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    Wyświetlanie 1-6 z 6
    Tytuł:
    Neutralising antibodies block the function of Rh5/Ripr/CyRPA complex during invasion of Plasmodium falciparum into human erythrocytes.
    Autorzy:
    Healer J; Infection and Immunity, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.
    Wong W; Infection and Immunity, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.
    Thompson JK; Infection and Immunity, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.
    He W; Infection and Immunity, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.
    Birkinshaw RW; Infection and Immunity, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.
    Miura K; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
    Long CA; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
    Soroka V; ExpreS2ion Biotechnologies, Horsholm, Denmark.
    Søgaard TMM; ExpreS2ion Biotechnologies, Horsholm, Denmark.
    Jørgensen T; ExpreS2ion Biotechnologies, Horsholm, Denmark.
    de Jongh WA; ExpreS2ion Biotechnologies, Horsholm, Denmark.
    Weir C; Infection and Immunity, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.; Schools of Chemistry and Biological Sciences, University of Edinburgh, Edinburgh, Scotland, UK.
    Svahn E; Schools of Chemistry and Biological Sciences, University of Edinburgh, Edinburgh, Scotland, UK.
    Czabotar PE; Infection and Immunity, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.
    Tham WH; Infection and Immunity, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.
    Mueller I; Infection and Immunity, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.
    Barlow PN; Schools of Chemistry and Biological Sciences, University of Edinburgh, Edinburgh, Scotland, UK.
    Cowman AF; Infection and Immunity, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.
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    Źródło:
    Cellular microbiology [Cell Microbiol] 2019 Jul; Vol. 21 (7), pp. e13030. Date of Electronic Publication: 2019 Apr 24.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Antibodies, Neutralizing/*pharmacology
    Antigens, Protozoan/*genetics
    Carrier Proteins/*genetics
    Malaria, Falciparum/*drug therapy
    Protozoan Proteins/*genetics
    Antibodies, Neutralizing/immunology ; Carrier Proteins/antagonists & inhibitors ; Erythrocytes/drug effects ; Erythrocytes/immunology ; Humans ; Malaria Vaccines/immunology ; Malaria Vaccines/pharmacology ; Malaria, Falciparum/immunology ; Malaria, Falciparum/parasitology ; Merozoites/drug effects ; Merozoites/immunology ; Plasmodium falciparum/immunology ; Plasmodium falciparum/pathogenicity ; Protozoan Proteins/antagonists & inhibitors ; Protozoan Proteins/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Production of full-length soluble Plasmodium falciparum RH5 protein vaccine using a Drosophila melanogaster Schneider 2 stable cell line system.
    Autorzy:
    Hjerrild KA; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.
    Jin J; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.
    Wright KE; Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.
    Brown RE; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.
    Marshall JM; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.
    Labbé GM; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.
    Silk SE; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.
    Cherry CJ; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.
    Clemmensen SB; ExpreS2ion Biotechnologies, SCION-DTU Science Park, Agern Allé 1, Hørsholm DK-2970, Denmark.
    Jørgensen T; ExpreS2ion Biotechnologies, SCION-DTU Science Park, Agern Allé 1, Hørsholm DK-2970, Denmark.
    Illingworth JJ; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.
    Alanine DG; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.
    Milne KH; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.
    Ashfield R; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.
    de Jongh WA; ExpreS2ion Biotechnologies, SCION-DTU Science Park, Agern Allé 1, Hørsholm DK-2970, Denmark.
    Douglas AD; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.
    Higgins MK; Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.
    Draper SJ; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.
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    Źródło:
    Scientific reports [Sci Rep] 2016 Jul 26; Vol. 6, pp. 30357. Date of Electronic Publication: 2016 Jul 26.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Carrier Proteins/*immunology
    Malaria Vaccines/*immunology
    Plasmodium falciparum/*immunology
    Animals ; Antibodies, Monoclonal/immunology ; Basigin/immunology ; Carrier Proteins/genetics ; Carrier Proteins/metabolism ; Cell Line ; Drosophila melanogaster ; Immunoglobulin G/immunology ; Malaria Vaccines/genetics ; Mutation
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Bacterial superglue enables easy development of efficient virus-like particle based vaccines.
    Autorzy:
    Thrane S; Centre for Medical Parasitology at the Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.; Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark.
    Janitzek CM; Centre for Medical Parasitology at the Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.; Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark.
    Matondo S; Kilimanjaro Clinical Research Institute, KCMC, Moshi, Tanzania.
    Resende M; Centre for Medical Parasitology at the Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.; Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark.
    Gustavsson T; Centre for Medical Parasitology at the Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.; Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark.
    de Jongh WA; ExpreS2ion Biotechnologies, SCION-DTU Science Park, Hørsholm, Denmark.
    Clemmensen S; Centre for Medical Parasitology at the Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.; Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark.; ExpreS2ion Biotechnologies, SCION-DTU Science Park, Hørsholm, Denmark.
    Roeffen W; Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.
    van de Vegte-Bolmer M; Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.
    van Gemert GJ; Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.
    Sauerwein R; Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.
    Schiller JT; Laboratory of Cellular Oncology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
    Nielsen MA; Centre for Medical Parasitology at the Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.; Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark.
    Theander TG; Centre for Medical Parasitology at the Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.; Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark.
    Salanti A; Centre for Medical Parasitology at the Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark. .; Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark. .
    Sander AF; Centre for Medical Parasitology at the Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark. .; Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark. .
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    Źródło:
    Journal of nanobiotechnology [J Nanobiotechnology] 2016 Apr 27; Vol. 14, pp. 30. Date of Electronic Publication: 2016 Apr 27.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Vaccines, Virus-Like Particle/*immunology
    Acinetobacter/immunology ; Animals ; Antigens, Bacterial/immunology ; B-Lymphocytes/immunology ; Bacteriophages/immunology ; Capsid Proteins/immunology ; Female ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Vaccination/methods
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine.
    Autorzy:
    Nielsen MA; Centre for Medical Parasitology at Department of Immunology and Microbiology, Faculty of Health and Medical Science, University of Copenhagen, and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
    Resende M; Centre for Medical Parasitology at Department of Immunology and Microbiology, Faculty of Health and Medical Science, University of Copenhagen, and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
    de Jongh WA; ExpreS2ion Biotechnologies, SCION-DTU Science Park, Hørsholm, Denmark.
    Ditlev SB; Centre for Medical Parasitology at Department of Immunology and Microbiology, Faculty of Health and Medical Science, University of Copenhagen, and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
    Mordmüller B; Eberhard Karls Universität Tübingen, Institut für Tropenmedizin, Tübingen, Germany, and Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
    Houard S; European Vaccine Initiative, Universitäts Klinikum Heidelberg, Heidelberg, Germany.
    Ndam NT; Institut de Recherche pour le Développement, UMR216 Mère et enfant face aux infections tropicales, Paris, France; PRES Sorbonne Paris Cité, Université Paris Descartes, Paris, France.
    Agerbæk MØ; Centre for Medical Parasitology at Department of Immunology and Microbiology, Faculty of Health and Medical Science, University of Copenhagen, and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
    Hamborg M; Centre for Medical Parasitology at Department of Immunology and Microbiology, Faculty of Health and Medical Science, University of Copenhagen, and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
    Massougbodji A; Faculté des Sciences de la Santé de l'Université d'Abomey-Calavi, Centre d'étude et de recherche sur le paludisme associé à la grossesse et à l'enfance, Cotonou, Bénin.
    Issifou S; Faculté des Sciences de la Santé de l'Université d'Abomey-Calavi, Centre d'étude et de recherche sur le paludisme associé à la grossesse et à l'enfance, Cotonou, Bénin.
    Strøbæk A; ExpreS2ion Biotechnologies, SCION-DTU Science Park, Hørsholm, Denmark.
    Poulsen L; ExpreS2ion Biotechnologies, SCION-DTU Science Park, Hørsholm, Denmark.
    Leroy O; European Vaccine Initiative, Universitäts Klinikum Heidelberg, Heidelberg, Germany.
    Kremsner PG; Eberhard Karls Universität Tübingen, Institut für Tropenmedizin, Tübingen, Germany, and Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
    Chippaux JP; Institut de Recherche pour le Développement, UMR216 Mère et enfant face aux infections tropicales, Paris, France; PRES Sorbonne Paris Cité, Université Paris Descartes, Paris, France; Faculté des Sciences de la Santé de l'Université d'Abomey-Calavi, Centre d'étude et de recherche sur le paludisme associé à la grossesse et à l'enfance, Cotonou, Bénin.
    Luty AJ; Institut de Recherche pour le Développement, UMR216 Mère et enfant face aux infections tropicales, Paris, France; PRES Sorbonne Paris Cité, Université Paris Descartes, Paris, France; Faculté des Sciences de la Santé de l'Université d'Abomey-Calavi, Centre d'étude et de recherche sur le paludisme associé à la grossesse et à l'enfance, Cotonou, Bénin.
    Deloron P; Institut de Recherche pour le Développement, UMR216 Mère et enfant face aux infections tropicales, Paris, France; PRES Sorbonne Paris Cité, Université Paris Descartes, Paris, France.
    Theander TG; Centre for Medical Parasitology at Department of Immunology and Microbiology, Faculty of Health and Medical Science, University of Copenhagen, and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
    Dyring C; ExpreS2ion Biotechnologies, SCION-DTU Science Park, Hørsholm, Denmark.
    Salanti A; Centre for Medical Parasitology at Department of Immunology and Microbiology, Faculty of Health and Medical Science, University of Copenhagen, and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
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    Źródło:
    PloS one [PLoS One] 2015 Sep 01; Vol. 10 (9), pp. e0135406. Date of Electronic Publication: 2015 Sep 01 (Print Publication: 2015).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antibody Formation/*immunology
    Antigens, Protozoan/*immunology
    Malaria Vaccines/*immunology
    Malaria, Falciparum/*prevention & control
    Placenta/*parasitology
    Animals ; Cross Reactions/immunology ; Drosophila melanogaster/metabolism ; Female ; Humans ; Malaria, Falciparum/immunology ; Placenta/immunology ; Plasmodium falciparum/immunology ; Pregnancy ; Protein Engineering/methods ; Recombinant Proteins
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies.
    Autorzy:
    Wright KE; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
    Hjerrild KA; Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK.
    Bartlett J; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
    Douglas AD; Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK.
    Jin J; Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK.
    Brown RE; Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK.
    Illingworth JJ; Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK.
    Ashfield R; Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK.
    Clemmensen SB; ExpreS2ion Biotechnologies, SCION-DTU Science Park, Agern Allé 1, DK-2970 Horsholm, Denmark.
    de Jongh WA; ExpreS2ion Biotechnologies, SCION-DTU Science Park, Agern Allé 1, DK-2970 Horsholm, Denmark.
    Draper SJ; Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK.
    Higgins MK; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
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    Źródło:
    Nature [Nature] 2014 Nov 20; Vol. 515 (7527), pp. 427-30. Date of Electronic Publication: 2014 Aug 17.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Malaria*/parasitology
    Antibodies, Blocking/*chemistry
    Basigin/*chemistry
    Erythrocytes/*chemistry
    Plasmodium falciparum/*chemistry
    Antibodies, Blocking/immunology ; Antigens, Protozoan/chemistry ; Antigens, Protozoan/immunology ; Basigin/immunology ; Binding Sites ; Crystallography, X-Ray ; Epitopes/chemistry ; Epitopes/immunology ; Host-Parasite Interactions/immunology ; Humans ; Models, Molecular ; Plasmodium falciparum/immunology ; Protozoan Proteins/chemistry ; Protozoan Proteins/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Physiological characterisation of acuB deletion in Aspergillus niger.
    Autorzy:
    Meijer S; Center for Microbial Biotechnology, DTU-BioSys, Lyngby, Denmark.
    de Jongh WA
    Olsson L
    Nielsen J
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    Źródło:
    Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2009 Aug; Vol. 84 (1), pp. 157-67. Date of Electronic Publication: 2009 May 15.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Gene Deletion*
    Aspergillus nidulans/*physiology
    Fungal Proteins/*genetics
    Acetates/metabolism ; Aspergillus nidulans/genetics ; Aspergillus nidulans/growth & development ; Fungal Proteins/metabolism ; Glucose/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-6 z 6

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