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Tytuł :
Quercetin ameliorates oxidative stress‑induced cell apoptosis of seminal vesicles via activating Nrf2 in type 1 diabetic rats.
Autorzy :
Dong B; Medical College of Soochow University, Suzhou, China; Department of Urology, Xuzhou Central Hospital, Xuzhou, China; Department of Urology, Suining People's Hospital, Xuzhou, China.
Shi Z; Department of Urology, Xuzhou Central Hospital, Xuzhou, China.
Dong Y; Medical College of Soochow University, Suzhou, China; Department of Urology, Xuzhou Central Hospital, Xuzhou, China.
Chen J; Medical College of Soochow University, Suzhou, China.
Wu ZX; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York, USA.
Wu W; Medical College of Soochow University, Suzhou, China.
Chen ZS; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York, USA. Electronic address: .
Han C; Medical College of Soochow University, Suzhou, China; Department of Urology, Xuzhou Central Hospital, Xuzhou, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Jul; Vol. 151, pp. 113108. Date of Electronic Publication: 2022 May 17.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*/drug effects
Apoptosis*/physiology
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/metabolism
NF-E2-Related Factor 2*/metabolism
Quercetin*/metabolism
Quercetin*/pharmacology
Quercetin*/therapeutic use
Seminal Vesicles*/drug effects
Seminal Vesicles*/metabolism
Animals ; Antioxidants/metabolism ; Blood Glucose/metabolism ; Diabetes Mellitus, Type 1/drug therapy ; Diabetes Mellitus, Type 1/metabolism ; GA-Binding Protein Transcription Factor/metabolism ; Male ; Oxidative Stress/drug effects ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Rats ; Rats, Sprague-Dawley ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł :
The efficacy of a paeoniflorin-sodium alginate-gelatin skin scaffold for the treatment of diabetic wound: An in vivo study in a rat model.
Autorzy :
Yu H; Department of Interventional and Vascular Surgery, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou 213003, China.
Gong W; Department of Pathology, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou 213003, China.
Mei J; Department of Interventional and Vascular Surgery, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou 213003, China.
Qin L; Department of Interventional and Vascular Surgery, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou 213003, China.
Piao Z; Department of Interventional and Vascular Surgery, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou 213003, China.
You D; Department of Radiology, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou 213003, China.
Gu W; Department of Pathology, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou 213003, China. Electronic address: .
Jia Z; Department of Interventional and Vascular Surgery, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou 213003, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Jul; Vol. 151, pp. 113165. Date of Electronic Publication: 2022 May 24.
Typ publikacji :
Journal Article
MeSH Terms :
Alginates*/administration & dosage
Alginates*/therapeutic use
Diabetes Complications*/complications
Diabetes Complications*/therapy
Gelatin*/administration & dosage
Gelatin*/therapeutic use
Glucosides*/administration & dosage
Glucosides*/therapeutic use
Skin*/blood supply
Skin*/drug effects
Skin*/injuries
Tissue Scaffolds*
Animals ; Collagen/metabolism ; Diabetes Mellitus ; Disease Models, Animal ; Microvessels/drug effects ; Microvessels/physiology ; Monoterpenes/administration & dosage ; Monoterpenes/therapeutic use ; Printing, Three-Dimensional ; Rats ; Wound Healing/drug effects ; Wound Healing/physiology ; Wounds and Injuries/complications ; Wounds and Injuries/physiopathology ; Wounds and Injuries/therapy
Czasopismo naukowe
Tytuł :
Potential Influence of Age and Diabetes Mellitus Type 1 on MSH2 (MutS homolog 2) Expression in a Rat Kidney Tissue.
Autorzy :
Babić P; Department of Medicine, University Hospital Dubrava, 10 000 Zagreb, Croatia.
Filipović N; Department of Anatomy, Histology and Embryology, University of Split School of Medicine, 21 000 Split, Croatia.
Hamzić LF; Center for Applied Bioanthropology, Institute for Anthropological Research, 10 000 Zagreb, Croatia.
Puljak L; Center for Evidence-Based Medicine, Catholic University of Croatia, 10 000 Zagreb, Croatia.
Vukojević K; Department of Anatomy, Histology and Embryology, University of Split School of Medicine, 21 000 Split, Croatia.
Benzon B; Department of Anatomy, Histology and Embryology, University of Split School of Medicine, 21 000 Split, Croatia.
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Źródło :
Genes [Genes (Basel)] 2022 Jun 13; Vol. 13 (6). Date of Electronic Publication: 2022 Jun 13.
Typ publikacji :
Journal Article
MeSH Terms :
Aging*
Diabetes Mellitus, Experimental*/genetics
MutS Homolog 2 Protein*/genetics
Animals ; Diabetes Mellitus, Type 1/genetics ; Down-Regulation ; Kidney/metabolism ; Proteins/genetics ; Rats
Czasopismo naukowe
Tytuł :
miR-146a promotes M2 macrophage polarization and accelerates diabetic wound healing by inhibiting the TLR4/NF-κB axis.
Autorzy :
Peng X; Department of Endocrinology, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, People's Republic of China.
He F; Department of Endocrinology, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, People's Republic of China.
Mao Y; Department of Endocrinology, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, People's Republic of China.
Lin Y; Department of Endocrinology, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, People's Republic of China.
Fang J; Department of Endocrinology, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, People's Republic of China.
Chen Y; Department of Nuclear Medicine, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, People's Republic of China.
Sun Z; Department of Endocrinology, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, People's Republic of China.
Zhuo Y; Department of Endocrinology, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, People's Republic of China.
Jiang J; Department of Endocrinology, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, People's Republic of China.
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Źródło :
Journal of molecular endocrinology [J Mol Endocrinol] 2022 May 23; Vol. 69 (2), pp. 315-327. Date of Electronic Publication: 2022 May 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Complications*/metabolism
Macrophage Activation*
MicroRNAs*/genetics
MicroRNAs*/metabolism
Wound Healing*/genetics
Animals ; Diabetes Mellitus/metabolism ; Humans ; Macrophages/metabolism ; Mice ; NF-kappa B/metabolism ; Toll-Like Receptor 4/genetics ; Toll-Like Receptor 4/metabolism ; Ulcer/metabolism
Czasopismo naukowe
Tytuł :
Time series of diabetes attributable mortality from 2008 to 2017.
Autorzy :
Fedeli U; Epidemiological Department, Azienda Zero, Veneto Region, Italy.
Schievano E; Epidemiological Department, Azienda Zero, Veneto Region, Italy.
Masotto S; Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Hospital Trust of Verona, Università di Verona, Piazzale Stefani, 1, 37126, Verona, Italy.
Bonora E; Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Hospital Trust of Verona, Università di Verona, Piazzale Stefani, 1, 37126, Verona, Italy.
Zoppini G; Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Hospital Trust of Verona, Università di Verona, Piazzale Stefani, 1, 37126, Verona, Italy. .
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Źródło :
Journal of endocrinological investigation [J Endocrinol Invest] 2022 Feb; Vol. 45 (2), pp. 275-278. Date of Electronic Publication: 2021 Sep 30.
Typ publikacji :
Journal Article
MeSH Terms :
Cardiovascular Diseases*/diagnosis
Cardiovascular Diseases*/etiology
Cardiovascular Diseases*/mortality
Diabetes Complications*/diagnosis
Diabetes Complications*/mortality
Diabetes Mellitus/*mortality
Mortality/*trends
Cause of Death/trends ; Death Certificates ; Diabetes Mellitus/diagnosis ; Diabetes Mellitus/prevention & control ; Female ; Humans ; Italy/epidemiology ; Male ; Middle Aged ; Sex Factors
Czasopismo naukowe
Tytuł :
Effect of spermidine on ameliorating spermatogenic disorders in diabetic mice via regulating glycolysis pathway.
Autorzy :
Wang JY; Clinical Anatomy & Reproductive Medicine Application Institute, Heng Yang Medical College, University of South China, Hengyang, 421001, Hunan, China.
Ma D; Clinical Anatomy & Reproductive Medicine Application Institute, Heng Yang Medical College, University of South China, Hengyang, 421001, Hunan, China.
Luo M; Clinical Anatomy & Reproductive Medicine Application Institute, Heng Yang Medical College, University of South China, Hengyang, 421001, Hunan, China.
Tan YP; Clinical Anatomy & Reproductive Medicine Application Institute, Heng Yang Medical College, University of South China, Hengyang, 421001, Hunan, China.
Ou Zhong; Clinical Anatomy & Reproductive Medicine Application Institute, Heng Yang Medical College, University of South China, Hengyang, 421001, Hunan, China.
Tian G; Clinical Anatomy & Reproductive Medicine Application Institute, Heng Yang Medical College, University of South China, Hengyang, 421001, Hunan, China.
Lv YT; Clinical Anatomy & Reproductive Medicine Application Institute, Heng Yang Medical College, University of South China, Hengyang, 421001, Hunan, China.
Li MX; Clinical Anatomy & Reproductive Medicine Application Institute, Heng Yang Medical College, University of South China, Hengyang, 421001, Hunan, China.
Chen X; Clinical Anatomy & Reproductive Medicine Application Institute, Heng Yang Medical College, University of South China, Hengyang, 421001, Hunan, China.
Tang ZH; Postdoctoral Station for Basic Medicine, Hengyang Medical College, University of South China, Hengyang, 421001, Hunan, China. .
Hu LL; China Reproductive Medicine Center, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000, Guangxi, China. .
Lei XC; Clinical Anatomy & Reproductive Medicine Application Institute, Heng Yang Medical College, University of South China, Hengyang, 421001, Hunan, China. .; Postdoctoral Station for Basic Medicine, Hengyang Medical College, University of South China, Hengyang, 421001, Hunan, China. .
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Źródło :
Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2022 Mar 07; Vol. 20 (1), pp. 45. Date of Electronic Publication: 2022 Mar 07.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Experimental*/chemically induced
Diabetes Mellitus, Experimental*/complications
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/metabolism
Infertility, Male*/drug therapy
Infertility, Male*/etiology
Infertility, Male*/metabolism
Glycolysis/*drug effects
Spermatogenesis/*drug effects
Spermidine/*pharmacology
Animals ; Diabetes Complications/drug therapy ; Diabetes Complications/metabolism ; Diabetes Complications/pathology ; Diabetes Complications/physiopathology ; Male ; Mice ; Mice, Inbred C57BL ; Semen Analysis ; Spermatogenesis/physiology ; Spermidine/therapeutic use ; Streptozocin ; Testis/drug effects ; Testis/metabolism
Czasopismo naukowe
Tytuł :
Role of heme oxygenase in the regulation of the renal hemodynamics in a model of sex-dependent programmed hypertension by maternal diabetes.
Autorzy :
Martínez-Gascón LE; Servicio de Análisis Clínicos, Hospital General Universitario Santa Lucía, Cartagena, Murcia, Spain.; Instituto Murciano de Investigaciòn Biomédica, IMIB, Murcia, Spain.
Ortiz MC; Departamento de Fisiología, Campus de Excelencia Internacional Regional 'Campus Mare Nostrum', Universidad de Murcia, Murcia, Spain.; Instituto Murciano de Investigaciòn Biomédica, IMIB, Murcia, Spain.
Galindo M; Servicio de Medicina Intensiva, Hospital General Universitario Santa Lucía, Cartagena, Murcia, Spain.; Instituto Murciano de Investigaciòn Biomédica, IMIB, Murcia, Spain.
Sanchez JM; Instituto Murciano de Investigaciòn Biomédica, IMIB, Murcia, Spain.
Sancho-Rodríguez N; Instituto Murciano de Investigaciòn Biomédica, IMIB, Murcia, Spain.
Albaladejo-Otón MD; Servicio de Análisis Clínicos, Hospital General Universitario Santa Lucía, Cartagena, Murcia, Spain.; Instituto Murciano de Investigaciòn Biomédica, IMIB, Murcia, Spain.
Rodríguez Mulero MD; Servicio de Medicina Intensiva, Hospital General Universitario Santa Lucía, Cartagena, Murcia, Spain.; Instituto Murciano de Investigaciòn Biomédica, IMIB, Murcia, Spain.
Rodriguez F; Departamento de Fisiología, Campus de Excelencia Internacional Regional 'Campus Mare Nostrum', Universidad de Murcia, Murcia, Spain.; Instituto Murciano de Investigaciòn Biomédica, IMIB, Murcia, Spain.
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Źródło :
American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2022 Mar 01; Vol. 322 (3), pp. R181-R191. Date of Electronic Publication: 2022 Jan 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes, Gestational*/enzymology
Diabetes, Gestational*/physiopathology
Hemodynamics*
Prenatal Exposure Delayed Effects*
Renal Circulation*
Diabetes Mellitus, Experimental/*complications
Heme Oxygenase (Decyclizing)/*metabolism
Hypertension/*etiology
Kidney/*blood supply
Animals ; Diabetes Mellitus, Experimental/enzymology ; Diabetes Mellitus, Experimental/physiopathology ; Female ; Hypertension/enzymology ; Hypertension/physiopathology ; Kidney/enzymology ; Male ; Oxidative Stress ; Pregnancy ; Rats, Sprague-Dawley ; Sex Factors
Czasopismo naukowe
Tytuł :
Long-term GABA administration improves FNDC5, TFAM, and UCP3 mRNA expressions in the skeletal muscle and serum irisin levels in chronic type 2 diabetic rats.
Autorzy :
Yazdanimoghaddam F; Department of Clinical Biochemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
Ghasemi M; Department of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Teamparvar H; School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
Soltani N; Department of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Aghaei M; Department of Clinical Biochemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
Rezazadeh H; Department of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Zadhoush F; Department of Clinical Biochemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran. .
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Źródło :
Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2022 Apr; Vol. 395 (4), pp. 417-428. Date of Electronic Publication: 2022 Feb 02.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/metabolism
Fibronectins*/blood
Transcription Factors*/genetics
Transcription Factors*/metabolism
Uncoupling Protein 3*/genetics
Uncoupling Protein 3*/metabolism
gamma-Aminobutyric Acid*/pharmacology
Animals ; Diabetes Mellitus, Type 2 ; Muscle, Skeletal/metabolism ; RNA, Messenger/metabolism ; Rats
Czasopismo naukowe
Tytuł :
Serum levels of novel anti-inflammatory cytokine Interleukin-38 in diabetes patients infected with latent tuberculosis (DM-LTB-3).
Autorzy :
Aravindhan V; Dept of Genetics, Dr ALM PG IBMS, University of Madras, Taramani, Chennai, India. Electronic address: .
Bobhate A; Prof. M. Viswanathan Diabetes Research Centre, Chennai, India.
Sathishkumar K; Dept of Genetics, Dr ALM PG IBMS, University of Madras, Taramani, Chennai, India.
Viswanathan V; Prof. M. Viswanathan Diabetes Research Centre, Chennai, India. Electronic address: .
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Źródło :
Journal of diabetes and its complications [J Diabetes Complications] 2022 Mar; Vol. 36 (3), pp. 108133. Date of Electronic Publication: 2022 Jan 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cytokines*/blood
Diabetes Mellitus*/blood
Diabetes Mellitus*/immunology
Interleukins*/blood
Interleukins*/immunology
Latent Tuberculosis*/blood
Latent Tuberculosis*/complications
Latent Tuberculosis*/immunology
Diabetes Complications/immunology ; Enzyme-Linked Immunosorbent Assay ; Humans ; Tumor Necrosis Factor-alpha
Czasopismo naukowe
Tytuł :
ChREBPβ is dispensable for the control of glucose homeostasis and energy balance.
Autorzy :
Recazens E; Institute of Metabolic and Cardiovascular Diseases (I2MC), Equipe MetaDiab, University of Toulouse, INSERM, University of Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Tavernier G; Institute of Metabolic and Cardiovascular Diseases (I2MC), Equipe MetaDiab, University of Toulouse, INSERM, University of Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Dufau J; Institute of Metabolic and Cardiovascular Diseases (I2MC), Equipe MetaDiab, University of Toulouse, INSERM, University of Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Bergoglio C; Institute of Metabolic and Cardiovascular Diseases (I2MC), Equipe MetaDiab, University of Toulouse, INSERM, University of Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Benhamed F; University of Paris, Cochin Institute, CNRS, INSERM, Paris, France.
Cassant-Sourdy S; Institute of Metabolic and Cardiovascular Diseases (I2MC), Equipe MetaDiab, University of Toulouse, INSERM, University of Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Marques MA; Institute of Metabolic and Cardiovascular Diseases (I2MC), Equipe MetaDiab, University of Toulouse, INSERM, University of Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Caspar-Bauguil S; Institute of Metabolic and Cardiovascular Diseases (I2MC), Equipe MetaDiab, University of Toulouse, INSERM, University of Toulouse III - Paul Sabatier (UPS), Toulouse, France.; Toulouse University Hospital Center, Biochemisty Laboratory, Toulouse, France.
Brion A; Genome Structure and Instability Laboratory, INSERM, CNRS, National Museum of Natural History, Paris, France.
Monbrun L; Institute of Metabolic and Cardiovascular Diseases (I2MC), Equipe MetaDiab, University of Toulouse, INSERM, University of Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Dentin R; University of Paris, Cochin Institute, CNRS, INSERM, Paris, France.
Ferrier C; Institute of Metabolic and Cardiovascular Diseases (I2MC), Equipe MetaDiab, University of Toulouse, INSERM, University of Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Leroux M; Institute of Metabolic and Cardiovascular Diseases (I2MC), Equipe MetaDiab, University of Toulouse, INSERM, University of Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Denechaud PD; Institute of Metabolic and Cardiovascular Diseases (I2MC), Equipe MetaDiab, University of Toulouse, INSERM, University of Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Moro C; Institute of Metabolic and Cardiovascular Diseases (I2MC), Equipe MetaDiab, University of Toulouse, INSERM, University of Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Concordet JP; Genome Structure and Instability Laboratory, INSERM, CNRS, National Museum of Natural History, Paris, France.
Postic C; University of Paris, Cochin Institute, CNRS, INSERM, Paris, France.
Mouisel E; Institute of Metabolic and Cardiovascular Diseases (I2MC), Equipe MetaDiab, University of Toulouse, INSERM, University of Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Langin D; Institute of Metabolic and Cardiovascular Diseases (I2MC), Equipe MetaDiab, University of Toulouse, INSERM, University of Toulouse III - Paul Sabatier (UPS), Toulouse, France.; Toulouse University Hospital Center, Biochemisty Laboratory, Toulouse, France.; Academic Institute of France (IUF), Paris, France.
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Źródło :
JCI insight [JCI Insight] 2022 Feb 22; Vol. 7 (4). Date of Electronic Publication: 2022 Feb 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Experimental*
Gene Expression Regulation*
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/*genetics
Blood Glucose/*metabolism
Diabetes Mellitus, Type 2/*genetics
Energy Metabolism/*genetics
RNA/*genetics
Animals ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/biosynthesis ; Cells, Cultured ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/pathology ; Female ; Male ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
The RAGE/DIAPH1 Signaling Axis & Implications for the Pathogenesis of Diabetic Complications.
Autorzy :
Ramasamy R; Diabetes Research Program, Department of Medicine, New York University Grossman School of Medicine, New York, NY 10016, USA.
Shekhtman A; Department of Chemistry, The State University of New York at Albany, Albany, NY 12222, USA.
Schmidt AM; Diabetes Research Program, Department of Medicine, New York University Grossman School of Medicine, New York, NY 10016, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2022 Apr 21; Vol. 23 (9). Date of Electronic Publication: 2022 Apr 21.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Diabetes Complications*/metabolism
Formins*/metabolism
Receptor for Advanced Glycation End Products*/metabolism
Carrier Proteins/metabolism ; Diabetes Mellitus, Type 2/complications ; Glycation End Products, Advanced/metabolism ; Humans ; Ligands ; Signal Transduction
Czasopismo naukowe
Tytuł :
An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function.
Autorzy :
Cujba AM; Centre for Stem Cells and Regenerative Medicine, King's College London, London, UK.
Alvarez-Fallas ME; Centre for Stem Cells and Regenerative Medicine, King's College London, London, UK.
Pedraza-Arevalo S; Centre for Stem Cells and Regenerative Medicine, King's College London, London, UK.
Laddach A; Francis Crick Institute, London, UK.
Shepherd MH; University of Exeter Medical School, Exeter, UK.
Hattersley AT; University of Exeter Medical School, Exeter, UK.
Watt FM; Centre for Stem Cells and Regenerative Medicine, King's College London, London, UK.
Sancho R; Centre for Stem Cells and Regenerative Medicine, King's College London, London, UK; Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany. Electronic address: .
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Źródło :
Cell reports [Cell Rep] 2022 Mar 01; Vol. 38 (9), pp. 110425.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus*
Induced Pluripotent Stem Cells*
Hepatocyte Nuclear Factor 1-alpha/*genetics
Cell Differentiation ; Diabetes Mellitus, Type 2 ; Humans ; Pancreas
SCR Disease Name :
Mason-Type Diabetes; Maturity-Onset Diabetes of the Young, Type 3
Czasopismo naukowe
Tytuł :
Association of Fasting Proinsulin Levels with Glycemic Profile in Indian Type 2 Diabetes Patients.
Autorzy :
Aggarwal A; Lady Hardinge Medical College, New Delhi.
Chaudhury D; Lady Hardinge Medical College, New Delhi.
Singh R; Lady Hardinge Medical College, New Delhi.
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Źródło :
The Journal of the Association of Physicians of India [J Assoc Physicians India] 2022 Apr; Vol. 70 (4), pp. 11-12.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Diabetes Mellitus, Type 2*
Proinsulin*/metabolism
Adult ; Aged ; Aged, 80 and over ; Blood Glucose/metabolism ; Cross-Sectional Studies ; Diabetes Mellitus ; Fasting ; Glucose Tolerance Test ; Glycated Hemoglobin A ; Humans ; Insulin ; Middle Aged ; Triglycerides
SCR Disease Name :
Hyperproinsulinemia
Czasopismo naukowe
Tytuł :
Can Overnutrition Lead to Wasting?-The Paradox of Diabetes Mellitus in End-Stage Renal Disease Treated with Maintenance Hemodialysis.
Autorzy :
Hoppe K; Department of Nephrology, Transplantology and Internal Diseases, Poznan University of Medical Sciences, 60-355 Poznań, Poland.
Schwermer K; Department of Nephrology, Transplantology and Internal Diseases, Poznan University of Medical Sciences, 60-355 Poznań, Poland.
Dopierała M; Department of Nephrology, Transplantology and Internal Diseases, Poznan University of Medical Sciences, 60-355 Poznań, Poland.
Kałużna M; Department of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, 60-355 Poznań, Poland.
Hoppe A; Department of Haematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, 60-569 Poznań, Poland.
Chou JT; Department of Nephrology, Transplantology and Internal Diseases, Poznan University of Medical Sciences, 60-355 Poznań, Poland.
Oko A; Department of Nephrology, Transplantology and Internal Diseases, Poznan University of Medical Sciences, 60-355 Poznań, Poland.
Pawlaczyk K; Department of Nephrology, Transplantology and Internal Diseases, Poznan University of Medical Sciences, 60-355 Poznań, Poland.
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Źródło :
Nutrients [Nutrients] 2022 Jan 07; Vol. 14 (2). Date of Electronic Publication: 2022 Jan 07.
Typ publikacji :
Journal Article; Multicenter Study; Observational Study
MeSH Terms :
Diabetes Mellitus*/blood
Renal Dialysis*
Diabetes Complications/*complications
Kidney Failure, Chronic/*therapy
Overnutrition/*complications
Protein-Energy Malnutrition/*etiology
Adipose Tissue ; Aged ; Biomarkers/blood ; Body Composition ; Body Mass Index ; Cardiovascular Diseases/mortality ; Cause of Death ; Cholesterol/blood ; Comorbidity ; Creatinine/blood ; Diabetes Complications/blood ; Diabetes Complications/mortality ; Diagnostic Self Evaluation ; Diet ; Electric Impedance ; Female ; Humans ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/mortality ; Male ; Middle Aged ; Prospective Studies ; Serum Albumin/analysis
Czasopismo naukowe
Tytuł :
ChREBP deficiency alleviates apoptosis by inhibiting TXNIP/oxidative stress in diabetic nephropathy.
Autorzy :
Chen N; Department of Pathology, Hebei Medical University, Shijiazhuang, China; Department of Pathology, Medical School, Hebei University of Engineering, Handan, China.
Song S; Department of Pathology, Hebei Medical University, Shijiazhuang, China; Hebei Key Laboratory of Kidney Disease, Shijiazhuang, China.
Yang Z; Department of Pathology, Hebei Medical University, Shijiazhuang, China. Electronic address: .
Wu M; Department of Pathology, Hebei Medical University, Shijiazhuang, China.
Mu L; Department of Pathology, Hebei Medical University, Shijiazhuang, China; Hebei Key Laboratory of Kidney Disease, Shijiazhuang, China; Department of Nephrology, Second Hospital, Hebei Medical University, Shijiazhuang, China.
Zhou T; Department of Pathology, Hebei Medical University, Shijiazhuang, China.
Shi Y; Department of Pathology, Hebei Medical University, Shijiazhuang, China; Hebei Key Laboratory of Kidney Disease, Shijiazhuang, China. Electronic address: .
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Źródło :
Journal of diabetes and its complications [J Diabetes Complications] 2021 Dec; Vol. 35 (12), pp. 108050. Date of Electronic Publication: 2021 Sep 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors*/biosynthesis
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors*/deficiency
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors*/genetics
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors*/metabolism
Carrier Proteins*/biosynthesis
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/metabolism
Diabetic Nephropathies*/etiology
Diabetic Nephropathies*/genetics
Diabetic Nephropathies*/metabolism
Thioredoxins*/biosynthesis
Animals ; Apoptosis/physiology ; Blood Glucose/analysis ; Cells, Cultured ; Diabetes Mellitus, Experimental/chemically induced ; Diabetes Mellitus, Experimental/genetics ; Diabetes Mellitus, Experimental/metabolism ; Disease Models, Animal ; Endoplasmic Reticulum Stress/physiology ; Gene Editing ; Humans ; Hyperglycemia/complications ; Hyperglycemia/metabolism ; Kidney/cytology ; Kidney/metabolism ; Kidney/pathology ; Mice ; Mice, Inbred C57BL ; Oxidative Stress/physiology
Czasopismo naukowe
Tytuł :
Salivary VEGF and post-extraction wound healing in type 2 diabetic immediate denture wearers.
Autorzy :
Radović K; Faculty of Dental Medicine, Department of Prosthetic Dentistry, University of Belgrade, Belgrade, Serbia.
Brković B; Faculty of Dental Medicine, Department of Oral Surgery, University of Belgrade, Belgrade, Serbia.
Roganović J; Faculty of Dental Medicine, Department of Pharmacology in Dentistry, University of Belgrade, Belgrade, Serbia.
Ilić J; Faculty of Dental Medicine, Department of Restorative Odontology and Endodontics, University of Belgrade, Belgrade, Serbia.
Milić Lemić A; Faculty of Dental Medicine, Department of Prosthetic Dentistry, University of Belgrade, Belgrade, Serbia.
Jovanović B; Faculty of Dental Medicine, Department of Prosthetic Dentistry, University of Belgrade, Belgrade, Serbia.
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Źródło :
Acta odontologica Scandinavica [Acta Odontol Scand] 2022 Jan; Vol. 80 (1), pp. 9-14. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article
MeSH Terms :
Dentures*
Diabetes Mellitus, Type 2*/complications
Tooth Extraction*
Vascular Endothelial Growth Factor A*
Wound Healing*
Animals ; Diabetes Mellitus, Experimental ; Humans ; Rats ; Saliva
Czasopismo naukowe
Tytuł :
Cyperus iria aqueous-ethanol extract ameliorated hyperglycemia, oxidative stress, and regulated inflammatory cytokines in streptozotocin-induced diabetic rats.
Autorzy :
Saeed M; Faculty of Pharmacy, Faculty of Allied Healh and Sciences, The University of Lahore, Lahore, Pakistan.
Sharif A; Institute of Pharmacy, Faculty of Pharmaceutical and Allied Health Sciences, Lahore College for Women University, Lahore, Pakistan. .
Hassan SU; Imran Idress College of Pharmacy, 3-km Daska Road, Sialkot, Pakistan.
Akhtar B; Department of Pharmacy, University of Agriculture, Faisalabad, Pakistan.
Muhammad F; Institute of Physiology and Pharmacology, University of Agriculture, Faisalabad, Pakistan.
Malik M; Faculty of Pharmacy, The University of Lahore, Lahore, Pakistan.
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Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2022 Jan; Vol. 29 (3), pp. 4769-4784. Date of Electronic Publication: 2021 Aug 20.
Typ publikacji :
Journal Article
MeSH Terms :
Cyperus*/chemistry
Diabetes Mellitus, Experimental*/drug therapy
Hyperglycemia*/drug therapy
Oxidative Stress*/drug effects
Plant Extracts/*pharmacology
Animals ; Blood Glucose ; Cytokines ; Diabetes Mellitus, Type 2/drug therapy ; Ethanol ; Rats ; Streptozocin
Czasopismo naukowe
Tytuł :
Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases.
Autorzy :
Cefalu WT; 1Division of Diabetes, Endocrinology and Metabolic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
Andersen DK; 2Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
Arreaza-Rubín G; 1Division of Diabetes, Endocrinology and Metabolic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
Pin CL; 3Departments of Physiology and Pharmacology, Paediatrics, and Oncology, University of Western Ontario, and Genetics and Development Division, Children's Health Research Institute, Lawson Health Research Institute, London, Ontario, Canada.
Sato S; 1Division of Diabetes, Endocrinology and Metabolic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
Verchere CB; 4Departments of Surgery and Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; 5BC Children's Hospital, Vancouver, British Columbia, Canada.; 6UBC Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada.
Woo M; 7Departments of Medicine and Immunology, University of Toronto, Toronto, Ontario, Canada.; 8Division of Endocrinology and Metabolism, University Health Network and Sinai Health System, Toronto, Ontario, Canada.; 9Toronto General Hospital Research Institute, Toronto, Ontario, Canada.
Rosenblum ND; 10Canadian Institutes of Health Research Institute of Nutrition, Metabolism and Diabetes, Toronto, Ontario, Canada.; 11Division of Nephrology, Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada.; 12Program in Stem Cell and Developmental Biology, Research Institute, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada.
Rosenblum N
Cefalu W
Andersen DK
Arreaza-Rubín G
Dhara C
James SP
Makarchuk MJ
Pin CL
Sato S
Verchere B
Woo M
Powers A
Estall J
Hoesli C
Millman J
Linnemann A
Johnson J
Pin CL
Hawkins M
Woo M
Gloyn A
Cefalu W
Rosenblum N
Huising MO
Benninger RKP
Almaça J
Hull-Meichle RL
MacDonald P
Lynn F
Melero-Martin J
Yoshihara E
Stabler C
Sander M
Evans-Molina C
Engin F
Thompson P
Shalev A
Redondo MJ
Nadeau K
Bellin M
Udler MS
Dennis J
Dash S
Zhou W
Snyder M
Booth G
Butte A
Florez J
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Corporate Authors :
Symposium planning committee, moderators, and speakers:
Źródło :
Diabetes care [Diabetes Care] 2022 Jan 01; Vol. 45 (1), pp. 3-22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Diabetes Mellitus*/therapy
Precision Medicine*
Canada ; Humans ; National Institute of Diabetes and Digestive and Kidney Diseases (U.S.) ; National Institutes of Health (U.S.) ; Phenotype ; United States
Czasopismo naukowe
Tytuł :
Effect of 1-Deoxynojirimycin on insulin resistance in prediabetic mice based on next-generation sequencing and intestinal microbiota study.
Autorzy :
Ren X; School of Bioengineering, Dalian University of Technology, Dalian, Liaoning, 116024, China. Electronic address: .
Xing Y; School of Bioengineering, Dalian University of Technology, Dalian, Liaoning, 116024, China. Electronic address: .
He L; School of Bioengineering, Dalian University of Technology, Dalian, Liaoning, 116024, China. Electronic address: .
Xiu Z; School of Bioengineering, Dalian University of Technology, Dalian, Liaoning, 116024, China. Electronic address: .
Yang L; Xinjiang Production and Construction Corps Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin, Tarim University, Alar, Xinjiang, 843300, China; Instrumental Analysis Center, Tarim University, Alar, Xinjiang, 843300, China. Electronic address: .
Han A; Instrumental Analysis Center, Tarim University, Alar, Xinjiang, 843300, China. Electronic address: .
Jia Q; Instrumental Analysis Center, Tarim University, Alar, Xinjiang, 843300, China. Electronic address: .
Dong Y; School of Bioengineering, Dalian University of Technology, Dalian, Liaoning, 116024, China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2022 May 10; Vol. 289, pp. 115029. Date of Electronic Publication: 2022 Jan 22.
Typ publikacji :
Journal Article
MeSH Terms :
1-Deoxynojirimycin/*pharmacology
Diabetes Mellitus, Experimental/*drug therapy
Gastrointestinal Microbiome/*drug effects
Prediabetic State/*drug therapy
1-Deoxynojirimycin/isolation & purification ; Animals ; Blood Glucose/drug effects ; Diabetes Mellitus, Type 2/prevention & control ; Disease Progression ; High-Throughput Nucleotide Sequencing ; Insulin Resistance ; Lipid Metabolism/drug effects ; Male ; Mice ; Mice, Inbred C57BL ; Morus/chemistry ; Streptozocin
Czasopismo naukowe
Tytuł :
Blood pressure in children with renal cysts and diabetes syndrome.
Autorzy :
Seeman T; Department of Pediatrics, 2nd Faculty of Medicine, Charles University Prague, Prague, Czech Republic. .; Department of Pediatrics, Dr. von Hauner Children´s Hospital, University Hospital, LMU Munich, Munich, Germany. .
Weigel F; Department of Pediatrics, Friedrich-Schiller-University Jena, Jena, Germany.
Blahova K; Department of Pediatrics, 2nd Faculty of Medicine, Charles University Prague, Prague, Czech Republic.
Fencl F; Department of Pediatrics, 2nd Faculty of Medicine, Charles University Prague, Prague, Czech Republic.
Pruhova S; Department of Pediatrics, 2nd Faculty of Medicine, Charles University Prague, Prague, Czech Republic.
Hermes K; Department of Pediatrics, Dr. von Hauner Children´s Hospital, University Hospital, LMU Munich, Munich, Germany.
Klaus R; Department of Pediatrics, Dr. von Hauner Children´s Hospital, University Hospital, LMU Munich, Munich, Germany.
Lange-Sperandio B; Department of Pediatrics, Dr. von Hauner Children´s Hospital, University Hospital, LMU Munich, Munich, Germany.
Grote V; Department of Pediatrics, Dr. von Hauner Children´s Hospital, University Hospital, LMU Munich, Munich, Germany.
John-Kroegel U; Department of Pediatrics, Friedrich-Schiller-University Jena, Jena, Germany.
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Źródło :
European journal of pediatrics [Eur J Pediatr] 2021 Dec; Vol. 180 (12), pp. 3599-3603. Date of Electronic Publication: 2021 Jun 26.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus*
Hypertension*/epidemiology
Hypertension*/etiology
Polycystic Kidney, Autosomal Dominant*
Blood Pressure ; Blood Pressure Monitoring, Ambulatory ; Central Nervous System Diseases ; Child ; Dental Enamel/abnormalities ; Diabetes Mellitus, Type 2 ; Humans ; Kidney Diseases, Cystic ; Retrospective Studies
SCR Disease Name :
Renal cysts and diabetes syndrome
Czasopismo naukowe

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