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Tytuł :
α-amyrin-loaded nanocapsules produce selective cytotoxic activity in leukemic cells.
Autorzy :
Neto SF; Laboratory of Innovation and Development in Pharmaceutical Technology (LIDETEF), Faculty of Pharmaceutical Sciences, Universidade Federal do Amazonas, Av. Rodrigo Octavio Ramos, 6200, Coroado, Manaus, AM CEP 69077-000, Brazil.
Prada AL; Laboratory of Innovation and Development in Pharmaceutical Technology (LIDETEF), Faculty of Pharmaceutical Sciences, Universidade Federal do Amazonas, Av. Rodrigo Octavio Ramos, 6200, Coroado, Manaus, AM CEP 69077-000, Brazil.
Achod LDR; Laboratory of Innovation and Development in Pharmaceutical Technology (LIDETEF), Faculty of Pharmaceutical Sciences, Universidade Federal do Amazonas, Av. Rodrigo Octavio Ramos, 6200, Coroado, Manaus, AM CEP 69077-000, Brazil.
Torquato HFV; Biochemistry Department, Universidade Federal de São Paulo, Rua Três de Maio 100, São Paulo, SP, CEP 04044-020, Brazil.
Lima CS; Biochemistry Department, Universidade Federal de São Paulo, Rua Três de Maio 100, São Paulo, SP, CEP 04044-020, Brazil.
Paredes-Gamero EJ; Biochemistry Department, Universidade Federal de São Paulo, Rua Três de Maio 100, São Paulo, SP, CEP 04044-020, Brazil; Pharmaceutical Sciences Post-Graduation Program, Faculty of Pharmacy, Food and Nutrition, Universidade Federal do Mato Grosso do Sul, Av. Costa e Silva, Pioneiros, Campo Grande, MS CEP 79070-900, Brazil.
Silva de Moraes MO; Thematic Microscopy and Nanotechnology Laboratory (LTMN), Instituto Nacional de Pesquisas da Amazônia (INPA), Av. Bem Te ví, 8-406. Petrópolis, Manaus, AM 69067-001, Brazil.
Lima ES; Laboratory of Innovation and Development in Pharmaceutical Technology (LIDETEF), Faculty of Pharmaceutical Sciences, Universidade Federal do Amazonas, Av. Rodrigo Octavio Ramos, 6200, Coroado, Manaus, AM CEP 69077-000, Brazil.
Sosa EH; Department of Biochemistry & Molecular Biology, Dalhousie University, Sir Charles Tupper Medical Building, 5850 College Street, Halifax, Nova Scotia B3H 4R2, Canada.
de Souza TP; Laboratory of Innovation and Development in Pharmaceutical Technology (LIDETEF), Faculty of Pharmaceutical Sciences, Universidade Federal do Amazonas, Av. Rodrigo Octavio Ramos, 6200, Coroado, Manaus, AM CEP 69077-000, Brazil.
Amado JRR; Laboratory of Pharmaceutical Technology (LTF), Faculty of Pharmacy, Food and Nutrition, Universidade Federal do Mato Grosso do Sul, Av. Costa e Silva, Pioneiros, Campo Grande, MS CEP 79070-900, Brazil. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Jul; Vol. 139, pp. 111656. Date of Electronic Publication: 2021 May 08.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Effect of Topical Instillation of Pegaptanib Sodium Upon Inflammatory Corneal Neovascularization in Rabbits.
Autorzy :
Andrade N; Research and Development Center for Medicines, Federal University of Ceara, Fortaleza, Ceará, Brazil.
Crispim Ribeiro J; Department of Ophthalmology, Christus University Center (Unichristus), Fortaleza, Ceará, Brazil.
Araújo E Silva PM; Department of Ophthalmology, Christus University Center (Unichristus), Fortaleza, Ceará, Brazil.
Savio D; Department of Ophthalmology, Christus University Center (Unichristus), Fortaleza, Ceará, Brazil.
Fechine FV; Research and Development Center for Medicines, Federal University of Ceara, Fortaleza, Ceará, Brazil.
de Moraes MO; Research and Development Center for Medicines, Federal University of Ceara, Fortaleza, Ceará, Brazil.
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Źródło :
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics [J Ocul Pharmacol Ther] 2021 Jun; Vol. 37 (5), pp. 277-283. Date of Electronic Publication: 2021 Apr 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Diazepam's antifungal activity in fluconazole-resistant Candida spp. and biofilm inhibition in C. albicans : evaluation of the relationship with the proteins ALS3 and SAP5.
Autorzy :
Juvêncio da Silva L; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
Dias Barroso FD; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
Vieira LS; Christus University Center (UNICHRISTUS), Fortaleza, CE, Brazil.
Carlos Mota DR; Christus University Center (UNICHRISTUS), Fortaleza, CE, Brazil.
da Silva Firmino BK; Christus University Center (UNICHRISTUS), Fortaleza, CE, Brazil.
Rocha da Silva C; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
de Farias Cabral VP; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
Cândido TM; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
Sá LGDAV; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
Barbosa da Silva WM; Christus University Center (UNICHRISTUS), Fortaleza, CE, Brazil.
Silva J; Department of Chemistry, Group for Theoretical Chemistry and Electrochemistry (GQTE), State University of Ceará, Limoeiro do Norte, Ceará, Brazil.
Marinho ES; Department of Chemistry, Group for Theoretical Chemistry and Electrochemistry (GQTE), State University of Ceará, Limoeiro do Norte, Ceará, Brazil.
Cavalcanti BC; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil.; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.
de Moraes MO; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil.; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.
Júnior HVN; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
de Andrade Neto JB; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.; Christus University Center (UNICHRISTUS), Fortaleza, CE, Brazil.
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Źródło :
Journal of medical microbiology [J Med Microbiol] 2021 Mar; Vol. 70 (3). Date of Electronic Publication: 2021 Feb 09.
Typ publikacji :
Journal Article
MeSH Terms :
Antifungal Agents/*pharmacology
Biofilms/*drug effects
Candida/*drug effects
Diazepam/*pharmacology
Drug Resistance, Fungal/*drug effects
Aspartic Acid Endopeptidases/metabolism ; Candida/pathogenicity ; Fluconazole/pharmacology ; Fungal Proteins/metabolism
Czasopismo naukowe
Tytuł :
Diterpenoids from Leaves of Cultivated Plectranthus ornatus.
Autorzy :
Mesquita LSF; Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará, Fortaleza-CE, Brazil.
Matos TS; Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará, Fortaleza-CE, Brazil.
Ávila FDN; Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará, Fortaleza-CE, Brazil.
Batista ADS; Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará, Fortaleza-CE, Brazil.
Moura AF; Núcleo de Pesquisa e Desenvolvimento de Medicamentos, Universidade Federal do Ceará, Fortaleza-CE, Brazil.
de Moraes MO; Núcleo de Pesquisa e Desenvolvimento de Medicamentos, Universidade Federal do Ceará, Fortaleza-CE, Brazil.
da Silva MCM; Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Fortaleza-CE, Brazil.
Ferreira TLA; Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Fortaleza-CE, Brazil.
Nascimento NRF; Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Fortaleza-CE, Brazil.
Monteiro NKV; Departamento de Química Analítica e Físico-Química, Universidade Federal do Ceará, Fortaleza-CE, Brazil.
Pessoa ODL; Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará, Fortaleza-CE, Brazil.
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Źródło :
Planta medica [Planta Med] 2021 Feb; Vol. 87 (1-02), pp. 124-135. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article
MeSH Terms :
Plectranthus*
Animals ; Diterpenes/pharmacology ; Guinea Pigs ; Humans ; Molecular Structure ; Plant Extracts/pharmacology ; Plant Leaves
Czasopismo naukowe
Tytuł :
Association of MICA and HLA-B alleles with leprosy in two endemic populations in Brazil.
Autorzy :
Jarduli LR; Department of Clinical Analysis and Biomedicine, Graduate Program in Biosciences and Physiopathology, State University of Maringá, Maringá, Brazil.
Alves HV; Department of Clinical Analysis and Biomedicine, Graduate Program in Biosciences and Physiopathology, State University of Maringá, Maringá, Brazil.
de Souza VH; Department of Clinical Analysis and Biomedicine, Graduate Program in Biosciences and Physiopathology, State University of Maringá, Maringá, Brazil.
Uaska Sartori PV; Graduate Program in Health Sciences, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, Brazil.
Fava VM; Infectious Diseases and Immunity in Global Health (IDIGH) Program at the Research Institute of the McGill University Health Centre (RI-MUHC), Montreal, QC, Canada.
de Souza FC; Lauro de Souza Lima Institute, Bauru, Brazil.
Marcos EVC; Lauro de Souza Lima Institute, Bauru, Brazil.
Pereira AC; Lauro de Souza Lima Institute, Bauru, Brazil.
Dias-Baptista IMF; Lauro de Souza Lima Institute, Bauru, Brazil.
Virmond MDCL; Lauro de Souza Lima Institute, Bauru, Brazil.
de Moraes MO; Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Brazil.
Mira MT; Graduate Program in Health Sciences, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, Brazil.
Visentainer JEL; Graduate Program in Health Sciences, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, Brazil.; Department of Basic Health Sciences, State University of Maringá, Maringá, Brazil.
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Źródło :
International journal of immunogenetics [Int J Immunogenet] 2021 Feb; Vol. 48 (1), pp. 25-35. Date of Electronic Publication: 2020 Nov 05.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
HLA-B Antigens/*genetics
Histocompatibility Antigens Class I/*genetics
Leprosy/*immunology
3' Untranslated Regions/genetics ; 5' Untranslated Regions/genetics ; Adolescent ; Adult ; Alleles ; Brazil/epidemiology ; Case-Control Studies ; Child ; Endemic Diseases ; Ethnic Groups/genetics ; Exons/genetics ; Family Health ; Female ; Gene Frequency ; Genetic Predisposition to Disease ; Genotype ; Haplotypes/genetics ; Humans ; Leprosy/epidemiology ; Leprosy/genetics ; Linkage Disequilibrium ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Protein Domains ; Young Adult
Czasopismo naukowe
Tytuł :
Development and in vitro evaluation of microparticles of fluoxetine in galactomannan against biofilms of S. aureus methicilin resistant.
Autorzy :
Josino MAA; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil. Electronic address: .
Rocha da Silva C; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.
de Andrade Neto JB; Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; Christus University Center (UNICHRISTUS), Fortaleza, CE, Brazil.
Barroso FDD; Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.
Juvêncio da Silva L; Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.
Cavalcanti BC; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.
de Moraes MO; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.
Brito DHA; Laboratory of Polymers and Materials Innovation, Department of Organic and Inorganic Chemistry, Sciences Center, Federal University of Ceará, Campus of Pici, 60455-760 Fortaleza, CE, Brazil.
Ricardo NMPS; Laboratory of Polymers and Materials Innovation, Department of Organic and Inorganic Chemistry, Sciences Center, Federal University of Ceará, Campus of Pici, 60455-760 Fortaleza, CE, Brazil.
Júnior HVN; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.
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Źródło :
Carbohydrate polymers [Carbohydr Polym] 2021 Jan 15; Vol. 252, pp. 117184. Date of Electronic Publication: 2020 Oct 05.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Repositioning*
Anti-Bacterial Agents/*pharmacology
Biofilms/*drug effects
Fluoxetine/*pharmacology
Methicillin-Resistant Staphylococcus aureus/*drug effects
Drug Carriers/chemistry ; Drug Liberation ; Mannans/chemistry ; Microbial Sensitivity Tests
Czasopismo naukowe
Tytuł :
Etomidate is devoid of genotoxicty and mutagenicity in human lymphocytes and in the Salmonella typhimurium/microsomal activation test.
Autorzy :
Cavalcanti BC; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil. Electronic address: .b.
do Amaral Valente Sá LG; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
de Andrade Neto JB; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; Christus University Center (UNICHRISTUS), Fortaleza, CE, Brazil; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
de Sousa Silva AA; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil.
Rios MEF; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.
Barreto FS; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil.
de Oliveira Ferreira JR; School of Medical Sciences, State University of Health Sciences of Alagoas (UNCISAL), AL, Brazil.
da Silva CR; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
Barroso FD; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
Magalhães HIF; Department of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa, PB, Brazil.
Nobre HV Jr; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
de Moraes MO; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil.
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Źródło :
Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2020 Oct; Vol. 68, pp. 104946. Date of Electronic Publication: 2020 Jul 15.
Typ publikacji :
Journal Article
MeSH Terms :
Etomidate/*toxicity
Hypnotics and Sedatives/*toxicity
Lymphocytes/*drug effects
Salmonella typhimurium/*drug effects
Adult ; Animals ; Cell Survival/drug effects ; Cells, Cultured ; DNA Damage ; Erythrocytes/drug effects ; Hemolysis/drug effects ; Humans ; Lymphocytes/metabolism ; Mice ; Mutagenicity Tests ; Salmonella typhimurium/genetics ; Young Adult
Czasopismo naukowe
Tytuł :
Antifungal activity of etomidate against growing biofilms of fluconazole-resistant Candida spp. strains, binding to mannoproteins and molecular docking with the ALS3 protein.
Autorzy :
Gurgel do Amaral Valente Sá L; Drug Research and Development Center, Federal University of Ceará, Fortaleza, 60430-275, CE, Brazil.; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, 60430-170, CE, Brazil.
da Silva CR; Drug Research and Development Center, Federal University of Ceará, Fortaleza, 60430-275, CE, Brazil.; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, 60430-170, CE, Brazil.
Neto JBA; Drug Research and Development Center, Federal University of Ceará, Fortaleza, 60430-275, CE, Brazil.; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, 60430-170, CE, Brazil.
do Nascimento FBSA; Drug Research and Development Center, Federal University of Ceará, Fortaleza, 60430-275, CE, Brazil.; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, 60430-170, CE, Brazil.
Barroso FDD; Drug Research and Development Center, Federal University of Ceará, Fortaleza, 60430-275, CE, Brazil.; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, 60430-170, CE, Brazil.
da Silva LJ; Drug Research and Development Center, Federal University of Ceará, Fortaleza, 60430-275, CE, Brazil.; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, 60430-170, CE, Brazil.
Cabral VPF; Drug Research and Development Center, Federal University of Ceará, Fortaleza, 60430-275, CE, Brazil.; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, 60430-170, CE, Brazil.
Barbosa AD; Drug Research and Development Center, Federal University of Ceará, Fortaleza, 60430-275, CE, Brazil.; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, 60430-170, CE, Brazil.
Silva J; Department of Chemistry, Group of Theoretical Chemistry and Electrochemistry (GQTE), State University of Ceará, Limoeiro do Norte, 62930-000, CE, Brazil.
Marinho ES; Department of Chemistry, Group of Theoretical Chemistry and Electrochemistry (GQTE), State University of Ceará, Limoeiro do Norte, 62930-000, CE, Brazil.
de Moraes MO; Department of Physiology and Pharmacology, Neuropharmacology Laboratory, Federal University of Ceará, Fortaleza, 60430-275, CE, Brazil.
Rios MEF; Drug Research and Development Center, Federal University of Ceará, Fortaleza, 60430-275, CE, Brazil.
Cavalcanti BC; Drug Research and Development Center, Federal University of Ceará, Fortaleza, 60430-275, CE, Brazil.
Lima ISP; Departament of Pharmacology, School of Medicine, Federal University of Ceará, Barbalha, 63048-080, CE, Brazil.
Júnior HVN; Drug Research and Development Center, Federal University of Ceará, Fortaleza, 60430-275, CE, Brazil.
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Źródło :
Journal of medical microbiology [J Med Microbiol] 2020 Oct; Vol. 69 (10), pp. 1221-1227. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji :
Journal Article
MeSH Terms :
Candida/*drug effects
Drug Resistance, Fungal/*drug effects
Etomidate/*pharmacology
Antifungal Agents/metabolism ; Antifungal Agents/pharmacology ; Biofilms/drug effects ; Candida albicans/drug effects ; Etomidate/metabolism ; Fluconazole/pharmacology ; Fungal Proteins/metabolism ; Humans ; Membrane Glycoproteins/metabolism ; Microbial Sensitivity Tests ; Molecular Docking Simulation/methods
Czasopismo naukowe
Tytuł :
Antifungal and antiprotozoal green amino acid-based rhamnolipids: Mode of action, antibiofilm efficiency and selective activity against resistant Candida spp. strains and Acanthamoeba castellanii.
Autorzy :
da Silva A; Department of Biology, Healthcare and the Environment, Section Microbiology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain.
Nobre H Jr; Laboratory of Bioprospection in Antimicrobial Molecules, Federal University of Ceará, Fortaleza, Brazil.
Sampaio L; Laboratory of Bioprospection in Antimicrobial Molecules, Federal University of Ceará, Fortaleza, Brazil.
Nascimento BD; Laboratory of Bioprospection in Antimicrobial Molecules, Federal University of Ceará, Fortaleza, Brazil.
da Silva C; Laboratory of Bioprospection in Antimicrobial Molecules, Federal University of Ceará, Fortaleza, Brazil.
de Andrade Neto JB; Laboratory of Bioprospection in Antimicrobial Molecules, Federal University of Ceará, Fortaleza, Brazil.
Manresa Á; Department of Biology, Healthcare and the Environment, Section Microbiology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain.
Pinazo A; Department of Surfactants and Nanobiotechnology, IQAC-CSIC, Barcelona, Spain.
Cavalcanti B; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Brazil.
de Moraes MO; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Brazil.
Ruiz-Trillo I; Institute of Evolutionary Biology (CSIC- Pompeu Fabra University), Barcelona, Spain; Department of Genetics, Microbiology and Statistics, University of Barcelona, ICREA, Barcelona, Spain.
Antó M; Institute of Evolutionary Biology (CSIC- Pompeu Fabra University), Barcelona, Spain.
Morán C; Department of Physiology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain.
Pérez L; Department of Surfactants and Nanobiotechnology, IQAC-CSIC, Barcelona, Spain. Electronic address: .
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Źródło :
Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2020 Sep; Vol. 193, pp. 111148. Date of Electronic Publication: 2020 May 26.
Typ publikacji :
Journal Article
MeSH Terms :
Acanthamoeba castellanii/*drug effects
Amino Acids/*pharmacology
Antifungal Agents/*pharmacology
Antiprotozoal Agents/*pharmacology
Candida/*drug effects
Glycolipids/*pharmacology
Amino Acids/chemistry ; Antifungal Agents/chemistry ; Antiprotozoal Agents/chemistry ; Biofilms/drug effects ; Drug Resistance, Fungal/drug effects ; Glycolipids/chemistry ; Microbial Sensitivity Tests ; Molecular Conformation ; Parasitic Sensitivity Tests
Czasopismo naukowe
Tytuł :
Antitumor Potential of the Isoflavonoids (+)- and (-)-2,3,9-Trimethoxypterocarpan: Mechanism-of-Action Studies.
Autorzy :
Farias K; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza, CE 60430-275, Brazil.
da Costa RF; Department of Natural Sciences, Mathematics and Statistics, Federal Rural University of the Semi-Arid Region - UFERSA, Mossoró - RN 59625-900, Brazil.
Meira AS; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza, CE 60430-275, Brazil.
Diniz-Filho J; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza, CE 60430-275, Brazil.
Bezerra EM; Department of Natural Sciences, Mathematics and Statistics, Federal Rural University of the Semi-Arid Region - UFERSA, Mossoró - RN 59625-900, Brazil.
Freire VN; Department of Physics, Science Center, Federal University of Ceará, Fortaleza, CE 60430-275, Brazil.
Guest P; Research School of Chemistry, Institute of Advanced Studies, The Australian National University, Canberra, ACT 2601, Australia.
Nikahd M; Research School of Chemistry, Institute of Advanced Studies, The Australian National University, Canberra, ACT 2601, Australia.
Ma X; Research School of Chemistry, Institute of Advanced Studies, The Australian National University, Canberra, ACT 2601, Australia.
Gardiner MG; Research School of Chemistry, Institute of Advanced Studies, The Australian National University, Canberra, ACT 2601, Australia.
Banwell MG; Research School of Chemistry, Institute of Advanced Studies, The Australian National University, Canberra, ACT 2601, Australia.; Institute for Advanced and Applied Chemical Synthesis, Jinan University, Guangzhou 510632, China.
de Oliveira MDCF; Department of Organic and Inorganic Chemistry, Science Center, Federal University of Ceará, Fortaleza, CE 60430-275, Brazil.
de Moraes MO; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza, CE 60430-275, Brazil.
do Ó Pessoa C; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza, CE 60430-275, Brazil.
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Źródło :
ACS medicinal chemistry letters [ACS Med Chem Lett] 2020 May 20; Vol. 11 (6), pp. 1274-1280. Date of Electronic Publication: 2020 May 20 (Print Publication: 2020).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Evaluation of Genotoxicity and Mutagenicity of Ketamine on Human Peripheral Blood Leukocytes and in Salmonella typhimurium.
Autorzy :
Cavalcanti BC; Department of Physiology and Pharmacology, Federal University of Ceara, Fortaleza, CE, Brazil; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil. Electronic address: .
de Andrade Neto JB; School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceara, Fortaleza, CE, Brazil; Christus University Center (UNICHRISTUS), Fortaleza, CE, Brazil; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil.
de Sousa Silva AA; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil.
Barreto FS; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil.
de Oliveira Ferreira JR; School of Medical Sciences, State University of Health Sciences of Alagoas (UNCISAL), AL, Brazil.
da Silva CR; School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceara, Fortaleza, CE, Brazil; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil.
Aires do Nascimento FBS; School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceara, Fortaleza, CE, Brazil; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil.
do Amaral Valente Sá LG; School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceara, Fortaleza, CE, Brazil; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil.
Magalhães HIF; Department of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa, PB, Brazil.
Nobre Júnior HV; School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceara, Fortaleza, CE, Brazil; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil.
de Moraes MO; Department of Physiology and Pharmacology, Federal University of Ceara, Fortaleza, CE, Brazil; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil.
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Źródło :
Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2020 Feb; Vol. 62, pp. 104718. Date of Electronic Publication: 2019 Nov 09.
Typ publikacji :
Journal Article
MeSH Terms :
Anesthetics, Dissociative/*toxicity
Ketamine/*toxicity
Leukocytes/*drug effects
Mutagens/*toxicity
Salmonella typhimurium/*drug effects
Salmonella typhimurium/*genetics
Apoptosis/drug effects ; Cell Survival/drug effects ; Chromosome Aberrations/chemically induced ; Comet Assay ; DNA Breaks ; DNA Damage ; Hemolysis/drug effects ; Humans ; Lipid Peroxidation/drug effects ; Mutagenicity Tests ; Oxidative Stress
Czasopismo naukowe
Tytuł :
Impact of Bariatric Surgery on the Pharmacokinetics Parameters of Amoxicillin.
Autorzy :
Rocha MBS; Clinical Pharmacology Unit, Drug Research and Development Center, Federal University of Ceara (UFC), Rua Cel. Nunes de Melo 1000 - Rodolfo Teófilo, Fortaleza, Ceará, 60430-275, Brazil. .
De Nucci G; Faculty of Medical Sciences, Department of Pharmacology, State University of Campinas, Campinas, São Paulo, Brazil.
Lemos FN; Unit of Bariatric Surgery, Hospital General Dr. César Cals, Avenida Imperador, 545, centro, Fortaleza, 60015-152, CE, Brazil.
de Albuquerque Lima Babadopulos RF; Unit of Bariatric Surgery, Hospital General Dr. César Cals, Avenida Imperador, 545, centro, Fortaleza, 60015-152, CE, Brazil.
Rohleder AVP; Clinical Pharmacology Unit, Drug Research and Development Center, Federal University of Ceara (UFC), Rua Cel. Nunes de Melo 1000 - Rodolfo Teófilo, Fortaleza, Ceará, 60430-275, Brazil.
Fechine FV; Clinical Pharmacology Unit, Drug Research and Development Center, Federal University of Ceara (UFC), Rua Cel. Nunes de Melo 1000 - Rodolfo Teófilo, Fortaleza, Ceará, 60430-275, Brazil.
Antunes NJ; Faculty of Medical Sciences, Department of Pharmacology, State University of Campinas, Campinas, São Paulo, Brazil.
Mendes GD; Department of Pharmacology, Metropolitan University of Santos, Santos, Brazil.; Department of Pharmacology, Faculty Medicine, São Leopoldo Mandic, Campinas, Brazil.
do Nascimento DF; Clinical Pharmacology Unit, Drug Research and Development Center, Federal University of Ceara (UFC), Rua Cel. Nunes de Melo 1000 - Rodolfo Teófilo, Fortaleza, Ceará, 60430-275, Brazil.
de Moraes MO; Clinical Pharmacology Unit, Drug Research and Development Center, Federal University of Ceara (UFC), Rua Cel. Nunes de Melo 1000 - Rodolfo Teófilo, Fortaleza, Ceará, 60430-275, Brazil.
de Moraes MEA; Clinical Pharmacology Unit, Drug Research and Development Center, Federal University of Ceara (UFC), Rua Cel. Nunes de Melo 1000 - Rodolfo Teófilo, Fortaleza, Ceará, 60430-275, Brazil.
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Źródło :
Obesity surgery [Obes Surg] 2019 Mar; Vol. 29 (3), pp. 917-927.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Gastric Bypass*
Amoxicillin/*pharmacokinetics
Anti-Bacterial Agents/*pharmacokinetics
Obesity, Morbid/*metabolism
Obesity, Morbid/*surgery
Weight Loss/*physiology
Administration, Oral ; Adult ; Amoxicillin/administration & dosage ; Amoxicillin/blood ; Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/blood ; Body Mass Index ; Chromatography, Liquid ; Female ; Humans ; Male ; Middle Aged ; Obesity, Morbid/blood ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Study of tensiometric properties, microbiological and collagen content in nile tilapia skin submitted to different sterilization methods.
Autorzy :
Alves APNN; Nursing, Dentistry and Pharmacy School of the Federal University of Ceara, 07, 17th Street, Maracanaú, Fortaleza, Ceará, 61925-430, Brazil.; Pharmaceutical Biochemistry of the Nuclear and Energy Research Institute of University of São Paulo (IPEN), São Paulo, Brazil.
Lima Júnior EM; Institute of Burning Support, Fortaleza, Ceará, Brazil.
Piccolo NS; First Aid Station for Burning of Goiânia, Goiânia, Goiás, Brazil.
de Miranda MJB; Hospital São Marcos/Rede Dor, Recife, Pernambuco, Brazil.
Lima Verde MEQ; Nursing, Dentistry and Pharmacy School of the Federal University of Ceara, 07, 17th Street, Maracanaú, Fortaleza, Ceará, 61925-430, Brazil.
Ferreira Júnior AEC; Nursing, Dentistry and Pharmacy School of the Federal University of Ceara, 07, 17th Street, Maracanaú, Fortaleza, Ceará, 61925-430, Brazil. .
de Barros Silva PG; Nursing, Dentistry and Pharmacy School of the Federal University of Ceara, 07, 17th Street, Maracanaú, Fortaleza, Ceará, 61925-430, Brazil.
Feitosa VP; Nursing, Dentistry and Pharmacy School of the Federal University of Ceara, 07, 17th Street, Maracanaú, Fortaleza, Ceará, 61925-430, Brazil.
de Bandeira TJPG; Microbiologist of Postgraduate Program in Medical Microbiology - Federal University of Ceara, Fortaleza, Ceará, Brazil.
Mathor MB; Pharmaceutical Biochemistry of the Nuclear and Energy Research Institute of University of São Paulo (IPEN), São Paulo, Brazil.
de Moraes MO; Drug Research and Development Center- NPDM/Fortaleza, Ceará, Brazil.
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Źródło :
Cell and tissue banking [Cell Tissue Bank] 2018 Sep; Vol. 19 (3), pp. 373-382. Date of Electronic Publication: 2018 Jan 29.
Typ publikacji :
Journal Article
MeSH Terms :
Cichlids/*microbiology
Collagen/*analysis
Skin/*microbiology
Skin/*ultrastructure
Sterilization/*methods
Animals ; Burns/therapy ; Gamma Rays ; Skin/drug effects ; Skin/radiation effects ; Tissue Engineering
Czasopismo naukowe
Tytuł :
Action mechanism of naphthofuranquinones against fluconazole-resistant Candida tropicalis strains evidenced by proteomic analysis: The role of increased endogenous ROS.
Autorzy :
de Andrade Neto JB; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection and Experiments in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Department of Pathology and Legal Medicine, School of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil.
da Silva CR; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection and Experiments in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Christus University Center (UNICHRISTUS), Fortaleza, CE, Brazil.
Campos RS; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection and Experiments in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Christus University Center (UNICHRISTUS), Fortaleza, CE, Brazil.
do Nascimento FBSA; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection and Experiments in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Department of Pathology and Legal Medicine, School of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil.
Sampaio LS; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection and Experiments in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Department of Pathology and Legal Medicine, School of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil.
da Silva AR; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection and Experiments in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
Josino MAA; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection and Experiments in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Department of Pathology and Legal Medicine, School of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil.
de Moraes MO; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil.
Lobo MDP; School of Pharmacy, University of Fortaleza, Fortaleza, CE, Brazil.
Moreno FBMB; School of Pharmacy, University of Fortaleza, Fortaleza, CE, Brazil.
Moreira ACOM; School of Pharmacy, University of Fortaleza, Fortaleza, CE, Brazil.
de Azevedo Moreira R; School of Pharmacy, University of Fortaleza, Fortaleza, CE, Brazil.
Grangeiro TB; Department of Biology, Science Center, Molecular Genetics Laboratory, Federal University of Ceará, CE, Brazil.
da Silva Júnior EN; Institute of Exact Sciences, Department of Chemistry, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.
Magalhães HIF; Department of Pharmaceutical Sciences, Federal University of Paraiba, University City, João Pessoa, PB, Brazil.
Rocha DD; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil.
Cavalcanti BC; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil.
Júnior HVN; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection and Experiments in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Department of Pathology and Legal Medicine, School of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil. Electronic address: .
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Źródło :
Microbial pathogenesis [Microb Pathog] 2018 Apr; Vol. 117, pp. 32-42. Date of Electronic Publication: 2017 Dec 08.
Typ publikacji :
Journal Article
MeSH Terms :
Proteomics*
Antifungal Agents/*pharmacology
Candida tropicalis/*drug effects
Candida tropicalis/*metabolism
Drug Resistance, Fungal/*drug effects
Drug Resistance, Fungal/*physiology
Naphthoquinones/*pharmacology
Reactive Oxygen Species/*metabolism
Antifungal Agents/chemical synthesis ; Antifungal Agents/chemistry ; Candida tropicalis/genetics ; Candidemia/microbiology ; Cell Cycle/drug effects ; DNA Damage/drug effects ; DNA, Fungal/genetics ; Energy Metabolism/drug effects ; Fluconazole/pharmacology ; Glycolysis/drug effects ; Membrane Potential, Mitochondrial/drug effects ; Microbial Sensitivity Tests ; Mitochondria/drug effects ; Naphthoquinones/chemical synthesis ; Naphthoquinones/chemistry ; Stress, Psychological
Czasopismo naukowe
Tytuł :
Tryptophan catabolites along the indoleamine 2,3-dioxygenase pathway as a biological link between depression and cancer.
Autorzy :
Barreto FS; Laboratory of Experimental Oncology.
Chaves Filho AJM; Neuropsychopharmacology Laboratory.
de Araújo MCCR; Clinical Pharmacology Unit, Drug Research and Development Center, Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
de Moraes MO; Laboratory of Experimental Oncology.
de Moraes MEA; Clinical Pharmacology Unit, Drug Research and Development Center, Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Maes M; Impact Strategic Research Center, Department of Psychiatry, Deakin University, Geelong, Victoria, Australia.; Department of Psychiatry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
de Lucena DF; Neuropsychopharmacology Laboratory.
Macedo DS; Neuropsychopharmacology Laboratory.
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Źródło :
Behavioural pharmacology [Behav Pharmacol] 2018 Apr; Vol. 29 (2 and 3-Spec Issue), pp. 165-180.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Indoleamine-Pyrrole 2,3,-Dioxygenase/*physiology
Tryptophan/*metabolism
Tryptophan/*physiology
Animals ; Depression/immunology ; Depression/metabolism ; Depression/physiopathology ; Depressive Disorder/physiopathology ; Humans ; Immunity/physiology ; Indoleamine-Pyrrole 2,3,-Dioxygenase/drug effects ; Indoles ; Inflammation ; Neoplasms/immunology ; Neoplasms/physiopathology ; Oxidative Stress ; Serotonin ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Annonalide and derivatives: Semisynthesis, cytotoxic activities and studies on interaction of annonalide with DNA.
Autorzy :
Marques RA; Department of Organic and Inorganic Chemistry, Federal University of Ceará, Fortaleza, Ceará, Brazil; Northern Educational Union - UNINORTE, Rio Branco, Acre, Brazil.
Gomes AOCV; Department of Organic and Inorganic Chemistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.
de Brito MV; Department of Organic and Inorganic Chemistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Dos Santos ALP; Department of Organic and Inorganic Chemistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.
da Silva GS; Department of Organic and Inorganic Chemistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.
de Lima LB; Department of Organic and Inorganic Chemistry, Federal University of Ceará, Fortaleza, Ceará, Brazil; Catholic Center of Quixadá - Unicatólica, Quixadá, Ceará, Brazil.
Nunes FM; Department of Organic and Inorganic Chemistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.
de Mattos MC; Department of Organic and Inorganic Chemistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.
de Oliveira FCE; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Ceará, Brazil.
do Ó Pessoa C; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Ceará, Brazil.
de Moraes MO; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Ceará, Brazil.
de Fátima Â; Department of Chemistry, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Franco LL; Department of Chemistry, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Silva MM; Institute of Chemistry and Biotechnology, Federal University of Alagoas, Maceió, Alagoas, Brazil.
Dantas MDA; Institute of Chemistry and Biotechnology, Federal University of Alagoas, Maceió, Alagoas, Brazil.
Santos JCC; Institute of Chemistry and Biotechnology, Federal University of Alagoas, Maceió, Alagoas, Brazil.
Figueiredo IM; Institute of Chemistry and Biotechnology, Federal University of Alagoas, Maceió, Alagoas, Brazil.
da Silva-Júnior EF; Institute of Chemistry and Biotechnology, Federal University of Alagoas, Maceió, Alagoas, Brazil.
de Aquino TM; Institute of Chemistry and Biotechnology, Federal University of Alagoas, Maceió, Alagoas, Brazil.
de Araújo-Júnior JX; Institute of Chemistry and Biotechnology, Federal University of Alagoas, Maceió, Alagoas, Brazil; Nursing and Pharmacy School, Federal University of Alagoas, Maceió, Alagoas, Brazil.
de Oliveira MCF; Department of Organic and Inorganic Chemistry, Federal University of Ceará, Fortaleza, Ceará, Brazil. Electronic address: .
Leslie Gunatilaka AA; Natural Products Center, University of Arizona, Tucson, AZ, United States.
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Źródło :
Journal of photochemistry and photobiology. B, Biology [J Photochem Photobiol B] 2018 Feb; Vol. 179, pp. 156-166. Date of Electronic Publication: 2018 Feb 03.
Typ publikacji :
Journal Article
MeSH Terms :
Cyclooctanes/*chemistry
DNA/*chemistry
Ketones/*chemistry
Animals ; Binding Sites ; Cattle ; Cell Line, Tumor ; Cell Survival ; Cyclooctanes/chemical synthesis ; Cyclooctanes/toxicity ; DNA/metabolism ; Drug Screening Assays, Antitumor ; Humans ; Ketones/chemical synthesis ; Ketones/toxicity ; Molecular Docking Simulation ; Nucleic Acid Conformation ; Spectrophotometry ; Static Electricity ; Thermodynamics ; Transition Temperature
Czasopismo naukowe
Tytuł :
Impact of testicular sperm extraction and testicular sperm aspiration on gonadal function in an experimental rat model.
Autorzy :
Barroso LVS; Divisão de Urologia, Universidade Federal do Ceará, CE, Brasil.
Reges R; Divisão de Urologia, Universidade Federal do Ceará, CE, Brasil.
Cerqueira JBG; Divisão de Urologia, Universidade Federal do Ceará, CE, Brasil.
Miranda EP; Divisão de Urologia, Universidade Federal do Ceará, CE, Brasil.
de Alcantara RJA; Divisão de Urologia, Universidade Federal do Ceará, CE, Brasil.
Jamacaru FVF; Departamento de Farmacologia, Universidade Federal do Ceará, CE, Brasil.
de Moraes MO; Departamento de Farmacologia, Universidade Federal do Ceará, CE, Brasil.
Medeiros MADS; Departamento de Farmacologia, Universidade Federal do Ceará, CE, Brasil.
Gonzaga-Silva LF; Divisão de Urologia, Universidade Federal do Ceará, CE, Brasil.
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Źródło :
International braz j urol : official journal of the Brazilian Society of Urology [Int Braz J Urol] 2018 Jan-Feb; Vol. 44 (1), pp. 172-179.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Sperm Retrieval*/adverse effects
Sperm Motility/*physiology
Spermatogenesis/*physiology
Spermatozoa/*physiology
Testis/*physiology
Animals ; Male ; Models, Animal ; Orchiopexy/methods ; Pilot Projects ; Random Allocation ; Rats ; Rats, Wistar ; Testis/surgery ; Testosterone/biosynthesis
Czasopismo naukowe
Tytuł :
Alkaloid and acetogenin-rich fraction from Annona crassiflora fruit peel inhibits proliferation and migration of human liver cancer HepG2 cells.
Autorzy :
Justino, Allisson B. (AUTHOR)
Florentino, Rodrigo M. (AUTHOR)
França, Andressa (AUTHOR)
Filho, Antonio C. M. L. (AUTHOR)
Franco, Rodrigo R. (AUTHOR)
Saraiva, André L. (AUTHOR)
Fonseca, Matheus C. (AUTHOR)
Leite, Maria F. (AUTHOR)
Salmen Espindola, Foued (AUTHOR)
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Źródło :
PLoS ONE. 7/8/2021, Vol. 16 Issue 7, p1-21. 21p.
Czasopismo naukowe
Tytuł :
In vitro anti-Candida activity of selective serotonin reuptake inhibitors against fluconazole-resistant strains and their activity against biofilm-forming isolates.
Autorzy :
Costa Silva RA; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Department of Pathology and Legal Medicine, School of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil.
da Silva CR; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Christus University Center (UNICHRISTUS), Fortaleza, CE, Brazil.
de Andrade Neto JB; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Department of Pathology and Legal Medicine, School of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil.
da Silva AR; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
Campos RS; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Christus University Center (UNICHRISTUS), Fortaleza, CE, Brazil.
Sampaio LS; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Department of Pathology and Legal Medicine, School of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil.
do Nascimento FBSA; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Department of Pathology and Legal Medicine, School of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil.
da Silva Gaspar B; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
da Cruz Fonseca SG; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
Josino MAA; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Department of Pathology and Legal Medicine, School of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil.
Grangeiro TB; Department of Biology, Science Center, Molecular Genetics Laboratory, Federal University of Ceará, CE, Brazil.
Gaspar DM; Department of Physiology and Pharmacology, Neuropharmacology Laboratory, Federal University of Ceará, Fortaleza, CE, Brazil.
de Lucena DF; Department of Physiology and Pharmacology, Neuropharmacology Laboratory, Federal University of Ceará, Fortaleza, CE, Brazil.
de Moraes MO; Department of Physiology and Pharmacology, Neuropharmacology Laboratory, Federal University of Ceará, Fortaleza, CE, Brazil.
Cavalcanti BC; Department of Physiology and Pharmacology, Neuropharmacology Laboratory, Federal University of Ceará, Fortaleza, CE, Brazil.
Nobre Júnior HV; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil; Department of Pathology and Legal Medicine, School of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil. Electronic address: .
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Źródło :
Microbial pathogenesis [Microb Pathog] 2017 Jun; Vol. 107, pp. 341-348. Date of Electronic Publication: 2017 Apr 12.
Typ publikacji :
Journal Article
MeSH Terms :
Antifungal Agents/*pharmacology
Biofilms/*drug effects
Candida/*drug effects
Drug Resistance, Fungal/*drug effects
Fluconazole/*pharmacology
Serotonin Uptake Inhibitors/*pharmacology
Animals ; Apoptosis/drug effects ; Biofilms/growth & development ; Candida/cytology ; Candida/genetics ; Candida/growth & development ; Cell Count ; Cell Death/drug effects ; Cell Line ; Cell Proliferation/drug effects ; DNA Damage/drug effects ; DNA, Fungal/drug effects ; Fibroblasts/microbiology ; Flow Cytometry ; In Vitro Techniques ; Membrane Potentials ; Mice ; Microbial Sensitivity Tests ; Microbial Viability/drug effects ; Mitochondrial Membranes/drug effects ; Paroxetine/pharmacology ; Plasma/drug effects ; Serotonin Uptake Inhibitors/administration & dosage ; Sertraline/pharmacology
Czasopismo naukowe

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