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Wyszukujesz frazę ""gamma-Glutamyltransferase"" wg kryterium: Temat


Tytuł:
The Role of Transglutaminase 2 in Cancer: An Update.
Autorzy:
Zaltron E; Department of Biology, University of Padua, 35131 Padua, Italy.
Vianello F; Department of Biology, University of Padua, 35131 Padua, Italy.
Ruzza A; Department of Biology, University of Padua, 35131 Padua, Italy.
Palazzo A; Department of Biology, University of Padua, 35131 Padua, Italy.
Brillo V; Department of Biology, University of Padua, 35131 Padua, Italy.
Celotti I; Department of Biology, University of Padua, 35131 Padua, Italy.
Scavezzon M; Department of Biology, University of Padua, 35131 Padua, Italy.
Rossin F; Department of Biology, University of Rome 'Tor Vergata', 00133 Rome, Italy.
Leanza L; Department of Biology, University of Padua, 35131 Padua, Italy.
Severin F; Department of Biology, University of Padua, 35131 Padua, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 28; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Protein Glutamine gamma Glutamyltransferase 2*
Neoplasms*
Humans ; GTP-Binding Proteins/metabolism ; Transglutaminases/metabolism ; Signal Transduction ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Mesenchymal Transglutaminase 2 Activates Epithelial ADAM17: Link to G-Protein-Coupled Receptor 56 (ADGRG1) Signalling.
Autorzy:
Bauer L; College of Biomedical and Life Sciences, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
Edwards J; College of Biomedical and Life Sciences, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
Heil A; College of Biomedical and Life Sciences, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
Dewitt S; College of Biomedical and Life Sciences, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
Biebermann H; Institute of Experimental Pediatric Endocrinology, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
Aeschlimann D; College of Biomedical and Life Sciences, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
Knäuper V; College of Biomedical and Life Sciences, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 16; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Journal Article
MeSH Terms:
Protein Glutamine gamma Glutamyltransferase 2*/metabolism
Receptors, G-Protein-Coupled*/genetics
Receptors, G-Protein-Coupled*/metabolism
Humans ; ADAM17 Protein/genetics ; ADAM17 Protein/metabolism ; ErbB Receptors/metabolism ; Ligands ; Signal Transduction
Czasopismo naukowe
Tytuł:
Discovery of novel 1H-benzo[d]imidazole-4,7-dione based transglutaminase 2 inhibitors as p53 stabilizing anticancer agents in renal cell carcinoma.
Autorzy:
Kim GR; School of Life Sciences, Gwangju Institute of Science and Technology, 123 Cheomdangwagi-ro, Buk-gu, Gwangju 61005, Republic of Korea.
Kang JH; Graduate School of Cancer Science and Policy, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang 10408, Republic of Korea.
Kim HJ; MDbiopharm Corp., 114 Beobwon-ro, Songpa-gu, Seoul 05854, Republic of Korea.
Im E; MDbiopharm Corp., 114 Beobwon-ro, Songpa-gu, Seoul 05854, Republic of Korea.
Bae J; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, 123 Cheomdangwagi-ro, Buk-gu, Gwangju 61005, Republic of Korea.
Kwon WS; Songdang Institute for Cancer Research, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.
Rha SY; Songdang Institute for Cancer Research, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.
Chung HC; MDbiopharm Corp., 114 Beobwon-ro, Songpa-gu, Seoul 05854, Republic of Korea; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.
Cho EY; MDbiopharm Corp., 114 Beobwon-ro, Songpa-gu, Seoul 05854, Republic of Korea. Electronic address: .
Kim SY; Cancer Molecular Biology Branch, Division of Cancer Biology, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang 10408, Republic of Korea. Electronic address: .
Kim YC; School of Life Sciences, Gwangju Institute of Science and Technology, 123 Cheomdangwagi-ro, Buk-gu, Gwangju 61005, Republic of Korea. Electronic address: .
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Źródło:
Bioorganic chemistry [Bioorg Chem] 2024 Feb; Vol. 143, pp. 107061. Date of Electronic Publication: 2023 Dec 25.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Carcinoma, Renal Cell*/drug therapy
Carcinoma, Renal Cell*/pathology
Kidney Neoplasms*/drug therapy
Kidney Neoplasms*/pathology
Protein Glutamine gamma Glutamyltransferase 2*/antagonists & inhibitors
Animals ; Humans ; Cell Line, Tumor ; Imidazoles/therapeutic use ; Molecular Docking Simulation ; Transglutaminases/antagonists & inhibitors ; Transglutaminases/metabolism ; Tumor Suppressor Protein p53/drug effects ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
Tytuł:
Transglutaminase 2 has higher affinity for relaxed than for stretched fibronectin fibers.
Autorzy:
Selcuk K; Department of Health Sciences and Technology, Institute of Translational Medicine, Laboratory of Applied Mechanobiology, ETH Zurich, Gloriastrasse 37-39 GLC G11, CH-8092 Zurich, Switzerland.
Leitner A; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Otto-Stern-Weg 3, CH-8093 Zurich, Switzerland.
Braun L; Department of Health Sciences and Technology, Institute of Translational Medicine, Laboratory of Applied Mechanobiology, ETH Zurich, Gloriastrasse 37-39 GLC G11, CH-8092 Zurich, Switzerland.
Le Blanc F; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Otto-Stern-Weg 3, CH-8093 Zurich, Switzerland.
Pacak P; Department of Health Sciences and Technology, Institute of Translational Medicine, Laboratory of Applied Mechanobiology, ETH Zurich, Gloriastrasse 37-39 GLC G11, CH-8092 Zurich, Switzerland.
Pot S; Department of Health Sciences and Technology, Institute of Translational Medicine, Laboratory of Applied Mechanobiology, ETH Zurich, Gloriastrasse 37-39 GLC G11, CH-8092 Zurich, Switzerland.
Vogel V; Department of Health Sciences and Technology, Institute of Translational Medicine, Laboratory of Applied Mechanobiology, ETH Zurich, Gloriastrasse 37-39 GLC G11, CH-8092 Zurich, Switzerland. Electronic address: .
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Źródło:
Matrix biology : journal of the International Society for Matrix Biology [Matrix Biol] 2024 Jan; Vol. 125, pp. 113-132. Date of Electronic Publication: 2023 Dec 20.
Typ publikacji:
Journal Article
MeSH Terms:
Protein Glutamine gamma Glutamyltransferase 2*
Fibronectins*/metabolism
Transglutaminases/genetics ; Transglutaminases/chemistry ; Transglutaminases/metabolism ; Molecular Docking Simulation ; GTP-Binding Proteins/genetics ; GTP-Binding Proteins/chemistry ; GTP-Binding Proteins/metabolism ; Extracellular Matrix Proteins/metabolism
Czasopismo naukowe
Tytuł:
Targeting gamma-glutamyl transpeptidase: A pleiotropic enzyme involved in glutathione metabolism and in the control of redox homeostasis.
Autorzy:
Mitrić A; Institute of Clinical and Molecular Virology, Friedrich-Alexander University Erlangen-Nürnberg, 91054, Erlangen, Germany.
Castellano I; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131, Naples, Italy; Department of Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Villa Comunale, Naples, Italy. Electronic address: .
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Źródło:
Free radical biology & medicine [Free Radic Biol Med] 2023 Nov 01; Vol. 208, pp. 672-683. Date of Electronic Publication: 2023 Sep 20.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
gamma-Glutamyltransferase*/genetics
gamma-Glutamyltransferase*/metabolism
Neoplasms*
Humans ; Oxidation-Reduction ; Homeostasis ; Glutathione/metabolism
Czasopismo naukowe
Tytuł:
The Emerging Roles of γ-Glutamyl Peptides Produced by γ-Glutamyltransferase and the Glutathione Synthesis System.
Autorzy:
Ikeda Y; Division of Molecular Cell Biology, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga 849-8501, Japan.
Fujii J; Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Yamagata University, 2-2-2 Iidanishi, Yamagata City 990-9585, Japan.
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Źródło:
Cells [Cells] 2023 Dec 13; Vol. 12 (24). Date of Electronic Publication: 2023 Dec 13.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
gamma-Glutamyltransferase*
Peptides*
Animals ; Glutathione/metabolism ; Dipeptides/metabolism ; Amino Acids ; Cysteine ; Glutamate-Cysteine Ligase
Czasopismo naukowe
Tytuł:
Gamma-glutamyl transferase and calculus of kidney incidence: a Mendelian randomization study.
Autorzy:
Li P; Department of Urology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Hai Yun Cang On the 5th Zip, Dongcheng District, Beijing, 10000, China.
Pang Y; Department of Urology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Hai Yun Cang On the 5th Zip, Dongcheng District, Beijing, 10000, China.
He S; Department of Urology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Hai Yun Cang On the 5th Zip, Dongcheng District, Beijing, 10000, China.
Duan J; Department of Urology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Hai Yun Cang On the 5th Zip, Dongcheng District, Beijing, 10000, China.
Gong H; Department of Urology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Hai Yun Cang On the 5th Zip, Dongcheng District, Beijing, 10000, China.
Yan Y; Department of Urology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Hai Yun Cang On the 5th Zip, Dongcheng District, Beijing, 10000, China. .
Shi J; Department of Urology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Hai Yun Cang On the 5th Zip, Dongcheng District, Beijing, 10000, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 09; Vol. 13 (1), pp. 21821. Date of Electronic Publication: 2023 Dec 09.
Typ publikacji:
Journal Article
MeSH Terms:
gamma-Glutamyltransferase*/genetics
Kidney Calculi*/epidemiology
Kidney Calculi*/genetics
Humans ; Genome-Wide Association Study ; Mendelian Randomization Analysis ; Alanine Transaminase ; Alkaline Phosphatase ; Coloring Agents ; Ubiquitin-Protein Ligases ; Kidney
Czasopismo naukowe
Tytuł:
Mildly elevated serum bilirubin and its correlations with lipid levels among male patients undergoing health checkups.
Autorzy:
Bai X; Department of Internal Medicine, Ningxia People's Armed Police Corps Hospital, 895 Qinghe South Street, Yinchuan, 750001, Ningxia Hui Autonomous Region, China. .
Qiao J; Department of Outpatient, Ningxia People's Armed Police Corps Hospital, 895 Qinghe South Street, Yinchuan, 750001, Ningxia Hui Autonomous Region, China.
Zhang H; Department of Outpatient, Ningxia People's Armed Police Corps Hospital, 895 Qinghe South Street, Yinchuan, 750001, Ningxia Hui Autonomous Region, China.
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Źródło:
Lipids in health and disease [Lipids Health Dis] 2023 Dec 04; Vol. 22 (1), pp. 213. Date of Electronic Publication: 2023 Dec 04.
Typ publikacji:
Journal Article
MeSH Terms:
Bilirubin*
gamma-Glutamyltransferase*
Humans ; Male ; Liver Function Tests ; Prognosis ; Lipids
Czasopismo naukowe
Tytuł:
High-Affinity Fluorogenic Substrate for Tissue Transglutaminase Reveals Enzymatic Hysteresis.
Autorzy:
Gates EWJ; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.
Prince-Hallée A; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.
Heidari Y; Dalriada Drug Discovery, Mississauga, Ontario L5N 8G4, Canada.
Sedighi A; Dalriada Drug Discovery, Mississauga, Ontario L5N 8G4, Canada.
Keillor JW; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.
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Źródło:
Biochemistry [Biochemistry] 2023 Nov 07; Vol. 62 (21), pp. 3085-3095. Date of Electronic Publication: 2023 Oct 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Protein Glutamine gamma Glutamyltransferase 2*
Fluorescent Dyes*
Humans ; Isoenzymes/metabolism ; Transglutaminases ; Binding Sites
Czasopismo naukowe
Tytuł:
The relationship between serum γ-glutamyltransferase (GGT) and diabetic nephropathy in patients with type 2 diabetes mellitus: a cross-sectional study.
Autorzy:
Dai H; Department of Endocrinology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, No.109, Xueyuanxi Road, Wenzhou, 325000, Zhejiang, China.
Zhu L; Department of Rehabilitation, Zhejiang Chinese Medical University Affiliated Wenzhou Hospital of Traditional Chinese Medicine, No.9 Jiaowei Road, Wenzhou, 325000, Zhejiang, China. .
Pan B; Department of Endocrinology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, No.109, Xueyuanxi Road, Wenzhou, 325000, Zhejiang, China.
Li H; Department of Endocrinology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, No.109, Xueyuanxi Road, Wenzhou, 325000, Zhejiang, China.
Dai Z; Department of Endocrinology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, No.109, Xueyuanxi Road, Wenzhou, 325000, Zhejiang, China.
Su X; Department of Endocrinology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, No.109, Xueyuanxi Road, Wenzhou, 325000, Zhejiang, China.
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Źródło:
Clinical and experimental medicine [Clin Exp Med] 2023 Nov; Vol. 23 (7), pp. 3619-3630. Date of Electronic Publication: 2023 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*/complications
Diabetic Nephropathies*/diagnosis
gamma-Glutamyltransferase*
Female ; Humans ; Male ; Cross-Sectional Studies ; Glomerular Filtration Rate
Czasopismo naukowe
Tytuł:
Study of tissue transglutaminase spliced variants expressed in THP-1 derived macrophages exhibiting distinct functional phenotypes.
Autorzy:
Arbildi P; Unidad Asociada de Inmunología, Instituto de Química Biológica (IQB), Facultad de Ciencias, Universidad de la República, Iguá 4225, Montevideo 11400, Uruguay; Area Inmunología, Departamento de Biociencias (DEPBIO), Facultad de Química, Universidad de la República, General Flores 2124, Montevideo 11800, Uruguay; Laboratorio de Inmunología, Instituto de Higiene 'Prof. Arnoldo Berta', Universidad de la República, Alfredo Navarro 3051, Montevideo 11600, Uruguay. Electronic address: .
Calvo F; Unidad Asociada de Inmunología, Instituto de Química Biológica (IQB), Facultad de Ciencias, Universidad de la República, Iguá 4225, Montevideo 11400, Uruguay; Area Inmunología, Departamento de Biociencias (DEPBIO), Facultad de Química, Universidad de la República, General Flores 2124, Montevideo 11800, Uruguay; Laboratorio de Inmunología, Instituto de Higiene 'Prof. Arnoldo Berta', Universidad de la República, Alfredo Navarro 3051, Montevideo 11600, Uruguay.
Macías V; Unidad Asociada de Inmunología, Instituto de Química Biológica (IQB), Facultad de Ciencias, Universidad de la República, Iguá 4225, Montevideo 11400, Uruguay; Area Inmunología, Departamento de Biociencias (DEPBIO), Facultad de Química, Universidad de la República, General Flores 2124, Montevideo 11800, Uruguay; Laboratorio de Inmunología, Instituto de Higiene 'Prof. Arnoldo Berta', Universidad de la República, Alfredo Navarro 3051, Montevideo 11600, Uruguay.
Rodríguez-Camejo C; Unidad Asociada de Inmunología, Instituto de Química Biológica (IQB), Facultad de Ciencias, Universidad de la República, Iguá 4225, Montevideo 11400, Uruguay; Area Inmunología, Departamento de Biociencias (DEPBIO), Facultad de Química, Universidad de la República, General Flores 2124, Montevideo 11800, Uruguay; Laboratorio de Inmunología, Instituto de Higiene 'Prof. Arnoldo Berta', Universidad de la República, Alfredo Navarro 3051, Montevideo 11600, Uruguay. Electronic address: .
Sóñora C; Unidad Asociada de Inmunología, Instituto de Química Biológica (IQB), Facultad de Ciencias, Universidad de la República, Iguá 4225, Montevideo 11400, Uruguay; Area Inmunología, Departamento de Biociencias (DEPBIO), Facultad de Química, Universidad de la República, General Flores 2124, Montevideo 11800, Uruguay; Laboratorio de Inmunología, Instituto de Higiene 'Prof. Arnoldo Berta', Universidad de la República, Alfredo Navarro 3051, Montevideo 11600, Uruguay; Escuela Universitaria de Tecnología Médica (EUTM), Facultad de Medicina, Universidad de la República, Alfredo Navarro S/N, Montevideo 11600, Uruguay. Electronic address: .
Hernández A; Unidad Asociada de Inmunología, Instituto de Química Biológica (IQB), Facultad de Ciencias, Universidad de la República, Iguá 4225, Montevideo 11400, Uruguay; Area Inmunología, Departamento de Biociencias (DEPBIO), Facultad de Química, Universidad de la República, General Flores 2124, Montevideo 11800, Uruguay; Laboratorio de Inmunología, Instituto de Higiene 'Prof. Arnoldo Berta', Universidad de la República, Alfredo Navarro 3051, Montevideo 11600, Uruguay. Electronic address: .
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Źródło:
Immunobiology [Immunobiology] 2023 Nov; Vol. 228 (6), pp. 152752. Date of Electronic Publication: 2023 Oct 02.
Typ publikacji:
Journal Article
MeSH Terms:
Macrophages*/metabolism
Protein Glutamine gamma Glutamyltransferase 2*
Humans ; Interleukin-4/metabolism ; Monocytes/metabolism ; Phenotype ; THP-1 Cells/metabolism
Czasopismo naukowe
Tytuł:
Metabolic characterisation of transglutaminase 2 inhibitor effects in breast cancer cell lines.
Autorzy:
Gallo M; Department of Medicine and Surgery, University of Parma, Italy.
Ferrari E; Department of Medicine and Surgery, University of Parma, Italy.
Terrazzan A; Department of Translational Medicine, University of Ferrara, Italy.
Brugnoli F; Department of Translational Medicine, University of Ferrara, Italy.
Spisni A; Department of Medicine and Surgery, University of Parma, Italy.
Taccioli C; Department of Animal Medicine, Production and Health (MAPS), University of Padua, Italy.
Aguiari G; Department of Neuroscience and Rehabilitation, University of Ferrara, Italy.
Trentini A; Department of Environmental Sciences and Prevention, University of Ferrara, Italy.
Volinia S; Department of Translational Medicine, University of Ferrara, Italy.
Keillor JW; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Canada.
Bergamini CM; Department of Neuroscience and Rehabilitation, University of Ferrara, Italy.
Bianchi N; Department of Translational Medicine, University of Ferrara, Italy.
Pertinhez TA; Department of Medicine and Surgery, University of Parma, Italy.
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Źródło:
The FEBS journal [FEBS J] 2023 Nov; Vol. 290 (22), pp. 5411-5433. Date of Electronic Publication: 2023 Aug 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Protein Glutamine gamma Glutamyltransferase 2*
Breast Neoplasms*/metabolism
Humans ; Female ; MCF-7 Cells ; Apoptosis ; Metabolomics ; Cell Line, Tumor ; Transglutaminases/metabolism
Czasopismo naukowe
Tytuł:
Gamma-glutamyl transferase to high-density lipoprotein cholesterol ratio is a more powerful marker than TyG index for predicting metabolic syndrome in patients with type 2 diabetes mellitus.
Autorzy:
Gong S; Department of Medicine, Jishou University, Jishou, China.
Gan S; Department of Endocrinology, The First People's Hospital of Changde City, Changde, China.
Zhang Y; Department of Medicine, Jishou University, Jishou, China.
Zhou H; Department of Endocrinology, The First People's Hospital of Changde City, Changde, China.
Zhou Q; Department of Science and Education, The First People's Hospital of Changde City, Changde, China.
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Źródło:
Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2023 Oct 03; Vol. 14, pp. 1248614. Date of Electronic Publication: 2023 Oct 03 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Cholesterol, HDL*/blood
Diabetes Mellitus, Type 2*/blood
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/diagnosis
gamma-Glutamyltransferase*/blood
Metabolic Syndrome*/blood
Metabolic Syndrome*/complications
Metabolic Syndrome*/diagnosis
Metabolic Syndrome*/epidemiology
Humans ; Blood Glucose/analysis ; Cross-Sectional Studies ; Triglycerides/blood ; Insulin Resistance
Czasopismo naukowe
Tytuł:
Biochemical and Functional Characterization of the Three Zebrafish Transglutaminases 2.
Autorzy:
Lisetto M; Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.
Fattorini M; Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.
Lanza A; Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.
Gerdol M; Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.
Griffin M; College of Health and Life Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, UK.
Wang Z; College of Health and Life Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, UK.
Ferrara F; Specifica a Q2 Solutions Company, Santa Fe, NM 87501, USA.
Sblattero D; Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 27; Vol. 24 (15). Date of Electronic Publication: 2023 Jul 27.
Typ publikacji:
Journal Article
MeSH Terms:
Protein Glutamine gamma Glutamyltransferase 2*/chemistry
Protein Glutamine gamma Glutamyltransferase 2*/classification
Protein Glutamine gamma Glutamyltransferase 2*/genetics
Zebrafish*/genetics
Zebrafish*/metabolism
Zebrafish Proteins*/chemistry
Zebrafish Proteins*/classification
Zebrafish Proteins*/genetics
Animals ; Humans ; Apoptosis/genetics ; Catalysis ; Cell Adhesion ; Fibroblasts ; Gene Expression ; HEK293 Cells ; Phylogeny ; Protein Conformation ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics
Czasopismo naukowe
Tytuł:
Microglial transglutaminase 2 deficiency causes impaired synaptic remodelling and cognitive deficits in mice.
Autorzy:
Liu C; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.
Gao X; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, China.
Shi RX; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, China.
Wang YY; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, China.
He XC; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.
Du HZ; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.
Hu B; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, China.
Jiao J; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, China.
Liu CM; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, China.
Teng ZQ; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, China.
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Źródło:
Cell proliferation [Cell Prolif] 2023 Sep; Vol. 56 (9), pp. e13439. Date of Electronic Publication: 2023 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
Microglia*/metabolism
Protein Glutamine gamma Glutamyltransferase 2*
Mice ; Animals ; Neurons/metabolism ; Brain ; Cognition
Czasopismo naukowe
Tytuł:
Cell-Impermeable Inhibitors Confirm That Intracellular Human Transglutaminase 2 Is Responsible for the Transglutaminase-Associated Cancer Phenotype.
Autorzy:
Gates EWJ; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Calvert ND; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Cundy NJ; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Brugnoli F; Department of Translational Medicine, University of Ferrara, 44021 Ferrara, Italy.
Navals P; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Kirby A; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Bianchi N; Department of Translational Medicine, University of Ferrara, 44021 Ferrara, Italy.
Adhikary G; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Shuhendler AJ; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Eckert RL; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Keillor JW; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 08; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 08.
Typ publikacji:
Journal Article
MeSH Terms:
Protein Glutamine gamma Glutamyltransferase 2*
Neoplasms*
Humans ; Transglutaminases ; Fluorescent Dyes ; Phenotype
Czasopismo naukowe
Tytuł:
Discovery and Characterization of PROTACs Targeting Tissue Transglutaminase (TG2).
Autorzy:
Valdivia A; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, United States.
Vagadia PP; Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
Guo G; WuXi AppTec, Shanghai 200131, People's Republic of China.
O'Brien E; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, United States.
Matei D; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, United States.; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, United States.; Jesse Brown VA Medical Center, Chicago, Illinois 60612, United States.
Schiltz GE; Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, United States.; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, United States.
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Źródło:
Journal of medicinal chemistry [J Med Chem] 2023 Jul 27; Vol. 66 (14), pp. 9445-9465. Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Protein Glutamine gamma Glutamyltransferase 2*
Transglutaminases*
Female ; Humans ; Proteolysis Targeting Chimera ; GTP-Binding Proteins/metabolism ; Cell Adhesion
Czasopismo naukowe
Tytuł:
Transglutaminase 2 Facilitates Murine Wound Healing in a Strain-Dependent Manner.
Autorzy:
Yiu TW; Victor Chang Cardiac Research Institute, Darlinghurst, NSW 2010, Australia.
Holman SR; Victor Chang Cardiac Research Institute, Darlinghurst, NSW 2010, Australia.
Kaidonis X; Victor Chang Cardiac Research Institute, Darlinghurst, NSW 2010, Australia.
Graham RM; Victor Chang Cardiac Research Institute, Darlinghurst, NSW 2010, Australia.; School of Clinical Medicine, UNSW Medicine and Health, University of New South Wales Sydney, Kensington, NSW 2052, Australia.
Iismaa SE; Victor Chang Cardiac Research Institute, Darlinghurst, NSW 2010, Australia.; School of Clinical Medicine, UNSW Medicine and Health, University of New South Wales Sydney, Kensington, NSW 2052, Australia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 14; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:
Journal Article
MeSH Terms:
Protein Glutamine gamma Glutamyltransferase 2*
GTP-Binding Proteins*/metabolism
Mice ; Animals ; Mice, Inbred C57BL ; Wound Healing/genetics ; Mice, Knockout ; Syndecans/metabolism ; Integrins/metabolism ; RNA, Messenger ; Transglutaminases/metabolism
Czasopismo naukowe
Tytuł:
The glutathione import system satisfies the Staphylococcus aureus nutrient sulfur requirement and promotes interspecies competition.
Autorzy:
Lensmire JM; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America.
Wischer MR; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America.
Kraemer-Zimpel C; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America.
Kies PJ; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America.
Sosinski L; Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan, United States of America.
Ensink E; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, United States of America.
Dodson JP; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America.
Shook JC; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America.
Delekta PC; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America.
Cooper CC; Department of Medicine, Division of Infectious Disease, Michigan State University, East Lansing, Michigan, United States of America.
Havlichek DH Jr; Department of Medicine, Division of Infectious Disease, Michigan State University, East Lansing, Michigan, United States of America.
Mulks MH; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America.
Lunt SY; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, United States of America.; Department of Chemical Engineering and Materials Science, Michigan State University, East Lansing, Michigan, United States of America.
Ravi J; Department of Biomedical Informatics, Center for Health Artificial Intelligence, University of Colorado Anschutz, Aurora, Colorado, United States of America.
Hammer ND; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2023 Jul 07; Vol. 19 (7), pp. e1010834. Date of Electronic Publication: 2023 Jul 07 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Staphylococcus aureus*/genetics
gamma-Glutamyltransferase*/genetics
Humans ; Glutathione Disulfide ; Glutathione/genetics ; Sulfur
Czasopismo naukowe
Tytuł:
Redesign of γ-glutamyl transpeptidase from Bacillus subtilis for high-level production of L-theanine by cavity topology engineering.
Autorzy:
Zhang Z; The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, Jiangsu, China.
Long M; The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, Jiangsu, China.
Zheng N; The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, Jiangsu, China.
Deng Y; The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, Jiangsu, China.
Wang Q; The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, Jiangsu, China.
Osire T; Faculty of Biology, Shenzhen MSU-BIT University, Shenzhen, 518172, Guangdong, China.
Xia X; The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, Jiangsu, China. .
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Źródło:
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2023 Jun; Vol. 107 (11), pp. 3551-3564. Date of Electronic Publication: 2023 Apr 26.
Typ publikacji:
Journal Article
MeSH Terms:
Bacillus subtilis*/metabolism
gamma-Glutamyltransferase*/genetics
gamma-Glutamyltransferase*/chemistry
gamma-Glutamyltransferase*/metabolism
Glutamates ; Biocatalysis
Czasopismo naukowe

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