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Tytuł:
Progression analysis versus traditional methods to quantify slowing of disease progression in Alzheimer's disease.
Autorzy:
Jönsson L; Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, 171 64, Sweden. .
Ivkovic M; Novo Nordisk A/S, Søborg, Denmark.
Atri A; Banner Sun Health Research Institute and Banner Alzheimer's Institute, Banner Health, Sun City and Phoenix, AZ, USA.; Center for Brain/Mind Medicine, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Handels R; Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, 171 64, Sweden.; Faculty of Health, Medicine and Life Sciences, School for Mental Health and Neuroscience, Department of Psychiatry and Neuropsychology, Alzheimer Centre Limburg, Maastricht University Medical Centre+, Maastricht, MD, 6200, The Netherlands.
Gustavsson A; Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, 171 64, Sweden.; Quantify Research, Hantverkargatan 8, Stockholm, 112 21, Sweden.
Hahn-Pedersen JH; Novo Nordisk A/S, Søborg, Denmark.
León T; Novo Nordisk A/S, Søborg, Denmark.
Lilja M; Quantify Research, Hantverkargatan 8, Stockholm, 112 21, Sweden.
Gundgaard J; Novo Nordisk A/S, Søborg, Denmark.
Raket LL; Novo Nordisk A/S, Søborg, Denmark.; Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Lund, Sweden.
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Źródło:
Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Feb 29; Vol. 16 (1), pp. 48. Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/diagnostic imaging
Alzheimer Disease*/drug therapy
Cognitive Dysfunction*/diagnostic imaging
Cognitive Dysfunction*/drug therapy
Humans ; Disease Progression ; Mental Status and Dementia Tests ; Research Design ; Clinical Trials as Topic ; Models, Theoretical
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Unravelling the genomic origins of lumpy skin disease virus in recent outbreaks.
Autorzy:
Yadav P; Department of Biochemistry, Indian Institute of Science, Bangalore, 560012, India.
Kumar A; Department of Biochemistry, Indian Institute of Science, Bangalore, 560012, India.
Nath SS; Department of Biochemistry, Indian Institute of Science, Bangalore, 560012, India.
Devasurmutt Y; Department of Biochemistry, Indian Institute of Science, Bangalore, 560012, India.
Shashidhar G; Central Research Laboratory, KIMS, Bangalore, 560070, India.
Joshi M; Gujarat Biotechnology Research Centre, Gandhinagar, 382011, India.
Puvar A; Gujarat Biotechnology Research Centre, Gandhinagar, 382011, India.
Sharma S; Gujarat Biotechnology Research Centre, Gandhinagar, 382011, India.
Raval J; Gujarat Biotechnology Research Centre, Gandhinagar, 382011, India.
Pandit R; Gujarat Biotechnology Research Centre, Gandhinagar, 382011, India.
Chavda P; Gujarat Biotechnology Research Centre, Gandhinagar, 382011, India.
Nagaraj S; ICAR-National Institute of Veterinary Epidemiology and Disease Informatics, Bangalore, 560064, India.
Revanaiah Y; ICAR-National Institute of Veterinary Epidemiology and Disease Informatics, Bangalore, 560064, India.
Patil D; Kamdhenu University, Gandhinagar, Gujarat, India.
Raval SK; Kamdhenu University, Gandhinagar, Gujarat, India.
Raval J; Kamdhenu University, Gandhinagar, Gujarat, India.
Kanani A; AH Department, GoG, Gujarat, India.
Thakar F; AH Department, GoG, Gujarat, India.
Kumar N; National Centre for Veterinary Type Cultures, ICAR-NRC on Equines, Sirsa Road, Hisar, Haryana, 125001, India.
Reddy GBM; ICAR-National Institute of Veterinary Epidemiology and Disease Informatics, Bangalore, 560064, India.
Joshi C; Gujarat Biotechnology Research Centre, Gandhinagar, 382011, India.
Gulati BR; ICAR-National Institute of Veterinary Epidemiology and Disease Informatics, Bangalore, 560064, India.
Tatu U; Department of Biochemistry, Indian Institute of Science, Bangalore, 560012, India. .
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Źródło:
BMC genomics [BMC Genomics] 2024 Feb 19; Vol. 25 (1), pp. 196. Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:
Journal Article
MeSH Terms:
Lumpy skin disease virus*/genetics
Lumpy Skin Disease*/epidemiology
Lumpy Skin Disease*/genetics
Animals ; Cattle ; Phylogeny ; Genomics ; Disease Outbreaks
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Comparative Biochemical and Pathological Evaluation of Brain Samples from Knock-In Murine Models of Gaucher Disease.
Autorzy:
Furderer ML; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.
Berhe B; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.
Chen TC; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.
Wincovitch S; Advanced Imaging & Analysis Core, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Jiang X; Washington University Metabolomics Facility, Washington University School of Medicine, St. Louis, MO 63110, USA.
Tayebi N; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.
Sidransky E; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.
Han TU; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 02; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
Gaucher Disease*/genetics
Gaucher Disease*/pathology
Psychosine/*analogs & derivatives
Mice ; Humans ; Animals ; Aged ; Glucosylceramidase/genetics ; Glucosylceramidase/metabolism ; Disease Models, Animal ; Brain/metabolism ; alpha-Synuclein/genetics ; alpha-Synuclein/metabolism ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Minimal clinically important differences in six-minute walking distance in late-onset Pompe disease.
Autorzy:
Claeys KG; Department of Neurology, University Hospitals Leuven, Leuven, Belgium.; Department of Neurosciences, Laboratory for Muscle Diseases and Neuropathies, KU Leuven, Leuven Brain Institute (LBI), Leuven, Belgium.
Kushlaf H; University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Raza S; Amicus Therapeutics, Ltd., Marlow, UK.
Hummel N; Certara GmbH, Lörrach, Germany.
Shohet S; Amicus Therapeutics, Ltd., Marlow, UK.
Keyzor I; Amicus Therapeutics, Ltd., Marlow, UK.
Kopiec A; Certara, Krakow, Poland.
Graham R; Amicus Therapeutics, Inc., Princeton, NJ, USA.
Fox B; Amicus Therapeutics, Inc., Princeton, NJ, USA.
Schoser B; Department of Neurology, Friedrich-Baur-Institute, Ludwig-Maximilians-University, Munich, Germany. .
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Źródło:
Orphanet journal of rare diseases [Orphanet J Rare Dis] 2024 Apr 11; Vol. 19 (1), pp. 154. Date of Electronic Publication: 2024 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Glycogen Storage Disease Type II*
Humans ; Minimal Clinically Important Difference ; Disease Progression ; Walking
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Neuroinflammation increases oxygen extraction in a mouse model of Alzheimer's disease.
Autorzy:
Liu C; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA.
Cárdenas-Rivera A; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA.
Teitelbaum S; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA.
Birmingham A; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA.
Alfadhel M; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA.
Yaseen MA; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA. .
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Źródło:
Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Apr 10; Vol. 16 (1), pp. 78. Date of Electronic Publication: 2024 Apr 10.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/genetics
Alzheimer Disease*/metabolism
Mice ; Animals ; Mice, Transgenic ; Neuroinflammatory Diseases ; Cerebrovascular Circulation/physiology ; Disease Models, Animal ; Oxygen
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Impact of the COVID-19 outbreak and interventions on hand, foot and mouth disease in Zhengzhou, China, 2014-2022: a retrospective study.
Autorzy:
Jia W; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, No. 1, South University Road, Erqi District, 450018, Zhengzhou, China.
Zhang X; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, No. 1, South University Road, Erqi District, 450018, Zhengzhou, China.
Sun R; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, No. 1, South University Road, Erqi District, 450018, Zhengzhou, China.
Li P; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, No. 1, South University Road, Erqi District, 450018, Zhengzhou, China.
Song C; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, No. 1, South University Road, Erqi District, 450018, Zhengzhou, China. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2024 Apr 09; Vol. 24 (1), pp. 386. Date of Electronic Publication: 2024 Apr 09.
Typ publikacji:
Journal Article
MeSH Terms:
Hand, Foot and Mouth Disease*/epidemiology
Hand, Foot and Mouth Disease*/prevention & control
COVID-19*/epidemiology
COVID-19*/prevention & control
Child ; Humans ; Retrospective Studies ; Disease Outbreaks/prevention & control ; Incidence ; China/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Seroprevalence and molecular detection of foot and mouth disease virus in cattle in selected districts of Wolaita Zone, Southern Ethiopia.
Autorzy:
Bandaw T; School of Veterinary Medicine, Wolaita Sodo University, P. O. Box 138, Wolaita Sodo, Ethiopia.
Gebremeskel HF; School of Veterinary Medicine, Wolaita Sodo University, P. O. Box 138, Wolaita Sodo, Ethiopia. .
Muluneh A; Animal Health Institute, P. O. Box 04, Sebeta, Ethiopia.
Mengistu TS; School of Veterinary Medicine, Wolaita Sodo University, P. O. Box 138, Wolaita Sodo, Ethiopia.
Kebede IA; School of Veterinary Medicine, Ambo University, P. O. Box 19, Guder, Ethiopia. .
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Źródło:
Scientific reports [Sci Rep] 2024 Apr 04; Vol. 14 (1), pp. 7929. Date of Electronic Publication: 2024 Apr 04.
Typ publikacji:
Journal Article
MeSH Terms:
Foot-and-Mouth Disease Virus*/genetics
Cattle Diseases*/diagnosis
Cattle Diseases*/epidemiology
Foot-and-Mouth Disease*/diagnosis
Foot-and-Mouth Disease*/epidemiology
Humans ; Cattle ; Animals ; Seroepidemiologic Studies ; Cross-Sectional Studies ; Ethiopia/epidemiology ; Serogroup ; Disease Outbreaks/veterinary ; Animals, Wild ; Antibodies, Viral
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genome-wide analyses in Lyme borreliosis: identification of a genetic variant associated with disease susceptibility and its immunological implications.
Autorzy:
Vrijmoeth HD; Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands.
Ursinus J; Department of Internal Medicine, Division of Infectious Diseases, Amsterdam UMC, Location AMC, University of Amsterdam, P.O. Box 22660, Amsterdam, 1100 DD, the Netherlands.; Amsterdam Institute for Infection and Immunity, Amsterdam, the Netherlands.
Botey-Bataller J; Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands.; Department of Computational Biology for Individualised Infection Medicine, Centre for Individualised Infection Medicine, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.; TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.
Kuijpers Y; Department of Computational Biology for Individualised Infection Medicine, Centre for Individualised Infection Medicine, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.; TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.
Chu X; Department of Computational Biology for Individualised Infection Medicine, Centre for Individualised Infection Medicine, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.; TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.
van de Schoor FR; Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands.
Scicluna BP; Department of Applied Biomedical Science, Faculty of Health Sciences, Mater Dei Hospital, University of Malta, MSD 2080, Msida, Malta.; Centre for Molecular Medicine and Biobanking, Biomedical Sciences, University of Malta, MSD 2080, Msida, Malta.
Xu CJ; Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands.; Department of Computational Biology for Individualised Infection Medicine, Centre for Individualised Infection Medicine, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.; TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.
Netea MG; Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands.; Department of Immunology and Metabolism, Life and Medical Sciences Institute, University of Bonn, 53113, Bonn, Germany.
Kullberg BJ; Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands.
van den Wijngaard CC; National Institute for Public Health and Environment (RIVM), Center for Infectious Disease Control, Bilthoven, 3720 BA, the Netherlands.
Li Y; Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands.; Department of Computational Biology for Individualised Infection Medicine, Centre for Individualised Infection Medicine, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.; TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.
Hovius JW; Department of Internal Medicine, Division of Infectious Diseases, Amsterdam UMC, Location AMC, University of Amsterdam, P.O. Box 22660, Amsterdam, 1100 DD, the Netherlands.; Amsterdam Institute for Infection and Immunity, Amsterdam, the Netherlands.
Joosten LAB; Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2024 Mar 21; Vol. 24 (1), pp. 337. Date of Electronic Publication: 2024 Mar 21.
Typ publikacji:
Journal Article
MeSH Terms:
Lyme Disease*/genetics
Lyme Disease*/diagnosis
Borrelia burgdorferi*/genetics
Borrelia*
Borrelia burgdorferi Group*/genetics
Humans ; Genome-Wide Association Study ; Prospective Studies ; Leukocytes, Mononuclear ; Disease Susceptibility ; Cytokines/genetics ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/therapeutic use ; Secretoglobins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparing a pre-defined versus deep learning approach for extracting brain atrophy patterns to predict cognitive decline due to Alzheimer's disease in patients with mild cognitive symptoms.
Autorzy:
Arvidsson I; Centre for Mathematical Sciences, Lund University, Lund, Sweden. .
Strandberg O; Clinical Memory Research Unit, Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden.
Palmqvist S; Clinical Memory Research Unit, Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden.
Stomrud E; Clinical Memory Research Unit, Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden.
Cullen N; Clinical Memory Research Unit, Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden.
Janelidze S; Clinical Memory Research Unit, Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden.
Tideman P; Clinical Memory Research Unit, Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden.
Heyden A; Centre for Mathematical Sciences, Lund University, Lund, Sweden.
Åström K; Centre for Mathematical Sciences, Lund University, Lund, Sweden.
Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden.
Mattsson-Carlgren N; Clinical Memory Research Unit, Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden. .; Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden. .; Department of Neurology, Skåne University Hospital, Lund, Sweden. .
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Źródło:
Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Mar 19; Vol. 16 (1), pp. 61. Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/complications
Alzheimer Disease*/diagnostic imaging
Deep Learning*
Cognitive Dysfunction*/diagnosis
Humans ; Biomarkers ; Magnetic Resonance Imaging ; Brain/diagnostic imaging ; Brain/pathology ; Cognition ; Atrophy/pathology ; Disease Progression
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Chicoric Acid Ameliorated Beta-Amyloid Pathology and Enhanced Expression of Synaptic-Function-Related Markers via L1CAM in Alzheimer's Disease Models.
Autorzy:
Wang R; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.; School of Integrated Chinese and Western Medicine, Dalian Medical University, Dalian 116044, China.
Kang S; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.; School of Basic Medical Sciences, Dalian Medical University, Dalian 116044, China.
Zhao Z; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.; School of Integrated Chinese and Western Medicine, Dalian Medical University, Dalian 116044, China.
Jin L; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.
Cui X; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.
Chen L; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.
Schachner M; Keck Center for Collaborative Neuroscience and Department of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
Li S; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.; Department of Biochemistry, School of Basic Medical Science, Dalian Medical University, Dalian 116044, China.
Guo Y; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.; Department of Microecology, School of Basic Medical Science, Dalian Medical University, Dalian 116044, China.
Zhao J; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 17; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 17.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/drug therapy
Alzheimer Disease*/genetics
Alzheimer Disease*/metabolism
Neural Cell Adhesion Molecule L1*
Neurodegenerative Diseases*
Neuroblastoma*
Caffeic Acids*
Succinates*
Humans ; Mice ; Animals ; Amyloid Precursor Protein Secretases/genetics ; Amyloid Precursor Protein Secretases/metabolism ; Amyloid beta-Protein Precursor/metabolism ; Mice, Transgenic ; Disease Models, Animal ; Aspartic Acid Endopeptidases/metabolism ; Amyloid beta-Peptides/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genetic and Metabolic Characteristics of Lean Nonalcoholic Fatty Liver Disease in a Korean Health Examinee Cohort.
Autorzy:
Park H; Department of Family Medicine, Myoungji Hospital, Hanyang University College of Medicine, Goyang, Korea.
Yoon EL; Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Chung GE; Department of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.
Choe EK; Department of Surgery, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.
Bae JH; Department of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.
Choi SH; Department of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.
Kim M; Department of Radiology, Hanyang University College of Medicine, Seoul, Korea.
Hwang W; Hanyang Institute of Bioscience and Biotechnology, Department of Pre-Medicine, College of Medicine, Hanyang University, Seoul, Korea.
Kim HL; College of Pharmacy, Sahmyook University, Seoul, Korea.
Yang SY; Department of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.
Jun DW; Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.; Hanyang Institute of Bioscience and Biotechnology, Department of Pre-Medicine, College of Medicine, Hanyang University, Seoul, Korea.
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Źródło:
Gut and liver [Gut Liver] 2024 Mar 15; Vol. 18 (2), pp. 316-327. Date of Electronic Publication: 2023 Aug 10.
Typ publikacji:
Journal Article
MeSH Terms:
Non-alcoholic Fatty Liver Disease*/epidemiology
Non-alcoholic Fatty Liver Disease*/genetics
Non-alcoholic Fatty Liver Disease*/complications
Humans ; Retrospective Studies ; Cross-Sectional Studies ; Risk Factors ; Republic of Korea/epidemiology ; Polymorphism, Single Nucleotide ; Genetic Predisposition to Disease ; Liver/pathology ; Genotype
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Predicting long-term progression of Alzheimer's disease using a multimodal deep learning model incorporating interaction effects.
Autorzy:
Wang Y; Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang District, Shanghai, 200240, China.; SJTU-Yale Joint Center for Biostatistics and Data Science, Shanghai Jiao Tong University, Shanghai, China.
Gao R; Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang District, Shanghai, 200240, China.; SJTU-Yale Joint Center for Biostatistics and Data Science, Shanghai Jiao Tong University, Shanghai, China.
Wei T; Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang District, Shanghai, 200240, China.; SJTU-Yale Joint Center for Biostatistics and Data Science, Shanghai Jiao Tong University, Shanghai, China.
Johnston L; School of Mathematical Sciences, Shanghai Jiao Tong University, Shanghai, China.
Yuan X; Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang District, Shanghai, 200240, China.; SJTU-Yale Joint Center for Biostatistics and Data Science, Shanghai Jiao Tong University, Shanghai, China.
Zhang Y; Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang District, Shanghai, 200240, China.; SJTU-Yale Joint Center for Biostatistics and Data Science, Shanghai Jiao Tong University, Shanghai, China.
Yu Z; Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang District, Shanghai, 200240, China. .; SJTU-Yale Joint Center for Biostatistics and Data Science, Shanghai Jiao Tong University, Shanghai, China. .; School of Mathematical Sciences, Shanghai Jiao Tong University, Shanghai, China. .; Clinical Research Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China. .
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Corporate Authors:
Alzheimer’s Disease Neuroimaging Initiative
Źródło:
Journal of translational medicine [J Transl Med] 2024 Mar 11; Vol. 22 (1), pp. 265. Date of Electronic Publication: 2024 Mar 11.
Typ publikacji:
Multicenter Study; Journal Article
MeSH Terms:
Alzheimer Disease*/diagnostic imaging
Alzheimer Disease*/genetics
Deep Learning*
Cognitive Dysfunction*/diagnostic imaging
Cognitive Dysfunction*/genetics
Cognitive Dysfunction*/pathology
Humans ; Retrospective Studies ; Magnetic Resonance Imaging/methods ; Disease Progression
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Spermidine treatment: induction of autophagy but also apoptosis?
Autorzy:
Watchon M; Motor Neuron Disease Research Centre, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Level 1, 75 Talavera Rd, 2109, Sydney, NSW, Australia.
Wright AL; Motor Neuron Disease Research Centre, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Level 1, 75 Talavera Rd, 2109, Sydney, NSW, Australia.
Ahel HI; Motor Neuron Disease Research Centre, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Level 1, 75 Talavera Rd, 2109, Sydney, NSW, Australia.
Robinson KJ; Motor Neuron Disease Research Centre, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Level 1, 75 Talavera Rd, 2109, Sydney, NSW, Australia.
Plenderleith SK; Motor Neuron Disease Research Centre, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Level 1, 75 Talavera Rd, 2109, Sydney, NSW, Australia.
Kuriakose A; Motor Neuron Disease Research Centre, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Level 1, 75 Talavera Rd, 2109, Sydney, NSW, Australia.
Yuan KC; Motor Neuron Disease Research Centre, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Level 1, 75 Talavera Rd, 2109, Sydney, NSW, Australia.
Laird AS; Motor Neuron Disease Research Centre, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Level 1, 75 Talavera Rd, 2109, Sydney, NSW, Australia. .
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Źródło:
Molecular brain [Mol Brain] 2024 Mar 05; Vol. 17 (1), pp. 15. Date of Electronic Publication: 2024 Mar 05.
Typ publikacji:
Journal Article
MeSH Terms:
Neurodegenerative Diseases*
Machado-Joseph Disease*
Humans ; Animals ; Mice ; Spermidine/pharmacology ; Spermidine/therapeutic use ; Zebrafish ; Apoptosis ; Autophagy ; Disease Models, Animal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Using machine learning techniques to predict the risk of osteoporosis based on nationwide chronic disease data.
Autorzy:
Tu JB; Department of Orthopaedics, Xinfeng County People's Hospital, Jiangxi, 341600, Xinfeng, China.
Liao WJ; Department of ICU, GanZhou People's Hospital, GanZhou, 341000, Jiangxi, China.
Liu WC; Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 600 Yishan Road, Shanghai, 200233, China. .
Gao XH; Department of Orthopaedics, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, 510180, China. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 04; Vol. 14 (1), pp. 5245. Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
Osteoporosis*/diagnosis
Osteoporosis*/epidemiology
Neoplasms*
Pulmonary Disease, Chronic Obstructive*/diagnosis
Pulmonary Disease, Chronic Obstructive*/epidemiology
Humans ; Chronic Disease ; Machine Learning
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Regulation of nociception threshold by norepinephrine through adrenergic α2 receptor in rat models of Parkinson's disease.
Autorzy:
Gao Q; Department of Neurology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Zhang Y; Department of Neurology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Wang X; Department of Neurology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Wang R; Department of Neurology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Zhang L; Department of Neurology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Mar; Vol. 30 (3), pp. e14446. Date of Electronic Publication: 2023 Sep 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Norepinephrine*/metabolism
Parkinson Disease*/drug therapy
Parkinson Disease*/metabolism
Benzylamines*
Humans ; Rats ; Animals ; Oxidopamine/toxicity ; Saporins ; Guanfacine ; Nociception ; Yohimbine/pharmacology ; Adrenergic alpha-2 Receptor Agonists ; Pain ; Disease Models, Animal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Insights on the Use of Transgenic Mice Models in Alzheimer's Disease Research.
Autorzy:
Pádua MS; CIISA-Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinária, Universidade de Lisboa, 1300-477 Lisbon, Portugal.; Laboratório Associado para Ciência Animal e Veterinária (AL4AnimalS), Faculdade de Medicina Veterinária, Universidade de Lisboa, 1300-477 Lisbon, Portugal.
Guil-Guerrero JL; Departamento de Tecnología de Alimentos, Universidad de Almería, 04120 Almería, Spain.
Prates JAM; CIISA-Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinária, Universidade de Lisboa, 1300-477 Lisbon, Portugal.; Laboratório Associado para Ciência Animal e Veterinária (AL4AnimalS), Faculdade de Medicina Veterinária, Universidade de Lisboa, 1300-477 Lisbon, Portugal.
Lopes PA; CIISA-Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinária, Universidade de Lisboa, 1300-477 Lisbon, Portugal.; Laboratório Associado para Ciência Animal e Veterinária (AL4AnimalS), Faculdade de Medicina Veterinária, Universidade de Lisboa, 1300-477 Lisbon, Portugal.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 28; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Alzheimer Disease*/metabolism
Mice ; Animals ; Humans ; Mice, Transgenic ; Disease Models, Animal ; tau Proteins/metabolism ; Amyloid beta-Protein Precursor/metabolism ; Amyloid beta-Peptides/metabolism ; Presenilin-1/genetics ; Plaque, Amyloid/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
IgG4 disease with multiorgan involvement: a case report.
Autorzy:
Vidanapathirana MN; Professorial Medical Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka. .
Wijayaratne D; Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
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Źródło:
Journal of medical case reports [J Med Case Rep] 2024 Feb 28; Vol. 18 (1), pp. 115. Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Immunoglobulin G*
Immunoglobulin G4-Related Disease*/complications
Immunoglobulin G4-Related Disease*/diagnosis
Immunoglobulin G4-Related Disease*/drug therapy
Aged ; Humans ; Male ; Disease Progression ; Kidney/pathology ; Lung/diagnostic imaging ; Lung/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dimethyl fumarate improves cognitive impairment and neuroinflammation in mice with Alzheimer's disease.
Autorzy:
Wang T; Department of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University, Aichi, 464-8601, Japan.; Department of Neuroscience and Pathobiology, Nagoya University Graduate School of Medicine, Aichi, Japan.
Sobue A; Department of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University, Aichi, 464-8601, Japan. .; Medical Interactive Research and Academia Industry Collaboration Center, Research Institute of Environmental Medicine, Nagoya University, Aichi, Japan. .
Watanabe S; Department of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University, Aichi, 464-8601, Japan.
Komine O; Department of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University, Aichi, 464-8601, Japan.
Saido TC; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Saitama, Japan.
Saito T; Department of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University, Aichi, 464-8601, Japan.; Department of Neurocognitive Science, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, Aichi, Japan.
Yamanaka K; Department of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University, Aichi, 464-8601, Japan. .; Department of Neuroscience and Pathobiology, Nagoya University Graduate School of Medicine, Aichi, Japan. .; Institute for Glyco-Core Research (iGCORE), Nagoya University, Aichi, Japan. .; Center for One Medicine Innovative Translational Research (COMIT), Nagoya University, Nagoya, Aichi, Japan. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2024 Feb 21; Vol. 21 (1), pp. 55. Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/complications
Alzheimer Disease*/drug therapy
Alzheimer Disease*/genetics
Cognitive Dysfunction*/drug therapy
Cognitive Dysfunction*/etiology
Mice ; Animals ; Dimethyl Fumarate/pharmacology ; Dimethyl Fumarate/therapeutic use ; Mice, Transgenic ; Neuroinflammatory Diseases ; NF-E2-Related Factor 2/metabolism ; Disease Models, Animal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Association of blood cadmium concentration with chronic obstructive pulmonary disease progression: a prospective cohort study.
Autorzy:
Sun J; Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.; Institute of Respiratory Diseases, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.
Deng YP; Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.; Institute of Respiratory Diseases, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.
Xu J; Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.; Institute of Respiratory Diseases, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.
Zhu FM; Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.; Institute of Respiratory Diseases, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.
He QY; Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.; Institute of Respiratory Diseases, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.
Tang MM; Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.; Institute of Respiratory Diseases, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.
Liu Y; Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.; Institute of Respiratory Diseases, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.
Yang J; Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.; Institute of Respiratory Diseases, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.
Liu HY; Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.; Institute of Respiratory Diseases, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.; Center for Big Data and Population Health of IHM, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.
Fu L; Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China. .; Institute of Respiratory Diseases, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China. .; Center for Big Data and Population Health of IHM, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China. .
Zhao H; Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China. .; Institute of Respiratory Diseases, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China. .; Center for Big Data and Population Health of IHM, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China. .
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Źródło:
Respiratory research [Respir Res] 2024 Feb 17; Vol. 25 (1), pp. 91. Date of Electronic Publication: 2024 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
Cadmium*
Pulmonary Disease, Chronic Obstructive*/diagnosis
Pulmonary Disease, Chronic Obstructive*/epidemiology
Pulmonary Disease, Chronic Obstructive*/complications
Humans ; Prospective Studies ; Disease Progression ; Hospitalization
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Association of ADAMTS7 Gene Polymorphisms with the Risk of Coronary Artery Disease Occurrence and Cardiovascular Survival in the Polish Population: A Case-Control and a Prospective Cohort Study.
Autorzy:
Iwanicka J; Department of Biochemistry and Medical Genetics, School of Health Sciences in Katowice, Medical University of Silesia, Medykow Street 18, 40-752 Katowice, Poland.
Balcerzyk-Matić A; Department of Biochemistry and Medical Genetics, School of Health Sciences in Katowice, Medical University of Silesia, Medykow Street 18, 40-752 Katowice, Poland.
Iwanicki T; Department of Biochemistry and Medical Genetics, School of Health Sciences in Katowice, Medical University of Silesia, Medykow Street 18, 40-752 Katowice, Poland.
Mizia-Stec K; First Department of Cardiology, School of Medicine in Katowice, Medical University of Silesia, 47 Ziołowa St., 40-635 Katowice, Poland.
Bańka P; First Department of Cardiology, School of Medicine in Katowice, Medical University of Silesia, 47 Ziołowa St., 40-635 Katowice, Poland.
Filipecki A; First Department of Cardiology, School of Medicine in Katowice, Medical University of Silesia, 47 Ziołowa St., 40-635 Katowice, Poland.
Gawron K; Department of Molecular Biology and Genetics, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medykow 18, 40-752 Katowice, Poland.
Jarosz A; Department of Biochemistry and Medical Genetics, School of Health Sciences in Katowice, Medical University of Silesia, Medykow Street 18, 40-752 Katowice, Poland.
Nowak T; Department of Biochemistry and Medical Genetics, School of Health Sciences in Katowice, Medical University of Silesia, Medykow Street 18, 40-752 Katowice, Poland.
Krauze J; 1st Department of Cardiac Surgery/2nd Department of Cardiology, American Heart of Poland, S. A. Armii Krajowej 101, 43-316 Bielsko-Biala, Poland.
Niemiec P; Department of Biochemistry and Medical Genetics, School of Health Sciences in Katowice, Medical University of Silesia, Medykow Street 18, 40-752 Katowice, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 14; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
ADAMTS7 Protein*/genetics
Coronary Artery Disease*/epidemiology
Coronary Artery Disease*/genetics
Humans ; Case-Control Studies ; Gene Frequency ; Genetic Predisposition to Disease ; Genotype ; Poland/epidemiology ; Polymorphism, Single Nucleotide ; Prospective Studies ; Risk Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 4070323

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