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Tytuł :
Paternal Age is Negatively Associated with Religious Behavior in a Post-60s But Not a Pre-60s US Birth Cohort: Testing a Prediction from the Social Epistasis Amplification Model.
Autorzy :
Woodley Of Menie MA; Center Leo Apostel for Interdisciplinary Studies, Vrije Universiteit Brussel, Brussels, Belgium. .; Unz Foundation, Palo Alto, CA, USA. .
Kanazawa S; School of Management, London School of Economics and Political Science, London, UK.
Pallesen J; Independent Researcher, Aarhus, Denmark.
Sarraf MA; University of Rochester, New York, NY, USA.
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Źródło :
Journal of religion and health [J Relig Health] 2020 Dec; Vol. 59 (6), pp. 2733-2752.
Typ publikacji :
Journal Article
MeSH Terms :
Epistasis, Genetic*
Paternal Age*
Religion*
Religion and Psychology*
Aged ; Aged, 80 and over ; Cohort Studies ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Social Behavior
Czasopismo naukowe
Tytuł :
FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses.
Autorzy :
Ahluwalia TS; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Gentofte, Denmark.; Department of Biology, The Bioinformatics Center, University of Copenhagen, Copenhagen, Denmark.
Eliasen AU; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.; Section for Bioinformatics, Department of Health Technology, Technical University of Denmark, Copenhagen, Denmark.
Sevelsted A; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Pedersen CT; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Stokholm J; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Chawes B; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Linneberg A; Center for Clinical Research and Disease Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Sharma A; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Weiss ST; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Evans MD; Clinical and Translational Science Institute, University of Minnesota, Minneapolis, MN, USA.
Jackson DJ; Department of Pediatrics, University of Wisconsin, Madison, WI, USA.
Morin A; Department of Human Genetics, University of Chicago, Chicago, IL, USA.
Krogfelt KA; Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark.; Department of Science and Environment, Roskilde University, Roskilde, Denmark.
Schjørring S; Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark.
Mortensen PB; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Copenhagen, Denmark.; NCRR, The National Center for Register-based research, Business and Social Sciences, Aarhus University, Aarhus C, Denmark.; CIRRAU-Center for Integrated Register-Based Research at Aarhus University, Aarhus C, Denmark.
Hougaard DM; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Copenhagen, Denmark.; Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.; Den Neonatale Screenings Biobank, SSI, Copenhagen, Denmark.
Bybjerg-Grauholm J; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Copenhagen, Denmark.; Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.; Den Neonatale Screenings Biobank, SSI, Copenhagen, Denmark.
Bækvad-Hansen M; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Copenhagen, Denmark.; Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.; Den Neonatale Screenings Biobank, SSI, Copenhagen, Denmark.
Mors O; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Copenhagen, Denmark.; Psychosis Research Unit, Aarhus University Hospital-Psychiatry, Risskov, Denmark.
Nordentoft M; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Copenhagen, Denmark.; Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen University Hospital, Copenhagen, Denmark.
Børglum AD; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Copenhagen, Denmark.; Department of Biomedicine and iSEQ, Center for Integrative Sequencing, Aarhus University, Aarhus C, Denmark.; Center for Genomics and Personalized Medicine, Central Region Denmark, Aarhus C, Denmark.
Werge T; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Copenhagen, Denmark.; Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen University Hospital, Copenhagen, Denmark.; Institute of Biological Psychiatry, Copenhagen Mental Health Services, Copenhagen, Denmark.; Center for GeoGenetics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.
Agerbo E; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Copenhagen, Denmark.; NCRR, The National Center for Register-based research, Business and Social Sciences, Aarhus University, Aarhus C, Denmark.; CIRRAU-Center for Integrated Register-Based Research at Aarhus University, Aarhus C, Denmark.
Gern JE; Department of Pediatrics, University of Wisconsin, Madison, WI, USA.
Lemanske RF Jr; Department of Pediatrics, University of Wisconsin, Madison, WI, USA.
Ober C; Department of Human Genetics, University of Chicago, Chicago, IL, USA.
Pedersen AG; Section for Bioinformatics, Department of Health Technology, Technical University of Denmark, Copenhagen, Denmark.
Bisgaard H; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Bønnelykke K; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark. .
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Źródło :
Nature communications [Nat Commun] 2020 Dec 16; Vol. 11 (1), pp. 6398. Date of Electronic Publication: 2020 Dec 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epistasis, Genetic*
ABO Blood-Group System/*genetics
Asthma/*genetics
Fucosyltransferases/*genetics
Pneumococcal Infections/*genetics
Case-Control Studies ; Child ; Child, Preschool ; Female ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Humans ; Male ; Polymorphism, Single Nucleotide ; Streptococcus pneumoniae/pathogenicity
Czasopismo naukowe
Tytuł :
Using genetics to reveal protein structure.
Autorzy :
Wang D; Division of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego (UCSD), La Jolla, CA, USA. .; Department of Cellular and Molecular Medicine, School of Medicine, UCSD, La Jolla, CA, USA.; Department of Chemistry and Biochemistry, UCSD, La Jolla, CA, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2020 Dec 11; Vol. 370 (6522), pp. 1269-1270.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Epistasis, Genetic*
Czasopismo naukowe
Tytuł :
Ecology shapes epistasis in a genotype-phenotype-fitness map for stick insect colour.
Autorzy :
Nosil P; Centre d'Ecologie Fonctionelle et Evolutive, Centre National de la Recherche Scientifique, Montpellier, France. .; Department of Biology, Utah State University, Logan, UT, USA. .
Villoutreix R; Centre d'Ecologie Fonctionelle et Evolutive, Centre National de la Recherche Scientifique, Montpellier, France.
de Carvalho CF; Centre d'Ecologie Fonctionelle et Evolutive, Centre National de la Recherche Scientifique, Montpellier, France.
Feder JL; Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Parchman TL; Department of Biology, University of Nevada Reno, Reno, NV, USA.
Gompert Z; Department of Biology, Utah State University, Logan, UT, USA.
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Źródło :
Nature ecology & evolution [Nat Ecol Evol] 2020 Dec; Vol. 4 (12), pp. 1673-1684. Date of Electronic Publication: 2020 Sep 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Epistasis, Genetic*
Insecta*/genetics
Animals ; Color ; Genotype ; Mutation ; Phenotype
Czasopismo naukowe
Tytuł :
Idiosyncratic epistasis creates universals in mutational effects and evolutionary trajectories.
Autorzy :
Lyons DM; Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI, USA.
Zou Z; Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI, USA.
Xu H; Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI, USA.
Zhang J; Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI, USA. .
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Źródło :
Nature ecology & evolution [Nat Ecol Evol] 2020 Dec; Vol. 4 (12), pp. 1685-1693. Date of Electronic Publication: 2020 Sep 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Epistasis, Genetic*
Genetic Fitness*
Biological Evolution ; Genotype ; Mutation
Czasopismo naukowe
Tytuł :
Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import.
Autorzy :
Girardi E; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Agrimi G; Laboratory of Biochemistry and Molecular Biology, Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari, Italy.
Goldmann U; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Fiume G; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Lindinger S; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Sedlyarov V; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Srndic I; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Gürtl B; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Agerer B; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Kartnig F; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Scarcia P; Laboratory of Biochemistry and Molecular Biology, Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari, Italy.
Di Noia MA; Laboratory of Biochemistry and Molecular Biology, Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari, Italy.
Liñeiro E; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Rebsamen M; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Wiedmer T; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Bergthaler A; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Palmieri L; Laboratory of Biochemistry and Molecular Biology, Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari, Italy.; CNR Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), Bari, Italy.
Superti-Furga G; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria. .; Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria. .
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Źródło :
Nature communications [Nat Commun] 2020 Dec 01; Vol. 11 (1), pp. 6145. Date of Electronic Publication: 2020 Dec 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epistasis, Genetic*
Mitochondria/*metabolism
NAD/*metabolism
Uncoupling Protein 1/*metabolism
Biological Transport ; Humans ; Mitochondria/genetics ; Oxidation-Reduction ; Uncoupling Protein 1/genetics
Czasopismo naukowe
Tytuł :
CGINet: graph convolutional network-based model for identifying chemical-gene interaction in an integrated multi-relational graph.
Autorzy :
Wang W; College of Computer, National University of Defense Technology, Changsha, 410073, China.
Yang X; College of Computer, National University of Defense Technology, Changsha, 410073, China.
Wu C; College of Computer, National University of Defense Technology, Changsha, 410073, China. .; State Key Laboratory of High-Performance Computing, National University of Defense Technology, Changsha, 410073, China. .
Yang C; College of Computer, National University of Defense Technology, Changsha, 410073, China.
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2020 Nov 26; Vol. 21 (1), pp. 544. Date of Electronic Publication: 2020 Nov 26.
Typ publikacji :
Journal Article
MeSH Terms :
Algorithms*
Epistasis, Genetic*
Models, Genetic*
Neural Networks, Computer*
Area Under Curve ; Gene Regulatory Networks ; Humans
Czasopismo naukowe
Tytuł :
Molecular evolutionary and structural analysis of human UCHL1 gene demonstrates the relevant role of intragenic epistasis in Parkinson's disease and other neurological disorders.
Autorzy :
Nawaz MS; National Center for Bioinformatics, Program of Comparative and Evolutionary Genomics, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
Asghar R; National Center for Bioinformatics, Program of Comparative and Evolutionary Genomics, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
Pervaiz N; National Center for Bioinformatics, Program of Comparative and Evolutionary Genomics, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
Ali S; National Center for Bioinformatics, Program of Comparative and Evolutionary Genomics, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
Hussain I; National Center for Bioinformatics, Program of Comparative and Evolutionary Genomics, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
Xing P; National Genomics Data Center & CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Bao Y; National Genomics Data Center & CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing, 100101, China. .; University of Chinese Academy of Sciences, Beijing, 100049, China. .
Abbasi AA; National Center for Bioinformatics, Program of Comparative and Evolutionary Genomics, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan. .
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Źródło :
BMC evolutionary biology [BMC Evol Biol] 2020 Oct 07; Vol. 20 (1), pp. 130. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epistasis, Genetic*
Evolution, Molecular*
Parkinson Disease*/genetics
Ubiquitin Thiolesterase/*genetics
Humans ; Phylogeny ; Ubiquitin/metabolism
Czasopismo naukowe
Tytuł :
simplePHENOTYPES: SIMulation of pleiotropic, linked and epistatic phenotypes.
Autorzy :
Fernandes SB; Department of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, 61801, USA.
Lipka AE; Department of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, 61801, USA. .
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2020 Oct 31; Vol. 21 (1), pp. 491. Date of Electronic Publication: 2020 Oct 31.
Typ publikacji :
Journal Article
MeSH Terms :
Computer Simulation*
Epistasis, Genetic*
Genetic Linkage*
Genetic Pleiotropy*
Software*
Gene Frequency/genetics ; Genome-Wide Association Study ; Genotype ; Humans ; Linkage Disequilibrium/genetics ; Multivariate Analysis ; Phenotype ; Quantitative Trait, Heritable ; Workflow
Czasopismo naukowe
Tytuł :
Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic backgrounds: Evidence for "polygenic epistasis".
Autorzy :
Rau CD; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
Gonzales NM; Department of Human Genetics, University of Chicago, Chicago, IL, United States of America.
Bloom JS; Department of Human Genetics, UCLA, Los Angeles, CA, United States of America.
Park D; Department of Medicine, UCSF, San Francisco, CA, United States of America.
Ayroles J; Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, United States of America.
Palmer AA; Department of Psychiatry, and Institute for Genomic Medicine, UCSD, San Diego, CA, United States of America.
Lusis AJ; Department of Human Genetics, UCLA, Los Angeles, CA, United States of America.
Zaitlen N; Department of Neurology, UCLA, Los Angeles, CA, United States of America.
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Źródło :
PLoS genetics [PLoS Genet] 2020 Oct 26; Vol. 16 (10), pp. e1009165. Date of Electronic Publication: 2020 Oct 26 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Epistasis, Genetic*
Evolution, Molecular*
Multifactorial Inheritance/*genetics
Selection, Genetic/*genetics
Alleles ; Animals ; Genotype ; Humans ; Mice ; Models, Genetic ; Phenotype ; Quantitative Trait Loci/genetics ; Saccharomyces cerevisiae/genetics
Czasopismo naukowe
Tytuł :
Predominance of positive epistasis among drug resistance-associated mutations in HIV-1 protease.
Autorzy :
Zhang TH; Molecular Biology Institute, University of California, Los Angeles, CA 90095, USA.
Dai L; CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Barton JP; Department of Physics and Astronomy, University of California, Riverside, CA 92521, USA.
Du Y; School of Medicine, ZheJiang University, Hangzhou, 210000, China.; Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095, USA.
Tan Y; CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Pang W; Department of Public Health Laboratory Science, West China School of Public Health, Sichuan University, Chengdu 610041, China.
Chakraborty AK; Institute for Medical Engineering and Science, Departments of Chemical Engineering, Physics, & Chemistry, Massachusetts Institute of Technology, MA 21309, USA.; Ragon Institute of MGH, MIT, & Harvard, Cambridge, MA 21309, USA.
Lloyd-Smith JO; Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA.
Sun R; Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095, USA.
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Źródło :
PLoS genetics [PLoS Genet] 2020 Oct 21; Vol. 16 (10), pp. e1009009. Date of Electronic Publication: 2020 Oct 21 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Epistasis, Genetic*
Drug Resistance, Viral/*genetics
HIV Infections/*drug therapy
HIV Protease/*genetics
HIV-1/*genetics
Genetic Fitness/genetics ; HIV Infections/genetics ; HIV Infections/virology ; HIV Protease/drug effects ; HIV-1/drug effects ; HIV-1/pathogenicity ; Humans ; Mutation/genetics ; Protease Inhibitors/adverse effects ; Protease Inhibitors/therapeutic use ; Virus Replication/drug effects ; Virus Replication/genetics
Czasopismo naukowe
Tytuł :
Unconditional and conditional analysis of epistasis between tillering QTLs based on single segment substitution lines in rice.
Autorzy :
Zhou H; Guangdong Key Lab of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China.
Yang W; Guangdong Key Lab of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China.
Ma S; Guangdong Key Lab of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China.; Guangzhou Experimental Station, Chinese Academy of Tropical Agricultural Sciences, Guangzhou, 510642, People's Republic of China.
Luan X; Guangdong Key Lab of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China.
Zhu H; Guangdong Key Lab of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China.
Wang A; Zhuhai Modern Agriculture Development Center, Zhuhai, 519000, People's Republic of China.
Huang C; Zhuhai Modern Agriculture Development Center, Zhuhai, 519000, People's Republic of China.
Rong B; Zhuhai Modern Agriculture Development Center, Zhuhai, 519000, People's Republic of China.
Dong S; Zhuhai Modern Agriculture Development Center, Zhuhai, 519000, People's Republic of China.
Meng L; Agricultural Genomics Institute in Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, 440307, People's Republic of China. .
Wang S; Guangdong Key Lab of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China. .
Zhang G; Guangdong Key Lab of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China. .
Liu G; Guangdong Key Lab of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China. .; Zhuhai Modern Agriculture Development Center, Zhuhai, 519000, People's Republic of China. .
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Źródło :
Scientific reports [Sci Rep] 2020 Sep 28; Vol. 10 (1), pp. 15912. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromosomes, Plant*
Epistasis, Genetic*
Oryza/*genetics
Phenotype ; Quantitative Trait Loci
Czasopismo naukowe
Tytuł :
Mitochondrial-nuclear coadaptation revealed through mtDNA replacements in Saccharomyces cerevisiae.
Autorzy :
Nguyen THM; Department of Biological Sciences, Binghamton University, Binghamton, NY, USA.
Sondhi S; Department of Biological Sciences, Binghamton University, Binghamton, NY, USA.
Ziesel A; Department of Biological Sciences, Binghamton University, Binghamton, NY, USA.
Paliwal S; Department of Bioscience and Biotechnology, Banasthali Vidyapith, Rajasthan, India.
Fiumera HL; Department of Biological Sciences, Binghamton University, Binghamton, NY, USA. .
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Źródło :
BMC evolutionary biology [BMC Evol Biol] 2020 Sep 25; Vol. 20 (1), pp. 128. Date of Electronic Publication: 2020 Sep 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
DNA, Mitochondrial*/genetics
Epistasis, Genetic*
Saccharomyces cerevisiae*/genetics
Cell Nucleus/*genetics
Genotype ; Mitochondria/genetics
Czasopismo naukowe
Tytuł :
Investigation of gene-gene interactions in cardiac traits and serum fatty acid levels in the LURIC Health Study.
Autorzy :
Zhou J; Department of Veterinary and Biomedical Sciences, College of Agricultural Sciences, The Pennsylvania State University, University Park, PA, United States of America.; Department of Statistics, Eberly College of Science, The Pennsylvania State University, University Park, PA, United States of America.
Passero K; Department of Veterinary and Biomedical Sciences, College of Agricultural Sciences, The Pennsylvania State University, University Park, PA, United States of America.; The Huck Institutes of the Life Science, The Pennsylvania State University, University Park, PA, United States of America.
Palmiero NE; Department of Veterinary and Biomedical Sciences, College of Agricultural Sciences, The Pennsylvania State University, University Park, PA, United States of America.
Müller-Myhsok B; Statistical Genetics, Max Planck Institute of Psychiatry, Munich, Germany.; Munich Cluster of Systems Biology, SyNergy, Munich, Germany.; Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.
Kleber ME; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Maerz W; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Synlab Holding Deutschland GmbH, SYNLAB Academy, Mannheim and Augsburg, Germany.; Medical University of Graz, Clinical Institute of Medical and Chemical Laboratory Diagnostics, Graz, Austria.
Hall MA; Department of Veterinary and Biomedical Sciences, College of Agricultural Sciences, The Pennsylvania State University, University Park, PA, United States of America.; The Huck Institutes of the Life Science, The Pennsylvania State University, University Park, PA, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Sep 11; Vol. 15 (9), pp. e0238304. Date of Electronic Publication: 2020 Sep 11 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Epistasis, Genetic*
Genetic Markers*
Polymorphism, Single Nucleotide*
Quantitative Trait Loci*
Cardiovascular Diseases/*epidemiology
Computational Biology/*methods
Fatty Acids/*blood
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Algorithms ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/genetics ; Case-Control Studies ; Female ; Follow-Up Studies ; Genome-Wide Association Study ; Germany/epidemiology ; Humans ; Male ; Middle Aged ; Phenotype ; Prognosis ; Prospective Studies ; Young Adult
Czasopismo naukowe
Tytuł :
Nonparametric analysis of casein complex genes' epistasis and their effects on phenotypic expression of milk yield and composition in Murciano-Granadina goats.
Autorzy :
Pizarro MG; Department of Genetics, University of Córdoba, Córdoba 14071, Spain.
Landi V; Animal Breeding Consulting S.L., Córdoba 14071, Spain.
Navas FJ; Department of Genetics, University of Córdoba, Córdoba 14071, Spain. Electronic address: .
León JM; Centro Agropecuario Provincial de Córdoba, Diputación Provincial de Córdoba, Córdoba 14071, Spain.
Martínez A; Department of Genetics, University of Córdoba, Córdoba 14071, Spain.
Fernández J; National Association of Breeders of Murciano-Granadina Goat Breed, Fuente Vaqueros 18340, Spain.
Delgado JV; Department of Genetics, University of Córdoba, Córdoba 14071, Spain.
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Źródło :
Journal of dairy science [J Dairy Sci] 2020 Sep; Vol. 103 (9), pp. 8274-8291. Date of Electronic Publication: 2020 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Epistasis, Genetic*
Caseins/*genetics
Goats/*genetics
Milk/*metabolism
Polymorphism, Genetic/*genetics
Animals ; Breeding ; Female ; Genotype ; Glycolipids/analysis ; Glycoproteins/analysis ; Goats/physiology ; Lactose/analysis ; Lipid Droplets ; Milk/chemistry ; Milk Proteins/analysis ; Phenotype
Czasopismo naukowe
Tytuł :
Detection of epistasis between ACTN3 and SNAP-25 with an insight towards gymnastic aptitude identification.
Autorzy :
Płóciennik ŁA; Department of Physical Education, Academy of Physical Education and Sport in Gdansk, Gdansk, Pomorskie Voivodeship, Poland.; FitnessFitback, Pomorskie Voivodeship, Poland.
Zaucha J; Department of Bioinformatics, Wissenschaftszentrum Weihenstephan, Technische Universität München, Freising, Germany.
Zaucha JM; Department of Haematology and Transplantation, Medical University of Gdansk, Gdansk, Pomorskie Voivodeship, Poland.
Łukaszuk K; Faculty of Health Sciences with Institute of Maritime and Tropical Medicine, Medical University of Gdansk, Gdansk, Pomorskie Voivodeship, Poland.
Jóźwicki M; Department of Architecture and Design, Academy of Fine Arts, Gdansk, Pomorskie Voivodeship, Poland.
Płóciennik M; FitnessFitback, Pomorskie Voivodeship, Poland.
Cięszczyk P; Department of Physical Education, Academy of Physical Education and Sport in Gdansk, Gdansk, Pomorskie Voivodeship, Poland.
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Źródło :
PloS one [PLoS One] 2020 Aug 31; Vol. 15 (8), pp. e0237808. Date of Electronic Publication: 2020 Aug 31 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aptitude*
Epistasis, Genetic*
Actinin/*genetics
Gymnastics/*physiology
Synaptosomal-Associated Protein 25/*genetics
Adult ; Alleles ; Area Under Curve ; Databases, Genetic ; Entropy ; Female ; Genetic Markers ; Humans ; Logistic Models ; Male ; Models, Genetic ; Multifactor Dimensionality Reduction ; Polymorphism, Single Nucleotide/genetics ; Young Adult
Czasopismo naukowe
Tytuł :
Epistatic interactions between killer immunoglobulin-like receptors and human leukocyte antigen ligands are associated with ankylosing spondylitis.
Autorzy :
Hanson AL; University of Queensland Diamantina Institute, University of Queensland, Brisbane, Queensland, Australia.
Vukcevic D; Melbourne Integrative Genomics, School of Mathematics and Statistics, University of Melbourne, Parkville, Victoria, Australia.; Data Science, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Leslie S; Melbourne Integrative Genomics, School of Mathematics and Statistics, University of Melbourne, Parkville, Victoria, Australia.; Data Science, Murdoch Children's Research Institute, Parkville, Victoria, Australia.; School of Biosciences, University of Melbourne, Parkville, Victoria Australia.
Harris J; Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.; Translational Research Institute, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Lê Cao KA; Melbourne Integrative Genomics, School of Mathematics and Statistics, University of Melbourne, Parkville, Victoria, Australia.
Kenna TJ; Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.; Translational Research Institute, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Brown MA; Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.; Translational Research Institute, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
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Corporate Authors :
International Genetics of Ankylosing Spondylitis Consortium
Źródło :
PLoS genetics [PLoS Genet] 2020 Aug 17; Vol. 16 (8), pp. e1008906. Date of Electronic Publication: 2020 Aug 17 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epistasis, Genetic*
HLA Antigens/*genetics
Receptors, KIR/*genetics
Spondylitis, Ankylosing/*genetics
Alleles ; Aminopeptidases/genetics ; Humans ; Minor Histocompatibility Antigens/genetics ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł :
Highly parallel lab evolution reveals that epistasis can curb the evolution of antibiotic resistance.
Autorzy :
Lukačišinová M; University of Cologne, Institute for Biological Physics, Zülpicher Straße 77, 50937, Cologne, Germany.; IST Austria, Am Campus 1, 3400, Klosterneuburg, Austria.; Department of Biology, Technion - Israel Institute of Technology, Haifa, 32000, Israel.
Fernando B; University of Cologne, Institute for Biological Physics, Zülpicher Straße 77, 50937, Cologne, Germany.
Bollenbach T; University of Cologne, Institute for Biological Physics, Zülpicher Straße 77, 50937, Cologne, Germany. .
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Źródło :
Nature communications [Nat Commun] 2020 Jun 19; Vol. 11 (1), pp. 3105. Date of Electronic Publication: 2020 Jun 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epistasis, Genetic*
Anti-Bacterial Agents/*pharmacology
Directed Molecular Evolution/*methods
Drug Resistance, Microbial/*genetics
Escherichia coli K12/*genetics
Escherichia coli K12/drug effects ; Gene Deletion ; Genes, Bacterial/genetics ; Selection, Genetic/drug effects
Czasopismo naukowe
Tytuł :
Osteoprotegerin gene polymorphisms and otosclerosis: an additional genetic association study, multilocus interaction and meta-analysis.
Autorzy :
Bouzid A; Laboratory of Molecular and Cellular Screening Processes, Centre of Biotechnology of Sfax, University of Sfax, Road Sidi Mansour Km 6, BP 1177, 3018, Sfax, Tunisia. .
Tekari A; Laboratory of Molecular and Cellular Screening Processes, Centre of Biotechnology of Sfax, University of Sfax, Road Sidi Mansour Km 6, BP 1177, 3018, Sfax, Tunisia.
Jbeli F; Laboratory of Molecular and Cellular Screening Processes, Centre of Biotechnology of Sfax, University of Sfax, Road Sidi Mansour Km 6, BP 1177, 3018, Sfax, Tunisia.
Chakroun A; Department of Otorhinolaryngology, Habib Bourguiba Teaching Hospital, University of Sfax, Avenue El Ferdaws, 3029, Sfax, Tunisia.
Hansdah K; Institute of Life Sciences, Nalco Square, Chandrasekharpur, Bhubaneswar, Odisha, 751023, India.
Souissi A; Laboratory of Molecular and Cellular Screening Processes, Centre of Biotechnology of Sfax, University of Sfax, Road Sidi Mansour Km 6, BP 1177, 3018, Sfax, Tunisia.
Singh N; Institute of Life Sciences, Nalco Square, Chandrasekharpur, Bhubaneswar, Odisha, 751023, India.
Mosrati MA; Laboratory of Molecular and Cellular Screening Processes, Centre of Biotechnology of Sfax, University of Sfax, Road Sidi Mansour Km 6, BP 1177, 3018, Sfax, Tunisia.
Achour I; Department of Otorhinolaryngology, Habib Bourguiba Teaching Hospital, University of Sfax, Avenue El Ferdaws, 3029, Sfax, Tunisia.
Ghorbel A; Department of Otorhinolaryngology, Habib Bourguiba Teaching Hospital, University of Sfax, Avenue El Ferdaws, 3029, Sfax, Tunisia.
Charfeddine I; Department of Otorhinolaryngology, Habib Bourguiba Teaching Hospital, University of Sfax, Avenue El Ferdaws, 3029, Sfax, Tunisia.
Ramchander PV; Institute of Life Sciences, Nalco Square, Chandrasekharpur, Bhubaneswar, Odisha, 751023, India.
Masmoudi S; Laboratory of Molecular and Cellular Screening Processes, Centre of Biotechnology of Sfax, University of Sfax, Road Sidi Mansour Km 6, BP 1177, 3018, Sfax, Tunisia.
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Źródło :
BMC medical genetics [BMC Med Genet] 2020 Jun 03; Vol. 21 (1), pp. 122. Date of Electronic Publication: 2020 Jun 03.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't
MeSH Terms :
Epistasis, Genetic*
Genetic Loci*
Genetic Predisposition to Disease*
Polymorphism, Single Nucleotide*
Osteoprotegerin/*genetics
Otosclerosis/*genetics
Alleles ; Case-Control Studies ; Chromosome Mapping ; Female ; Gene Frequency ; Genetic Association Studies ; Haplotypes ; Humans ; Linkage Disequilibrium ; Male ; Models, Biological ; Odds Ratio ; Otosclerosis/diagnosis
Czasopismo naukowe
Tytuł :
A parallelized strategy for epistasis analysis based on Empirical Bayesian Elastic Net models.
Autorzy :
Wen J; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
Ford CT; Department of Bioinformatics and Genomics, College of Computing and Informatics.; School of Data Science, University of North Carolina at Charlotte, Charlotte, NC 28223, USA.
Janies D; Department of Bioinformatics and Genomics, College of Computing and Informatics.
Shi X; Department of Computer and Information Sciences, Temple University, Philadelphia, PA 19122, USA.
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Źródło :
Bioinformatics (Oxford, England) [Bioinformatics] 2020 Jun 01; Vol. 36 (12), pp. 3803-3810.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Epistasis, Genetic*
Software*
Bayes Theorem ; Genomics ; Humans ; Models, Genetic ; Phenotype
Czasopismo naukowe

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