2-Methoxyestradiol-3,17- O , O -bis-sulfamate (STX140) Inhibits Proliferation and Invasion via Senescence Pathway Induction in Human BRAFi-Resistant Melanoma Cells.
Autorzy:
Franco YA; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, Avenida Professor Lineu Prestes, Butantã 05508-000, São Paulo, Brazil. deMoraesMO Jr; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, Avenida Professor Lineu Prestes, Butantã 05508-000, São Paulo, Brazil. Carvalho LAC; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, Avenida Professor Lineu Prestes, Butantã 05508-000, São Paulo, Brazil. Dohle W; Medicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK. da Silva RO; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, Avenida Professor Lineu Prestes, Butantã 05508-000, São Paulo, Brazil. Noma IHY; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, Avenida Professor Lineu Prestes, Butantã 05508-000, São Paulo, Brazil. Lima K; Department of Pharmacology, Biomedical Sciences Institute, University of São Paulo, Avenida Professor Lineu Prestes, Butantã 05508-000, São Paulo, Brazil. Potter BVL; Medicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK. Machado-Neto JA; Department of Pharmacology, Biomedical Sciences Institute, University of São Paulo, Avenida Professor Lineu Prestes, Butantã 05508-000, São Paulo, Brazil. Maria-Engler SS; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, Avenida Professor Lineu Prestes, Butantã 05508-000, São Paulo, Brazil.
Association of MICA and HLA-B alleles with leprosy in two endemic populations in Brazil.
Autorzy:
Jarduli LR; Department of Clinical Analysis and Biomedicine, Graduate Program in Biosciences and Physiopathology, State University of Maringá, Maringá, Brazil. Alves HV; Department of Clinical Analysis and Biomedicine, Graduate Program in Biosciences and Physiopathology, State University of Maringá, Maringá, Brazil. de Souza VH; Department of Clinical Analysis and Biomedicine, Graduate Program in Biosciences and Physiopathology, State University of Maringá, Maringá, Brazil. Uaska Sartori PV; Graduate Program in Health Sciences, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, Brazil. Fava VM; Infectious Diseases and Immunity in Global Health (IDIGH) Program at the Research Institute of the McGill University Health Centre (RI-MUHC), Montreal, QC, Canada. de Souza FC; Lauro de Souza Lima Institute, Bauru, Brazil. Marcos EVC; Lauro de Souza Lima Institute, Bauru, Brazil. Pereira AC; Lauro de Souza Lima Institute, Bauru, Brazil. Dias-Baptista IMF; Lauro de Souza Lima Institute, Bauru, Brazil. Virmond MDCL; Lauro de Souza Lima Institute, Bauru, Brazil. deMoraesMO; Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Brazil. Mira MT; Graduate Program in Health Sciences, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, Brazil. Visentainer JEL; Graduate Program in Health Sciences, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, Brazil.; Department of Basic Health Sciences, State University of Maringá, Maringá, Brazil.
Evaluation of the cytotoxicity of structurally correlated p-menthane derivatives.
Autorzy:
Andrade LN; Departamento de Fisiologia, Universidade Federal de Sergipe, CEP 49100-000, São Cristóvão-SE, Brazil. . Lima TC; Departamento de Fisiologia, Universidade Federal de Sergipe, CEP 49100-000, São Cristóvão-SE, Brazil. tam_. Amaral RG; Departamento de Fisiologia, Universidade Federal de Sergipe, CEP 49100-000, São Cristóvão-SE, Brazil. . Pessoa Cdo Ó; Departamento de Fisiologia e Farmacologia, Universidade Federal do Ceará, CEP 60430-270, Fortaleza-SE, Brazil. Filho MO; Departamento de Fisiologia e Farmacologia, Universidade Federal do Ceará, CEP 60430-270, Fortaleza-SE, Brazil. . Soares BM; Departamento de Fisiologia e Farmacologia, Universidade Federal do Ceará, CEP 60430-270, Fortaleza-SE, Brazil. . Nascimento LG; Departamento de Ciências Farmacêuticas, Universidade Federal da Paraíba, CP 5009, CEP 58051-970, João Pessoa-PB, Brazil. . Carvalho AA; Farmácia, Universidade Federal de Sergipe, CEP 58051-970, Lagarto-SE, Brazil. . de Sousa DP; Departamento de Ciências Farmacêuticas, Universidade Federal da Paraíba, CP 5009, CEP 58051-970, João Pessoa-PB, Brazil. .
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2015 Jul 21; Vol. 20 (7), pp. 13264-80. Date of Electronic Publication: 2015 Jul 21.
Antifungal activity of naphthoquinoidal compounds in vitro against fluconazole-resistant strains of different Candida species: a special emphasis on mechanisms of action on Candida tropicalis.
Autorzy:
Neto JB; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection and Experiments in Yeast (LABEL), Federal University of Ceará, Fortaleza, Ceará, Brazil. da Silva CR; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection and Experiments in Yeast (LABEL), Federal University of Ceará, Fortaleza, Ceará, Brazil; Department of Pathology and Legal Medicine, School of Medicine, Laboratory of Bioprospection and Experiments in Yeast (LABEL), Federal University of Ceará, Fortaleza, Ceará, Brazil. Neta MA; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection and Experiments in Yeast (LABEL), Federal University of Ceará, Fortaleza, Ceará, Brazil; Department of Pathology and Legal Medicine, School of Medicine, Laboratory of Bioprospection and Experiments in Yeast (LABEL), Federal University of Ceará, Fortaleza, Ceará, Brazil. Campos RS; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection and Experiments in Yeast (LABEL), Federal University of Ceará, Fortaleza, Ceará, Brazil; Department of Pathology and Legal Medicine, School of Medicine, Laboratory of Bioprospection and Experiments in Yeast (LABEL), Federal University of Ceará, Fortaleza, Ceará, Brazil. Siebra JT; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection and Experiments in Yeast (LABEL), Federal University of Ceará, Fortaleza, Ceará, Brazil. Silva RA; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection and Experiments in Yeast (LABEL), Federal University of Ceará, Fortaleza, Ceará, Brazil. Gaspar DM; Department of Physiology and Pharmacology, Laboratory of Experimental Oncology, Federal University of Ceará, Fortaleza, Ceará, Brazil. Magalhães HI; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection and Experiments in Yeast (LABEL), Federal University of Ceará, Fortaleza, Ceará, Brazil; Department of Pharmaceutical Sciences, Center for Toxicological Assistance, University Federal of Paraíba, Paraíba, Brazil. deMoraesMO; Department of Physiology and Pharmacology, Laboratory of Experimental Oncology, Federal University of Ceará, Fortaleza, Ceará, Brazil. Lobo MD; Department of Biology, ScienceCenter, Molecular Genetics Laboratory, Federal University of Ceará, Ceará, Brazil. Grangeiro TB; Department of Biology, ScienceCenter, Molecular Genetics Laboratory, Federal University of Ceará, Ceará, Brazil. Carvalho TS; Natural Products Research Nucleus, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. Diogo EB; Department of Chemistry, Institute of Exact Sciences, Laboratory of Synthetic and Heterocyclic Chemistry, Federal University of Minas Gerais, Minas Gerais, Brazil. da Silva Júnior EN; Department of Chemistry, Institute of Exact Sciences, Laboratory of Synthetic and Heterocyclic Chemistry, Federal University of Minas Gerais, Minas Gerais, Brazil. Rodrigues FA; Department of Physiology and Pharmacology, Laboratory of Experimental Oncology, Federal University of Ceará, Fortaleza, Ceará, Brazil. Cavalcanti BC; Department of Pathology and Legal Medicine, School of Medicine, Laboratory of Bioprospection and Experiments in Yeast (LABEL), Federal University of Ceará, Fortaleza, Ceará, Brazil; Department of Physiology and Pharmacology, Laboratory of Experimental Oncology, Federal University of Ceará, Fortaleza, Ceará, Brazil. Júnior HV; Department of Clinical and Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection and Experiments in Yeast (LABEL), Federal University of Ceará, Fortaleza, Ceará, Brazil; Department of Pathology and Legal Medicine, School of Medicine, Laboratory of Bioprospection and Experiments in Yeast (LABEL), Federal University of Ceará, Fortaleza, Ceará, Brazil; Department of Physiology and Pharmacology, Laboratory of Experimental Oncology, Federal University of Ceará, Fortaleza, Ceará, Brazil.
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Źródło:
PloS one [PLoS One] 2014 May 09; Vol. 9 (5), pp. e93698. Date of Electronic Publication: 2014 May 09 (Print Publication: 2014).
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