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Tytuł:
The Sphingolipid-Modulating Drug Opaganib Protects against Radiation-Induced Lung Inflammation and Fibrosis: Potential Uses as a Medical Countermeasure and in Cancer Radiotherapy.
Autorzy:
Maines LW; Apogee Biotechnology Corporation, 1214 Research Blvd, Suite 2015, Hummelstown, PA 17036, USA.
Keller SN; Apogee Biotechnology Corporation, 1214 Research Blvd, Suite 2015, Hummelstown, PA 17036, USA.
Smith RA; Apogee Biotechnology Corporation, 1214 Research Blvd, Suite 2015, Hummelstown, PA 17036, USA.
Green CL; Apogee Biotechnology Corporation, 1214 Research Blvd, Suite 2015, Hummelstown, PA 17036, USA.
Smith CD; Apogee Biotechnology Corporation, 1214 Research Blvd, Suite 2015, Hummelstown, PA 17036, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 15; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
Pulmonary Fibrosis*/drug therapy
Pulmonary Fibrosis*/etiology
Pulmonary Fibrosis*/pathology
Medical Countermeasures*
Pneumonia*
Neoplasms*
Pyridines*
Adamantane/*analogs & derivatives
Mice ; Animals ; Humans ; Sphingolipids/metabolism ; Fibrosis ; Inflammation/drug therapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The role of macrophage polarization and cellular crosstalk in the pulmonary fibrotic microenvironment: a review.
Autorzy:
Zhou BW; The First School of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250014, China.
Liu HM; Department of General Medicine, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250014, China.
Xu F; Department of Pneumology and Critical Care Medicine, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250014, China.
Jia XH; Department of Pneumology and Critical Care Medicine, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250014, China. jiaxinhua_.
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Mar 09; Vol. 22 (1), pp. 172. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Pulmonary Fibrosis*/metabolism
Pulmonary Fibrosis*/pathology
Humans ; Fibrosis ; Macrophages/metabolism ; Cytokines/metabolism ; Signal Transduction ; Fibroblasts/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
NXC736 Attenuates Radiation-Induced Lung Fibrosis via Regulating NLRP3/IL-1β Signaling Pathway.
Autorzy:
Kim SY; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Park S; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Cui R; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Lee H; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Choi H; Nextgen Bioscience, Bundang-gu, Seongnam-si 13487, Gyeonggi-do, Republic of Korea.
Farh ME; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Jo HI; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Lee JH; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Song HJ; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Lee YJ; Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.
Lee YS; Graduate School of Pharmaceutical Sciences and College of Pharmacy, Ewha Womans University, Seoul 03760, Republic of Korea.
Lee BY; Nextgen Bioscience, Bundang-gu, Seongnam-si 13487, Gyeonggi-do, Republic of Korea.
Cho J; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 13; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:
Journal Article
MeSH Terms:
Pulmonary Fibrosis*/drug therapy
Pulmonary Fibrosis*/etiology
Pulmonary Fibrosis*/metabolism
Radiation Injuries*/metabolism
Mice ; Animals ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Lung/pathology ; Fibrosis ; Inflammasomes/metabolism ; Signal Transduction ; Radiation Fibrosis Syndrome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bronchial Asthma, Airway Remodeling and Lung Fibrosis as Successive Steps of One Process.
Autorzy:
Savin IA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev Ave 8, 630090 Novosibirsk, Russia.
Zenkova MA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev Ave 8, 630090 Novosibirsk, Russia.
Sen'kova AV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev Ave 8, 630090 Novosibirsk, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 07; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Pulmonary Fibrosis*/etiology
Pulmonary Fibrosis*/pathology
Asthma*/pathology
Humans ; Animals ; Mice ; Airway Remodeling ; Lung/pathology ; Fibrosis ; Inflammation/pathology ; Biomarkers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An agent-based modeling approach for lung fibrosis in response to COVID-19.
Autorzy:
Islam MA; Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, New York, United States of America.
Getz M; Department of Intelligent Systems Engineering, Indiana University, Bloomington, Indiana, United States of America.
Macklin P; Department of Intelligent Systems Engineering, Indiana University, Bloomington, Indiana, United States of America.
Ford Versypt AN; Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, New York, United States of America.; Department of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, New York, United States of America.; Institute for Artificial Intelligence and Data Science, University at Buffalo, The State University of New York, Buffalo, New York, United States of America.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2023 Dec 21; Vol. 19 (12), pp. e1011741. Date of Electronic Publication: 2023 Dec 21 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Pulmonary Fibrosis*/drug therapy
Pulmonary Fibrosis*/metabolism
Pulmonary Fibrosis*/pathology
COVID-19*/metabolism
Animals ; Mice ; Humans ; Pandemics ; SARS-CoV-2/metabolism ; Lung/metabolism ; Transforming Growth Factor beta/metabolism ; Fibrosis ; Collagen/metabolism ; Fibroblasts/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CD36/Lyn kinase interactions within macrophages promotes pulmonary fibrosis in response to oxidized phospholipid.
Autorzy:
Kwak D; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, 109 Zina Pitcher Place, BSRB 4061, Ann Arbor, MI, 48109, USA.
Bradley PB; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, 109 Zina Pitcher Place, BSRB 4061, Ann Arbor, MI, 48109, USA.
Subbotina N; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, 109 Zina Pitcher Place, BSRB 4061, Ann Arbor, MI, 48109, USA.
Ling S; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, 109 Zina Pitcher Place, BSRB 4061, Ann Arbor, MI, 48109, USA.
Teitz-Tennenbaum S; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, 109 Zina Pitcher Place, BSRB 4061, Ann Arbor, MI, 48109, USA.; Pulmonary Section, Department of Medicine, VA Ann Arbor Health System, Ann Arbor, MI, 48105, USA.
Osterholzer JJ; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, 109 Zina Pitcher Place, BSRB 4061, Ann Arbor, MI, 48109, USA.; Pulmonary Section, Department of Medicine, VA Ann Arbor Health System, Ann Arbor, MI, 48105, USA.
Sisson TH; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, 109 Zina Pitcher Place, BSRB 4061, Ann Arbor, MI, 48109, USA.
Kim KK; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, 109 Zina Pitcher Place, BSRB 4061, Ann Arbor, MI, 48109, USA. .
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Źródło:
Respiratory research [Respir Res] 2023 Dec 14; Vol. 24 (1), pp. 314. Date of Electronic Publication: 2023 Dec 14.
Typ publikacji:
Journal Article
MeSH Terms:
Pulmonary Fibrosis*/metabolism
Mice ; Humans ; Animals ; Phospholipids/metabolism ; Cicatrix/metabolism ; Macrophages/metabolism ; Mice, Knockout ; Fibrosis ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
METTL3-mediated m6A RNA methylation induces the differentiation of lung resident mesenchymal stem cells into myofibroblasts via the miR-21/PTEN pathway.
Autorzy:
Lu Y; Department of Respiratory and Clinical Care Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Liu Z; Department of Respiratory and Clinical Care Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Zhang Y; Department of Respiratory and Clinical Care Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Wu X; Department of Respiratory and Clinical Care Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Bian W; Department of Respiratory and Clinical Care Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Shan S; Department of Respiratory and Clinical Care Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China. shanshan_.
Yang D; Department of Respiratory and Clinical Care Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China. .
Ren T; Department of Respiratory and Clinical Care Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China. .
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Źródło:
Respiratory research [Respir Res] 2023 Nov 28; Vol. 24 (1), pp. 300. Date of Electronic Publication: 2023 Nov 28.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Mesenchymal Stem Cells*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Pulmonary Fibrosis*/metabolism
Animals ; Mice ; Cell Differentiation ; Fibrosis ; Lung/metabolism ; Methylation ; Myofibroblasts/metabolism ; Transforming Growth Factor beta1/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Superiority of systemic bleomycin to intradermal HOCl for the study of interstitial lung disease.
Autorzy:
Morozan A; Meakins Christie Laboratories, McGill University Health Centre and McGill University, Montreal, QC, H4A 3J1, Canada.; The Research Institute of the McGill University Health Centre, McGill University, 1001 Decarie Blvd, Office # EM2-3238, Montreal, QC, H4A 3J1, Canada.
Joy S; Meakins Christie Laboratories, McGill University Health Centre and McGill University, Montreal, QC, H4A 3J1, Canada.; The Research Institute of the McGill University Health Centre, McGill University, 1001 Decarie Blvd, Office # EM2-3238, Montreal, QC, H4A 3J1, Canada.
Fujii U; Meakins Christie Laboratories, McGill University Health Centre and McGill University, Montreal, QC, H4A 3J1, Canada.
Fraser R; Division of Pathology, McGill University Health Centre, Montreal, QC, Canada.
Watters K; Division of Pathology, McGill University Health Centre, Montreal, QC, Canada.
Martin JG; Meakins Christie Laboratories, McGill University Health Centre and McGill University, Montreal, QC, H4A 3J1, Canada.; The Research Institute of the McGill University Health Centre, McGill University, 1001 Decarie Blvd, Office # EM2-3238, Montreal, QC, H4A 3J1, Canada.
Colmegna I; The Research Institute of the McGill University Health Centre, McGill University, 1001 Decarie Blvd, Office # EM2-3238, Montreal, QC, H4A 3J1, Canada. .; Division of Rheumatology, McGill University Health Centre, McGill University, Montreal, QC, Canada. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 23; Vol. 13 (1), pp. 20577. Date of Electronic Publication: 2023 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
Pulmonary Fibrosis*/metabolism
Lung Diseases, Interstitial*/pathology
Scleroderma, Systemic*/pathology
Animals ; Mice ; Hypochlorous Acid/metabolism ; Bleomycin/adverse effects ; Bleomycin/metabolism ; NF-E2-Related Factor 2/metabolism ; Skin/metabolism ; Fibrosis ; Lung/pathology ; Disease Models, Animal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Longitudinal x-ray based lung function measurement for monitoring Nintedanib treatment response in a mouse model of lung fibrosis.
Autorzy:
Khan A; Translational Molecular Imaging, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
Markus MA; Translational Molecular Imaging, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
Svetlove A; Translational Molecular Imaging, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), Göttingen, Germany.
Hülsmann S; Department of Anesthesiology, University Medical Center, Göttingen, Germany.
Alves F; Translational Molecular Imaging, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), Göttingen, Germany.; Clinic of Hematology and Medical Oncology, University Medical Center, Göttingen, Germany.; Institute for Diagnostic and Interventional Radiology, University Medical Center, Göttingen, Germany.
Dullin C; Translational Molecular Imaging, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany. .; Institute for Diagnostic and Interventional Radiology, University Medical Center, Göttingen, Germany. .; Institute for Diagnostic and Interventional Radiology, University Hospital, Heidelberg, Germany. .; Translational Lung Research Center, Heidelberg, Germany. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 30; Vol. 13 (1), pp. 18637. Date of Electronic Publication: 2023 Oct 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Pulmonary Fibrosis*/chemically induced
Pulmonary Fibrosis*/diagnostic imaging
Pulmonary Fibrosis*/drug therapy
Idiopathic Pulmonary Fibrosis*/pathology
Mice ; Animals ; X-Rays ; Lung/pathology ; Fibrosis ; Disease Models, Animal ; Bleomycin/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
NLRP3 Inflammasome Activates Endothelial-to-Mesenchymal Transition via Focal Adhesion Kinase Pathway in Bleomycin-Induced Pulmonary Fibrosis.
Autorzy:
Chen WC; Institute of Emergency and Critical Care Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Department of Chest Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Yu WK; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Department of Chest Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.; Institute of Physiology, College of Medicine, National Yang-Ming University, Taipei 112, Taiwan.
Su VY; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Department of Internal Medicine, Taipei City Hospital, Taipei 110, Taiwan.
Hsu HS; Institute of Emergency and Critical Care Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Division of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Yang KY; Institute of Emergency and Critical Care Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Department of Chest Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.; Cancer Progression Research Center, National Yang-Ming University, Taipei 112, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 31; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
Pulmonary Fibrosis*/metabolism
Male ; Humans ; Mice ; Animals ; Inflammasomes/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Bleomycin/adverse effects ; Endothelial Cells/metabolism ; Focal Adhesion Protein-Tyrosine Kinases ; Mice, Inbred C57BL ; Fibrosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Oxidative Stress and Lung Fibrosis: Towards an Adverse Outcome Pathway.
Autorzy:
Makena P; RAI Services Company, P.O. Box 1487, Winston-Salem, NC 27102, USA.
Kikalova T; Clarivate Analytics, 1500 Spring Garden, Philadelphia, PA 19130, USA.
Prasad GL; Former Employee of RAI Services Company, Winston-Salem, NC 27101, USA.; Prasad Scientific Consulting LLC, 490 Friendship Place Ct, Lewisville, NC 27023, USA.
Baxter SA; RAI Services Company, P.O. Box 1487, Winston-Salem, NC 27102, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 06; Vol. 24 (15). Date of Electronic Publication: 2023 Aug 06.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Pulmonary Fibrosis*/metabolism
Adverse Outcome Pathways*
Lung Injury*/pathology
Humans ; Lung/pathology ; Oxidative Stress ; Fibrosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Loss of ZNF451 mediates fibroblast activation and promotes lung fibrosis.
Autorzy:
Peng H; Department of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Zhang Y; National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, Changsha, Hunan, 410011, China.; Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Min J; National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, Changsha, Hunan, 410011, China.; Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Tan Y; Department of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Liu S; National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, Changsha, Hunan, 410011, China. .; Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China. .
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Źródło:
Respiratory research [Respir Res] 2024 Apr 10; Vol. 25 (1), pp. 160. Date of Electronic Publication: 2024 Apr 10.
Typ publikacji:
Journal Article
MeSH Terms:
Pulmonary Fibrosis*/chemically induced
Pulmonary Fibrosis*/genetics
Pulmonary Fibrosis*/metabolism
Mice ; Animals ; Phosphatidylinositol 3-Kinases/metabolism ; Signal Transduction ; Fibroblasts/metabolism ; Mice, Knockout ; Bleomycin/toxicity ; Lung/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The novel molecular mechanism of pulmonary fibrosis: insight into lipid metabolism from reanalysis of single-cell RNA-seq databases.
Autorzy:
Shi X; Department of Dermatology, Huashan Hospital, and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.
Chen Y; Human Phenome Institute, and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, China Fudan University, Shanghai, China.
Shi M; Department of Thoracic Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Gao F; Wuxi Lung Transplant Center, Wuxi People's Hospital affiliated to Nanjing Medical University, Wuxi, China.
Huang L; Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism & Integrative Biology, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, 200438, China.
Wang W; Wuxi Lung Transplant Center, Wuxi People's Hospital affiliated to Nanjing Medical University, Wuxi, China.; MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.
Wei D; Wuxi Lung Transplant Center, Wuxi People's Hospital affiliated to Nanjing Medical University, Wuxi, China.
Shi C; MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.
Yu Y; Human Phenome Institute, and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, China Fudan University, Shanghai, China.
Xia X; Human Phenome Institute, and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, China Fudan University, Shanghai, China.
Song N; Department of Nephrology, Zhongshan Hospital, Fudan University, Fudan Zhangjiang Institute, Shanghai, People's Republic of China.
Chen X; Department of Thoracic Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Distler JHW; Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen, Nuremberg, Germany.
Lu C; MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China. .
Chen J; Wuxi Lung Transplant Center, Wuxi People's Hospital affiliated to Nanjing Medical University, Wuxi, China. .; Center for Lung Transplantation, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. .
Wang J; Department of Dermatology, Huashan Hospital, and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China. .; Human Phenome Institute, and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, China Fudan University, Shanghai, China. .; Research Unit of Dissecting the Population Genetics and Developing New Technologies for Treatment and Prevention of Skin Phenotypes and Dermatological Diseases (2019RU058), Chinese Academy of Medical Sciences, Beijing, China. .; Institute of Rheumatology, Immunology and Allergy, Fudan University, Shanghai, China. .
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Źródło:
Lipids in health and disease [Lipids Health Dis] 2024 Apr 03; Vol. 23 (1), pp. 98. Date of Electronic Publication: 2024 Apr 03.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Pulmonary Fibrosis*/genetics
Pulmonary Fibrosis*/metabolism
Pulmonary Fibrosis*/pathology
Humans ; Single-Cell Gene Expression Analysis ; Lipid Metabolism/genetics ; Endothelial Cells/metabolism ; Phospholipids/metabolism ; Cholesterol/metabolism ; Phosphatidylcholines
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HSP70 Is a Critical Regulator of HSP90 Inhibitor's Effectiveness in Preventing HCl-Induced Chronic Lung Injury and Pulmonary Fibrosis.
Autorzy:
Colunga Biancatelli RML; Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23509, USA.; Division of Pulmonary and Critical Care, Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
Solopov PA; Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23509, USA.
Day T; Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23509, USA.
Gregory B; Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23509, USA.
Osei-Nkansah M; Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23509, USA.; School of Medicine, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
Dimitropoulou C; Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23509, USA.
Catravas JD; Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23509, USA.; Division of Pulmonary and Critical Care, Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA 23507, USA.; School of Medical Diagnostic & Translational Sciences, College of Health Sciences, Old Dominion University, Norfolk, VA 23509, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 05; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 05.
Typ publikacji:
Journal Article
MeSH Terms:
Pulmonary Fibrosis*/chemically induced
Pulmonary Fibrosis*/drug therapy
Pulmonary Fibrosis*/metabolism
Lung Injury*/chemically induced
Lung Injury*/drug therapy
Antineoplastic Agents*/adverse effects
Benzamides*
Pyrazoles*
Mice ; Humans ; Animals ; Hydrochloric Acid/toxicity ; HSP70 Heat-Shock Proteins/metabolism ; Endothelial Cells/metabolism ; Gefitinib/adverse effects ; HSP90 Heat-Shock Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Chlorogenic Acid Inhibits Progressive Pulmonary Fibrosis in a Diabetic Rat Model.
Autorzy:
Kencana SMS; Department of Anatomy, School of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.; Master Program in Biomedical Sciences, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Arfian N; Department of Anatomy, School of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Yuniartha R; Department of Anatomy, School of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Saputri RLAAW; Department of Anatomy, School of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.; Master Program in Biomedical Sciences, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Munawaroh F; Master Program in Biomedical Sciences, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.; Faculty of Medicine, IPB University, Bogor, West Java, Indonesia.
Sari DCR; Department of Anatomy, School of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
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Źródło:
Iranian journal of medical sciences [Iran J Med Sci] 2024 Feb 01; Vol. 49 (2), pp. 110-120. Date of Electronic Publication: 2024 Feb 01 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Pulmonary Fibrosis*/drug therapy
Pulmonary Fibrosis*/etiology
Pulmonary Fibrosis*/metabolism
Diabetes Mellitus*
Rats ; Animals ; Transforming Growth Factor beta1/genetics ; Transforming Growth Factor beta1/metabolism ; Chlorogenic Acid/pharmacology ; Chlorogenic Acid/therapeutic use ; Rats, Wistar ; Collagen
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Evolutionary genetics of pulmonary anatomical adaptations in deep-diving cetaceans.
Autorzy:
Guo B; Jiangsu Key Laboratory for Bioaffiliationersity and Biotechnology, College of Life Sciences, Nanjing Normal University, 210023, Nanjing, China.
Sun Y; Jiangsu Key Laboratory for Bioaffiliationersity and Biotechnology, College of Life Sciences, Nanjing Normal University, 210023, Nanjing, China.
Wang Y; Jiangsu Key Laboratory for Bioaffiliationersity and Biotechnology, College of Life Sciences, Nanjing Normal University, 210023, Nanjing, China.
Zhang Y; Jiangsu Key Laboratory for Bioaffiliationersity and Biotechnology, College of Life Sciences, Nanjing Normal University, 210023, Nanjing, China.
Zheng Y; Jiangsu Key Laboratory for Bioaffiliationersity and Biotechnology, College of Life Sciences, Nanjing Normal University, 210023, Nanjing, China.
Xu S; Jiangsu Key Laboratory for Bioaffiliationersity and Biotechnology, College of Life Sciences, Nanjing Normal University, 210023, Nanjing, China.
Yang G; Jiangsu Key Laboratory for Bioaffiliationersity and Biotechnology, College of Life Sciences, Nanjing Normal University, 210023, Nanjing, China.
Ren W; Jiangsu Key Laboratory for Bioaffiliationersity and Biotechnology, College of Life Sciences, Nanjing Normal University, 210023, Nanjing, China. .
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Źródło:
BMC genomics [BMC Genomics] 2024 Apr 04; Vol. 25 (1), pp. 339. Date of Electronic Publication: 2024 Apr 04.
Typ publikacji:
Journal Article
MeSH Terms:
Pulmonary Fibrosis*
Animals ; Humans ; Cetacea/genetics ; Cetacea/metabolism ; Lung/metabolism ; Mammals/metabolism ; Oxygen/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel inhalation therapy in pulmonary fibrosis: principles, applications and prospects.
Autorzy:
Zheng M; Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100010, China.; Peking University People's Hospital, Beijing, 100032, China.
Zhu W; Department of Ophthalmology, Changshu No. 2 People's Hospital, Changshu, 215500, China.
Gao F; State Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy School, Chengdu University of Traditional Chinese Medicine, Chengdu, 611130, China.
Zhuo Y; Department of Medical Oncology Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 100010, China.
Zheng M; Department of Medical Oncology Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 100010, China.
Wu G; School of Medical Technology, Beijing Institute of Technology, Beijing, 100081, China. .
Feng C; Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100010, China. .; Peking University People's Hospital, Beijing, 100032, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2024 Mar 29; Vol. 22 (1), pp. 136. Date of Electronic Publication: 2024 Mar 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Pulmonary Fibrosis*/drug therapy
Pulmonary Disease, Chronic Obstructive*/drug therapy
Asthma*/drug therapy
Humans ; Administration, Inhalation ; Respiratory Therapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Exosomes from senescent epithelial cells activate pulmonary fibroblasts via the miR-217-5p/Sirt1 axis in paraquat-induced pulmonary fibrosis.
Autorzy:
Zhang M; Department of Emergency Medicine, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, 241001, Anhui, People's Republic of China.
Xue X; Department of Emergency Medicine, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, 241001, Anhui, People's Republic of China.
Lou Z; Department of Emergency Medicine, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, 241001, Anhui, People's Republic of China.
Lin Y; Department of Emergency Medicine, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, 241001, Anhui, People's Republic of China.
Li Q; Department of Emergency Medicine, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, 241001, Anhui, People's Republic of China.
Huang C; Department of Emergency Medicine, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, 241001, Anhui, People's Republic of China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Mar 26; Vol. 22 (1), pp. 310. Date of Electronic Publication: 2024 Mar 26.
Typ publikacji:
Journal Article
MeSH Terms:
Pulmonary Fibrosis*/genetics
Exosomes*/metabolism
MicroRNAs*/genetics
Humans ; Mice ; Animals ; Paraquat/metabolism ; Paraquat/pharmacology ; beta Catenin/metabolism ; Sirtuin 1/metabolism ; Lung/pathology ; Epithelial Cells/pathology ; Fibroblasts/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Role of Sensory Nerves in Pulmonary Fibrosis.
Autorzy:
Norton CE; Department of Medical Pharmacology and Physiology, University of Missouri, Columbia, MO 65212, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 21; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Pulmonary Fibrosis*/metabolism
Hypertension, Pulmonary*/metabolism
Humans ; Lung/metabolism ; Afferent Pathways ; Respiratory Mucosa/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Early Pulmonary Fibrosis-like Changes in the Setting of Heat Exposure: DNA Damage and Cell Senescence.
Autorzy:
Hou T; School of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang International Science and Technology Cooperation Base of Air Pollution and Health, Hangzhou 310053, China.
Zhang J; School of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang International Science and Technology Cooperation Base of Air Pollution and Health, Hangzhou 310053, China.
Wang Y; School of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang International Science and Technology Cooperation Base of Air Pollution and Health, Hangzhou 310053, China.
Zhang G; School of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang International Science and Technology Cooperation Base of Air Pollution and Health, Hangzhou 310053, China.
Li S; School of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang International Science and Technology Cooperation Base of Air Pollution and Health, Hangzhou 310053, China.
Fan W; School of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang International Science and Technology Cooperation Base of Air Pollution and Health, Hangzhou 310053, China.
Li R; School of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang International Science and Technology Cooperation Base of Air Pollution and Health, Hangzhou 310053, China.
Sun Q; School of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang International Science and Technology Cooperation Base of Air Pollution and Health, Hangzhou 310053, China.
Liu C; School of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang International Science and Technology Cooperation Base of Air Pollution and Health, Hangzhou 310053, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 05; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 05.
Typ publikacji:
Journal Article
MeSH Terms:
Pulmonary Fibrosis*/metabolism
Male ; Mice ; Animals ; Hot Temperature ; Mice, Inbred C57BL ; Lung/pathology ; Transforming Growth Factor beta1/metabolism ; Epithelial-Mesenchymal Transition/physiology ; Cellular Senescence ; Nucleotidyltransferases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 23174

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