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Wyszukujesz frazę ""dose response"" wg kryterium: Temat


Tytuł:
Methylphenidate dose-response in children with ADHD: evidence from a double-blind, randomized placebo-controlled titration trial.
Autorzy:
Vertessen K; Clinical Neuropsychology Section, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. .; Department of Child and Adolescent Psychiatry, University Psychiatric Centre KU Leuven, Leuven, Belgium. .; Child Study Group, Clinical Neuropsychology Section, Vrije Universiteit Amsterdam, Van der Boechorststraat, 7-9, 1081 BT, Amsterdam, The Netherlands. .
Luman M; Clinical Neuropsychology Section, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Levvel Specialists in Youth and Family Care, Amsterdam, The Netherlands.
Swanson JM; Department of Pediatrics, University of California, Irvine, USA.
Bottelier M; Child Study Center Accare, UMC Groningen, Groningen, The Netherlands.
Stoffelsen R; Levvel Specialists in Youth and Family Care, Amsterdam, The Netherlands.
Bet P; Department of Clinical Pharmacology and Pharmacy, Amsterdam UMC, VU Medical Center, Amsterdam, The Netherlands.
Wisse A; Youz, Center for Youth Menthal Healthcare, Velsen-Noord, The Netherlands.
Twisk JWR; Department of Epidemiology and Data Science, Amsterdam UMC, Amsterdam, The Netherlands.
Oosterlaan J; Clinical Neuropsychology Section, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Emma Neuroscience Group, Department of Pediatrics, Amsterdam Reproduction and Development, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
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Źródło:
European child & adolescent psychiatry [Eur Child Adolesc Psychiatry] 2024 Feb; Vol. 33 (2), pp. 495-504. Date of Electronic Publication: 2023 Mar 02.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Methylphenidate*/adverse effects
Attention Deficit Disorder with Hyperactivity*/drug therapy
Central Nervous System Stimulants*/adverse effects
Child ; Humans ; Child, Preschool ; Adolescent ; Dose-Response Relationship, Drug ; Double-Blind Method ; Treatment Outcome
Czasopismo naukowe
Tytuł:
A machine learning approach for predicting radiation-induced hypothyroidism in patients with nasopharyngeal carcinoma undergoing tomotherapy.
Autorzy:
Quan, Ke-Run (AUTHOR)
Lin, Wen-Rong (AUTHOR)
Hong, Jia-Biao (AUTHOR)
Lin, Yu-Hao (AUTHOR)
Chen, Kai-Qiang (AUTHOR)
Chen, Ji-Hong (AUTHOR)
Cheng, Pin-Jing (AUTHOR)
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Źródło:
Scientific Reports. 4/10/2024, Vol. 14 Issue 1, p1-11. 11p.
Czasopismo naukowe
Tytuł:
Sacral-Nerve-Sparing Planning Strategy in Pelvic Sarcomas/Chordomas Treated with Carbon-Ion Radiotherapy.
Autorzy:
Nachankar, Ankita (AUTHOR)
Schafasand, Mansure (AUTHOR)
Hug, Eugen (AUTHOR)
Martino, Giovanna (AUTHOR)
Góra, Joanna (AUTHOR)
Carlino, Antonio (AUTHOR)
Stock, Markus (AUTHOR)
Fossati, Piero (AUTHOR)
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Źródło:
Cancers. Apr2024, Vol. 16 Issue 7, p1284. 19p.
Czasopismo naukowe
Tytuł:
Baseline and early response 2-[18F]FDG-PET/MRI for prediction of radiotherapy outcome in uterine cervical squamous cell carcinoma: a prospective single-center observational cohort study.
Autorzy:
Strandberg, Sara (AUTHOR)
Jonsson, Joakim (AUTHOR)
Zarei, Maryam (AUTHOR)
Aglund, Kristina (AUTHOR)
Blomqvist, Lennart (AUTHOR)
Söderkvist, Karin (AUTHOR)
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Źródło:
European Journal of Hybrid Imaging. 3/1/2024, Vol. 8 Issue 1, p1-11. 11p.
Czasopismo naukowe
Tytuł:
Design, synthesis and in vitro anticancer activity of some new lomefloxacin derivatives.
Autorzy:
Adly ME; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, 33 Kasr El-Aini Street, Cairo, 11562, Egypt. .
Gedawy EM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, 33 Kasr El-Aini Street, Cairo, 11562, Egypt.; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Badr University in Cairo, Cairo, 11829, Egypt.
El-Malah AA; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, 33 Kasr El-Aini Street, Cairo, 11562, Egypt.
Khalil OM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, 33 Kasr El-Aini Street, Cairo, 11562, Egypt.
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 14; Vol. 14 (1), pp. 6175. Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/pharmacology
Fluoroquinolones*
Humans ; Molecular Structure ; Structure-Activity Relationship ; Cell Line, Tumor ; DNA Topoisomerases, Type II/metabolism ; Cell Proliferation ; Drug Screening Assays, Antitumor ; Molecular Docking Simulation ; Dose-Response Relationship, Drug
Czasopismo naukowe
Tytuł:
Efficacy and tolerability of adjunctive lacosamide in patients aged <4 years with focal seizures.
Autorzy:
Makedonska I; Municipal Non-profit Enterprise City Children's Clinical Hospital #6 of Dnipro City Council, Dnipro, Ukraine.
Ng YT; Baylor College of Medicine/The Children's Hospital of San Antonio, San Antonio, Texas, USA.
Beller C; UCB Pharma, Morrisville, North Carolina, USA.
Bozorg A; UCB Pharma, Morrisville, North Carolina, USA.
Csikós J; UCB Pharma, Monheim am Rhein, Germany.
McClung C; UCB Pharma, Morrisville, North Carolina, USA.
Moeltgen H; UCB Pharma, Monheim am Rhein, Germany.
Farkas MK; Pediatric Center, MTA Center of Excellence, Semmelweis University, Budapest, Hungary.
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Corporate Authors:
SP0967 Study Group
Źródło:
Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2024 Mar; Vol. 11 (3), pp. 768-779. Date of Electronic Publication: 2024 Feb 20.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Anticonvulsants*/adverse effects
Epilepsies, Partial*/drug therapy
Adult ; Child ; Humans ; Child, Preschool ; Lacosamide/adverse effects ; Reproducibility of Results ; Acetamides/adverse effects ; Drug Therapy, Combination ; Dose-Response Relationship, Drug ; Treatment Outcome ; Seizures/drug therapy ; Seizures/chemically induced
Czasopismo naukowe
Tytuł:
Synthesis and Antitumor Activity Evaluation of Novel Echinatin Derivatives with a 1,3,4-Oxadiazole Moiety.
Autorzy:
Tian X; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.
Sun Z; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.
Zhong Y; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.
Yang H; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.
Cheng M; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.
Liu Y; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 13; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/chemistry
Neoplasms*
Oxadiazoles*
Chalcones*
Humans ; Structure-Activity Relationship ; Drug Screening Assays, Antitumor ; Molecular Docking Simulation ; Cell Proliferation ; Molecular Structure ; Cell Line, Tumor ; Dose-Response Relationship, Drug
Czasopismo naukowe
Tytuł:
A new function for drug combination dose finding trials.
Autorzy:
Xiao J; Department of Financial and Actuarial Mathematics, Xi'an Jiaotong-Liverpool University, Suzhou, 215123, Jiangsu, China.
Zhang W; Department of Financial and Actuarial Mathematics, Xi'an Jiaotong-Liverpool University, Suzhou, 215123, Jiangsu, China. vivian_.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 12; Vol. 14 (1), pp. 3483. Date of Electronic Publication: 2024 Feb 12.
Typ publikacji:
Journal Article
MeSH Terms:
Research Design*
Reproducibility of Results ; Maximum Tolerated Dose ; Dose-Response Relationship, Drug ; Computer Simulation ; Bayes Theorem
Czasopismo naukowe
Tytuł:
Pharmacokinetic and safety profiles of mesalazine enema in healthy Chinese subjects: A single- and multiple-dose study.
Autorzy:
Cao Y; Clinical Trial Institute, Huashan Hospital, Fudan University, Shanghai, China.
Wang J; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Tang X; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Tian Y; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Yu J; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Liang H; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Wu J; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Chen Y; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Cao G; Clinical Trial Institute, Huashan Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Zhang J; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
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Źródło:
PloS one [PLoS One] 2024 Feb 02; Vol. 19 (2), pp. e0296940. Date of Electronic Publication: 2024 Feb 02 (Print Publication: 2024).
Typ publikacji:
Clinical Trial; Journal Article
MeSH Terms:
Mesalamine*/adverse effects
Tandem Mass Spectrometry*/methods
Humans ; Administration, Oral ; Area Under Curve ; China ; Chromatography, Liquid ; Dose-Response Relationship, Drug ; Healthy Volunteers
Czasopismo naukowe
Tytuł:
A flexible dose-response modeling framework based on continuous toxicity outcomes in phase I cancer clinical trials.
Autorzy:
Lee SY; Department of Statistics, Texas A &M University, 3143 TAMU, College Station, 77843, TX, USA. .
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Źródło:
Trials [Trials] 2023 Nov 21; Vol. 24 (1), pp. 745. Date of Electronic Publication: 2023 Nov 21.
Typ publikacji:
Clinical Trial, Phase I; Journal Article
MeSH Terms:
Antineoplastic Agents*/adverse effects
Neoplasms*/drug therapy
Humans ; Bayes Theorem ; Computer Simulation ; Dose-Response Relationship, Drug ; Probability ; Research Design
Czasopismo naukowe
Tytuł:
Ionizing radiation responses appear incidental to desiccation responses in the bdelloid rotifer Adineta vaga.
Autorzy:
Moris, Victoria C. (AUTHOR)
Bruneau, Lucie (AUTHOR)
Berthe, Jérémy (AUTHOR)
Heuskin, Anne-Catherine (AUTHOR)
Penninckx, Sébastien (AUTHOR)
Ritter, Sylvia (AUTHOR)
Weber, Uli (AUTHOR)
Durante, Marco (AUTHOR)
Danchin, Etienne G. J. (AUTHOR)
Hespeels, Boris (AUTHOR)
Doninck, Karine Van (AUTHOR)
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Źródło:
BMC Biology. 1/25/2024, Vol. 22 Issue 1, p1-27. 27p.
Czasopismo naukowe
Tytuł:
Assembling Au8 clusters on surfaces of bifunctional nanoimmunomodulators for synergistically enhanced low dose radiotherapy of metastatic tumor.
Autorzy:
Zhang, Rui (AUTHOR)
Jia, Mengchao (AUTHOR)
Lv, Hongying (AUTHOR)
Li, Mengxuan (AUTHOR)
Ding, Guanwen (AUTHOR)
Cheng, Ge (AUTHOR)
Li, Juan (AUTHOR)
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Źródło:
Journal of Nanobiotechnology. 1/5/2024, Vol. 22 Issue 1, p1-16. 16p.
Czasopismo naukowe
Tytuł:
Role of the mechanical microenvironment on CD-44 expression of breast adenocarcinoma in response to radiotherapy.
Autorzy:
Frascogna, Crescenzo (AUTHOR)
Mottareale, Rocco (AUTHOR)
La Verde, Giuseppe (AUTHOR)
Arrichiello, Cecilia (AUTHOR)
Muto, Paolo (AUTHOR)
Netti, Paolo A. (AUTHOR)
Pugliese, Mariagabriella (AUTHOR)
Panzetta, Valeria (AUTHOR)
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Źródło:
Scientific Reports. 1/3/2024, Vol. 13 Issue 1, p1-12. 12p.
Czasopismo naukowe
Tytuł:
Modulation of CD8 + T Cell Responses by Radiotherapy—Current Evidence and Rationale for Combination with Immune Checkpoint Inhibitors.
Autorzy:
Jeon, Seung Hyuck (AUTHOR)
Song, Changhoon (AUTHOR)
Eom, Keun-Yong (AUTHOR)
Kim, In Ah (AUTHOR)
Kim, Jae-Sung (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Dec2023, Vol. 24 Issue 23, p16691. 19p.
Czasopismo naukowe
Tytuł:
Enhancement of Radiation Sensitivity by Cathepsin L Suppression in Colon Carcinoma Cells.
Autorzy:
Abdelaziz, Ramadan F. (AUTHOR)
Hussein, Ahmed M. (AUTHOR)
Kotob, Mohamed H. (AUTHOR)
Weiss, Christina (AUTHOR)
Chelminski, Krzysztof (AUTHOR)
Stojanovic, Tamara (AUTHOR)
Studenik, Christian R. (AUTHOR)
Aufy, Mohammed (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Dec2023, Vol. 24 Issue 23, p17106. 19p.
Czasopismo naukowe
Tytuł:
Nanoparticle-Mediated Radiotherapy: Unraveling Dose Enhancement and Apoptotic Responses in Cancer and Normal Cell Lines.
Autorzy:
Kouri, Maria Anthi (AUTHOR)
Spyratou, Ellas (AUTHOR)
Kalkou, Maria-Eleni (AUTHOR)
Patatoukas, Georgios (AUTHOR)
Angelopoulou, Evangelia (AUTHOR)
Tremi, Ioanna (AUTHOR)
Havaki, Sophia (AUTHOR)
Gorgoulis, Vassilis G. (AUTHOR)
Kouloulias, Vassilis (AUTHOR)
Platoni, Kalliopi (AUTHOR)
Efstathopoulos, Efstathios P. (AUTHOR)
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Źródło:
Biomolecules (2218-273X). Dec2023, Vol. 13 Issue 12, p1720. 15p.
Czasopismo naukowe

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