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Wyszukujesz frazę ""endothelin receptors"" wg kryterium: Temat


Tytuł:
Preclinical metabolism and the disposition of vornorexant/TS‐142, a novel dual orexin 1/2 receptor antagonist for the treatment of insomnia.
Autorzy:
Konno, Yoshihiro (AUTHOR) y‐
Kamigaso, Shunsuke (AUTHOR)
Toki, Hidetoh (AUTHOR)
Terasaka, Shuichi (AUTHOR)
Hikichi, Hirohiko (AUTHOR)
Endo, Hiromi (AUTHOR)
Yamaguchi, Jun‐Ichi (AUTHOR)
Mizuno‐Yasuhira, Akiko (AUTHOR)
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Źródło:
Pharmacology Research & Perspectives. Apr2024, Vol. 12 Issue 2, p1-14. 14p.
Czasopismo naukowe
Tytuł:
Autoantibodies Targeting G-Protein-Coupled Receptors: Pathogenetic, Clinical and Therapeutic Implications in Systemic Sclerosis.
Autorzy:
Binda, Marco (AUTHOR)
Moccaldi, Beatrice (AUTHOR)
Civieri, Giovanni (AUTHOR)
Cuberli, Anna (AUTHOR)
Doria, Andrea (AUTHOR)
Tona, Francesco (AUTHOR)
Zanatta, Elisabetta (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Feb2024, Vol. 25 Issue 4, p2299. 17p.
Czasopismo naukowe
Tytuł:
Comparative Treatment Persistence and Adherence to Endothelin Receptor Antagonists Among Patients with Pulmonary Arterial Hypertension in Japan: A Real-World Administrative Claims Database Study.
Autorzy:
Omura, Junichi (AUTHOR)
Makanji, Yogeshwar (AUTHOR)
Tanabe, Nobuhiro (AUTHOR)
Yu, Dae Young (AUTHOR)
Tan, Jin Yu (AUTHOR)
Lim, Sooyeol (AUTHOR)
Kouhkamari, Mahsa H. (AUTHOR)
Casorso, Jeremy (AUTHOR)
Wu, David Bin-Chia (AUTHOR)
Bloomfield, Paul (AUTHOR)
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Źródło:
Pulmonary Therapy. Dec2023, Vol. 9 Issue 4, p511-526. 16p.
Czasopismo naukowe
Tytuł:
Plasma untargeted metabolomics with proteinase K discloses phospholipid signature associated with pulmonary arterial hypertension.
Autorzy:
Wawrzyniak, Renata (AUTHOR)
Biesemans, Margot (AUTHOR)
Kugacka-Dąbrowska, Alicja (AUTHOR)
Lewicka, Ewa (AUTHOR)
Bartoszewski, Rafał (AUTHOR)
Markuszewski, Michał J. (AUTHOR)
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Źródło:
Scientific Reports. 11/18/2023, Vol. 13 Issue 1, p1-11. 11p.
Czasopismo naukowe
Tytuł:
Insulin resistance, kidney outcomes and effects of the endothelin receptor antagonist atrasentan in patients with type 2 diabetes and chronic kidney disease.
Autorzy:
Smeijer, J. David (AUTHOR)
Kohan, Donald E. (AUTHOR)
Rossing, Peter (AUTHOR)
Correa-Rotter, Ricardo (AUTHOR)
Liew, Adrian (AUTHOR)
Tang, Sydney C.W. (AUTHOR)
de Zeeuw, Dick (AUTHOR)
Gansevoort, Ron T. (AUTHOR)
Ju, Wenjun (AUTHOR)
Lambers Heerspink, Hiddo J. (AUTHOR)
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Źródło:
Cardiovascular Diabetology. 9/16/2023, Vol. 22 Issue 1, p1-9. 9p.
Czasopismo naukowe
Tytuł:
Study of fingolimod, nitric oxide inhibitor, and P-glycoprotein inhibitor in modulating the P-glycoprotein expression via an endothelin-sphingolipid pathway in an animal model of pharmacoresistant epilepsy.
Autorzy:
Garg, Nitika
Joshi, Rupa
Bhatia, Alka
Bansal, Seema
Chakrabarti, Amitava
Prakash, Ajay
Saikia, Biman
Modi, Manish
Medhi, Bikash
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Źródło:
Indian Journal of Pharmacology. Sep/Oct2023, Vol. 55 Issue 5, p307-314. 8p.
Czasopismo naukowe
Tytuł:
Effects of Angiotensin 1-7 and Mas Receptor Agonist on Renal System in a Rat Model of Heart Failure.
Autorzy:
Cohen-Segev, Ravit (AUTHOR)
Nativ, Omri (AUTHOR)
Kinaneh, Safa (AUTHOR)
Aronson, Doron (AUTHOR)
Kabala, Aviva (AUTHOR)
Hamoud, Shadi (AUTHOR)
Karram, Tony (AUTHOR)
Abassi, Zaid (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Jul2023, Vol. 24 Issue 14, p11470. 19p.
Czasopismo naukowe
Tytuł:
Pharmacological Characterization of P626, a Novel Dual Adenosine A 2A /A 2B Receptor Antagonist, on Synaptic Plasticity and during an Ischemic-like Insult in CA1 Rat Hippocampus.
Autorzy:
Venturini, Martina (AUTHOR)
Cherchi, Federica (AUTHOR)
Santalmasi, Clara (AUTHOR)
Frulloni, Lucia (AUTHOR)
Dettori, Ilaria (AUTHOR)
Catarzi, Daniela (AUTHOR)
Pedata, Felicita (AUTHOR)
Colotta, Vittoria (AUTHOR)
Varano, Flavia (AUTHOR)
Coppi, Elisabetta (AUTHOR)
Pugliese, Anna Maria (AUTHOR)
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Źródło:
Biomolecules (2218-273X). Jun2023, Vol. 13 Issue 6, p894. 14p.
Czasopismo naukowe
Tytuł:
Non-Haemodynamic Mechanisms Underlying Hypertension-Associated Damage in Target Kidney Components.
Autorzy:
Russo, Elisa (AUTHOR)
Bussalino, Elisabetta (AUTHOR)
Macciò, Lucia (AUTHOR)
Verzola, Daniela (AUTHOR)
Saio, Michela (AUTHOR)
Esposito, Pasquale (AUTHOR)
Leoncini, Giovanna (AUTHOR)
Pontremoli, Roberto (AUTHOR)
Viazzi, Francesca (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Jun2023, Vol. 24 Issue 11, p9422. 15p.
Czasopismo naukowe
Tytuł:
Validation of Freshly Isolated Rat Renal Cells as a Tool for Preclinical Assessment of Radiolabeled Receptor-Specific Peptide Uptake in the Kidney.
Autorzy:
Barta, Pavel (AUTHOR)
Nachtigal, Petr (AUTHOR)
Maixnerova, Jana (AUTHOR)
Zemankova, Lenka (AUTHOR)
Trejtnar, Frantisek (AUTHOR)
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Źródło:
Pharmaceuticals (14248247). May2023, Vol. 16 Issue 5, p696. 14p.
Czasopismo naukowe
Tytuł:
Dual Blockade of TGF-β Receptor and Endothelin Receptor Synergistically Inhibits Angiotensin II-Induced Myofibroblast Differentiation: Role of AT 1 R/G αq -Mediated TGF-β1 and ET-1 Signaling.
Autorzy:
Duangrat, Ratchanee (AUTHOR)
Parichatikanond, Warisara (AUTHOR)
Mangmool, Supachoke (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Apr2023, Vol. 24 Issue 8, p6972. 16p.
Czasopismo naukowe
Tytuł:
Single-dose pharmacokinetics, safety, and tolerability of the dual endothelin receptor antagonist aprocitentan in subjects with moderate hepatic impairment.
Autorzy:
Fontes, Magda S. C. (AUTHOR)
Dingemanse, Jasper (AUTHOR)
Halabi, Atef (AUTHOR)
Tomaszewska-Kiecana, Monika (AUTHOR)
Sidharta, Patricia N. (AUTHOR)
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Źródło:
Scientific Reports. 11/9/2022, Vol. 12 Issue 1, p1-7. 7p.
Czasopismo naukowe
Tytuł:
Chromosome-level genome and population genomics reveal evolutionary characteristics and conservation status of Chinese indigenous geese.
Autorzy:
Ouyang, Jing (AUTHOR)
Zheng, Sumei (AUTHOR)
Huang, Min (AUTHOR)
Tang, Hongbo (AUTHOR)
Qiu, Xiaohui (AUTHOR)
Chen, Shoujin (AUTHOR)
Wang, Zhangzhang (AUTHOR)
Zhou, Zhongdong (AUTHOR)
Gao, Yuren (AUTHOR)
Xiong, Yanpeng (AUTHOR)
Zeng, Guohua (AUTHOR)
Huang, Jimin (AUTHOR)
He, Jiugen (AUTHOR)
Ren, Jun (AUTHOR)
Chen, Hao (AUTHOR)
Yan, Xueming (AUTHOR)
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Źródło:
Communications Biology. 11/7/2022, Vol. 5 Issue 1, p1-12. 12p.
Czasopismo naukowe
Tytuł:
Enhanced Cardiorenal Protective Effects of Combining SGLT2 Inhibition, Endothelin Receptor Antagonism and RAS Blockade in Type 2 Diabetic Mice.
Autorzy:
Vergara, Ander (AUTHOR)
Jacobs-Cacha, Conxita (AUTHOR)
Llorens-Cebria, Carmen (AUTHOR)
Ortiz, Alberto (AUTHOR)
Martinez-Diaz, Irene (AUTHOR)
Martos, Nerea (AUTHOR)
Dominguez-Báez, Pamela (AUTHOR)
Van den Bosch, Mireia Molina (AUTHOR)
Bermejo, Sheila (AUTHOR)
Pieper, Michael Paul (AUTHOR)
Benito, Begoña (AUTHOR)
Soler, Maria Jose (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Nov2022, Vol. 23 Issue 21, p12823. 23p.
Czasopismo naukowe
Tytuł:
Treatment of nonarteritic anterior ischemic optic neuropathy with an endothelin antagonist: ENDOTHELION (ENDOTHELin antagonist receptor in Ischemic Optic Neuropathy)-a multicentre randomised controlled trial protocol.
Autorzy:
Chiquet, Christophe (AUTHOR)
Vignal, Catherine (AUTHOR)
Gohier, Philippe (AUTHOR)
Heron, Emmanuel (AUTHOR)
Thuret, Gilles (AUTHOR)
Rougier, Marie Bénédicte (AUTHOR)
Lehmann, Audrey (AUTHOR)
Flet, Laurent (AUTHOR)
Quesada, Jean-Louis (AUTHOR)
Roustit, Mathieu (AUTHOR)
Milea, Dan (AUTHOR)
Pepin, Jean-Louis (AUTHOR)
ENDOTHELION group (CORPORATE AUTHOR)
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Źródło:
Trials. 10/29/2022, Vol. 23 Issue 1, p1-24. 24p. 1 Diagram, 7 Charts.
Czasopismo naukowe
Tytuł:
Safety of macitentan for the treatment of pulmonary hypertension: Real-world experience from the OPsumit® USers Registry (OPUS) and OPsumit® Historical USers cohort (OrPHeUS).
Autorzy:
McLaughlin, Vallerie V.
Channick, Richard
Kim, Nick H.
Frantz, Robert P.
McConnell, John W.
Melendres-Groves, Lana
Miller, Chad
Ravichandra, Ashwin
Rodriguez-Lopez, Josanna
Brand, Monika
Leroy, Sandrine
Wetherill, Graham
Chin, Kelly M.
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Źródło:
Pulmonary Circulation. Oct2022, Vol. 12 Issue 4, p1-18. 15p.
Czasopismo naukowe
Tytuł:
Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR and a middle sized flexible molecule.
Autorzy:
Higo, Junichi (AUTHOR)
Kasahara, Kota (AUTHOR)
Bekker, Gert-Jan (AUTHOR)
Ma, Benson (AUTHOR)
Sakuraba, Shun (AUTHOR)
Iida, Shinji (AUTHOR)
Kamiya, Narutoshi (AUTHOR)
Fukuda, Ikuo (AUTHOR)
Kono, Hidetoshi (AUTHOR)
Fukunishi, Yoshifumi (AUTHOR)
Nakamura, Haruki (AUTHOR)
Pokaż więcej
Źródło:
Scientific Reports. 8/13/2022, Vol. 12 Issue 1, p1-19. 19p.
Czasopismo naukowe
Tytuł:
Lack of renoprotective effects of targeting the endothelin A receptor and (or) sodium glucose transporter 2 in a mouse model of Type 2 diabetic kidney disease.
Autorzy:
Stuart, Deborah
Peterson, Caitlin S.
Hu, Chunyan
Revelo, Monica P.
Huang, Yufeng
Kohan, Donald E.
Ramkumar, Nirupama
Pokaż więcej
Źródło:
Canadian Journal of Physiology & Pharmacology. 2022, Vol. 100 Issue 8, p763-771. 9p.
Czasopismo naukowe
Tytuł:
Pharmacokinetics and Tolerability of Zibotentan in Patients with Concurrent Moderate Renal and Moderate Hepatic Impairment.
Autorzy:
Mercier, Anne-Kristina (AUTHOR)
Sunnåker, Mikael (AUTHOR)
Ueckert, Sebastian (AUTHOR)
Pawlik, Tadeusz (AUTHOR)
Henricson, Emilia (AUTHOR)
Molodetskyi, Oleksandr (AUTHOR)
Law, Gordon C. (AUTHOR)
Parker, Victoria E. R. (AUTHOR)
Oscarsson, Jan (AUTHOR)
Pokaż więcej
Źródło:
Clinical Pharmacokinetics. Dec2023, Vol. 62 Issue 12, p1713-1724. 12p.
Czasopismo naukowe
Tytuł:
Chronic intermittent hypoxia, a hallmark of obstructive sleep apnea, promotes 4T1 breast cancer development through endothelin-1 receptors.
Autorzy:
Minoves, Mélanie (AUTHOR)
Kotzki, Sylvain (AUTHOR)
Hazane-Puch, Florence (AUTHOR)
Lemarié, Emeline (AUTHOR)
Bouyon, Sophie (AUTHOR)
Vollaire, Julien (AUTHOR)
Gonthier, Brigitte (AUTHOR)
Pépin, Jean-Louis (AUTHOR)
Josserand, Véronique (AUTHOR)
Briançon-Marjollet, Anne (AUTHOR)
Godin-Ribuot, Diane (AUTHOR)
Pokaż więcej
Źródło:
Scientific Reports. 7/28/2022, Vol. 12 Issue 1, p1-12. 12p.
Czasopismo naukowe
Tytuł:
Endothelins and α‐melanocyte‐stimulating hormone are increased in plasma of patients treated with UVA1 and psoralen plus UVA.
Autorzy:
Abdel‐Naser, M. Badawy (AUTHOR)
Seltmann, Holger (AUTHOR)
Altenburg, Andreas (AUTHOR)
Zouboulis, Christos C. (AUTHOR) christos.zouboulis@mhb‐fontane.de
Pokaż więcej
Źródło:
Photodermatology, Photoimmunology & Photomedicine. Nov2022, Vol. 38 Issue 6, p611-613. 3p.
Czasopismo naukowe
Tytuł:
Chalcone‐inspired rA1/A2A adenosine receptor ligands: Ring closure as an alternative to a reactive substructure.
Autorzy:
Matthee, Chrisna (AUTHOR)
Terre'Blanche, Gisella (AUTHOR)
Janse van Rensburg, Helena D. (AUTHOR)
Aucamp, Janine (AUTHOR)
Legoabe, Lesetja J. (AUTHOR)
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Źródło:
Chemical Biology & Drug Design. Mar2022, Vol. 99 Issue 3, p416-437. 22p.
Czasopismo naukowe
Tytuł:
ImmunoPET imaging–based pharmacokinetic profiles of an antibody and its Fab targeting endothelin A receptors on glioblastoma stem cells in a preclinical orthotopic model.
Autorzy:
Hautiere, Marie (AUTHOR)
Vivier, Delphine (AUTHOR)
Pineau, Donovan (AUTHOR)
Denis, Caroline (AUTHOR)
Kereselidze, Dimitri (AUTHOR)
Herbet, Amaury (AUTHOR)
Costa, Narciso (AUTHOR)
Goncalves, Victor (AUTHOR)
Selingue, Erwan (AUTHOR)
Larrat, Benoit (AUTHOR)
Hugnot, Jean Philippe (AUTHOR)
Denat, Franck (AUTHOR)
Boquet, Didier (AUTHOR)
Truillet, Charles (AUTHOR)
Pokaż więcej
Źródło:
European Journal of Nuclear Medicine & Molecular Imaging. Sep2023, Vol. 50 Issue 11, p3192-3201. 10p. 1 Color Photograph, 4 Graphs.
Czasopismo naukowe
Tytuł:
Distribution of cionin, a cholecystokinin/gastrin family peptide, and its receptor in the central nervous system of Ciona intestinalis type A.
Autorzy:
Taniguchi, Shiho
Nakayama, Satoshi
Iguchi, Rin
Sasakura, Yasunori
Satake, Honoo
Wada, Shuichi
Suzuki, Nobuo
Ogasawara, Michio
Sekiguchi, Toshio
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Temat:
CIONA intestinalis
CENTRAL nervous system
PEPTIDES
CHOLECYSTOKININ
GASTRIN
ENDOTHELIN receptors
INDUCED ovulation
TASTE receptors
Źródło:
Scientific Reports; 3/15/2024, Vol. 14 Issue 1, p1-8, 8p
Czasopismo naukowe
Tytuł:
Comparison of efficacy between clazosentan and fasudil hydrochloride-based management of vasospasm after subarachnoid hemorrhage focusing on older and WFNS grade V patients: a single-center experience in Japan.
Autorzy:
Mochizuki, Tatsuki
Ryu, Bikei
Shima, Shogo
Kamijyo, Eriko
Ito, Koki
Ando, Tamon
Kushi, Kazuki
Sato, Shinsuke
Inoue, Tatsuya
Kawashima, Akitsugu
Kawamata, Takakazu
Okada, Yoshikazu
Niimi, Yasunari
Pokaż więcej
Temat:
SUBARACHNOID hemorrhage
PATIENTS' attitudes
OLDER patients
ENDOTHELIN receptors
CEREBRAL ischemia
Źródło:
Neurosurgical Review; 3/13/2024, Vol. 47 Issue 1, p1-11, 11p
Terminy geograficzne:
JAPAN
Czasopismo naukowe
Tytuł:
Intravenous Ganaxolone: Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability in Healthy Adults.
Autorzy:
Gasior, Maciej
Husain, Aatif
Barra, Megan E.
Raja, Shruti M.
MacLeod, David
Guptill, Jeffrey T.
Vaitkevicius, Henrikas
Rybak, Eva
Pokaż więcej
Temat:
PHARMACODYNAMICS
PHARMACOKINETICS
ADULTS
BOLUS drug administration
STATUS epilepticus
WAKEFULNESS
DEGLUTITION
ENDOTHELIN receptors
PILOCARPINE
Źródło:
Clinical Pharmacology in Drug Development; Mar2024, Vol. 13 Issue 3, p248-258, 11p
Terminy geograficzne:
UNITED States
Czasopismo naukowe
Tytuł:
Tumor biomarkers in evaluating the severity and prognosis of idiopathic pulmonary arterial hypertension: A comprehensive analysis.
Autorzy:
Li, Xin
Zhang, Yi
Zhang, Sicheng
Zhao, Qing
Jin, Qi
Duan, Anqi
Huang, Zhihua
Gao, Luyang
Wang, Yijia
Li, Sicong
Zhao, Zhihui
Luo, Qin
Liu, Zhihong
Pokaż więcej
Temat:
TUMOR markers
PULMONARY arterial hypertension
PROPORTIONAL hazards models
PULMONARY hypertension
ENDOTHELIN receptors
PROGNOSIS
PROGRESSION-free survival
IMMUNITY
Źródło:
CTS: Clinical & Translational Science; Mar2024, Vol. 17 Issue 3, p1-11, 11p
Czasopismo naukowe
Tytuł:
Safety, pharmacokinetics, and pharmacodynamics in healthy Chinese volunteers treated with SC0062, a highly selective endothelin‐A receptor antagonist.
Autorzy:
Liu, Yun
Wang, Wei
Qian, Hongjie
Gui, Yuzhou
Wang, Yating
Song, Rong
Chen, Qian
Rowinsky, Eric
Wang, Sheng
Liang, Xiaoguang
Gu, Kaicun
Zhou, Bo
Zhang, Weiwei
Zhang, Liqin
Yu, Chen
Jia, Jingying
Pokaż więcej
Temat:
ENDOTHELINS
PULMONARY arterial hypertension
PHARMACODYNAMICS
PHARMACOKINETICS
CHRONIC kidney failure
BILE acids
ENDOTHELIN receptors
Źródło:
CTS: Clinical & Translational Science; Mar2024, Vol. 17 Issue 3, p1-14, 14p
Czasopismo naukowe
Tytuł:
The Role of the Endocrine System in the Regulation of Acid–Base Balance by the Kidney and the Progression of Chronic Kidney Disease.
Autorzy:
Nagami, Glenn T.
Kraut, Jeffrey A.
Pokaż więcej
Temat:
CHRONIC kidney failure
ENDOCRINE system
THYROID hormones
ANGIOTENSIN II
ENDOTHELIN receptors
KIDNEYS
ACID-base imbalances
Źródło:
International Journal of Molecular Sciences; Feb2024, Vol. 25 Issue 4, p2420, 19p
Czasopismo naukowe
Tytuł:
Renal Expression and Localization of the Receptor for (Pro)renin and Its Ligands in Rodent Models of Diabetes, Metabolic Syndrome, and Age-Dependent Focal and Segmental Glomerulosclerosis.
Autorzy:
Iacobini, Carla
Vitale, Martina
Sentinelli, Federica
Haxhi, Jonida
Pugliese, Giuseppe
Menini, Stefano
Pokaż więcej
Temat:
FOCAL segmental glomerulosclerosis
GENE expression
METABOLIC syndrome
PRORENIN receptor
RENIN
ENDOTHELIN receptors
Źródło:
International Journal of Molecular Sciences; Feb2024, Vol. 25 Issue 4, p2217, 14p
Czasopismo naukowe
Tytuł:
Impact of different sequential triple oral combination therapies based selexipag on outcomes in pulmonary arterial hypertension.
Autorzy:
Hu, Xiaoyi
Yuan, Ping
Chen, Jun
Wang, Shang
Zhao, Hui
Wei, Yaqin
Fu, Jiaqi
Chen, Fadong
Ruan, Hongyun
Zhang, Wei
Zhou, Yanli
Wang, Qiqi
Xu, Xiaoling
Feng, Kefu
Guo, Jianzhou
Gong, Sugang
Zhang, Ruifeng
Zhao, Qinhua
Wang, Lan
Pokaż więcej
Temat:
PULMONARY arterial hypertension
PHOSPHODIESTERASE inhibitors
ENDOTHELIN receptors
SYSTOLIC blood pressure
OVERALL survival
PULMONARY hypertension
Źródło:
Clinical Cardiology; Feb2024, Vol. 47 Issue 2, p1-10, 10p
Przedsiębiorstwo/ jednostka:
WORLD Health Organization
Czasopismo naukowe
Tytuł:
Ameliorative effect of montelukast against STZ induced diabetic nephropathy: targeting HMGB1, TLR4, NF-κB, NLRP3 inflammasome, and autophagy pathways.
Autorzy:
Awad, Ahmed M.
Elshaer, Sally L.
Gangaraju, Rajashekhar
Abdelaziz, Rania R.
Nader, Manar A.
Pokaż więcej
Temat:
RECEPTOR for advanced glycation end products (RAGE)
NLRP3 protein
DIABETIC nephropathies
NF-kappa B
ENDOTHELIN receptors
ADVANCED glycation end-products
AUTOPHAGY
INSULIN
Źródło:
Inflammopharmacology; Feb2024, Vol. 32 Issue 1, p495-508, 14p
Czasopismo naukowe
Tytuł:
Effect of Multiple Doses of Sparsentan on the Single‐Dose Pharmacokinetics of Dapagliflozin: An Open‐Label Drug–Drug Interaction Study in Healthy Adults.
Autorzy:
Chen, Shang‐Chiung (AUTHOR)
Cai, Danlin (AUTHOR)
Winnett, Claire (AUTHOR)
Nguyen, Mai (AUTHOR)
Verma, Neeraj (AUTHOR)
Liu, Kai (AUTHOR)
Preciado, Priscila (AUTHOR)
Pokaż więcej
Źródło:
Clinical Pharmacology in Drug Development. May2023, Vol. 12 Issue 5, p535-541. 7p.
Czasopismo naukowe
Tytuł:
Proteases and their inhibitors involved in Schistosoma mansoni egg-host interaction revealed by comparative transcriptomics with Fasciola hepatica eggs.
Autorzy:
Peterkova, Kristyna (AUTHOR)
Vorel, Jiri (AUTHOR)
Ilgova, Jana (AUTHOR)
Ostasov, Pavel (AUTHOR)
Fajtova, Pavla (AUTHOR)
Konecny, Lukas (AUTHOR)
Chanova, Marta (AUTHOR)
Kasny, Martin (AUTHOR)
Horn, Martin (AUTHOR)
Dvorak, Jan (AUTHOR)
Pokaż więcej
Źródło:
International Journal for Parasitology. May2023, Vol. 53 Issue 5/6, p253-263. 11p.
Czasopismo naukowe
Tytuł:
Evaluating the efficacy and safety of oral triple sequential combination therapy for treating patients with pulmonary arterial hypertension: A multicenter retrospective study.
Autorzy:
Zhao, Qin‐Hua (AUTHOR)
Chen, Jun (AUTHOR)
Chen, Fa‐Dong (AUTHOR)
Ruan, Hong‐Yun (AUTHOR)
Zhang, Wei (AUTHOR)
Zhou, Yan‐Li (AUTHOR)
Wang, Qi‐Qi (AUTHOR)
Xu, Xiao‐Ling (AUTHOR)
Feng, Ke‐Fu (AUTHOR)
Guo, Jian‐Zhou (AUTHOR)
Gong, Su‐Gang (AUTHOR)
Zhang, Rui‐Feng (AUTHOR)
Wang, Lan (AUTHOR)
Pokaż więcej
Źródło:
Pulmonary Circulation. Jan2024, Vol. 14 Issue 1, p1-12. 12p.
Czasopismo naukowe
Tytuł:
Secondhand cigarette smoke induces increased expression of contractile endothelin receptors in rat coronary arteries via a MEK1/2 sensitive mechanism.
Autorzy:
Cao, Lei (AUTHOR)
Lindstedt, Isak (AUTHOR)
Edvinsson, Marie-Louise (AUTHOR)
Ping, Na-Na (AUTHOR)
Cao, Yong-Xiao (AUTHOR)
Edvinsson, Lars (AUTHOR)
Pokaż więcej
Źródło:
Scandinavian Cardiovascular Journal. Feb2021, Vol. 55 Issue 1, p50-55. 6p.
Czasopismo naukowe
Tytuł:
Liver injury due to endothelin receptor antagonists: a real-world study based on post-marketing drug monitoring data.
Autorzy:
Dong, Shichao
Guo, Xiaofei
Wang, Huayu
Sun, Chuan
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Temat:
ENDOTHELIN receptors
DRUG monitoring
LIVER injuries
PULMONARY arterial hypertension
BAYESIAN analysis
Źródło:
Therapeutic Advances in Respiratory Disease; 1/5/2024, p1-15, 15p
Przedsiębiorstwo/ jednostka:
UNITED States. Food & Drug Administration
Czasopismo naukowe
Tytuł:
Evaluation of NTP42, a novel thromboxane receptor antagonist, in a first-in-human phase I clinical trial.
Autorzy:
Reid, Helen M.
Maginn, Mark
Perkins, C. Michael
Mulvaney, Eamon P.
Boyce, Malcolm
Yamamoto, Takahiro
Kinsella, B. Therese
Pokaż więcej
Temat:
BLOOD platelet aggregation
CLINICAL trials
PULMONARY arterial hypertension
ENDOTHELIN receptors
BONE morphogenetic protein receptors
THERAPEUTICS
Źródło:
Frontiers in Pharmacology; 2024, p1-13, 13p
Czasopismo naukowe
Tytuł:
Microfabricated potentiometric sensor based on a carbon nanotube transducer layer for selective Bosentan determination.
Autorzy:
Trabik, Yossra Ahmed
Ismail, Reham Abd El-Aziz
Ayad, Miriam Farid
Hussein, Lobna Abd El-Aziz
Mahmoud, Amr Mohamed
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Temat:
CARBON nanotubes
MULTIWALLED carbon nanotubes
DOSAGE forms of drugs
TRANSDUCERS
ENDOTHELIN receptors
ULTRASONIC transducers
ELECTROCHEMICAL sensors
Źródło:
Reviews in Analytical Chemistry; Jan2024, Vol. 43 Issue 1, p1-11, 11p
Czasopismo naukowe
Czasopismo naukowe
Tytuł:
Pulmonary Hypertension: Intensification and Personalization of Combination Rx (PHoenix): A phase IV randomized trial for the evaluation of dose‐response and clinical efficacy of riociguat and selexipag using implanted technologies.
Autorzy:
Varian, Frances
Dick, Jennifer
Battersby, Christian
Roman, Stefan
Ablott, Jenna
Watson, Lisa
Binmahfooz, Sarah
Zafar, Hamza
Colgan, Gerry
Cannon, John
Suntharalingam, Jay
Lordan, Jim
Howard, Luke
McCabe, Colm
Wort, John
Price, Laura
Church, Colin
Hamilton, Neil
Armstrong, Iain
Hameed, Abdul
Pokaż więcej
Temat:
PULMONARY hypertension
QUALITY of life measurement
PHOSPHODIESTERASE inhibitors
PULMONARY arterial hypertension
ENDOTHELIN receptors
MAGNETIC resonance imaging
Źródło:
Pulmonary Circulation; Jan2024, Vol. 14 Issue 1, p1-13, 13p
Terminy geograficzne:
PHOENIX (Ariz.)
Czasopismo naukowe
Tytuł:
Therapeutic properties, biological effects, antiliver cancer, and anticolon cancer effects of some natural compounds: A biochemical approach.
Autorzy:
Li, Long
Zhu, Yu
Huang, Ying‐Guang
Hou, De‐Zhi
Ahmed Zaki, Mohamed Samir
Sideeg, Abulqasim M.
Mohammed, Heitham
El‐kott, Attalla F.
Al‐Saeed, Fatimah A.
Ling, Ping
Pokaż więcej
Temat:
PLANT pigments
ENDOTHELIN receptors
MOLECULAR docking
PROTEIN receptors
DRUG design
CD47 antigen
Źródło:
Journal of Biochemical & Molecular Toxicology; Jan2024, Vol. 38 Issue 1, p1-11, 11p
Czasopismo naukowe
Tytuł:
Effect of lemborexant on pharmacokinetics of clozapine: A potential drug–drug interaction mediated by time‐dependent inhibition of CYP3A4.
Autorzy:
Watanabe, Kenya
Misaka, Shingen
Kanno‐Nozaki, Keiko
Chiyoda, Takaaki
Suzuki, Yuhei
Sato, Akiko
Suto, Takahiro
Kuroda, Junko
Shimomura, Kenju
Miura, Itaru
Yabe, Hirooki
Pokaż więcej
Temat:
DRUG interactions
CYTOCHROME P-450 CYP3A
CLOZAPINE
ORAL drug administration
PHARMACOKINETICS
OREXINS
ENDOTHELIN receptors
Źródło:
British Journal of Clinical Pharmacology; Jan2024, Vol. 90 Issue 1, p354-359, 6p
Czasopismo naukowe
Tytuł:
Copy number loss of KDM5D may be a predictive biomarker for ATR inhibitor treatment in male patients with pulmonary squamous cell carcinoma.
Autorzy:
Ura, Ayako
Hayashi, Takuo
Komura, Kazumasa
Hosoya, Masaki
Takamochi, Kazuya
Sato, Eiichi
Saito, Satomi
Wakai, Susumu
Handa, Takafumi
Saito, Tsuyoshi
Kato, Shunsuke
Suzuki, Kenji
Yao, Takashi
Pokaż więcej
Temat:
SQUAMOUS cell carcinoma
FLUORESCENCE in situ hybridization
BIOMARKERS
DNA repair
PROGRAMMED cell death 1 receptors
GENE expression
ENDOTHELIN receptors
Źródło:
Journal of Pathology: Clinical Research; Jan2024, Vol. 10 Issue 1, p1-12, 12p
Czasopismo naukowe
Tytuł:
Amyloid Beta Oligomers Activate Death Receptors and Mitochondria-Mediated Apoptotic Pathways in Cerebral Vascular Smooth Muscle Cells; Protective Effects of Carbonic Anhydrase Inhibitors.
Autorzy:
Anzovino, Amy
Canepa, Elisa
Alves, Micaelly
Lemon, Nicole L.
Carare, Roxana O.
Fossati, Silvia
Pokaż więcej
Temat:
VASCULAR smooth muscle
CARBONIC anhydrase inhibitors
MUSCLE cells
DEATH receptors
CEREBRAL circulation
AMYLOID
ENDOTHELIN receptors
Źródło:
Cells (2073-4409); Dec2023, Vol. 12 Issue 24, p2840, 22p
Przedsiębiorstwo/ jednostka:
UNITED States. Food & Drug Administration
Czasopismo naukowe
Tytuł:
Angiotensin-Converting Enzyme 2 (ACE2) Signaling in Pulmonary Arterial Hypertension: Underpinning Mechanisms and Potential Targeting Strategies.
Autorzy:
Papavassiliou, Kostas A.
Gogou, Vassiliki A.
Papavassiliou, Athanasios G.
Pokaż więcej
Temat:
PULMONARY arterial hypertension
ANGIOTENSIN converting enzyme
VASCULAR remodeling
G protein coupled receptors
ENDOTHELIN receptors
DISEASE progression
Źródło:
International Journal of Molecular Sciences; Dec2023, Vol. 24 Issue 24, p17441, 10p
Czasopismo naukowe
Tytuł:
The novel roles of YULINK in the migration, proliferation and glycolysis of pulmonary arterial smooth muscle cells: implications for pulmonary arterial hypertension.
Autorzy:
Wu, Yi-Chia
Wang, Wei-Ting
Yang, Ming-Chun
Su, Yu-Tsun
Yeh, Jwu-Lai
Hsu, Jong-Hau
Wu, Jiunn-Ren
Pokaż więcej
Temat:
PULMONARY arterial hypertension
PLATELET-derived growth factor receptors
SMOOTH muscle
MUSCLE cells
FOCAL adhesion kinase
BONE morphogenetic protein receptors
GLUCOSE transporters
ENDOTHELIN receptors
Źródło:
Biological Research; 12/7/2023, Vol. 56 Issue 1, p1-16, 16p
Czasopismo naukowe
Tytuł:
Practical Considerations for the Use of Sparsentan in the Treatment of Patients with IgAN in Clinical Practice.
Autorzy:
Campbell, Kirk N
Griffin, Siân
Trachtman, Howard
Geletka, Rob
Wong, Muh Geot
Pokaż więcej
Temat:
IGA glomerulonephritis
ANGIOTENSIN receptors
ENDOTHELIN receptors
KIDNEY failure
YOUNG adults
KIDNEY physiology
Źródło:
International Journal of Nephrology & Renovascular Disease; Dec2023, Vol. 16, p281-291, 11p
Przedsiębiorstwo/ jednostka:
UNITED States. Food & Drug Administration
Czasopismo naukowe
Tytuł:
Intratracheally Administered Peptide-Modified Lipid Admixture Containing Fasudil and/or DETA NONOate Ameliorates Various Pathologies of Pulmonary Arterial Hypertension.
Autorzy:
Sarkar, Tanoy
Moinuddin, Sakib M.
Isbatan, Ayman
Chen, Jiwang
Mann, David
Ahsan, Fakhrul
Pokaż więcej
Temat:
PULMONARY arterial hypertension
TARGETED drug delivery
COMBINATION drug therapy
SYSTOLIC blood pressure
ENDOTHELIN receptors
LIPIDS
Źródło:
Pharmaceuticals (14248247); Dec2023, Vol. 16 Issue 12, p1656, 15p
Czasopismo naukowe
Tytuł:
IL-1β-mediated adaptive reprogramming of endogenous human cardiac fibroblasts to cells with immune features during fibrotic remodeling.
Autorzy:
Siamwala, Jamila H.
Pagano, Francesco S.
Dubielecka, Patrycja M.
Ivey, Malina J.
Guirao-Abad, Jose Pedro
Zhao, Alexander
Chen, Sonja
Granston, Haley
Jeong, Jae Yun
Rounds, Sharon
Kanisicak, Onur
Sadayappan, Sakthivel
Gilbert, Richard J.
Pokaż więcej
Temat:
HEART cells
PULMONARY arterial hypertension
PULMONARY fibrosis
CELL physiology
FIBROBLASTS
ENDOTHELIN receptors
Źródło:
Communications Biology; 11/25/2023, Vol. 6 Issue 1, p1-21, 21p
Czasopismo naukowe
Tytuł:
Computational exploration of novel ROCK2 inhibitors for cardiovascular disease management; insights from high-throughput virtual screening, molecular docking, DFT and MD simulation.
Autorzy:
Ali, Iqra
Iqbal, Muhammad Nasir
Ibrahim, Muhammad
Haq, Ihtisham Ul
Alonazi, Wadi B.
Siddiqi, Abdul Rauf
Pokaż więcej
Temat:
DISEASE management
HIGH throughput screening (Drug development)
MOLECULAR docking
CARDIOVASCULAR diseases
CHEMICAL libraries
ENDOTHELIN receptors
Źródło:
PLoS ONE; 11/16/2023, Vol. 18 Issue 11, p1-25, 25p
Czasopismo naukowe
Tytuł:
The Role of Clonal Hematopoiesis of Indeterminant Potential and DNA (Cytosine-5)-Methyltransferase Dysregulation in Pulmonary Arterial Hypertension and Other Cardiovascular Diseases.
Autorzy:
Emon, Isaac M.
Al-Qazazi, Ruaa
Rauh, Michael J.
Archer, Stephen L.
Pokaż więcej
Temat:
PULMONARY arterial hypertension
CARDIOVASCULAR diseases
PULMONARY artery diseases
BLOOD diseases
SOMATIC mutation
ENDOTHELIN receptors
BONE morphogenetic protein receptors
METHYLTRANSFERASES
Źródło:
Cells (2073-4409); Nov2023, Vol. 12 Issue 21, p2528, 27p
Czasopismo naukowe
Tytuł:
Pharmacokinetics, pharmacodynamics and safety profile of the dual orexin receptor antagonist vornorexant/TS‐142 in healthy Japanese participants following single/multiple dosing: Randomized, double‐blind, placebo‐controlled phase‐1 studies
Autorzy:
Kambe, Daiji
Hasegawa, Sayaka
Imadera, Yumiko
Mano, Yoko
Matsushita, Isao
Konno, Yoshihiro
Ogo, Hiroki
Uchimura, Naohisa
Uchiyama, Makoto
Pokaż więcej
Temat:
PHARMACODYNAMICS
OLDER people
PHARMACOKINETICS
ENDOTHELIN receptors
FOOD consumption
OREXINS
MOTOR ability testing
INGESTION
PSYCHOLOGY of movement
Źródło:
Basic & Clinical Pharmacology & Toxicology; Nov2023, Vol. 133 Issue 5, p576-591, 16p
Czasopismo naukowe
Tytuł:
Hair graying with aging in mice carrying oncogenic RET.
Autorzy:
Iida, Machiko (AUTHOR)
Tazaki, Akira (AUTHOR)
Yajima, Ichiro (AUTHOR)
Ohgami, Nobutaka (AUTHOR)
Taguchi, Nobuhiko (AUTHOR)
Goto, Yuji (AUTHOR)
Kumasaka, Mayuko Y. (AUTHOR)
Prévost‐Blondel, Armelle (AUTHOR)
Kono, Michihiro (AUTHOR)
Akiyama, Masashi (AUTHOR)
Takahashi, Masahide (AUTHOR)
Kato, Masashi (AUTHOR)
Pokaż więcej
Źródło:
Aging Cell. Nov2020, Vol. 19 Issue 11, p1-14. 14p.
Czasopismo naukowe
Tytuł:
Endothelin receptor antagonist improves donor lung function in an ex vivo perfusion system.
Autorzy:
Walweel, K. (AUTHOR)
Skeggs, K. (AUTHOR)
Boon, A. C. (AUTHOR)
See Hoe, L. E. (AUTHOR)
Bouquet, M. (AUTHOR)
Obonyo, N. G. (AUTHOR)
Pedersen, S. E. (AUTHOR)
Diab, S. D. (AUTHOR)
Passmore, M. R. (AUTHOR)
Hyslop, K. (AUTHOR)
Wood, E. S. (AUTHOR)
Reid, J. (AUTHOR)
Colombo, S. M. (AUTHOR)
Bartnikowski, N. J. (AUTHOR)
Wells, M. A. (AUTHOR)
Black, D. (AUTHOR)
Pimenta, L. P. (AUTHOR)
Stevenson, A. K. (AUTHOR)
Bisht, K. (AUTHOR)
Marshall, L. (AUTHOR)
Pokaż więcej
Źródło:
Journal of Biomedical Science. 10/2/2020, Vol. 27 Issue 1, p1-9. 9p.
Czasopismo naukowe

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