- Tytuł:
- Claudin-3 overexpression increases the malignant potential of colorectal cancer cells: roles of ERK1/2 and PI3K-Akt as modulators of EGFR signaling.
- Autorzy:
- Źródło:
- PloS one [PLoS One] 2013 Sep 19; Vol. 8 (9), pp. e74994. Date of Electronic Publication: 2013 Sep 19 (Print Publication: 2013).
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Gene Expression*
Claudin-3/*genetics
Colorectal Neoplasms/*genetics
Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cell Transformation, Neoplastic/drug effects ; Cell Transformation, Neoplastic/genetics ; Claudin-1/genetics ; Claudin-1/metabolism ; Claudin-3/metabolism ; Colorectal Neoplasms/metabolism ; Epidermal Growth Factor/pharmacology ; ErbB Receptors/metabolism ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Silencing ; Humans ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Protein Transport/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/drug effects ; Tumor Stem Cell Assay
Czasopismo naukowe