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Tytuł:
Effect of Perineural or Intravenous Betamethasone on Femoral Nerve Block Outcomes in Knee Arthroplasty: A Randomized, Controlled Study.
Autorzy:
Li B; Department of Orthopedics, Qilu Hospital of Shandong University, Jinan, China.; Shandong University Cheeloo College of Medicine, Jinan, China.
Yang X; Shandong University Cheeloo College of Medicine, Jinan, China.; Department of Anaesthesiology, Qilu Hospital, Shandong University, Jinan, China.; Department of Cardiology, the Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, the State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Qilu Hospital of Shandong University, Jinan, China.
Liu F; Shandong University Cheeloo College of Medicine, Jinan, China.; Department of Anaesthesiology, Qilu Hospital, Shandong University, Jinan, China.
Huang H; Institute for In Vitro Sciences, Gaithersburg, MD, USA.
Zhang B; Department of Orthopedics, Qilu Hospital of Shandong University, Jinan, China.
Li X; Department of Orthopedics, Qilu Hospital of Shandong University, Jinan, China.
Lu Q; Department of Orthopedics, Qilu Hospital of Shandong University, Jinan, China.
Liu P; Department of Orthopedics, Qilu Hospital of Shandong University, Jinan, China.
Fan L; Department of Anaesthesiology, Qilu Hospital, Shandong University, Jinan, China.
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Źródło:
Orthopaedic surgery [Orthop Surg] 2024 Apr; Vol. 16 (4), pp. 873-881. Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Arthroplasty, Replacement, Knee*/adverse effects
Femoral Nerve*/drug effects
Nerve Block*
Ropivacaine*/administration & dosage
Betamethasone*/administration & dosage
Humans ; Administration, Intravenous ; Amides/adverse effects ; Anesthetics, Local/administration & dosage ; C-Reactive Protein/drug effects ; C-Reactive Protein/metabolism ; Double-Blind Method ; Pain, Postoperative/drug therapy ; Pain, Postoperative/prevention & control ; Saline Solution/pharmacology ; Saline Solution/therapeutic use ; Tumor Necrosis Factor-alpha/blood ; Tumor Necrosis Factor-alpha/drug effects ; Interleukin-1beta/blood ; Interleukin-1beta/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Vitamin A resolves lineage plasticity to orchestrate stem cell lineage choices.
Autorzy:
Tierney MT; Howard Hughes Medical Institute, Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY 10065, USA.
Polak L; Howard Hughes Medical Institute, Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY 10065, USA.
Yang Y; Howard Hughes Medical Institute, Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY 10065, USA.
Abdusselamoglu MD; Howard Hughes Medical Institute, Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY 10065, USA.
Baek I; Howard Hughes Medical Institute, Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY 10065, USA.
Stewart KS; Howard Hughes Medical Institute, Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY 10065, USA.
Fuchs E; Howard Hughes Medical Institute, Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY 10065, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Mar 08; Vol. 383 (6687), pp. eadi7342. Date of Electronic Publication: 2024 Mar 08.
Typ publikacji:
Journal Article
MeSH Terms:
Adult Stem Cells*/cytology
Adult Stem Cells*/physiology
Cell Plasticity*/drug effects
Cell Plasticity*/physiology
Epidermis*/drug effects
Epidermis*/physiology
Hair Follicle*/cytology
Hair Follicle*/drug effects
Hair Follicle*/physiology
Tretinoin*/metabolism
Tretinoin*/pharmacology
Wound Healing*/drug effects
Wound Healing*/physiology
Animals ; Mice ; Cell Lineage/drug effects ; Cell Lineage/physiology ; Rejuvenation/physiology ; Cell Culture Techniques ; Neoplasms/pathology ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model.
Autorzy:
Tan B; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Zhang X; Department Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA.
Ansari A; Center for Advanced Biotechnology and Medicine, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.; Department of Chemistry and Chemical Biology, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Jadhav P; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Tan H; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Li K; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Chopra A; Center for Advanced Biotechnology and Medicine, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.; Department of Chemistry and Chemical Biology, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Ford A; Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA.
Chi X; Department Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA.
Ruiz FX; Center for Advanced Biotechnology and Medicine, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.; Department of Chemistry and Chemical Biology, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Arnold E; Center for Advanced Biotechnology and Medicine, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.; Department of Chemistry and Chemical Biology, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Deng X; Department Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA.; Oklahoma Center for Respiratory and Infectious Diseases, Oklahoma State University, Stillwater, OK 74078, USA.
Wang J; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Mar 29; Vol. 383 (6690), pp. 1434-1440. Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:
Journal Article
MeSH Terms:
Coronavirus Papain-Like Proteases*/antagonists & inhibitors
Coronavirus Papain-Like Proteases*/chemistry
COVID-19*
SARS-CoV-2*/drug effects
SARS-CoV-2*/enzymology
Coronavirus Protease Inhibitors*/administration & dosage
Coronavirus Protease Inhibitors*/chemistry
Coronavirus Protease Inhibitors*/pharmacology
Drug Design*
COVID-19 Drug Treatment*
Animals ; Mice ; Disease Models, Animal ; Administration, Oral ; Crystallography, X-Ray ; Structure-Activity Relationship ; Viral Load/drug effects ; Male ; Mice, Inbred C57BL ; Mice, Inbred BALB C
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
SUMOylation Inhibition Enhances Protein Transcription under CMV Promoter: A Lesson from a Study with the F508del-CFTR Mutant.
Autorzy:
Borgo C; Department of Biomedical Sciences, University of Padova, 35131 Padova, Italy.
D'Amore C; Department of Biomedical Sciences, University of Padova, 35131 Padova, Italy.
Capurro V; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, 16147 Genova, Italy.
Tomati V; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, 16147 Genova, Italy.
Pedemonte N; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, 16147 Genova, Italy.
Bosello Travain V; Department of Molecular Medicine, University of Padova, 35131 Padova, Italy.
Salvi M; Department of Biomedical Sciences, University of Padova, 35131 Padova, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 15; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
Cystic Fibrosis*/drug therapy
Cystic Fibrosis*/genetics
Cystic Fibrosis*/metabolism
Cystic Fibrosis Transmembrane Conductance Regulator*/genetics
Cystic Fibrosis Transmembrane Conductance Regulator*/metabolism
Sumoylation*/drug effects
Humans ; Cytomegalovirus ; Mutation ; Promoter Regions, Genetic/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Punicalagin attenuates ventricular remodeling after acute myocardial infarction via regulating the NLRP3/caspase-1 pathway.
Autorzy:
Peng JF; Department of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, Anhui, China.
Zhao XN; Department of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, Anhui, China.
Zhang M; Department of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, Anhui, China.
Li JY; Department of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, Anhui, China.
Zhao CC; Department of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, Anhui, China.
Wang SS; Department of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, Anhui, China.
Wang JL; Department of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, Anhui, China.
Shi H; Department of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, Anhui, China.
Zhou P; Department of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, Anhui, China.; Research Institute of Integrated Traditional Chinese and Western Medicine, Anhui Academy of Chinese Medicine, Hefei, Anhui, China.
Wang L; Department of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, Anhui, China.; Research Institute of Integrated Traditional Chinese and Western Medicine, Anhui Academy of Chinese Medicine, Hefei, Anhui, China.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2023 Dec; Vol. 61 (1), pp. 963-972.
Typ publikacji:
Journal Article
MeSH Terms:
Hydrolyzable Tannins*/administration & dosage
Ventricular Remodeling*/drug effects
Myocardial Infarction*/drug therapy
Myocardial Infarction*/pathology
Signal Transduction*/drug effects
Animals ; Rats ; Male ; Rats, Sprague-Dawley ; Molecular Docking Simulation ; Fibrosis/drug therapy ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/pathology ; Apoptosis/drug effects ; Caspase 1/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The dopamine receptor D1 inhibitor, SKF83566, suppresses GBM stemness and invasion through the DRD1-c-Myc-UHRF1 interactions.
Autorzy:
Xue Z; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Zhang Y; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Zhao R; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Liu X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Grützmann K; Core Unit for Molecular Tumour Diagnostics (CMTD), National Center for Tumour Diseases (NCT) Dresden, Dresden, Germany.; Institute for Medical Informatics and Biometry, Medical Faculty, TU Dresden, Dresden, Germany.
Klink B; Department of Genetics, Laboratoire National de Santé, Dudelange, Luxembourg.
Zhang X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Wang S; Department of Neurosurgery, NYU Grossman School of Medicine, New York, NY, 10016, USA.
Zhao W; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Sun Y; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Han M; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Wang X; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Hu Y; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Liu X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Yang N; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Qiu C; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.; Department of Radiation Oncology, Qilu Hospital of Shandong University, Jinan, China.
Li W; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Huang B; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Li X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Bjerkvig R; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Department of Biomedicine, University of Bergen, Jonas Lies vei 91, Bergen, 5009, Norway.
Wang J; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China. .; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China. .; Department of Biomedicine, University of Bergen, Jonas Lies vei 91, Bergen, 5009, Norway. .
Zhou W; Department of Blood Transfusion, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Jan 22; Vol. 43 (1), pp. 25. Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:
Journal Article
MeSH Terms:
Glioblastoma*/drug therapy
Glioblastoma*/genetics
Glioma*
Dopamine Antagonists*/metabolism
Dopamine Antagonists*/pharmacology
Proto-Oncogene Proteins c-myc*/drug effects
Proto-Oncogene Proteins c-myc*/metabolism
Animals ; Humans ; Mice ; Brain ; CCAAT-Enhancer-Binding Proteins/drug effects ; CCAAT-Enhancer-Binding Proteins/metabolism ; Dopamine ; Mice, Nude ; Multigene Family ; Receptors, Dopamine D1/antagonists & inhibitors ; Ubiquitin-Protein Ligases/drug effects ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Anti-inflammatory effects of reticuline on the JAK2/STAT3/SOCS3 and p38 MAPK/NF-κB signaling pathway in a mouse model of obesity-associated asthma.
Autorzy:
Lyu X; Department of Pediatrics, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Liu J; Department of Pediatrics, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Liu Z; Department of Pediatrics, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Wu Y; Department of Pediatrics, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Zhu P; Department of Pediatrics, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Liu C; Department of Pediatrics, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
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Źródło:
The clinical respiratory journal [Clin Respir J] 2024 Jan; Vol. 18 (1), pp. e13729.
Typ publikacji:
Journal Article
MeSH Terms:
Asthma*/drug therapy
Asthma*/metabolism
Benzylisoquinolines*/pharmacology
Benzylisoquinolines*/therapeutic use
Janus Kinase 2*/drug effects
Janus Kinase 2*/metabolism
NF-kappa B*/drug effects
NF-kappa B*/metabolism
STAT3 Transcription Factor*/drug effects
STAT3 Transcription Factor*/metabolism
Animals ; Mice ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Bronchoalveolar Lavage Fluid ; Cytokines/metabolism ; Disease Models, Animal ; Inflammation/metabolism ; Lung/pathology ; Mice, Inbred BALB C ; Obesity/complications ; Obesity/drug therapy ; p38 Mitogen-Activated Protein Kinases/metabolism ; p38 Mitogen-Activated Protein Kinases/pharmacology ; p38 Mitogen-Activated Protein Kinases/therapeutic use ; Signal Transduction ; Suppressor of Cytokine Signaling 3 Protein/drug effects ; Suppressor of Cytokine Signaling 3 Protein/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An AMPK agonist suppresses the progress of colorectal cancer by regulating the polarization of TAM to M1 through inhibition of HIF-1α and mTOR signal pathway.
Autorzy:
Cao Y; Department of Laboratory Medicine, Hangzhou Cancer Hospital, Affiliated Hangzhou Cancer Hospital, Zhejiang University School of Medicine, Shangcheng, China.
Wo M; Department of Clinical Laboratory, Zhejiang Provincial People's Hospital, Affiliated People's Hospital of Hangzhou Medical College, Zhejiang Center for Clinical Laboratory, Gongshu, China.
Xu C; Department of Laboratory Medicine, Affiliated Third Hospital of Zhejiang Traditional Chinese Medicine University, Xihu, Hangzhou, Zhejiang, China.
Fei X; Department of Clinical Laboratory, Zhejiang Provincial People's Hospital, Affiliated People's Hospital of Hangzhou Medical College, Zhejiang Center for Clinical Laboratory, Gongshu, China.
Jin J; Department of Clinical Laboratory, Zhejiang Provincial People's Hospital, Affiliated People's Hospital of Hangzhou Medical College, Zhejiang Center for Clinical Laboratory, Gongshu, China.
Shan Z; Department of Clinical Laboratory, Zhejiang Provincial People's Hospital, Affiliated People's Hospital of Hangzhou Medical College, Zhejiang Center for Clinical Laboratory, Gongshu, China.
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Źródło:
Journal of cancer research and therapeutics [J Cancer Res Ther] 2023 Dec 01; Vol. 19 (6), pp. 1560-1567. Date of Electronic Publication: 2023 Dec 28.
Typ publikacji:
Journal Article
MeSH Terms:
Metformin*/pharmacology
Metformin*/therapeutic use
Signal Transduction*/drug effects
TOR Serine-Threonine Kinases*/antagonists & inhibitors
TOR Serine-Threonine Kinases*/metabolism
Colorectal Neoplasms*/drug therapy
Tumor-Associated Macrophages*/drug effects
Hypoxia-Inducible Factor 1, alpha Subunit/antagonists & inhibitors ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; HCT116 Cells ; Cell Polarity/drug effects ; THP-1 Cells ; AMP-Activated Protein Kinases/antagonists & inhibitors ; AMP-Activated Protein Kinases/genetics ; AMP-Activated Protein Kinases/metabolism ; Gene Knockdown Techniques
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Gold Nanoparticles Downregulate IL-6 Expression/Production by Upregulating microRNA-26a-5p and Deactivating the RelA and NF-κBp50 Transcription Pathways in Activated Breast Cancer Cells.
Autorzy:
Farhana A; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi Arabia.
Alsrhani A; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi Arabia.
Alghsham RS; Department of Pathology, College of Medicine, Qassim University, Buraidah 51452, Saudi Arabia.
Derafa W; Department of Chemistry, College of Science, Jouf University, Aljouf 72388, Saudi Arabia.
Khan YS; Department of Anatomy, College of Medicine, Jouf University, Sakaka 72388, Saudi Arabia.
Rasheed Z; Department of Pathology, College of Medicine, Qassim University, Buraidah 51452, Saudi Arabia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 24; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 24.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Breast Neoplasms*/pathology
Metal Nanoparticles*/chemistry
MicroRNAs*/genetics
MicroRNAs*/metabolism
NF-kappa B*/drug effects
NF-kappa B*/metabolism
Female ; Humans ; 3' Untranslated Regions ; Gold ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Transcription Factor RelA/drug effects ; Transcription Factor RelA/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
QR-1011 restores defective ABCA4 splicing caused by multiple severe ABCA4 variants underlying Stargardt disease.
Autorzy:
Kaltak M; R&D Department, ProQR Therapeutics, Zernikedreef 9, 2333 CK, Leiden, The Netherlands.; Department of Human Genetics, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands.
de Bruijn P; R&D Department, ProQR Therapeutics, Zernikedreef 9, 2333 CK, Leiden, The Netherlands.
van Leeuwen W; R&D Department, ProQR Therapeutics, Zernikedreef 9, 2333 CK, Leiden, The Netherlands.
Platenburg G; R&D Department, ProQR Therapeutics, Zernikedreef 9, 2333 CK, Leiden, The Netherlands.
Cremers FPM; Department of Human Genetics, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands.
Collin RWJ; Department of Human Genetics, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands.
Swildens J; R&D Department, ProQR Therapeutics, Zernikedreef 9, 2333 CK, Leiden, The Netherlands. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 06; Vol. 14 (1), pp. 684. Date of Electronic Publication: 2024 Jan 06.
Typ publikacji:
Journal Article
MeSH Terms:
ATP-Binding Cassette Transporters*/genetics
Stargardt Disease*/drug therapy
Stargardt Disease*/genetics
Oligodeoxyribonucleotides, Antisense*/pharmacology
Organoids*/drug effects
Humans ; Exons ; Retina/cytology ; RNA Splicing/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
AC-73 and Syrosingopine Inhibit SARS-CoV-2 Entry into Megakaryocytes by Targeting CD147 and MCT4.
Autorzy:
Spinello I; National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Saulle E; National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Quaranta MT; National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Pelosi E; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.
Castelli G; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.
Cerio A; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.
Pasquini L; Core Facilities, Istituto Superiore di Sanità, 00161 Rome, Italy.
Morsilli O; Department of Cardiovascular, Endocrine-Metabolic Diseases and Ageing, Istituto Superiore di Sanità, 00161 Rome, Italy.
Dupuis ML; National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Labbaye C; National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
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Źródło:
Viruses [Viruses] 2024 Jan 04; Vol. 16 (1). Date of Electronic Publication: 2024 Jan 04.
Typ publikacji:
Journal Article
MeSH Terms:
Megakaryocytes*/virology
Phenols*/pharmacology
Reserpine*/analogs & derivatives
Reserpine*/pharmacology
SARS-CoV-2*/drug effects
Humans ; COVID-19 ; Post-Acute COVID-19 Syndrome ; Virus Internalization/drug effects
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Laminin fragments conjugated with perlecan's growth factor-binding domain differentiate human induced pluripotent stem cells into skin-derived precursor cells.
Autorzy:
Sugiyama-Nakagiri Y; Kao Corporation, 2602, Akabane Ichikai-Machi, Haga-gun, Tochigi, 321-3497, Japan. .
Yamashita S; Kao Corporation, 2602, Akabane Ichikai-Machi, Haga-gun, Tochigi, 321-3497, Japan.
Taniguchi Y; Division of Matrixome Research and Application, Institute for Protein Research, Osaka University, Suita, Osaka, Japan.
Shimono C; Division of Matrixome Research and Application, Institute for Protein Research, Osaka University, Suita, Osaka, Japan.
Sekiguchi K; Division of Matrixome Research and Application, Institute for Protein Research, Osaka University, Suita, Osaka, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 04; Vol. 13 (1), pp. 14556. Date of Electronic Publication: 2023 Sep 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation*/drug effects
Heparan Sulfate Proteoglycans*/chemistry
Induced Pluripotent Stem Cells*/cytology
Induced Pluripotent Stem Cells*/drug effects
Intercellular Signaling Peptides and Proteins*/metabolism
Laminin*/chemistry
Laminin*/pharmacology
Peptide Fragments*/chemistry
Peptide Fragments*/pharmacology
Protein Domains*
Skin*/cytology
Humans ; Adipocytes/cytology ; Adipocytes/drug effects ; Osteocytes/cytology ; Osteocytes/drug effects ; Schwann Cells/cytology ; Schwann Cells/drug effects ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The effect of mycophenolate mofetil on podocytes in nephrotoxic serum nephritis.
Autorzy:
Hackl A; Department of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany. .; CECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany. .
Nüsken E; Department of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
Voggel J; Department of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
Abo Zed SED; Department of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany.; CECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Binz-Lotter J; CECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.; Department 2 of Internal Medicine, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Unnersjö-Jess D; CECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.; Department 2 of Internal Medicine, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Müller C; Department of Therapeutic Drug Monitoring, Pharmacology at the Laboratory Centre, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Fink G; Department of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
Bohl K; CECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.; Department 2 of Internal Medicine, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Wiesner E; CECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.; Department 2 of Internal Medicine, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Diefenhardt P; CECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.; Department 2 of Internal Medicine, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Dafinger C; Department of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany.; CECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Chen H; CECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.; Department 2 of Internal Medicine, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Wohlfarth M; Department of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
Müller RU; CECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.; Department 2 of Internal Medicine, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Rare Kidney Diseases Cologne, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Hackl MJ; CECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.; Department 2 of Internal Medicine, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Schermer B; CECAD, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.; Department 2 of Internal Medicine, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Nüsken KD; Department of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
Weber LT; Department of Pediatrics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Street 62, 50937, Cologne, Germany.; Center for Rare Kidney Diseases Cologne, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 29; Vol. 13 (1), pp. 14167. Date of Electronic Publication: 2023 Aug 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mycophenolic Acid*/administration & dosage
Podocytes*/drug effects
Nephritis*/drug therapy
Nephritis*/pathology
Animals ; Mice ; Mice, Inbred C57BL ; Kidney Glomerulus/chemistry ; Kidney Glomerulus/pathology ; Proteome/drug effects ; Actin Cytoskeleton/drug effects
Czasopismo naukowe
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Tytuł:
Hydrogen Peroxide Inhibits Hepatitis B Virus Replication by Downregulating HBx Levels via Siah-1-Mediated Proteasomal Degradation in Human Hepatoma Cells.
Autorzy:
Yoon H; Department of Integrated Biological Science, The Graduate School, Pusan National University, Busan 46241, Republic of Korea.
Lee HK; Department of Integrated Biological Science, The Graduate School, Pusan National University, Busan 46241, Republic of Korea.
Jang KL; Department of Integrated Biological Science, The Graduate School, Pusan National University, Busan 46241, Republic of Korea.; Department of Microbiology, College of Natural Science, Pusan National University, Busan 46241, Republic of Korea.; Microbiological Resource Research Institute, Pusan National University, Busan 46241, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 28; Vol. 24 (17). Date of Electronic Publication: 2023 Aug 28.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/genetics
Hepatitis B*
Hepatitis B virus*/drug effects
Liver Neoplasms*/genetics
Humans ; Hydrogen Peroxide/pharmacology ; Tumor Suppressor Protein p53/genetics ; Virus Replication ; Viral Regulatory and Accessory Proteins/drug effects ; Trans-Activators/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ethanolic Extract Propolis-Loaded Niosomes Diminish Phospholipase B1, Biofilm Formation, and Intracellular Replication of Cryptococcus neoformans in Macrophages.
Autorzy:
Kietrungruang K; Division of Clinical Microbiology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Sookkree S; Division of Clinical Microbiology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Sangboonruang S; Division of Clinical Microbiology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Semakul N; Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
Poomanee W; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
Kitidee K; Center for Research Innovation and Biomedical Informatics, Faculty of Medical Technology, Mahidol University, Salaya, Nakhon Pathom 73170, Thailand.
Tragoolpua Y; Natural Extracts and Innovative Products for Alternative Healthcare Research Group, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.; Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
Tragoolpua K; Division of Clinical Microbiology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.; Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Aug 24; Vol. 28 (17). Date of Electronic Publication: 2023 Aug 24.
Typ publikacji:
Journal Article
MeSH Terms:
Biofilms*/drug effects
Cryptococcus neoformans*/drug effects
Cryptococcus neoformans*/enzymology
Cryptococcus neoformans*/pathogenicity
Fungal Proteins*/antagonists & inhibitors
Lysophospholipase*/antagonists & inhibitors
Macrophages, Alveolar*/microbiology
Propolis*/chemistry
Propolis*/pharmacology
Antifungal Agents*/chemistry
Antifungal Agents*/pharmacology
Humans ; Cell Line, Tumor ; Cryptococcosis/prevention & control ; Cryptococcosis/therapy ; Ethanol/chemistry ; Liposomes ; Lung Diseases, Fungal/prevention & control ; Lung Diseases, Fungal/therapy ; Virulence/drug effects ; Virulence Factors/antagonists & inhibitors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Antimicrobial, Antibiofilm, and Anticancer Activities of Syzygium aromaticum Essential Oil Nanoemulsion.
Autorzy:
Shehabeldine AM; Botany and Microbiology Department, Faculty of Science, Al-Azhar University, Nasr City 11884, Egypt.
Doghish AS; Department of Biochemistry, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City 11829, Egypt.; Biochemistry and Molecular Biology Department, Faculty of Pharmacy (Boys), Al-Azhar University, Nasr City 11231, Egypt.
El-Dakroury WA; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City 11829, Egypt.
Hassanin MMH; Ornamental, Medicinal and Aromatic Plant Disease Department, Plant Pathology Research Institute, Agricultural Research Center (ARC), Giza 12619, Egypt.
Al-Askar AA; Department of Botany and Microbiology, Faculty of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
AbdElgawad H; Integrated Molecular Plant Physiology Research (IMPRES), Department of Biology, University of Antwerp, 2022 Antwerp, Belgium.
Hashem AH; Botany and Microbiology Department, Faculty of Science, Al-Azhar University, Nasr City 11884, Egypt.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Aug 01; Vol. 28 (15). Date of Electronic Publication: 2023 Aug 01.
Typ publikacji:
Journal Article
MeSH Terms:
Biofilms*/drug effects
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacology
Oils, Volatile*/chemistry
Oils, Volatile*/pharmacology
Syzygium*/chemistry
Anti-Bacterial Agents*/chemistry
Anti-Bacterial Agents*/pharmacology
Antifungal Agents*/chemistry
Antifungal Agents*/pharmacology
Emulsions ; Dynamic Light Scattering ; Microscopy, Electron, Transmission ; Hep G2 Cells ; MCF-7 Cells ; Humans ; Apoptosis ; Nanoparticle Drug Delivery System ; Nanostructures/chemistry ; Staphylococcus aureus/drug effects ; Fungi/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification of side effects of COVID-19 drug candidates on embryogenesis using an integrated zebrafish screening platform.
Autorzy:
Ernst A; Institute of Anatomy, University of Bern, Bern, Switzerland.
Piragyte I; Institute of Anatomy, University of Bern, Bern, Switzerland.; Department for Biomedical Research DBMR, University of Bern, Bern, Switzerland.
Mp AM; Institute of Anatomy, University of Bern, Bern, Switzerland.; Department for Biomedical Research DBMR, University of Bern, Bern, Switzerland.
Le ND; Institute for Infectious Diseases, University of Bern, Bern, Switzerland.
Grandgirard D; Institute for Infectious Diseases, University of Bern, Bern, Switzerland.
Leib SL; Institute for Infectious Diseases, University of Bern, Bern, Switzerland.
Oates A; School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Mercader N; Institute of Anatomy, University of Bern, Bern, Switzerland. .; Department for Biomedical Research DBMR, University of Bern, Bern, Switzerland. .; Centro Nacional de Investigaciones Cardiovasculares, CNIC, Madrid, Spain. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 09; Vol. 13 (1), pp. 17037. Date of Electronic Publication: 2023 Oct 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiviral Agents*/pharmacology
Embryonic Development*/drug effects
Animals ; Female ; Humans ; Pregnancy ; COVID-19 ; COVID-19 Drug Treatment ; Ritonavir/pharmacology ; SARS-CoV-2 ; Zebrafish ; Embryo, Nonmammalian/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
AMPK inhibitor, compound C, inhibits coronavirus replication in vitro.
Autorzy:
Jang M; Division of Biological Science and Technology, Yonsei University, Wonju, Republic of Korea.
Park R; Department of Life Science, Yong-In University, Yongin, Republic of Korea.
Yamamoto A; Division of Biological Science and Technology, Yonsei University, Wonju, Republic of Korea.
Park YI; Division of Biological Science and Technology, Yonsei University, Wonju, Republic of Korea.
Park Y; Division of Biological Science and Technology, Yonsei University, Wonju, Republic of Korea.
Lee S; Division of Biological Science and Technology, Yonsei University, Wonju, Republic of Korea.
Park J; Division of Biological Science and Technology, Yonsei University, Wonju, Republic of Korea.
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Źródło:
PloS one [PLoS One] 2023 Oct 03; Vol. 18 (10), pp. e0292309. Date of Electronic Publication: 2023 Oct 03 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiviral Agents*/pharmacology
Coronavirus OC43, Human*/drug effects
Humans ; AMP-Activated Protein Kinases/antagonists & inhibitors ; Pyrazoles/pharmacology ; Virus Replication/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Nutrients mediate caffeine inhibition of Escherichia coli.
Autorzy:
McConnell MN; Division of Mathematics and Natural Sciences, Penn State Altoona, Pennsylvania State University, Altoona, Pennsylvania, USA.
Bakermans C; Division of Mathematics and Natural Sciences, Penn State Altoona, Pennsylvania State University, Altoona, Pennsylvania, USA.
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Źródło:
Environmental microbiology reports [Environ Microbiol Rep] 2023 Oct; Vol. 15 (5), pp. 422-425. Date of Electronic Publication: 2023 May 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Escherichia coli*/drug effects
Escherichia coli*/growth & development
Escherichia coli*/metabolism
Caffeine*/pharmacology
Oxygen/metabolism ; Gastrointestinal Microbiome/drug effects ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Eltoprazine modulated gamma oscillations on ameliorating L-dopa-induced dyskinesia in rats.
Autorzy:
Bi Y; Neurosurgery Center, Department of Pediatric Neurosurgery, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Wang P; Neurosurgery Center, Department of Pediatric Neurosurgery, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Yu J; Neurosurgery Center, Department of Pediatric Neurosurgery, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Wang Z; Neurosurgery Center, Department of Pediatric Neurosurgery, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Yang H; Neurosurgery Center, Department of Pediatric Neurosurgery, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Deng Y; Neurosurgery Center, Department of Pediatric Neurosurgery, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Guan J; Neurosurgery Center, Department of Pediatric Neurosurgery, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Zhang W; Neurosurgery Center, Department of Pediatric Neurosurgery, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2023 Oct; Vol. 29 (10), pp. 2998-3013. Date of Electronic Publication: 2023 Apr 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Serotonin Receptor Agonists*/pharmacology
Serotonin Receptor Agonists*/therapeutic use
Piperazines*/pharmacology
Piperazines*/therapeutic use
Gamma Rhythm*/drug effects
Levodopa*/adverse effects
Dyskinesia, Drug-Induced*/drug therapy
Antiparkinson Agents*/adverse effects
Animals ; Rats ; Disease Models, Animal ; Motor Cortex/drug effects ; Motor Cortex/physiopathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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