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Tytuł :
A Novel NFIX-STAT6 Gene Fusion in Solitary Fibrous Tumor: A Case Report.
Autorzy :
Moura DS; Institute of Biomedicine of Seville (IBiS, CSIC, HUVR, US), 41013 Seville, Spain.
Díaz-Martín J; Institute of Biomedicine of Seville (IBiS, CSIC, HUVR, US), 41013 Seville, Spain.; Pathology Department, Hospital Virgen del Rocío, 41013 Sevilla, Spain.; Centro de Investigación Biomédica en Red del Cáncer (CIBERONC), 28029 Madrid, Spain.
Bagué S; Pathology Department-CIBERONC, Sant Pau Hospital, 08041 Barcelona, Spain.
Orellana-Fernandez R; Pathology Department-CIBERONC, Sant Pau Hospital, 08041 Barcelona, Spain.
Sebio A; Medical Oncology Department, Sant Pau Hospital, 08041 Barcelona, Spain.
Mondaza-Hernandez JL; Fundacion Jimenez Diaz University Hospital Health Research Institute (IIS/FJD), 28015 Madrid, Spain.
Salguero-Aranda C; Institute of Biomedicine of Seville (IBiS, CSIC, HUVR, US), 41013 Seville, Spain.; Pathology Department, Hospital Virgen del Rocío, 41013 Sevilla, Spain.; Centro de Investigación Biomédica en Red del Cáncer (CIBERONC), 28029 Madrid, Spain.
Rojo F; Pathology Department, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain.
Hindi N; Fundacion Jimenez Diaz University Hospital Health Research Institute (IIS/FJD), 28015 Madrid, Spain.; Medical Oncology Department, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain.; General de Villalba University Hospital, 28400 Madrid, Spain.
Fletcher CDM; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02215, USA.; Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.
Martin-Broto J; Fundacion Jimenez Diaz University Hospital Health Research Institute (IIS/FJD), 28015 Madrid, Spain.; Medical Oncology Department, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain.; General de Villalba University Hospital, 28400 Madrid, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 13; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 13.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Gene Fusion*
NFI Transcription Factors/*genetics
Oncogene Proteins, Fusion/*genetics
STAT6 Transcription Factor/*genetics
Solitary Fibrous Tumors/*genetics
Solitary Fibrous Tumors/*pathology
Aged ; Female ; Humans ; Prognosis
Czasopismo naukowe
Tytuł :
Targeting the membrane fusion event of human respiratory syncytial virus with rationally designed α-helical hairpin traps.
Autorzy :
Liu Q; Department of Respiratory, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Zhou J; Department of Neurosurgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Gao J; Department of Respiratory, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China. Electronic address: .
Zhang X; School of Laboratory Medicine, Xinxiang Medical University, Xinxiang 453003, China. Electronic address: .
Yang J; School of Laboratory Medicine, Xinxiang Medical University, Xinxiang 453003, China.
Hu C; Department of Respiratory, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Chu W; Department of Respiratory, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Yao M; Department of Respiratory, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
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Źródło :
Life sciences [Life Sci] 2021 Sep 01; Vol. 280, pp. 119695. Date of Electronic Publication: 2021 Jun 07.
Typ publikacji :
Journal Article
MeSH Terms :
Respiratory Syncytial Virus Infections/*metabolism
Respiratory Syncytial Virus, Human/*physiology
Viral Fusion Proteins/*metabolism
Humans ; Membrane Fusion ; Models, Molecular ; Protein Conformation, alpha-Helical ; Protein Multimerization ; Respiratory Syncytial Virus, Human/chemistry ; Viral Fusion Proteins/chemistry
Czasopismo naukowe
Tytuł :
Myomerger promotes fusion pore by elastic coupling between proximal membrane leaflets and hemifusion diaphragm.
Autorzy :
Golani G; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.
Leikina E; Section on Membrane Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA.
Melikov K; Section on Membrane Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA.
Whitlock JM; Section on Membrane Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA.
Gamage DG; Division of Molecular Cardiovascular Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.
Luoma-Overstreet G; Section on Membrane Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA.
Millay DP; Division of Molecular Cardiovascular Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, 45229, USA.
Kozlov MM; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel. .
Chernomordik LV; Section on Membrane Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Jan 21; Vol. 12 (1), pp. 495. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Membrane Fusion*
Cell Membrane/*metabolism
Membrane Proteins/*metabolism
Myoblasts/*metabolism
Algorithms ; Animals ; Cell Fusion ; Cell Line ; Lipid Bilayers/metabolism ; Membrane Lipids/metabolism ; Membrane Proteins/genetics ; Mice ; Mice, Knockout ; Models, Theoretical ; Myoblasts/cytology ; NIH 3T3 Cells
Czasopismo naukowe
Tytuł :
Transient Excursions to Membrane Core as Determinants of Influenza Virus Fusion Peptide Activity.
Autorzy :
Worch R; Institute of Physics, Polish Academy of Sciences, Aleja Lotnikow 32/46, 02-668 Warsaw, Poland.
Dudek A; Centre of New Technologies, University of Warsaw, Banacha 2c, 02-097 Warsaw, Poland.
Borkowska P; Institute of Physics, Polish Academy of Sciences, Aleja Lotnikow 32/46, 02-668 Warsaw, Poland.
Setny P; Centre of New Technologies, University of Warsaw, Banacha 2c, 02-097 Warsaw, Poland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 18; Vol. 22 (10). Date of Electronic Publication: 2021 May 18.
Typ publikacji :
Journal Article
MeSH Terms :
Orthomyxoviridae/*metabolism
Viral Fusion Proteins/*metabolism
Cell Membrane/metabolism ; Hemagglutinin Glycoproteins, Influenza Virus/chemistry ; Influenza A virus/metabolism ; Influenza A virus/pathogenicity ; Lipid Bilayers/chemistry ; Liposomes/metabolism ; Membrane Fusion ; Membranes/metabolism ; Models, Theoretical ; Molecular Dynamics Simulation ; Orthomyxoviridae/pathogenicity ; Viral Fusion Proteins/chemistry
Czasopismo naukowe
Tytuł :
Novel Roles of the N1 Loop and N4 Alpha-Helical Region of the Nipah Virus Fusion Glycoprotein in Modulating Early and Late Steps of the Membrane Fusion Cascade.
Autorzy :
Zamora JLR; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Ortega V; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Johnston GP; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Li J; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Aguilar HC; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA .
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Źródło :
Journal of virology [J Virol] 2021 Apr 12; Vol. 95 (9). Date of Electronic Publication: 2021 Apr 12 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Membrane Fusion*
Virus Internalization*
Henipavirus Infections/*virology
Nipah Virus/*physiology
Viral Fusion Proteins/*chemistry
Animals ; Chlorocebus aethiops ; HEK293 Cells ; Humans ; Protein Conformation ; Protein Conformation, alpha-Helical ; Vero Cells
Czasopismo naukowe
Tytuł :
annoFuse: an R Package to annotate, prioritize, and interactively explore putative oncogenic RNA fusions.
Autorzy :
Gaonkar KS; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Marini F; Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.; Center for Thrombosis and Hemostasis, Mainz, Germany.
Rathi KS; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Jain P; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Zhu Y; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Chimicles NA; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Brown MA; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Naqvi AS; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Zhang B; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Storm PB; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Maris JM; Division of Oncology, Children's Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Raman P; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Resnick AC; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Strauch K; Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Taroni JN; Alex's Lemonade Stand Foundation Childhood Cancer Data Lab, Philadelphia, PA, USA.
Rokita JL; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA. .; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA. .; Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA. .
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2020 Dec 14; Vol. 21 (1), pp. 577. Date of Electronic Publication: 2020 Dec 14.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Fusion*
Software*
Neoplasms/*genetics
RNA/*metabolism
Algorithms ; Humans ; Neoplasms/pathology ; Oncogene Proteins, Fusion/genetics ; Oncogene Proteins, Fusion/metabolism ; RNA/genetics
Czasopismo naukowe
Tytuł :
Detection of novel and recurrent conjoined genes in non-Hodgkin B-cell lymphoma.
Autorzy :
Matsumoto Y; Department of Hematology, Japanese Red Cross Kyoto Daiichi Hospital, Kyoto, Japan.
Tsukamoto T; Division of Hematology and Oncology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Chinen Y; Division of Hematology and Oncology, Kyoto Prefectural University of Medicine, Kyoto, Japan.; Department of Hematology, Fukuchiyama City Hospital, Fukuchiyama, Japan.
Shimura Y; Division of Hematology and Oncology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Sasaki N; Department of Hematology, Japanese Red Cross Kyoto Daini Hospital, Kyoto, Japan.
Nagoshi H; Department of Hematology and Oncology, Hiroshima University, Hiroshima, Japan.
Sato R; Department of Genomic Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Adachi H; Department of Genomic Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Nakano M; Department of Genomic Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Horiike S; Division of Hematology and Oncology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Kuroda J; Division of Hematology and Oncology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Taki T; Department of Medical Technology, Kyorin University Faculty of Health Science, Tokyo, Japan.
Tashiro K; Department of Genomic Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Taniwaki M; Center for Molecular Diagnostics and Therapeutics, Kyoto Prefectural University of Medicine, Kyoto, Japan.
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Źródło :
Journal of clinical and experimental hematopathology : JCEH [J Clin Exp Hematop] 2021 Jun 05; Vol. 61 (2), pp. 71-77. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Journal Article
MeSH Terms :
Oncogene Fusion*
Lymphoma, B-Cell/*genetics
Oncogene Proteins, Fusion/*genetics
Base Sequence ; Cell Line, Tumor ; Gene Dosage ; Humans ; Sequence Analysis, RNA ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Myxoid mesenchymal intraventricular brain tumour with EWSR1-CREB1 gene fusion in an adult woman.
Autorzy :
Valente Aguiar P; Neurosurgery Department, Centro Hospitalar Universitário São João, Porto, Portugal. .; Faculty of Medicine, University of Porto, Porto, Portugal. .
Pinheiro J; IPATIMUP - Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal.; Department of Pathology, Centro Hospitalar Universitário São João, Porto, Portugal.
Lima J; Faculty of Medicine, University of Porto, Porto, Portugal.; Department of Pathology, Centro Hospitalar Universitário São João, Porto, Portugal.; i3S - Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal.
Vaz R; Neurosurgery Department, Centro Hospitalar Universitário São João, Porto, Portugal.; Faculty of Medicine, University of Porto, Porto, Portugal.; Neurosciences Centre, Hospital CUF, Porto, Portugal.
Linhares P; Neurosurgery Department, Centro Hospitalar Universitário São João, Porto, Portugal.; Faculty of Medicine, University of Porto, Porto, Portugal.; Neurosciences Centre, Hospital CUF, Porto, Portugal.
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 May; Vol. 478 (5), pp. 1019-1024. Date of Electronic Publication: 2020 Jul 06.
Typ publikacji :
Case Reports
MeSH Terms :
Gene Fusion*
Biomarkers, Tumor/*genetics
Cerebral Ventricle Neoplasms/*genetics
Histiocytoma, Malignant Fibrous/*genetics
Oncogene Proteins, Fusion/*genetics
Cerebral Ventricle Neoplasms/diagnostic imaging ; Cerebral Ventricle Neoplasms/pathology ; Cerebral Ventricle Neoplasms/surgery ; Female ; Histiocytoma, Malignant Fibrous/diagnostic imaging ; Histiocytoma, Malignant Fibrous/pathology ; Histiocytoma, Malignant Fibrous/surgery ; Humans ; Middle Aged ; Treatment Outcome
SCR Disease Name :
Histiocytoma, Angiomatoid Fibrous
Raport
Tytuł :
Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML).
Autorzy :
Lu T; Anhui Province Key Laboratory of Medical Physics and Technology; CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China; Key Laboratory of Xin'an Medicine, Ministry of Education, Anhui University of Chinese Medicine, Hefei, Anhui, 230012, PR China.
Cao J; Anhui Province Key Laboratory of Medical Physics and Technology; CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China; University of Science and Technology of China, Hefei, Anhui, 230026, PR China.
Zou F; Anhui Province Key Laboratory of Medical Physics and Technology; CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China.
Li X; Anhui Province Key Laboratory of Medical Physics and Technology; CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China.
Wang A; Anhui Province Key Laboratory of Medical Physics and Technology; CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China.
Wang W; Anhui Province Key Laboratory of Medical Physics and Technology; CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China.
Liang H; Anhui Province Key Laboratory of Medical Physics and Technology; CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China.
Liu Q; Anhui Province Key Laboratory of Medical Physics and Technology; CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China.
Hu C; Anhui Province Key Laboratory of Medical Physics and Technology; CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China.
Chen C; Anhui Province Key Laboratory of Medical Physics and Technology; CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China.
Hu Z; Anhui Province Key Laboratory of Medical Physics and Technology; CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China.
Wang W; Anhui Province Key Laboratory of Medical Physics and Technology; CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China.
Li L; Department of Hematology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, PR China.
Ge J; Department of Hematology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, PR China.
Shen Y; The First Hospital of Jiaxing, 1882 Zhonghuan South Rd, Jiaxing, Zhejiang, 314000, PR China.
Ren T; Anhui Province Key Laboratory of Medical Physics and Technology; CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China.
Liu J; Anhui Province Key Laboratory of Medical Physics and Technology; CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China; University of Science and Technology of China, Hefei, Anhui, 230026, PR China.
Xia R; Department of Hematology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, PR China. Electronic address: .
Liu Q; Anhui Province Key Laboratory of Medical Physics and Technology; CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China; University of Science and Technology of China, Hefei, Anhui, 230026, PR China; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, Anhui, 230031, PR China; Precision Medicine Research Laboratory of Anhui Province, Hefei, Anhui, 230088, PR China; Institute of Physical Science and Information Technology, Anhui University, Hefei, Anhui, 230601, PR China. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Apr 15; Vol. 897, pp. 173944. Date of Electronic Publication: 2021 Feb 11.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Drug Resistance, Neoplasm/*drug effects
Fusion Proteins, bcr-abl/*antagonists & inhibitors
Imatinib Mesylate/*pharmacology
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*drug therapy
Protein Kinase Inhibitors/*pharmacology
Animals ; Apoptosis/drug effects ; Cell Proliferation/drug effects ; Female ; Fusion Proteins, bcr-abl/genetics ; Fusion Proteins, bcr-abl/metabolism ; Gene Fusion ; Humans ; K562 Cells ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/enzymology ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology ; Mice ; Mice, Nude ; Mutation ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Evolutionarily related small viral fusogens hijack distinct but modular actin nucleation pathways to drive cell-cell fusion.
Autorzy :
Chan KMC; University of California Berkeley/University of California San Francisco Graduate Group in Bioengineering, Berkeley, CA 94720.; Department of Bioengineering & Biophysics Group, University of California, Berkeley, CA 94720.; Physiology Course, Marine Biological Laboratory, Woods Hole, MA 02543.
Arthur AL; Physiology Course, Marine Biological Laboratory, Woods Hole, MA 02543.; Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455.
Morstein J; Physiology Course, Marine Biological Laboratory, Woods Hole, MA 02543.; Department of Chemistry, New York University, New York, NY 10003.
Jin M; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.
Bhat A; Physiology Course, Marine Biological Laboratory, Woods Hole, MA 02543.; National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, 560065, India.
Schlesinger D; Physiology Course, Marine Biological Laboratory, Woods Hole, MA 02543.; Science for Life Laboratory, Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Division of Genome Biology, Stockholm 17165, Sweden.
Son S; Department of Bioengineering & Biophysics Group, University of California, Berkeley, CA 94720.; Physiology Course, Marine Biological Laboratory, Woods Hole, MA 02543.
Stevens DA; Physiology Course, Marine Biological Laboratory, Woods Hole, MA 02543.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093.
Drubin DG; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.
Fletcher DA; University of California Berkeley/University of California San Francisco Graduate Group in Bioengineering, Berkeley, CA 94720; .; Department of Bioengineering & Biophysics Group, University of California, Berkeley, CA 94720.; Physiology Course, Marine Biological Laboratory, Woods Hole, MA 02543.; Division of Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.; Chan Zuckerberg Biohub, San Francisco, CA 94158.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jan 05; Vol. 118 (1).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Actins/*metabolism
Membrane Fusion/*physiology
Membrane Fusion Proteins/*metabolism
Actin Cytoskeleton/metabolism ; Amino Acid Sequence/genetics ; Animals ; Biological Evolution ; Cell Fusion/methods ; Cell Line ; Cell Membrane/metabolism ; Cytoskeleton/metabolism ; Evolution, Molecular ; Humans ; Orthoreovirus/genetics ; Protein Binding/genetics ; Reoviridae/genetics ; Viral Fusion Proteins/chemistry ; Viral Fusion Proteins/metabolism ; Viral Nonstructural Proteins/metabolism ; Virus Internalization
Czasopismo naukowe
Tytuł :
Application of error-prone PCR to functionally probe the morbillivirus Haemagglutinin protein.
Autorzy :
Gallo G; The Pirbright Institute, Guildford, Surrey, GU24 0NF, UK.
Conceicao C; The Pirbright Institute, Guildford, Surrey, GU24 0NF, UK.
Tsirigoti C; The Pirbright Institute, Guildford, Surrey, GU24 0NF, UK.
Willett B; MRC University of Glasgow Centre for Virus Research, Glasgow, UK.
Graham SC; Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK.
Bailey D; The Pirbright Institute, Guildford, Surrey, GU24 0NF, UK.
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Źródło :
The Journal of general virology [J Gen Virol] 2021 Apr; Vol. 102 (4).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Adhesion Molecules/*metabolism
Hemagglutinins, Viral/*metabolism
Peste-des-petits-ruminants virus/*metabolism
Polymerase Chain Reaction/*methods
Signaling Lymphocytic Activation Molecule Family Member 1/*metabolism
Viral Fusion Proteins/*metabolism
Animals ; Host Microbial Interactions ; Membrane Fusion ; Sheep
Czasopismo naukowe
Tytuł :
Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell-cell fusion.
Autorzy :
Thakur N; The Pirbright Institute, Ash Road, Pirbright, Woking, GU24 0NF, UK.
Conceicao C; The Pirbright Institute, Ash Road, Pirbright, Woking, GU24 0NF, UK.
Isaacs A; University of Queensland, Brisbane, Queensland 4071, Australia.
Human S; The Pirbright Institute, Ash Road, Pirbright, Woking, GU24 0NF, UK.
Modhiran N; University of Queensland, Brisbane, Queensland 4071, Australia.
McLean RK; The Pirbright Institute, Ash Road, Pirbright, Woking, GU24 0NF, UK.
Pedrera M; The Pirbright Institute, Ash Road, Pirbright, Woking, GU24 0NF, UK.
Tan TK; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.
Rijal P; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.
Townsend A; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.
Taylor G; The Pirbright Institute, Ash Road, Pirbright, Woking, GU24 0NF, UK.
Young PR; University of Queensland, Brisbane, Queensland 4071, Australia.
Watterson D; University of Queensland, Brisbane, Queensland 4071, Australia.
Chappell KJ; University of Queensland, Brisbane, Queensland 4071, Australia.
Graham SP; The Pirbright Institute, Ash Road, Pirbright, Woking, GU24 0NF, UK.
Bailey D; The Pirbright Institute, Ash Road, Pirbright, Woking, GU24 0NF, UK.
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Źródło :
The Journal of general virology [J Gen Virol] 2021 Jan; Vol. 102 (1). Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
High-Throughput Screening Assays*
Antibodies, Neutralizing/*pharmacology
Antibodies, Viral/*pharmacology
COVID-19/*diagnosis
Henipavirus Infections/*diagnosis
Respiratory Syncytial Virus Infections/*diagnosis
Viral Fusion Proteins/*antagonists & inhibitors
Animals ; Antibodies, Neutralizing/isolation & purification ; Antibodies, Neutralizing/metabolism ; Antibodies, Viral/isolation & purification ; Antibodies, Viral/metabolism ; COVID-19/immunology ; COVID-19/virology ; Cell Fusion ; Convalescence ; Genes, Reporter ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; HEK293 Cells ; Henipavirus Infections/immunology ; Henipavirus Infections/virology ; Humans ; Immune Sera/chemistry ; Luciferases/genetics ; Luciferases/metabolism ; Models, Molecular ; Nipah Virus/immunology ; Nipah Virus/pathogenicity ; Protein Conformation ; Respiratory Syncytial Virus Infections/immunology ; Respiratory Syncytial Virus Infections/virology ; Respiratory Syncytial Virus, Human/immunology ; Respiratory Syncytial Virus, Human/pathogenicity ; SARS-CoV-2/immunology ; SARS-CoV-2/pathogenicity ; Swine ; Viral Fusion Protein Inhibitors/chemistry ; Viral Fusion Protein Inhibitors/metabolism ; Viral Fusion Protein Inhibitors/pharmacology ; Viral Fusion Proteins/genetics ; Viral Fusion Proteins/immunology
Czasopismo naukowe
Tytuł :
Human transcription factor and protein kinase gene fusions in human cancer.
Autorzy :
Salokas K; Systems Pathology/Biology Research Group, Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland.
Weldatsadik RG; Systems Pathology/Biology Research Group, Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland.
Varjosalo M; Systems Pathology/Biology Research Group, Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland. .
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Źródło :
Scientific reports [Sci Rep] 2020 Aug 25; Vol. 10 (1), pp. 14169. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji :
Journal Article
MeSH Terms :
Oncogene Fusion*/genetics
Neoplasms/*genetics
Oncogene Proteins, Fusion/*genetics
Protein Kinases/*genetics
Transcription Factors/*genetics
Carcinogenesis/genetics ; Chromosomes, Human/genetics ; Chromosomes, Human/ultrastructure ; Datasets as Topic ; Gene Expression Regulation, Neoplastic/genetics ; Genes, Neoplasm ; Humans ; Metabolic Networks and Pathways/genetics ; Oncogene Proteins, Fusion/metabolism ; Open Reading Frames/genetics ; Protein Domains/genetics ; Protein Kinases/metabolism ; Signal Transduction/genetics ; Structure-Activity Relationship ; Transcription Factors/metabolism ; Translocation, Genetic
Czasopismo naukowe
Tytuł :
Roles of Cholesterol in Early and Late Steps of the Nipah Virus Membrane Fusion Cascade.
Autorzy :
Contreras EM; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Johnston GP; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Buchholz DW; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Ortega V; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Monreal IA; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Zamora JLR; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Cheung T; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Aguilar HC; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA .
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Źródło :
Journal of virology [J Virol] 2021 Feb 24; Vol. 95 (6). Date of Electronic Publication: 2021 Feb 24 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cholesterol/*metabolism
Membrane Fusion/*physiology
Nipah Virus/*physiology
Cholesterol/deficiency ; Giant Cells/metabolism ; Membrane Lipids/analysis ; Membrane Lipids/metabolism ; Nipah Virus/metabolism ; Viral Envelope Proteins/genetics ; Viral Envelope Proteins/metabolism ; Viral Fusion Proteins/genetics ; Viral Fusion Proteins/metabolism ; Virion/metabolism ; Virus Internalization
Czasopismo naukowe
Tytuł :
Experimental Evolution To Isolate Vaccinia Virus Adaptive G9 Mutants That Overcome Membrane Fusion Inhibition via the Vaccinia Virus A56/K2 Protein Complex.
Autorzy :
Hong GC; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan, Republic of China.; Genome and Systems Biology Degree Program, Academia Sinica and National Taiwan University, Taipei, Taiwan, Republic of China.
Tsai CH; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan, Republic of China.
Chang W; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan, Republic of China .; Genome and Systems Biology Degree Program, Academia Sinica and National Taiwan University, Taipei, Taiwan, Republic of China.
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Źródło :
Journal of virology [J Virol] 2020 May 04; Vol. 94 (10). Date of Electronic Publication: 2020 May 04 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Membrane Fusion*
Mutation*
Vaccinia virus/*genetics
Vaccinia virus/*isolation & purification
Viral Proteins/*genetics
Cell Fusion ; Cell Membrane ; Evolution, Molecular ; Gene Expression Regulation, Viral ; Genes, Viral/genetics ; Genome, Viral ; HeLa Cells ; Humans ; Recombinant Proteins ; Vaccinia virus/growth & development ; Viral Fusion Proteins/genetics ; Viral Fusion Proteins/isolation & purification ; Viral Proteins/isolation & purification ; Virus Internalization
Czasopismo naukowe
Tytuł :
Fusogenicity of the Ghana Virus ( Henipavirus : Ghanaian bat henipavirus ) Fusion Protein is Controlled by the Cytoplasmic Domain of the Attachment Glycoprotein.
Autorzy :
Voigt K; Institute of Virology, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.; Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.
Hoffmann M; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, 37077 Göttingen, Germany.
Drexler JF; Institute of Virology, Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10117 Berlin, Germany.
Müller MA; Institute of Virology, Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10117 Berlin, Germany.
Drosten C; Institute of Virology, Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10117 Berlin, Germany.
Herrler G; Institute of Virology, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.
Krüger N; Institute of Virology, University of Veterinary Medicine Hannover, 30559 Hannover, Germany. .; Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine Hannover, 30559 Hannover, Germany. .
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Źródło :
Viruses [Viruses] 2019 Aug 29; Vol. 11 (9). Date of Electronic Publication: 2019 Aug 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Fusion*
Henipavirus/*metabolism
Viral Envelope Proteins/*chemistry
Viral Envelope Proteins/*metabolism
Viral Fusion Proteins/*metabolism
Animals ; Cell Line ; Chiroptera ; Chlorocebus aethiops ; HEK293 Cells ; Henipavirus/genetics ; Host Specificity ; Humans ; Protein Domains ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Sequence Deletion ; Vero Cells ; Viral Envelope Proteins/genetics ; Viral Fusion Proteins/genetics
Czasopismo naukowe
Tytuł :
Beneficial tyrosine kinase inhibitor therapy in a patient with relapsed BCR-ABL1-like acute lymphoblastic leukemia with CCDC88C-PDGFRB fusion.
Autorzy :
Oya S; Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.
Morishige S; Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.
Ozawa H; Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.
Sasaki K; Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, 812-8582, Japan.
Semba Y; Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, 812-8582, Japan.
Yamasaki Y; Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.
Nakamura T; Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.
Aoyama K; Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.
Seki R; Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.
Mouri F; Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.
Osaki K; Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.
Miyamoto T; Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, 812-8582, Japan.
Maeda T; Center for Cellular and Molecular Medicine, Kyushu University Hospital, Fukuoka, 812-8582, Japan.
Nagafuji K; Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan. .
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Źródło :
International journal of hematology [Int J Hematol] 2021 Feb; Vol. 113 (2), pp. 285-289. Date of Electronic Publication: 2020 Sep 19.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Intracellular Signaling Peptides and Proteins/*genetics
Microfilament Proteins/*genetics
Oncogene Proteins, Fusion/*genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Protein Kinase Inhibitors/*therapeutic use
Receptor, Platelet-Derived Growth Factor beta/*genetics
Biomarkers ; Combined Modality Therapy ; Female ; Fusion Proteins, bcr-abl/genetics ; Genetic Testing ; Humans ; Molecular Targeted Therapy/adverse effects ; Molecular Targeted Therapy/methods ; Neoplasm, Residual/diagnosis ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/diagnosis ; Protein Kinase Inhibitors/administration & dosage ; Protein Kinase Inhibitors/adverse effects ; Recurrence ; Retreatment ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
A fusion of CD63-BCAR4 identified in lung adenocarcinoma promotes tumorigenicity and metastasis.
Autorzy :
Bae K; College of Veterinary Medicine, Konkuk University, Seoul, 05029, Republic of Korea.
Kim JH; College of Health Science, Cheongju University, Cheongju, 28503, Republic of Korea.
Jung H; College of Veterinary Medicine, Konkuk University, Seoul, 05029, Republic of Korea.
Kong SY; National Cancer Center Graduate School of Cancer Science and Policy, Goyang, 10408, Gyeonggi, Republic of Korea.; Research Institute, National Cancer Center, Goyang, 10408, Gyeonggi, Republic of Korea.; Hospital, National Cancer Center, Goyang, 10408, Gyeonggi, Republic of Korea.
Kim YH; National Cancer Center Graduate School of Cancer Science and Policy, Goyang, 10408, Gyeonggi, Republic of Korea.; Research Institute, National Cancer Center, Goyang, 10408, Gyeonggi, Republic of Korea.
Kim S; Research Institute, National Cancer Center, Goyang, 10408, Gyeonggi, Republic of Korea.
Lee GK; Research Institute, National Cancer Center, Goyang, 10408, Gyeonggi, Republic of Korea.; Hospital, National Cancer Center, Goyang, 10408, Gyeonggi, Republic of Korea.
Lee JS; National Cancer Center Graduate School of Cancer Science and Policy, Goyang, 10408, Gyeonggi, Republic of Korea.
Lee JJ; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA.
Ju YS; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea.
Choi YK; College of Veterinary Medicine, Konkuk University, Seoul, 05029, Republic of Korea.
Yoon KA; College of Veterinary Medicine, Konkuk University, Seoul, 05029, Republic of Korea. .
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Źródło :
British journal of cancer [Br J Cancer] 2021 Jan; Vol. 124 (1), pp. 290-298. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenocarcinoma of Lung/*genetics
Lung Neoplasms/*genetics
Oncogene Fusion/*genetics
RNA, Long Noncoding/*genetics
Tetraspanin 30/*genetics
Adenocarcinoma of Lung/pathology ; Animals ; Carcinogenesis/genetics ; Cell Movement ; Heterografts ; Humans ; Lung Neoplasms/pathology ; Mice ; Oncogene Proteins, Fusion/genetics
Czasopismo naukowe
Tytuł :
Lumbar spine fusion outcomes using a cellular bone allograft with lineage-committed bone-forming cells in 96 patients.
Autorzy :
Elgafy H; Department of Orthopaedic Surgery, University of Toledo Medical Center, 3065 Arlington Avenue, Toledo, OH, 43614, USA. .
Wetzell B; Department of Orthopaedic Surgery, University of Toledo Medical Center, 3065 Arlington Avenue, Toledo, OH, 43614, USA.
Gillette M; Department of Orthopaedic Surgery, University of Toledo Medical Center, 3065 Arlington Avenue, Toledo, OH, 43614, USA.
Semaan H; Department of Orthopaedic Surgery, University of Toledo Medical Center, 3065 Arlington Avenue, Toledo, OH, 43614, USA.
Rowland A; Department of Orthopaedic Surgery, University of Toledo Medical Center, 3065 Arlington Avenue, Toledo, OH, 43614, USA.
Balboa CA; Department of Orthopaedic Surgery, University of Toledo Medical Center, 3065 Arlington Avenue, Toledo, OH, 43614, USA.
Mierzwa TA; Department of Orthopaedic Surgery, University of Toledo Medical Center, 3065 Arlington Avenue, Toledo, OH, 43614, USA.
McLean JB; Department of Orthopaedic Surgery, University of Toledo Medical Center, 3065 Arlington Avenue, Toledo, OH, 43614, USA.
Dorsch K; Department of Orthopaedic Surgery, University of Toledo Medical Center, 3065 Arlington Avenue, Toledo, OH, 43614, USA.
Moore MA; Department of Orthopaedic Surgery, University of Toledo Medical Center, 3065 Arlington Avenue, Toledo, OH, 43614, USA.
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Źródło :
BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2021 Aug 17; Vol. 22 (1), pp. 699. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji :
Journal Article
MeSH Terms :
Lumbar Vertebrae*/diagnostic imaging
Lumbar Vertebrae*/surgery
Spinal Fusion*/adverse effects
Allografts ; Humans ; Minimally Invasive Surgical Procedures ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Engineering of Bio-Adhesive Ligand Containing Recombinant RGD and PHSRN Fibronectin Cell-Binding Domains in Fusion with a Colored Multi Affinity Tag: Simple Approach for Fragment Study from Expression to Adsorption.
Autorzy :
Ben Abla A; EBInnov®, Ecole de Biologie Industrielle, 49 Avenue des Genottes, 95000 Cergy, France.; Unité de Recherche Biomatériaux Innovants et Interfaces URB2i, Université Paris Sorbonne Nord, 74 Rue Marcel Cachin, 93017 Bobigny, France.
Boeuf G; EBInnov®, Ecole de Biologie Industrielle, 49 Avenue des Genottes, 95000 Cergy, France.
Elmarjou A; Plateforme de Production D'Anticorps et de Protéines Recombinantes, Institut Curie/CNRS UMR144, 75248 Paris, France.
Dridi C; EBInnov®, Ecole de Biologie Industrielle, 49 Avenue des Genottes, 95000 Cergy, France.; Unité de Recherche Biomatériaux Innovants et Interfaces URB2i, Université Paris Sorbonne Nord, 74 Rue Marcel Cachin, 93017 Bobigny, France.
Poirier F; Unité de Recherche Biomatériaux Innovants et Interfaces URB2i, Université Paris Sorbonne Nord, 74 Rue Marcel Cachin, 93017 Bobigny, France.
Changotade S; Unité de Recherche Biomatériaux Innovants et Interfaces URB2i, Université Paris Sorbonne Nord, 74 Rue Marcel Cachin, 93017 Bobigny, France.
Lutomski D; Unité de Recherche Biomatériaux Innovants et Interfaces URB2i, Université Paris Sorbonne Nord, 74 Rue Marcel Cachin, 93017 Bobigny, France.
Elm'selmi A; EBInnov®, Ecole de Biologie Industrielle, 49 Avenue des Genottes, 95000 Cergy, France.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 08; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 08.
Typ publikacji :
Journal Article
MeSH Terms :
Affinity Labels*
Biomimetic Materials*
Fibronectins*
Oligopeptides*
Peptide Fragments*
Recombinant Fusion Proteins/*chemistry
Adsorption ; Cell Adhesion ; Coated Materials, Biocompatible ; Escherichia coli ; Extracellular Matrix/chemistry ; Genetic Vectors ; Integrin alpha5beta1/metabolism ; Ligands ; Mass Spectrometry ; Polystyrenes ; Protein Binding ; Protein Domains ; Protein Engineering ; Recombinant Fusion Proteins/isolation & purification ; Recombinant Fusion Proteins/metabolism
Czasopismo naukowe

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