Temat: "comet assay" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Oxidative damage and DNA repair in desiccated recalcitrant embryonic axes of Acer pseudoplatanus L.
Autorzy:: Plitta-Michalak BP; Department of Plant Physiology, Genetics and Biotechnology, University of Warmia and Mazury in Olsztyn, Oczapowskiego 1A/103, 10-719, Olsztyn, Poland. .
Ramos AA; Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto (U. Porto), Rua de Jorge Viterbo Ferreira 228, 4050-313, Porto, Portugal.; Interdisciplinary Center for Marine and Environmental Research (CIIMAR), University of Porto (U. Porto), Avenida General Norton de Matos, 4450-208, Matosinhos, Portugal.
Pupel P; Department of Plant Physiology, Genetics and Biotechnology, University of Warmia and Mazury in Olsztyn, Oczapowskiego 1A/103, 10-719, Olsztyn, Poland.
Michalak M; Department of Plant Physiology, Genetics and Biotechnology, University of Warmia and Mazury in Olsztyn, Oczapowskiego 1A/103, 10-719, Olsztyn, Poland.; Pokaż więcej
Źródło:: BMC plant biology [BMC Plant Biol] 2022 Jan 19; Vol. 22 (1), pp. 40. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji:: Journal Article
MeSH Terms:: DNA Repair*
Oxidative Stress*
Acer/*genetics
Comet Assay/*methods
Seeds/*genetics
Acer/chemistry ; Acer/growth & development ; Buffers ; DNA Fragmentation ; DNA-Formamidopyrimidine Glycosylase/metabolism ; Desiccation ; Guanosine/analogs & derivatives ; Guanosine/genetics ; Guanosine/metabolism ; Principal Component Analysis ; Reactive Oxygen Species/metabolism ; Reproducibility of Results ; Seeds/chemistry ; Seeds/growth & development ; Seeds/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 2.

Tytuł:: Ancient Sturgeons Possess Effective DNA Repair Mechanisms: Influence of Model Genotoxicants on Embryo Development of Sterlet, Acipenser ruthenus .
Autorzy:: Gazo I; South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Zátiší 728/II, 389 25 Vodňany, Czech Republic.
Franěk R; South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Zátiší 728/II, 389 25 Vodňany, Czech Republic.
Šindelka R; Laboratory of Gene Expression, Institute of Biotechnology-Biocev, Academy of Science of the Czech Republic, 252 50 Vestec, Czech Republic.
Lebeda I; South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Zátiší 728/II, 389 25 Vodňany, Czech Republic.
Shivaramu S; South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Zátiší 728/II, 389 25 Vodňany, Czech Republic.
Pšenička M; South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Zátiší 728/II, 389 25 Vodňany, Czech Republic.
Steinbach C; South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Zátiší 728/II, 389 25 Vodňany, Czech Republic.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Dec 22; Vol. 22 (1). Date of Electronic Publication: 2020 Dec 22.
Typ publikacji:: Journal Article
MeSH Terms:: DNA Damage*
DNA Repair*
Embryo, Nonmammalian/*drug effects
Embryonic Development/*drug effects
Fishes/*genetics
Animals ; Benzo(a)pyrene/toxicity ; Camptothecin/toxicity ; Comet Assay ; DNA Fragmentation/drug effects ; Embryo, Nonmammalian/embryology ; Embryo, Nonmammalian/metabolism ; Embryonic Development/genetics ; Etoposide/toxicity ; Female ; Fishes/embryology ; Male ; Mutagenicity Tests/methods ; Mutagens/toxicity

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 3.

Tytuł:: Human primary endothelial cells are impaired in nucleotide excision repair and sensitive to benzo[a]pyrene compared with smooth muscle cells and pericytes.
Autorzy:: Kress JM; Institute of Toxicology, University Medical Center, Mainz, 55131, Germany.
Dio LD; Institute of Toxicology, University Medical Center, Mainz, 55131, Germany.
Heck L; Institute of Toxicology, University Medical Center, Mainz, 55131, Germany.
Pulliero A; Department of Health Sciences, University of Genoa, Genoa, 16132, Italy.; Hospital Policlinico San Martino, University of Genoa, Genoa, 16132, Italy.
Izzotti A; Hospital Policlinico San Martino, University of Genoa, Genoa, 16132, Italy.
Laarmann K; Institute of Toxicology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, 40225, Germany.
Fritz G; Institute of Toxicology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, 40225, Germany.
Kaina B; Institute of Toxicology, University Medical Center, Mainz, 55131, Germany. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Sep 24; Vol. 9 (1), pp. 13800. Date of Electronic Publication: 2019 Sep 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Benzo(a)pyrene/*adverse effects
DNA Repair/*drug effects
DNA Repair/*genetics
Endothelial Cells/*drug effects
Human Umbilical Vein Endothelial Cells/*drug effects
Myocytes, Smooth Muscle/*drug effects
Pericytes/*drug effects
Cell Line ; Comet Assay/methods ; DNA/genetics ; DNA Adducts/drug effects ; DNA Adducts/genetics ; DNA Damage/drug effects ; Epoxy Compounds/adverse effects ; Humans ; Mutagens/adverse effects

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 4.

Tytuł:: Dynamic In Vivo Profiling of DNA Damage and Repair after Radiotherapy Using Canine Patients as a Model.
Autorzy:: Schulz N; Division of Radiation Oncology, Vetsuisse Faculty University of Zurich, CH-8057 Zurich, Switzerland. .
Chaachouay H; Division of Radiation Oncology, Vetsuisse Faculty University of Zurich, CH-8057 Zurich, Switzerland. .
Nytko KJ; Division of Radiation Oncology, Vetsuisse Faculty University of Zurich, CH-8057 Zurich, Switzerland. .; Center for Applied Biotechnology and Molecular Medicine (CABMM), University of Zurich, CH-8057 Zurich, Switzerland. .
Weyland MS; ZHAW School of Engineering, Zurich University of Applied Sciences, CH-8400 Winterthur, Switzerland. .
Roos M; Department of Biostatistics, Epidemiology Biostatistics and Prevention Institute, Faculty of Medicine, University of Zurich, CH-8001 Zurich, Switzerland. .
Füchslin RM; ZHAW School of Engineering, Zurich University of Applied Sciences, CH-8400 Winterthur, Switzerland. .
Guscetti F; Institute of Veterinary Pathology, Vetsuisse Faculty University of Zurich, CH-8057 Zurich, Switzerland. .
Scheidegger S; ZHAW School of Engineering, Zurich University of Applied Sciences, CH-8400 Winterthur, Switzerland. .
Rohrer Bley C; Division of Radiation Oncology, Vetsuisse Faculty University of Zurich, CH-8057 Zurich, Switzerland. .; Center for Applied Biotechnology and Molecular Medicine (CABMM), University of Zurich, CH-8057 Zurich, Switzerland. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2017 Jun 01; Vol. 18 (6). Date of Electronic Publication: 2017 Jun 01.
Typ publikacji:: Journal Article
MeSH Terms:: Models, Theoretical*
Radiation, Ionizing*
DNA Damage/*radiation effects
DNA Repair/*radiation effects
Animals ; Comet Assay ; Dogs ; Female ; Histones/metabolism ; Immunohistochemistry ; Kinetics ; Male ; Models, Animal ; Neoplasms/genetics ; Neoplasms/metabolism ; Neoplasms/pathology ; Neoplasms/radiotherapy ; Phosphorylation ; Radiation Dosage ; Radiotherapy

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 5.

Tytuł:: 4-Nonylphenol induced DNA damage and repair in fish, Channa punctatus after subchronic exposure.
Autorzy:: Sharma M; a Department of Zoology , Guru Nanak Dev University , Amritsar , Punjab , India.
Chadha P; a Department of Zoology , Guru Nanak Dev University , Amritsar , Punjab , India.; Pokaż więcej
Źródło:: Drug and chemical toxicology [Drug Chem Toxicol] 2017 Jul; Vol. 40 (3), pp. 320-325. Date of Electronic Publication: 2016 Sep 01.
Typ publikacji:: Journal Article
MeSH Terms:: DNA Damage*
DNA Repair*
Fishes/*genetics
Mutagens/*toxicity
Phenols/*toxicity
Water Pollutants, Chemical/*toxicity
Animals ; Blood Cells/drug effects ; Blood Cells/pathology ; Comet Assay ; Dose-Response Relationship, Drug ; Fishes/blood ; Lethal Dose 50 ; Micronuclei, Chromosome-Defective/chemically induced ; Micronucleus Tests ; Time Factors

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 6.

Tytuł:: The functional status of DNA repair pathways determines the sensitization effect to cisplatin in non-small cell lung cancer cells.
Autorzy:: Chen P; Department of Pulmonary Medicine, Affiliated Hospital of Jiangsu University, 438 North Jiefang Street, Zhenjiang, 212001, China.
Li J; Department of Pulmonary Medicine, Affiliated Hospital of Jiangsu University, 438 North Jiefang Street, Zhenjiang, 212001, China. .
Chen YC; Institute of Medical Science, Jiangsu University, Zhenjiang, 212013, China.
Qian H; Institute of Medical Science, Jiangsu University, Zhenjiang, 212013, China.
Chen YJ; Department of Pulmonary Medicine, Affiliated Hospital of Jiangsu University, 438 North Jiefang Street, Zhenjiang, 212001, China.
Su JY; Department of Pulmonary Medicine, Affiliated Hospital of Jiangsu University, 438 North Jiefang Street, Zhenjiang, 212001, China.
Wu M; Institute of Medical Science, Jiangsu University, Zhenjiang, 212013, China.
Lan T; Institute of Medical Science, Jiangsu University, Zhenjiang, 212013, China.; Pokaż więcej
Źródło:: Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2016 Dec; Vol. 39 (6), pp. 511-522. Date of Electronic Publication: 2016 Jul 29.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Non-Small-Cell Lung/*genetics
DNA Repair/*genetics
Drug Resistance, Neoplasm/*genetics
Lung Neoplasms/*genetics
Antineoplastic Agents/therapeutic use ; Blotting, Western ; Cell Line, Tumor ; Cisplatin/therapeutic use ; Comet Assay ; Flow Cytometry ; Fluorescent Antibody Technique ; Gene Knockdown Techniques ; Humans ; Lung Neoplasms/drug therapy ; Real-Time Polymerase Chain Reaction ; Signal Transduction/physiology

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 7.

Tytuł:: Phosphorylation of H2A.X positively regulates DNA damage response and is linked to cancer progression.
Autorzy:: Liu Y; College of Life Science, North China University of Science and Technology, Tangshan, China.; Cancer Institute, Affiliated Tangshan People's Hospital of North China University of Science and Technology, Tangshan, China.
Long YH; College of Life Science, North China University of Science and Technology, Tangshan, China.
Wang SQ; Hospital of North China University of Science and Technology, Tangshan, China.
Li YF; Cancer Institute, Affiliated Tangshan People's Hospital of North China University of Science and Technology, Tangshan, China.
Zhang JH; Cancer Institute, Affiliated Tangshan People's Hospital of North China University of Science and Technology, Tangshan, China.; Pokaż więcej
Źródło:: The FEBS journal [FEBS J] 2016 Dec; Vol. 283 (24), pp. 4462-4473. Date of Electronic Publication: 2016 Nov 23.
Typ publikacji:: Journal Article
MeSH Terms:: DNA Breaks, Double-Stranded*
DNA Repair*
Histones/*metabolism
Neoplasms/*genetics
Tyrosine/*metabolism
Amino Acid Sequence ; Blotting, Western ; Cell Line, Tumor ; Cell Proliferation/genetics ; Comet Assay ; Disease Progression ; Hep G2 Cells ; Histones/genetics ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; MCF-7 Cells ; Mutation ; Neoplasms/metabolism ; Neoplasms/pathology ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Phosphorylation ; Protein Tyrosine Phosphatases/genetics ; Protein Tyrosine Phosphatases/metabolism ; RNA Interference ; Sequence Homology, Amino Acid ; Tyrosine/genetics

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 8.

Tytuł:: The Architectural Chromatin Factor High Mobility Group A1 Enhances DNA Ligase IV Activity Influencing DNA Repair.
Autorzy:: Pellarin I; Department of Life Sciences, University of Trieste, Trieste, Italy.
Arnoldo L; Department of Life Sciences, University of Trieste, Trieste, Italy.
Costantini S; International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
Pegoraro S; Department of Life Sciences, University of Trieste, Trieste, Italy.
Ros G; Department of Life Sciences, University of Trieste, Trieste, Italy.
Penzo C; Department of Life Sciences, University of Trieste, Trieste, Italy.
Triolo G; International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
Demarchi F; Laboratorio Nazionale Consorzio Interuniversitario Biotecnologie (LNCIB), AREA Science Park, Trieste, Italy.
Sgarra R; Department of Life Sciences, University of Trieste, Trieste, Italy.
Vindigni A; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, Missouri, United States of America.
Manfioletti G; Department of Life Sciences, University of Trieste, Trieste, Italy.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2016 Oct 10; Vol. 11 (10), pp. e0164258. Date of Electronic Publication: 2016 Oct 10 (Print Publication: 2016).
Typ publikacji:: Journal Article
MeSH Terms:: DNA Repair*
Chromatin/*chemistry
DNA Ligase ATP/*metabolism
HMGA1a Protein/*metabolism
Cell Line, Tumor ; Chromatin/metabolism ; Chromatography, High Pressure Liquid ; Comet Assay ; HMGA1a Protein/genetics ; HMGA2 Protein/genetics ; HMGA2 Protein/metabolism ; Histones/metabolism ; Humans ; Ku Autoantigen/metabolism ; MCF-7 Cells ; Microscopy, Fluorescence ; Phosphorylation ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/chemistry ; Recombinant Proteins/isolation & purification ; Substrate Specificity

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 9.

Tytuł:: Influence of Human p53 on Plant Development.
Autorzy:: Ma H; Development Center of Plant Germplasm Resources, College of Life and Environmental Sciences, Shanghai Normal University, Shanghai 200234, China.
Song T; Development Center of Plant Germplasm Resources, College of Life and Environmental Sciences, Shanghai Normal University, Shanghai 200234, China.
Wang T; Development Center of Plant Germplasm Resources, College of Life and Environmental Sciences, Shanghai Normal University, Shanghai 200234, China.
Wang S; Development Center of Plant Germplasm Resources, College of Life and Environmental Sciences, Shanghai Normal University, Shanghai 200234, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2016 Sep 20; Vol. 11 (9), pp. e0162840. Date of Electronic Publication: 2016 Sep 20 (Print Publication: 2016).
Typ publikacji:: Journal Article
MeSH Terms:: Arabidopsis/*genetics
Arabidopsis Proteins/*genetics
DNA Repair/*genetics
Nuclear Proteins/*genetics
Tumor Suppressor Protein p53/*genetics
Arabidopsis/growth & development ; Arabidopsis/metabolism ; Arabidopsis Proteins/metabolism ; Cell Line, Tumor ; Cell Survival/genetics ; Comet Assay ; DNA Damage ; Gene Expression Profiling/methods ; Gene Expression Regulation, Plant ; Homologous Recombination ; Humans ; Immunoblotting ; Inflorescence/genetics ; Inflorescence/growth & development ; Inflorescence/metabolism ; Nuclear Proteins/metabolism ; Osteosarcoma/genetics ; Osteosarcoma/metabolism ; Osteosarcoma/pathology ; Plants, Genetically Modified ; Recombination, Genetic ; Reverse Transcriptase Polymerase Chain Reaction ; Species Specificity ; Transfection ; Tumor Suppressor Protein p53/metabolism

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 10.

Tytuł:: Chronic Alcohol Exposure Decreases 53BP1 Protein Levels Leading to a Defective DNA Repair in Cultured Primary Cortical Neurons.
Autorzy:: Romero AM; Sección de Biología y Patología Celular, Centro de Investigación, Hospital La Fe, Valencia, Spain.; Unidad de Microscopía IIS La Fe, Valencia, Spain.
Palanca A; Department of Anatomy and Cell Biology and 'Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED)', University of Cantabria-IDIVAL, Av. Cardenal Herrera Oria s/n, 39011, Santander, Spain.
Ruiz-Soto M; Department of Anatomy and Cell Biology and 'Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED)', University of Cantabria-IDIVAL, Av. Cardenal Herrera Oria s/n, 39011, Santander, Spain.
Llorca J; Division of Epidemiology and Public Health, 'CIBER de Epidemiología y Salud Pública (CIBERESP)', IDIVAL, University of Cantabria, Santander, Spain.
Marín MP; Unidad de Microscopía IIS La Fe, Valencia, Spain.
Renau-Piqueras J; Sección de Biología y Patología Celular, Centro de Investigación, Hospital La Fe, Valencia, Spain.
Berciano MT; Department of Anatomy and Cell Biology and 'Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED)', University of Cantabria-IDIVAL, Av. Cardenal Herrera Oria s/n, 39011, Santander, Spain.
Lafarga M; Department of Anatomy and Cell Biology and 'Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED)', University of Cantabria-IDIVAL, Av. Cardenal Herrera Oria s/n, 39011, Santander, Spain. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2016 Jan; Vol. 29 (1), pp. 69-79. Date of Electronic Publication: 2015 Aug 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Central Nervous System Depressants/*pharmacology
Cerebral Cortex/*cytology
DNA Repair/*drug effects
Ethanol/*pharmacology
Intracellular Signaling Peptides and Proteins/*metabolism
Neurons/*drug effects
Animals ; Chromatin/drug effects ; Chromatin/ultrastructure ; Comet Assay ; DNA Damage/drug effects ; Dose-Response Relationship, Drug ; Embryo, Mammalian ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/radiation effects ; Hippocampus/cytology ; Histones/metabolism ; Microtubule-Associated Proteins/metabolism ; Neurons/ultrastructure ; Rats ; Time Factors ; Transcriptional Activation/drug effects ; X-Rays/adverse effects

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 11.

Tytuł:: DNA damage measured by comet assay and 8-OH-dG formation related to blood chemical analyses in aged rats.
Autorzy:: Hashimoto K; Department of Applied Veterinary Science, The Doctoral Course of the United Graduate School of Veterinary Science,Gifu University, 1-1 Yanagito, Gifu 501-1112, Japan. />Takasaki W
Sato I
Tsuda S; Pokaż więcej
Źródło:: The Journal of toxicological sciences [J Toxicol Sci] 2007 Aug; Vol. 32 (3), pp. 249-59.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Blood Chemical Analysis*
Comet Assay*
DNA Damage*
DNA Repair*/drug effects
Aging/*genetics
Deoxyguanosine/*analogs & derivatives
Kidney/*metabolism
Liver/*metabolism
8-Hydroxy-2'-Deoxyguanosine ; Aging/blood ; Aging/metabolism ; Animals ; DNA Adducts/metabolism ; Deoxyguanosine/metabolism ; Diethylnitrosamine/toxicity ; Hydrogen-Ion Concentration ; Kidney/drug effects ; Liver/drug effects ; Male ; Methyl Methanesulfonate/toxicity ; Mutagens/toxicity ; Rats ; Rats, Inbred F344 ; Reactive Oxygen Species/metabolism ; Time Factors

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 12.

Tytuł:: IL-6 signaling promotes DNA repair and prevents apoptosis in CD133+ stem-like cells of lung cancer after radiation.
Autorzy:: Chen Y; Department of Radiation Oncology, James P. Wilmot Cancer Center, University of Rochester, 601 Elmwood Ave., Box 647, Rochester, NY, 14642, USA. yuhchyau_.
Zhang F; Department of Radiation Oncology, James P. Wilmot Cancer Center, University of Rochester, 601 Elmwood Ave., Box 647, Rochester, NY, 14642, USA. fuquan_.
Tsai Y; Department of Radiation Oncology, James P. Wilmot Cancer Center, University of Rochester, 601 Elmwood Ave., Box 647, Rochester, NY, 14642, USA. ying_.
Yang X; Department of Radiation Oncology, James P. Wilmot Cancer Center, University of Rochester, 601 Elmwood Ave., Box 647, Rochester, NY, 14642, USA. xiadong_.
Yang L; Department of Radiation Oncology, James P. Wilmot Cancer Center, University of Rochester, 601 Elmwood Ave., Box 647, Rochester, NY, 14642, USA. li_.
Duan S; Department of Radiation Oncology, James P. Wilmot Cancer Center, University of Rochester, 601 Elmwood Ave., Box 647, Rochester, NY, 14642, USA. shanzhou_.
Wang X; Department of Radiation Oncology, James P. Wilmot Cancer Center, University of Rochester, 601 Elmwood Ave., Box 647, Rochester, NY, 14642, USA. xin_.
Keng P; Department of Radiation Oncology, James P. Wilmot Cancer Center, University of Rochester, 601 Elmwood Ave., Box 647, Rochester, NY, 14642, USA. peter_.
Lee SO; Department of Radiation Oncology, James P. Wilmot Cancer Center, University of Rochester, 601 Elmwood Ave., Box 647, Rochester, NY, 14642, USA. soook_.; Pokaż więcej
Źródło:: Radiation oncology (London, England) [Radiat Oncol] 2015 Nov 14; Vol. 10, pp. 227. Date of Electronic Publication: 2015 Nov 14.
Typ publikacji:: Journal Article; Retracted Publication
MeSH Terms:: DNA Repair/*physiology
Interleukin-6/*metabolism
Lung Neoplasms/*pathology
Neoplastic Stem Cells/*pathology
Radiation Tolerance/*physiology
Signal Transduction/*radiation effects
AC133 Antigen ; Antigens, CD/metabolism ; Apoptosis/physiology ; Apoptosis/radiation effects ; Blotting, Western ; Cell Line, Tumor ; Cell Separation ; Comet Assay ; DNA Repair/radiation effects ; Enzyme-Linked Immunosorbent Assay ; Flow Cytometry ; Fluorescent Antibody Technique ; Gene Knockdown Techniques ; Glycoproteins/metabolism ; Humans ; Lung Neoplasms/metabolism ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/radiation effects ; Peptides/metabolism ; RNA, Small Interfering ; Real-Time Polymerase Chain Reaction ; Signal Transduction/physiology ; Transduction, Genetic

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 13.

Tytuł:: Effects of combined physical exercise training on DNA damage and repair capacity: role of oxidative stress changes.
Autorzy:: Soares JP; Research Center in Sports Sciences, Health and Human Development (CIDESD), University of Trás-os-Montes e Alto Douro (UTAD), Quinta dos Prados, P-5001-801, Vila Real, Portugal, .
Silva AM
Oliveira MM
Peixoto F
Gaivão I
Mota MP; Pokaż więcej
Źródło:: Age (Dordrecht, Netherlands) [Age (Dordr)] 2015 Jun; Vol. 37 (3), pp. 9799. Date of Electronic Publication: 2015 Jun 05.
Typ publikacji:: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:: Physical Education and Training*
Aging/*blood
Antioxidants/*metabolism
DNA Damage/*physiology
DNA Repair/*physiology
Lymphocytes/*metabolism
Oxidative Stress/*physiology
Adult ; Aged ; Anthropometry ; Biomarkers/blood ; Comet Assay ; Humans ; Lipid Peroxidation/physiology ; Male ; Malondialdehyde/blood ; Middle Aged

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 14.

Tytuł:: Reptin regulates DNA double strand breaks repair in human hepatocellular carcinoma.
Autorzy:: Raymond AA; INSERM, U1053, F-33076 Bordeaux, France; Université de Bordeaux, F 33076, Bordeaux, France.
Benhamouche S; INSERM, U1053, F-33076 Bordeaux, France; Université de Bordeaux, F 33076, Bordeaux, France.
Neaud V; INSERM, U1053, F-33076 Bordeaux, France; Université de Bordeaux, F 33076, Bordeaux, France.
Di Martino J; INSERM, U1053, F-33076 Bordeaux, France; Université de Bordeaux, F 33076, Bordeaux, France.
Javary J; INSERM, U1053, F-33076 Bordeaux, France; Université de Bordeaux, F 33076, Bordeaux, France.
Rosenbaum J; INSERM, U1053, F-33076 Bordeaux, France; Université de Bordeaux, F 33076, Bordeaux, France.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2015 Apr 15; Vol. 10 (4), pp. e0123333. Date of Electronic Publication: 2015 Apr 15 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Breaks, Double-Stranded*
RNA Interference*
Carrier Proteins/*genetics
DNA Helicases/*genetics
DNA Repair/*genetics
ATPases Associated with Diverse Cellular Activities ; Antineoplastic Agents, Phytogenic/pharmacology ; Ataxia Telangiectasia Mutated Proteins/genetics ; Ataxia Telangiectasia Mutated Proteins/metabolism ; Blotting, Western ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/pathology ; Carrier Proteins/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Cell Proliferation/radiation effects ; Comet Assay ; DNA Helicases/metabolism ; DNA-Activated Protein Kinase/genetics ; DNA-Activated Protein Kinase/metabolism ; Etoposide/pharmacology ; Gamma Rays ; Histones/metabolism ; Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Microscopy, Confocal ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Phosphorylation/drug effects ; Phosphorylation/radiation effects ; Protein Binding ; Reverse Transcriptase Polymerase Chain Reaction

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 15.

Tytuł:: Growth hormone protects colorectal cancer cells from radiation by improving the ability of DNA damage repair.
Autorzy:: Wu XY; Department of Gastrointestinal Tumor Surgery, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu 210029, P.R. China.
Chen C; Department of Gastrointestinal Tumor Surgery, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu 210029, P.R. China.
Yao XQ; Department of Gastrointestinal Tumor Surgery, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu 210029, P.R. China.
Cao QH; Department of Gastrointestinal Tumor Surgery, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu 210029, P.R. China.
Xu Z; Department of Gastrointestinal Tumor Surgery, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu 210029, P.R. China.
Li WS; Department of Gastrointestinal Tumor Surgery, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu 210029, P.R. China.
Liu FK; Department of Gastrointestinal Tumor Surgery, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu 210029, P.R. China.
Li G; Department of General Surgery, Jiangsu Cancer Hospital, Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, Jiangsu 210009, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2014 Jul; Vol. 10 (1), pp. 486-90. Date of Electronic Publication: 2014 Apr 24.
Typ publikacji:: Journal Article
MeSH Terms:: DNA Repair/*drug effects
Growth Hormone/*pharmacology
Carrier Proteins/antagonists & inhibitors ; Carrier Proteins/metabolism ; Cell Line, Tumor ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; Colorectal Neoplasms/radiotherapy ; Comet Assay ; DNA Damage/radiation effects ; DNA-(Apurinic or Apyrimidinic Site) Lyase/metabolism ; Gamma Rays ; Growth Hormone/genetics ; Growth Hormone/metabolism ; HT29 Cells ; Humans ; Intracellular Signaling Peptides and Proteins/metabolism ; GADD45 Proteins

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 16.

Tytuł:: Lithium increases radiosensitivity by abrogating DNA repair in breast cancer spheroid culture.
Autorzy:: Rouhani M; Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran. .
Goliaei B; Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
Khodagholi F; Neurobiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nikoofar A; Department of Radiotherapy, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.; Pokaż więcej
Źródło:: Archives of Iranian medicine [Arch Iran Med] 2014 May; Vol. 17 (5), pp. 352-60.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Breast Neoplasms/*radiotherapy
DNA Repair/*drug effects
Lithium Chloride/*pharmacology
Radiation-Sensitizing Agents/*pharmacology
Apoptosis ; Blotting, Western ; Cell Line, Tumor ; Cell Survival/drug effects ; Comet Assay ; Dose-Response Relationship, Drug ; Female ; Humans ; Microscopy, Fluorescence ; Spheroids, Cellular/drug effects

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 17.

Tytuł:: Assessment of genomic damage and repair on human lymphocytes by paint thinner in vitro.
Autorzy:: Londoño-Velasco E; Department of Biology, Research Group Genetic Toxicology and Cytogenetics, Faculty of Natural Sciences and Education, Universidad del Cauca, Popayán , Cauca , Colombia and.
Hidalgo-Cerón V
Escobar-Hoyos LF
Hoyos-Giraldo LS; Pokaż więcej
Źródło:: Toxicology mechanisms and methods [Toxicol Mech Methods] 2014 May; Vol. 24 (4), pp. 243-9.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Repair*
Lymphocytes/*drug effects
Solvents/*toxicity
Comet Assay ; Humans ; In Vitro Techniques ; Lymphocytes/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 18.

Tytuł:: X-ray induced DNA damage and repair in germ cells of PARP1(-/-) male mice.
Autorzy:: Villani P; Unit of Radiation Biology and Human Health, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, CR Casaccia, Via Anguillarese 301, Roma 00123, Italy. />Fresegna AM
Ranaldi R
Eleuteri P
Paris L
Pacchierotti F
Cordelli E; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2013 Sep 04; Vol. 14 (9), pp. 18078-92. Date of Electronic Publication: 2013 Sep 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Damage/*radiation effects
DNA Repair/*radiation effects
Germ Cells/*metabolism
Germ Cells/*radiation effects
Poly(ADP-ribose) Polymerases/*metabolism
X-Rays/*adverse effects
Animals ; Comet Assay ; Flow Cytometry ; Histones ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Phosphorylation ; Poly (ADP-Ribose) Polymerase-1 ; Poly(ADP-ribose) Polymerases/genetics

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 19.

Tytuł:: Single cell analysis of human RAD18-dependent DNA post-replication repair by alkaline bromodeoxyuridine comet assay.
Autorzy:: Mórocz M; Institute of Genetics, Biological Research Centre of Hungarian Academy of Sciences, Szeged, Hungary.
Gali H
Raskó I
Downes CS
Haracska L; Pokaż więcej
Źródło:: PloS one [PLoS One] 2013 Aug 06; Vol. 8 (8), pp. e70391. Date of Electronic Publication: 2013 Aug 06 (Print Publication: 2013).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Repair*/radiation effects
DNA Replication*/radiation effects
Comet Assay/*methods
DNA/*biosynthesis
DNA/*genetics
DNA-Binding Proteins/*metabolism
Single-Cell Analysis/*methods
Bromodeoxyuridine/metabolism ; DNA Damage/genetics ; DNA-Binding Proteins/deficiency ; DNA-Binding Proteins/genetics ; Dose-Response Relationship, Radiation ; Gene Knockout Techniques ; HCT116 Cells ; HeLa Cells ; Humans ; Kinetics ; S Phase/genetics ; S Phase/radiation effects ; Ubiquitin-Protein Ligases ; Ultraviolet Rays

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 20.

Tytuł:: Oxidative stress-induced DNA damage and repair in human peripheral blood mononuclear cells: protective role of hemoglobin.
Autorzy:: Gafter-Gvili A; Department of Medicine E, Rabin Medical Center, Petah Tikva, Israel.
Zingerman B
Rozen-Zvi B
Ori Y
Green H
Lubin I
Malachi T
Gafter U
Herman-Edelstein M; Pokaż więcej
Źródło:: PloS one [PLoS One] 2013 Jul 09; Vol. 8 (7), pp. e68341. Date of Electronic Publication: 2013 Jul 09 (Print Publication: 2013).
Typ publikacji:: Journal Article
MeSH Terms:: DNA Damage*/drug effects
DNA Repair*
Oxidative Stress*
Hemoglobins/*metabolism
Leukocytes, Mononuclear/*metabolism
Comet Assay ; DNA/drug effects ; DNA/genetics ; Dose-Response Relationship, Drug ; Erythrocytes/drug effects ; Erythrocytes/metabolism ; Hemolysis/drug effects ; Histones/metabolism ; Humans ; Hydrogen Peroxide/pharmacology ; Phosphorylation

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Informacja

Wyszukujesz frazę ""comet assay"" wg kryterium: Temat

Źródło danych

Ogranicz do:

Ogranicz do bazy

Typ dokumentu

Temat

Wydawca

Publikacja

Język