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Wyszukujesz frazę ""enzymes"" wg kryterium: Temat


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Tytuł :
Enzymes in biotechnology: Critical platform technologies for bioprocess development.
Autorzy :
Katsimpouras C; Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, 02139 MA, USA.
Stephanopoulos G; Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, 02139 MA, USA. Electronic address: .
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Źródło :
Current opinion in biotechnology [Curr Opin Biotechnol] 2021 Jun; Vol. 69, pp. 91-102. Date of Electronic Publication: 2021 Jan 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Enzymes, Immobilized*
Protein Engineering*
Biotechnology ; Catalysis ; Cell-Free System ; Enzymes/genetics
Czasopismo naukowe
Tytuł :
Stabilization of ω-transaminase from Pseudomonas fluorescens by immobilization techniques.
Autorzy :
Velasco-Lozano S; Catálisis Heterogénea en Síntesis Orgánicas Selectivas, Instituto de Síntesis Química y Catálisis Homogénea (ISQCH-CSIC), University of Zaragoza, Pedro Cerbuna, 12, 50009 Zaragoza, Spain; Heterogeneous Biocatalysis Laboratory, CICbiomaGUNE Basque Research and Technology Alliance (BRTA), Paseo de Miramón, 182, 20014 Donostia-San Sebastián, Spain. Electronic address: .
Jackson E; Laboratorio de Biotecnología, Universidad ORT Uruguay, Cuareim 1441, 11100 Montevideo, Uruguay.
Ripoll M; Laboratorio de Biotecnología, Universidad ORT Uruguay, Cuareim 1441, 11100 Montevideo, Uruguay.
López-Gallego F; Catálisis Heterogénea en Síntesis Orgánicas Selectivas, Instituto de Síntesis Química y Catálisis Homogénea (ISQCH-CSIC), University of Zaragoza, Pedro Cerbuna, 12, 50009 Zaragoza, Spain; Heterogeneous Biocatalysis Laboratory, CICbiomaGUNE Basque Research and Technology Alliance (BRTA), Paseo de Miramón, 182, 20014 Donostia-San Sebastián, Spain; IKERBASQUE, Basque Foundation for Science, Maria Diaz de Haro 3, 48013 Bilbao, Spain.
Betancor L; Laboratorio de Biotecnología, Universidad ORT Uruguay, Cuareim 1441, 11100 Montevideo, Uruguay. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Dec 01; Vol. 164, pp. 4318-4328. Date of Electronic Publication: 2020 Sep 06.
Typ publikacji :
Journal Article
MeSH Terms :
Enzymes, Immobilized*
Pseudomonas fluorescens/*enzymology
Transaminases/*chemistry
Chromatography, Gas ; Cross-Linking Reagents/chemistry ; Enzyme Activation ; Enzyme Stability ; Enzymes ; Kinetics ; Protein Conformation
Czasopismo naukowe
Tytuł :
Xylanase immobilization onto trichlorotriazine-functionalized polyethylene glycol grafted magnetic nanoparticles: A thermostable and robust nanobiocatalyst for fruit juice clarification.
Autorzy :
Kharazmi S; Department of Biotechnology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan 81746-73441, Iran.
Taheri-Kafrani A; Department of Biotechnology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan 81746-73441, Iran. Electronic address: .
Soozanipour A; Department of Biotechnology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan 81746-73441, Iran.
Nasrollahzadeh M; Department of Chemistry, Faculty of Science, University of Qom, Qom 3716146611, Iran.
Varma RS; Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacky University, Šlechtitelů 27, 783 71 Olomouc, Czech Republic.
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Nov 15; Vol. 163, pp. 402-413. Date of Electronic Publication: 2020 Jul 03.
Typ publikacji :
Journal Article
MeSH Terms :
Enzymes, Immobilized*
Fruit and Vegetable Juices*
Magnetite Nanoparticles/*chemistry
Polyethylene Glycols/*chemistry
Triazines/*chemistry
Xylosidases/*chemistry
Enzyme Stability ; Enzymes ; Kinetics ; Spectrum Analysis ; Temperature ; Thermodynamics
Czasopismo naukowe
Tytuł :
Enzymatic Cascade Reactions Mediated by Highly Efficient Biomimetic Quasi Metal-Organic Frameworks.
Autorzy :
Xia H; Guangdong Provincial Key Lab of Green Chemical Product Technology, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China.
Li N; Guangdong Provincial Key Lab of Green Chemical Product Technology, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China.
Huang W; Guangdong Provincial Key Lab of Green Chemical Product Technology, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China.
Song Y; Guangdong Provincial Key Lab of Green Chemical Product Technology, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China.
Jiang Y; Guangdong Provincial Key Lab of Green Chemical Product Technology, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China.
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Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2021 May 19; Vol. 13 (19), pp. 22240-22253. Date of Electronic Publication: 2021 May 09.
Typ publikacji :
Journal Article
MeSH Terms :
Biomimetics*
Enzymes/*chemistry
Metal-Organic Frameworks/*chemistry
Catalysis ; Enzymes, Immobilized/chemistry ; Hot Temperature
Czasopismo naukowe
Tytuł :
A Concerted Action of UBA5 C-Terminal Unstructured Regions Is Important for Transfer of Activated UFM1 to UFC1.
Autorzy :
Wesch N; Institute of Biophysical Chemistry, Center for Biomolecular Magnetic Resonance, Goethe-University Frankfurt, 60438 Frankfurt am Main, Germany.
Löhr F; Institute of Biophysical Chemistry, Center for Biomolecular Magnetic Resonance, Goethe-University Frankfurt, 60438 Frankfurt am Main, Germany.
Rogova N; Institute of Biophysical Chemistry, Center for Biomolecular Magnetic Resonance, Goethe-University Frankfurt, 60438 Frankfurt am Main, Germany.
Dötsch V; Institute of Biophysical Chemistry, Center for Biomolecular Magnetic Resonance, Goethe-University Frankfurt, 60438 Frankfurt am Main, Germany.; Structural Genomics Consortium, Buchmann Institute for Life Sciences, Goethe-University Frankfurt, 60438 Frankfurt am Main, Germany.
Rogov VV; Institute of Biophysical Chemistry, Center for Biomolecular Magnetic Resonance, Goethe-University Frankfurt, 60438 Frankfurt am Main, Germany.; Structural Genomics Consortium, Buchmann Institute for Life Sciences, Goethe-University Frankfurt, 60438 Frankfurt am Main, Germany.; Institute of Pharmaceutical Chemistry, Goethe-University Frankfurt, 60438 Frankfurt am Main, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 09; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 09.
Typ publikacji :
Journal Article
MeSH Terms :
Proteins/*chemistry
Ubiquitin-Activating Enzymes/*chemistry
Ubiquitin-Conjugating Enzymes/*chemistry
Calorimetry, Differential Scanning ; Gene Expression ; Magnetic Resonance Spectroscopy ; Mutation ; Peptides/chemistry ; Protein Binding ; Protein Domains ; Proteins/genetics ; Proteins/metabolism ; Recombinant Proteins ; Thermodynamics ; Ubiquitin-Activating Enzymes/genetics ; Ubiquitin-Activating Enzymes/metabolism ; Ubiquitin-Conjugating Enzymes/genetics ; Ubiquitin-Conjugating Enzymes/metabolism
Czasopismo naukowe
Tytuł :
The power of electrified nanoconfinement for energising, controlling and observing long enzyme cascades.
Autorzy :
Morello G; Inorganic Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford, OX13QR, UK.
Megarity CF; Inorganic Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford, OX13QR, UK.
Armstrong FA; Inorganic Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford, OX13QR, UK. .
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Źródło :
Nature communications [Nat Commun] 2021 Jan 12; Vol. 12 (1), pp. 340. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Electrochemistry*
Enzymes/*metabolism
Biocatalysis ; Electrodes ; Enzymes, Immobilized/metabolism ; Ferredoxin-NADP Reductase/metabolism ; Hydrodynamics ; Kinetics ; Nanoparticles/chemistry ; Nanopores
Czasopismo naukowe
Tytuł :
[Advances of enzymes in the applications of disease treatment and drug preparation].
Autorzy :
Zhou R; Department of Bioengineering and Biotechnology, College of Chemical Engineering, Huaqiao University, Xiamen 361021, Fujian, China.
Liu X; Department of Bioengineering and Biotechnology, College of Chemical Engineering, Huaqiao University, Xiamen 361021, Fujian, China.
Zeng B; Department of Bioengineering and Biotechnology, College of Chemical Engineering, Huaqiao University, Xiamen 361021, Fujian, China.
Jiang W; Department of Bioengineering and Biotechnology, College of Chemical Engineering, Huaqiao University, Xiamen 361021, Fujian, China.
Zhang G; Department of Bioengineering and Biotechnology, College of Chemical Engineering, Huaqiao University, Xiamen 361021, Fujian, China.
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Źródło :
Sheng wu gong cheng xue bao = Chinese journal of biotechnology [Sheng Wu Gong Cheng Xue Bao] 2021 Jul 25; Vol. 37 (7), pp. 2256-2271.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biotechnology*
Enzymes*/metabolism
Biocatalysis ; Catalysis ; Drug Compounding
Czasopismo naukowe
Tytuł :
Magnetic particles for enzyme immobilization: A versatile support for ligand screening.
Autorzy :
Trindade Ximenes IA; Laboratório SINCROMA, Instituto de Química, Departamento de Química Orgânica, Universidade Federal Fluminense, Niterói, RJ, Brazil.
de Oliveira PCO; Laboratório SINCROMA, Instituto de Química, Departamento de Química Orgânica, Universidade Federal Fluminense, Niterói, RJ, Brazil.
Wegermann CA; Laboratório SINCROMA, Instituto de Química, Departamento de Química Orgânica, Universidade Federal Fluminense, Niterói, RJ, Brazil.
de Moraes MC; Laboratório SINCROMA, Instituto de Química, Departamento de Química Orgânica, Universidade Federal Fluminense, Niterói, RJ, Brazil. Electronic address: .
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Źródło :
Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2021 Sep 10; Vol. 204, pp. 114286. Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Enzymes, Immobilized*
Magnetics*
Drug Discovery ; Ligands ; Magnetic Phenomena
Czasopismo naukowe
Tytuł :
Antibody toolkit reveals N-terminally ubiquitinated substrates of UBE2W.
Autorzy :
Davies CW; Department of Antibody Engineering, Genentech, Inc., South San Francisco, CA, USA.
Vidal SE; Departments of Molecular Oncology and Early Discovery Biochemistry, Genentech, Inc., South San Francisco, CA, USA.
Phu L; Department of Microchemistry, Proteomics, and Lipidomics, Genentech, Inc., South San Francisco, CA, USA.
Sudhamsu J; Department of Structural Biology, Genentech, Inc., South San Francisco, CA, USA.
Hinkle TB; Department of Microchemistry, Proteomics, and Lipidomics, Genentech, Inc., South San Francisco, CA, USA.
Chan Rosenberg S; Departments of Molecular Oncology and Early Discovery Biochemistry, Genentech, Inc., South San Francisco, CA, USA.
Schumacher FR; Department of Microchemistry, Proteomics, and Lipidomics, Genentech, Inc., South San Francisco, CA, USA.
Zeng YJ; Department of Microchemistry, Proteomics, and Lipidomics, Genentech, Inc., South San Francisco, CA, USA.
Schwerdtfeger C; Boston Biochem, a Bio-Techne Brand 840 Memorial Drive, Cambridge, MA, USA.
Peterson AS; Department of Molecular Biology, Genentech, Inc., South San Francisco, CA, USA.
Lill JR; Department of Microchemistry, Proteomics, and Lipidomics, Genentech, Inc., South San Francisco, CA, USA.
Rose CM; Department of Microchemistry, Proteomics, and Lipidomics, Genentech, Inc., South San Francisco, CA, USA.
Shaw AS; Research Biology, Genentech, Inc., South San Francisco, CA, USA.
Wertz IE; Departments of Molecular Oncology and Early Discovery Biochemistry, Genentech, Inc., South San Francisco, CA, USA. .; Bristol Myers Squibb, 1000 Sierra Point Parkway, Brisbane, CA, USA. .
Kirkpatrick DS; Department of Microchemistry, Proteomics, and Lipidomics, Genentech, Inc., South San Francisco, CA, USA. .; Interline Therapeutics, South San Francisco, CA, USA. .
Koerber JT; Department of Antibody Engineering, Genentech, Inc., South San Francisco, CA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Jul 29; Vol. 12 (1), pp. 4608. Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies/*chemistry
Peptides/*chemistry
Ubiquitin-Conjugating Enzymes/*metabolism
Ubiquitinated Proteins/*metabolism
Amino Acid Sequence ; Animals ; Antibodies/immunology ; Cells, Cultured ; Crystallography, X-Ray/methods ; Humans ; Mass Spectrometry/methods ; Protein Binding ; Proteomics/methods ; Rabbits ; Ubiquitin-Conjugating Enzymes/chemistry ; Ubiquitin-Conjugating Enzymes/immunology ; Ubiquitination
Czasopismo naukowe
Tytuł :
Systematic Modification and Evaluation of Enzyme-Loaded Chitosan Nanoparticles.
Autorzy :
Lino PR; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal.
Leandro J; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal.
Figueiredo L; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal.
Amaro MP; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal.
Gonçalves LMD; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal.
Leandro P; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal.
Almeida AJ; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 26; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :
Journal Article
MeSH Terms :
Chitosan*/chemistry
Chitosan*/pharmacology
Enzymes, Immobilized*/chemistry
Enzymes, Immobilized*/pharmacology
Materials Testing*
Phenylalanine Hydroxylase*/chemistry
Phenylalanine Hydroxylase*/pharmacology
Nanoparticles/*chemistry
Drug Evaluation, Preclinical ; Enzyme Stability ; HEK293 Cells ; Hep G2 Cells ; Humans
Czasopismo naukowe
Tytuł :
A role for the Cockayne Syndrome B (CSB)-Elongin ubiquitin ligase complex in signal-dependent RNA polymerase II transcription.
Autorzy :
Weems JC; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Slaughter BD; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Unruh JR; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Weaver KJ; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Miller BD; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Delventhal KM; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Conaway JW; Stowers Institute for Medical Research, Kansas City, Missouri, USA; Department of Biochemistry & Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA. Electronic address: .
Conaway RC; Stowers Institute for Medical Research, Kansas City, Missouri, USA; Department of Biochemistry & Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2021 Jul; Vol. 297 (1), pp. 100862. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Helicases/*genetics
DNA Repair Enzymes/*genetics
Elongin/*genetics
Poly-ADP-Ribose Binding Proteins/*genetics
RNA Polymerase II/*genetics
Ubiquitin-Protein Ligases/*genetics
Animals ; Cockayne Syndrome/enzymology ; Cockayne Syndrome/genetics ; DNA Helicases/chemistry ; DNA Helicases/ultrastructure ; DNA Repair/genetics ; DNA Repair Enzymes/chemistry ; DNA Repair Enzymes/ultrastructure ; Elongin/chemistry ; Elongin/ultrastructure ; Humans ; Mice ; Multiprotein Complexes/chemistry ; Multiprotein Complexes/genetics ; Multiprotein Complexes/ultrastructure ; Poly-ADP-Ribose Binding Proteins/chemistry ; Poly-ADP-Ribose Binding Proteins/ultrastructure ; RNA Polymerase II/chemistry ; Receptors, Glucocorticoid/chemistry ; Receptors, Glucocorticoid/genetics ; Ubiquitin/chemistry ; Ubiquitin/genetics ; Ubiquitin-Protein Ligases/chemistry ; Ubiquitin-Protein Ligases/ultrastructure ; Ubiquitination/genetics
Czasopismo naukowe
Tytuł :
Evidence of synergism among three genetic variants in a patient with LMNA-related lipodystrophy and amyotrophic lateral sclerosis leading to a remarkable nuclear phenotype.
Autorzy :
Volkening K; Molecular Medicine, Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Farhan SMK; Analytic and Translational Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
Kao J; Molecular Medicine, Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Leystra-Lantz C; Molecular Medicine, Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Ang LC; Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Department of Pathology and Laboratory Medicine, London Health Sciences Centre-University Hospital, London, ON, Canada.
McIntyre A; Blackburn Cardiovascular Genetics Lab, Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Wang J; Blackburn Cardiovascular Genetics Lab, Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Hegele RA; Department of Pathology and Laboratory Medicine, London Health Sciences Centre-University Hospital, London, ON, Canada.; Blackburn Cardiovascular Genetics Lab, Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Department of Biochemistry, Western University, London, ON, Canada.
Strong MJ; Molecular Medicine, Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada. .; Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada. .
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2021 Jul; Vol. 476 (7), pp. 2633-2650. Date of Electronic Publication: 2021 Mar 04.
Typ publikacji :
Journal Article
MeSH Terms :
Amyotrophic Lateral Sclerosis*/genetics
Amyotrophic Lateral Sclerosis*/metabolism
Amyotrophic Lateral Sclerosis*/pathology
DNA Helicases*/genetics
DNA Helicases*/metabolism
Lamin Type A*/genetics
Lamin Type A*/metabolism
Lipodystrophy*/genetics
Lipodystrophy*/metabolism
Lipodystrophy*/pathology
Multifunctional Enzymes*/genetics
Multifunctional Enzymes*/metabolism
Mutation, Missense*
RNA Helicases*/genetics
RNA Helicases*/metabolism
RNA-Binding Protein FUS*/genetics
RNA-Binding Protein FUS*/metabolism
Amino Acid Substitution ; Family ; Female ; HEK293 Cells ; Humans ; Male
Czasopismo naukowe
Tytuł :
Should temozolomide be used on the basis of O -methylguanine DNA methyltransferase status in patients with advanced neuroendocrine tumors? A systematic review and meta-analysis.
Autorzy :
Trillo Aliaga P; Division of New Drugs and Early Drug Development, European Institute of Oncology IRCCS, Milan, Italy; Department of Oncology and Hematology, University of Milan, Milan, Italy.
Spada F; Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology IRCCS, Milan, Italy.
Peveri G; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Bagnardi V; Department of Statistics and Quantitative Methods, University of Milan-Bicocca, Milan, Italy.
Fumagalli C; Division of Pathology, European Institute of Oncology IRCCS, Milan, Italy.
Laffi A; Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology IRCCS, Milan, Italy.
Rubino M; Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology IRCCS, Milan, Italy.
Gervaso L; Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology IRCCS, Milan, Italy; Molecular Medicine Department, University of Pavia, Pavia, Italy.
Guerini Rocco E; Division of Pathology, European Institute of Oncology IRCCS, Milan, Italy.
Pisa E; Division of Pathology, European Institute of Oncology IRCCS, Milan, Italy.
Curigliano G; Division of New Drugs and Early Drug Development, European Institute of Oncology IRCCS, Milan, Italy; Department of Oncology and Hematology, University of Milan, Milan, Italy.
Fazio N; IEO, European Institute of Oncology, IRCCS, Milan, Italy. Electronic address: .
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Źródło :
Cancer treatment reviews [Cancer Treat Rev] 2021 Sep; Vol. 99, pp. 102261. Date of Electronic Publication: 2021 Jul 22.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
DNA Modification Methylases/*deficiency
DNA Repair Enzymes/*deficiency
Neuroendocrine Tumors/*drug therapy
Neuroendocrine Tumors/*enzymology
Tumor Suppressor Proteins/*deficiency
Clinical Trials, Phase II as Topic ; DNA Modification Methylases/metabolism ; DNA Repair Enzymes/metabolism ; Humans ; Progression-Free Survival ; Randomized Controlled Trials as Topic ; Temozolomide/administration & dosage ; Tumor Suppressor Proteins/metabolism
Czasopismo naukowe
Tytuł :
FANCD2-Associated Nuclease 1 Partially Compensates for the Lack of Exonuclease 1 in Mismatch Repair.
Autorzy :
Kratz K; Institute of Molecular Cancer Research, University of Zurichgrid.7400.3, Zurich, Switzerland.
Artola-Borán M; Institute of Molecular Cancer Research, University of Zurichgrid.7400.3, Zurich, Switzerland.
Kobayashi-Era S; Institute of Molecular Cancer Research, University of Zurichgrid.7400.3, Zurich, Switzerland.; Institute of Biochemistry of the ETH Zurichgrid.5801.c, Zurich, Switzerland.
Koh G; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.; Academic Department of Medical Genetics, The Clinical School, University of Cambridgegrid.5335.0, Cambridge, United Kingdom.; MRC Cancer Unit, The Clinical School, University of Cambridgegrid.5335.0, Cambridge, United Kingdom.
Oliveira G; Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Centre, Medical University of Viennagrid.22937.3d, Vienna, Austria.
Kobayashi S; Institute of Molecular Cancer Research, University of Zurichgrid.7400.3, Zurich, Switzerland.; Institute of Biochemistry of the ETH Zurichgrid.5801.c, Zurich, Switzerland.
Oliveira A; Institute of Molecular Cancer Research, University of Zurichgrid.7400.3, Zurich, Switzerland.; Institute of Biochemistry of the ETH Zurichgrid.5801.c, Zurich, Switzerland.
Zou X; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.; Academic Department of Medical Genetics, The Clinical School, University of Cambridgegrid.5335.0, Cambridge, United Kingdom.; MRC Cancer Unit, The Clinical School, University of Cambridgegrid.5335.0, Cambridge, United Kingdom.
Richter J; Institute of Biochemistry of the ETH Zurichgrid.5801.c, Zurich, Switzerland.
Tsuda M; Department of Radiation Genetics, Graduate School of Medicine, Kyoto Universitygrid.258799.8, Kyoto, Japan.
Sasanuma H; Department of Radiation Genetics, Graduate School of Medicine, Kyoto Universitygrid.258799.8, Kyoto, Japan.
Takeda S; Department of Radiation Genetics, Graduate School of Medicine, Kyoto Universitygrid.258799.8, Kyoto, Japan.
Loizou JI; Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Centre, Medical University of Viennagrid.22937.3d, Vienna, Austria.
Sartori AA; Institute of Molecular Cancer Research, University of Zurichgrid.7400.3, Zurich, Switzerland.
Nik-Zainal S; Academic Department of Medical Genetics, The Clinical School, University of Cambridgegrid.5335.0, Cambridge, United Kingdom.; MRC Cancer Unit, The Clinical School, University of Cambridgegrid.5335.0, Cambridge, United Kingdom.
Jiricny J; Institute of Molecular Cancer Research, University of Zurichgrid.7400.3, Zurich, Switzerland.; Institute of Biochemistry of the ETH Zurichgrid.5801.c, Zurich, Switzerland.
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Źródło :
Molecular and cellular biology [Mol Cell Biol] 2021 Aug 24; Vol. 41 (9), pp. e0030321. Date of Electronic Publication: 2021 Aug 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Mismatch Repair*
Avian Proteins/*metabolism
Endodeoxyribonucleases/*metabolism
Exodeoxyribonucleases/*metabolism
Multifunctional Enzymes/*metabolism
Amino Acid Sequence ; Animals ; Base Sequence ; Cell Line ; Chickens ; Endodeoxyribonucleases/chemistry ; Exodeoxyribonucleases/chemistry ; Exodeoxyribonucleases/deficiency ; Exodeoxyribonucleases/genetics ; Guanosine/analogs & derivatives ; HEK293 Cells ; Humans ; Methylnitronitrosoguanidine ; Multifunctional Enzymes/chemistry ; Mutation/genetics ; Thionucleosides
Czasopismo naukowe
Tytuł :
Cryo-EM of NHEJ supercomplexes provides insights into DNA repair.
Autorzy :
Chaplin AK; Department of Biochemistry, University of Cambridge, Sanger Building, Tennis Court Road, Cambridge CB2 1GA, UK. Electronic address: .
Hardwick SW; CryoEM Facility, Department of Biochemistry, University of Cambridge, Sanger Building, Tennis Court Road, Cambridge CB2 1GA, UK.
Stavridi AK; Department of Biochemistry, University of Cambridge, Sanger Building, Tennis Court Road, Cambridge CB2 1GA, UK.
Buehl CJ; College of Veterinary Medicine, Department of Microbiology & Molecular Genetics, Department of Pathobiology & Diagnostic Investigation, Michigan State University, East Lansing, MI 48824, USA.
Goff NJ; College of Veterinary Medicine, Department of Microbiology & Molecular Genetics, Department of Pathobiology & Diagnostic Investigation, Michigan State University, East Lansing, MI 48824, USA.
Ropars V; Institute for Integrative Biology of the Cell (I2BC), Institute Joliot, CEA, CNRS, Université Paris-Saclay, 91198, Gif-sur-Yvette Cedex, France.
Liang S; Department of Biochemistry, University of Cambridge, Sanger Building, Tennis Court Road, Cambridge CB2 1GA, UK.
De Oliveira TM; AstraZeneca R&D, Discovery Sciences, Mechanistic and Structural Biology, Cambridge, UK.
Chirgadze DY; CryoEM Facility, Department of Biochemistry, University of Cambridge, Sanger Building, Tennis Court Road, Cambridge CB2 1GA, UK.
Meek K; College of Veterinary Medicine, Department of Microbiology & Molecular Genetics, Department of Pathobiology & Diagnostic Investigation, Michigan State University, East Lansing, MI 48824, USA.
Charbonnier JB; Institute for Integrative Biology of the Cell (I2BC), Institute Joliot, CEA, CNRS, Université Paris-Saclay, 91198, Gif-sur-Yvette Cedex, France.
Blundell TL; Department of Biochemistry, University of Cambridge, Sanger Building, Tennis Court Road, Cambridge CB2 1GA, UK. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Aug 19; Vol. 81 (16), pp. 3400-3409.e3. Date of Electronic Publication: 2021 Aug 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Ligase ATP/*ultrastructure
DNA Repair Enzymes/*ultrastructure
DNA-Activated Protein Kinase/*ultrastructure
DNA-Binding Proteins/*ultrastructure
Multiprotein Complexes/*ultrastructure
Apoptosis/genetics ; Cryoelectron Microscopy ; DNA Breaks, Double-Stranded ; DNA Damage/genetics ; DNA End-Joining Repair/genetics ; DNA Ligase ATP/genetics ; DNA Repair/genetics ; DNA Repair Enzymes/genetics ; DNA-Activated Protein Kinase/genetics ; DNA-Binding Proteins/genetics ; Humans ; Ku Autoantigen/genetics ; Ku Autoantigen/ultrastructure ; Multiprotein Complexes/genetics ; Phosphorylation/genetics
Czasopismo naukowe
Tytuł :
Lipase immobilization on magnetic cellulose microspheres for rapid screening inhibitors from traditional herbal medicines.
Autorzy :
Liu J; CAS Key Laboratory of Chemistry of Northwestern Plant Resources, Key Laboratory for Natural Medicines of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, 730000, PR China; University of Chinese Academy of Sciences, Beijing, 100049, PR China.
Zhang HX; College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, PR China.
Shi YP; CAS Key Laboratory of Chemistry of Northwestern Plant Resources, Key Laboratory for Natural Medicines of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, 730000, PR China. Electronic address: .
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Źródło :
Talanta [Talanta] 2021 Aug 15; Vol. 231, pp. 122374. Date of Electronic Publication: 2021 Mar 30.
Typ publikacji :
Journal Article
MeSH Terms :
Enzymes, Immobilized*
Lipase*
Cellulose ; Hydrogen-Ion Concentration ; Magnetic Phenomena ; Microspheres ; Temperature
Czasopismo naukowe
Tytuł :
Dancing with oils - the interaction of lipases with different oil/water interfaces.
Autorzy :
Filipe HAL; Coimbra Chemistry Centre, Dept. of Chemistry, University of Coimbra, Rua Larga, 3004-535, Coimbra, Portugal. .
Almeida MCF; Coimbra Chemistry Centre, Dept. of Chemistry, University of Coimbra, Rua Larga, 3004-535, Coimbra, Portugal. .
Teixeira RR; Coimbra Chemistry Centre, Dept. of Chemistry, University of Coimbra, Rua Larga, 3004-535, Coimbra, Portugal. .
Esteves MIM; Coimbra Chemistry Centre, Dept. of Chemistry, University of Coimbra, Rua Larga, 3004-535, Coimbra, Portugal. .
Henriques CA; EcoXperience, HIESE, Quinta Vale do Espinhal, 3230-343, Penela, Portugal.
Antunes FE; Coimbra Chemistry Centre, Dept. of Chemistry, University of Coimbra, Rua Larga, 3004-535, Coimbra, Portugal. .
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Źródło :
Soft matter [Soft Matter] 2021 Aug 05; Vol. 17 (30), pp. 7086-7098.
Typ publikacji :
Journal Article
MeSH Terms :
Enzymes, Immobilized*
Oils*
Basidiomycota ; Eurotiales ; Rhizomucor ; Water
SCR Organism :
Moesziomyces antarcticus; Rhizomucor miehei; Thermomyces lanuginosus
Czasopismo naukowe
Tytuł :
Genome sequencing in families with congenital limb malformations.
Autorzy :
Elsner J; Institute of Medical Genetics and Human Genetics, Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Mensah MA; Institute of Medical Genetics and Human Genetics, Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.
Holtgrewe M; Core Unit Bioinformatics, Berlin Institute of Health (BIH), Berlin, Germany.
Hertzberg J; Max Planck Institute for Molecular Genetics, RG Development and Disease, Berlin, Germany.
Bigoni S; Medical Genetics Unit, Department of Mother and Child, Ferrara Sant'Anna University Hospital, Ferrara, Italy.
Busche A; Institut Für Humangenetik, Universitätsklinikum Münster, Münster, Germany.
Coutelier M; Institute of Medical Genetics and Human Genetics, Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Department of Human Genetics, Faculty of Medicine, Jewish General Hospital, McGill University, Montreal, QC, Canada.
de Silva DC; Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Elçioglu N; Department of Pediatric Genetics, Marmara University Medical School, Istanbul, Turkey.; Eastern Mediterranean University Medical School, Cyprus, Mersin 10, Turkey.
Filges I; Institut für Medizinische Genetik und Pathologie, Universitätsspital Basel, Basel, Switzerland.
Gerkes E; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Girisha KM; Department of Medical Genetics, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India.
Graul-Neumann L; Institute of Medical Genetics and Human Genetics, Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Jamsheer A; Department of Medical Genetics, Poznan University of Medical Sciences, Poznan, Poland.
Krawitz P; Institute for Genomic Statistics and Bioinformatics, University of Bonn, Bonn, Germany.
Kurth I; Institute of Human Genetics, Medical Faculty, RWTH Aachen University Hospital, Aachen, Germany.
Markus S; Fachärztin Für Humangenetik, Bischof-von-Henle-Straße 2a, Regensburg, Germany.
Megarbane A; Department of Human Genetics, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
Reis A; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Reuter MS; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Svoboda D; Kinderhandchirurgie, Medizinische Fakultät Mannheim der Universität Heidelberg, Heidelberg, Germany.
Teller C; Synlab MVZ Bad Nauheim, Mondorfstr. 1761231, Bad Nauheim, Germany.
Tuysuz B; Department of Pediatric Genetics, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Türkmen S; Institute of Medical Genetics and Human Genetics, Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; National Center of Genetics (NCG), Laboratoire National de Santé 1, Rue Louis Rech, 3555, Dudelange, Luxembourg.
Wilson M; Genetic Medicine, Children's Hospital at Westmead, Paediatrics and Child Health, Sydney, Australia.
Woitschach R; Institute of Human Genetics, University Medical Center Hamburg, Eppendorf, Germany.
Vater I; Institute of Human Genetics, University of Kiel, Kiel, Germany.
Caliebe A; Institute of Human Genetics, University of Kiel, Kiel, Germany.
Hülsemann W; Katholisches Kinderkrankenhaus Wilhelmstift, Hamburg, Germany.
Horn D; Institute of Medical Genetics and Human Genetics, Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Mundlos S; Institute of Medical Genetics and Human Genetics, Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. .; Max Planck Institute for Molecular Genetics, RG Development and Disease, Berlin, Germany. .
Spielmann M; Max Planck Institute for Molecular Genetics, RG Development and Disease, Berlin, Germany. .; Institute of Human Genetics, University of Kiel, Kiel, Germany. .; Institute of Human Genetics, University of Lübeck, Lübeck, Germany. .
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Źródło :
Human genetics [Hum Genet] 2021 Aug; Vol. 140 (8), pp. 1229-1239. Date of Electronic Publication: 2021 Jun 22.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Heterogeneity*
Mutation*
Homeodomain Proteins/*genetics
Limb Deformities, Congenital/*genetics
Transcription Factors/*genetics
Ubiquitin-Activating Enzymes/*genetics
Base Sequence ; Cohort Studies ; DNA Copy Number Variations ; Gene Expression ; Genetic Testing ; Humans ; Infant ; Limb Deformities, Congenital/metabolism ; Limb Deformities, Congenital/pathology ; Male ; Pedigree ; Transcription Factors/deficiency ; Ubiquitin-Activating Enzymes/deficiency ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
Molecular profiling of microbial community structure and their CAZymes via metagenomics, from Tsomgo lake in the Eastern Himalayas.
Autorzy :
Rai A; Department of Microbiology, University of North Bengal, Darjeeling, 734013, West Bengal, India.
Bhattacharjee A; Department of Microbiology, University of North Bengal, Darjeeling, 734013, West Bengal, India. .
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Źródło :
Archives of microbiology [Arch Microbiol] 2021 Aug; Vol. 203 (6), pp. 3135-3146. Date of Electronic Publication: 2021 Apr 04.
Typ publikacji :
Journal Article
MeSH Terms :
Bacteria*/classification
Bacteria*/enzymology
Bacteria*/genetics
Enzymes*/genetics
Lakes*/microbiology
Metagenomics*
Microbiota*/genetics
Soil Microbiology*
India ; Phylogeny
Czasopismo naukowe
Tytuł :
Analytical methods for the investigation of enzyme-catalyzed degradation of polyethylene terephthalate.
Autorzy :
Pirillo V; The Protein Factory 2.0', Dipartimento di Biotecnologie e Scienze della Vita, Università degli Studi dell'Insubria, Varese, Italy.
Pollegioni L; The Protein Factory 2.0', Dipartimento di Biotecnologie e Scienze della Vita, Università degli Studi dell'Insubria, Varese, Italy.
Molla G; The Protein Factory 2.0', Dipartimento di Biotecnologie e Scienze della Vita, Università degli Studi dell'Insubria, Varese, Italy.
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Źródło :
The FEBS journal [FEBS J] 2021 Aug; Vol. 288 (16), pp. 4730-4745. Date of Electronic Publication: 2021 May 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Enzymes/*metabolism
Polyethylene Terephthalates/*metabolism
Biocatalysis ; Enzymes/analysis ; Kinetics
Czasopismo naukowe

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