
Moilanen T; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, Tampere, Finland.; Coxa Hospital for Joint Replacement, Tampere, Finland.
Moilanen E; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, Tampere, Finland .
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Źródło :
RMD open [RMD Open] 2021 Sep; Vol. 7 (3).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chondrocytes*
Osteoarthritis*/drug therapy
Osteoarthritis*/genetics
Cells, Cultured ; Gene Expression ; Humans ; Ibuprofen/pharmacology ; Ibuprofen/therapeutic use ; RNA-Seq
Czasopismo naukowe
Tytuł :
The influence of chondrocyte source on the manufacturing reproducibility of human tissue engineered cartilage.
Autorzy :
Middendorf JM; Sibley School of Mechanical Engineering, Cornell University, Ithaca, NY, United States.
Diamantides N; Meinig School of Biomedical Engineering Cornell University, Ithaca, NY, United States.
Kim B; Sibley School of Mechanical Engineering, Cornell University, Ithaca, NY, United States.
Dugopolski C; Histogenics Corporation, Waltham, MA, United States.
Kennedy S; Histogenics Corporation, Waltham, MA, United States.
Blahut E; Histogenics Corporation, Waltham, MA, United States.
Cohen I; Department of Physics, Cornell University, Ithaca, NY, United States.
Bonassar LJ; Sibley School of Mechanical Engineering, Cornell University, Ithaca, NY, United States; Meinig School of Biomedical Engineering Cornell University, Ithaca, NY, United States. Electronic address: .
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Źródło :
Acta biomaterialia [Acta Biomater] 2021 Sep 01; Vol. 131, pp. 276-285. Date of Electronic Publication: 2021 Jul 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cartilage, Articular*
Chondrocytes*
Cartilage ; Friction ; Humans ; Pressure ; Reproducibility of Results ; Tissue Engineering
Czasopismo naukowe
Tytuł :
Oxygen-generating microparticles in chondrocytes-laden hydrogels by facile and versatile click chemistry strategy.
Autorzy :
de Sousa Araújo E; LIMAV-Interdisciplinary Laboratory for Advanced Materials, BioMatLab, UFPI - Federal University of Piaui, Teresina, PI, 64049-550, Brazil.
Domingues Stocco T; Faculty of Medical Sciences, Unicamp - State University of Campinas, Campinas, SP, 13083-877, Brazil; University of Santo Amaro, São Paulo, SP, 04829-300, Brazil.
Fernandes de Sousa G; LIMAV-Interdisciplinary Laboratory for Advanced Materials, BioMatLab, UFPI - Federal University of Piaui, Teresina, PI, 64049-550, Brazil.
Afewerki S; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, United States; Division of Health Sciences and Technology, Harvard University ‒ Massachusetts Institute of Technology (MIT), Cambridge, MA, 02139, United States. Electronic address: .
Marciano FR; Department of Physics, UFPI - Federal University of Piaui, Teresina, PI, 64049-550, Brazil.
Alexandre Finzi Corat M; Multidisciplinary Center for Biological Research, Unicamp - State University of Campinas, Campinas, SP, 13083-877, Brazil.
Michelle Machado de Paula M; Multidisciplinary Center for Biological Research, Unicamp - State University of Campinas, Campinas, SP, 13083-877, Brazil.
Ferreira Cândido Lima Verde T; LIMAV-Interdisciplinary Laboratory for Advanced Materials, BioMatLab, UFPI - Federal University of Piaui, Teresina, PI, 64049-550, Brazil.
Cristina Moreira Silva M; Multidisciplinary Center for Biological Research, Unicamp - State University of Campinas, Campinas, SP, 13083-877, Brazil.
Oliveira Lobo A; LIMAV-Interdisciplinary Laboratory for Advanced Materials, BioMatLab, UFPI - Federal University of Piaui, Teresina, PI, 64049-550, Brazil; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, United States. Electronic address: .
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Źródło :
Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2021 Sep; Vol. 205, pp. 111850. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Chondrocytes*
Hydrogels*
Click Chemistry ; Oxygen ; Tissue Engineering
Czasopismo naukowe
Tytuł :
Enhanced miRNA-140 expression of osteoarthritis-affected human chondrocytes cultured in a polymer based three-dimensional (3D) matrix.
Autorzy :
Katoh S; Edogawa Evolutionary Lab of Science, Edogawa Hospital Campus, 2-24-18, Higashi Koiwa, Edogawa, Tokyo 133-0052, Japan; Department of Orthopaedic Surgery, Edogawa Hospital, 2-24-18, Higashi Koiwa, Edogawa, Tokyo 133-0052, Japan.
Yoshioka H; Mebiol Inc., 1-25-8, Nakahara, Hiratsuka 254-0075, Kanagawa, Japan.
Senthilkumar R; The Fujio-Eiji Academic Terrain (FEAT), Nichi-In Centre for Regenerative Medicine (NCRM), PB 1262, Chennai 600034, Tamil Nadu, India.
Preethy S; The Fujio-Eiji Academic Terrain (FEAT), Nichi-In Centre for Regenerative Medicine (NCRM), PB 1262, Chennai 600034, Tamil Nadu, India.
Abraham SJK; The Mary-Yoshio Translational Hexagon (MYTH), Nichi-In Centre for Regenerative Medicine (NCRM), PB 1262, Chennai 600034, Tamil Nadu, India; JBM Inc., 3-1-14, Higashi Koiwa, Edogawa, Tokyo 133-0052, Japan; University of Yamanashi -Faculty of Medicine, 1110, Shimokato, Chuo, Yamanashi 409-3898, Japan; GN Corporation Co. Ltd., 3-8, Wakamatsu, Kofu, Yamanashi 400-0866, Japan. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Aug 01; Vol. 278, pp. 119553. Date of Electronic Publication: 2021 Apr 29.
Typ publikacji :
Journal Article
MeSH Terms :
Up-Regulation*
Chondrocytes/*pathology
MicroRNAs/*genetics
Osteoarthritis/*genetics
Cell Culture Techniques ; Cells, Cultured ; Chondrocytes/metabolism ; Humans ; Osteoarthritis/pathology ; Polymers/chemistry ; Tissue Scaffolds/chemistry
Czasopismo naukowe
Tytuł :
Bioorthogonal hydroxyethyl cellulose-based scaffold crosslinked via click chemistry for cartilage tissue engineering applications.
Autorzy :
Nouri-Felekori M; Biomaterials Research Group, Nanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC), Alborz, Iran.
Nezafati N; Biomaterials Research Group, Nanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC), Alborz, Iran. Electronic address: .
Moraveji M; Biomaterials Research Group, Nanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC), Alborz, Iran.
Hesaraki S; Biomaterials Research Group, Nanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC), Alborz, Iran.
Ramezani T; Biomaterials Research Group, Nanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC), Alborz, Iran.
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jul 31; Vol. 183, pp. 2030-2043. Date of Electronic Publication: 2021 Jun 04.
Typ publikacji :
Journal Article
MeSH Terms :
Click Chemistry*
Tissue Engineering*
Tissue Scaffolds*
Biocompatible Materials/*chemistry
Cartilage/*physiology
Cellulose/*analogs & derivatives
Chondrocytes/*physiology
Cross-Linking Reagents/*chemistry
Cartilage/metabolism ; Cartilage/ultrastructure ; Cell Adhesion ; Cell Line ; Cell Survival ; Cellulose/chemistry ; Chondrocytes/metabolism ; Chondrocytes/ultrastructure ; Chondrogenesis ; Citric Acid/chemistry ; Elastic Modulus ; Humans ; Porosity ; Tensile Strength
Czasopismo naukowe
Tytuł :
Δ -Ergostenol Glycoside Derivatives Inhibit the Expression of Inflammatory Mediators and Matrix Metalloproteinase.
Autorzy :
Moon H; Global Center for Pharmaceutical Ingredient Materials, Department of Applied Chemistry, Kyung Hee University, Yongin 17104, Korea.
Ko M; Global Center for Pharmaceutical Ingredient Materials, Department of Applied Chemistry, Kyung Hee University, Yongin 17104, Korea.
Park Y; Graduate School of East-West Medicinal Science, Kyung Hee University, Yongin 17104, Korea.
Kim J; Global Center for Pharmaceutical Ingredient Materials, Department of Applied Chemistry, Kyung Hee University, Yongin 17104, Korea.
Yoon D; Global Center for Pharmaceutical Ingredient Materials, Department of Applied Chemistry, Kyung Hee University, Yongin 17104, Korea.
Lee E; Graduate School of East-West Medicinal Science, Kyung Hee University, Yongin 17104, Korea.
Lee T; Global Center for Pharmaceutical Ingredient Materials, Department of Applied Chemistry, Kyung Hee University, Yongin 17104, Korea.
Kim H; Global Center for Pharmaceutical Ingredient Materials, Department of Applied Chemistry, Kyung Hee University, Yongin 17104, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 28; Vol. 26 (15). Date of Electronic Publication: 2021 Jul 28.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Chondrocytes/*drug effects
Ergosterol/*pharmacology
Gene Expression Regulation/*drug effects
Glycosides/*pharmacology
Synoviocytes/*drug effects
Anti-Inflammatory Agents/chemistry ; Cell Line ; Cell Survival/drug effects ; Chondrocytes/cytology ; Chondrocytes/metabolism ; Collagen Type II/genetics ; Collagen Type II/metabolism ; Ergosterol/chemistry ; Glycosides/chemical synthesis ; Humans ; Inflammation/prevention & control ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Interleukin-8/genetics ; Interleukin-8/metabolism ; Matrix Metalloproteinases/genetics ; Matrix Metalloproteinases/metabolism ; Models, Biological ; Nitric Oxide Synthase Type II/genetics ; Nitric Oxide Synthase Type II/metabolism ; Signal Transduction ; Synoviocytes/cytology ; Synoviocytes/metabolism ; Tumor Necrosis Factor-alpha/antagonists & inhibitors ; Tumor Necrosis Factor-alpha/pharmacology
Czasopismo naukowe
Tytuł :
Downregulation of MicroRNA-495 Alleviates IL-1β Responses among Chondrocytes by Preventing SOX9 Reduction.
Autorzy :
Joung S; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Yoon DS; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.
Cho S; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Ko EA; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.
Lee KM; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.
Park KH; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.
Lee JW; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.
Kim SH; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.; Arthroscopy and Joint Research Institute, Yonsei University College of Medicine, Seoul, Korea.; Department of Orthopedic Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. .
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Źródło :
Yonsei medical journal [Yonsei Med J] 2021 Jul; Vol. 62 (7), pp. 650-659.
Typ publikacji :
Journal Article
MeSH Terms :
Chondrocytes*/metabolism
Interleukin-1beta*/metabolism
MicroRNAs*/genetics
SOX9 Transcription Factor*/genetics
SOX9 Transcription Factor*/metabolism
Cells, Cultured ; Down-Regulation ; Humans
Czasopismo naukowe
Tytuł :
Role of Matrix-Associated Autologous Chondrocyte Implantation with Spheroids in the Treatment of Large Chondral Defects in the Knee: A Systematic Review.
Autorzy :
Vonk LA; CO.DON AG, 14513 Teltow, Germany.; Department of Orthopaedics, University Medical Center Utrecht, Utrecht University, 3584 CX Utrecht, The Netherlands.
Roël G; CO.DON AG, 14513 Teltow, Germany.
Hernigou J; Department of Orthopedic Surgery, EpiCURA Hospital, 7331 Baudour, Belgium.; Laboratory of Bone and Metabolic Biochemistry, Faculty of Medecine, Université Libre de Bruxelles, 1070 Brussels, Belgium.
Kaps C; CO.DON AG, 14513 Teltow, Germany.
Hernigou P; Department of Orthopaedic Surgery, Faculty of Medicine, UPEC (University Paris-Est, Créteil), 94000 Créteil, France.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 01; Vol. 22 (13). Date of Electronic Publication: 2021 Jul 01.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Chondrocytes/*transplantation
Animals ; Cartilage Diseases/surgery ; Cartilage Diseases/therapy ; Cartilage, Articular/surgery ; Cell- and Tissue-Based Therapy/methods ; Chondrocytes/cytology ; Chondrocytes/metabolism ; Extracellular Matrix/metabolism ; Extracellular Matrix/pathology ; Humans ; Knee Injuries/surgery ; Knee Injuries/therapy ; Knee Joint/metabolism ; Knee Joint/pathology ; Orthopedic Procedures/methods ; Osteoarthritis, Knee/metabolism ; Osteoarthritis, Knee/pathology ; Osteoarthritis, Knee/therapy ; Spheroids, Cellular ; Transplantation, Autologous
Czasopismo naukowe
Tytuł :
Soluble inflammatory mediators of synoviocytes stimulated by monosodium urate crystals induce the production of oxidative stress, pain, and inflammation mediators in chondrocytes : Secretome of synoviocytes induces chondrocyte damage.
Autorzy :
López-Reyes A; Gerosciences Laboratory, National Institute of Rehabilitation Luis Guillermo Ibarra-Ibarra, Ministry of Public Health, Calzada Mexico-Xochimilco 289, C.P.14389, Tlalpan, Mexico City, Mexico. .; School of Health Sciences, Anahuac Mexico University, South Campus, Mexico City, Mexico. .
Medina-Luna D; Gerosciences Laboratory, National Institute of Rehabilitation Luis Guillermo Ibarra-Ibarra, Ministry of Public Health, Calzada Mexico-Xochimilco 289, C.P.14389, Tlalpan, Mexico City, Mexico.; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.
Santamaría-Olmedo M; Gerosciences Laboratory, National Institute of Rehabilitation Luis Guillermo Ibarra-Ibarra, Ministry of Public Health, Calzada Mexico-Xochimilco 289, C.P.14389, Tlalpan, Mexico City, Mexico.; Synovial Fluid Laboratory, National Institute of Rehabilitation Luis Guillermo Ibarra-Ibarra, Ministry of Public Health, Calzada Mexico-Xochimilco 289, Tlalpan, Mexico City, Mexico.
Martínez-Flores K; Synovial Fluid Laboratory, National Institute of Rehabilitation Luis Guillermo Ibarra-Ibarra, Ministry of Public Health, Calzada Mexico-Xochimilco 289, Tlalpan, Mexico City, Mexico.
Zamudio-Cuevas Y; Synovial Fluid Laboratory, National Institute of Rehabilitation Luis Guillermo Ibarra-Ibarra, Ministry of Public Health, Calzada Mexico-Xochimilco 289, Tlalpan, Mexico City, Mexico.
Fernández-Torres J; Synovial Fluid Laboratory, National Institute of Rehabilitation Luis Guillermo Ibarra-Ibarra, Ministry of Public Health, Calzada Mexico-Xochimilco 289, Tlalpan, Mexico City, Mexico.
Martínez-Nava GA; Gerosciences Laboratory, National Institute of Rehabilitation Luis Guillermo Ibarra-Ibarra, Ministry of Public Health, Calzada Mexico-Xochimilco 289, C.P.14389, Tlalpan, Mexico City, Mexico.; Synovial Fluid Laboratory, National Institute of Rehabilitation Luis Guillermo Ibarra-Ibarra, Ministry of Public Health, Calzada Mexico-Xochimilco 289, Tlalpan, Mexico City, Mexico.
Olivos-Meza A; Arthroscopy Service, National Institute of Rehabilitation Luis Guillermo Ibarra-Ibarra, Ministry of Public Health, Calzada Mexico-Xochimilco 289, Tlalpan, Mexico City, Mexico.
Camacho-Rea C; Department of Animal Nutrition, National Institute of Medical Sciences and Nutrition Salvador Zubirán (INCMNSZ), Vasco de Quiroga, No.15, Tlalpan, Mexico City, Mexico.
Fernández-Moreno M; Rheumatology Service, Research Department, INIBIC, CIBER-BBN, A Coruña, Spain.
Blanco FJ; Rheumatology Service, Research Department, INIBIC, CIBER-BBN, A Coruña, Spain.
Pineda C; Department of Rheumatic and Musculoskeletal Diseases, National Institute of Rehabilitation Luis Guillermo Ibarra-Ibarra, Mexico City, Mexico.
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Źródło :
Clinical rheumatology [Clin Rheumatol] 2021 Aug; Vol. 40 (8), pp. 3265-3271. Date of Electronic Publication: 2021 Mar 16.
Typ publikacji :
Journal Article
MeSH Terms :
Chondrocytes*
Synoviocytes*
Cells, Cultured ; Humans ; Hydrogen Peroxide ; Inflammation Mediators ; Oxidative Stress ; Pain ; Uric Acid
Czasopismo naukowe
Tytuł :
Dynamic loading enhances chondrogenesis of human chondrocytes within a biodegradable resilient hydrogel.
Autorzy :
Xie M; Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15217, USA. , Xiangya Hospital, Central South University, Changsha, Hunan Province 410008, China.
Fritch M; Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15217, USA. .
He Y; Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15217, USA. .
Fu H; Department of Bioengineering, University of Texas at Arlington, Arlington, TX 76019, USA. .
Hong Y; Department of Bioengineering, University of Texas at Arlington, Arlington, TX 76019, USA. .
Lin H; Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15217, USA. and Department of Bioengineering, University of Pittsburgh Swanson School of Engineering, Pittsburgh, PA 15219, USA and McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.
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Źródło :
Biomaterials science [Biomater Sci] 2021 Jul 13; Vol. 9 (14), pp. 5011-5024.
Typ publikacji :
Journal Article
MeSH Terms :
Chondrocytes*
Chondrogenesis*
Animals ; Cartilage ; Cells, Cultured ; Humans ; Hydrogels ; Ion Channels ; Mice ; TRPV Cation Channels ; Tissue Engineering ; Tissue Scaffolds
Czasopismo naukowe
Tytuł :
Chondroprotective Effects of a Histone Deacetylase Inhibitor, Panobinostat, on Pain Behavior and Cartilage Degradation in Anterior Cruciate Ligament Transection-Induced Experimental Osteoarthritic Rats.
Autorzy :
Wen ZH; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 80424, Taiwan.
Huang JS; Section of Orthopedics, Department of Surgery, Antai Medical Care Corporation Anti Tian-Sheng Memorial Hospital, PingTong 92842, Taiwan.
Lin YY; Department of Sports Medicine, China Medical University, No. 91 Hsueh-Shih Road, Taichung 40402, Taiwan.
Yao ZK; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 80424, Taiwan.; Department of Orthopedics, Kaohsiung Veterans General Hospital, Kaohsiung 81341, Taiwan.
Lai YC; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 80424, Taiwan.; Department of Orthopedics, Asia University Hospital, Taichung 41354, Taiwan.
Chen WF; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 80424, Taiwan.; Department of Neurosurgery, College of Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, Kaohsiung 83301, Taiwan.
Liu HT; Department of Medical Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.
Lin SC; Department of Orthopedic Surgery, Pingtung Christian Hospital, No. 60 Dalian Road, Pingtung 90059, Taiwan.
Tsai YC; National Museum of Marine Biology and Aquarium, Pingtung 94450, Taiwan.
Tsai TC; Section of Nephrology, Department of Medicine, Antai Medical Care Corporation Anti Tian-Sheng Memorial Hospital, Pingtung 92842, Taiwan.
Jean YH; Section of Orthopedics, Department of Surgery, Antai Medical Care Corporation Anti Tian-Sheng Memorial Hospital, PingTong 92842, Taiwan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 07; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Journal Article
MeSH Terms :
Anterior Cruciate Ligament/*drug effects
Cartilage, Articular/*drug effects
Chondrocytes/*drug effects
Histone Deacetylase Inhibitors/*pharmacology
Osteoarthritis, Knee/*drug therapy
Pain/*drug therapy
Panobinostat/*pharmacology
Animals ; Anterior Cruciate Ligament/metabolism ; Anterior Cruciate Ligament Injuries/drug therapy ; Anterior Cruciate Ligament Injuries/metabolism ; Cartilage Diseases/drug therapy ; Cartilage Diseases/metabolism ; Cartilage, Articular/metabolism ; Chondrocytes/metabolism ; Disease Models, Animal ; Male ; Osteoarthritis, Knee/metabolism ; Pain/metabolism ; Rats ; Rats, Wistar ; Weight-Bearing
Czasopismo naukowe
Tytuł :
Effects of Extracellular Vesicles from Blood-Derived Products on Osteoarthritic Chondrocytes within an Inflammation Model.
Autorzy :
Otahal A; Center for Regenerative Medicine, Danube University Krems, 3500 Krems, Austria.
Kramer K; Center for Regenerative Medicine, Danube University Krems, 3500 Krems, Austria.
Kuten-Pella O; OrthoSera GmbH, 3500 Krems, Austria.
Moser LB; Center for Regenerative Medicine, Danube University Krems, 3500 Krems, Austria.
Neubauer M; Center for Regenerative Medicine, Danube University Krems, 3500 Krems, Austria.
Lacza Z; OrthoSera GmbH, 3500 Krems, Austria.; Institute of Sport and Health Sciences, University of Physical Education, 1123 Budapest, Hungary.
Nehrer S; Center for Regenerative Medicine, Danube University Krems, 3500 Krems, Austria.
De Luna A; Center for Regenerative Medicine, Danube University Krems, 3500 Krems, Austria.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 05; Vol. 22 (13). Date of Electronic Publication: 2021 Jul 05.
Typ publikacji :
Journal Article
MeSH Terms :
Chondrocytes/*immunology
Extracellular Vesicles/*immunology
Osteoarthritis/*therapy
Chondrocytes/metabolism ; Coculture Techniques ; Female ; Gene Expression Profiling ; Humans ; Inflammation/immunology ; Inflammation/therapy ; Injections, Intra-Articular ; Interleukin-1beta/metabolism ; Male ; Models, Biological ; Monocytes/immunology ; Osteoarthritis/genetics ; Osteoarthritis/immunology ; Regenerative Medicine/methods ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Primary Autologous Chondrocyte Implantation of the Knee Versus Autologous Chondrocyte Implantation After Failed Marrow Stimulation: A Systematic Review.
Autorzy :
Schuette HB; Department of Orthopedics, OhioHealth/Doctors Hospital, Columbus, Ohio, USA.
Kraeutler MJ; Department of Orthopaedic Surgery, St. Joseph's University Medical Center, Paterson, New Jersey, USA.
Schrock JB; Marian University College of Osteopathic Medicine, Indianapolis, Indiana, USA.
McCarty EC; Department of Orthopedics, University of Colorado School of Medicine, Aurora, Colorado, USA.
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Źródło :
The American journal of sports medicine [Am J Sports Med] 2021 Jul; Vol. 49 (9), pp. 2536-2541. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Cartilage, Articular*/surgery
Chondrocytes*
Activities of Daily Living ; Adult ; Bone Marrow ; Humans ; Knee Joint/surgery ; Transplantation, Autologous
Czasopismo naukowe
Tytuł :
Long-term exposure to the fluoride blocks the development of chondrocytes in the ducks: The molecular mechanism of fluoride regulating autophagy and apoptosis.
Autorzy :
Wang Y; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Li A; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Mehmood K; Faculty of Veterinary & Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
Hussain R; Faculty of Veterinary & Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
Abbas RZ; Department of Parasitology, Faculty of Veterinary Science, University of Agriculture, Faisalabad 38040, Pakistan.
Javed MT; Department of Pathology, Faculty of Veterinary Science, University of Agriculture, Faisalabad 38040, Pakistan.
Chang YF; College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Hu L; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Pan J; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Li Y; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Shi L; Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China. Electronic address: .
Tang Z; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. Electronic address: .
Zhang H; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Jul 01; Vol. 217, pp. 112225. Date of Electronic Publication: 2021 Apr 14.
Typ publikacji :
Journal Article
MeSH Terms :
Chondrocytes/*physiology
Ducks/*physiology
Fluorides/*toxicity
Animals ; Apoptosis/drug effects ; Autophagy/drug effects ; Beclin-1/metabolism ; Chondrocytes/drug effects ; Chondrogenesis ; Fluorides/metabolism ; Growth Plate
Czasopismo naukowe
Tytuł :
FOXO1 expression in chondrocytes modulates cartilage production and removal in fracture healing.
Autorzy :
Ding Z; Department of Pediatric Dentistry, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, China; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Qiu M; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Orthopaedic Surgery, Shengjing Hospital, China Medical University, Shenyang, China.
Alharbi MA; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Endodontics, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.
Huang T; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Pei X; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA; First Clinical Division, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, China.
Milovanova TN; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jiao H; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Lu C; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Liu M; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Qin L; McKay Orthopaedic Research Laboratory, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Graves DT; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: .
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Źródło :
Bone [Bone] 2021 Jul; Vol. 148, pp. 115905. Date of Electronic Publication: 2021 Mar 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Chondrocytes*
Fracture Healing*
Animals ; Bony Callus ; Cartilage ; Forkhead Box Protein O1/genetics ; Mice ; Osteoclasts
Czasopismo naukowe
Tytuł :
Keep your Sox on, chondrocytes!
Autorzy :
Pitsillides AA; Skeletal Biology Group, Department of Comparative Biomedical Sciences, Royal Veterinary College, London, UK. .
Beier F; Department of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada. .; Bone and Joint Institute, University of Western Ontario, London, Ontario, Canada. .
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Źródło :
Nature reviews. Rheumatology [Nat Rev Rheumatol] 2021 Jul; Vol. 17 (7), pp. 383-384.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Chondrocytes*
Cell Differentiation ; Humans
Czasopismo naukowe
Tytuł :
Comparison of chondro-inductivity between collagen and hyaluronic acid hydrogel based on chemical/physical microenvironment.
Autorzy :
Yang J; National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 61004, Sichuan, China; Research Center for Human Tissue and Organs Degeneration, Institute Biomedical and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangzhou, China.
Tang Z; National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 61004, Sichuan, China.
Liu Y; National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 61004, Sichuan, China.
Luo Z; National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 61004, Sichuan, China.
Xiao Y; National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 61004, Sichuan, China. Electronic address: .
Zhang X; National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 61004, Sichuan, China.
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jul 01; Vol. 182, pp. 1941-1952. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Cellular Microenvironment/*drug effects
Chondrocytes/*cytology
Collagen/*pharmacology
Hyaluronic Acid/*pharmacology
Hydrogels/*pharmacology
Adsorption ; Animals ; Biomechanical Phenomena ; Blood Proteins/metabolism ; Cattle ; Cell Differentiation/drug effects ; Cell Shape/drug effects ; Cell Survival/drug effects ; Chondrocytes/drug effects ; Chondrogenesis/drug effects ; Diffusion ; Extracellular Matrix/drug effects ; Extracellular Matrix/metabolism ; Gene Expression Regulation/drug effects ; Mesenchymal Stem Cells/cytology ; Mesenchymal Stem Cells/drug effects ; Mesenchymal Stem Cells/metabolism ; Rabbits ; Static Electricity ; Transforming Growth Factor beta1/metabolism
Czasopismo naukowe
Tytuł :
Study of fucoidans as natural biomolecules for therapeutical applications in osteoarthritis.
Autorzy :
Vaamonde-García C; Tissue Engineering and Cellular Therapy Group, Department of Physiotherapy, Medicine and Biological Sciences, University of A Coruña, A Coruña, Spain; Unidad de Medicina Regenerativa, Grupo de Investigación de Reumatología (GIR), Instituto de InvestigaciónBiomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), C/ As Xubias de Arriba 84, 15006, A Coruña, España; Centro de Investigaciones Científicas Avanzadas (CICA), As Carballeiras S/N, Campus de Elviña, 15071, A Coruña, España. Electronic address: .
Flórez-Fernández N; Department of Chemical Engineering, University of Vigo, Faculty of Sciences, Ourense, Spain; CINBIO, Universidade de Vigo, Departamento de Ingeniería Química, Campus Ourense, 32004 Ourense, Spain. Electronic address: .
Torres MD; Department of Chemical Engineering, University of Vigo, Faculty of Sciences, Ourense, Spain; CINBIO, Universidade de Vigo, Departamento de Ingeniería Química, Campus Ourense, 32004 Ourense, Spain. Electronic address: .
Lamas-Vázquez MJ; Tissue Engineering and Cellular Therapy Group, Department of Physiotherapy, Medicine and Biological Sciences, University of A Coruña, A Coruña, Spain. Electronic address: .
Blanco FJ; Unidad de Medicina Regenerativa, Grupo de Investigación de Reumatología (GIR), Instituto de InvestigaciónBiomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), C/ As Xubias de Arriba 84, 15006, A Coruña, España; Centro de Investigaciones Científicas Avanzadas (CICA), As Carballeiras S/N, Campus de Elviña, 15071, A Coruña, España. Electronic address: .
Domínguez H; Department of Chemical Engineering, University of Vigo, Faculty of Sciences, Ourense, Spain; CINBIO, Universidade de Vigo, Departamento de Ingeniería Química, Campus Ourense, 32004 Ourense, Spain. Electronic address: .
Meijide-Faílde R; Tissue Engineering and Cellular Therapy Group, Department of Physiotherapy, Medicine and Biological Sciences, University of A Coruña, A Coruña, Spain; Centro de Investigaciones Científicas Avanzadas (CICA), As Carballeiras S/N, Campus de Elviña, 15071, A Coruña, España. Electronic address: .
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Źródło :
Carbohydrate polymers [Carbohydr Polym] 2021 Apr 15; Vol. 258, pp. 117692. Date of Electronic Publication: 2021 Jan 26.
Typ publikacji :
Journal Article
MeSH Terms :
Cartilage, Articular/*drug effects
Chondrocytes/*drug effects
Osteoarthritis/*drug therapy
Polysaccharides/*chemistry
Synoviocytes/*drug effects
Aged ; Aged, 80 and over ; Antioxidants/chemistry ; Apoptosis/drug effects ; Chondrocytes/cytology ; Chondrocytes/metabolism ; Female ; Fibroblasts/metabolism ; Fucose/chemistry ; Fucus ; Humans ; In Vitro Techniques ; Macrocystis ; Male ; Membrane Potential, Mitochondrial ; Middle Aged ; Oligosaccharides/chemistry ; Osteoarthritis/metabolism ; Phloroglucinol/chemistry ; Reactive Oxygen Species ; Rheumatic Diseases/immunology ; Sulfates/chemistry ; Synoviocytes/cytology ; Undaria
Czasopismo naukowe

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