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Wyszukujesz frazę ""comet assay"" wg kryterium: Temat


Tytuł :
Application of HepG2/C3A liver spheroids as a model system for genotoxicity studies.
Autorzy :
Coltman NJ; School of Biosciences, University of Birmingham, Birmingham, B15 2TT, United Kingdom. Electronic address: .
Coke BA; School of Biosciences, University of Birmingham, Birmingham, B15 2TT, United Kingdom.
Chatzi K; School of Biosciences, University of Birmingham, Birmingham, B15 2TT, United Kingdom.
Shepherd EL; Centre for Liver and Gastrointestinal Research, Institute of Immunology and Inflammation, and National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, The Medical School, University of Birmingham, Birmingham, B15 2TT, United Kingdom.
Lalor PF; Centre for Liver and Gastrointestinal Research, Institute of Immunology and Inflammation, and National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, The Medical School, University of Birmingham, Birmingham, B15 2TT, United Kingdom.
Schulz-Utermoehl T; Sygnature Discovery, The Discovery Building, BioCity, Pennyfoot Street, Nottingham, United Kingdom.
Hodges NJ; School of Biosciences, University of Birmingham, Birmingham, B15 2TT, United Kingdom. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2021 Jul 01; Vol. 345, pp. 34-45. Date of Electronic Publication: 2021 Apr 15.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Animal Testing Alternatives*
Comet Assay*
4-Nitroquinoline-1-oxide/*toxicity
Anthracenes/*toxicity
Benzo(a)pyrene/*toxicity
Hepatocytes/*drug effects
Imidazoles/*toxicity
Liver/*drug effects
4-Nitroquinoline-1-oxide/metabolism ; Activation, Metabolic ; Anthracenes/metabolism ; Benzo(a)pyrene/metabolism ; DNA Damage ; Gene Expression Regulation, Enzymologic ; Hep G2 Cells ; Hepatocytes/enzymology ; Hepatocytes/pathology ; Histones/metabolism ; Humans ; Imidazoles/metabolism ; Liver/enzymology ; Liver/pathology ; Phosphorylation ; Spheroids, Cellular ; Time Factors
Czasopismo naukowe
Tytuł :
B-Comet Assay (Comet Assay on Buccal Cells) for the Evaluation of Primary DNA Damage in Human Biomonitoring Studies.
Autorzy :
Russo C; Department of Pharmaceutical Sciences (Unit of Public Health), University of Perugia, Via del Giochetto, 06122 Perugia, Italy.
Acito M; Department of Pharmaceutical Sciences (Unit of Public Health), University of Perugia, Via del Giochetto, 06122 Perugia, Italy.
Fatigoni C; Department of Pharmaceutical Sciences (Unit of Public Health), University of Perugia, Via del Giochetto, 06122 Perugia, Italy.
Villarini M; Department of Pharmaceutical Sciences (Unit of Public Health), University of Perugia, Via del Giochetto, 06122 Perugia, Italy.
Moretti M; Department of Pharmaceutical Sciences (Unit of Public Health), University of Perugia, Via del Giochetto, 06122 Perugia, Italy.
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Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2020 Dec 10; Vol. 17 (24). Date of Electronic Publication: 2020 Dec 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Monitoring*/methods
Comet Assay*
DNA Damage*
Lymphocytes*/pathology
Female ; Humans ; Leukocytes/pathology ; Male ; Mouth Mucosa/cytology
Czasopismo naukowe
Tytuł :
Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results.
Autorzy :
Møller P; Department of Public Health, Section of Environmental Health, University of Copenhagen, Copenhagen, Denmark. .
Azqueta A; Department of Pharmacology and Toxicology, University of Navarra, Pamplona, Spain.; IdiSNA, Navarra Institute for Health Research, Pamplona, Spain.
Boutet-Robinet E; Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, Toulouse, France.
Koppen G; VITO-HEALTH, Mol, Belgium.
Bonassi S; Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele Pisana, Rome, Italy.; Department of Human Sciences and Quality of Life Promotion, San Raffaele University, Rome, Italy.
Milić M; Mutagenesis Unit, Institute for Medical Research and Occupational Health, Zagreb, Croatia.
Gajski G; Mutagenesis Unit, Institute for Medical Research and Occupational Health, Zagreb, Croatia.
Costa S; Environmental Health Department, National Institute of Health Dr Ricardo Jorge, Porto, Portugal.; Epidemiological Research Unit (EPIUnit), Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal.
Teixeira JP; Environmental Health Department, National Institute of Health Dr Ricardo Jorge, Porto, Portugal.; Epidemiological Research Unit (EPIUnit), Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal.
Costa Pereira C; Environmental Health Department, National Institute of Health Dr Ricardo Jorge, Porto, Portugal.; Epidemiological Research Unit (EPIUnit), Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal.
Dusinska M; Health Effects Laboratory, Department of Environmental Chemistry, Norwegian Institute for Air Research (NILU), Kjeller, Norway.
Godschalk R; Department of Pharmacology & Toxicology, School for Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, the Netherlands.
Brunborg G; Section of Molecular Toxicology, Department of Environmental Health, Norwegian Institute of Public Health Skøyen, Oslo, Norway.
Gutzkow KB; Section of Molecular Toxicology, Department of Environmental Health, Norwegian Institute of Public Health Skøyen, Oslo, Norway.
Giovannelli L; Department of Neuroscience, Psychology, Pharmacology and Child Health (NEUROFARBA), Section Pharmacology and Toxicology, University of Florence, Florence, Italy.
Cooke MS; Oxidative Stress Group, Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, FL, USA.
Richling E; Food Chemistry & Toxicology, Department of Chemistry, University of Kaiserslautern, Kaiserslautern, Germany.
Laffon B; Universidade da Coruña, Grupo DICOMOSA, Centro de Investigaciones Científicas Avanzadas (CICA), Departamento de Psicología, Facultad de Ciencias de la Educación, Coruña, Spain.; Instituto de Investigación Biomédica de A Coruña (INIBIC), AE CICA-INIBIC, Coruña, Spain.
Valdiglesias V; Universidade da Coruña, Grupo DICOMOSA, Centro de Investigaciones Científicas Avanzadas (CICA), Departamento de Psicología, Facultad de Ciencias de la Educación, Coruña, Spain.; Instituto de Investigación Biomédica de A Coruña (INIBIC), AE CICA-INIBIC, Coruña, Spain.
Basaran N; Department of Toxicology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.
Del Bo' C; Division of Human Nutrition, Department of Food, Environmental and Nutritional Sciences (DeFENS), Università degli Studi di Milano, Milan, Italy.
Zegura B; Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia.
Novak M; Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia.
Stopper H; Institute of Pharmacology and Toxicology, University of Würzburg, Würzburg, Germany.
Vodicka P; Institute of Experimental Medicine, Czech Academy of Sciences, Prague, Czech Republic.; Biomedical Center, Medical Faculty in Pilsen, Charles University in Prague, Prague, Czech Republic.
Vodenkova S; Institute of Experimental Medicine, Czech Academy of Sciences, Prague, Czech Republic.; Biomedical Center, Medical Faculty in Pilsen, Charles University in Prague, Prague, Czech Republic.
de Andrade VM; Laboratory of Translational Biomedicine, University of Southern Santa Catarina, UNESC, Criciúma, Brazil.
Sramkova M; Department of Nanobiology, Cancer Research Institute, Biomedical Research Center of the Slovak Academy of Sciences, Bratislava, Slovakia.
Gabelova A; Department of Nanobiology, Cancer Research Institute, Biomedical Research Center of the Slovak Academy of Sciences, Bratislava, Slovakia.
Collins A; Department of Nutrition, University of Oslo, Oslo, Norway.
Langie SAS; Department of Pharmacology & Toxicology, School for Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, the Netherlands.; Centre for Environmental Sciences, Hasselt University, Hasselt, Belgium.
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Źródło :
Nature protocols [Nat Protoc] 2020 Dec; Vol. 15 (12), pp. 3817-3826. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Research Design*
Comet Assay/*methods
Comet Assay/standards ; Consensus ; Guideline Adherence/statistics & numerical data ; Humans ; Laboratories
Czasopismo naukowe
Tytuł :
Revisiting the evidence for genotoxicity of acrylamide (AA), key to risk assessment of dietary AA exposure.
Autorzy :
Eisenbrand G; University of Kaiserslautern, Germany (Retired), Kühler Grund 48/1, 69126, Heidelberg, Germany. .
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Źródło :
Archives of toxicology [Arch Toxicol] 2020 Sep; Vol. 94 (9), pp. 2939-2950. Date of Electronic Publication: 2020 Jun 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Comet Assay*
Dietary Exposure*
Acrylamide/*toxicity
Carcinogens/*toxicity
Animals ; Hepatocytes ; Humans ; Male ; Rats
Czasopismo naukowe
Tytuł :
Mutagenic and genotoxic activities of Phospholipase A 2 Bothropstoxin-I from Bothrops jararacussu in Drosophila melanogaster and human cell lines.
Autorzy :
Naves MPC; Institute of Biotechnology, Federal University of Uberlândia, Campus Umuarama, Uberlândia, MG, Brazil.
de Morais CR; Institute of Biotechnology, Federal University of Uberlândia, Campus Umuarama, Uberlândia, MG, Brazil.
de Freitas V; Institute of Biotechnology, Federal University of Uberlândia, Campus Umuarama, Uberlândia, MG, Brazil.
Ribeiro DL; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.
Lopes DS; Multidisciplinary Institute in Health, Federal University of Bahia, Vitória da Conquista, BA, Brazil.
Antunes LMG; Department of Clinical Analyses, Toxicology and Food Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
de Melo Rodrigues V; Institute of Biotechnology, Federal University of Uberlândia, Campus Umuarama, Uberlândia, MG, Brazil.
de Rezende AAA; Institute of Exact and Natural Sciences of Pontal, Federal University of Uberlândia, Campus Pontal, Ituiutaba, MG, Brazil.
Spanó MA; Institute of Biotechnology, Federal University of Uberlândia, Campus Umuarama, Uberlândia, MG, Brazil. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jul 01; Vol. 182, pp. 1602-1610. Date of Electronic Publication: 2021 May 24.
Typ publikacji :
Journal Article
MeSH Terms :
Bothrops/*metabolism
Crotalid Venoms/*toxicity
Phospholipases A2/*metabolism
Animals ; Cell Line ; Cell Survival/drug effects ; Comet Assay ; Drosophila melanogaster ; Human Umbilical Vein Endothelial Cells ; Humans ; Mutation/genetics
Czasopismo naukowe
Tytuł :
Assessment of Cytogenetic Damage and Cholinesterases' Activity in Workers Occupationally Exposed to Pesticides in Zamora-Jacona, Michoacan, Mexico.
Autorzy :
Valencia-Quintana R; Laboratorio 'Rafael Villalobos-Pietrini' de Toxicología Genómica y Química Ambiental, Facultad de Agrobiología, Universidad Autónoma de Tlaxcala, CA Genética y Ambiente UATLX-CA 223, Red Temática de Toxicología de Plaguicidas, Tlaxcala 90120, Mexico.
López-Durán RM; Laboratorio de Biomembranas, División de Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana-Iztapalapa, Ciudad de México 09340, Mexico.
Milić M; Mutagenesis Unit, Institute for Medical Research and Occupational Health, Ksaverska Cesta 2, 10000 Zagreb, Croatia.
Bonassi S; Department of Human Sciences and Quality of Life Promotion, San Rafaele University, 00166 Rome, Italy.; Unit of Clinical and Molecular Epidemiology, IRCCS San Rafaele Pisana, 00166 Rome, Italy.
Ochoa-Ocaña MA; Unidad Académica de Estudios Regionales, Coordinación de Humanidades, UNAM, Jiquilpan 59510, Mexico.
Uriostegui-Acosta MO; Escuela Superior de Ciencias Naturales, Universidad Autónoma de Guerrero Chilpancingo 39105, Mexico.
Pérez-Flores GA; Laboratorio 'Rafael Villalobos-Pietrini' de Toxicología Genómica y Química Ambiental, Facultad de Agrobiología, Universidad Autónoma de Tlaxcala, CA Genética y Ambiente UATLX-CA 223, Red Temática de Toxicología de Plaguicidas, Tlaxcala 90120, Mexico.
Gómez-Olivares JL; Laboratorio de Biomembranas, División de Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana-Iztapalapa, Ciudad de México 09340, Mexico.
Sánchez-Alarcón J; Laboratorio 'Rafael Villalobos-Pietrini' de Toxicología Genómica y Química Ambiental, Facultad de Agrobiología, Universidad Autónoma de Tlaxcala, CA Genética y Ambiente UATLX-CA 223, Red Temática de Toxicología de Plaguicidas, Tlaxcala 90120, Mexico.
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Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2021 Jun 10; Vol. 18 (12). Date of Electronic Publication: 2021 Jun 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Occupational Exposure*/adverse effects
Occupational Exposure*/analysis
Pesticides*/toxicity
Cholinesterases ; Comet Assay ; Cytogenetic Analysis ; DNA Damage ; Humans ; Lymphocytes ; Mexico ; Micronucleus Tests ; Mouth Mucosa
Czasopismo naukowe
Tytuł :
Evaluation of DNA damage and toxicological methodology development: A bibliometric study.
Autorzy :
Nascimento FA; Laboratório de Mutagênese (LabMut), Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Brazil.
Silva DME; Laboratório de Mutagênese (LabMut), Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Brazil.
Nunes HF; Laboratório de Mutagênese (LabMut), Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Brazil.
Parise MR; Laboratório de Mutagênese (LabMut), Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Brazil.
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Źródło :
Human & experimental toxicology [Hum Exp Toxicol] 2020 Jun; Vol. 39 (6), pp. 870-880. Date of Electronic Publication: 2020 Feb 07.
Typ publikacji :
Journal Article
MeSH Terms :
Comet Assay*
DNA Damage*
Bibliometrics ; Databases, Factual ; Toxicology/methods
Czasopismo naukowe
Tytuł :
Cytogenotoxicity evaluation of a heavy metal mixture, detected in a polluted urban wetland: Micronucleus and comet induction in the Indian green frog (Euphlyctis hexadactylus) erythrocytes and the Allium cepa bioassay.
Autorzy :
Jayawardena UA; Department of Zoology and Environment Sciences, Faculty of Science, University of Colombo, Colombo 3, Sri Lanka.
Wickramasinghe DD; Department of Zoology and Environment Sciences, Faculty of Science, University of Colombo, Colombo 3, Sri Lanka.
Udagama PV; Department of Zoology and Environment Sciences, Faculty of Science, University of Colombo, Colombo 3, Sri Lanka. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2021 Aug; Vol. 277, pp. 130278. Date of Electronic Publication: 2021 Mar 13.
Typ publikacji :
Journal Article
MeSH Terms :
Metals, Heavy*/analysis
Metals, Heavy*/toxicity
Rana clamitans*
Water Pollutants, Chemical*/analysis
Water Pollutants, Chemical*/toxicity
Animals ; Biological Assay ; Comet Assay ; Ecosystem ; Environmental Monitoring ; Erythrocytes/chemistry ; Onions ; Risk Assessment ; Sri Lanka ; Wetlands
Czasopismo naukowe
Tytuł :
Genotoxicity Study of Vitex megapotamica (Spreng.) Moldenke.
Autorzy :
Ribeiro RCL; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Botelho ELL; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Donadel G; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Ames ML; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Nunes B; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Tramontini S; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Soares AA; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Alberton O; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Jacomassi E; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Gasparotto Junior A; Laboratory of Cardiovascular Pharmacology (LaFaC), Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, MS, Brazil.
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Źródło :
Journal of medicinal food [J Med Food] 2021 Jul; Vol. 24 (7), pp. 762-765. Date of Electronic Publication: 2021 Feb 02.
Typ publikacji :
Journal Article
MeSH Terms :
Vitex*
Animals ; Brazil ; Comet Assay ; DNA Damage ; Micronucleus Tests ; Plant Extracts/toxicity ; Plant Leaves ; Rats
Czasopismo naukowe
Tytuł :
Changes in genotoxicity, inflammatory and oxidative stress parameters of workers in marble processing plants.
Autorzy :
Beci T M; Department of Pharmacology, Faculty of Pharmacy, Ataturk University, Erzurum, 25240, Turkey.
Çi Lekar Ş; Department of Chest Diseases, Faculty of Medicine, Afyonkarahisar University of Health Sciences, Afyonkarahisar, 03030, Turkey.
Başaran MM; Department of Otorhinolaryngology, Faculty of Medicine, Kafkas University, Kars, 36100, Turkey.
Koca HB; Department of Medical Biochemistry, Faculty of Medicine, Afyonkarahisar University of Health Sciences, Afyonkarahisar, 03030, Turkey.
Çeli K S; Department of Medical Biochemistry, Faculty of Medicine, Afyonkarahisar University of Health Sciences, Afyonkarahisar, 03030, Turkey.
Aydin Di Lsi Z S; Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Hacettepe University, Ankara, 06100, Turkey. Electronic address: .
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Źródło :
Environmental research [Environ Res] 2021 Jun; Vol. 197, pp. 111209. Date of Electronic Publication: 2021 Apr 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Occupational Exposure*/adverse effects
Calcium Carbonate ; Comet Assay ; DNA Damage ; Humans ; Micronucleus Tests ; Mouth Mucosa ; Oxidative Stress ; Turkey
Czasopismo naukowe
Tytuł :
Applications of CometChip for Environmental Health Studies.
Autorzy :
Chao C; Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
Engelward BP; Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
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Źródło :
Chemical research in toxicology [Chem Res Toxicol] 2020 Jul 20; Vol. 33 (7), pp. 1528-1538. Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Comet Assay*
Environmental Health*
DNA/*analysis
Animals ; DNA Damage ; Humans
Czasopismo naukowe
Tytuł :
Performance of high-throughput CometChip assay using primary human hepatocytes: a comparison of DNA damage responses with in vitro human hepatoma cell lines.
Autorzy :
Seo JE; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, Jefferson, AR, 72079, USA.
Wu Q; Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR, 72079, USA.
Bryant M; Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR, 72079, USA.
Ren L; Division of Systems Biology, National Center for Toxicological Research, Jefferson, AR, 72079, USA.
Shi Q; Division of Systems Biology, National Center for Toxicological Research, Jefferson, AR, 72079, USA.
Robison TW; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, 20993, USA.
Mei N; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, Jefferson, AR, 72079, USA.
Manjanatha MG; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, Jefferson, AR, 72079, USA.
Guo X; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, Jefferson, AR, 72079, USA. .
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Źródło :
Archives of toxicology [Arch Toxicol] 2020 Jun; Vol. 94 (6), pp. 2207-2224. Date of Electronic Publication: 2020 Apr 22.
Typ publikacji :
Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Comet Assay*
DNA Damage*
High-Throughput Screening Assays*
Hepatocytes/*drug effects
Mutagens/*toxicity
Activation, Metabolic ; Dose-Response Relationship, Drug ; Female ; Hep G2 Cells ; Hepatocytes/pathology ; Humans ; Male ; Mutagens/metabolism ; Race Factors ; Reproducibility of Results ; Risk Assessment ; Sex Factors
Czasopismo naukowe
Tytuł :
Residential exposure to radon and levels of histone γH2AX and DNA damage in peripheral blood lymphocytes of residents of Kowary city regions (Poland).
Autorzy :
K W; Radiological Protection Dept, Nofer Institute of Occupational Medicine, ul. Św. Teresy od Dzieciątka Jezus 8, 91-348, Łódź, Poland. Electronic address: .
J O; Radiological Protection Dept, Nofer Institute of Occupational Medicine, ul. Św. Teresy od Dzieciątka Jezus 8, 91-348, Łódź, Poland.
P P; Radiological Protection Dept, Nofer Institute of Occupational Medicine, ul. Św. Teresy od Dzieciątka Jezus 8, 91-348, Łódź, Poland.
K DG; Toxicology and Carcinogenesis Dept, Nofer Institute of Occupational Medicine, ul. Św. Teresy od Dzieciątka Jezus 8, 91-348, Łódź, Poland.
K K; Toxicology and Carcinogenesis Dept, Nofer Institute of Occupational Medicine, ul. Św. Teresy od Dzieciątka Jezus 8, 91-348, Łódź, Poland.
M Z; Radiological Protection Dept, Nofer Institute of Occupational Medicine, ul. Św. Teresy od Dzieciątka Jezus 8, 91-348, Łódź, Poland.
M B; Radiological Protection Dept, Nofer Institute of Occupational Medicine, ul. Św. Teresy od Dzieciątka Jezus 8, 91-348, Łódź, Poland.
M S; Toxicology and Carcinogenesis Dept, Nofer Institute of Occupational Medicine, ul. Św. Teresy od Dzieciątka Jezus 8, 91-348, Łódź, Poland.
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Źródło :
Chemosphere [Chemosphere] 2020 May; Vol. 247, pp. 125748. Date of Electronic Publication: 2019 Dec 24.
Typ publikacji :
Journal Article
MeSH Terms :
Environmental Exposure*
Air Pollutants, Radioactive/*toxicity
Comet Assay/*standards
Lymphocytes/*radiation effects
Radon/*analysis
Comet Assay/methods ; DNA Damage/radiation effects ; Histones/analysis ; Histones/genetics ; Humans ; Poland ; Radon/pharmacology
Czasopismo naukowe
Tytuł :
Investigating the radioprotective effect of sesamol oral consumption against gamma irradiation in mice by micronucleus and alkaline comet assays.
Autorzy :
Majdaeen M; Department of Radiotherapy and Oncology, Razi Hospital, Rasht, Iran.
Banaei A; Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran; Department of Radiology, Faculty of Paramedical Sciences, AJA University of Medical Sciences, Tehran, Iran.
Abedi-Firouzjah R; Department of Medical Physics Radiobiology and Radiation Protection, Babol University of Medical Sciences, Babol, Iran. Electronic address: .
Ebrahimnejad Gorji K; Department of Medical Physics Radiobiology and Radiation Protection, Babol University of Medical Sciences, Babol, Iran.
Ataei G; Department of Radiology Technology, Faculty of Paramedical Sciences, Babol University of Medical Science, Babol, Iran.
Momeni F; Medical Physics and Medical Engineering Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: .
Zamani H; Department of Medical Physics, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
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Źródło :
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine [Appl Radiat Isot] 2020 May; Vol. 159, pp. 109091. Date of Electronic Publication: 2020 Feb 22.
Typ publikacji :
Journal Article
MeSH Terms :
Comet Assay*
Gamma Rays*
Micronucleus Tests*
Benzodioxoles/*administration & dosage
Phenols/*administration & dosage
Radiation-Protective Agents/*administration & dosage
Administration, Oral ; Animals ; Blood Cells/drug effects ; Bone Marrow/drug effects ; Mice
Czasopismo naukowe
Tytuł :
Classification of DNA damages on segmented comet assay images using convolutional neural network.
Autorzy :
Atila Ü; Department of Computer Engineering, Faculty of Engineering, Karabuk University, Karabuk, Turkey.
Baydilli YY; Department of Computer Engineering, Faculty of Engineering, Karabuk University, Karabuk, Turkey.
Sehirli E; Department of Medical Engineering, Faculty of Engineering, Karabuk University, Karabuk, Turkey. Electronic address: .
Turan MK; Department of Medical Biology, Faculty of Medicine, Karabuk University, Karabuk, Turkey.
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Źródło :
Computer methods and programs in biomedicine [Comput Methods Programs Biomed] 2020 Apr; Vol. 186, pp. 105192. Date of Electronic Publication: 2019 Nov 06.
Typ publikacji :
Journal Article
MeSH Terms :
Comet Assay*
DNA Damage*
Neural Networks, Computer*
Algorithms ; Humans ; Image Processing, Computer-Assisted/methods ; Lymphocytes/ultrastructure ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Gasoline-station workers in Brazil: Benzene exposure; Genotoxic and immunotoxic effects.
Autorzy :
Poça KSD; Área Técnica Ambiente, Trabalho e Câncer, Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA, Rua Marquês do Pombal, 125/5º andar - Centro, Rio de Janeiro, RJ, CEP 20230-240, Brazil; Laboratório de Mutagênese Ambiental, Departamento de Bioquímica, Instituto Biomédico, Universidade Federal do Estado do Rio de Janeiro (UNIRIO) - Rua Frei Caneca, 94/4º andar - Centro, Rio de Janeiro. CEP 20211-010, Brazil. Electronic address: .
Giardini I; Área Técnica Ambiente, Trabalho e Câncer, Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA, Rua Marquês do Pombal, 125/5º andar - Centro, Rio de Janeiro, RJ, CEP 20230-240, Brazil; Laboratório de Mutagênese Ambiental, Departamento de Bioquímica, Instituto Biomédico, Universidade Federal do Estado do Rio de Janeiro (UNIRIO) - Rua Frei Caneca, 94/4º andar - Centro, Rio de Janeiro. CEP 20211-010, Brazil. Electronic address: .
Silva PVB; Área Técnica Ambiente, Trabalho e Câncer, Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA, Rua Marquês do Pombal, 125/5º andar - Centro, Rio de Janeiro, RJ, CEP 20230-240, Brazil; Laboratório de Mutagênese Ambiental, Departamento de Bioquímica, Instituto Biomédico, Universidade Federal do Estado do Rio de Janeiro (UNIRIO) - Rua Frei Caneca, 94/4º andar - Centro, Rio de Janeiro. CEP 20211-010, Brazil. Electronic address: .
Geraldino BR; Área Técnica Ambiente, Trabalho e Câncer, Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA, Rua Marquês do Pombal, 125/5º andar - Centro, Rio de Janeiro, RJ, CEP 20230-240, Brazil; Laboratório de Mutagênese Ambiental, Departamento de Bioquímica, Instituto Biomédico, Universidade Federal do Estado do Rio de Janeiro (UNIRIO) - Rua Frei Caneca, 94/4º andar - Centro, Rio de Janeiro. CEP 20211-010, Brazil. Electronic address: .b.
Bellomo A; Área Técnica Ambiente, Trabalho e Câncer, Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA, Rua Marquês do Pombal, 125/5º andar - Centro, Rio de Janeiro, RJ, CEP 20230-240, Brazil; Laboratório de Mutagênese Ambiental, Departamento de Bioquímica, Instituto Biomédico, Universidade Federal do Estado do Rio de Janeiro (UNIRIO) - Rua Frei Caneca, 94/4º andar - Centro, Rio de Janeiro. CEP 20211-010, Brazil. Electronic address: .
Alves JA; Área Técnica Ambiente, Trabalho e Câncer, Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA, Rua Marquês do Pombal, 125/5º andar - Centro, Rio de Janeiro, RJ, CEP 20230-240, Brazil; Laboratório de Mutagênese Ambiental, Departamento de Bioquímica, Instituto Biomédico, Universidade Federal do Estado do Rio de Janeiro (UNIRIO) - Rua Frei Caneca, 94/4º andar - Centro, Rio de Janeiro. CEP 20211-010, Brazil. Electronic address: .
Conde TR; Departamento de Farmacologia e Toxicologia, Instituto Nacional de Controle de Qualidade em Saúde, Fundação Oswaldo Cruz (INCQS/FIOCRUZ) - Avenida Brasil, 4365 - Manguinhos, Rio de Janeiro, RJ, DFT/INCQS/FIOCRUZ, CEP 21040-900, Brazil. Electronic address: .b.
Zamith HPDS; Departamento de Farmacologia e Toxicologia, Instituto Nacional de Controle de Qualidade em Saúde, Fundação Oswaldo Cruz (INCQS/FIOCRUZ) - Avenida Brasil, 4365 - Manguinhos, Rio de Janeiro, RJ, DFT/INCQS/FIOCRUZ, CEP 21040-900, Brazil. Electronic address: .
Otero UB; Área Técnica Ambiente, Trabalho e Câncer, Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA, Rua Marquês do Pombal, 125/5º andar - Centro, Rio de Janeiro, RJ, CEP 20230-240, Brazil. Electronic address: .
Ferraris FK; Departamento de Farmacologia e Toxicologia, Instituto Nacional de Controle de Qualidade em Saúde, Fundação Oswaldo Cruz (INCQS/FIOCRUZ) - Avenida Brasil, 4365 - Manguinhos, Rio de Janeiro, RJ, DFT/INCQS/FIOCRUZ, CEP 21040-900, Brazil. Electronic address: .
Friedrich K; Centro de Estudos em Saúde do Trabalhador e Ecologia Humana, Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz (CESTEH/ENSP/FIOCRUZ) - Rua Leopoldo Bulhões, 1480 - Manguinho, Rio de Janeiro, RJ, CEP 21041-210, Brazil. Electronic address: .
Sarpa M; Área Técnica Ambiente, Trabalho e Câncer, Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA, Rua Marquês do Pombal, 125/5º andar - Centro, Rio de Janeiro, RJ, CEP 20230-240, Brazil; Laboratório de Mutagênese Ambiental, Departamento de Bioquímica, Instituto Biomédico, Universidade Federal do Estado do Rio de Janeiro (UNIRIO) - Rua Frei Caneca, 94/4º andar - Centro, Rio de Janeiro. CEP 20211-010, Brazil. Electronic address: .
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Źródło :
Mutation research [Mutat Res] 2021 May; Vol. 865, pp. 503322. Date of Electronic Publication: 2021 Feb 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Occupational Exposure*/adverse effects
Occupational Exposure*/analysis
Occupational Exposure*/statistics & numerical data
Benzene/*toxicity
Gasoline/*toxicity
Immune System/*drug effects
Adult ; Aged ; Air Pollutants, Occupational/toxicity ; Brazil/epidemiology ; Comet Assay ; Cross-Sectional Studies ; DNA Damage/drug effects ; DNA Damage/immunology ; Female ; Humans ; Immune System/metabolism ; Immunomodulation/drug effects ; Inhalation Exposure/adverse effects ; Inhalation Exposure/analysis ; Lymphocyte Count ; Male ; Micronucleus Tests ; Middle Aged ; Mutagenicity Tests ; Stress, Physiological/drug effects ; Stress, Physiological/immunology ; T-Lymphocytes/drug effects ; T-Lymphocytes/pathology ; Young Adult
Czasopismo naukowe
Tytuł :
'Site of contact genotoxicity' assessment for implants - Potential use of single cell gel electrophoresis in biocompatibility testing of medical devices.
Autorzy :
Kumaravel TS; GLR Laboratories (Europe) Pvt Ltd, Sharnbrook, MK44 1LZ, United Kingdom; GLR Laboratories Pvt Ltd, Chennai, 600068, India. Electronic address: .
Brabu B; Department of Fiber Science & Apparel Design, College of Human Ecology, Cornell University, Ithaca, NY, 14853, USA.
Parthiban N; GLR Laboratories Pvt Ltd, Chennai, 600068, India.
Murugan SS; GLR Laboratories Pvt Ltd, Chennai, 600068, India.
Jha AN; School of Biological and Marine Sciences, University of Plymouth, Plymouth, PL4 8AA, United Kingdom.
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Źródło :
Toxicology letters [Toxicol Lett] 2021 May 01; Vol. 341, pp. 59-67. Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Journal Article
MeSH Terms :
Materials Testing*
Prostheses and Implants*
Acrylic Resins/*chemistry
Comet Assay/*methods
Ethyl Methanesulfonate/*toxicity
Animals ; Ethyl Methanesulfonate/administration & dosage ; Ethyl Methanesulfonate/chemistry ; Hepatocytes/drug effects ; Rats ; Rats, Wistar ; Water
Czasopismo naukowe
Tytuł :
In vivo treatment with a subacute low dose of 3-nitropropionic acid does not induce genotoxicity or mutagenicity in rats.
Autorzy :
Techera Antunes FT; Program of Postgraduation in Cellular and Molecular Biology Applied to Health, Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil. Electronic address: .
Caminski ES; Department of Pharmacoscience, Federal University Science of Health of Porto Alegre (UFCSPA), Rio Grande do Sul, Brazil. Electronic address: .
Picada JN; Laboratory of Genetic Toxicology, Lutheran University of Brazil, Canoas, RS, Brazil. Electronic address: .
Regner AP; Program of Postgraduation in Cellular and Molecular Biology Applied to Health, Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil. Electronic address: .
Dallegrave E; Department of Pharmacoscience, Federal University Science of Health of Porto Alegre (UFCSPA), Rio Grande do Sul, Brazil. Electronic address: .
Hubner de Souza A; Program of Postgraduation in Cellular and Molecular Biology Applied to Health, Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil. Electronic address: .
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Źródło :
Toxicon : official journal of the International Society on Toxinology [Toxicon] 2021 May; Vol. 195, pp. 20-23. Date of Electronic Publication: 2021 Mar 06.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Damage*
Mutagens*/toxicity
Nitro Compounds/*toxicity
Propionates/*toxicity
Animals ; Comet Assay ; Dose-Response Relationship, Drug ; Micronucleus Tests ; Mutagenicity Tests ; Rats
Czasopismo naukowe
Tytuł :
Evaluation of the genotoxic and cytotoxic effects of exposure to the herbicide 2,4-dichlorophenoxyacetic acid in Astyanax lacustris (Pisces, Characidae) and the potential for its removal from contaminated water using a biosorbent.
Autorzy :
Zafra-Lemos L; Department of Biotechnology, Genetics and Cellular Biology, Maringá State University, Av. Colombo, 5790 - Zona 7, Maringá, Paraná, Brazil. Electronic address: .
Cusioli LF; Department of Chemical Engineering, Maringá State University, Av. Colombo, 5790 - Zona 7, Maringá, Paraná, Brazil.
Bergamasco R; Department of Chemical Engineering, Maringá State University, Av. Colombo, 5790 - Zona 7, Maringá, Paraná, Brazil.
Borin-Carvalho LA; Department of Biotechnology, Genetics and Cellular Biology, Maringá State University, Av. Colombo, 5790 - Zona 7, Maringá, Paraná, Brazil.
Portela-Castro ALB; Department of Biotechnology, Genetics and Cellular Biology, Maringá State University, Av. Colombo, 5790 - Zona 7, Maringá, Paraná, Brazil.
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Źródło :
Mutation research [Mutat Res] 2021 May; Vol. 865, pp. 503335. Date of Electronic Publication: 2021 Feb 13.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Characidae*/genetics
2,4-Dichlorophenoxyacetic Acid/*isolation & purification
2,4-Dichlorophenoxyacetic Acid/*toxicity
Biocompatible Materials/*pharmacokinetics
Environmental Restoration and Remediation/*methods
Absorption, Physicochemical/drug effects ; Animals ; Biocompatible Materials/chemistry ; Chromosome Aberrations/chemically induced ; Chromosome Aberrations/veterinary ; Cocos/chemistry ; Comet Assay ; Cytogenetic Analysis/veterinary ; DNA Damage ; Environmental Monitoring/methods ; Filtration/instrumentation ; Filtration/methods ; Herbicides/isolation & purification ; Herbicides/toxicity ; Mutagenicity Tests ; Water Pollutants, Chemical/isolation & purification ; Water Pollutants, Chemical/toxicity ; Water Purification/methods
Czasopismo naukowe
Tytuł :
Prednisone is genotoxic in mice and Drosophila melanogaster.
Autorzy :
de Oliveira LC; Laboratory of Radiobiology and Mutagenesis, Department of Genetics, Institute of Biological Sciences, Campus Samambaia, Universidade Federal de Goiás, 74690-900, Goiânia, GO, Brazil.
de Melo Bisneto AV; Laboratory of Radiobiology and Mutagenesis, Department of Genetics, Institute of Biological Sciences, Campus Samambaia, Universidade Federal de Goiás, 74690-900, Goiânia, GO, Brazil.
Puga SC; Laboratory of Radiobiology and Mutagenesis, Department of Genetics, Institute of Biological Sciences, Campus Samambaia, Universidade Federal de Goiás, 74690-900, Goiânia, GO, Brazil.
Fernandes AS; Laboratory of Radiobiology and Mutagenesis, Department of Genetics, Institute of Biological Sciences, Campus Samambaia, Universidade Federal de Goiás, 74690-900, Goiânia, GO, Brazil.
Véras JH; Laboratory of Radiobiology and Mutagenesis, Department of Genetics, Institute of Biological Sciences, Campus Samambaia, Universidade Federal de Goiás, 74690-900, Goiânia, GO, Brazil.
Cardoso CG; Laboratory of Radiobiology and Mutagenesis, Department of Histology, Embryology and Cell Biology, Institute of Biological Sciences, Campus Samambaia, Universidade Federal de Goiás, 74690-900, Goiânia, GO, Brazil.
Ribeiro E Silva C; Laboratory of Radiobiology and Mutagenesis, Department of Morphology, Institute of Biological Sciences, Campus Samambaia, Universidade Federal de Goiás, 74690-900, Goiânia, GO, Brazil.
Carneiro CC; Department of Biomedicine, School of Medical, Biomedical and Pharmaceutical Sciences, Pontifícia Universidade Católica de Goiás, 74605-010, Goiânia, GO, Brazil.
Chen-Chen L; Laboratory of Radiobiology and Mutagenesis, Department of Genetics, Institute of Biological Sciences, Campus Samambaia, Universidade Federal de Goiás, 74690-900, Goiânia, GO, Brazil. Electronic address: .
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Źródło :
Mutation research [Mutat Res] 2021 May; Vol. 865, pp. 503334. Date of Electronic Publication: 2021 Feb 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Damage/*drug effects
Prednisone/*adverse effects
Animals ; Animals, Genetically Modified ; Animals, Outbred Strains ; Comet Assay ; Drosophila melanogaster ; Female ; Male ; Mice ; Micronucleus Tests ; Mutagenicity Tests/methods ; Mutagens/toxicity
Czasopismo naukowe

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