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Wyszukujesz frazę ""differentiation"" wg kryterium: Temat


Tytuł :
CD226 and TIGIT Cooperate in the Differentiation and Maturation of Human Tfh Cells.
Autorzy :
Yasutomi M; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Christiaansen AF; EMD Serono Research and Development Institute Inc. (The Healthcare Business of Merck KGaA, Darmstadt, Germany), Billerica, MA, United States.
Imai N; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Martin-Orozco N; EMD Serono Research and Development Institute Inc. (The Healthcare Business of Merck KGaA, Darmstadt, Germany), Billerica, MA, United States.
Forst CV; Department of Genetics and Genomic Sciences, Department of Microbiology, The Icahn Institute for Data Science and Genomic Technology, New York, NY, United States.
Chen G; EMD Serono Research and Development Institute Inc. (The Healthcare Business of Merck KGaA, Darmstadt, Germany), Billerica, MA, United States.
Ueno H; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; ASHBi Institute for the Advanced Study of Human Biology, Kyoto University, Kyoto, Japan.
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Źródło :
Frontiers in immunology [Front Immunol] 2022 Feb 22; Vol. 13, pp. 840457. Date of Electronic Publication: 2022 Feb 22 (Print Publication: 2022).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, Differentiation, T-Lymphocyte*/metabolism
Receptors, Immunologic*/metabolism
T Follicular Helper Cells*
Cell Differentiation ; Humans ; Lymphocyte Activation ; T-Lymphocyte Subsets
Czasopismo naukowe
Tytuł :
Hyaline cartilage differentiation of fibroblasts in regeneration and regenerative medicine.
Autorzy :
Yu L; Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Lin YL; Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Yan M; Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Li T; Department of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, People's Republic of China.
Wu EY; Dewpoint Therapeutics, 6 Tide Street, Suite 300, Boston, MA 02210, USA.
Zimmel K; Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Qureshi O; Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Falck A; Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Sherman KM; Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Huggins SS; Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Hurtado DO; Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Suva LJ; Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Gaddy D; Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Cai J; Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Brunauer R; Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Dawson LA; Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Muneoka K; Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
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Źródło :
Development (Cambridge, England) [Development] 2022 Jan 15; Vol. 149 (2). Date of Electronic Publication: 2022 Jan 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cell Differentiation*
Regeneration*
Fibroblasts/*cytology
Hyaline Cartilage/*cytology
Tissue Engineering/*methods
Animals ; Cells, Cultured ; Chondrocytes/cytology ; Chondrocytes/drug effects ; Chondrogenesis ; Fibroblasts/drug effects ; Growth Differentiation Factor 2/pharmacology ; Hyaline Cartilage/metabolism ; Hyaline Cartilage/physiology ; Mice ; Mice, Inbred C57BL ; Mice, Inbred NOD ; Mice, SCID
Czasopismo naukowe
Tytuł :
Identification of liver-derived bone morphogenetic protein (BMP)-9 as a potential new candidate for treatment of colorectal cancer.
Autorzy :
Cai C; Department of Medicine II, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Itzel T; Department of Medicine II, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Gaitantzi H; Department of Medicine II, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
de la Torre C; Medical Research Center, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Birgin E; Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Betge J; Department of Medicine II, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Gretz N; Medical Research Center, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Teufel A; Department of Medicine II, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Rahbari NN; Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Ebert MP; Department of Medicine II, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Breitkopf-Heinlein K; Department of Medicine II, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2022 Jan; Vol. 26 (2), pp. 343-353. Date of Electronic Publication: 2021 Nov 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Colonic Neoplasms*
Colorectal Neoplasms*/genetics
Growth Differentiation Factor 2*/genetics
Bone Morphogenetic Protein 2 ; Bone Morphogenetic Protein 4/pharmacology ; Bone Morphogenetic Proteins/genetics ; Bone Morphogenetic Proteins/metabolism ; Humans ; Inhibitor of Differentiation Protein 1 ; Liver/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Mesenchymal stem cells overexpressing BMP-9 by CRISPR-Cas9 present high in vitro osteogenic potential and enhance in vivo bone formation.
Autorzy :
Freitas GP; Bone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
Lopes HB; Bone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
Souza ATP; Bone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
Gomes MPO; Bone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
Quiles GK; Bone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
Gordon J; Department of Biochemistry, University of Vermont School of Medicine, Burlington, VT, USA.
Tye C; Department of Biochemistry, University of Vermont School of Medicine, Burlington, VT, USA.
Stein JL; Department of Biochemistry, University of Vermont School of Medicine, Burlington, VT, USA.
Stein GS; Department of Biochemistry, University of Vermont School of Medicine, Burlington, VT, USA.
Lian JB; Department of Biochemistry, University of Vermont School of Medicine, Burlington, VT, USA.
Beloti MM; Bone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
Rosa AL; Bone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil. .
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Źródło :
Gene therapy [Gene Ther] 2021 Dec; Vol. 28 (12), pp. 748-759. Date of Electronic Publication: 2021 Mar 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Growth Differentiation Factor 2*/genetics
Mesenchymal Stem Cells*/cytology
Osteogenesis*/genetics
Animals ; CRISPR-Cas Systems ; Cell Differentiation ; Cells, Cultured ; Rats
Czasopismo naukowe
Tytuł :
Hop2 interacts with the transcription factor CEBPα and suppresses adipocyte differentiation.
Autorzy :
Lin T; Department of Pediatrics, Pediatric Research Center, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas, USA.
Zhang Y; Department of Pediatrics, Pediatric Research Center, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas, USA.
Zhang T; Department of Pediatrics, Pediatric Research Center, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas, USA.
Steckler RA; Department of Pediatrics, Pediatric Research Center, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas, USA.
Yang X; Department of Pediatrics, Pediatric Research Center, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas, USA. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2021 Nov; Vol. 297 (5), pp. 101264. Date of Electronic Publication: 2021 Sep 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipogenesis*
Cell Differentiation*
Gene Expression Regulation*
Adipocytes/*metabolism
CCAAT-Enhancer-Binding Proteins/*metabolism
Cell Cycle Proteins/*metabolism
3T3 Cells ; Animals ; Antigens, Differentiation/biosynthesis ; Antigens, Differentiation/genetics ; CCAAT-Enhancer-Binding Proteins/genetics ; Cell Cycle Proteins/genetics ; Mice ; Mice, Knockout
Czasopismo naukowe
Tytuł :
MyD88-dependent TLR signaling oppositely regulates hematopoietic progenitor and stem cell formation in the embryo.
Autorzy :
Bennett LF; Abramson Family Cancer Research Institute and Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Mumau MD; Abramson Family Cancer Research Institute and Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Li Y; Department of Veterinary Medicine and Institute of Preventive Veterinary Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, People's Republic of China.
Speck NA; Abramson Family Cancer Research Institute and Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
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Źródło :
Development (Cambridge, England) [Development] 2022 Apr 15; Vol. 149 (8). Date of Electronic Publication: 2022 Feb 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Signal Transduction*
Embryo, Mammalian/*metabolism
Hematopoietic Stem Cells/*metabolism
Myeloid Differentiation Factor 88/*metabolism
Animals ; Cell Differentiation ; Core Binding Factor Alpha 2 Subunit/metabolism ; Embryo, Mammalian/cytology ; Endothelial Cells/cytology ; Endothelial Cells/metabolism ; Hemangioblasts/cytology ; Hemangioblasts/metabolism ; Hematopoietic Stem Cells/cytology ; Immunity, Innate ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Myeloid Cells/cytology ; Myeloid Cells/metabolism ; Myeloid Differentiation Factor 88/deficiency ; Myeloid Differentiation Factor 88/genetics ; Toll-Like Receptor 4/deficiency ; Toll-Like Receptor 4/genetics ; Toll-Like Receptor 4/metabolism ; Toll-Like Receptors/metabolism
Czasopismo naukowe
Tytuł :
MicroRNA-24-3p promotes skeletal muscle differentiation and regeneration by regulating HMGA1.
Autorzy :
Dey P; The RNA Institute, University at Albany, State University of New York (SUNY), 1400 Washington Avenue, Albany, NY, 12222, USA.
Soyer MA; The RNA Institute, University at Albany, State University of New York (SUNY), 1400 Washington Avenue, Albany, NY, 12222, USA.; Department of Biological Sciences, University at Albany, State University of New York (SUNY), 1400 Washington Avenue, Albany, NY, 12222, USA.
Dey BK; The RNA Institute, University at Albany, State University of New York (SUNY), 1400 Washington Avenue, Albany, NY, 12222, USA. .; Department of Biological Sciences, University at Albany, State University of New York (SUNY), 1400 Washington Avenue, Albany, NY, 12222, USA. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2022 Mar 03; Vol. 79 (3), pp. 170. Date of Electronic Publication: 2022 Mar 03.
Typ publikacji :
Journal Article
MeSH Terms :
HMGA1a Protein/*metabolism
Inhibitor of Differentiation Proteins/*metabolism
MicroRNAs/*metabolism
Muscle, Skeletal/*metabolism
Animals ; Cell Differentiation ; Cell Line ; Cell Proliferation ; Mice ; Muscle Development ; Muscle, Skeletal/cytology ; Myoblasts
Czasopismo naukowe
Tytuł :
Cyclic Polypeptide D7 Protects Bone Marrow Mesenchymal Cells and Promotes Chondrogenesis during Osteonecrosis of the Femoral Head via Growth Differentiation Factor 15-Mediated Redox Signaling.
Autorzy :
Chen J; Department of Joint Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
Cui Z; Department of Joint Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China.; Orthopaedic Research Laboratory, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China.
Wang Y; Department of Joint Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
Lyu L; Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, China.
Feng C; Department of Joint Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China.; Orthopaedic Research Laboratory, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China.
Feng D; Department of Joint Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
Cheng Y; Department of Joint Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
Li Z; Department of Joint Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China.; Orthopaedic Research Laboratory, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China.
Sun S; Department of Joint Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.; Department of Joint Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China.; Orthopaedic Research Laboratory, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China.
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Źródło :
Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2022 Mar 03; Vol. 2022, pp. 3182368. Date of Electronic Publication: 2022 Mar 03 (Print Publication: 2022).
Typ publikacji :
Journal Article
MeSH Terms :
Bone Marrow/*metabolism
Chondrogenesis/*genetics
Femur Head/*physiopathology
Growth Differentiation Factor 15/*metabolism
Mesenchymal Stem Cells/*metabolism
Osteonecrosis/*genetics
Animals ; Cell Differentiation ; Humans ; Osteonecrosis/pathology ; Oxidation-Reduction ; Rats ; Rats, Sprague-Dawley ; Signal Transduction
Czasopismo naukowe
Tytuł :
E-Protein Inhibition in ILC2 Development Shapes the Function of Mature ILC2s during Allergic Airway Inflammation.
Autorzy :
Barshad G; Baker Institute for Animal Health, Cornell University College of Veterinary Medicine, Ithaca, NY.; Department of Biomedical Sciences, Cornell University College of Veterinary Medicine, Ithaca, NY.
Webb LM; Department of Immunology, University of Washington, Seattle, WA; .
Ting HA; Department of Immunology, University of Washington, Seattle, WA.
Oyesola OO; Department of Immunology, University of Washington, Seattle, WA.
Onyekwere OG; Baker Institute for Animal Health, Cornell University College of Veterinary Medicine, Ithaca, NY.; Department of Microbiology and Immunology, Cornell University College of Veterinary Medicine, Ithaca, NY; and.
Lewis JJ; Baker Institute for Animal Health, Cornell University College of Veterinary Medicine, Ithaca, NY.; Department of Biomedical Sciences, Cornell University College of Veterinary Medicine, Ithaca, NY.
Rice EJ; Baker Institute for Animal Health, Cornell University College of Veterinary Medicine, Ithaca, NY.; Department of Biomedical Sciences, Cornell University College of Veterinary Medicine, Ithaca, NY.
Matheson MK; Department of Immunology, University of Washington, Seattle, WA.
Sun XH; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK.
von Moltke J; Department of Immunology, University of Washington, Seattle, WA.
Danko CG; Baker Institute for Animal Health, Cornell University College of Veterinary Medicine, Ithaca, NY.; Department of Biomedical Sciences, Cornell University College of Veterinary Medicine, Ithaca, NY.
Tait Wojno ED; Department of Immunology, University of Washington, Seattle, WA; .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2022 Mar 01; Vol. 208 (5), pp. 1007-1020. Date of Electronic Publication: 2022 Feb 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, Dermatophagoides/*immunology
Asthma/*immunology
Inhibitor of Differentiation Protein 1/*metabolism
T-Lymphocytes/*immunology
Transcription Factors/*metabolism
Adaptor Proteins, Signal Transducing/genetics ; Allergens/immunology ; Animals ; Asthma/pathology ; Cell Differentiation/immunology ; Chromatin/metabolism ; Cytokines/immunology ; DNA-Binding Proteins/antagonists & inhibitors ; Female ; Lectins, C-Type/genetics ; Lung/immunology ; Lung/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Pyroglyphidae/immunology ; Receptors, Immunologic/genetics ; Stem Cells/cytology ; T-Lymphocytes/cytology ; Transcription Factor AP-1/metabolism
Czasopismo naukowe
Tytuł :
Bladder tumor ILC1s undergo Th17-like differentiation in human bladder cancer.
Autorzy :
Mukherjee N; Department of Urology, University of Texas Health San Antonio (UTHSA), San Antonio, Texas, USA.
Ji N; Department of Urology, University of Texas Health San Antonio (UTHSA), San Antonio, Texas, USA.
Tan X; Department of Molecular Medicine, University of Texas Health San Antonio (UTHSA), San Antonio, Texas, USA.
Lin CL; Department of Molecular Medicine, University of Texas Health San Antonio (UTHSA), San Antonio, Texas, USA.
Rios E; Department of Urology, University of Texas Health San Antonio (UTHSA), San Antonio, Texas, USA.
Chen CL; Department of Molecular Medicine, University of Texas Health San Antonio (UTHSA), San Antonio, Texas, USA.
Huang T; Department of Molecular Medicine, University of Texas Health San Antonio (UTHSA), San Antonio, Texas, USA.
Svatek RS; Department of Urology, University of Texas Health San Antonio (UTHSA), San Antonio, Texas, USA.
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Źródło :
Cancer medicine [Cancer Med] 2021 Oct; Vol. 10 (20), pp. 7101-7110. Date of Electronic Publication: 2021 Sep 08.
Typ publikacji :
Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Lymphocytes, Tumor-Infiltrating/*cytology
Th17 Cells/*cytology
Urinary Bladder Neoplasms/*pathology
Aged ; Antigens, CD/metabolism ; Antigens, Differentiation, T-Lymphocyte/metabolism ; Female ; Flow Cytometry ; Hepatitis A Virus Cellular Receptor 2/metabolism ; Humans ; Image Cytometry ; Immunity, Cellular ; Interferon-gamma/metabolism ; Interleukin-17/metabolism ; Interleukins/metabolism ; Lectins, C-Type/metabolism ; Lymphocytes, Tumor-Infiltrating/immunology ; Lymphocytes, Tumor-Infiltrating/metabolism ; Male ; Natural Cytotoxicity Triggering Receptor 1/metabolism ; Natural Cytotoxicity Triggering Receptor 3/metabolism ; Neoplasm Invasiveness ; Perforin/metabolism ; Programmed Cell Death 1 Receptor/metabolism ; Th17 Cells/immunology ; Th17 Cells/metabolism ; Urinary Bladder Neoplasms/immunology
Czasopismo naukowe
Tytuł :
Progression and Differentiation of Alveolar Rhabdomyosarcoma Is Regulated by PAX7 Transcription Factor-Significance of Tumor Subclones.
Autorzy :
Skrzypek K; Department of Transplantation, Faculty of Medicine, Institute of Pediatrics, Jagiellonian University Medical College, 30-663 Krakow, Poland.
Adamek G; Department of Transplantation, Faculty of Medicine, Institute of Pediatrics, Jagiellonian University Medical College, 30-663 Krakow, Poland.
Kot M; Department of Transplantation, Faculty of Medicine, Institute of Pediatrics, Jagiellonian University Medical College, 30-663 Krakow, Poland.
Badyra B; Department of Transplantation, Faculty of Medicine, Institute of Pediatrics, Jagiellonian University Medical College, 30-663 Krakow, Poland.
Majka M; Department of Transplantation, Faculty of Medicine, Institute of Pediatrics, Jagiellonian University Medical College, 30-663 Krakow, Poland.
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Źródło :
Cells [Cells] 2021 Jul 23; Vol. 10 (8). Date of Electronic Publication: 2021 Jul 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
PAX7 Transcription Factor/*metabolism
Rhabdomyosarcoma, Alveolar/*metabolism
Animals ; Cell Adhesion Molecules/genetics ; Cell Adhesion Molecules/metabolism ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Disease Progression ; Gene Expression Regulation, Neoplastic ; Humans ; Inhibitor of Differentiation Proteins/genetics ; Inhibitor of Differentiation Proteins/metabolism ; Mice, Inbred NOD ; Mice, SCID ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Neoplasm Invasiveness ; PAX7 Transcription Factor/genetics ; Rhabdomyosarcoma, Alveolar/genetics ; Rhabdomyosarcoma, Alveolar/pathology ; Signal Transduction ; Tumor Burden
Czasopismo naukowe
Tytuł :
Effect of lentivirus-mediated growth and differentiation factor-5 transfection on differentiation of rabbit nucleus pulposus mesenchymal stem cells.
Autorzy :
Zhu K; Department of Orthopaedics, The First Affiliated Hospital of Bengbu Medical College, No. 287, Changhuai Road, Bengbu, 233000, Anhui, China.
Zhao R; Department of General Medicine, Bengbu Medical College, Bengbu, China.
Ye Y; Department of Orthopaedics, The First Affiliated Hospital of Bengbu Medical College, No. 287, Changhuai Road, Bengbu, 233000, Anhui, China.
Xu G; Department of Orthopaedics, The First Affiliated Hospital of Bengbu Medical College, No. 287, Changhuai Road, Bengbu, 233000, Anhui, China. .
Zhang C; Department of Orthopaedics, The First Affiliated Hospital of Bengbu Medical College, No. 287, Changhuai Road, Bengbu, 233000, Anhui, China. .
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Źródło :
European journal of medical research [Eur J Med Res] 2022 Jan 13; Vol. 27 (1), pp. 5. Date of Electronic Publication: 2022 Jan 13.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation*
Lentivirus*
Growth Differentiation Factor 5/*genetics
Lentivirus Infections/*virology
Mesenchymal Stem Cells/*cytology
Nucleus Pulposus/*metabolism
Animals ; Cell Differentiation ; Cells, Cultured ; Disease Models, Animal ; Growth Differentiation Factor 5/biosynthesis ; Lentivirus Infections/metabolism ; Lentivirus Infections/pathology ; Mesenchymal Stem Cells/virology ; Nucleus Pulposus/pathology ; Nucleus Pulposus/virology ; Rabbits
Czasopismo naukowe
Tytuł :
Intracellular density is a novel indicator of differentiation stages of murine osteoblast lineage cells.
Autorzy :
Itoh Y; Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, Osaka, Japan.
Itoh S; Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, Osaka, Japan.
Naruse H; Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, Osaka, Japan.
Kagioka T; Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, Osaka, Japan.
Hue MT; Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, Osaka, Japan.
Abe M; Department of Oral Anatomy and Developmental Biology, Osaka University Graduate School of Dentistry, Osaka, Japan.
Hayashi M; Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, Osaka, Japan.
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Źródło :
Journal of cellular biochemistry [J Cell Biochem] 2021 Dec; Vol. 122 (12), pp. 1805-1816. Date of Electronic Publication: 2021 Aug 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Gene Expression Regulation*
Osteogenesis*
Antigens, Differentiation/*biosynthesis
Osteoblasts/*metabolism
Animals ; Mice ; Osteoblasts/cytology
Czasopismo naukowe
Tytuł :
ASCL1 phosphorylation and ID2 upregulation are roadblocks to glioblastoma stem cell differentiation.
Autorzy :
Azzarelli R; Wellcome - Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. .; Department of Oncology, Hutchison-MRC Centre, Hills Road, Cambridge, CB2 0XZ, UK. .; Department of Biology, Unit of Cell and Developmental Biology, University of Pisa, Pisa, Italy. .
McNally A; Wellcome - Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Oncology, Hutchison-MRC Centre, Hills Road, Cambridge, CB2 0XZ, UK.
Dell'Amico C; Department of Biology, Unit of Cell and Developmental Biology, University of Pisa, Pisa, Italy.
Onorati M; Department of Biology, Unit of Cell and Developmental Biology, University of Pisa, Pisa, Italy.
Simons B; Wellcome - Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK.; Department of Mathematics, University of Cambridge, Cambridge, UK.
Philpott A; Wellcome - Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. .; Department of Oncology, Hutchison-MRC Centre, Hills Road, Cambridge, CB2 0XZ, UK. .
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Źródło :
Scientific reports [Sci Rep] 2022 Feb 11; Vol. 12 (1), pp. 2341. Date of Electronic Publication: 2022 Feb 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Basic Helix-Loop-Helix Transcription Factors/*metabolism
Brain Neoplasms/*metabolism
Brain Neoplasms/*physiopathology
Glioblastoma/*metabolism
Glioblastoma/*physiopathology
Inhibitor of Differentiation Protein 2/*genetics
Neoplastic Stem Cells/*metabolism
Amino Acid Motifs ; Basic Helix-Loop-Helix Transcription Factors/chemistry ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Brain Neoplasms/genetics ; Cell Cycle ; Cell Differentiation ; Gene Expression Regulation, Neoplastic ; Glioblastoma/genetics ; Humans ; Inhibitor of Differentiation Protein 2/metabolism ; Neoplastic Stem Cells/cytology ; Phosphorylation
Czasopismo naukowe
Tytuł :
ID2 controls differentiation of enteroendocrine cells in mouse small intestine.
Autorzy :
Zinina VV; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Ruehle F; Institute of Molecular Biology gGmbH, Mainz, Germany.
Winkler P; MSc Programme in Biomedicine, Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Rebmann L; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.; Faculty Medical and Life Sciences, Hochschule Furtwangen University, Furtwangen, Germany.
Lukas H; Institute of Molecular Biology gGmbH, Mainz, Germany.
Möckel S; Institute of Molecular Biology gGmbH, Mainz, Germany.
Diefenbach A; Laboratory of Innate Immunity, Department of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany.; Berlin Institute of Health (BIH), Berlin, Germany.; Mucosal and Developmental Immunology, Deutsches Rheuma-Forschungszentrum (DRFZ), Berlin, Germany.
Mendez-Lago M; Institute of Molecular Biology gGmbH, Mainz, Germany.
Soshnikova N; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
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Źródło :
Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2022 Feb; Vol. 234 (2), pp. e13773. Date of Electronic Publication: 2022 Jan 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*/genetics
Enteroendocrine Cells*
Transcription Factors*/genetics
Inhibitor of Differentiation Protein 2/*genetics
Animals ; Cell Lineage/genetics ; Intestinal Mucosa ; Intestine, Small/cytology ; Mammals ; Mice
Czasopismo naukowe
Tytuł :
Modulation of CD47-SIRPα innate immune checkpoint axis with Fc-function detuned anti-CD47 therapeutic antibody.
Autorzy :
Narla RK; Bristol Myers Squibb, 10300 Campus Point Drive, Suite 100, San Diego, CA, 92121, USA. .
Modi H; Bristol Myers Squibb, 10300 Campus Point Drive, Suite 100, San Diego, CA, 92121, USA.
Bauer D; Bristol Myers Squibb, 10300 Campus Point Drive, Suite 100, San Diego, CA, 92121, USA.
Abbasian M; Bristol Myers Squibb, 10300 Campus Point Drive, Suite 100, San Diego, CA, 92121, USA.
Leisten J; Bristol Myers Squibb, 10300 Campus Point Drive, Suite 100, San Diego, CA, 92121, USA.
Piccotti JR; Bristol Myers Squibb, 10300 Campus Point Drive, Suite 100, San Diego, CA, 92121, USA.
Kopytek S; Bristol Myers Squibb, 10300 Campus Point Drive, Suite 100, San Diego, CA, 92121, USA.
Eckelman BP; Inhibrx, San Diego, CA, USA.
Deveraux Q; Inhibrx, San Diego, CA, USA.
Timmer J; Inhibrx, San Diego, CA, USA.
Zhu D; Bristol Myers Squibb, 10300 Campus Point Drive, Suite 100, San Diego, CA, 92121, USA.
Wong L; Bristol Myers Squibb, 10300 Campus Point Drive, Suite 100, San Diego, CA, 92121, USA.
Escoubet L; Bristol Myers Squibb, 10300 Campus Point Drive, Suite 100, San Diego, CA, 92121, USA.
Raymon HK; Bristol Myers Squibb, 10300 Campus Point Drive, Suite 100, San Diego, CA, 92121, USA.; Artiva Biotherapeutics, San Diego, CA, USA.
Hariharan K; Bristol Myers Squibb, 10300 Campus Point Drive, Suite 100, San Diego, CA, 92121, USA.
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2022 Feb; Vol. 71 (2), pp. 473-489. Date of Electronic Publication: 2021 Jul 10.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies, Monoclonal/*pharmacology
Antigens, Differentiation/*immunology
CD47 Antigen/*immunology
Immunoglobulin Fc Fragments/*immunology
Leukemia, Promyelocytic, Acute/*drug therapy
Macrophages/*immunology
Receptors, Immunologic/*immunology
Animals ; Antibodies, Monoclonal/immunology ; Antigens, Differentiation/metabolism ; Antineoplastic Agents, Immunological/immunology ; Antineoplastic Agents, Immunological/pharmacology ; Apoptosis ; CD47 Antigen/metabolism ; Cell Differentiation ; Cell Proliferation ; Female ; Humans ; Leukemia, Promyelocytic, Acute/immunology ; Leukemia, Promyelocytic, Acute/metabolism ; Leukemia, Promyelocytic, Acute/pathology ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Phagocytosis ; Prognosis ; Receptors, Immunologic/metabolism ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
A growth factor-expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15.
Autorzy :
Patsalos A; Departments of Medicine and Biological Chemistry, Johns Hopkins University School of Medicine, Institute for Fundamental Biomedical Research, Johns Hopkins All Children's Hospital, St. Petersburg, FL.
Halasz L; Departments of Medicine and Biological Chemistry, Johns Hopkins University School of Medicine, Institute for Fundamental Biomedical Research, Johns Hopkins All Children's Hospital, St. Petersburg, FL.
Medina-Serpas MA; Departments of Medicine and Biological Chemistry, Johns Hopkins University School of Medicine, Institute for Fundamental Biomedical Research, Johns Hopkins All Children's Hospital, St. Petersburg, FL.
Berger WK; Departments of Medicine and Biological Chemistry, Johns Hopkins University School of Medicine, Institute for Fundamental Biomedical Research, Johns Hopkins All Children's Hospital, St. Petersburg, FL.
Daniel B; Departments of Medicine and Biological Chemistry, Johns Hopkins University School of Medicine, Institute for Fundamental Biomedical Research, Johns Hopkins All Children's Hospital, St. Petersburg, FL.
Tzerpos P; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Kiss M; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Nagy G; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Fischer C; Max Delbrück Center for Molecular Medicine, Berlin, Germany.
Simandi Z; Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL.
Varga T; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Nagy L; Departments of Medicine and Biological Chemistry, Johns Hopkins University School of Medicine, Institute for Fundamental Biomedical Research, Johns Hopkins All Children's Hospital, St. Petersburg, FL.; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
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Źródło :
The Journal of experimental medicine [J Exp Med] 2022 Jan 03; Vol. 219 (1). Date of Electronic Publication: 2021 Nov 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Profiling/*methods
Growth Differentiation Factor 15/*genetics
Inflammation/*genetics
Intercellular Signaling Peptides and Proteins/*genetics
Macrophages/*metabolism
Regeneration/*genetics
Animals ; Cell Differentiation/genetics ; Cells, Cultured ; Growth Differentiation Factor 15/metabolism ; Inflammation/metabolism ; Intercellular Signaling Peptides and Proteins/metabolism ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Muscle Cells/metabolism ; Muscles/injuries ; Muscles/metabolism ; Muscles/physiopathology ; Myeloid Cells/metabolism ; RNA-Seq/methods
Czasopismo naukowe
Tytuł :
Prosurvival IL-7-Stimulated Weak Strength of mTORC1-S6K Controls T Cell Memory via Transcriptional FOXO1-TCF1-Id3 and Metabolic AMPKα1-ULK1-ATG7 Pathways.
Autorzy :
Xu A; Cancer Research, Saskatchewan Cancer Agency, Saskatoon, Saskatchewan, Canada.; Division of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Leary SC; Department of Biochemistry, Microbiology and Immunology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Islam MF; Cancer Research, Saskatchewan Cancer Agency, Saskatoon, Saskatchewan, Canada.; Division of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Wu Z; Cancer Research, Saskatchewan Cancer Agency, Saskatoon, Saskatchewan, Canada.; Division of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Bhanumathy KK; Cancer Research, Saskatchewan Cancer Agency, Saskatoon, Saskatchewan, Canada.; Division of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Ara A; Cancer Research, Saskatchewan Cancer Agency, Saskatoon, Saskatchewan, Canada.; Division of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Chibbar R; Department of Pathology and Laboratory Medicine, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada; and.
Fleywald A; Department of Pathology and Laboratory Medicine, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada; and.
Ahmed KA; Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Xiang J; Cancer Research, Saskatchewan Cancer Agency, Saskatoon, Saskatchewan, Canada; .; Division of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2022 Jan 01; Vol. 208 (1), pp. 155-168. Date of Electronic Publication: 2021 Dec 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
AMP-Activated Protein Kinases/*metabolism
Autophagy-Related Protein 7/*metabolism
Autophagy-Related Protein-1 Homolog/*metabolism
CD8-Positive T-Lymphocytes/*immunology
Forkhead Box Protein O1/*metabolism
Hepatocyte Nuclear Factor 1-alpha/*metabolism
Inhibitor of Differentiation Proteins/*metabolism
Interleukin-7/*metabolism
Listeria monocytogenes/*physiology
Listeriosis/*immunology
Mechanistic Target of Rapamycin Complex 1/*metabolism
Memory T Cells/*immunology
Ribosomal Protein S6 Kinases, 90-kDa/*metabolism
AMP-Activated Protein Kinases/genetics ; Animals ; Cell Differentiation ; Cell Survival ; Cells, Cultured ; Cytotoxicity, Immunologic ; Fatty Acids/metabolism ; Forkhead Box Protein O1/genetics ; Gene Expression Regulation ; Glycolysis ; Hepatocyte Nuclear Factor 1-alpha/genetics ; Immunologic Memory ; Inhibitor of Differentiation Proteins/genetics ; Interleukin-7/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, Interleukin-7/genetics ; Signal Transduction ; Vaccine Development
Czasopismo naukowe
Tytuł :
Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma.
Autorzy :
Cheng W; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, 510095, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, 511436, China.
Li HL; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, 510095, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, 511436, China.
Xi SY; State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.
Zhang XF; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, 510095, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, 511436, China.
Zhu Y; Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Le Xing; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, 510095, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, 511436, China.
Mo YX; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, 510095, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, 511436, China.
Li MM; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, 510095, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, 511436, China.
Kong FE; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, 510095, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, 511436, China.
Zhu WJ; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, 510095, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, 511436, China.
Chen XG; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, 510095, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, 511436, China.
Cui HQ; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, 510095, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, 511436, China.
Cao ZM; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, 510095, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, 511436, China.
Gong YF; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, 510095, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, 511436, China.
Tang YQ; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, 510095, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, 511436, China.
Zhang Y; Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Guan XY; Department of Clinical Oncology, State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong, China.
Ma NF; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, 510095, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, 511436, China.
Liu M; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, 510095, China. .; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, 511436, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Dec 08; Vol. 12 (1), pp. 7142. Date of Electronic Publication: 2021 Dec 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunotherapy*
Carcinoma, Hepatocellular/*metabolism
Carcinoma, Hepatocellular/*therapy
Cell Plasticity/*drug effects
Growth Differentiation Factor 1/*metabolism
Growth Differentiation Factor 1/*pharmacology
Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/pathology ; Cell Differentiation ; Cell Line, Tumor ; Cell Proliferation ; Humans ; Liver Neoplasms/metabolism ; Male ; Signal Transduction ; Smad2 Protein/metabolism ; Smad3 Protein/metabolism ; Testicular Neoplasms/metabolism
Czasopismo naukowe
Tytuł :
Effect of interleukin-1β on bone morphogenetic protein-9-induced osteoblastic differentiation of human periodontal ligament fibroblasts.
Autorzy :
Ebe Y; Division of Clinical Engineering, Department of Dental Hygiene, Kagoshima University Hospital, Kagoshima, Japan.
Nakamura T; Department of Periodontology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Hasegawa-Nakamura K; Department of Periodontology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Noguchi K; Department of Periodontology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
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Źródło :
European journal of oral sciences [Eur J Oral Sci] 2021 Aug; Vol. 129 (4), pp. e12792. Date of Electronic Publication: 2021 May 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Growth Differentiation Factor 2*
Periodontal Ligament*
Bone Morphogenetic Protein 2 ; Cell Differentiation ; Cells, Cultured ; Fibroblasts ; Humans ; Interleukin-1beta ; Osteoblasts ; Osteogenesis
Czasopismo naukowe

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