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Tytuł:
Downregulation of CPSF6 leads to global mRNA 3' UTR shortening and enhanced antiviral immune responses.
Autorzy:
Ge Y; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
Huang J; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
Chen R; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
Fu Y; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.
Ling T; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
Ou X; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.
Rong X; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
Cheng Y; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
Lin Y; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
Zhou F; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.
Lu C; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China.; State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China.
Yuan S; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
Xu A; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Feb 28; Vol. 20 (2), pp. e1012061. Date of Electronic Publication: 2024 Feb 28 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
mRNA Cleavage and Polyadenylation Factors*/genetics
mRNA Cleavage and Polyadenylation Factors*/metabolism
Polyadenylation*
Virus Diseases*/genetics
Humans ; 3' Untranslated Regions/genetics ; Down-Regulation ; Immunity/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Mice ; Animals
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hydrolytic endonucleolytic ribozyme (HYER) is programmable for sequence-specific DNA cleavage.
Autorzy:
Liu ZX; Beijing Advanced Innovation Center for Structural Biology, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Zhang S; Beijing Advanced Innovation Center for Structural Biology, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Zhu HZ; Beijing Advanced Innovation Center for Structural Biology, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Chen ZH; Beijing Advanced Innovation Center for Structural Biology, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Yang Y; Beijing Advanced Innovation Center for Structural Biology, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Li LQ; Beijing Advanced Innovation Center for Structural Biology, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Lei Y; New Cornerstone Science Laboratory, Center for Genome Editing, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.; College of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing, China.
Liu Y; Beijing Advanced Innovation Center for Structural Biology, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Li DY; Beijing Advanced Innovation Center for Structural Biology, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Sun A; Beijing Advanced Innovation Center for Structural Biology, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Li CP; Beijing Advanced Innovation Center for Structural Biology, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Tan SQ; Beijing Advanced Innovation Center for Structural Biology, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Wang GL; Beijing Advanced Innovation Center for Structural Biology, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Shen JY; Beijing Advanced Innovation Center for Structural Biology, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Jin S; New Cornerstone Science Laboratory, Center for Genome Editing, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Gao C; New Cornerstone Science Laboratory, Center for Genome Editing, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.; College of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing, China.
Liu JG; Beijing Advanced Innovation Center for Structural Biology, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Feb 02; Vol. 383 (6682), pp. eadh4859. Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Cleavage*
Endonucleases*/chemistry
Endonucleases*/genetics
RNA, Catalytic*/chemistry
RNA, Catalytic*/genetics
Animals ; Cryoelectron Microscopy ; Hydrolysis ; Introns ; Nucleic Acid Conformation ; RNA Splicing
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Differential tissue expression of sex steroid-synthesizing enzyme CYP11A1 in male Tibetan sheep ( Ovis aries ).
Autorzy:
Wang H; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
Wang X; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
Li T; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
An X; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
Chen N; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
Shi H; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
Su M; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
Ma K; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
Hao Z; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
Duan X; Nongfayuan (Zhejiang) Agricultural Development Co., Ltd., Huzhou, Zhejiang, China.
Ma Y; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.; Sheep Breeding Biotechnology Engineering Laboratory of Gansu Province, Minqin, China.
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Źródło:
Animal biotechnology [Anim Biotechnol] 2023 Dec; Vol. 34 (7), pp. 2900-2909. Date of Electronic Publication: 2022 Sep 28.
Typ publikacji:
Journal Article
MeSH Terms:
Sheep, Domestic*
Cholesterol Side-Chain Cleavage Enzyme*/genetics
Cholesterol Side-Chain Cleavage Enzyme*/metabolism
Sheep/genetics ; Male ; Animals ; Tibet ; Testis/metabolism ; Steroids/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Optimal number of high-quality cleavage-stage embryos for extended culture to blastocyst-stage for transfer in women 38 years and older.
Autorzy:
Xue X; The ART Center, Northwest Women's and Children's Hospital, Xi'an, PR China.
Li W; The ART Center, Northwest Women's and Children's Hospital, Xi'an, PR China.
Li M; The ART Center, Northwest Women's and Children's Hospital, Xi'an, PR China.
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Źródło:
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2023 Dec; Vol. 39 (1), pp. 2181642. Date of Electronic Publication: 2023 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
Pregnancy, Multiple*
Cleavage Stage, Ovum*
Pregnancy ; Female ; Humans ; Adult ; Pregnancy Rate ; Retrospective Studies ; Blastocyst
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Combinatorial Code for CPEB-Mediated c-myc Repression.
Autorzy:
Ogami K; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.; Division of Molecular Oncology, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
Ogawa K; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
Sanpei S; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
Ichikawa F; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
Udagawa T; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
Hoshino SI; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
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Źródło:
Cells [Cells] 2023 Oct 06; Vol. 12 (19). Date of Electronic Publication: 2023 Oct 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
mRNA Cleavage and Polyadenylation Factors*/metabolism
Oocytes*/metabolism
RNA/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA-Binding Proteins/metabolism ; Transcription Factors/metabolism ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pregnenolone and progesterone production from natural sterols using recombinant strain of Mycolicibacterium smegmatis mc  155 expressing mammalian steroidogenesis system.
Autorzy:
Karpov M; G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, RAS, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', Pushchino, 142290, Russia. .
Strizhov N; G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, RAS, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', Pushchino, 142290, Russia.
Novikova L; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Leninskie Gory 1/40, Moscow, 119234, Russia.
Lobastova T; G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, RAS, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', Pushchino, 142290, Russia.
Khomutov S; G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, RAS, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', Pushchino, 142290, Russia.
Shutov A; G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, RAS, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', Pushchino, 142290, Russia.
Kazantsev A; Chemistry Department, Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119991, Russia.
Donova M; G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, RAS, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', Pushchino, 142290, Russia. .
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Źródło:
Microbial cell factories [Microb Cell Fact] 2024 Apr 09; Vol. 23 (1), pp. 105. Date of Electronic Publication: 2024 Apr 09.
Typ publikacji:
Journal Article
MeSH Terms:
Progesterone*
Phytosterols*
Cattle ; Animals ; Pregnenolone/metabolism ; Sterols ; Steroids ; Cholesterol/metabolism ; Cholesterol Side-Chain Cleavage Enzyme/genetics ; Cholesterol Side-Chain Cleavage Enzyme/metabolism ; Mammals/metabolism ; Ethers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Csx28 is a membrane pore that enhances CRISPR-Cas13b-dependent antiphage defense.
Autorzy:
VanderWal AR; Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA.; Center for RNA Biology, University of Rochester, Rochester, NY, USA.
Park JU; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
Polevoda B; Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA.; Center for RNA Biology, University of Rochester, Rochester, NY, USA.
Nicosia JK; Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA.; Center for RNA Biology, University of Rochester, Rochester, NY, USA.
Molina Vargas AM; Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA.; Center for RNA Biology, University of Rochester, Rochester, NY, USA.
Kellogg EH; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
O'Connell MR; Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA.; Center for RNA Biology, University of Rochester, Rochester, NY, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Apr 28; Vol. 380 (6643), pp. 410-415. Date of Electronic Publication: 2023 Apr 27.
Typ publikacji:
Journal Article
MeSH Terms:
CRISPR-Cas Systems*
RNA, Viral*/metabolism
Bacterial Proteins*/chemistry
Bacterial Proteins*/metabolism
Endodeoxyribonucleases*/chemistry
Endodeoxyribonucleases*/metabolism
CRISPR-Associated Proteins*/chemistry
CRISPR-Associated Proteins*/metabolism
RNA Cleavage*
Bacteriophages*/metabolism
Prevotella*/enzymology
Prevotella*/virology
Cryoelectron Microscopy ; Membrane Proteins/metabolism ; Bacteriophage lambda/metabolism ; Escherichia coli/enzymology ; Escherichia coli/virology
SCR Organism:
Prevotella buccae
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pseudomonas aeruginosa Dps (PA0962) Functions in H 2 O 2 Mediated Oxidative Stress Defense and Exhibits In Vitro DNA Cleaving Activity.
Autorzy:
Rajapaksha N; Department of Chemistry, Louisiana State University, 232 Choppin Hall, Baton Rouge, LA 70803, USA.
Soldano A; Department of Chemistry, Louisiana State University, 232 Choppin Hall, Baton Rouge, LA 70803, USA.
Yao H; Department of Chemistry, Louisiana State University, 232 Choppin Hall, Baton Rouge, LA 70803, USA.
Donnarumma F; Department of Chemistry, Louisiana State University, 232 Choppin Hall, Baton Rouge, LA 70803, USA.
Kashipathy MM; Protein Structure and X-ray Crystallography Laboratory, University of Kansas, 2034 Becker Dr., Lawrence, KS 66047, USA.
Seibold S; Protein Structure and X-ray Crystallography Laboratory, University of Kansas, 2034 Becker Dr., Lawrence, KS 66047, USA.
Battaile KP; NYX, New York Structural Biology Center, Upton, NY 11973, USA.
Lovell S; Protein Structure and X-ray Crystallography Laboratory, University of Kansas, 2034 Becker Dr., Lawrence, KS 66047, USA.
Rivera M; Department of Chemistry, Louisiana State University, 232 Choppin Hall, Baton Rouge, LA 70803, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 28; Vol. 24 (5). Date of Electronic Publication: 2023 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Bacterial Proteins*/metabolism
DNA Cleavage*
Hydrogen Peroxide*/metabolism
Oxidative Stress*
Pseudomonas aeruginosa*/genetics
Pseudomonas aeruginosa*/metabolism
DNA-Binding Proteins*/metabolism
Cations, Divalent ; DNA/metabolism ; Iron/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of Bushen Yiyuan recipe on testosterone synthesis in Leydig cells of rats with exercise-induced low serum testosterone levels.
Autorzy:
Wang Y; Institute of Physical Education, Hunan Normal University, Changsha, China.; Hunan Sports Vocational College, Changsha, China.
Peng X; Institute of Physical Education, Hunan Normal University, Changsha, China.
Zhou Z; Hunan Sports Vocational College, Changsha, China.
Tang C; Institute of Physical Education, Hunan Normal University, Changsha, China.
Liu W; Institute of Physical Education, Hunan Normal University, Changsha, China.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2022 Dec; Vol. 60 (1), pp. 1670-1678.
Typ publikacji:
Journal Article
MeSH Terms:
Cholesterol Side-Chain Cleavage Enzyme*/genetics
Cholesterol Side-Chain Cleavage Enzyme*/metabolism
Leydig Cells*/metabolism
Animals ; Male ; Rats ; Rats, Sprague-Dawley ; Testosterone
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Structure- and Content-Dependent Efficiency of Cas9-Assisted DNA Cleavage in Genome-Editing Systems.
Autorzy:
Baranova SV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia.
Zhdanova PV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia.
Lomzov AA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia.; Department of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia.
Koval VV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia.; Department of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia.
Chernonosov AA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 11; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 11.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Cleavage*
CRISPR-Cas Systems*
Endonucleases/metabolism ; Gene Editing/methods ; DNA/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Uncovering the functional diversity of rare CRISPR-Cas systems with deep terascale clustering.
Autorzy:
Altae-Tran H; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research at MIT, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Kannan S; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research at MIT, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Suberski AJ; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research at MIT, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Mears KS; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research at MIT, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Demircioglu FE; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research at MIT, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Moeller L; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research at MIT, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Kocalar S; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research at MIT, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Oshiro R; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research at MIT, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Makarova KS; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
Macrae RK; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research at MIT, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Koonin EV; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
Zhang F; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research at MIT, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Nov 24; Vol. 382 (6673), pp. eadi1910. Date of Electronic Publication: 2023 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
CRISPR-Cas Systems*/genetics
Gene Editing*
CRISPR-Associated Proteins*/chemistry
CRISPR-Associated Proteins*/classification
CRISPR-Associated Proteins*/genetics
Data Mining*/methods
Humans ; HEK293 Cells ; Cluster Analysis ; Algorithms ; DNA Cleavage ; RNA, Guide, CRISPR-Cas Systems ; Datasets as Topic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Melatonin Inhibits Testosterone Synthesis in Rooster Leydig Cells by Targeting CXCL14 through miR-7481-3p.
Autorzy:
Xu H; Key Lab of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.; Jilin Province Engineering Laboratory for Ruminant Reproductive Biotechnology and Healthy Production, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Pu J; Key Lab of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.; Jilin Province Engineering Laboratory for Ruminant Reproductive Biotechnology and Healthy Production, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Teng Y; Key Lab of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.; Jilin Province Engineering Laboratory for Ruminant Reproductive Biotechnology and Healthy Production, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Zhu Q; Key Lab of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.; Jilin Province Engineering Laboratory for Ruminant Reproductive Biotechnology and Healthy Production, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Guo L; Key Lab of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.; Jilin Province Engineering Laboratory for Ruminant Reproductive Biotechnology and Healthy Production, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Zhao J; Key Lab of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.; Jilin Province Engineering Laboratory for Ruminant Reproductive Biotechnology and Healthy Production, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Ding H; Key Lab of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.; Jilin Province Engineering Laboratory for Ruminant Reproductive Biotechnology and Healthy Production, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Fang Y; Key Lab of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.; Jilin Province Engineering Laboratory for Ruminant Reproductive Biotechnology and Healthy Production, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Ma X; Key Lab of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.; Jilin Province Engineering Laboratory for Ruminant Reproductive Biotechnology and Healthy Production, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Liu H; Key Lab of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.; Jilin Province Engineering Laboratory for Ruminant Reproductive Biotechnology and Healthy Production, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Guo J; Key Lab of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.; Jilin Province Engineering Laboratory for Ruminant Reproductive Biotechnology and Healthy Production, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Lu W; Key Lab of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.; Jilin Province Engineering Laboratory for Ruminant Reproductive Biotechnology and Healthy Production, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Wang J; Key Lab of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.; Jilin Province Engineering Laboratory for Ruminant Reproductive Biotechnology and Healthy Production, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 21; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 21.
Typ publikacji:
Journal Article
MeSH Terms:
Leydig Cells*/metabolism
Melatonin*/pharmacology
Melatonin*/metabolism
MicroRNAs*/metabolism
Testosterone*/metabolism
Animals ; Male ; Chickens/genetics ; Cholesterol Side-Chain Cleavage Enzyme/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The A'-helix of CYP11A1 remodels mitochondrial cristae.
Autorzy:
Rosal KG; Molecular Cell Biology, Taiwan International Graduate Program, Academia Sinica and Graduate Institute of Life Science, National Defense Medical Center, Taipei, 115, Taiwan.; Institute of Molecular Biology, Academia Sinica, Taipei, 115, Taiwan.
Chen WY; Institute of Biochemistry and Molecular Biology, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan.
Chung BC; Molecular Cell Biology, Taiwan International Graduate Program, Academia Sinica and Graduate Institute of Life Science, National Defense Medical Center, Taipei, 115, Taiwan. .; Institute of Molecular Biology, Academia Sinica, Taipei, 115, Taiwan. .; Graduate Institute of Biomedical Sciences, Neuroscience and Brain Disease Center, China Medical University, Taichung, 404, Taiwan. .
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Źródło:
Journal of biomedical science [J Biomed Sci] 2022 Aug 18; Vol. 29 (1), pp. 61. Date of Electronic Publication: 2022 Aug 18.
Typ publikacji:
Journal Article
MeSH Terms:
Cholesterol Side-Chain Cleavage Enzyme*/analysis
Cholesterol Side-Chain Cleavage Enzyme*/genetics
Cholesterol Side-Chain Cleavage Enzyme*/metabolism
Mitochondrial Membranes*/metabolism
Mitochondria/genetics ; Mitochondria/metabolism ; Mitochondrial Proteins/genetics ; Steroids/analysis ; Steroids/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Di-n-Butyl Phthalate and Its Monoester Metabolite Impairs Steroid Hormone Biosynthesis in Human Cells: Mechanistic In Vitro Studies.
Autorzy:
Källsten L; Science for Life Laboratory, Department of Environmental Science, Stockholm University, 114 18 Stockholm, Sweden.
Pierozan P; Science for Life Laboratory, Department of Environmental Science, Stockholm University, 114 18 Stockholm, Sweden.
Martin JW; Science for Life Laboratory, Department of Environmental Science, Stockholm University, 114 18 Stockholm, Sweden.
Karlsson O; Science for Life Laboratory, Department of Environmental Science, Stockholm University, 114 18 Stockholm, Sweden.
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Źródło:
Cells [Cells] 2022 Sep 27; Vol. 11 (19). Date of Electronic Publication: 2022 Sep 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholesterol Side-Chain Cleavage Enzyme*/metabolism
Dibutyl Phthalate*/toxicity
Adenosine Monophosphate ; Androstenedione ; Corticosterone ; Humans ; Hydrocortisone ; Male ; Phthalic Acids ; Progesterone ; Steroid 11-beta-Hydroxylase ; Steroids ; Superoxides ; Testosterone
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Noncanonical DNA Cleavage by BamHI Endonuclease in Laterally Confined DNA Monolayers Is a Step Function of DNA Density and Sequence.
Autorzy:
Adedeji Olulana AF; Department of Physics, PhD School in Nanotechnology, University of Trieste, 34127 Trieste, Italy.; Department of Medical and Biological Sciences, University of Udine, 33100 Udine, Italy.; Regional Centre for Rare Diseases, University Hospital Udine, 33100 Udine, Italy.; School of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT, UK.
Choi D; Department of Biology, Temple University, Philadelphia, PA 19122-6078, USA.
Inverso V; Department of Biology, Temple University, Philadelphia, PA 19122-6078, USA.
Redhu SK; Department of Biology, Temple University, Philadelphia, PA 19122-6078, USA.
Vidonis M; Department of Medical and Biological Sciences, University of Udine, 33100 Udine, Italy.; Department of Chemistry, University of Rome 'Tor Vergata', 00133 Rome, Italy.
Crevatin L; Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.
Nicholson AW; Department of Biology, Temple University, Philadelphia, PA 19122-6078, USA.
Castronovo M; Department of Physics, PhD School in Nanotechnology, University of Trieste, 34127 Trieste, Italy.; Department of Medical and Biological Sciences, University of Udine, 33100 Udine, Italy.; Regional Centre for Rare Diseases, University Hospital Udine, 33100 Udine, Italy.; School of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT, UK.; Department of Biology, Temple University, Philadelphia, PA 19122-6078, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Aug 17; Vol. 27 (16). Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:
Journal Article
MeSH Terms:
DNA*/chemistry
DNA Cleavage*
Base Sequence ; DNA Restriction Enzymes/metabolism ; Deoxyribonuclease BamHI/metabolism ; Substrate Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structural basis for RNA-guided DNA cleavage by IscB-ωRNA and mechanistic comparison with Cas9.
Autorzy:
Schuler G; Department of Molecular Biology and Genetics, Cornell University, 253 Biotechnology Building, Ithaca, NY 14853, USA.
Hu C; Department of Molecular Biology and Genetics, Cornell University, 253 Biotechnology Building, Ithaca, NY 14853, USA.
Ke A; Department of Molecular Biology and Genetics, Cornell University, 253 Biotechnology Building, Ithaca, NY 14853, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Jun 24; Vol. 376 (6600), pp. 1476-1481. Date of Electronic Publication: 2022 May 26.
Typ publikacji:
Journal Article
MeSH Terms:
CRISPR-Associated Protein 9*/chemistry
CRISPR-Associated Protein 9*/genetics
CRISPR-Cas Systems*
DNA Cleavage*
RNA, Guide, CRISPR-Cas Systems*/chemistry
Ribonucleoproteins*/chemistry
Amino Acid Motifs ; Cryoelectron Microscopy ; Nucleic Acid Conformation ; Protein Domains ; RNA, Bacterial/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cleavage-stage human embryo arrest, is it embryo genetic composition or others?
Autorzy:
Orvieto R; Infertility and IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center (Tel Hashomer), 56261, Ramat Gan, Israel. .; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. .; The Tarnesby-Tarnowski Chair for Family Planning and Fertility Regulation, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel. .
Jonish-Grossman A; Danek Gertner Institute of Human Genetics, Sheba Medical Center, 56261, Ramat-Gan, Israel.
Maydan SA; Infertility and IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center (Tel Hashomer), 56261, Ramat Gan, Israel.; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Noach-Hirsh M; Infertility and IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center (Tel Hashomer), 56261, Ramat Gan, Israel.
Dratviman-Storobinsky O; Infertility and IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center (Tel Hashomer), 56261, Ramat Gan, Israel.
Aizer A; Infertility and IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center (Tel Hashomer), 56261, Ramat Gan, Israel.; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
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Źródło:
Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2022 Mar 17; Vol. 20 (1), pp. 52. Date of Electronic Publication: 2022 Mar 17.
Typ publikacji:
Journal Article
MeSH Terms:
Blastocyst/*metabolism
Cleavage Stage, Ovum/*metabolism
Embryo, Mammalian/*metabolism
Embryonic Development/*genetics
Trophoblasts/*metabolism
Adult ; Aneuploidy ; Blastocyst/cytology ; Blastomeres/cytology ; Blastomeres/metabolism ; Cells, Cultured ; Cleavage Stage, Ovum/cytology ; Comparative Genomic Hybridization/methods ; Embryo Transfer ; Embryo, Mammalian/cytology ; Female ; Fertilization in Vitro ; Genetic Testing/methods ; Humans ; Live Birth ; Pregnancy ; Pregnancy Rate ; Trophoblasts/cytology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structural transitions upon guide RNA binding and their importance in Cas12g-mediated RNA cleavage.
Autorzy:
Liu M; Key Laboratory of Microbial Pathogenesis and Interventions-Fujian Province University, the Key Laboratory of Innate Immune Biology of Fujian Province, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of the Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Li Z; Key Laboratory of Microbial Pathogenesis and Interventions-Fujian Province University, the Key Laboratory of Innate Immune Biology of Fujian Province, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of the Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Chen J; Key Laboratory of Microbial Pathogenesis and Interventions-Fujian Province University, the Key Laboratory of Innate Immune Biology of Fujian Province, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of the Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Lin J; Key Laboratory of Microbial Pathogenesis and Interventions-Fujian Province University, the Key Laboratory of Innate Immune Biology of Fujian Province, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of the Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Lu Q; Key Laboratory of Microbial Pathogenesis and Interventions-Fujian Province University, the Key Laboratory of Innate Immune Biology of Fujian Province, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of the Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Ye Y; Key Laboratory of Microbial Pathogenesis and Interventions-Fujian Province University, the Key Laboratory of Innate Immune Biology of Fujian Province, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of the Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Zhang H; Department of Biology, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Zhang B; Key Laboratory of Microbial Pathogenesis and Interventions-Fujian Province University, the Key Laboratory of Innate Immune Biology of Fujian Province, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of the Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Ouyang S; Key Laboratory of Microbial Pathogenesis and Interventions-Fujian Province University, the Key Laboratory of Innate Immune Biology of Fujian Province, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of the Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China.
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Źródło:
PLoS genetics [PLoS Genet] 2023 Sep 20; Vol. 19 (9), pp. e1010930. Date of Electronic Publication: 2023 Sep 20 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA, Guide, CRISPR-Cas Systems*
Endonucleases*/genetics
RNA Cleavage ; Endoribonucleases ; RNA/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
FXR Maintains the Intestinal Barrier and Stemness by Regulating CYP11A1-Mediated Corticosterone Synthesis in Biliary Obstruction Diseases.
Autorzy:
Li Z; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.; NHC Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, China.; Key Laboratory of the Diagnosis and Treatment of Organ Transplantation, Research Unit of Collaborative Diagnosis and Treatment for Hepatobiliary and Pancreatic Cancer, Chinese Academy of Medical Sciences (2019RU019), Hangzhou 310003, China.; Key Laboratory of Organ Transplantation, Research Center for Diagnosis and Treatment of Hepatobiliary Diseases, Hangzhou 310003, China.
Dong H; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.; NHC Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, China.; Key Laboratory of the Diagnosis and Treatment of Organ Transplantation, Research Unit of Collaborative Diagnosis and Treatment for Hepatobiliary and Pancreatic Cancer, Chinese Academy of Medical Sciences (2019RU019), Hangzhou 310003, China.; Key Laboratory of Organ Transplantation, Research Center for Diagnosis and Treatment of Hepatobiliary Diseases, Hangzhou 310003, China.
Bian S; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.; NHC Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, China.; Key Laboratory of the Diagnosis and Treatment of Organ Transplantation, Research Unit of Collaborative Diagnosis and Treatment for Hepatobiliary and Pancreatic Cancer, Chinese Academy of Medical Sciences (2019RU019), Hangzhou 310003, China.; Key Laboratory of Organ Transplantation, Research Center for Diagnosis and Treatment of Hepatobiliary Diseases, Hangzhou 310003, China.
Wu H; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.; NHC Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, China.; Key Laboratory of the Diagnosis and Treatment of Organ Transplantation, Research Unit of Collaborative Diagnosis and Treatment for Hepatobiliary and Pancreatic Cancer, Chinese Academy of Medical Sciences (2019RU019), Hangzhou 310003, China.; Key Laboratory of Organ Transplantation, Research Center for Diagnosis and Treatment of Hepatobiliary Diseases, Hangzhou 310003, China.
Song W; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.; NHC Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, China.; Key Laboratory of the Diagnosis and Treatment of Organ Transplantation, Research Unit of Collaborative Diagnosis and Treatment for Hepatobiliary and Pancreatic Cancer, Chinese Academy of Medical Sciences (2019RU019), Hangzhou 310003, China.; Key Laboratory of Organ Transplantation, Research Center for Diagnosis and Treatment of Hepatobiliary Diseases, Hangzhou 310003, China.
Jia X; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.; NHC Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, China.; Key Laboratory of the Diagnosis and Treatment of Organ Transplantation, Research Unit of Collaborative Diagnosis and Treatment for Hepatobiliary and Pancreatic Cancer, Chinese Academy of Medical Sciences (2019RU019), Hangzhou 310003, China.; Key Laboratory of Organ Transplantation, Research Center for Diagnosis and Treatment of Hepatobiliary Diseases, Hangzhou 310003, China.
Chen J; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.; NHC Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, China.; Key Laboratory of the Diagnosis and Treatment of Organ Transplantation, Research Unit of Collaborative Diagnosis and Treatment for Hepatobiliary and Pancreatic Cancer, Chinese Academy of Medical Sciences (2019RU019), Hangzhou 310003, China.; Key Laboratory of Organ Transplantation, Research Center for Diagnosis and Treatment of Hepatobiliary Diseases, Hangzhou 310003, China.
Zhu X; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.; NHC Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, China.; Key Laboratory of the Diagnosis and Treatment of Organ Transplantation, Research Unit of Collaborative Diagnosis and Treatment for Hepatobiliary and Pancreatic Cancer, Chinese Academy of Medical Sciences (2019RU019), Hangzhou 310003, China.; Key Laboratory of Organ Transplantation, Research Center for Diagnosis and Treatment of Hepatobiliary Diseases, Hangzhou 310003, China.
Zhao L; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.; NHC Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, China.; Key Laboratory of the Diagnosis and Treatment of Organ Transplantation, Research Unit of Collaborative Diagnosis and Treatment for Hepatobiliary and Pancreatic Cancer, Chinese Academy of Medical Sciences (2019RU019), Hangzhou 310003, China.; Key Laboratory of Organ Transplantation, Research Center for Diagnosis and Treatment of Hepatobiliary Diseases, Hangzhou 310003, China.
Xuan Z; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.; NHC Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, China.; Key Laboratory of the Diagnosis and Treatment of Organ Transplantation, Research Unit of Collaborative Diagnosis and Treatment for Hepatobiliary and Pancreatic Cancer, Chinese Academy of Medical Sciences (2019RU019), Hangzhou 310003, China.; Key Laboratory of Organ Transplantation, Research Center for Diagnosis and Treatment of Hepatobiliary Diseases, Hangzhou 310003, China.
Jin C; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.; NHC Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, China.; Key Laboratory of the Diagnosis and Treatment of Organ Transplantation, Research Unit of Collaborative Diagnosis and Treatment for Hepatobiliary and Pancreatic Cancer, Chinese Academy of Medical Sciences (2019RU019), Hangzhou 310003, China.; Key Laboratory of Organ Transplantation, Research Center for Diagnosis and Treatment of Hepatobiliary Diseases, Hangzhou 310003, China.
Zhou M; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.; NHC Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, China.; Key Laboratory of the Diagnosis and Treatment of Organ Transplantation, Research Unit of Collaborative Diagnosis and Treatment for Hepatobiliary and Pancreatic Cancer, Chinese Academy of Medical Sciences (2019RU019), Hangzhou 310003, China.; Key Laboratory of Organ Transplantation, Research Center for Diagnosis and Treatment of Hepatobiliary Diseases, Hangzhou 310003, China.
Zheng S; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.; NHC Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, China.; Key Laboratory of the Diagnosis and Treatment of Organ Transplantation, Research Unit of Collaborative Diagnosis and Treatment for Hepatobiliary and Pancreatic Cancer, Chinese Academy of Medical Sciences (2019RU019), Hangzhou 310003, China.; Key Laboratory of Organ Transplantation, Research Center for Diagnosis and Treatment of Hepatobiliary Diseases, Hangzhou 310003, China.
Song P; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.; NHC Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, China.; Key Laboratory of the Diagnosis and Treatment of Organ Transplantation, Research Unit of Collaborative Diagnosis and Treatment for Hepatobiliary and Pancreatic Cancer, Chinese Academy of Medical Sciences (2019RU019), Hangzhou 310003, China.; Key Laboratory of Organ Transplantation, Research Center for Diagnosis and Treatment of Hepatobiliary Diseases, Hangzhou 310003, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 30; Vol. 24 (17). Date of Electronic Publication: 2023 Aug 30.
Typ publikacji:
Journal Article
MeSH Terms:
Cholestasis*
Corticosterone*
Animals ; Mice ; Bile Acids and Salts ; Cholesterol Side-Chain Cleavage Enzyme ; Intestines
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
LH/hCG Regulation of Circular RNA in Mural Granulosa Cells during the Periovulatory Period in Mice.
Autorzy:
Chakravarthi VP; Department of Cell Biology and Physiology, University of Kansas Medical Center, 3075 HLSIC, 3901 Rainbow Blvd., Kansas City, KS 66160, USA.
Hung WT; Department of Cell Biology and Physiology, University of Kansas Medical Center, 3075 HLSIC, 3901 Rainbow Blvd., Kansas City, KS 66160, USA.
Yellapu NK; Department of Biostatistics and Data Science, University of Kansas Medical Center, Kansas City, MO 66160, USA.
Gunewardena S; Department of Cell Biology and Physiology, University of Kansas Medical Center, 3075 HLSIC, 3901 Rainbow Blvd., Kansas City, KS 66160, USA.
Christenson LK; Department of Cell Biology and Physiology, University of Kansas Medical Center, 3075 HLSIC, 3901 Rainbow Blvd., Kansas City, KS 66160, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 23; Vol. 24 (17). Date of Electronic Publication: 2023 Aug 23.
Typ publikacji:
Journal Article
MeSH Terms:
RNA, Circular*/genetics
Granulosa Cells*
Female ; Animals ; Mice ; Ovarian Follicle ; Cholesterol Side-Chain Cleavage Enzyme ; Cytochrome P-450 CYP1A1
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 1509

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