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Wyświetlanie 1-5 z 5
Tytuł :
Endophytic Actinobacteria from the Brazilian Medicinal Plant Lychnophora ericoides Mart. and the Biological Potential of Their Secondary Metabolites.
Autorzy :
Conti R; Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Avenida do Café s/n, 14040-903, Ribeirão Preto, SP, Brazil.; CEPID-CIBFar - Centro de Pesquisa e Inovação em Biodiversidade e Fármacos, FAPESP, São Paulo, SP, Brazil.
Chagas FO; Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Avenida do Café s/n, 14040-903, Ribeirão Preto, SP, Brazil.; CEPID-CIBFar - Centro de Pesquisa e Inovação em Biodiversidade e Fármacos, FAPESP, São Paulo, SP, Brazil.
Caraballo-Rodriguez AM; Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Avenida do Café s/n, 14040-903, Ribeirão Preto, SP, Brazil.; CEPID-CIBFar - Centro de Pesquisa e Inovação em Biodiversidade e Fármacos, FAPESP, São Paulo, SP, Brazil.
Melo WG; Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Avenida do Café s/n, 14040-903, Ribeirão Preto, SP, Brazil.; CEPID-CIBFar - Centro de Pesquisa e Inovação em Biodiversidade e Fármacos, FAPESP, São Paulo, SP, Brazil.
do Nascimento AM; Instituto de Ciências Exatas e Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil.
Cavalcanti BC; Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE, Brazil.
de Moraes MO; Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE, Brazil.
Pessoa C; Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE, Brazil.; Fundação Oswaldo Cruz (Fiocruz), Fortaleza, CE, Brazil.
Costa-Lotufo LV; Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brazil.
Krogh R; CEPID-CIBFar - Centro de Pesquisa e Inovação em Biodiversidade e Fármacos, FAPESP, São Paulo, SP, Brazil.; Instituto de Física de São Carlos, Universidade de São Paulo, São Carlos, SP, Brazil.
Andricopulo AD; CEPID-CIBFar - Centro de Pesquisa e Inovação em Biodiversidade e Fármacos, FAPESP, São Paulo, SP, Brazil.; Instituto de Física de São Carlos, Universidade de São Paulo, São Carlos, SP, Brazil.
Lopes NP; Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Avenida do Café s/n, 14040-903, Ribeirão Preto, SP, Brazil.
Pupo MT; Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Avenida do Café s/n, 14040-903, Ribeirão Preto, SP, Brazil. .; CEPID-CIBFar - Centro de Pesquisa e Inovação em Biodiversidade e Fármacos, FAPESP, São Paulo, SP, Brazil. .
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Źródło :
Chemistry & biodiversity [Chem Biodivers] 2016 Jun; Vol. 13 (6), pp. 727-36. Date of Electronic Publication: 2016 May 20.
Typ publikacji :
Journal Article
MeSH Terms :
Secondary Metabolism*
Actinobacteria/*isolation & purification
Actinobacteria/*metabolism
Antineoplastic Agents, Phytogenic/*pharmacology
Antiprotozoal Agents/*pharmacology
Asteraceae/*microbiology
Biological Products/*pharmacology
Actinobacteria/chemistry ; Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/isolation & purification ; Antiprotozoal Agents/chemistry ; Antiprotozoal Agents/isolation & purification ; Biological Products/chemistry ; Biological Products/isolation & purification ; Brazil ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Parasitic Sensitivity Tests ; Plants, Medicinal/microbiology ; Structure-Activity Relationship ; Trypanosoma cruzi/drug effects
Czasopismo naukowe
Tytuł :
Synthetic chalcone derivatives as inhibitors of cathepsins K and B, and their cytotoxic evaluation.
Autorzy :
Ramalho SD; Department of Chemistry, State University of Goiás, 495, Anápolis, GO, Brazil; Department of Chemistry, Federal University of São Carlos, 13565-905, São Carlos, SP, Brazil.
Bernades A
Demetrius G
Noda-Perez C
Vieira PC
Dos Santos CY
da Silva JA
de Moraes MO
Mousinho KC
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Źródło :
Chemistry & biodiversity [Chem Biodivers] 2013 Nov; Vol. 10 (11), pp. 1999-2006.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*chemistry
Antineoplastic Agents/*pharmacology
Cathepsin B/*antagonists & inhibitors
Cathepsin K/*antagonists & inhibitors
Chalcone/*analogs & derivatives
Chalcone/*pharmacology
Cathepsin B/metabolism ; Cathepsin K/metabolism ; Cell Line, Tumor ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Humans ; Neoplasms/drug therapy ; Neoplasms/enzymology
Czasopismo naukowe
Tytuł :
Antimicrobial and cytotoxic activities of synthetically derived tambjamines C and E - J, BE-18591, and a related alkaloid from the marine bacterium Pseudoalteromonas tunicata.
Autorzy :
Pinkerton DM; Research School of Chemistry, Institute of Advanced Studies, The Australian National University, Canberra, ACT 0200, Australia.
Banwell MG
Garson MJ
Kumar N
de Moraes MO
Cavalcanti BC
Barros FW
Pessoa C
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Źródło :
Chemistry & biodiversity [Chem Biodivers] 2010 May; Vol. 7 (5), pp. 1311-24.
Typ publikacji :
Journal Article
MeSH Terms :
Alkaloids/*chemistry
Anti-Infective Agents/*chemical synthesis
Cytotoxins/*chemistry
Pseudoalteromonas/*chemistry
Alkaloids/chemical synthesis ; Alkaloids/toxicity ; Animals ; Anti-Infective Agents/chemistry ; Anti-Infective Agents/toxicity ; Cell Line, Tumor ; Cytotoxins/chemical synthesis ; Cytotoxins/toxicity ; Drug Screening Assays, Antitumor ; Erythrocytes/drug effects ; Humans ; Mice ; Microbial Sensitivity Tests ; Pyrroles/chemical synthesis ; Pyrroles/chemistry ; Pyrroles/toxicity
Czasopismo naukowe
Tytuł :
Antitumor activity of the essential oil from the leaves of Croton regelianus and its component ascaridole.
Autorzy :
Bezerra DP; Departamento de Fisiologia e Farmacologia, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, Ceará, Brazil.
Marinho Filho JD
Alves AP
Pessoa C
de Moraes MO
Pessoa OD
Torres MC
Silveira ER
Viana FA
Costa-Lotufo LV
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Źródło :
Chemistry & biodiversity [Chem Biodivers] 2009 Aug; Vol. 6 (8), pp. 1224-31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Monoterpenes/*pharmacology
Oils, Volatile/*pharmacology
Peroxides/*pharmacology
Plant Oils/*pharmacology
Animals ; Cell Line, Tumor ; Croton/chemistry ; Cyclohexane Monoterpenes ; Drug Screening Assays, Antitumor ; Humans ; Mice ; Plant Leaves/chemistry ; Sarcoma 180
Czasopismo naukowe
Tytuł :
Studies on the cytotoxicity of miscellaneous compounds from Eupatorium betonicaeforme (D.C.) Baker (Asteraceae).
Autorzy :
Rocha DD; Departamento de Fisiologia e Farmacologia, Universidade Federal do Ceará, Caixa Postal 3157, 60430-270 Fortaleza, Ceará, Brazil.
Dantas IN
Albuquerque MR
Montenegro RC
Pessoa C
de Moraes MO
Pessoa OD
Silveira ER
Costa-Lotufo LV
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Źródło :
Chemistry & biodiversity [Chem Biodivers] 2007 Dec; Vol. 4 (12), pp. 2835-44.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Asteraceae/*chemistry
Cell Survival/drug effects ; Cells, Cultured ; Humans ; Molecular Structure ; Plant Extracts/chemistry ; Plant Extracts/toxicity
Czasopismo naukowe
    Wyświetlanie 1-5 z 5

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