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Tytuł :
A Complex of U1 snRNP with Cleavage and Polyadenylation Factors Controls Telescripting, Regulating mRNA Transcription in Human Cells.
Autorzy :
So BR; Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA.
Di C; Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA.
Cai Z; Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA.
Venters CC; Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA.
Guo J; Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA.
Oh JM; Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA.
Arai C; Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA.
Dreyfuss G; Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2019 Nov 21; Vol. 76 (4), pp. 590-599.e4. Date of Electronic Publication: 2019 Sep 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
RNA Cleavage*
Transcription, Genetic*
Cell Nucleus/*metabolism
Cleavage And Polyadenylation Specificity Factor/*metabolism
RNA Precursors/*biosynthesis
RNA, Messenger/*biosynthesis
Ribonucleoprotein, U1 Small Nuclear/*metabolism
3' Untranslated Regions ; Active Transport, Cell Nucleus ; Binding Sites ; Cell Nucleus/genetics ; Cleavage And Polyadenylation Specificity Factor/genetics ; Cleavage Stimulation Factor/genetics ; Cleavage Stimulation Factor/metabolism ; HeLa Cells ; Humans ; Multiprotein Complexes ; Poly A/metabolism ; Protein Binding ; RNA Precursors/genetics ; RNA, Messenger/genetics ; Ribonucleoprotein, U1 Small Nuclear/genetics
Czasopismo naukowe
Tytuł :
Common Kinetic Mechanism of Abasic Site Recognition by Structurally Different Apurinic/Apyrimidinic Endonucleases.
Autorzy :
Kuznetsova AA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Senchurova SI; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.; Department of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia.
Ishchenko AA; Group Mechanisms of DNA Repair and Carcinogenesis, Equipe Labellisée LIGUE 2016, CNRS UMR9019, Gustave Roussy Cancer Campus, Université Paris-Saclay, F-94805 Villejuif, France.
Saparbaev M; Group Mechanisms of DNA Repair and Carcinogenesis, Equipe Labellisée LIGUE 2016, CNRS UMR9019, Gustave Roussy Cancer Campus, Université Paris-Saclay, F-94805 Villejuif, France.
Fedorova OS; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Kuznetsov NA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 18; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Cleavage*
DNA Damage*
DNA-(Apurinic or Apyrimidinic Site) Lyase/*chemistry
DNA-(Apurinic or Apyrimidinic Site) Lyase/*metabolism
Nucleotides/*metabolism
Binding Sites ; Catalytic Domain ; DNA Repair ; Escherichia coli ; Humans ; Kinetics ; Molecular Dynamics Simulation ; Nucleic Acid Conformation ; Nucleotides/chemistry ; Protein Conformation ; Substrate Specificity
Czasopismo naukowe
Tytuł :
A Novel Intronic Splice-Site Mutation of the CYP11A1 Gene Linked to Adrenal Insufficiency with 46,XY Disorder of Sex Development.
Autorzy :
Matusik P; Department of Pediatrics and Pediatric Endocrinology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-752 Katowice, Poland.
Gach A; Department of Genetics, Polish Mother's Memorial Hospital Research Institute, 93-338 Lodz, Poland.
Zajdel-Cwynar O; Upper-Silesian Child's Health Centre, 40-752 Katowice, Poland.
Pinkier I; Department of Genetics, Polish Mother's Memorial Hospital Research Institute, 93-338 Lodz, Poland.
Kudela G; Department of Pediatric Surgery and Urology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-752 Katowice, Poland.
Gawlik A; Department of Pediatrics and Pediatric Endocrinology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-752 Katowice, Poland.
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Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2021 Jul 05; Vol. 18 (13). Date of Electronic Publication: 2021 Jul 05.
Typ publikacji :
Case Reports; Research Support, Non-U.S. Gov't
MeSH Terms :
Adrenal Insufficiency*/genetics
Cholesterol Side-Chain Cleavage Enzyme*/genetics
Disorder of Sex Development, 46,XY/*genetics
Adolescent ; Female ; Humans ; Hydrocortisone ; Introns ; Mutation
Raport
Tytuł :
Droplet and fibril formation of the functional amyloid Orb2.
Autorzy :
Ashami K; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Falk AS; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Hurd C; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Garg S; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Cervantes SA; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Rawat A; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Siemer AB; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, USA. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2021 Jul; Vol. 297 (1), pp. 100804. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Amyloid/*metabolism
Drosophila Proteins/*metabolism
Drosophila melanogaster/*metabolism
Transcription Factors/*metabolism
mRNA Cleavage and Polyadenylation Factors/*metabolism
Amino Acid Sequence ; Amyloid/ultrastructure ; Animals ; Benzothiazoles/metabolism ; Carbon Isotopes ; Drosophila Proteins/chemistry ; Drosophila melanogaster/ultrastructure ; Fluorescence ; Osmolar Concentration ; Protein Domains ; Transcription Factors/chemistry ; mRNA Cleavage and Polyadenylation Factors/chemistry
Czasopismo naukowe
Tytuł :
Analysis of NHEJ-Based DNA Repair after CRISPR-Mediated DNA Cleavage.
Autorzy :
Song B; Department of Chemistry, Hanyang University, Seoul 04763, Korea.; Research Institute for Convergence of Basic Sciences, Hanyang University, Seoul 04763, Korea.
Yang S; Department of Chemistry, Hanyang University, Seoul 04763, Korea.
Hwang GH; Department of Chemistry, Hanyang University, Seoul 04763, Korea.
Yu J; Department of Chemistry, Hanyang University, Seoul 04763, Korea.; Research Institute for Convergence of Basic Sciences, Hanyang University, Seoul 04763, Korea.
Bae S; Department of Chemistry, Hanyang University, Seoul 04763, Korea.; Research Institute for Convergence of Basic Sciences, Hanyang University, Seoul 04763, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 15; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 15.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Cleavage*
Clustered Regularly Interspaced Short Palindromic Repeats/*genetics
DNA End-Joining Repair/*genetics
Base Sequence ; DNA/metabolism ; HEK293 Cells ; HeLa Cells ; Humans ; Mutation/genetics ; Oligonucleotides/metabolism ; RNA, Guide/genetics ; Sequence Deletion/genetics
Czasopismo naukowe
Tytuł :
Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1.
Autorzy :
Zhang B; The Key Laboratory of Innate Immune Biology of Fujian Province, Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Luo D; The Key Laboratory of Innate Immune Biology of Fujian Province, Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Li Y; The Key Laboratory of Innate Immune Biology of Fujian Province, Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Perčulija V; The Key Laboratory of Innate Immune Biology of Fujian Province, Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Chen J; The Key Laboratory of Innate Immune Biology of Fujian Province, Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Lin J; The Key Laboratory of Innate Immune Biology of Fujian Province, Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Ye Y; The Key Laboratory of Innate Immune Biology of Fujian Province, Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Ouyang S; The Key Laboratory of Innate Immune Biology of Fujian Province, Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Jun 09; Vol. 12 (1), pp. 3476. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Cleavage*
R-Loop Structures*
CRISPR-Associated Proteins/*chemistry
Endonucleases/*chemistry
Base Pairing ; CRISPR-Associated Proteins/genetics ; CRISPR-Associated Proteins/metabolism ; Catalytic Domain ; DNA/chemistry ; DNA/metabolism ; Endonucleases/genetics ; Endonucleases/metabolism ; Enzyme Activation ; Magnesium/chemistry ; Models, Biological ; Models, Molecular ; Protein Conformation ; Protein Structure, Tertiary ; RNA, Guide/chemistry ; RNA, Guide/metabolism ; Temperature
Czasopismo naukowe
Tytuł :
Correlation Networks Provide New Insights into the Architecture of Testicular Steroid Pathways in Pigs.
Autorzy :
Robic A; GenPhySE, Université de Toulouse, INRAE, ENVT, 31326 Castanet Tolosan, France.
Faraut T; GenPhySE, Université de Toulouse, INRAE, ENVT, 31326 Castanet Tolosan, France.
Feve K; GenPhySE, Université de Toulouse, INRAE, ENVT, 31326 Castanet Tolosan, France.
Djebali S; GenPhySE, Université de Toulouse, INRAE, ENVT, 31326 Castanet Tolosan, France.; Institut National de Recherche en Santé Digestive (IRSD), Université de Toulouse, INSERM, INRAE, ENVT, Université Paul Sabatier (UPS), 31024 Toulouse, France.
Prunier A; PEGASE, INRAE, Institut Agro, 35590 Saint Gilles, France.
Larzul C; GenPhySE, Université de Toulouse, INRAE, ENVT, 31326 Castanet Tolosan, France.
Liaubet L; GenPhySE, Université de Toulouse, INRAE, ENVT, 31326 Castanet Tolosan, France.
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Źródło :
Genes [Genes (Basel)] 2021 Apr 09; Vol. 12 (4). Date of Electronic Publication: 2021 Apr 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Regulatory Networks*
Signal Transduction*
17-Hydroxysteroid Dehydrogenases/*metabolism
Cholesterol Side-Chain Cleavage Enzyme/*metabolism
Testis/*metabolism
Testosterone/*metabolism
17-Hydroxysteroid Dehydrogenases/genetics ; Animals ; Cholesterol Side-Chain Cleavage Enzyme/genetics ; Male ; Swine
Czasopismo naukowe
Tytuł :
Characterization and Optimization of a Deoxyribozyme with a Short Left Binding Arm.
Autorzy :
Wang Y; Department of Biomedical Engineering, College of Engineering and Applied Sciences, Nanjing University, Nanjing, Jiangsu, China.
Yu H; Department of Biomedical Engineering, College of Engineering and Applied Sciences, Nanjing University, Nanjing, Jiangsu, China. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2167, pp. 79-89.
Typ publikacji :
Journal Article
MeSH Terms :
Nucleic Acid Conformation*
DNA, Catalytic/*chemistry
DNA, Catalytic/*metabolism
Electrophoresis, Polyacrylamide Gel/*methods
Enzyme Assays/*methods
RNA Cleavage/*drug effects
Base Sequence ; Catalysis ; Catalytic Domain ; DNA, Catalytic/genetics ; Hydrogen-Ion Concentration ; In Vitro Techniques ; Ions/chemistry ; Kinetics ; Metals/chemistry ; Models, Molecular ; Oligonucleotides/chemistry ; Oligonucleotides/genetics ; RNA Cleavage/genetics ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Site-Selective Artificial Ribonucleases: Renaissance of Oligonucleotide Conjugates for Irreversible Cleavage of RNA Sequences.
Autorzy :
Staroseletz Y; Laboratory of Nucleic Acids Biochemistry, Institute of Chemical Biology and Fundamental Medicine SB RAS, Lavrentiev's Ave. 8, 630090 Novosibirsk, Russia.
Gaponova S; Laboratory of Nucleic Acids Biochemistry, Institute of Chemical Biology and Fundamental Medicine SB RAS, Lavrentiev's Ave. 8, 630090 Novosibirsk, Russia.
Patutina O; Laboratory of Nucleic Acids Biochemistry, Institute of Chemical Biology and Fundamental Medicine SB RAS, Lavrentiev's Ave. 8, 630090 Novosibirsk, Russia.
Bichenkova E; School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Oxford Rd., Manchester M13 9PT, UK.
Amirloo B; School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Oxford Rd., Manchester M13 9PT, UK.
Heyman T; School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Oxford Rd., Manchester M13 9PT, UK.
Chiglintseva D; Laboratory of Nucleic Acids Biochemistry, Institute of Chemical Biology and Fundamental Medicine SB RAS, Lavrentiev's Ave. 8, 630090 Novosibirsk, Russia.
Zenkova M; Laboratory of Nucleic Acids Biochemistry, Institute of Chemical Biology and Fundamental Medicine SB RAS, Lavrentiev's Ave. 8, 630090 Novosibirsk, Russia.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Mar 19; Vol. 26 (6). Date of Electronic Publication: 2021 Mar 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Base Sequence*
RNA Cleavage*
DNA, Catalytic/*chemistry
Oligonucleotides/*chemistry
RNA/*chemistry
Ribonucleases/*chemistry
Czasopismo naukowe
Tytuł :
Understanding RNA Binding by the Nonclassical Zinc Finger Protein CPSF30, a Key Factor in Polyadenylation during Pre-mRNA Processing.
Autorzy :
Pritts JD; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201-1180, United States.
Oluyadi AA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201-1180, United States.
Huang W; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201-1180, United States.
Shimberg GD; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201-1180, United States.
Kane MA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201-1180, United States.
Wilks A; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201-1180, United States.
Michel SLJ; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201-1180, United States.
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Źródło :
Biochemistry [Biochemistry] 2021 Mar 16; Vol. 60 (10), pp. 780-790. Date of Electronic Publication: 2021 Feb 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Polyadenylation*
Cleavage And Polyadenylation Specificity Factor/*metabolism
Poly U/*metabolism
RNA Precursors/*metabolism
RNA, Messenger/*metabolism
Animals ; Binding Sites ; Cattle ; Cleavage And Polyadenylation Specificity Factor/chemistry ; Cleavage And Polyadenylation Specificity Factor/genetics ; Protein Binding ; RNA Precursors/genetics ; RNA, Messenger/chemistry ; RNA, Messenger/genetics ; Zinc Fingers
Czasopismo naukowe
Tytuł :
Integrator is a genome-wide attenuator of non-productive transcription.
Autorzy :
Lykke-Andersen S; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark. Electronic address: .
Žumer K; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Molska EŠ; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Rouvière JO; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Wu G; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Demel C; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Schwalb B; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Schmid M; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Cramer P; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany. Electronic address: .
Jensen TH; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Feb 04; Vol. 81 (3), pp. 514-529.e6. Date of Electronic Publication: 2020 Dec 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Transcription Termination, Genetic*
Cleavage And Polyadenylation Specificity Factor/*metabolism
DNA-Binding Proteins/*metabolism
RNA Polymerase II/*metabolism
RNA, Small Nuclear/*biosynthesis
Cleavage And Polyadenylation Specificity Factor/genetics ; DNA-Binding Proteins/genetics ; HeLa Cells ; Humans ; Polyadenylation ; Promoter Regions, Genetic ; RNA Polymerase II/genetics ; RNA, Small Nuclear/genetics
Czasopismo naukowe
Tytuł :
Advances of functional consequences and regulation mechanisms of alternative cleavage and polyadenylation.
Autorzy :
Xu HD; Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Harbin 150030, China.; Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, Harbin 150030, China.; College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.
Ning BL; Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Harbin 150030, China.; Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, Harbin 150030, China.; College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.
Mu F; Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Harbin 150030, China.; Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, Harbin 150030, China.; College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.
Li H; Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Harbin 150030, China.; Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, Harbin 150030, China.; College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.
Wang N; Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Harbin 150030, China.; Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, Harbin 150030, China.; College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.
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Źródło :
Yi chuan = Hereditas [Yi Chuan] 2021 Jan 20; Vol. 43 (1), pp. 4-15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA Cleavage*
Gene Expression Regulation*
Polyadenylation*
3' Untranslated Regions ; Animals ; Plants ; RNA Stability ; Yeasts
Czasopismo naukowe
Tytuł :
Comment on "Photochemical Activities of N-Nitroso Carboxamides and Sulfoximides and Their Application to DNA Cleavage".
Autorzy :
Korth HG; Institut für Organische Chemie, Universität Duisburg-Essen, Universitätsstr. 7, 45117, Essen, Germany.
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Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 Jan 18; Vol. 27 (4), pp. 1473-1475. Date of Electronic Publication: 2020 Dec 23.
Typ publikacji :
Letter
MeSH Terms :
DNA Cleavage*
Nitric Oxide*
Nitrogen Oxides/*chemistry
Free Radicals
Opinia redakcyjna
Tytuł :
Estrogen promotes increased breast cancer cell proliferation and migration through downregulation of CPEB1 expression.
Autorzy :
Sovijit W; Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan.
Sovijit W; Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan.
Ishii Y; Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan.
Kambe J; Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan.
Fujita T; Department of Breast Surgery, Tokyo Medical University Ibaraki Medical Center, 3-20-1 Chuo, Ami-cho, Ibaraki, 300-0395, Japan.
Watanabe G; Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan.
Yamaguchi H; Cancer Research Center, Qatar Biomedical Research Institute, Hamad Bin Khalifa University, Qatar Foundation, P.O Box 34110, Doha, Qatar.
Nagaoka K; Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Jan 01; Vol. 534, pp. 871-876. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Breast Neoplasms/*genetics
Estrogens/*metabolism
Transcription Factors/*genetics
mRNA Cleavage and Polyadenylation Factors/*genetics
Adult ; Aged ; Aged, 80 and over ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cell Movement ; Cell Proliferation ; Down-Regulation ; Female ; Humans ; MCF-7 Cells ; Middle Aged ; Transcription Factors/analysis ; Transcription Factors/metabolism ; mRNA Cleavage and Polyadenylation Factors/analysis ; mRNA Cleavage and Polyadenylation Factors/metabolism
Czasopismo naukowe
Tytuł :
Molecular mechanism for the interaction between human CPSF30 and hFip1.
Autorzy :
Hamilton K; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
Tong L; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
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Źródło :
Genes & development [Genes Dev] 2020 Dec 01; Vol. 34 (23-24), pp. 1753-1761. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Models, Molecular*
Cleavage And Polyadenylation Specificity Factor/*chemistry
Cleavage And Polyadenylation Specificity Factor/*metabolism
mRNA Cleavage and Polyadenylation Factors/*chemistry
Binding Sites ; Cleavage And Polyadenylation Specificity Factor/genetics ; Escherichia coli/genetics ; Humans ; Mutation ; Protein Binding ; Protein Structure, Quaternary ; Zinc Fingers/physiology ; mRNA Cleavage and Polyadenylation Factors/genetics ; mRNA Cleavage and Polyadenylation Factors/metabolism
Czasopismo naukowe
Tytuł :
Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery.
Autorzy :
Zhang Y; Laboratory of Molecular Electron Microscopy, Rockefeller University, New York, NY 10065, USA.
Sun Y; Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
Shi Y; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA.
Walz T; Laboratory of Molecular Electron Microscopy, Rockefeller University, New York, NY 10065, USA. Electronic address: .
Tong L; Department of Biological Sciences, Columbia University, New York, NY 10027, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Feb 20; Vol. 77 (4), pp. 800-809.e6. Date of Electronic Publication: 2019 Dec 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cleavage And Polyadenylation Specificity Factor/*chemistry
Cleavage And Polyadenylation Specificity Factor/genetics ; Cleavage Stimulation Factor/chemistry ; Cryoelectron Microscopy ; Humans ; Models, Molecular ; Mutation ; RNA 3' End Processing ; RNA Precursors/metabolism ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
Structure-function analysis of fission yeast cleavage and polyadenylation factor (CPF) subunit Ppn1 and its interactions with Dis2 and Swd22.
Autorzy :
Benjamin B; Molecular Biology Program, Sloan-Kettering Institute, New York, New York, United States of America.; Gerstner Sloan Kettering Graduate School of Biomedical Sciences, New York, New York, United States of America.
Sanchez AM; Molecular Biology Program, Sloan-Kettering Institute, New York, New York, United States of America.; Gerstner Sloan Kettering Graduate School of Biomedical Sciences, New York, New York, United States of America.
Garg A; Molecular Biology Program, Sloan-Kettering Institute, New York, New York, United States of America.
Schwer B; Dept. of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.
Shuman S; Molecular Biology Program, Sloan-Kettering Institute, New York, New York, United States of America.
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Źródło :
PLoS genetics [PLoS Genet] 2021 Mar 12; Vol. 17 (3), pp. e1009452. Date of Electronic Publication: 2021 Mar 12 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Protein Interaction Domains and Motifs*
Acid Anhydride Hydrolases/*metabolism
Protein Phosphatase 1/*metabolism
Schizosaccharomyces/*physiology
mRNA Cleavage and Polyadenylation Factors/*metabolism
Alleles ; Amino Acid Sequence ; Computational Biology/methods ; Gene Expression Profiling ; Gene Expression Regulation, Fungal ; Models, Biological ; Mutation ; Phenotype ; Phosphorylation ; Transcription, Genetic ; Transcriptome ; mRNA Cleavage and Polyadenylation Factors/chemistry
Czasopismo naukowe
Tytuł :
Divalent Ion-Induced Switch in DNA Cleavage of KpnI Endonuclease Probed through Surface-Enhanced Raman Spectroscopy.
Autorzy :
Aggarwal S; Light Scattering Lab, Chemistry and Physics of Materials Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore 560064, India.
Mondal S; Light Scattering Lab, Chemistry and Physics of Materials Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore 560064, India.
Siddhanta S; Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India.
Bharat E; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.
Nagamalleswari E; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.
Nagaraja V; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.; Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore 560064, India.
Narayana C; Light Scattering Lab, Chemistry and Physics of Materials Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore 560064, India.
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Źródło :
The journal of physical chemistry. B [J Phys Chem B] 2021 Mar 11; Vol. 125 (9), pp. 2241-2250. Date of Electronic Publication: 2021 Mar 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Cleavage*
Spectrum Analysis, Raman*
Cations, Divalent ; Deoxyribonucleases, Type II Site-Specific/genetics ; Ions
Czasopismo naukowe
Tytuł :
Mechanism of DNA cleavage by the endonuclease SauUSI: a major barrier to horizontal gene transfer and antibiotic resistance in Staphylococcus aureus.
Autorzy :
Tumuluri VS; Department of Biology, Indian Institute of Science Education and Research, Pune 411008, India.
Rajgor V; Department of Biology, Indian Institute of Science Education and Research, Pune 411008, India.
Xu SY; New England Biolabs Inc., Research Department, Ipswich, MA 01938, USA.
Chouhan OP; Department of Biology, Indian Institute of Science Education and Research, Pune 411008, India.
Saikrishnan K; Department of Biology, Indian Institute of Science Education and Research, Pune 411008, India.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Feb 26; Vol. 49 (4), pp. 2161-2178.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Cleavage*
Endodeoxyribonucleases/*chemistry
Endodeoxyribonucleases/*metabolism
Staphylococcus aureus/*enzymology
Adenosine Triphosphatases/chemistry ; Adenosine Triphosphatases/metabolism ; DNA/chemistry ; Drug Resistance, Bacterial ; Gene Transfer, Horizontal ; Models, Molecular ; Protein Multimerization ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/genetics
Czasopismo naukowe
Tytuł :
Forty Years after the Discovery of Its Nucleolytic Activity: [Cu(phen) 2 ] Shows Unattended DNA Cleavage Activity upon Fluorination.
Autorzy :
Lüdtke C; Institut für Chemie und Biochemie, Freie Universität Berlin, Fabeckstr. 34/36, 14195, Berlin, Germany.
Sobottka S; Institut für Chemie und Biochemie, Freie Universität Berlin, Fabeckstr. 34/36, 14195, Berlin, Germany.
Heinrich J; Institut für Chemie, Otto-von-Guericke-Universität Magdeburg, Universitätsplatz 2, 39106, Magdeburg, Germany.
Liebing P; Institut für Chemie, Otto-von-Guericke-Universität Magdeburg, Universitätsplatz 2, 39106, Magdeburg, Germany.
Wedepohl S; Institut für Chemie und Biochemie, Freie Universität Berlin, Arnimallee 22, 14195, Berlin, Germany.
Sarkar B; Institut für Chemie und Biochemie, Freie Universität Berlin, Fabeckstr. 34/36, 14195, Berlin, Germany.; Institut für Anorganische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569, Stuttgart, Germany.
Kulak N; Institut für Chemie und Biochemie, Freie Universität Berlin, Fabeckstr. 34/36, 14195, Berlin, Germany.; Institut für Chemie, Otto-von-Guericke-Universität Magdeburg, Universitätsplatz 2, 39106, Magdeburg, Germany.
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Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 Feb 15; Vol. 27 (10), pp. 3273-3277. Date of Electronic Publication: 2021 Jan 22.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Cleavage*
Halogenation*
Copper ; Crystallography, X-Ray ; DNA/metabolism ; Ligands ; Phenanthrolines
Czasopismo naukowe

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