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Tytuł:
P2X7 Receptor-Induced Human Mast Cell Degranulation Is Enhanced by Interleukin 33.
Autorzy:
Salcman B; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9NT, UK.
Bahri R; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9NT, UK.
West PW; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9NT, UK.
Tontini C; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9NT, UK.
Affleck K; GlaxoSmithKline, Stevenage SG1 2NY, UK.
Bulfone-Paus S; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester M13 9NT, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 31; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 31.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Degranulation*/genetics
Cell Degranulation*/physiology
Interleukin-33*/pharmacology
Interleukin-33*/metabolism
Receptors, Purinergic P2X7*/metabolism
Humans ; Adenosine Triphosphate/pharmacology ; Adenosine Triphosphate/metabolism ; Mast Cells/metabolism ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HIV vaccines induce CD8 T cells with low antigen receptor sensitivity.
Autorzy:
Migueles SA; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Nettere DM; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Gavil NV; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Wang LT; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Toulmin SA; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Kelly EP; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Ward AJ; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Lin S; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Thompson SA; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Peterson BA; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Abdeen CS; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Sclafani CR; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Pryal PF; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Leach BG; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Ludwig AK; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Rogan DC; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Przygonska PA; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Cattani A; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Imamichi H; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Sachs A; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Cafri G; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Huang NN; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Patamawenu A; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Liang CJ; Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Hallahan CW; Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Kambach DM; Agilent Technologies, Inc., Santa Clara, CA, USA.
Han EX; IsoPlexis, Inc., Branford, CT, USA.
Coupet T; IsoPlexis, Inc., Branford, CT, USA.
Chen J; IsoPlexis, Inc., Branford, CT, USA.
Moir SL; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Chun TW; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Coates EE; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Ledgerwood J; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Schmidt J; Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland.; Department of Oncology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Taillandier-Coindard M; Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland.; Department of Oncology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Michaux J; Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland.; Department of Oncology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Pak H; Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland.; Department of Oncology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Bassani-Sternberg M; Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland.; Department of Oncology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Frahm N; Vaccine and Infectious Disease Division and the HIV Vaccine Trials Network, Fred Hutchinson Cancer Center, Seattle, WA, USA.
McElrath MJ; Vaccine and Infectious Disease Division and the HIV Vaccine Trials Network, Fred Hutchinson Cancer Center, Seattle, WA, USA.
Connors M; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Dec 15; Vol. 382 (6676), pp. 1270-1276. Date of Electronic Publication: 2023 Dec 14.
Typ publikacji:
Journal Article
MeSH Terms:
AIDS Vaccines*/immunology
HIV Infections*/prevention & control
Cytotoxicity, Immunologic*
T-Lymphocytes, Cytotoxic*/immunology
Cell Degranulation*/immunology
Humans ; Clone Cells ; Receptors, Antigen, T-Cell/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Neutrophil-like cells derived from the HL-60 cell-line as a genetically-tractable model for neutrophil degranulation.
Autorzy:
Bhakta SB; Department of Biological Sciences, California State Polytechnic University Pomona, Pomona, CA, United States of America.
Lundgren SM; Department of Microbiology and Molecular Genetics, University of California Davis, Davis, CA, United States of America.
Sesti BN; Department of Biological Sciences, California State Polytechnic University Pomona, Pomona, CA, United States of America.
Flores BA; Department of Biological Sciences, California State Polytechnic University Pomona, Pomona, CA, United States of America.
Akdogan E; Department of Microbiology and Molecular Genetics, University of California Davis, Davis, CA, United States of America.
Collins SR; Department of Microbiology and Molecular Genetics, University of California Davis, Davis, CA, United States of America.
Mercer F; Department of Biological Sciences, California State Polytechnic University Pomona, Pomona, CA, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Feb 07; Vol. 19 (2), pp. e0297758. Date of Electronic Publication: 2024 Feb 07 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Neutrophils*/metabolism
Phagocytosis*
Humans ; HL-60 Cells ; Cell Differentiation/physiology ; Granulocyte Precursor Cells ; Cell Degranulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Distinct Effects of the Mitochondria-Targeted STAT3 Inhibitors Mitocur-1 and Mitocur-3 on Mast Cell and Mitochondrial Functions.
Autorzy:
Pavlyuchenkova AN; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119234 Moscow, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Chelombitko MA; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; The 'Russian Clinical Research Center for Gerontology', Ministry of Healthcare of the Russian Federation, Pirogov Russian National Research Medical University, 129226 Moscow, Russia.
Fedorov AV; Department of Cell Biology and Histology, Biology Faculty, Lomonosov Moscow State University, 119234 Moscow, Russia.
Kuznetsova MK; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119234 Moscow, Russia.
Zinovkin RA; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; The 'Russian Clinical Research Center for Gerontology', Ministry of Healthcare of the Russian Federation, Pirogov Russian National Research Medical University, 129226 Moscow, Russia.
Razin E; Department of Biochemistry and Molecular Biology, The Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 12; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 12.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Degranulation*
Mast Cells*/metabolism
Rats ; Animals ; Reactive Oxygen Species/metabolism ; AMP-Activated Protein Kinases/metabolism ; Antigens/metabolism ; Mitochondria
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Arf1 facilitates mast cell proliferation via the mTORC1 pathway.
Autorzy:
Kotani Y; Department of Cell Signaling, Institute of Biomedical Science, Kansai Medical University, Hirakata, Osaka, 573-1010, Japan.; Department of Biological Science, Graduate School of Humanities and Sciences, Nara Women's University, Nara, 630-8506, Japan.
Sumiyoshi M; Department of Cell Signaling, Institute of Biomedical Science, Kansai Medical University, Hirakata, Osaka, 573-1010, Japan.
Sasada M; Department of Biological Science, Graduate School of Humanities and Sciences, Nara Women's University, Nara, 630-8506, Japan.
Watanabe T; Department of Biological Science, Graduate School of Humanities and Sciences, Nara Women's University, Nara, 630-8506, Japan. .
Matsuda S; Department of Cell Signaling, Institute of Biomedical Science, Kansai Medical University, Hirakata, Osaka, 573-1010, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2022 Dec 24; Vol. 12 (1), pp. 22297. Date of Electronic Publication: 2022 Dec 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Degranulation*/genetics
ADP-Ribosylation Factor 1*/genetics
ADP-Ribosylation Factor 1*/metabolism
Mechanistic Target of Rapamycin Complex 1/metabolism ; Receptors, IgE/metabolism ; Cytokines/metabolism ; Cell Proliferation ; Mast Cells/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
P2X4 receptor stimulation enhances MrgprB2-mediated mast cell activation and pseudoallergic reactions in mice.
Autorzy:
Yoshida K; Laboratory of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki-shi, Gunma, 370-0033, Japan. .
Tanihara S; Laboratory of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki-shi, Gunma, 370-0033, Japan.
Miyashita Y; Laboratory of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki-shi, Gunma, 370-0033, Japan.
Obayashi K; Laboratory of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki-shi, Gunma, 370-0033, Japan.
Ito MA; Laboratory of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki-shi, Gunma, 370-0033, Japan.
Yamamoto K; Department of Biomedical Engineering, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-0033, Japan.
Imai T; Discovery Research Laboratories, Nippon Chemiphar Co., Ltd., Misato, Saitama, 341-0005, Japan.
Matsuoka I; Laboratory of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki-shi, Gunma, 370-0033, Japan.
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Źródło:
Scientific reports [Sci Rep] 2022 Nov 03; Vol. 12 (1), pp. 18613. Date of Electronic Publication: 2022 Nov 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Degranulation*
Anaphylaxis*/chemically induced
Mice ; Humans ; Animals ; Mast Cells/metabolism ; Receptors, Neuropeptide/genetics ; Receptors, Neuropeptide/metabolism ; Receptors, Purinergic P2X4 ; Phosphatidylinositol 3-Kinases ; Mice, Inbred C57BL ; Nerve Tissue Proteins/metabolism ; Receptors, G-Protein-Coupled/genetics ; Receptors, G-Protein-Coupled/metabolism ; Adenosine Triphosphate/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Editorial comment on "The basophil activation test has high reproducibility and is feasible in the clinical setting".
Autorzy:
Fernandez-Santamaria R; Allergy Research Group, Instituto de Investigación Biomédica de Málaga- IBIMA, Málaga, Spain.; Departmento de Medicina, Universidad de Málaga-UMA, Málaga, Spain.
Riggioni C; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore City, Singapore.
Peters RL; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Department of Paediatrics, The University of Melbourne, Melbourne, Victoria, Australia.
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Źródło:
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology [Pediatr Allergy Immunol] 2022 Nov; Vol. 33 (11), pp. e13879.
Typ publikacji:
Editorial
MeSH Terms:
Basophil Degranulation Test*
Basophils*
Humans ; Reproducibility of Results ; Immunoglobulin E
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibition of Complex I of the Respiratory Chain, but Not Complex III, Attenuates Degranulation and Cytokine Secretion in Human Skin Mast Cells.
Autorzy:
Buttgereit T; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, 12203 Berlin, Germany.
Pfeiffenberger M; Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.; German Rheumatism Research Centre (DRFZ) Berlin, a Leibniz Institute, 10117 Berlin, Germany.
Frischbutter S; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, 12203 Berlin, Germany.
Krauß PL; Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.; German Rheumatism Research Centre (DRFZ) Berlin, a Leibniz Institute, 10117 Berlin, Germany.
Chen Y; Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.; German Rheumatism Research Centre (DRFZ) Berlin, a Leibniz Institute, 10117 Berlin, Germany.
Maurer M; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, 12203 Berlin, Germany.
Buttgereit F; Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.
Gaber T; Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.; German Rheumatism Research Centre (DRFZ) Berlin, a Leibniz Institute, 10117 Berlin, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 30; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 30.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Degranulation*
Mast Cells*/metabolism
Electron Transport ; Electron Transport Complex I/metabolism ; Glucose/metabolism ; Granulocyte-Macrophage Colony-Stimulating Factor/metabolism ; Humans ; Immunoglobulin E ; Interleukin-13/metabolism ; Interleukin-4/metabolism ; Interleukin-6/metabolism ; Methacrylates ; Rotenone/metabolism ; Rotenone/pharmacology ; Thiazoles ; Tumor Necrosis Factor-alpha/metabolism ; beta-N-Acetylhexosaminidases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Basophil activation test has high reproducibility and is feasible in the clinical setting.
Autorzy:
Jaumdally H; Department of Women and Children's Health (Pediatric Allergy), School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.; Children's Allergy Service, Evelina London Children's Hospital, Guy's and St Thomas' Hospital, London, UK.
Kwok M; Department of Women and Children's Health (Pediatric Allergy), School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.; Asthma UK Centre in Allergic Mechanisms of Asthma, London, UK.
Jama Z; Department of Women and Children's Health (Pediatric Allergy), School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.; Asthma UK Centre in Allergic Mechanisms of Asthma, London, UK.
Hesse-Lamptey R; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.
McKendry R; Department of Women and Children's Health (Pediatric Allergy), School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.; Asthma UK Centre in Allergic Mechanisms of Asthma, London, UK.
Galvez O; Viapath, Special Haematology Laboratory, London, UK.
Daniel Y; Viapath, Special Haematology Laboratory, London, UK.
Santos AF; Department of Women and Children's Health (Pediatric Allergy), School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.; Children's Allergy Service, Evelina London Children's Hospital, Guy's and St Thomas' Hospital, London, UK.; Asthma UK Centre in Allergic Mechanisms of Asthma, London, UK.
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Źródło:
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology [Pediatr Allergy Immunol] 2022 Oct; Vol. 33 (11), pp. e13870.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Basophil Degranulation Test*
Peanut Hypersensitivity*/diagnosis
Child ; Humans ; Reproducibility of Results ; Arachis ; Food
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
RORα overexpression reduced interleukin-33 expression and prevented mast cell degranulation and inflammation by inducing autophagy in allergic rhinitis.
Autorzy:
Yu W; Department of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.; Department of Otolaryngology-Head and Neck Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Du J; Department of Otolaryngology-Head and Neck Surgery, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, Sichuan, China.
Peng L; Department of Microbiology and Immunology, School of Basic Medical Sciences，North Sichuan Medical College, Nanchong, Sichuan, China.
Zhang T; Department of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.
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Źródło:
Immunity, inflammation and disease [Immun Inflamm Dis] 2023 Oct; Vol. 11 (10), pp. e1017.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mast Cells*/pathology
Rhinitis, Allergic*/pathology
Animals ; Humans ; Mice ; Autophagy ; Cell Degranulation ; Inflammasomes/metabolism ; Inflammation ; Interleukin-33 ; NLR Family, Pyrin Domain-Containing 3 Protein
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Case of Polyethylene Glycol Allergy Confirmed with Basophil Activation Test and Oral Challenge Successfully Immunized with SARS-CoV-2 Vaccine.
Autorzy:
Pasali M; Allergy Unit 'D. Kalogeromitros', 2nd Department of Dermatology and Venereology, National and Kapodistrian University of Athens, ATTIKON University General Hospital, Athens, Greece. .
Taka S; Allergy and Clinical Immunology Unit, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, Athens, Greece 3 StArtBioP.C., Molecular Allergy Diagnostics, Athens, Greece. .
Chliva C; Allergy Unit 'D. Kalogeromitros', 2nd Department of Dermatology and Venereology, National and Kapodistrian University of Athens, ATTIKON University General Hospital, Athens, Greece. .
Katoulis A; 2nd Dpt. of Dermatology and Venereology, National and Kapodistrian University of Athens, ATTIKON University General Hospital, Athens, Greece. .
Makris M; 2nd Department of Dermatology and Venereology, National and Kapodistrian University of Athens, ATTIKON University General Hospital, Athens, Greece. .
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Źródło:
Iranian journal of allergy, asthma, and immunology [Iran J Allergy Asthma Immunol] 2023 Sep 03; Vol. 22 (4), pp. 409-412. Date of Electronic Publication: 2023 Sep 03.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Anaphylaxis*
COVID-19*/diagnosis
COVID-19*/prevention & control
COVID-19 Vaccines*/administration & dosage
Polyethylene Glycols*/adverse effects
Adult ; Female ; Humans ; Basophil Degranulation Test ; Polysorbates/adverse effects ; SARS-CoV-2
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Basophil Activation Test Utility as a Diagnostic Tool in LTP Allergy.
Autorzy:
Cañas JA; Allergy Research Group, Instituto de Investigación Biomédica de Málaga-IBIMA, 29009 Malaga, Spain.; Andalusian Centre for Nanomedicine and Biotechnology-BIONAND, 29590 Malaga, Spain.
Pérez-Sánchez N; Allergy Clinical Unit, Hospital Regional Universitario de Málaga, 29009 Malaga, Spain.
Lopera-Doblas L; Allergy Research Group, Instituto de Investigación Biomédica de Málaga-IBIMA, 29009 Malaga, Spain.
Palomares F; Allergy Research Group, Instituto de Investigación Biomédica de Málaga-IBIMA, 29009 Malaga, Spain.
Molina A; Allergy Research Group, Instituto de Investigación Biomédica de Málaga-IBIMA, 29009 Malaga, Spain.
Bartra J; Allergy Section, Pulmonology, Hospital Clinic, University of Barcelona, 08036 Barcelona, Spain.; Clinical & Experimental Respiratory Immunoallergy (IRCE), Instituto de Investigaciones Biomédicas Pi I Sunyer (IDIBAPS)-ARADyAL, 08036 Barcelona, Spain.
Torres MJ; Andalusian Centre for Nanomedicine and Biotechnology-BIONAND, 29590 Malaga, Spain.; Allergy Clinical Unit, Hospital Regional Universitario de Málaga, 29009 Malaga, Spain.; Medicine Department, University of Malaga-UMA, 29010 Malaga, Spain.
Gómez F; Allergy Clinical Unit, Hospital Regional Universitario de Málaga, 29009 Malaga, Spain.
Mayorga C; Allergy Research Group, Instituto de Investigación Biomédica de Málaga-IBIMA, 29009 Malaga, Spain.; Andalusian Centre for Nanomedicine and Biotechnology-BIONAND, 29590 Malaga, Spain.; Allergy Clinical Unit, Hospital Regional Universitario de Málaga, 29009 Malaga, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Apr 29; Vol. 23 (9). Date of Electronic Publication: 2022 Apr 29.
Typ publikacji:
Journal Article
MeSH Terms:
Basophil Degranulation Test*/methods
Food Hypersensitivity*/diagnosis
Food Hypersensitivity*/metabolism
Allergens/metabolism ; Arachis ; Basophils ; Humans ; Immunoglobulin E/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synergistic Cytokine Production by ATP and PGE 2 via P2X4 and EP 3 Receptors in Mouse Bone-Marrow-Derived Mast Cells.
Autorzy:
Obayashi K; Laboratory of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki 370-0033, Gunma, Japan.
Yoshida K; Laboratory of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki 370-0033, Gunma, Japan.
Ito MA; Laboratory of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki 370-0033, Gunma, Japan.
Mori T; Laboratory of Allergy and Immunology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki 370-0033, Gunma, Japan.
Yamamoto K; Department of Biomedical Engineering, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.
Imai T; Discovery Research Laboratories, Nippon Chemiphar Co., Ltd., Misato 341-0005, Saitama, Japan.
Matsuoka I; Laboratory of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki 370-0033, Gunma, Japan.
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Źródło:
Cells [Cells] 2022 Feb 10; Vol. 11 (4). Date of Electronic Publication: 2022 Feb 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Degranulation*
Cytokines*/metabolism
Mast Cells*/metabolism
Receptors, Prostaglandin E, EP3 Subtype*/metabolism
Receptors, Purinergic P2X4*/metabolism
Adenosine Triphosphate/metabolism ; Animals ; Bone Marrow/metabolism ; Dinoprostone/metabolism ; Gene Expression ; Interleukin-6/metabolism ; Mice ; RNA, Messenger/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Egusi seed allergy confirmed using the basophil activation test.
Autorzy:
Harnik E; Children's Allergies Department, Guy's and St Thomas' Hospital NHS Foundation Trust, London, UK.
Jama Z; Department of Women and Children's Health (Paediatric Allergy, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.; MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, UK.
Kwok M; Department of Women and Children's Health (Paediatric Allergy, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.; MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, UK.
Fox AT; Children's Allergies Department, Guy's and St Thomas' Hospital NHS Foundation Trust, London, UK.; Department of Women and Children's Health (Paediatric Allergy, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Santos AF; Children's Allergies Department, Guy's and St Thomas' Hospital NHS Foundation Trust, London, UK.; Department of Women and Children's Health (Paediatric Allergy, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.; MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, UK.
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Źródło:
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology [Pediatr Allergy Immunol] 2022 Jan; Vol. 33 (1), pp. e13716. Date of Electronic Publication: 2021 Dec 20.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
Basophil Degranulation Test*
Hypersensitivity*
Allergens ; Basophils ; Humans ; Seeds
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In vitro prediction of in vivo pseudo-allergenic response via MRGPRX2.
Autorzy:
John LM; Global Research, Novo Nordisk A/S, Maaloev, Denmark.
Dalsgaard CM; Global Research, Novo Nordisk A/S, Maaloev, Denmark.
Jeppesen CB; Global Research, Novo Nordisk A/S, Maaloev, Denmark.
Conde-Frieboes KW; Global Research, Novo Nordisk A/S, Maaloev, Denmark.
Baumann K; RefLab ApS, Copenhagen N, Denmark.
Knudsen NPH; RefLab ApS, Copenhagen N, Denmark.
Skov PS; RefLab ApS, Copenhagen N, Denmark.; Odense Research Center of Anaphylaxis, Odense University Hospital, Odense, Denmark.
Wulff BS; Global Research, Novo Nordisk A/S, Maaloev, Denmark.
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Źródło:
Journal of immunotoxicology [J Immunotoxicol] 2021 Dec; Vol. 18 (1), pp. 30-36.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Degranulation*
Receptors, Neuropeptide*
Allergens ; Animals ; Humans ; Mast Cells ; Nerve Tissue Proteins ; Rats ; Receptors, G-Protein-Coupled
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transcriptome-based analysis of blood samples reveals elevation of DNA damage response, neutrophil degranulation, cancer and neurodegenerative pathways in Plasmodium falciparum patients.
Autorzy:
Karikari AA; Department of Biomedical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.
Wruck W; Institute for Stem Cell Research and Regenerative Medicine, Medical Faculty, Heinrich-Heine University, 40225, Düsseldorf, Germany.
Adjaye J; Institute for Stem Cell Research and Regenerative Medicine, Medical Faculty, Heinrich-Heine University, 40225, Düsseldorf, Germany. .
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Źródło:
Malaria journal [Malar J] 2021 Sep 26; Vol. 20 (1), pp. 383. Date of Electronic Publication: 2021 Sep 26.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Degranulation*
DNA Damage*
Transcriptome*
Malaria, Falciparum/*physiopathology
Neutrophils/*physiology
Plasmodium falciparum/*physiology
Dried Blood Spot Testing ; Malaria, Falciparum/complications ; Malaria, Falciparum/parasitology ; Neoplasms/complications ; Neurodegenerative Diseases/complications
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Enigma of Eosinophil Degranulation.
Autorzy:
Fettrelet T; Institute of Pharmacology, University of Bern, Inselspital, INO-F, CH-3010 Bern, Switzerland.; Department of Biochemistry, University of Lausanne, CH-1066 Epalinges, Switzerland.
Gigon L; Institute of Pharmacology, University of Bern, Inselspital, INO-F, CH-3010 Bern, Switzerland.
Karaulov A; Department of Clinical Immunology and Allergology, Sechenov University, 119991 Moscow, Russia.
Yousefi S; Institute of Pharmacology, University of Bern, Inselspital, INO-F, CH-3010 Bern, Switzerland.
Simon HU; Institute of Pharmacology, University of Bern, Inselspital, INO-F, CH-3010 Bern, Switzerland.; Department of Clinical Immunology and Allergology, Sechenov University, 119991 Moscow, Russia.; Laboratory of Molecular Immunology, Institute of Fundamental Medicine and Biology, Kazan Federal University, 420012 Kazan, Russia.; Institute of Biochemistry, Medical School Brandenburg, D-16816 Neuruppin, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 30; Vol. 22 (13). Date of Electronic Publication: 2021 Jun 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cell Degranulation*
Eosinophils/*metabolism
Extracellular Traps/*metabolism
Hypersensitivity/*metabolism
Eosinophils/pathology ; Humans ; Hypersensitivity/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Role of Neutrophils on the Ocular Surface.
Autorzy:
Mun Y; Department of Ophthalmology, Hallym University Medical Center, Hallym University College of Medicine, Seoul 07442, Korea.; Hallym BioEyeTech Research Center, Hallym University College of Medicine, Seoul 07442, Korea.
Hwang JS; Department of Ophthalmology, Hallym University Medical Center, Hallym University College of Medicine, Seoul 07442, Korea.; Hallym BioEyeTech Research Center, Hallym University College of Medicine, Seoul 07442, Korea.
Shin YJ; Department of Ophthalmology, Hallym University Medical Center, Hallym University College of Medicine, Seoul 07442, Korea.; Hallym BioEyeTech Research Center, Hallym University College of Medicine, Seoul 07442, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 27; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 27.
Typ publikacji:
Journal Article; Systematic Review
MeSH Terms:
Cell Degranulation*
Neutrophil Infiltration*
Cornea/*metabolism
Extracellular Traps/*metabolism
Eye Diseases/*metabolism
Neutrophils/*metabolism
Cornea/pathology ; Eye Diseases/pathology ; Humans ; Neutrophils/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Degranulation enhances presynaptic membrane packing, which protects NK cells from perforin-mediated autolysis.
Autorzy:
Li Y; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America.; Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, New York, United States of America.
Orange JS; Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, New York, United States of America.
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Źródło:
PLoS biology [PLoS Biol] 2021 Aug 03; Vol. 19 (8), pp. e3001328. Date of Electronic Publication: 2021 Aug 03 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Cell Degranulation*
Killer Cells, Natural/*physiology
Membrane Lipids/*metabolism
Perforin/*metabolism
Cell Line, Tumor ; Cell Survival ; Healthy Volunteers ; Humans ; Ketocholesterols ; Primary Cell Culture
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Wheatgrass-and-Aronia-Mixed Extract Suppresses Immunoglobulin E-Mediated Allergic Reactions In Vitro and In Vivo.
Autorzy:
Lee JH; Department of Immunology, Jeonbuk National University Medical School, Jeonju-si 54907, Republic of Korea.
Lim JY; Department of Immunology, Jeonbuk National University Medical School, Jeonju-si 54907, Republic of Korea.
Jeon YD; Department of Korean Pharmacy, Woosuk University, Wanju-Gun, Samnye-eup 55338, Republic of Korea.
Yun DH; Department of Health Administration, Kwangju Women's University, Kwangju 62396, Republic of Korea.
Lee YM; Department of Oriental Pharmacy, College of Pharmacy, Wonkwang-Oriental Medicines Research Institute, Wonkwang University, Iksan 54538, Republic of Korea.
Kim DK; Department of Immunology, Jeonbuk National University Medical School, Jeonju-si 54907, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 26; Vol. 24 (15). Date of Electronic Publication: 2023 Jul 26.
Typ publikacji:
Journal Article
MeSH Terms:
Photinia*
Hypersensitivity*
Anti-Allergic Agents*/pharmacology
Anti-Allergic Agents*/therapeutic use
Anti-Allergic Agents*/metabolism
Anaphylaxis*
Mice ; Animals ; Immunoglobulin E ; Cytokines/metabolism ; Mast Cells/metabolism ; Cell Degranulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 4958

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