Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""cytochrome P450."" wg kryterium: Temat


Tytuł:
CYP1-Activation and Anticancer Properties of Synthetic Methoxylated Resveratrol Analogues.
Autorzy:
Ruparelia KC; Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK.
Zeka K; Zayed Centre for Research into Rare Disease in Children, University College London, London WC1E 6BT, UK.
Beresford KJM; Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK.
Wilsher NE; Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK.
Potter GA; Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK.
Androutsopoulos VP; Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK.
Brucoli F; Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK.
Arroo RRJ; Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK.
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Jan 15; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 15.
Typ publikacji:
Journal Article
MeSH Terms:
Cytochrome P-450 CYP1A1*
Cytochrome P450 Family 1*
Humans ; Resveratrol/pharmacology ; Catalysis ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
CYP4V2 rs56413992 C > T was associated with the risk of coronary heart disease in the Chinese Han population: a case-control study.
Autorzy:
Huang K; Department of Cardiology, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, No. 43, Renmin Avenue, Haikou, Hainan, China.
Ma T; Department of Cardiology, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, No. 43, Renmin Avenue, Haikou, Hainan, China.
Li Q; Department of Cardiology, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, No. 43, Renmin Avenue, Haikou, Hainan, China.
Zhong Z; Department of Cardiology, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, No. 43, Renmin Avenue, Haikou, Hainan, China.
Zhou Y; School of Medicine, Jingchu University of Technology, Jingmen, Hubei, China.
Zhang W; Department of Cardiology, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, No. 43, Renmin Avenue, Haikou, Hainan, China.
Qin T; Department of Cardiology, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, No. 43, Renmin Avenue, Haikou, Hainan, China.
Tang S; Department of Cardiology, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, No. 43, Renmin Avenue, Haikou, Hainan, China.
Zhong J; Department of Cardiology, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, No. 43, Renmin Avenue, Haikou, Hainan, China. .
Lu S; Department of Cardiology, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, No. 43, Renmin Avenue, Haikou, Hainan, China. Lu_.
Pokaż więcej
Źródło:
BMC medical genomics [BMC Med Genomics] 2023 Dec 08; Vol. 16 (1), pp. 322. Date of Electronic Publication: 2023 Dec 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Coronary Disease*/genetics
Cytochrome P450 Family 4*/genetics
Genetic Predisposition to Disease*
Humans ; Male ; Case-Control Studies ; China ; Genotype ; Polymorphism, Single Nucleotide ; Risk Factors
Czasopismo naukowe
Tytuł:
Correlation of CYP2R1 gene promoter methylation with circulating vitamin D levels among healthy adults.
Autorzy:
Varadharajan A; Department of Biochemistry, Armed Forces Medical College, Pune, Maharashtra, India.
Sibin MK; Department of Biochemistry, Armed Forces Medical College, Pune, Maharashtra, India.
Athira SV; Department of Biochemistry, Armed Forces Medical College, Pune, Maharashtra, India.
Ghosh AK; Department of Cardiology, Army Institute of Cardio Thoracic Sciences, Pune, Maharashtra, India.
Misra P; Department of Biochemistry, Armed Forces Medical College, Pune, Maharashtra, India.
Pokaż więcej
Źródło:
The Indian journal of medical research [Indian J Med Res] 2023 Aug; Vol. 158 (2), pp. 197-200.
Typ publikacji:
Journal Article
MeSH Terms:
Cholestanetriol 26-Monooxygenase*/genetics
Cholestanetriol 26-Monooxygenase*/metabolism
Cytochrome P450 Family 2*/genetics
Cytochrome P450 Family 2*/metabolism
Vitamin D*/blood
Vitamin D Deficiency*/epidemiology
Vitamin D Deficiency*/genetics
Vitamin D Deficiency*/metabolism
Adult ; Humans ; Calcium/metabolism ; Cross-Sectional Studies ; Methylation ; Pilot Projects ; Polymorphism, Single Nucleotide ; Promoter Regions, Genetic ; Vitamins
Czasopismo naukowe
Tytuł:
25-Hydroxyvitamin D Serum Levels Linked to Single Nucleotide Polymorphisms (SNPs) (rs2228570, rs2282679, rs10741657) in Skeletal Muscle Aging in Institutionalized Elderly Men Not Supplemented with Vitamin D.
Autorzy:
Fernández-Lázaro D; Department of Cellular Biology, Genetics, Histology and Pharmacology, Faculty of Health Sciences, Campus of Soria, University of Valladolid, 42003 Soria, Spain.; Neurobiology Research Group, Faculty of Medicine, University of Valladolid, 47005 Valladolid, Spain.
Hernández JLG; Molecular Mechanisms of Cancer Program, Institute of Molecular and Cellular Biology of Cancer, Spanish National Research Council (CSIC), University of Salamanca, 37007 Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), Department of Hematology, Salamanca University Hospital, 37007 Salamanca, Spain.
Lumbreras E; Institute of Biomedical Research of Salamanca (IBSAL), Cytogenetics-Molecular Genetics in Onco-Hematology, Cancer Research Center-University of Salamanca (IBMCC, USAL-CSIC), 37008 Salamanca, Spain.
Mielgo-Ayuso J; Department of Health Sciences, Faculty of Health Sciences, University of Burgos, 09001 Burgos, Spain.
Seco-Calvo J; Physiotherapy Department, Institute of Biomedicine (IBIOMED), Campus of Vegazana, University of Leon, 24071 Leon, Spain.; Physiology Department, Faculty of Medicine, Basque Country University, 48900 Leioa, Spain.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 06; Vol. 23 (19). Date of Electronic Publication: 2022 Oct 06.
Typ publikacji:
Journal Article
MeSH Terms:
Cholestanetriol 26-Monooxygenase*/genetics
Cytochrome P450 Family 2*/genetics
Receptors, Calcitriol*/genetics
Sarcopenia*/genetics
Vitamin D Deficiency*/genetics
Vitamin D-Binding Protein*/genetics
Aged ; Aging/genetics ; Calcifediol ; Genotype ; Humans ; Male ; Muscle, Skeletal ; Polymorphism, Single Nucleotide ; Vitamin D/analogs & derivatives ; Vitamins
Czasopismo naukowe
Tytuł:
AAV2-mediated gene therapy for Bietti crystalline dystrophy provides functional CYP4V2 in multiple relevant cell models.
Autorzy:
Wang JH; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Level 7, 32 Gisborne Street, East Melbourne, VIC, 3002, Australia.
Lidgerwood GE; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Level 7, 32 Gisborne Street, East Melbourne, VIC, 3002, Australia.; Department of Anatomy and Physiology, The University of Melbourne, Parkville, Australia.
Daniszewski M; Department of Anatomy and Physiology, The University of Melbourne, Parkville, Australia.
Hu ML; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Level 7, 32 Gisborne Street, East Melbourne, VIC, 3002, Australia.
Roberts GE; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Level 7, 32 Gisborne Street, East Melbourne, VIC, 3002, Australia.
Wong RCB; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Level 7, 32 Gisborne Street, East Melbourne, VIC, 3002, Australia.; Ophthalmology, Department of Surgery, The University of Melbourne, East Melbourne, VIC, Australia.; Shenzhen Eye Hospital, Shenzhen University School of Medicine, Shenzhen, China.
Hung SSC; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Level 7, 32 Gisborne Street, East Melbourne, VIC, 3002, Australia.; Ophthalmology, Department of Surgery, The University of Melbourne, East Melbourne, VIC, Australia.
McClements ME; Department of Clinical Neurosciences, Nuffield Laboratory of Ophthalmology, University of Oxford, Oxford, UK.
Hewitt AW; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Level 7, 32 Gisborne Street, East Melbourne, VIC, 3002, Australia.; Ophthalmology, Department of Surgery, The University of Melbourne, East Melbourne, VIC, Australia.; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia.
Pébay A; Department of Anatomy and Physiology, The University of Melbourne, Parkville, Australia.; Department of Surgery, Royal Melbourne Hospital, The University of Melbourne, Parkville, Australia.
Hickey DG; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Level 7, 32 Gisborne Street, East Melbourne, VIC, 3002, Australia.
Edwards TL; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Level 7, 32 Gisborne Street, East Melbourne, VIC, 3002, Australia. .; Ophthalmology, Department of Surgery, The University of Melbourne, East Melbourne, VIC, Australia. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2022 Jun 09; Vol. 12 (1), pp. 9525. Date of Electronic Publication: 2022 Jun 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Corneal Dystrophies, Hereditary*/genetics
Corneal Dystrophies, Hereditary*/therapy
Cytochrome P450 Family 4*/genetics
Genetic Therapy*
Retinal Diseases*/genetics
Retinal Diseases*/therapy
DNA Mutational Analysis ; HEK293 Cells ; Humans ; Mutation
SCR Disease Name:
Bietti Crystalline Dystrophy
Czasopismo naukowe
Tytuł:
Genetic variants of vitamin D metabolism-related DHCR7/NADSYN1 locus and CYP2R1 gene are associated with clinical features of Parkinson's disease.
Autorzy:
Alaylıoğlu M; Brain and Neurodegenerative Disorders Research Laboratory, Department of Medical Biology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Dursun E; Brain and Neurodegenerative Disorders Research Laboratory, Department of Medical Biology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.; Department of Neuroscience, Institute of Neurological Sciences, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Genç G; Department of Neurology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.
Şengül B; Brain and Neurodegenerative Disorders Research Laboratory, Department of Medical Biology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Bilgiç B; Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Gündüz A; Department of Neurology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Apaydın H; Department of Neurology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Kızıltan G; Department of Neurology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Gürvit H; Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Hanağası H; Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Öztop Çakmak Ö; Department of Neurology, Koc University Hospital, Istanbul, Turkey.
Ertan S; Department of Neurology, Koc University Hospital, Istanbul, Turkey.
Yılmazer S; Department of Medical Biology, Altinbas University, Istanbul, Turkey.
Gezen-Ak D; Brain and Neurodegenerative Disorders Research Laboratory, Department of Medical Biology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Pokaż więcej
Źródło:
The International journal of neuroscience [Int J Neurosci] 2022 May; Vol. 132 (5), pp. 439-449. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji:
Journal Article
MeSH Terms:
Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor*/genetics
Cholestanetriol 26-Monooxygenase*/genetics
Cytochrome P450 Family 2*/genetics
Oxidoreductases Acting on CH-CH Group Donors*/genetics
Parkinson Disease*/genetics
Vitamin D*/metabolism
Gait Disorders, Neurologic/genetics ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Humans ; Polymorphism, Single Nucleotide ; Vitamin D Deficiency
Czasopismo naukowe
Tytuł:
Investigation of the inhibition of eight major human cytochrome P450 isozymes by a probe substrate cocktail in vitro with emphasis on CYP2E1.
Autorzy:
Valicherla GR; Department of Drug Metabolism and Pharmacokinetics, Biology Division, GVK Biosciences Pvt. Ltd , Hyderabad , India.
Mishra A; Department of Drug Metabolism and Pharmacokinetics, Biology Division, GVK Biosciences Pvt. Ltd , Hyderabad , India.
Lenkalapelly S; Department of Drug Metabolism and Pharmacokinetics, Biology Division, GVK Biosciences Pvt. Ltd , Hyderabad , India.
Jillela B; Department of Drug Metabolism and Pharmacokinetics, Biology Division, GVK Biosciences Pvt. Ltd , Hyderabad , India.
Francis FM; Department of Drug Metabolism and Pharmacokinetics, Biology Division, GVK Biosciences Pvt. Ltd , Hyderabad , India.
Rajagopalan L; Department of Drug Metabolism and Pharmacokinetics, Biology Division, GVK Biosciences Pvt. Ltd , Hyderabad , India.
Srivastava P; Department of Drug Metabolism and Pharmacokinetics, Biology Division, GVK Biosciences Pvt. Ltd , Hyderabad , India.
Pokaż więcej
Źródło:
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2019 Dec; Vol. 49 (12), pp. 1396-1402. Date of Electronic Publication: 2019 Jun 19.
Typ publikacji:
Journal Article; Video-Audio Media
MeSH Terms:
Cytochrome P-450 Enzyme Inhibitors/*pharmacology
Cytochrome P450 Family 2/*metabolism
Drug Evaluation, Preclinical/*methods
Chromatography, Liquid ; Cytochrome P450 Family 2/antagonists & inhibitors ; Cytochrome P450 Family 3/antagonists & inhibitors ; Cytochrome P450 Family 3/metabolism ; Dimethyl Sulfoxide/pharmacology ; Humans ; Microsomes, Liver/drug effects ; Microsomes, Liver/enzymology ; Reproducibility of Results ; Substrate Specificity ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł:
New Variants of the Cytochrome P450 2R1 ( CYP2R1 ) Gene in Individuals with Severe Vitamin D-Activating Enzyme 25(OH)D Deficiency.
Autorzy:
Fronczek M; Department of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland.; Department of Pharmacology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland.
Strzelczyk JK; Department of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland.
Biernacki K; Department of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland.
Salatino S; Molecular Biology, Core Research Laboratories, Natural History Museum, London SW7 5BD, UK.
Osadnik T; Department of Pharmacology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland.
Ostrowska Z; Department of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland.
Pokaż więcej
Źródło:
Biomolecules [Biomolecules] 2021 Dec 12; Vol. 11 (12). Date of Electronic Publication: 2021 Dec 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amino Acid Substitution*
Cholestanetriol 26-Monooxygenase/*genetics
Cytochrome P450 Family 2/*genetics
Sequence Analysis, DNA/*methods
Vitamin D Deficiency/*genetics
Adult ; Binding Sites ; Case-Control Studies ; Cholestanetriol 26-Monooxygenase/chemistry ; Cholestanetriol 26-Monooxygenase/metabolism ; Cytochrome P450 Family 2/chemistry ; Cytochrome P450 Family 2/metabolism ; Female ; Humans ; Male ; Vitamin D/analogs & derivatives ; Vitamin D/blood ; Vitamin D Deficiency/blood ; Young Adult
Czasopismo naukowe
Tytuł:
CRISPR/Cas9-mediated activation of NR5A1 steers female human embryonic stem cell-derived bipotential gonadal-like cells towards a steroidogenic cell fate.
Autorzy:
Danti L; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, 00290, Finland.
Lundin K; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, 00290, Finland.
Sepponen K; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, 00290, Finland.
Yohannes DA; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, 00290, Finland.; Research Programs Unit, Translational Immunology & Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, 00290, Finland.
Kere J; Folkhälsan Research Centre, Stem Cells and Metabolism Research Program, University of Helsinki, Helsinki, 00290, Finland.; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, 14183, Sweden.
Tuuri T; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, 00290, Finland.
Tapanainen JS; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, 00290, Finland. .; Department of Obstetrics and Gynecology, HFR - Cantonal Hospital of Fribourg and University of Fribourg, Fribourg, 1708, Switzerland. .
Pokaż więcej
Źródło:
Journal of ovarian research [J Ovarian Res] 2023 Sep 20; Vol. 16 (1), pp. 194. Date of Electronic Publication: 2023 Sep 20.
Typ publikacji:
Journal Article
MeSH Terms:
Human Embryonic Stem Cells*
Animals ; Humans ; Female ; Male ; CRISPR-Cas Systems ; Steroidogenic Factor 1/genetics ; Cell Differentiation/genetics ; Cytochrome P450 Family 17
Czasopismo naukowe
Tytuł:
Posttranslational Modification of Human Cytochrome CYP4F11 by 4-Hydroxynonenal Impairs ω-Hydroxylation in Malaria Pigment Hemozoin-Fed Monocytes: The Role in Malaria Immunosuppression.
Autorzy:
Skorokhod O; Department of Life Sciences and Systems Biology, University of Torino, 10123 Torino, Italy.
Triglione V; Department of Life Sciences and Systems Biology, University of Torino, 10123 Torino, Italy.
Barrera V; Department of Oncology, University of Torino, 10126 Torino, Italy.; Department of Eye and Vision Science, University of Liverpool, Liverpool L7 8TX, UK.
Di Nardo G; Department of Life Sciences and Systems Biology, University of Torino, 10123 Torino, Italy.
Valente E; Department of Oncology, University of Torino, 10126 Torino, Italy.
Ulliers D; Department of Oncology, University of Torino, 10126 Torino, Italy.
Schwarzer E; Department of Oncology, University of Torino, 10126 Torino, Italy.
Gilardi G; Department of Life Sciences and Systems Biology, University of Torino, 10123 Torino, Italy.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 16; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 16.
Typ publikacji:
Journal Article
MeSH Terms:
Monocytes*/metabolism
Malaria*/metabolism
Humans ; Hydroxylation ; Gas Chromatography-Mass Spectrometry ; Immunosuppression Therapy ; Protein Processing, Post-Translational ; Cytochrome P450 Family 4/metabolism
Czasopismo naukowe
Tytuł:
Oxysterol 7-α Hydroxylase (CYP7B1) Attenuates Metabolic-Associated Fatty Liver Disease in Mice at Thermoneutrality.
Autorzy:
Evangelakos I; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Schwinge D; Department of Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Worthmann A; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
John C; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Roeder N; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Pertzborn P; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Behrens J; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Schramm C; Department of Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Scheja L; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Heeren J; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Pokaż więcej
Źródło:
Cells [Cells] 2021 Oct 05; Vol. 10 (10). Date of Electronic Publication: 2021 Oct 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Temperature*
Cytochrome P450 Family 7/*metabolism
Fatty Liver/*enzymology
Fatty Liver/*metabolism
Steroid Hydroxylases/*metabolism
Animals ; Biomarkers/metabolism ; Cytochrome P450 Family 7/deficiency ; Inflammation/pathology ; Lipid Metabolism ; Liver/metabolism ; Liver/pathology ; Liver Cirrhosis/metabolism ; Liver Cirrhosis/pathology ; Mice ; Mice, Knockout ; Phenotype ; Receptors, Lipoprotein/metabolism ; Spleen/immunology ; Steroid Hydroxylases/deficiency ; Up-Regulation
Czasopismo naukowe
Tytuł:
Cytochrome P450 isoforms 1A1, 1B1 AND 2W1 as targets for therapeutic intervention in head and neck cancer.
Autorzy:
Presa D; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
Khurram SA; Unit of Oral and Maxillofacial Pathology, School of Clinical Dentistry, 19 Claremont Crescent, Sheffield, S10 2TA, UK.
Zubir AZA; Unit of Oral and Maxillofacial Pathology, School of Clinical Dentistry, 19 Claremont Crescent, Sheffield, S10 2TA, UK.
Smarakan S; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
Cooper PA; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
Morais GR; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
Sadiq M; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
Sutherland M; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
Loadman PM; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
McCaul J; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.; Regional Maxillofacial Unit, Queen Elizabeth University Hospital, 1345 Govan Road, Glasgow, G51 4TF, UK.
Shnyder SD; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
Patterson LH; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
Pors K; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2021 Sep 23; Vol. 11 (1), pp. 18930. Date of Electronic Publication: 2021 Sep 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*pharmacology
Cytochrome P-450 CYP1A1/*antagonists & inhibitors
Cytochrome P-450 CYP1B1/*antagonists & inhibitors
Cytochrome P450 Family 2/*antagonists & inhibitors
Head and Neck Neoplasms/*drug therapy
Animals ; Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; Cohort Studies ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 CYP1B1/metabolism ; Cytochrome P450 Family 2/metabolism ; Female ; Head and Neck Neoplasms/pathology ; Heterocyclic Compounds, 3-Ring/pharmacology ; Heterocyclic Compounds, 3-Ring/therapeutic use ; Humans ; Indoles/pharmacology ; Indoles/therapeutic use ; Mice ; Prodrugs/pharmacology ; Prodrugs/therapeutic use ; Pyrroles/pharmacology ; Pyrroles/therapeutic use ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
Cyp2c44 epoxygenase-derived epoxyeicosatrienoic acids in vascular smooth muscle cells elicit vasoconstriction of the murine ophthalmic artery.
Autorzy:
Hu J; Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt, Germany.; German Centre of Cardiovascular Research (DZHK), Partner site RheinMain, Frankfurt, Germany.
Sisignano M; Pharmazentrum Frankfurt/ZAFES, Institute of Clinical Pharmacology, University Hospital, Goethe-University, Frankfurt, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt, Germany.
Brecht R; Department of Ophthalmology, University Medical Centre of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
Perumal N; Department of Ophthalmology, University Medical Centre of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
Angioni C; Pharmazentrum Frankfurt/ZAFES, Institute of Clinical Pharmacology, University Hospital, Goethe-University, Frankfurt, Germany.
Bibli IS; Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt, Germany.; German Centre of Cardiovascular Research (DZHK), Partner site RheinMain, Frankfurt, Germany.
Fisslthaler B; Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt, Germany.; German Centre of Cardiovascular Research (DZHK), Partner site RheinMain, Frankfurt, Germany.
Kleinert H; Department of Pharmacology, University Medical Centre of the Johannes Gutenberg University Mainz, Mainz, Germany.
Pfeiffer N; Department of Ophthalmology, University Medical Centre of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
Fleming I; Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt, Germany.; German Centre of Cardiovascular Research (DZHK), Partner site RheinMain, Frankfurt, Germany.
Manicam C; Department of Ophthalmology, University Medical Centre of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2021 Sep 21; Vol. 11 (1), pp. 18764. Date of Electronic Publication: 2021 Sep 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cytochrome P450 Family 2/*chemistry
Fatty Acids, Monounsaturated/*pharmacology
Ophthalmic Artery/*drug effects
Vasoconstriction/*drug effects
Animals ; Cytochrome P450 Family 2/metabolism ; Epoxide Hydrolases/metabolism ; Fatty Acids, Monounsaturated/chemistry ; Mice ; Ophthalmic Artery/enzymology ; Ophthalmic Artery/physiology
Czasopismo naukowe
Tytuł:
Computational analysis of missense variant CYP4F2*3 (V433M) in association with human CYP4F2 dysfunction: a functional and structural impact.
Autorzy:
Farajzadeh-Dehkordi M; Department of Molecular Medicine, Faculty of Medical School, Qazvin University of Medical Sciences, Qazvin, Iran.
Mafakher L; Thalassemia & Hemoglobinopathy Research center, Health research institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. .; Department of Pathology, Faculty of Medical School, Qazvin University of Medical Sciences, Qazvin, Iran. .
Samiee-Rad F; Department of Pathology, Faculty of Medical School, Qazvin University of Medical Sciences, Qazvin, Iran.
Rahmani B; Department of Molecular Medicine, Faculty of Medical School, Qazvin University of Medical Sciences, Qazvin, Iran. .
Pokaż więcej
Źródło:
BMC molecular and cell biology [BMC Mol Cell Biol] 2023 May 09; Vol. 24 (1), pp. 17. Date of Electronic Publication: 2023 May 09.
Typ publikacji:
Journal Article
MeSH Terms:
Vitamin K 1*
Cytochrome P-450 Enzyme System*/genetics
Humans ; Molecular Docking Simulation ; Cytochrome P450 Family 4/genetics ; Molecular Dynamics Simulation
Czasopismo naukowe
Tytuł:
Wolbachia enhances expression of NlCYP4CE1 in Nilaparvata lugens in response to imidacloprid stress.
Autorzy:
Cai T; Hubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, China.
Zhang Y; Hubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, China.
Liu Y; Hubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, China.
Deng X; Hubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, China.
He S; Hubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, China.
Li J; Hubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, China.
Wan H; Hubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, China.
Pokaż więcej
Źródło:
Insect science [Insect Sci] 2021 Apr; Vol. 28 (2), pp. 355-362. Date of Electronic Publication: 2020 Jul 21.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression*
Cytochrome P450 Family 4/*genetics
Hemiptera/*drug effects
Insect Proteins/*genetics
Insecticides/*pharmacology
Neonicotinoids/*pharmacology
Nitro Compounds/*pharmacology
Wolbachia/*physiology
Animals ; Cytochrome P450 Family 4/metabolism ; Hemiptera/genetics ; Hemiptera/growth & development ; Hemiptera/microbiology ; Insect Proteins/metabolism ; Insecticide Resistance ; Nymph/drug effects ; Nymph/genetics ; Nymph/growth & development ; Nymph/microbiology ; Symbiosis
Czasopismo naukowe
Tytuł:
Coptisine modulates the pharmacokinetics of florfenicol by targeting CYP1A2, CYP2C11 and CYP3A1 in the liver and P-gp in the jejunum of rats: a pilot study.
Autorzy:
Li SC; Sichuan Key Laboratory of Animal Genetics and Breeding, Sichuan Animal Science Academy, Chengdu, P.R. China.; Veterinary Natural Medicine Research and GCP Experimental Animal Centre, Lezhi, P.R. China.
Zhang M; Sichuan Key Laboratory of Animal Genetics and Breeding, Sichuan Animal Science Academy, Chengdu, P.R. China.; Veterinary Natural Medicine Research and GCP Experimental Animal Centre, Lezhi, P.R. China.
Wang B; Sichuan Key Laboratory of Animal Genetics and Breeding, Sichuan Animal Science Academy, Chengdu, P.R. China.; Veterinary Natural Medicine Research and GCP Experimental Animal Centre, Lezhi, P.R. China.
Li XT; Sichuan Key Laboratory of Animal Genetics and Breeding, Sichuan Animal Science Academy, Chengdu, P.R. China.; Veterinary Natural Medicine Research and GCP Experimental Animal Centre, Lezhi, P.R. China.
Liang G; Sichuan Key Laboratory of Animal Genetics and Breeding, Sichuan Animal Science Academy, Chengdu, P.R. China.; Veterinary Natural Medicine Research and GCP Experimental Animal Centre, Lezhi, P.R. China.
Pokaż więcej
Źródło:
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2023 Mar; Vol. 53 (3), pp. 207-214. Date of Electronic Publication: 2023 May 15.
Typ publikacji:
Journal Article
MeSH Terms:
Cytochrome P-450 CYP1A2*/metabolism
Aryl Hydrocarbon Hydroxylases*/metabolism
Rats ; Male ; Animals ; Pilot Projects ; ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; Jejunum/metabolism ; Rats, Sprague-Dawley ; Cytochrome P-450 Enzyme System/metabolism ; Liver/metabolism ; Cytochrome P-450 CYP3A/metabolism ; Cytochrome P450 Family 2/metabolism ; Steroid 16-alpha-Hydroxylase/metabolism
Czasopismo naukowe
Tytuł:
A patient advocating for transparent science in rare disease research.
Autorzy:
Yang RR; Reflection Biotechnologies Limited, Unit 601, 6/F, Core Building 1, No. 1 Science Park East Avenue, Pak Shek Kok, New Territories, Hong Kong, China. .
Pokaż więcej
Źródło:
Orphanet journal of rare diseases [Orphanet J Rare Dis] 2023 Jan 19; Vol. 18 (1), pp. 14. Date of Electronic Publication: 2023 Jan 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Rare Diseases*
Biomedical Research*/standards
Animals ; Humans ; Mice ; Cytochrome P450 Family 4/genetics ; Cytochrome P450 Family 4/metabolism ; DNA Mutational Analysis ; Mutation ; Pedigree
SCR Disease Name:
Bietti Crystalline Dystrophy
Czasopismo naukowe
Tytuł:
Postnatal Smoke Exposure Further Increases the Hepatic Nicotine Metabolism in Prenatally Smoke Exposed Male Offspring and Is Linked with Aberrant Cyp2a5 Methylation.
Autorzy:
Lkhagvadorj K; University Medical Center Groningen, Department of Pathology and Medical Biology, University of Groningen, 9713 GZ Groningen, The Netherlands.; GRIAC Research Institute, University of Groningen, 9713 AV Groningen, The Netherlands.; Department of Pulmonology and Allergology, Mongolian National University of Medical Sciences, Ulaanbaatar 14210, Mongolia.
Zeng Z; University Medical Center Groningen, Department of Pathology and Medical Biology, University of Groningen, 9713 GZ Groningen, The Netherlands.; GRIAC Research Institute, University of Groningen, 9713 AV Groningen, The Netherlands.
Meyer KF; University Medical Center Groningen, Department of Pathology and Medical Biology, University of Groningen, 9713 GZ Groningen, The Netherlands.; GRIAC Research Institute, University of Groningen, 9713 AV Groningen, The Netherlands.
Verweij LP; University Medical Center Groningen, Department of Pathology and Medical Biology, University of Groningen, 9713 GZ Groningen, The Netherlands.; GRIAC Research Institute, University of Groningen, 9713 AV Groningen, The Netherlands.
Kooistra W; University Medical Center Groningen, Department of Pathology and Medical Biology, University of Groningen, 9713 GZ Groningen, The Netherlands.; GRIAC Research Institute, University of Groningen, 9713 AV Groningen, The Netherlands.
Reinders-Luinge M; University Medical Center Groningen, Department of Pathology and Medical Biology, University of Groningen, 9713 GZ Groningen, The Netherlands.; GRIAC Research Institute, University of Groningen, 9713 AV Groningen, The Netherlands.
Dijkhuizen HW; Faculty of Science and Engineering, University of Groningen, 9713 GZ Groningen, The Netherlands.
de Graaf IAM; Department of Pharmacokinetics, Toxicology and Targeting, Groningen Research Institute of Pharmacy, University of Groningen, 9713 AV Groningen, The Netherlands.
Plösch T; University Medical Center Groningen, Department of Obstetrics and Gynecology, University of Groningen, 9713 GZ Groningen, The Netherlands.
Hylkema MN; University Medical Center Groningen, Department of Pathology and Medical Biology, University of Groningen, 9713 GZ Groningen, The Netherlands.; GRIAC Research Institute, University of Groningen, 9713 AV Groningen, The Netherlands.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 26; Vol. 22 (1). Date of Electronic Publication: 2020 Dec 26.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Methylation*
Inactivation, Metabolic*
Aryl Hydrocarbon Hydroxylases/*metabolism
Cytochrome P450 Family 2/*metabolism
Gene Expression Regulation/*drug effects
Nicotine/*metabolism
Prenatal Exposure Delayed Effects/*pathology
Smoke/*adverse effects
Animals ; Animals, Newborn ; Aryl Hydrocarbon Hydroxylases/chemistry ; Aryl Hydrocarbon Hydroxylases/genetics ; Cytochrome P450 Family 2/chemistry ; Cytochrome P450 Family 2/genetics ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Pregnancy ; Prenatal Exposure Delayed Effects/etiology ; Prenatal Exposure Delayed Effects/metabolism ; Promoter Regions, Genetic
Czasopismo naukowe
Tytuł:
Alcohol dehydrogenase 5 of Helicoverpa armigera interacts with the CYP6B6 promoter in response to 2-tridecanone.
Autorzy:
Zhao J; Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Sciences and Technology, Xinjiang University, Urumqi, Xinjiang, China.; Key Laboratory of Oasis Agricultural Pest Management and Plant Protection Resources Utilization, College of Agriculture, Shihezi University, Shihezi, Xinjiang, China.
Wei Q; Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Sciences and Technology, Xinjiang University, Urumqi, Xinjiang, China.
Gu XR; Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Sciences and Technology, Xinjiang University, Urumqi, Xinjiang, China.
Ren SW; Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Sciences and Technology, Xinjiang University, Urumqi, Xinjiang, China.
Liu XN; Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Sciences and Technology, Xinjiang University, Urumqi, Xinjiang, China.
Pokaż więcej
Źródło:
Insect science [Insect Sci] 2020 Oct; Vol. 27 (5), pp. 1053-1066. Date of Electronic Publication: 2019 Sep 12.
Typ publikacji:
Journal Article
MeSH Terms:
Aldehyde Oxidoreductases/*genetics
Cytochrome P450 Family 6/*genetics
Insect Proteins/*genetics
Ketones/*metabolism
Moths/*genetics
Aldehyde Oxidoreductases/chemistry ; Aldehyde Oxidoreductases/metabolism ; Amino Acid Sequence ; Animals ; Base Sequence ; Cytochrome P450 Family 6/chemistry ; Cytochrome P450 Family 6/metabolism ; Insect Proteins/chemistry ; Insect Proteins/metabolism ; Larva/enzymology ; Larva/growth & development ; Larva/metabolism ; Moths/enzymology ; Moths/growth & development ; Phylogeny
Czasopismo naukowe
Tytuł:
Human Orphan Cytochrome P450 2U1 Catalyzes the ω-Hydroxylation of Leukotriene B 4 .
Autorzy:
Nouri K; Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, CNRS UMR 8601, Université Paris Cité, 45 rue des Saints-Pères, 75006 Paris, France.
Pietrancosta N; Laboratoire Neuroscience Paris Seine, CNRS UMR 8246/INSERM UMCR 18, Laboratoire des Biomolécules, CNRS UMR7203, Faculté des Sciences, Sorbonne Université, 4 Place Jussieu, 75005 Paris, France.
Le Corre L; Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, CNRS UMR 8601, Université Paris Cité, 45 rue des Saints-Pères, 75006 Paris, France.
Dansette PM; Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, CNRS UMR 8601, Université Paris Cité, 45 rue des Saints-Pères, 75006 Paris, France.
Mansuy D; Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, CNRS UMR 8601, Université Paris Cité, 45 rue des Saints-Pères, 75006 Paris, France.
Boucher JL; Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, CNRS UMR 8601, Université Paris Cité, 45 rue des Saints-Pères, 75006 Paris, France.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 23; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
Leukotriene B4*/metabolism
Cytochrome P-450 Enzyme System*/genetics
Cytochrome P-450 Enzyme System*/metabolism
Humans ; Hydroxylation ; Fatty Acids ; Cytochrome P450 Family 2/genetics ; Cytochrome P450 Family 2/metabolism
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies