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Wyszukujesz frazę ""de Moraes MO"" wg kryterium: Autor


Wyświetlanie 1-9 z 9
Tytuł :
Etomidate is devoid of genotoxicty and mutagenicity in human lymphocytes and in the Salmonella typhimurium/microsomal activation test.
Autorzy :
Cavalcanti BC; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil. Electronic address: .b.
do Amaral Valente Sá LG; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
de Andrade Neto JB; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; Christus University Center (UNICHRISTUS), Fortaleza, CE, Brazil; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
de Sousa Silva AA; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil.
Rios MEF; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.
Barreto FS; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil.
de Oliveira Ferreira JR; School of Medical Sciences, State University of Health Sciences of Alagoas (UNCISAL), AL, Brazil.
da Silva CR; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
Barroso FD; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
Magalhães HIF; Department of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa, PB, Brazil.
Nobre HV Jr; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
de Moraes MO; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil.
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Źródło :
Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2020 Oct; Vol. 68, pp. 104946. Date of Electronic Publication: 2020 Jul 15.
Typ publikacji :
Journal Article
MeSH Terms :
Etomidate/*toxicity
Hypnotics and Sedatives/*toxicity
Lymphocytes/*drug effects
Salmonella typhimurium/*drug effects
Adult ; Animals ; Cell Survival/drug effects ; Cells, Cultured ; DNA Damage ; Erythrocytes/drug effects ; Hemolysis/drug effects ; Humans ; Lymphocytes/metabolism ; Mice ; Mutagenicity Tests ; Salmonella typhimurium/genetics ; Young Adult
Czasopismo naukowe
Tytuł :
Evaluation of Genotoxicity and Mutagenicity of Ketamine on Human Peripheral Blood Leukocytes and in Salmonella typhimurium.
Autorzy :
Cavalcanti BC; Department of Physiology and Pharmacology, Federal University of Ceara, Fortaleza, CE, Brazil; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil. Electronic address: .
de Andrade Neto JB; School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceara, Fortaleza, CE, Brazil; Christus University Center (UNICHRISTUS), Fortaleza, CE, Brazil; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil.
de Sousa Silva AA; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil.
Barreto FS; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil.
de Oliveira Ferreira JR; School of Medical Sciences, State University of Health Sciences of Alagoas (UNCISAL), AL, Brazil.
da Silva CR; School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceara, Fortaleza, CE, Brazil; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil.
Aires do Nascimento FBS; School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceara, Fortaleza, CE, Brazil; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil.
do Amaral Valente Sá LG; School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceara, Fortaleza, CE, Brazil; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil.
Magalhães HIF; Department of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa, PB, Brazil.
Nobre Júnior HV; School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceara, Fortaleza, CE, Brazil; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil.
de Moraes MO; Department of Physiology and Pharmacology, Federal University of Ceara, Fortaleza, CE, Brazil; Drug Research and Development Center, Federal University of Ceara, Fortaleza, CE, Brazil.
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Źródło :
Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2020 Feb; Vol. 62, pp. 104718. Date of Electronic Publication: 2019 Nov 09.
Typ publikacji :
Journal Article
MeSH Terms :
Anesthetics, Dissociative/*toxicity
Ketamine/*toxicity
Leukocytes/*drug effects
Mutagens/*toxicity
Salmonella typhimurium/*drug effects
Salmonella typhimurium/*genetics
Apoptosis/drug effects ; Cell Survival/drug effects ; Chromosome Aberrations/chemically induced ; Comet Assay ; DNA Breaks ; DNA Damage ; Hemolysis/drug effects ; Humans ; Lipid Peroxidation/drug effects ; Mutagenicity Tests ; Oxidative Stress
Czasopismo naukowe
Tytuł :
A novel o-naphtoquinone inhibits N-cadherin expression and blocks melanoma cell invasion via AKT signaling.
Autorzy :
Montenegro RC; Instituto de Ciências Biológicas, Universidade Federal do Pará, Rua Augusto Corrêa 01-Guamá, Belém/PA, Brazil. Electronic address: .
de Vasconcellos MC
Barbosa Gdos S
Burbano RM
Souza LG
Lemos TL
Costa-Lotufo LV
de Moraes MO
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Źródło :
Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2013 Oct; Vol. 27 (7), pp. 2076-83. Date of Electronic Publication: 2013 Aug 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Cadherins/*antagonists & inhibitors
Down-Regulation/*drug effects
Melanoma/*drug therapy
Naphthoquinones/*pharmacology
Proto-Oncogene Proteins c-akt/*antagonists & inhibitors
Signal Transduction/*drug effects
Animals ; Antineoplastic Agents, Phytogenic/adverse effects ; Cadherins/metabolism ; Cell Adhesion/drug effects ; Cell Line ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Survival/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Melanocytes/cytology ; Melanocytes/drug effects ; Melanocytes/metabolism ; Melanoma/metabolism ; Melanoma/pathology ; Mice ; Naphthoquinones/adverse effects ; Neoplasm Proteins/antagonists & inhibitors ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
Growth inhibitory effects of 3'-nitro-3-phenylamino nor-beta-lapachone against HL-60: a redox-dependent mechanism.
Autorzy :
Araújo AJ; Depto. de Fisiologia e Farmacologia, Universidade Federal do Ceará, Fortaleza, CE 60430-270, Brazil.
de Souza AA
da Silva Júnior EN
Marinho-Filho JD
de Moura MA
Rocha DD
Vasconcellos MC
Costa CO
Pessoa C
de Moraes MO
Ferreira VF
de Abreu FC
Pinto AV
Montenegro RC
Costa-Lotufo LV
Goulart MO
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Źródło :
Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2012 Jun; Vol. 26 (4), pp. 585-94. Date of Electronic Publication: 2012 Feb 22.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Benzofurans/*pharmacology
Naphthoquinones/*pharmacology
Apoptosis/drug effects ; Cell Survival/drug effects ; Comet Assay ; DNA Damage ; HL-60 Cells ; Humans ; Oxidation-Reduction ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Caffeine and CSC, adenosine A2A antagonists, offer neuroprotection against 6-OHDA-induced neurotoxicity in rat mesencephalic cells.
Autorzy :
Nobre HV Jr; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza, Brazil.
Cunha GM
de Vasconcelos LM
Magalhães HI
Oliveira Neto RN
Maia FD
de Moraes MO
Leal LK
Viana GS
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Źródło :
Neurochemistry international [Neurochem Int] 2010 Jan; Vol. 56 (1), pp. 51-8. Date of Electronic Publication: 2009 Sep 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenosine A2 Receptor Agonists*
Caffeine/*pharmacology
Neurons/*drug effects
Parkinsonian Disorders/*drug therapy
Substantia Nigra/*drug effects
Xanthines/*pharmacology
Animals ; Apoptosis/drug effects ; Apoptosis/physiology ; Caffeine/therapeutic use ; Cells, Cultured ; Encephalitis/drug therapy ; Encephalitis/metabolism ; Encephalitis/physiopathology ; Female ; Free Radicals/metabolism ; Inflammation Mediators/antagonists & inhibitors ; Inflammation Mediators/metabolism ; Lipid Peroxidation/drug effects ; Lipid Peroxidation/physiology ; Microglia/drug effects ; Microglia/metabolism ; Nerve Degeneration/drug therapy ; Nerve Degeneration/physiopathology ; Nerve Degeneration/prevention & control ; Neurons/metabolism ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Nitrites/metabolism ; Oxidative Stress/drug effects ; Oxidative Stress/physiology ; Oxidopamine/pharmacology ; Parkinsonian Disorders/metabolism ; Parkinsonian Disorders/physiopathology ; Phosphodiesterase Inhibitors/pharmacology ; Phosphodiesterase Inhibitors/therapeutic use ; Rats ; Rats, Wistar ; Receptor, Adenosine A2A/metabolism ; Substantia Nigra/metabolism ; Substantia Nigra/physiopathology ; Sympatholytics/pharmacology ; Xanthines/therapeutic use
Czasopismo naukowe
Tytuł :
Antiproliferative activity of pristimerin isolated from Maytenus ilicifolia (Celastraceae) in human HL-60 cells.
Autorzy :
Costa PM; Departamento de Fisiologia e Farmacologia, Campus do Porangabussu, UFC, Rua Coronel Nunes de Melo, 1127 - Rodolfo Teófilo, Universidade Federal do Ceará, Caixa Postal 3157, 60430-270 Fortaleza, Ceará, Brazil.
Ferreira PM
Bolzani Vda S
Furlan M
de Freitas Formenton Macedo Dos Santos VA
Corsino J
de Moraes MO
Costa-Lotufo LV
Montenegro RC
Pessoa C
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Źródło :
Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2008 Jun; Vol. 22 (4), pp. 854-63. Date of Electronic Publication: 2008 Jan 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation/*drug effects
Leukocytes, Mononuclear/*drug effects
Maytenus/*chemistry
Triterpenes/*pharmacology
Antineoplastic Agents, Phytogenic/administration & dosage ; Antineoplastic Agents, Phytogenic/isolation & purification ; Antineoplastic Agents, Phytogenic/pharmacology ; Apoptosis/drug effects ; DNA Fragmentation/drug effects ; DNA Topoisomerases, Type I/drug effects ; DNA Topoisomerases, Type I/metabolism ; DNA, Neoplasm/biosynthesis ; DNA, Neoplasm/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Flow Cytometry ; HL-60 Cells ; Humans ; Inhibitory Concentration 50 ; Leukocytes, Mononuclear/metabolism ; Necrosis/metabolism ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Plant Roots ; Triterpenes/administration & dosage ; Triterpenes/isolation & purification
Czasopismo naukowe
Tytuł :
Pisosterol induces monocytic differentiation in HL-60 cells.
Autorzy :
Montenegro RC; Laboratório de Oncologia Experimental, Departamento de Fisiologia e Farmacologia, Universidade Federal do Ceará, P.O. Box 3157, 60430-270 Fortaleza, Ceará, Brazil.
de Vasconcellos MC
Silva Bezerra F
Andrade-Neto M
Pessoa C
de Moraes MO
Costa-Lotufo LV
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Źródło :
Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2007 Aug; Vol. 21 (5), pp. 795-800. Date of Electronic Publication: 2007 Jan 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Basidiomycota/*chemistry
Monocytes/*drug effects
Terpenes/*pharmacology
Antimetabolites ; Bromodeoxyuridine ; Cell Differentiation/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; DNA/biosynthesis ; Dose-Response Relationship, Drug ; Fluorescent Dyes ; HL-60 Cells ; Humans ; Naphthol AS D Esterase/metabolism ; Nitroblue Tetrazolium ; Trypan Blue
Czasopismo naukowe
Tytuł :
Piplartine induces inhibition of leukemia cell proliferation triggering both apoptosis and necrosis pathways.
Autorzy :
Bezerra DP; Departamento de Fisiologia e Farmacologia, Faculdade de Medicina, Universidade Federal do Ceará, Caixa Postal 3157, 60430-270 Fortaleza, Ceará, Brazil.
Militão GC
de Castro FO
Pessoa C
de Moraes MO
Silveira ER
Lima MA
Elmiro FJ
Costa-Lotufo LV
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Źródło :
Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2007 Feb; Vol. 21 (1), pp. 1-8. Date of Electronic Publication: 2006 Jul 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Apoptosis/*drug effects
Leukemia/*drug therapy
Piperidones/*pharmacology
Signal Transduction/*drug effects
Caspase 3/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; DNA/biosynthesis ; DNA/genetics ; DNA, Neoplasm/biosynthesis ; DNA, Neoplasm/genetics ; Dose-Response Relationship, Drug ; Enzyme Activation/drug effects ; HL-60 Cells ; Humans ; In Vitro Techniques ; K562 Cells ; Leukemia, T-Cell/drug therapy ; Leukemia, T-Cell/pathology ; Microscopy, Fluorescence ; Monocytes/drug effects ; Necrosis/pathology ; Nucleic Acid Conformation/drug effects ; Piper/chemistry
Czasopismo naukowe
Tytuł :
Antibacterial activity against resistant bacteria and cytotoxicity of four alkaloid toxins isolated from the marine sponge Arenosclera brasiliensis.
Autorzy :
Torres YR; Instituto de Química de São Carlos, Universidade de São Paulo, CP 780, CEP 13560-970, Brazil.
Berlinck RG
Nascimento GG
Fortier SC
Pessoa C
de Moraes MO
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Źródło :
Toxicon : official journal of the International Society on Toxinology [Toxicon] 2002 Jul; Vol. 40 (7), pp. 885-91.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Bacterial*
Macrocyclic Compounds*
Piperidines*
Porifera*/chemistry
Alkaloids/*pharmacology
Anti-Bacterial Agents/*pharmacology
Tumor Cells, Cultured/*drug effects
Alkaloids/isolation & purification ; Animals ; Cell Survival/drug effects ; Formazans/metabolism ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Microbial Sensitivity Tests ; Oligopeptides/isolation & purification ; Oligopeptides/pharmacology ; Tetrazolium Salts/metabolism ; Tumor Cells, Cultured/metabolism ; Tumor Cells, Cultured/pathology
Czasopismo naukowe
    Wyświetlanie 1-9 z 9

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