Temat: "fibrosis" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Functional Consequences of CFTR Interactions in Cystic Fibrosis.
Autorzy:: Ramananda Y; Department of Pediatrics, Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Naren AP; Department of Pediatrics, Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Arora K; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 16; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 16.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Cystic Fibrosis*/metabolism
Humans ; Cystic Fibrosis Transmembrane Conductance Regulator/metabolism ; Quality of Life ; Precision Medicine ; Signal Transduction ; Mutation

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Skocz do pozycji: 2.

Tytuł:: The Sphingolipid-Modulating Drug Opaganib Protects against Radiation-Induced Lung Inflammation and Fibrosis: Potential Uses as a Medical Countermeasure and in Cancer Radiotherapy.
Autorzy:: Maines LW; Apogee Biotechnology Corporation, 1214 Research Blvd, Suite 2015, Hummelstown, PA 17036, USA.
Keller SN; Apogee Biotechnology Corporation, 1214 Research Blvd, Suite 2015, Hummelstown, PA 17036, USA.
Smith RA; Apogee Biotechnology Corporation, 1214 Research Blvd, Suite 2015, Hummelstown, PA 17036, USA.
Green CL; Apogee Biotechnology Corporation, 1214 Research Blvd, Suite 2015, Hummelstown, PA 17036, USA.
Smith CD; Apogee Biotechnology Corporation, 1214 Research Blvd, Suite 2015, Hummelstown, PA 17036, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 15; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:: Journal Article
MeSH Terms:: Pulmonary Fibrosis*/drug therapy
Pulmonary Fibrosis*/etiology
Pulmonary Fibrosis*/pathology
Medical Countermeasures*
Pneumonia*
Neoplasms*
Pyridines*
Adamantane/*analogs & derivatives
Mice ; Animals ; Humans ; Sphingolipids/metabolism ; Fibrosis ; Inflammation/drug therapy

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Skocz do pozycji: 3.

Tytuł:: MiR-132-3p suppresses peritoneal fibrosis induced by peritoneal dialysis via targeting TGF-β1/Smad2/3 signaling pathway.
Autorzy:: Yin Y; School of Medicine, Guizhou University, Guiyang, Guizhou, China.; Department of Nephrology, Guizhou Provincial People's Hospital, Guiyang, Guizhou, China.
Yang Y; Department of Nephrology, Guizhou Provincial People's Hospital, Guiyang, Guizhou, China.
Zhang Y; Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.
Shang Y; Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.
Li Q; Department of Nephrology, Guizhou Provincial People's Hospital, Guiyang, Guizhou, China.
Yuan J; School of Medicine, Guizhou University, Guiyang, Guizhou, China.; Department of Nephrology, Guizhou Provincial People's Hospital, Guiyang, Guizhou, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Apr 11; Vol. 19 (4), pp. e0301540. Date of Electronic Publication: 2024 Apr 11 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Peritoneal Fibrosis*/genetics
Peritoneal Fibrosis*/chemically induced
Peritoneal Dialysis*/adverse effects
MicroRNAs*/genetics
Rats ; Humans ; Animals ; Transforming Growth Factor beta1/metabolism ; Rats, Sprague-Dawley ; Chlorhexidine/therapeutic use ; Losartan/therapeutic use ; Signal Transduction ; Fibrosis

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Skocz do pozycji: 4.

Tytuł:: The role of macrophage polarization and cellular crosstalk in the pulmonary fibrotic microenvironment: a review.
Autorzy:: Zhou BW; The First School of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250014, China.
Liu HM; Department of General Medicine, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250014, China.
Xu F; Department of Pneumology and Critical Care Medicine, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250014, China.
Jia XH; Department of Pneumology and Critical Care Medicine, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250014, China. jiaxinhua_.; Pokaż więcej
Źródło:: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Mar 09; Vol. 22 (1), pp. 172. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Pulmonary Fibrosis*/metabolism
Pulmonary Fibrosis*/pathology
Humans ; Fibrosis ; Macrophages/metabolism ; Cytokines/metabolism ; Signal Transduction ; Fibroblasts/metabolism

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Skocz do pozycji: 5.

Tytuł:: The Role of Lung Microbiome in Fibrotic Interstitial Lung Disease-A Systematic Review.
Autorzy:: Puiu R; Department of Medical Sciences, Pulmonology, Faculty of Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Motoc NS; Department of Medical Sciences, Pulmonology, Faculty of Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Lucaciu S; Department of Medical Sciences, Pulmonology, Faculty of Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Ruta MV; I Department of Pulmonology, 'Leon Daniello' Clinical Hospital of Pulmonology, 400371 Cluj-Napoca, Romania.
Rajnoveanu RM; Department of Palliative Medicine, Faculty of Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Todea DA; Department of Medical Sciences, Pulmonology, Faculty of Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Man MA; Department of Medical Sciences, Pulmonology, Faculty of Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2024 Feb 20; Vol. 14 (3). Date of Electronic Publication: 2024 Feb 20.
Typ publikacji:: Systematic Review; Journal Article; Review
MeSH Terms:: Lung Diseases, Interstitial*
Idiopathic Pulmonary Fibrosis*
Humans ; Disease Progression ; Lung ; Fibrosis

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Skocz do pozycji: 6.

Tytuł:: Cystic Fibrosis Mice Are Highly Susceptible to Repeated Acute Pseudomonas aeruginosa Pneumonia after Intranasal Inoculation.
Autorzy:: Manzor M; Department of Anesthesiology, Critical Care and Pain Medicine, Cardiac Anesthesia Division, Boston Children's Hospital, Boston, USA.
Koutsogiannaki S; Department of Anesthesiology, Critical Care and Pain Medicine, Cardiac Anesthesia Division, Boston Children's Hospital, Boston, USA.; Department of Anaesthesia, Harvard Medical School, Boston, USA.; Department of Immunology, Harvard Medical School, Boston, USA.; Broad Institute of MIT and Harvard, Cambridge, USA.
DiBlasi M; Department of Anesthesiology, Critical Care and Pain Medicine, Critical Care Division, Boston Children's Hospital, Boston, USA.
Schaefers M; Department of Anaesthesia, Harvard Medical School, Boston, USA.; Department of Anesthesiology, Critical Care and Pain Medicine, Critical Care Division, Boston Children's Hospital, Boston, USA.
Priebe G; Department of Anaesthesia, Harvard Medical School, Boston, USA.; Broad Institute of MIT and Harvard, Cambridge, USA.; Department of Anesthesiology, Critical Care and Pain Medicine, Critical Care Division, Boston Children's Hospital, Boston, USA.; Department of Pediatrics, Division of Infectious Diseases, Boston Children's Hospital, Boston, USA.
Yuki K; Department of Anesthesiology, Critical Care and Pain Medicine, Cardiac Anesthesia Division, Boston Children's Hospital, Boston, USA.; Department of Anaesthesia, Harvard Medical School, Boston, USA.; Department of Immunology, Harvard Medical School, Boston, USA.; Broad Institute of MIT and Harvard, Cambridge, USA.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2024 Feb 05; Vol. 2024, pp. 4769779. Date of Electronic Publication: 2024 Feb 05 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Cystic Fibrosis*/genetics
Cystic Fibrosis*/microbiology
Pneumonia*/complications
Pseudomonas Infections*/microbiology
Humans ; Mice ; Animals ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Pseudomonas aeruginosa ; Persistent Infection ; Mice, Transgenic

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Skocz do pozycji: 7.

Tytuł:: Pulmonary Pathology Society Survey on Practice Approaches in the Histologic Diagnosis of Fibrotic Interstitial Lung Disease: Consensus and Opportunities.
Autorzy:: Smith ML; From the Departments of Laboratory Medicine and Pathology (Smith, Colby).
Mino-Kenudson M; the Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston (Mino-Kenudson, Hariri).
Butterfield RJ; Quantitative Health Sciences (Butterfield), Mayo Clinic Arizona, Scottsdale.
Dacic S; the Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (Dacic).
Colby TV; From the Departments of Laboratory Medicine and Pathology (Smith, Colby).
Churg A; the Department of Pathology, Vancouver General Hospital, Vancouver, British Columbia, Canada (Churg).
Beasley MB; the Department of Pathology, Mount Sinai Health System, Icahn School of Medicine, New York, New York (Beasley).
Hariri LP; the Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston (Mino-Kenudson, Hariri).; Pokaż więcej
Źródło:: Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2024 Feb 01; Vol. 148 (2), pp. 168-177.
Typ publikacji:: Journal Article
MeSH Terms:: Lung Diseases, Interstitial*/diagnosis
Lung Diseases, Interstitial*/pathology
Idiopathic Pulmonary Fibrosis*/diagnosis
Idiopathic Pulmonary Fibrosis*/pathology
Humans ; Consensus ; Tomography, X-Ray Computed/methods ; Lung/diagnostic imaging ; Lung/pathology ; Fibrosis

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Skocz do pozycji: 8.

Tytuł:: Insights into Disease Progression of Translational Preclinical Rat Model of Interstitial Pulmonary Fibrosis through Endpoint Analysis.
Autorzy:: Kadam AH; Proteogenomics Research Institute for Systems Medicine (PRISM), 505 Coast Blvd. South, La Jolla, CA 92037, USA.
Schnitzer JE; Proteogenomics Research Institute for Systems Medicine (PRISM), 505 Coast Blvd. South, La Jolla, CA 92037, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Mar 15; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:: Journal Article
MeSH Terms:: Procollagen*
Idiopathic Pulmonary Fibrosis*/pathology
Rats ; Humans ; Animals ; Fibrosis ; Collagen/metabolism ; Bleomycin ; Disease Progression

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Skocz do pozycji: 9.

Tytuł:: OrgaSegment: deep-learning based organoid segmentation to quantify CFTR dependent fluid secretion.
Autorzy:: Lefferts JW; Department of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, 3584 EA, Utrecht, The Netherlands.; Regenerative Medicine Utrecht, University Medical Center, Utrecht University, 3584 CT, Utrecht, The Netherlands.
Kroes S; Department of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, 3584 EA, Utrecht, The Netherlands.; Regenerative Medicine Utrecht, University Medical Center, Utrecht University, 3584 CT, Utrecht, The Netherlands.
Smith MB; Department of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, 3584 EA, Utrecht, The Netherlands.; Regenerative Medicine Utrecht, University Medical Center, Utrecht University, 3584 CT, Utrecht, The Netherlands.; Centre for Living Technologies, Alliance TU/e, WUR, UU, UMC Utrecht, 3584 CB, Utrecht, The Netherlands.
Niemöller PJ; Department of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, 3584 EA, Utrecht, The Netherlands.; Regenerative Medicine Utrecht, University Medical Center, Utrecht University, 3584 CT, Utrecht, The Netherlands.
Nieuwenhuijze NDA; Department of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, 3584 EA, Utrecht, The Netherlands.; Regenerative Medicine Utrecht, University Medical Center, Utrecht University, 3584 CT, Utrecht, The Netherlands.; Centre for Living Technologies, Alliance TU/e, WUR, UU, UMC Utrecht, 3584 CB, Utrecht, The Netherlands.
Sonneveld van Kooten HN; Department of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, 3584 EA, Utrecht, The Netherlands.; Regenerative Medicine Utrecht, University Medical Center, Utrecht University, 3584 CT, Utrecht, The Netherlands.; Centre for Living Technologies, Alliance TU/e, WUR, UU, UMC Utrecht, 3584 CB, Utrecht, The Netherlands.
van der Ent CK; Department of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, 3584 EA, Utrecht, The Netherlands.
Beekman JM; Department of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, 3584 EA, Utrecht, The Netherlands. .; Regenerative Medicine Utrecht, University Medical Center, Utrecht University, 3584 CT, Utrecht, The Netherlands. .; Centre for Living Technologies, Alliance TU/e, WUR, UU, UMC Utrecht, 3584 CB, Utrecht, The Netherlands. .
van Beuningen SFB; Department of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, 3584 EA, Utrecht, The Netherlands. .; Regenerative Medicine Utrecht, University Medical Center, Utrecht University, 3584 CT, Utrecht, The Netherlands. .; Centre for Living Technologies, Alliance TU/e, WUR, UU, UMC Utrecht, 3584 CB, Utrecht, The Netherlands. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2024 Mar 13; Vol. 7 (1), pp. 319. Date of Electronic Publication: 2024 Mar 13.
Typ publikacji:: Journal Article
MeSH Terms:: Deep Learning*
Cystic Fibrosis*/genetics
Humans ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Intestines ; Organoids

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Skocz do pozycji: 10.

Tytuł:: NXC736 Attenuates Radiation-Induced Lung Fibrosis via Regulating NLRP3/IL-1β Signaling Pathway.
Autorzy:: Kim SY; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Park S; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Cui R; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Lee H; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Choi H; Nextgen Bioscience, Bundang-gu, Seongnam-si 13487, Gyeonggi-do, Republic of Korea.
Farh ME; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Jo HI; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Lee JH; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Song HJ; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Lee YJ; Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.
Lee YS; Graduate School of Pharmaceutical Sciences and College of Pharmacy, Ewha Womans University, Seoul 03760, Republic of Korea.
Lee BY; Nextgen Bioscience, Bundang-gu, Seongnam-si 13487, Gyeonggi-do, Republic of Korea.
Cho J; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 13; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:: Journal Article
MeSH Terms:: Pulmonary Fibrosis*/drug therapy
Pulmonary Fibrosis*/etiology
Pulmonary Fibrosis*/metabolism
Radiation Injuries*/metabolism
Mice ; Animals ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Lung/pathology ; Fibrosis ; Inflammasomes/metabolism ; Signal Transduction ; Radiation Fibrosis Syndrome

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Skocz do pozycji: 11.

Tytuł:: Antifibrotic Drugs against Idiopathic Pulmonary Fibrosis and Pulmonary Fibrosis Induced by COVID-19: Therapeutic Approaches and Potential Diagnostic Biomarkers.
Autorzy:: Perez-Favila A; Doctorado en Ciencias con Orientación en Medicina Molecular, Unidad Académica de Medicina Humana y CS, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.
Garza-Veloz I; Doctorado en Ciencias con Orientación en Medicina Molecular, Unidad Académica de Medicina Humana y CS, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.
Hernandez-Marquez LDS; Doctorado en Ciencias con Orientación en Medicina Molecular, Unidad Académica de Medicina Humana y CS, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.
Gutierrez-Vela EF; Doctorado en Ciencias con Orientación en Medicina Molecular, Unidad Académica de Medicina Humana y CS, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.
Flores-Morales V; Doctorado en Ciencias con Orientación en Medicina Molecular, Unidad Académica de Medicina Humana y CS, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.
Martinez-Fierro ML; Doctorado en Ciencias con Orientación en Medicina Molecular, Unidad Académica de Medicina Humana y CS, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 26; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:: Journal Article; Review
MeSH Terms:: COVID-19*/complications
Idiopathic Pulmonary Fibrosis*/diagnosis
Idiopathic Pulmonary Fibrosis*/drug therapy
Idiopathic Pulmonary Fibrosis*/etiology
Humans ; Pandemics ; Fibrosis ; Biomarkers ; COVID-19 Testing

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Skocz do pozycji: 12.

Tytuł:: Evaluation of the efficiency of nanomicellar formulation of fat-soluble vitamins in patients with cystic fibrosis: the study protocol for a randomized controlled trial.
Autorzy:: Soleimanzadeh M; Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Talebi S; Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. .
Jaafari MR; Nanotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Sayedi SJ; Department of Pediatrics, Mashhad University of Medical Sciences, Mashhad, Iran.
Emadzadeh M; Clinical Research Development Unit, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Kianifar HR; Department of Pediatrics, Mashhad University of Medical Sciences, Mashhad, Iran.; Pokaż więcej
Źródło:: Trials [Trials] 2024 Jan 16; Vol. 25 (1), pp. 60. Date of Electronic Publication: 2024 Jan 16.
Typ publikacji:: Clinical Trial Protocol; Journal Article
MeSH Terms:: Cystic Fibrosis*/diagnosis
Cystic Fibrosis*/drug therapy
Child ; Humans ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Quality of Life ; Iran ; Prospective Studies ; Single-Blind Method ; Dietary Supplements ; Vitamins/therapeutic use ; Vitamin A ; Vitamin K ; Randomized Controlled Trials as Topic

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Skocz do pozycji: 13.

Tytuł:: Traditional Chinese medicine inspired dual-drugs loaded inhalable nano-therapeutics alleviated idiopathic pulmonary fibrosis by targeting early inflammation and late fibrosis.
Autorzy:: Zheng M; Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100010, China.; Peking University People's Hospital, Beijing, 100032, China.
Liu K; Division of Pulmonary and Critical Care Medicine, Kunming Children's Hospital, Kunming, 650000, China.
Li L; Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, National Clinical Research Center for Obstetric & Gynecologic Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100032, China. .
Feng C; Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100010, China. .; Peking University People's Hospital, Beijing, 100032, China. .
Wu G; School of Materials Science & Engineering, Beijing Institute of Technology, Beijing, 100081, China. .; Pokaż więcej
Źródło:: Journal of nanobiotechnology [J Nanobiotechnology] 2024 Jan 03; Vol. 22 (1), pp. 14. Date of Electronic Publication: 2024 Jan 03.
Typ publikacji:: Journal Article
MeSH Terms:: NLR Family, Pyrin Domain-Containing 3 Protein*
Idiopathic Pulmonary Fibrosis*/drug therapy
Idiopathic Pulmonary Fibrosis*/chemically induced
Idiopathic Pulmonary Fibrosis*/metabolism
Humans ; Medicine, Chinese Traditional ; Inflammasomes/metabolism ; Reactive Oxygen Species/metabolism ; Quality of Life ; Lung/metabolism ; Fibrosis ; Inflammation/pathology ; p38 Mitogen-Activated Protein Kinases

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Skocz do pozycji: 14.

Tytuł:: Exploring the Mechanism of Activation of CFTR by Curcuminoids: An Ensemble Docking Study.
Autorzy:: Bellacchio E; Genetica Molecolare e Genomica Funzionale, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 31; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 31.
Typ publikacji:: Journal Article
MeSH Terms:: Curcumin*/pharmacology
Cystic Fibrosis*
Humans ; Diarylheptanoids ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Nucleotides ; Adenosine Triphosphate

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Skocz do pozycji: 15.

Tytuł:: The Plastic Interplay between Lung Regeneration Phenomena and Fibrotic Evolution: Current Challenges and Novel Therapeutic Perspectives.
Autorzy:: Lettieri S; Department of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy.; Cardiothoracic and Vascular Department, Unit of Respiratory Diseases, IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Bertuccio FR; Department of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy.; Cardiothoracic and Vascular Department, Unit of Respiratory Diseases, IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Del Frate L; Department of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy.; Cardiothoracic and Vascular Department, Unit of Respiratory Diseases, IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Perrotta F; Department of Translational Medical Science, University of Campania Luigi Vanvitelli, 80055 Naples, Italy.
Corsico AG; Department of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy.; Cardiothoracic and Vascular Department, Unit of Respiratory Diseases, IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Stella GM; Department of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy.; Cardiothoracic and Vascular Department, Unit of Respiratory Diseases, IRCCS Policlinico San Matteo, 27100 Pavia, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 31; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 31.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Idiopathic Pulmonary Fibrosis*/etiology
Idiopathic Pulmonary Fibrosis*/genetics
Pulmonary Surfactants*
COVID-19*
Humans ; Alveolar Epithelial Cells ; Fibrosis

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Skocz do pozycji: 16.

Tytuł:: Longitudinal microbial and molecular dynamics in the cystic fibrosis lung after Elexacaftor-Tezacaftor-Ivacaftor therapy.
Autorzy:: Martin C; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, USA.
Guzior DV; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, USA.; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI, USA.
Gonzalez CT; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, USA.
Okros M; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, USA.
Mielke J; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
Padillo L; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
Querido G; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
Gil M; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
Thomas R; Department of Pediatrics and Human Development, Michigan State University, East Lansing, MI, USA.
McClelland M; Corewell Health, Grand Rapids, MI, USA.
Conrad D; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
Widder S; Department of Medicine, Research Division Infection Biology, Medical University of Vienna, Vienna, Austria.
Quinn RA; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, USA. .; Pokaż więcej
Źródło:: Respiratory research [Respir Res] 2023 Dec 16; Vol. 24 (1), pp. 317. Date of Electronic Publication: 2023 Dec 16.
Typ publikacji:: Journal Article
MeSH Terms:: Cystic Fibrosis*/diagnosis
Cystic Fibrosis*/drug therapy
Cystic Fibrosis*/genetics
Humans ; Molecular Dynamics Simulation ; RNA, Ribosomal, 16S ; Lung ; Cystic Fibrosis Transmembrane Conductance Regulator ; Mutation

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Skocz do pozycji: 17.

Tytuł:: In vitro co-culture studies and the crucial role of fibroblast-immune cell crosstalk in IPF pathogenesis.
Autorzy:: Thiam F; Department of Biology, University of British Columbia, 3187 University Way, ASC366, Kelowna, BC, V1V1V7, Canada.
Phogat S; Department of Biology, University of British Columbia, 3187 University Way, ASC366, Kelowna, BC, V1V1V7, Canada.
Abokor FA; Department of Biology, University of British Columbia, 3187 University Way, ASC366, Kelowna, BC, V1V1V7, Canada.
Osei ET; Department of Biology, University of British Columbia, 3187 University Way, ASC366, Kelowna, BC, V1V1V7, Canada. .; Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC, Canada. .; Pokaż więcej
Źródło:: Respiratory research [Respir Res] 2023 Nov 27; Vol. 24 (1), pp. 298. Date of Electronic Publication: 2023 Nov 27.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Idiopathic Pulmonary Fibrosis*/metabolism
Humans ; Coculture Techniques ; Lung/metabolism ; Fibroblasts/metabolism ; Fibrosis

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Skocz do pozycji: 18.

Tytuł:: Monoclonal enolase-1 blocking antibody ameliorates pulmonary inflammation and fibrosis.
Autorzy:: Huang WC; HuniLife Biotechnology Inc, Taipei, Taiwan.
Chuang CF; HuniLife Biotechnology Inc, Taipei, Taiwan.
Huang YT; HuniLife Biotechnology Inc, Taipei, Taiwan.
Chung IC; HuniLife Biotechnology Inc, Taipei, Taiwan.
Chen ML; HuniLife Biotechnology Inc, Taipei, Taiwan.
Chuang TY; HuniLife Biotechnology Inc, Taipei, Taiwan.
Yang XL; HuniLife Biotechnology Inc, Taipei, Taiwan.
Chou YY; HuniLife Biotechnology Inc, Taipei, Taiwan.
Liu CH; HuniLife Biotechnology Inc, Taipei, Taiwan.
Chen NY; Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei, Taiwan.
Chen CJ; Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei, Taiwan.
Yuan TT; HuniLife Biotechnology Inc, Taipei, Taiwan. .; Department of Research and Development, HuniLife Biotechnology Inc, Rm. 1, 6F., No. 308, Sec. 1, Neihu Rd., Neihu Dist, 114, Taipei City, Taiwan. .; Pokaż więcej
Źródło:: Respiratory research [Respir Res] 2023 Nov 14; Vol. 24 (1), pp. 280. Date of Electronic Publication: 2023 Nov 14.
Typ publikacji:: Journal Article
MeSH Terms:: Idiopathic Pulmonary Fibrosis*/chemically induced
Idiopathic Pulmonary Fibrosis*/drug therapy
Idiopathic Pulmonary Fibrosis*/metabolism
Pneumonia*/metabolism
Mice ; Humans ; Animals ; Leukocytes, Mononuclear/metabolism ; Antibodies, Monoclonal/therapeutic use ; Endothelial Cells/metabolism ; Fibrinolysin/metabolism ; Fibrinolysin/pharmacology ; Fibrinolysin/therapeutic use ; Lung/metabolism ; Fibrosis ; Collagen/metabolism ; Bleomycin/toxicity ; Fibroblasts/metabolism ; Phosphopyruvate Hydratase/metabolism ; Phosphopyruvate Hydratase/pharmacology ; Phosphopyruvate Hydratase/therapeutic use ; Mice, Inbred C57BL

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Tytuł:: A Novel Co-Culture Model Reveals Enhanced CFTR Rescue in Primary Cystic Fibrosis Airway Epithelial Cultures with Persistent Pseudomonas aeruginosa Infection.
Autorzy:: Cholon DM; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
Greenwald MA; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27599, USA.
Higgs MG; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27599, USA.
Quinney NL; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
Boyles SE; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
Meinig SL; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Pharmaceutical Product Development (PPD), Thermo Fisher Scientific, Morrisville, NC 27560, USA.
Minges JT; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
Chaubal A; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
Tarran R; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Division of Genetic, Department of Internal Medicine, Environmental and Inhalational Disease, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Ribeiro CMP; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Division of Pulmonary Diseases, Department of Medicine, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Department of Cell Biology and Physiology, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
Wolfgang MC; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27599, USA.
Gentzsch M; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Department of Cell Biology and Physiology, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Division of Pediatric Pulmonology, Department of Pediatrics, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Nov 13; Vol. 12 (22). Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cystic Fibrosis*/metabolism
Pseudomonas Infections*/drug therapy
Pseudomonas Infections*/microbiology
Humans ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Cystic Fibrosis Transmembrane Conductance Regulator/metabolism ; Coculture Techniques ; Lung/metabolism

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Tytuł:: The impact of SARS-CoV-2 infection in patients with cystic fibrosis undergoing CFTR channel modulators treatment: a literature review.
Autorzy:: Vitiello A; Directorate General for Health Prevention, Ministry of Health, Rome, Italy.
Sabbatucci M; Directorate General for Health Prevention, Ministry of Health, Rome, Italy.; Department Infectious Diseases, National Institute of Health, Rome, Italy.
Silenzi A; Directorate General for Health Prevention, Ministry of Health, Rome, Italy.
Capuano A; Section of Pharmacology 'L. Donatelli', Department of Experimental Medicine, Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, University of Campania 'Luigi Vanvitelli', Naples, Italy.
Rossi F; Section of Pharmacology 'L. Donatelli', Department of Experimental Medicine, Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, University of Campania 'Luigi Vanvitelli', Naples, Italy.
Zovi A; Directorate General for Hygiene, Food Safety and Nutrition, Ministry of Health, Rome, Italy. .
Blasi F; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy. .; Internal Medicine Department, Respiratory Unit and Cystic Fibrosis Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. .
Rezza G; Directorate General for Health Prevention, Ministry of Health, Rome, Italy.; Pokaż więcej
Źródło:: Respiratory research [Respir Res] 2023 Nov 13; Vol. 24 (1), pp. 278. Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Cystic Fibrosis*/drug therapy
Cystic Fibrosis*/metabolism
COVID-19*
Humans ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; RNA, Viral ; SARS-CoV-2

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