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Wyświetlanie 1-20 z 22875
Tytuł:
Increase of liver stiffness and altered bile acid metabolism after triple CFTR modulator initiation in children and young adults with cystic fibrosis.
Autorzy:
Schnell A; Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Jüngert J; Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Klett D; Department of Medicine 1 and German Center Immunotherapy (DZI), University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Hober H; Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Kaiser N; Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Ruppel R; Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Geppert A; Department of Medicine 1 and German Center Immunotherapy (DZI), University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Tremel C; Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Sobel J; Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Plattner E; Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Schmitt-Grohé S; Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Zirlik S; Department of Medicine 1 and German Center Immunotherapy (DZI), University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Strobel D; Department of Medicine 1 and German Center Immunotherapy (DZI), University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Neurath MF; Department of Medicine 1 and German Center Immunotherapy (DZI), University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Knieling F; Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.; Translational Experimental and Molecular Imaging Laboratory (PETI_Lab), Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Rauh M; Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Woelfle J; Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Hoerning A; Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Regensburger AP; Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.; Translational Experimental and Molecular Imaging Laboratory (PETI_Lab), Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
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Źródło:
Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2023 Apr; Vol. 43 (4), pp. 878-887. Date of Electronic Publication: 2023 Feb 28.
Typ publikacji:
Observational Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cystic Fibrosis*/drug therapy
Cystic Fibrosis*/complications
Elasticity Imaging Techniques*/methods
Humans ; Child ; Young Adult ; Adult ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Cognition ; Liver/diagnostic imaging ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Sirt1 overexpression improves senescence-associated pulmonary fibrosis induced by vitamin D deficiency through downregulating IL-11 transcription.
Autorzy:
Zhou J; Department of Human Anatomy, Research Centre for Bone and Stem Cells, Key Laboratory for Aging & Disease, The State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Chen H; Anti-Aging Research Laboratory, Friendship Plastic Surgery Hospital, Nanjing Medical University, Nanjing, China.
Wang Q; Department of Human Anatomy, Research Centre for Bone and Stem Cells, Key Laboratory for Aging & Disease, The State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Chen S; Department of Human Anatomy, Research Centre for Bone and Stem Cells, Key Laboratory for Aging & Disease, The State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Wang R; Department of Human Anatomy, Research Centre for Bone and Stem Cells, Key Laboratory for Aging & Disease, The State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Wang Z; Department of Human Anatomy, Research Centre for Bone and Stem Cells, Key Laboratory for Aging & Disease, The State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Yang C; Department of Human Anatomy, Research Centre for Bone and Stem Cells, Key Laboratory for Aging & Disease, The State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Chen A; Department of Human Anatomy, Research Centre for Bone and Stem Cells, Key Laboratory for Aging & Disease, The State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Zhao J; Department of Human Anatomy, Research Centre for Bone and Stem Cells, Key Laboratory for Aging & Disease, The State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Zhou Z; Department of Human Anatomy, Research Centre for Bone and Stem Cells, Key Laboratory for Aging & Disease, The State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Mao Z; Department of Human Anatomy, Research Centre for Bone and Stem Cells, Key Laboratory for Aging & Disease, The State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Zuo G; Department of Human Anatomy, Research Centre for Bone and Stem Cells, Key Laboratory for Aging & Disease, The State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.; The Laboratory Centre for Basic Medical Sciences, Nanjing Medical University, Nanjing, China.
Miao D; Department of Human Anatomy, Research Centre for Bone and Stem Cells, Key Laboratory for Aging & Disease, The State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.; Anti-Aging Research Laboratory, Friendship Plastic Surgery Hospital, Nanjing Medical University, Nanjing, China.
Jin J; Department of Human Anatomy, Research Centre for Bone and Stem Cells, Key Laboratory for Aging & Disease, The State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
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Źródło:
Aging cell [Aging Cell] 2022 Aug; Vol. 21 (8), pp. e13680. Date of Electronic Publication: 2022 Jul 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Pulmonary Fibrosis*/chemically induced
Pulmonary Fibrosis*/genetics
Vitamin D Deficiency*/complications
Vitamin D Deficiency*/genetics
Interleukin-11/*metabolism
Sirtuin 1/*metabolism
25-Hydroxyvitamin D3 1-alpha-Hydroxylase ; Animals ; Fibrosis ; Mice ; Mitogen-Activated Protein Kinase Kinases/adverse effects ; Sirtuin 1/genetics ; Transforming Growth Factor beta1/metabolism ; Vitamin D
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mitochondrial uncoupling protein-2 reprograms metabolism to induce oxidative stress and myofibroblast senescence in age-associated lung fibrosis.
Autorzy:
Rangarajan S; Division of Pulmonary Sciences and Critical Care, Department of Medicine, University of Colorado, Aurora, Colorado, USA.
Locy ML; Division of Pulmonary and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Chanda D; Division of Pulmonary and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Kurundkar A; Division of Pulmonary and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Kurundkar D; Division of Pulmonary and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Larson-Casey JL; Division of Pulmonary and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Londono P; Division of Pulmonary Sciences and Critical Care, Department of Medicine, University of Colorado, Aurora, Colorado, USA.
Bagchi RA; Division of Cardiology, Department of Medicine, University of Colorado, Aurora, Colorado, USA.
Deskin B; Division of Pulmonary and Critical Care, Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Elajaili H; Cardiovascular Pulmonary Research Laboratories and Pediatric Critical Care Medicine, Department of Pediatrics, University of Colorado, Aurora, Colorado, USA.
Nozik ES; Cardiovascular Pulmonary Research Laboratories and Pediatric Critical Care Medicine, Department of Pediatrics, University of Colorado, Aurora, Colorado, USA.
Deshane JS; Division of Pulmonary and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Zmijewski JW; Division of Pulmonary and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Eickelberg O; Division of Pulmonary, Allergy and Critical Care, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Thannickal VJ; John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA.
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Źródło:
Aging cell [Aging Cell] 2022 Sep; Vol. 21 (9), pp. e13674. Date of Electronic Publication: 2022 Aug 07.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Idiopathic Pulmonary Fibrosis*/metabolism
Myofibroblasts*/metabolism
Uncoupling Protein 2*/genetics
Uncoupling Protein 2*/metabolism
Aged ; Animals ; Fibroblasts/metabolism ; Fibrosis ; Humans ; Lung/metabolism ; Mice ; Oxidative Stress ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Natural Small Molecule Mitigates Kidney Fibrosis by Targeting Cdc42‐mediated GSK‐3β/β‐catenin Signaling.
Autorzy:
Hu, Xinrong (AUTHOR)
Gan, Lu (AUTHOR)
Tang, Ziwen (AUTHOR)
Lin, Ruoni (AUTHOR)
Liang, Zhou (AUTHOR)
Li, Feng (AUTHOR)
Zhu, Changjian (AUTHOR)
Han, Xu (AUTHOR)
Zheng, Ruilin (AUTHOR)
Shen, Jiani (AUTHOR)
Yu, Jing (AUTHOR)
Luo, Ning (AUTHOR)
Peng, Wenxing (AUTHOR)
Tan, Jiaqing (AUTHOR)
Li, Xiaoyan (AUTHOR)
Fan, Jinjin (AUTHOR)
Wen, Qiong (AUTHOR)
Wang, Xin (AUTHOR)
Li, Jianbo (AUTHOR)
Zheng, Xunhua (AUTHOR)
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Źródło:
Advanced Science. 4/3/2024, Vol. 11 Issue 13, p1-21. 21p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Protozoan‐Derived Cytokine‐Transgenic Macrophages Reverse Hepatic Fibrosis.
Autorzy:
Chen, Ying (AUTHOR)
Wang, Jie (AUTHOR)
Zhou, Nan (AUTHOR)
Fang, Qi (AUTHOR)
Cai, Haijian (AUTHOR)
Du, Zhuoran (AUTHOR)
An, Ran (AUTHOR)
Liu, Deng (AUTHOR)
Chen, Xuepeng (AUTHOR)
Wang, Xinxin (AUTHOR)
Li, Fangmin (AUTHOR)
Yan, Qi (AUTHOR)
Chen, Lijian (AUTHOR)
Du, Jian (AUTHOR)
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Źródło:
Advanced Science. 4/3/2024, Vol. 11 Issue 13, p1-17. 17p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Investigation of the effects of white tea on liver fibrosis: An experimental animal model.
Autorzy:
Yılmaz, Hülya Kılıç (AUTHOR)
Türker, Merve (AUTHOR)
Kutlu, Eda Yılmaz (AUTHOR)
Mercantepe, Tolga (AUTHOR)
Pınarbaş, Esra (AUTHOR)
Tümkaya, Levent (AUTHOR)
Atak, Mehtap (AUTHOR)
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Źródło:
Food Science & Nutrition. Apr2024, Vol. 12 Issue 4, p2998-3006. 9p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Physiologically‐based pharmacokinetic modeling of the drug–drug interaction between ivacaftor and lefamulin in cystic fibrosis patients.
Autorzy:
Amiel, Magali (AUTHOR)
Ke, Alice (AUTHOR)
Gelone, Steven P. (AUTHOR)
Jones, Hannah M. (AUTHOR)
Wicha, Wolfgang (AUTHOR)
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Źródło:
CPT: Pharmacometrics & Systems Pharmacology. Apr2024, Vol. 13 Issue 4, p589-598. 10p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Natural intestinal metabolite xylitol reduces BRD4 levels to mitigate renal fibrosis.
Autorzy:
Tan, Zhouke (AUTHOR)
Wang, Ze (AUTHOR)
Zeng, Qianglin (AUTHOR)
Liu, Xiaoyou (AUTHOR)
Zhang, Yamei (AUTHOR)
Li, Shujue (AUTHOR)
Huang, Junlin (AUTHOR)
Zeng, Yunong (AUTHOR)
Huang, Zongshun (AUTHOR)
Jin, Can (AUTHOR)
Fu, Ningying (AUTHOR)
Zhao, Qian (AUTHOR)
Mu, Yingsong (AUTHOR)
Wang, Ziyi (AUTHOR)
Xiao, Jie (AUTHOR)
Yang, Hong (AUTHOR)
Ke, Guibao (AUTHOR)
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Źródło:
CTS: Clinical & Translational Science. Mar2024, Vol. 17 Issue 3, p1-14. 14p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Discovery of PRDM16‐Mediated TRPA1 Induction as the Mechanism for Low Tubulo‐Interstitial Fibrosis in Diabetic Kidney Disease.
Autorzy:
Xu, Fang (AUTHOR)
Jiang, Hongwei (AUTHOR)
Li, Xiaozhou (AUTHOR)
Pan, Jian (AUTHOR)
Li, Huiling (AUTHOR)
Wang, Luxiang (AUTHOR)
Zhang, Pan (AUTHOR)
Chen, Junxiang (AUTHOR)
Qiu, Shuangfa (AUTHOR)
Xie, Yuxin (AUTHOR)
Li, Yijian (AUTHOR)
Zhang, Dongshan (AUTHOR)
Dong, Zheng (AUTHOR)
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Źródło:
Advanced Science. 2/16/2024, Vol. 11 Issue 7, p1-17. 17p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An Autologous Macrophage‐Based Phenotypic Transformation‐Collagen Degradation System Treating Advanced Liver Fibrosis.
Autorzy:
Duan, Bo‐Wen (AUTHOR)
Liu, Yan‐Jun (AUTHOR)
Li, Xue‐Na (AUTHOR)
Han, Meng‐Meng (AUTHOR)
Yu, Hao‐Yuan (AUTHOR)
Hong, He‐Yuan (AUTHOR)
Zhang, Ling‐Feng (AUTHOR)
Xing, Lei (AUTHOR)
Jiang, Hu‐Lin (AUTHOR)
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Źródło:
Advanced Science. 2/16/2024, Vol. 11 Issue 7, p1-15. 15p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pericardial delta like non‐canonical NOTCH ligand 1 (Dlk1) augments fibrosis in the heart through epithelial to mesenchymal transition.
Autorzy:
Jensen, Charlotte Harken (AUTHOR)
Johnsen, Rikke Helin (AUTHOR)
Eskildsen, Tilde (AUTHOR)
Baun, Christina (AUTHOR)
Ellman, Ditte Gry (AUTHOR)
Fang, Shu (AUTHOR)
Bak, Sara Thornby (AUTHOR)
Hvidsten, Svend (AUTHOR)
Larsen, Lars Allan (AUTHOR)
Rosager, Ann Mari (AUTHOR)
Riber, Lars Peter (AUTHOR)
Schneider, Mikael (AUTHOR)
De Mey, Jo (AUTHOR)
Thomassen, Mads (AUTHOR)
Burton, Mark (AUTHOR)
Uchida, Shizuka (AUTHOR)
Laborda, Jorge (AUTHOR)
Andersen, Ditte Caroline (AUTHOR)
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Źródło:
Clinical & Translational Medicine. Feb2024, Vol. 14 Issue 2, p1-18. 18p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pyruvate kinase M2 regulates kidney fibrosis through pericyte glycolysis during the progression from acute kidney injury to chronic kidney disease.
Autorzy:
Chen, Yulan (AUTHOR)
Bai, Xueyuan (AUTHOR)
Chen, Jianwen (AUTHOR)
Huang, Mengjie (AUTHOR)
Hong, Quan (AUTHOR)
Ouyang, Qing (AUTHOR)
Sun, Xuefeng (AUTHOR)
Zhang, Yan (AUTHOR)
Liu, Jiaona (AUTHOR)
Wang, Xu (AUTHOR)
Wu, Lingling (AUTHOR)
Chen, Xiangmei (AUTHOR)
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Źródło:
Cell Proliferation. Feb2024, Vol. 57 Issue 2, p1-13. 13p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Phosphodiesterase inhibitor ameliorates senescent changes of renal interstitial pericytes in aging kidney.
Autorzy:
Kim HD; Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Kim EN; Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Lim JH; Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Kim Y; Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Ban TH; Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Lee H; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Kim YS; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Park CW; Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Choi BS; Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
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Źródło:
Aging cell [Aging Cell] 2024 Mar; Vol. 23 (3), pp. e14075. Date of Electronic Publication: 2023 Dec 28.
Typ publikacji:
Journal Article
MeSH Terms:
Pericytes*/metabolism
Kidney Diseases*/metabolism
Humans ; Mice ; Animals ; Aged ; Phosphodiesterase Inhibitors/metabolism ; Endothelial Cells/metabolism ; Albuminuria/metabolism ; Albuminuria/pathology ; Mice, Inbred C57BL ; Kidney/metabolism ; Aging ; Fibrosis ; Inflammation/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
P2X7 accelerate tissue fibrosis via metalloproteinase 8‐dependent macrophage infiltration in a murine model of unilateral ureteral obstruction.
Autorzy:
Therkildsen, Jacob Rudjord (AUTHOR)
Tingskov, Stine Julie (AUTHOR)
Jensen, Michael Schou (AUTHOR)
Praetorius, Helle (AUTHOR)
Nørregaard, Rikke (AUTHOR)
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Źródło:
Physiological Reports. Nov2023, Vol. 11 Issue 22, p1-17. 17p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Idiopathic pulmonary fibrosis: Addressing the current and future therapeutic advances along with the role of Sotatercept in the management of pulmonary hypertension.
Autorzy:
Hadi, Dalia D. (AUTHOR)
Marsool, Mohammed Dheyaa Marsool (AUTHOR)
Marsool, Ali Dheyaa Marsool (AUTHOR)
Vora, Neel (AUTHOR)
Al‐Badri, Sajjad G. (AUTHOR)
Al‐Fatlawi, Nabeel H. K. (AUTHOR)
Abbas Al Wssawi, Ameer F. (AUTHOR)
Al‐Ibraheem, Abdullah M. T. (AUTHOR)
Hamza, Khadija A. (AUTHOR)
Prajjwal, Priyadarshi (AUTHOR)
Mateen, Mohammed A. (AUTHOR)
Amir, Omniat (AUTHOR)
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Źródło:
Immunity, Inflammation & Disease. Nov2023, Vol. 11 Issue 11, p1-16. 16p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Disuse-induced muscle fibrosis, cellular senescence, and senescence-associated secretory phenotype in older adults are alleviated during re-ambulation with metformin pre-treatment.
Autorzy:
Petrocelli JJ; Department of Physical Therapy and Athletic Training, University of Utah, Salt Lake City, Utah, USA.
McKenzie AI; Department of Physical Therapy and Athletic Training, University of Utah, Salt Lake City, Utah, USA.
de Hart NMMP; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah, USA.
Reidy PT; Department of Kinesiology, Nutrition, and Health, Miami University, Oxford, Ohio, USA.
Mahmassani ZS; Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA.
Keeble AR; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, USA.
Kaput KL; Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Wahl MP; Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Rondina MT; Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA.; Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Marcus RL; Department of Physical Therapy and Athletic Training, University of Utah, Salt Lake City, Utah, USA.
Welt CK; Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Holland WL; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah, USA.
Funai K; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah, USA.; Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA.
Fry CS; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, USA.
Drummond MJ; Department of Physical Therapy and Athletic Training, University of Utah, Salt Lake City, Utah, USA.; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah, USA.; Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA.
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Źródło:
Aging cell [Aging Cell] 2023 Nov; Vol. 22 (11), pp. e13936. Date of Electronic Publication: 2023 Jul 24.
Typ publikacji:
Randomized Controlled Trial; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Metformin*/pharmacology
Metformin*/therapeutic use
Male ; Female ; Humans ; Senescence-Associated Secretory Phenotype ; Cellular Senescence/genetics ; Muscle, Skeletal ; Inflammation ; Walking ; Collagen ; Fibrosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid.
Autorzy:
Wu, Kang (AUTHOR)
Liu, Yi (AUTHOR)
Xia, Jie (AUTHOR)
Liu, Jiale (AUTHOR)
Wang, Kai (AUTHOR)
Liang, Huijun (AUTHOR)
Xu, Fengli (AUTHOR)
Liu, Dina (AUTHOR)
Nie, Dan (AUTHOR)
Tang, Xin (AUTHOR)
Huang, Ailong (AUTHOR)
Chen, Chang (AUTHOR)
Tang, Ni (AUTHOR)
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Źródło:
Advanced Science. 1/15/2024, Vol. 11 Issue 2, p1-17. 17p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High immunocompetence in chronic hepatitis patients with normal alanine transaminase levels and and negative hepatitis B e‐antigen for the progression of liver fibrosis.
Autorzy:
Cheng, Bianqiao (AUTHOR)
Wu, Dandan (AUTHOR)
Zhang, Ming (AUTHOR)
Chen, Shiming (AUTHOR)
Wu, Xunyuan (AUTHOR)
Zhong, Jingjing (AUTHOR)
Wu, Meimei (AUTHOR)
Huo, Miaomiao (AUTHOR)
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Źródło:
Immunity, Inflammation & Disease. Jan2024, Vol. 12 Issue 1, p1-9. 9p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 22875

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