Temat: "element-binding protein" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Unlocking the Transcriptional Control of NCAPG in Bovine Myoblasts: CREB1 and MYOD1 as Key Players.
Autorzy:: Chen Z; Gansu Key Laboratory of Herbivorous Animal Biotechnology, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Li J; Gansu Key Laboratory of Herbivorous Animal Biotechnology, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Bai Y; Gansu Key Laboratory of Herbivorous Animal Biotechnology, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Liu Z; Gansu Key Laboratory of Herbivorous Animal Biotechnology, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Wei Y; Gansu Key Laboratory of Herbivorous Animal Biotechnology, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Guo D; Gansu Key Laboratory of Herbivorous Animal Biotechnology, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Jia X; Gansu Key Laboratory of Herbivorous Animal Biotechnology, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Shi B; Gansu Key Laboratory of Herbivorous Animal Biotechnology, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Zhang X; Gansu Key Laboratory of Herbivorous Animal Biotechnology, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Zhao Z; Gansu Key Laboratory of Herbivorous Animal Biotechnology, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Hu J; Gansu Key Laboratory of Herbivorous Animal Biotechnology, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Han X; Gansu Key Laboratory of Herbivorous Animal Biotechnology, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Wang J; Gansu Key Laboratory of Herbivorous Animal Biotechnology, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Liu X; Gansu Key Laboratory of Herbivorous Animal Biotechnology, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Li S; Gansu Key Laboratory of Herbivorous Animal Biotechnology, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Zhao F; Gansu Key Laboratory of Herbivorous Animal Biotechnology, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 21; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclic AMP Response Element-Binding Protein*/genetics
Gene Expression Regulation*
Cattle ; Animals ; Promoter Regions, Genetic ; Myoblasts

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Skocz do pozycji: 2.

Tytuł:: Adrenarche-accompanied rise of adrenal sex steroid precursors prevents NAFLD in Young Female rats by converting into active androgens and inactivating hepatic Srebf1 signaling.
Autorzy:: Li H; College of Life Science, Sichuan Agricultural University, Ya'an, 625014, China.
Liu Y; College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
Meng F; College of Life Science, Sichuan Agricultural University, Ya'an, 625014, China.
Chen J; College of Life Science, Sichuan Agricultural University, Ya'an, 625014, China.
Han X; College of Life Science, Sichuan Agricultural University, Ya'an, 625014, China. .; Pokaż więcej
Źródło:: BMC genomics [BMC Genomics] 2024 Feb 19; Vol. 25 (1), pp. 190. Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:: Journal Article
MeSH Terms:: Adrenarche*
Non-alcoholic Fatty Liver Disease*/etiology
Non-alcoholic Fatty Liver Disease*/prevention & control
Non-alcoholic Fatty Liver Disease*/metabolism
Sterol Regulatory Element Binding Protein 1*/metabolism
Animals ; Child ; Female ; Humans ; Rats ; Androgens ; Liver/metabolism ; Steroids

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Skocz do pozycji: 3.

Tytuł:: Characterization of the fatty acid binding protein 3 (FABP3) promoter and its transcriptional regulation by cAMP response element binding protein 1 (CREB1) in goat mammary epithelial cells.
Autorzy:: Yao D; Tianjin Institute of Animal Husbandry and Veterinary Medicine, Tianjin Academy of Agricultural Sciences, Tianjin, China.
Zhao X; Tianjin Institute of Animal Husbandry and Veterinary Medicine, Tianjin Academy of Agricultural Sciences, Tianjin, China.; College of Life Science, Nankai University, Tianjin, China.
Zhao S; Tianjin Institute of Animal Husbandry and Veterinary Medicine, Tianjin Academy of Agricultural Sciences, Tianjin, China.; College of Animal Science and Animal Medicine, Tianjin Agricultural University, Tianjin, China.
Shi H; College of Animal Science, Zhejiang University, Hangzhou, China.
Ma Y; Tianjin Institute of Animal Husbandry and Veterinary Medicine, Tianjin Academy of Agricultural Sciences, Tianjin, China.
Li J; College of Animal Science and Technology, Henan University of Animal Husbandry and Economy, Zhengzhou, China.; Pokaż więcej
Źródło:: Animal biotechnology [Anim Biotechnol] 2023 Nov; Vol. 34 (6), pp. 1960-1967. Date of Electronic Publication: 2022 Apr 13.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclic AMP Response Element-Binding Protein*/genetics
Cyclic AMP Response Element-Binding Protein*/metabolism
Goats*/genetics
Goats*/metabolism
Animals ; Fatty Acid Binding Protein 3/genetics ; Fatty Acid Binding Protein 3/metabolism ; Promoter Regions, Genetic/genetics ; Epithelial Cells/metabolism

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Skocz do pozycji: 4.

Tytuł:: The Role of SCAP/SREBP as Central Regulators of Lipid Metabolism in Hepatic Steatosis.
Autorzy:: Chandrasekaran P; UT Southwestern Medical Center Dallas, 5323 Harry Hines Blvd., Dallas, TX 75390, USA.
Weiskirchen R; Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry (IFMPEGKC), Rheinisch-Westfälische Technische Hochschule (RWTH) University Hospital Aachen, D-52074 Aachen, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 16; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 16.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Fatty Liver*
Liver Neoplasms*
Sterol Regulatory Element Binding Protein 1*/genetics
Intracellular Signaling Peptides and Proteins*/genetics
Membrane Proteins*/genetics
Animals ; Humans ; Lipid Metabolism ; Lipogenesis

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Skocz do pozycji: 5.

Tytuł:: The Dual Roles of Activating Transcription Factor 3 (ATF3) in Inflammation, Apoptosis, Ferroptosis, and Pathogen Infection Responses.
Autorzy:: Liu S; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730000, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou 730046, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou 730046, China.
Li Z; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730000, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou 730046, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou 730046, China.
Lan S; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730000, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou 730046, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou 730046, China.
Hao H; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730000, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou 730046, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou 730046, China.
Baz AA; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730000, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou 730046, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou 730046, China.
Yan X; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730000, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou 730046, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou 730046, China.
Gao P; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730000, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou 730046, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou 730046, China.
Chen S; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730000, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou 730046, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou 730046, China.
Chu Y; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730000, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou 730046, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou 730046, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 09; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 09.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Activating Transcription Factor 3*/genetics
Apoptosis*
Cyclic AMP Response Element-Binding Protein*
Ferroptosis*
Humans ; Inflammation

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Skocz do pozycji: 6.

Tytuł:: CREB Is Indispensable to KIT Function in Human Skin Mast Cells-A Positive Feedback Loop between CREB and KIT Orchestrates Skin Mast Cell Fate.
Autorzy:: Bal G; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology IA, 12203 Berlin, Germany.; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.
Schneikert J; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology IA, 12203 Berlin, Germany.; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.
Li Z; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology IA, 12203 Berlin, Germany.; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.
Franke K; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology IA, 12203 Berlin, Germany.; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.
Tripathi SR; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology IA, 12203 Berlin, Germany.; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.
Zuberbier T; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology IA, 12203 Berlin, Germany.; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.
Babina M; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology IA, 12203 Berlin, Germany.; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Dec 24; Vol. 13 (1). Date of Electronic Publication: 2023 Dec 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cyclic AMP Response Element-Binding Protein*
Mast Cells*
Humans ; Cell Differentiation ; Feedback ; Skin

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Skocz do pozycji: 7.

Tytuł:: Osthole Increases the Sensitivity of Liver Cancer to Sorafenib by Inhibiting Cholesterol Metabolism.
Autorzy:: Fan K; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu Province, China.
Huang H; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu Province, China.
Zhao Y; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu Province, China.; Department of Pharmacy, Children's Hospital of Soochow University, Suzhou, Jiangsu Province, China.
Xie T; Department of Neurosurgery, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, Jiangsu Province, China.
Zhu ZY; Department of Pharmacy, Children's Hospital of Soochow University, Suzhou, Jiangsu Province, China.
Xie ML; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu Province, China.; Pokaż więcej
Źródło:: Nutrition and cancer [Nutr Cancer] 2022; Vol. 74 (10), pp. 3640-3650. Date of Electronic Publication: 2022 Jun 15.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Liver Neoplasms*/pathology
Sterol Regulatory Element Binding Protein 2*/genetics
Sterol Regulatory Element Binding Protein 2*/metabolism
Animals ; Cholesterol/metabolism ; Coumarins ; Liver/metabolism ; Mice ; Sorafenib/pharmacology ; Sterol Regulatory Element Binding Protein 1/metabolism

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Skocz do pozycji: 8.

Tytuł:: Excess phosphate promotes SARS‑CoV‑2 N protein‑induced NLRP3 inflammasome activation via the SCAP‑SREBP2 signaling pathway.
Autorzy:: Liu MH; Department of Clinical Laboratory, The Affiliated Ganzhou Hospital of Nanchang University, Ganzhou, Jiangxi 341000, P.R. China.
Lin XL; Department of Pathology, Huizhou Third People's Hospital, Guangzhou Medical University, Huizhou, Guangdong 516002, P.R. China.
Xiao LL; Department of Nursing, The Affiliated Ganzhou Hospital of Nanchang University, Ganzhou, Jiangxi 341000, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2024 Mar; Vol. 29 (3). Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:: Journal Article
MeSH Terms:: Hyperphosphatemia*
COVID-19*
Membrane Proteins*
Intracellular Signaling Peptides and Proteins*
Humans ; Inflammasomes/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Proprotein Convertase 9/metabolism ; Sterol Regulatory Element Binding Protein 2/genetics ; Sterol Regulatory Element Binding Protein 2/metabolism ; SARS-CoV-2/metabolism ; Phosphates ; Sterol Regulatory Element Binding Protein 1/metabolism ; Signal Transduction ; Inflammation

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Skocz do pozycji: 9.

Tytuł:: A short peptide LINC00665_18aa encoded by lncRNA LINC00665 suppresses the proliferation and migration of osteosarcoma cells through the regulation of the CREB1/RPS6KA3 interaction.
Autorzy:: Pan J; Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Liu M; Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Duan X; Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Wang D; Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Jun 07; Vol. 18 (6), pp. e0286422. Date of Electronic Publication: 2023 Jun 07 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Osteosarcoma*/metabolism
Osteosarcoma*/pathology
RNA, Long Noncoding*
Cyclic AMP Response Element-Binding Protein*/metabolism
Ribosomal Protein S6 Kinases, 90-kDa*/metabolism
Peptides*/metabolism
Humans ; Cell Line ; Animals ; Mice ; Heterografts ; Neoplasm Transplantation ; Cell Proliferation ; Cell Movement ; Cell Line, Tumor ; Bone Neoplasms/metabolism ; Bone Neoplasms/pathology

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Skocz do pozycji: 10.

Tytuł:: Hepatic glycogenesis antagonizes lipogenesis by blocking S1P via UDPG.
Autorzy:: Chen J; Department of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.
Zhou Y; Department of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.
Liu Z; Department of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.
Lu Y; Department of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.
Jiang Y; Department of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.
Cao K; Department of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.
Zhou N; Department of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.
Wang D; Department of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.
Zhang C; Department of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.; Department of Thoracic Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Zhou N; Department of Pathology, Sichuan Mianyang 404 Hospital, Sichuan 621000, China.
Shi K; Translational Medicine Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325035, China.
Zhang L; Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China.
Zhou L; Department of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.
Wang Z; Department of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.
Zhang H; Department of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Tang K; Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Ma J; Department of Immunology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Lv J; Department of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.
Huang B; Department of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.; Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2024 Feb 16; Vol. 383 (6684), pp. eadi3332. Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:: Journal Article
MeSH Terms:: Lipogenesis*
Liver*/metabolism
Liver Glycogen*/metabolism
Non-alcoholic Fatty Liver Disease*/drug therapy
Non-alcoholic Fatty Liver Disease*/metabolism
Proprotein Convertases*/metabolism
Serine Endopeptidases*
Uridine Diphosphate Glucose*/administration & dosage
Uridine Diphosphate Glucose*/metabolism
Animals ; Humans ; Mice ; Carbon/metabolism ; Glucose/metabolism ; Hepatocytes/metabolism ; Sterol Regulatory Element Binding Protein 1/genetics ; Sterol Regulatory Element Binding Protein 1/metabolism ; Male ; Mice, Inbred C57BL ; HEK293 Cells

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Skocz do pozycji: 11.

Tytuł:: Laminaria japonica Aresch-Derived Fucoidan Ameliorates Hyperlipidemia by Upregulating LXRs and Suppressing SREBPs.
Autorzy:: Zhang Y; Department of Endocrinology and Metabolism, Guiqian International General Hospital, Guiyang 550018, China.
Liu T; Institute of Lipid Metabolism and Atherosclerosis, Innovative Drug Research Centre, School of Pharmacy, Weifang Medical University, Weifang 261053, China.
Qu ZJ; Cardiology Department, Qingzhou People's Hospital, Weifang 262500, China.
Wang X; Institute of Lipid Metabolism and Atherosclerosis, Innovative Drug Research Centre, School of Pharmacy, Weifang Medical University, Weifang 261053, China.
Song WG; Shandong Provincial Key Laboratory for Rheumatic Disease and Translational Medicine, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan 250014, China.
Guo SD; Institute of Lipid Metabolism and Atherosclerosis, Innovative Drug Research Centre, School of Pharmacy, Weifang Medical University, Weifang 261053, China.; Pokaż więcej
Źródło:: Cardiovascular therapeutics [Cardiovasc Ther] 2024 Feb 12; Vol. 2024, pp. 8649365. Date of Electronic Publication: 2024 Feb 12 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Hyperlipidemias*/drug therapy
Hyperlipidemias*/genetics
Hyperlipidemias*/metabolism
Cardiovascular Diseases*/metabolism
Edible Seaweeds*
Laminaria*
Polysaccharides*
Mice ; Animals ; Proprotein Convertase 9/metabolism ; Sterol Regulatory Element Binding Protein 1/metabolism ; Sterol Regulatory Element Binding Protein 1/pharmacology ; Mice, Inbred C57BL ; Liver ; Cholesterol/metabolism ; Cholesterol/pharmacology ; Lipids
SCR Organism:: kombu kelp

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Skocz do pozycji: 12.

Tytuł:: Drynaria rhizome water extract alleviates high‑fat diet‑induced obesity in mice.
Autorzy:: Gil TY; Department of Oriental Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea.
Park J; Department of Science in Korean Medicine, College of Korean Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Park YJ; Department of Oriental Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea.
Kim HJ; Department of Oriental Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea.
Cominguez DC; Department of Rehabilitative Medicine of Korean Medicine and Neuropsychiatry, College of Korean Medicine, Sangji University, Wonju, Gangwon 26339, Republic of Korea.
An HJ; Department of Oriental Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2024 Feb; Vol. 29 (2). Date of Electronic Publication: 2023 Dec 22.
Typ publikacji:: Journal Article
MeSH Terms:: Diet, High-Fat*/adverse effects
Anti-Obesity Agents*/pharmacology
Mice ; Animals ; Sterol Regulatory Element Binding Protein 1/genetics ; Sterol Regulatory Element Binding Protein 1/metabolism ; AMP-Activated Protein Kinases/metabolism ; Peroxisome Proliferator-Activated Receptors ; Rhizome ; Plant Extracts/pharmacology ; Obesity/drug therapy ; Obesity/etiology ; Obesity/metabolism ; Body Weight ; Mice, Inbred C57BL ; Mice, Obese

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Skocz do pozycji: 13.

Tytuł:: Plasma microRNA-320c as a Potential Biomarker for the Severity of Knee Osteoarthritis and Regulates cAMP Responsive Element Binding Protein 5 (CREB5) in Chondrocytes.
Autorzy:: Zhou R; Department of Respiratory and Critical Care Medicine, School of Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200233, China.
Zhao L; Department of Rheumatology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.
Wang Q; Department of Rheumatology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.
Cheng Y; Department of Rheumatology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.
Song M; Department of Emergency Medicine, Shanghai Eighth People's Hospital, Shanghai 200235, China.
Huang C; Department of Rheumatology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.; Pokaż więcej
Źródło:: Disease markers [Dis Markers] 2024 Mar 20; Vol. 2024, pp. 9936295. Date of Electronic Publication: 2024 Mar 20 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: MicroRNAs*/genetics
MicroRNAs*/metabolism
Osteoarthritis, Knee*/genetics
Osteoarthritis, Knee*/metabolism
Humans ; Chondrocytes/metabolism ; Biomarkers/metabolism ; Luciferases/metabolism ; Interleukin-1beta/metabolism ; Cyclic AMP Response Element-Binding Protein A/metabolism

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Skocz do pozycji: 14.

Tytuł:: Identification of SLC40A1, LCN2, CREB5, and SLC7A11 as ferroptosis-related biomarkers in alopecia areata through machine learning.
Autorzy:: Xu W; School of Medicine, Zhejiang University, Hangzhou, 310009, China.; Department of Dermatology, Hangzhou Third People's Hospital, Affiliated Hangzhou Dermatology Hospital, Zhejiang University School of Medicine, West Lake Ave 38, Hangzhou, 310009, China.
Wei D; School of Medicine, Zhejiang University, Hangzhou, 310009, China.; Department of Dermatology, Hangzhou Third People's Hospital, Affiliated Hangzhou Dermatology Hospital, Zhejiang University School of Medicine, West Lake Ave 38, Hangzhou, 310009, China.
Song X; Department of Dermatology, Hangzhou Third People's Hospital, Affiliated Hangzhou Dermatology Hospital, Zhejiang University School of Medicine, West Lake Ave 38, Hangzhou, 310009, China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 15; Vol. 14 (1), pp. 3800. Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:: Journal Article
MeSH Terms:: Alopecia Areata*/genetics
Ferroptosis*/genetics
Humans ; Amino Acid Transport System y+/genetics ; Cyclic AMP Response Element-Binding Protein A ; Lipocalin-2 ; Machine Learning ; Genetic Markers
SCR Disease Name:: Diffuse alopecia

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Skocz do pozycji: 15.

Tytuł:: KIF26B and CREB3L1 Derived from Immunoscore Could Inhibit the Progression of Ovarian Cancer.
Autorzy:: Cong S; Department of Gynecology, Affiliated Women's Hospital of Jiangnan University, Wuxi, China.
Fu Y; Department of Pharmacy, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Zhao X; Department of Gynecology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Guo Q; Department of Gynecology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Liang T; Department of Gynecology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Wu D; Department of Gynecology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Wang J; Department of Gynecology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Zhang G; Department of Gynecology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.; Pokaż więcej
Źródło:: Journal of immunology research [J Immunol Res] 2024 Feb 13; Vol. 2024, pp. 4817924. Date of Electronic Publication: 2024 Feb 13 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Ovarian Neoplasms*/genetics
Female ; Humans ; Extracellular Matrix ; Gene Regulatory Networks ; Immunotherapy ; Nerve Tissue Proteins ; Cyclic AMP Response Element-Binding Protein/genetics ; Kinesins/genetics

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Skocz do pozycji: 16.

Tytuł:: Novel Glycomimetics Protect against Glycated Low-Density Lipoprotein-Induced Vascular Calcification In Vitro via Attenuation of the RAGE/ERK/CREB Pathway.
Autorzy:: Sidgwick GP; Department of Life Sciences, Manchester Metropolitan University, Manchester M1 5GD, UK.
Weston R; Department of Life Sciences, Manchester Metropolitan University, Manchester M1 5GD, UK.
Mahmoud AM; Department of Life Sciences, Manchester Metropolitan University, Manchester M1 5GD, UK.
Schiro A; Cardiovascular Research Institute, University of Manchester, Manchester M13 9PL, UK.; Vascular Unit, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.
Serracino-Inglott F; Department of Life Sciences, Manchester Metropolitan University, Manchester M1 5GD, UK.; Cardiovascular Research Institute, University of Manchester, Manchester M13 9PL, UK.; Vascular Unit, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.
Tandel SM; Department of Life Sciences, Manchester Metropolitan University, Manchester M1 5GD, UK.
Skeoch S; Centre for Epidemiology Versus Arthritis, University of Manchester, Manchester M13 9PL, UK.; National Institute for Health Research Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9PL, UK.; Royal National Hospital for Rheumatic Diseases, Bath BA1 1RL, UK.
Bruce IN; Centre for Epidemiology Versus Arthritis, University of Manchester, Manchester M13 9PL, UK.; National Institute for Health Research Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9PL, UK.
Jones AM; Department of Life Sciences, Manchester Metropolitan University, Manchester M1 5GD, UK.; School of Pharmacy, University of Birmingham, Birmingham B15 2TT, UK.
Alexander MY; Department of Life Sciences, Manchester Metropolitan University, Manchester M1 5GD, UK.
Wilkinson FL; Department of Life Sciences, Manchester Metropolitan University, Manchester M1 5GD, UK.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Feb 08; Vol. 13 (4). Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:: Journal Article
MeSH Terms:: Lipoproteins, LDL*/adverse effects
Vascular Calcification*/metabolism
Humans ; Cyclic AMP Response Element-Binding Protein ; Molecular Docking Simulation ; Cells, Cultured

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Skocz do pozycji: 17.

Tytuł:: A study of roflumilast treatment on functional and structural changes in hippocampus in depressed Adult male Wistar rats.
Autorzy:: Hassan G; Medical Physiology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Kamar SA; Anatomy Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.; Faculty of Dentistry, Al-Ahliyya Amman University, Amman, Jordan.
Rady HY; Anatomy Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.; Anatomy Department, Armed Forces College of Medicine, Cairo, Egypt.
Abdelrahim DS; Clinical Pharmacology department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.; Pharmacology Department, Faculty of Medicine, Modern University for Technology and Information, Cairo, Egypt.
Abdel Hay Ibrahim NH; Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Lasheen NN; Medical Physiology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.; Associate Professor of Physiology, Faculty of Medicine, Galala University, Suez, Egypt.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Feb 05; Vol. 19 (2), pp. e0296187. Date of Electronic Publication: 2024 Feb 05 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Phosphodiesterase 4 Inhibitors*/pharmacology
Phosphodiesterase 4 Inhibitors*/therapeutic use
Phosphodiesterase 4 Inhibitors*/metabolism
Neurodegenerative Diseases*/metabolism
Aminopyridines*
Benzamides*
Rats ; Male ; Animals ; Rats, Wistar ; Brain-Derived Neurotrophic Factor/metabolism ; Hippocampus/metabolism ; Cyclic AMP Response Element-Binding Protein/metabolism ; Cyclopropanes

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Skocz do pozycji: 18.

Tytuł:: The blockade of the TGF-β pathway alleviates abnormal glucose and lipid metabolism of lipodystrophy not obesity.
Autorzy:: Xu WD; Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education of China, Guangdong Pharmaceutical University, Guangzhou, China.; Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong TCM Key Laboratory for Metabolic Diseases, Guangdong Pharmaceutical University, Guangzhou, China.
Lai SZ; Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education of China, Guangdong Pharmaceutical University, Guangzhou, China.; Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong TCM Key Laboratory for Metabolic Diseases, Guangdong Pharmaceutical University, Guangzhou, China.
Zhao J; Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education of China, Guangdong Pharmaceutical University, Guangzhou, China.; Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong TCM Key Laboratory for Metabolic Diseases, Guangdong Pharmaceutical University, Guangzhou, China.
Wei SJ; Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education of China, Guangdong Pharmaceutical University, Guangzhou, China.; Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong TCM Key Laboratory for Metabolic Diseases, Guangdong Pharmaceutical University, Guangzhou, China.
Fang XY; Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education of China, Guangdong Pharmaceutical University, Guangzhou, China.; Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong TCM Key Laboratory for Metabolic Diseases, Guangdong Pharmaceutical University, Guangzhou, China.
Liu YY; Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education of China, Guangdong Pharmaceutical University, Guangzhou, China.; Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong TCM Key Laboratory for Metabolic Diseases, Guangdong Pharmaceutical University, Guangzhou, China.
Rong XL; Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education of China, Guangdong Pharmaceutical University, Guangzhou, China.; Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong TCM Key Laboratory for Metabolic Diseases, Guangdong Pharmaceutical University, Guangzhou, China.
Guo J; Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education of China, Guangdong Pharmaceutical University, Guangzhou, China.; Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong TCM Key Laboratory for Metabolic Diseases, Guangdong Pharmaceutical University, Guangzhou, China.; Pokaż więcej
Źródło:: Pharmacology research & perspectives [Pharmacol Res Perspect] 2024 Feb; Vol. 12 (1), pp. e1160.
Typ publikacji:: Journal Article
MeSH Terms:: Lipid Metabolism*
Lipodystrophy*/drug therapy
Mice ; Animals ; Transforming Growth Factor beta/metabolism ; Sterol Regulatory Element Binding Protein 1/metabolism ; Glycerol ; Obesity/drug therapy ; Obesity/metabolism ; Glucose/metabolism

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Skocz do pozycji: 19.

Tytuł:: Up-regulation of CREB-1 regulates tendon adhesion in the injury tendon healing through the CREB-1/TGF-β3 signaling pathway.
Autorzy:: Wu LM; Department of Orthopaedics, Daping Hospital, Army Medical University, 10 Changjiang Branch Road, Yuzhong District, Chongqing, 400042, People's Republic of China.; Department of Orthopaedics, Chongqing Public Health Medical Center, Chongqing, 400030, People's Republic of China.
Wang YJ; Department of Sports Medicine Center, State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Army Medical University, Chongqing, 400038, People's Republic of China.
Li SF; Department of Spinal Surgery, the General Hospital of the People's Liberation Army Tibet Military Area Command, Lhasa, 850007, People's Republic of China.
Wang JK; Department of Orthopaedics, Daping Hospital, Army Medical University, 10 Changjiang Branch Road, Yuzhong District, Chongqing, 400042, People's Republic of China.
Liu J; Department of Orthopaedics, Daping Hospital, Army Medical University, 10 Changjiang Branch Road, Yuzhong District, Chongqing, 400042, People's Republic of China.
Fan CC; Department of Orthopaedics, the People's Hospital of Nanchuan, Chongqing, 408400, People's Republic of China.
Xiong Y; Department of Orthopaedics, Daping Hospital, Army Medical University, 10 Changjiang Branch Road, Yuzhong District, Chongqing, 400042, People's Republic of China. .; Pokaż więcej
Źródło:: BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2023 Apr 25; Vol. 24 (1), pp. 325. Date of Electronic Publication: 2023 Apr 25.
Typ publikacji:: Journal Article
MeSH Terms:: Tendon Injuries*/metabolism
Cyclic AMP Response Element-Binding Protein*/metabolism
Wound Healing*
Transforming Growth Factor beta3*/metabolism
Animals ; Mice ; Tendons ; Signal Transduction ; Mice, Inbred C57BL ; Male ; Stem Cells ; Gait Analysis ; Tissue Adhesions/prevention & control

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Skocz do pozycji: 20.

Tytuł:: Activation of transcription factor CREB in human macrophages by Mycobacterium tuberculosis promotes bacterial survival, reduces NF-kB nuclear transit and limits phagolysosome fusion by reduced necroptotic signaling.
Autorzy:: Leopold Wager CM; Host Pathogen Interaction Program, Texas Biomedical Research Institute, San Antonio, Texas, United States of America.
Bonifacio JR; Host Pathogen Interaction Program, Texas Biomedical Research Institute, San Antonio, Texas, United States of America.
Simper J; Host Pathogen Interaction Program, Texas Biomedical Research Institute, San Antonio, Texas, United States of America.; Medical Scientist Training Program, Department of Microbiology, Immunology and Molecular Genetics, UT Health Science Center San Antonio, San Antonio, Texas, United States of America.
Naoun AA; Department of Biology, The University of Texas at San Antonio, San Antonio, Texas, United States of America.
Arnett E; Host Pathogen Interaction Program, Texas Biomedical Research Institute, San Antonio, Texas, United States of America.
Schlesinger LS; Host Pathogen Interaction Program, Texas Biomedical Research Institute, San Antonio, Texas, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2023 Mar 31; Vol. 19 (3), pp. e1011297. Date of Electronic Publication: 2023 Mar 31 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Cyclic AMP Response Element-Binding Protein*/metabolism
Macrophages*/metabolism
Mycobacterium tuberculosis*/genetics
Tuberculosis*/metabolism
Tuberculosis*/microbiology
Humans ; Necroptosis ; NF-kappa B/metabolism ; Phagosomes/metabolism ; Signal Transduction

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