Temat: "gene dosage" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: APOE ε4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in cognitively unimpaired elderly.
Autorzy:: Snellman A; Turku PET Centre, University of Turku, Turku University Hospital, Kiinamyllynkatu 4-8, 20520, Turku, Finland. .; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden. .
Ekblad LL; Turku PET Centre, University of Turku, Turku University Hospital, Kiinamyllynkatu 4-8, 20520, Turku, Finland.
Tuisku J; Turku PET Centre, University of Turku, Turku University Hospital, Kiinamyllynkatu 4-8, 20520, Turku, Finland.
Koivumäki M; Turku PET Centre, University of Turku, Turku University Hospital, Kiinamyllynkatu 4-8, 20520, Turku, Finland.
Ashton NJ; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Centre for Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway.; Department of Old Age Psychiatry, Maurice Wohl Clinical Neuroscience Institute, King's College London, London, UK.; NIHR Biomedical Research Centre for Mental Health & Biomedical Research Unit for Dementia at South London & Maudsley NHS Foundation, London, UK.
Lantero-Rodriguez J; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.
Karikari TK; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Helin S; Turku PET Centre, University of Turku, Turku University Hospital, Kiinamyllynkatu 4-8, 20520, Turku, Finland.
Bucci M; Turku PET Centre, University of Turku, Turku University Hospital, Kiinamyllynkatu 4-8, 20520, Turku, Finland.; Theme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden.; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
Löyttyniemi E; Department of Biostatistics, University of Turku, Turku, Finland.
Parkkola R; Department of Radiology, Turku University Hospital, University of Turku, Turku, Finland.
Karrasch M; Department of Psychology, Åbo Akademi University, Turku, Finland.
Schöll M; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.
Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; UK Dementia Research Institute at UCL, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.
Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
Rinne JO; Turku PET Centre, University of Turku, Turku University Hospital, Kiinamyllynkatu 4-8, 20520, Turku, Finland.; InFLAMES Research Flagship Center, University of Turku, Turku, Finland.; Pokaż więcej
Źródło:: Alzheimer's research & therapy [Alzheimers Res Ther] 2023 Apr 04; Vol. 15 (1), pp. 71. Date of Electronic Publication: 2023 Apr 04.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Alzheimer Disease*/genetics
Amyloid beta-Peptides*/metabolism
Apolipoprotein E4*/genetics
Gene Dosage*
Aged ; Humans ; Biomarkers ; Genotype ; Neuroinflammatory Diseases ; Positron-Emission Tomography ; Receptors, GABA/genetics

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Skocz do pozycji: 2.

Tytuł:: Alpha globin gene copy number and hypertension risk among Black Americans.
Autorzy:: Ruhl AP; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.; Pulmonary Branch, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America.
Jeffries N; Office of Biostatistics Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America.
Yang Y; Division of Blood Diseases and Resources, National Heart, Lung, and Blood Institute, Rockville, Maryland, United States of America.
Gutierrez OM; Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Muntner P; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Naik RP; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Pecker LH; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Mott BT; University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America.
Zakai NA; Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont, United States of America.; Department of Pathology & Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont, United States of America.
Safford MM; Department of Medicine, Weill Cornell Medicine, New York, New York, United States of America.
Lange LA; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado, Denver, Colorado, United States of America.
Winkler CA; Basic Research Laboratory, National Cancer Institute, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Irvin MR; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Cushman M; Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont, United States of America.; Department of Pathology & Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont, United States of America.
Ackerman HC; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Jul 14; Vol. 17 (7), pp. e0271031. Date of Electronic Publication: 2022 Jul 14 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: Gene Dosage*/genetics
Hypertension*/genetics
alpha-Globins*/genetics
Blood Pressure/genetics ; Endothelial Cells ; Humans ; Nitric Oxide/therapeutic use ; Prospective Studies ; Risk Factors

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Skocz do pozycji: 3.

Tytuł:: In-Depth Sequence Analysis of Bread Wheat VRN1 Genes.
Autorzy:: Strejčková B; Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany of the Czech Academy of Sciences, 77900 Olomouc, Czech Republic.; Department of Cell Biology and Genetics, Faculty of Science, Palacký University, 78371 Olomouc, Czech Republic.
Milec Z; Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany of the Czech Academy of Sciences, 77900 Olomouc, Czech Republic.
Holušová K; Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany of the Czech Academy of Sciences, 77900 Olomouc, Czech Republic.
Cápal P; Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany of the Czech Academy of Sciences, 77900 Olomouc, Czech Republic.
Vojtková T; Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany of the Czech Academy of Sciences, 77900 Olomouc, Czech Republic.
Čegan R; Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany of the Czech Academy of Sciences, 77900 Olomouc, Czech Republic.; Department of Plant Developmental Genetics, Institute of Biophysics of the Czech Academy of Sciences, 61200 Brno, Czech Republic.
Šafář J; Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany of the Czech Academy of Sciences, 77900 Olomouc, Czech Republic.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Nov 13; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 13.
Typ publikacji:: Journal Article
MeSH Terms:: Alleles*
Gene Dosage*
Genetic Variation*
Polyploidy*
Repressor Proteins/*genetics
Triticum/*genetics
Alternative Splicing ; Bread ; Mutagenesis, Insertional ; Sequence Analysis, DNA

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Skocz do pozycji: 4.

Tytuł:: Whole genome copy number analyses reveal a highly aberrant genome in TP53 mutant lung adenocarcinoma tumors.
Autorzy:: Bjaanæs MM; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital-The Norwegian Radium Hospital, Oslo, Norway. .; Department of Oncology, Oslo University Hospital, 4950 Nydalen, Oslo, Norway. .
Nilsen G; Department of Computer Science, University of Oslo, Oslo, Norway.; Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Halvorsen AR; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital-The Norwegian Radium Hospital, Oslo, Norway.
Russnes HG; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital-The Norwegian Radium Hospital, Oslo, Norway.; Department of Pathology, Oslo University Hospital, Oslo, Norway.
Solberg S; Department of Cardiothoracic Surgery, Oslo University Hospital, Oslo, Norway.
Jørgensen L; Department of Cardiothoracic Surgery, Oslo University Hospital, Oslo, Norway.
Brustugun OT; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital-The Norwegian Radium Hospital, Oslo, Norway.; Section of Oncology, Vestre Viken Hospital, Drammen, Norway.
Lingjærde OC; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital-The Norwegian Radium Hospital, Oslo, Norway.; Department of Computer Science, University of Oslo, Oslo, Norway.; Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Helland Å; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital-The Norwegian Radium Hospital, Oslo, Norway.; Department of Oncology, Oslo University Hospital, 4950 Nydalen, Oslo, Norway.; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2021 Oct 09; Vol. 21 (1), pp. 1089. Date of Electronic Publication: 2021 Oct 09.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Dosage*
Genes, p53*
Adenocarcinoma of Lung/*genetics
Carcinoma, Non-Small-Cell Lung/*genetics
Lung Neoplasms/*genetics
Adenocarcinoma of Lung/pathology ; Alleles ; Carcinoma, Non-Small-Cell Lung/pathology ; Chromosomes, Human, Pair 7 ; Chromosomes, Human, Pair 9 ; Class I Phosphatidylinositol 3-Kinases/genetics ; DNA Copy Number Variations ; Ex-Smokers ; Female ; Gene Expression ; Genes, erbB-1/genetics ; Genes, ras/genetics ; Humans ; Lung Neoplasms/pathology ; Male ; Non-Smokers ; Polymorphism, Single Nucleotide ; Signal Transduction/genetics ; Smokers ; TOR Serine-Threonine Kinases/genetics

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Skocz do pozycji: 5.

Tytuł:: Dyrk1a gene dosage in glutamatergic neurons has key effects in cognitive deficits observed in mouse models of MRD7 and Down syndrome.
Autorzy:: Brault V; Université de Strasbourg, CNRS, INSERM, Institut de Génétique et de Biologie Moléculaire et Cellulaire, IGBMC, Illkirch, France.
Nguyen TL; Université de Strasbourg, CNRS, INSERM, Institut de Génétique et de Biologie Moléculaire et Cellulaire, IGBMC, Illkirch, France.
Flores-Gutiérrez J; Université de Strasbourg, CNRS, INSERM, Institut de Génétique et de Biologie Moléculaire et Cellulaire, IGBMC, Illkirch, France.
Iacono G; Department of Molecular Biology, Radboud Institute for Molecular Life Sciences, Radboud University, Nijmegen, the Netherlands.
Birling MC; Université de Strasbourg, CNRS, INSERM, CELPHEDIA, PHENOMIN, Institut Clinique de la Souris, Illkirch, France.
Lalanne V; Université de Strasbourg, CNRS, INSERM, CELPHEDIA, PHENOMIN, Institut Clinique de la Souris, Illkirch, France.
Meziane H; Université de Strasbourg, CNRS, INSERM, CELPHEDIA, PHENOMIN, Institut Clinique de la Souris, Illkirch, France.
Manousopoulou A; Institute for Life Sciences, University of Southampton, School of Medicine, Southampton, United Kingdom.
Pavlovic G; Université de Strasbourg, CNRS, INSERM, CELPHEDIA, PHENOMIN, Institut Clinique de la Souris, Illkirch, France.
Lindner L; Université de Strasbourg, CNRS, INSERM, CELPHEDIA, PHENOMIN, Institut Clinique de la Souris, Illkirch, France.
Selloum M; Université de Strasbourg, CNRS, INSERM, Institut de Génétique et de Biologie Moléculaire et Cellulaire, IGBMC, Illkirch, France.
Sorg T; Université de Strasbourg, CNRS, INSERM, Institut de Génétique et de Biologie Moléculaire et Cellulaire, IGBMC, Illkirch, France.
Yu E; The Children's Guild Foundation Down Syndrome Research Program, Genetics and Genomics Program and Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, New York, United States of America.; Genetics, Genomics and Bioinformatics Program, State University of New York At Buffalo, Buffalo, New York, United States of America.
Garbis SD; Institute for Life Sciences, University of Southampton, School of Medicine, Southampton, United Kingdom.
Hérault Y; Université de Strasbourg, CNRS, INSERM, Institut de Génétique et de Biologie Moléculaire et Cellulaire, IGBMC, Illkirch, France.; Université de Strasbourg, CNRS, INSERM, CELPHEDIA, PHENOMIN, Institut Clinique de la Souris, Illkirch, France.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2021 Sep 29; Vol. 17 (9), pp. e1009777. Date of Electronic Publication: 2021 Sep 29 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Dosage*
Autistic Disorder/*genetics
Cognition Disorders/*genetics
Down Syndrome/*genetics
Glutamic Acid/*metabolism
Intellectual Disability/*genetics
Neurons/*metabolism
Speech Disorders/*genetics
Animals ; Brain/pathology ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism ; Cognition Disorders/complications ; Disease Models, Animal ; Down Syndrome/complications ; Gene Expression Regulation ; Humans ; Mice ; Mice, Transgenic ; Proteomics/methods ; Synaptic Transmission/genetics ; Transcription, Genetic

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Skocz do pozycji: 6.

Tytuł:: In vitro culture of freshly isolated Trypanosoma brucei brucei bloodstream forms results in gene copy-number changes.
Autorzy:: Mulindwa J; Department of Biochemistry and Sports Science, College of Natural Sciences, Makerere University, Kampala, Uganda.
Ssentamu G; School of Biosecurity, Biotechnical and Laboratory Sciences, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Matovu E; School of Biosecurity, Biotechnical and Laboratory Sciences, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Kamanyi Marucha K; Heidelberg University Centre for Molecular Biology (ZMBH), Heidelberg, Germany.
Aresta-Branco F; Division of Immune Diversity, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.
Helbig C; Heidelberg University Centre for Molecular Biology (ZMBH), Heidelberg, Germany.
Clayton C; Heidelberg University Centre for Molecular Biology (ZMBH), Heidelberg, Germany.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Sep 13; Vol. 15 (9), pp. e0009738. Date of Electronic Publication: 2021 Sep 13 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Dosage*
Cattle Diseases/*parasitology
Trypanosoma brucei brucei/*genetics
Trypanosoma brucei brucei/*physiology
Trypanosomiasis, African/*veterinary
Animals ; Cattle ; Cattle Diseases/blood ; Protozoan Proteins ; Trypanosomiasis, African/blood ; Trypanosomiasis, African/parasitology

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Skocz do pozycji: 7.

Tytuł:: Increased gene expression and copy number of mutated bla KPC lead to high-level ceftazidime/avibactam resistance in Klebsiella pneumoniae.
Autorzy:: Sun L; National Clinical Research Center for Respiratory Diseases, China-Japan Friendship Hospital, Capital Medical University, Beijing, China.; Laboratory of Clinical Microbiology and Infectious Diseases, Department of Pulmonary and Critical Care Medicine, Center for Respiratory Diseases, China-Japan Friendship Hospital, Beijing, China.; National Clinical Research Center of Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Science, Beijing, China.
Li H; Laboratory of Clinical Microbiology and Infectious Diseases, Department of Pulmonary and Critical Care Medicine, Center for Respiratory Diseases, China-Japan Friendship Hospital, Beijing, China.; National Clinical Research Center of Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Science, Beijing, China.
Wang Q; Department of Clinical Laboratory, Peking University People's Hospital, Beijing, China.
Liu Y; Laboratory of Clinical Microbiology and Infectious Diseases, Department of Pulmonary and Critical Care Medicine, Center for Respiratory Diseases, China-Japan Friendship Hospital, Beijing, China. .; National Clinical Research Center of Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Science, Beijing, China. .
Cao B; National Clinical Research Center for Respiratory Diseases, China-Japan Friendship Hospital, Capital Medical University, Beijing, China. caobin_.; Laboratory of Clinical Microbiology and Infectious Diseases, Department of Pulmonary and Critical Care Medicine, Center for Respiratory Diseases, China-Japan Friendship Hospital, Beijing, China. caobin_.; National Clinical Research Center of Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Science, Beijing, China. caobin_.; Tsinghua University-Peking University Joint Center for Life Sciences, Beijing, China. caobin_.; Pokaż więcej
Źródło:: BMC microbiology [BMC Microbiol] 2021 Aug 19; Vol. 21 (1), pp. 230. Date of Electronic Publication: 2021 Aug 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Dosage*
Gene Expression*
Mutation*
Anti-Bacterial Agents/*pharmacology
Azabicyclo Compounds/*pharmacology
Ceftazidime/*pharmacology
Drug Resistance, Multiple, Bacterial/*genetics
Klebsiella pneumoniae/*drug effects
Klebsiella pneumoniae/*genetics
beta-Lactamases/*genetics
Drug Combinations ; Humans ; Klebsiella Infections/microbiology ; Klebsiella pneumoniae/enzymology ; Microbial Sensitivity Tests

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Skocz do pozycji: 8.

Tytuł:: The Changes in the p53 Protein across the Animal Kingdom Point to Its Involvement in Longevity.
Autorzy:: Bartas M; Department of Biology and Ecology, Faculty of Science, University of Ostrava, 71000 Ostrava, Czech Republic.
Brázda V; Institute of Biophysics of the Czech Academy of Sciences, 61265 Brno, Czech Republic.
Volná A; Department of Physics, Faculty of Science, University of Ostrava, Chittussiho 10, 71000 Ostrava, Czech Republic.
Červeň J; Department of Biology and Ecology, Faculty of Science, University of Ostrava, 71000 Ostrava, Czech Republic.
Pečinka P; Department of Biology and Ecology, Faculty of Science, University of Ostrava, 71000 Ostrava, Czech Republic.
Zawacka-Pankau JE; Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.; Center for Hematology and Regenerative Medicine, Department of Medicine, Huddinge, Karolinska Institute, SE 171-74 Stockholm, Sweden.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Aug 07; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 07.
Typ publikacji:: Journal Article
MeSH Terms:: Databases, Genetic*
Gene Dosage*
Longevity*
Models, Molecular*
Animals ; Protein Domains ; Protein Structure, Secondary ; Species Specificity ; Tumor Suppressor Protein p53/chemistry ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism

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Skocz do pozycji: 9.

Tytuł:: Modest changes in Spi1 dosage reveal the potential for altered microglial function as seen in Alzheimer's disease.
Autorzy:: Jones RE; Division of Infection and Immunity, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ, UK.
Andrews R; Division of Infection and Immunity, Cardiff University, Cardiff, UK.; Systems Immunity Research Institute, Cardiff University, Cardiff, UK.
Holmans P; Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.
Hill M; UK Dementia Research Institute at Cardiff, Cardiff University, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ, UK.
Taylor PR; Division of Infection and Immunity, Cardiff University, Cardiff, UK. .; UK Dementia Research Institute at Cardiff, Cardiff University, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ, UK. .; Systems Immunity Research Institute, Cardiff University, Cardiff, UK. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jul 22; Vol. 11 (1), pp. 14935. Date of Electronic Publication: 2021 Jul 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Dosage*
Gene Regulatory Networks*
Alzheimer Disease/*genetics
Gene Expression Profiling/*methods
Microglia/*cytology
Proto-Oncogene Proteins/*genetics
Trans-Activators/*genetics
Animals ; Humans ; Interferons/metabolism ; Mice ; Microglia/metabolism ; Polymorphism, Single Nucleotide ; Primary Cell Culture ; Sequence Analysis, RNA ; Signal Transduction

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Skocz do pozycji: 10.

Tytuł:: Identification of pan-cancer Ras pathway activation with deep learning.
Autorzy:: Li X; School of Artificial Intelligence, Jilin University.
Li S; School of Computer Science, Northeast Normal University.
Wang Y; School of Computer Science, Northeast Normal University.
Zhang S; Department of Computer science, City University of Hong Kong, Hong Kong SAR.
Wong KC; Department of Computer science, City University of Hong Kong, Hong Kong SAR.; Pokaż więcej
Źródło:: Briefings in bioinformatics [Brief Bioinform] 2021 Jul 20; Vol. 22 (4).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Deep Learning*
Gene Dosage*
Neoplasm Proteins*/genetics
Neoplasm Proteins*/metabolism
Neoplasms*/epidemiology
Neoplasms*/genetics
Programming Languages*
ras Proteins*/genetics
ras Proteins*/metabolism
Signal Transduction/*genetics
Humans ; Mutation ; RNA-Seq

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Skocz do pozycji: 11.

Tytuł:: Reduced odds of diabetes associated with high plasma salivary α-amylase activity in Qatari women: a cross-sectional study.
Autorzy:: Al-Akl NS; Diabetes Research Center, Qatar Biomedical Research Institute (QBRI), Qatar Foundation, Hamad Bin Khalifa University (HBKU), PO Box: 34110, Doha, Qatar.
Thompson RI; Diabetes Research Center, Qatar Biomedical Research Institute (QBRI), Qatar Foundation, Hamad Bin Khalifa University (HBKU), PO Box: 34110, Doha, Qatar.
Arredouani A; Diabetes Research Center, Qatar Biomedical Research Institute (QBRI), Qatar Foundation, Hamad Bin Khalifa University (HBKU), PO Box: 34110, Doha, Qatar. .; College of Health and Life Sciences, Qatar Foundation, Hamad Bin Khalifa University (HBKU), Doha, Qatar. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jun 01; Vol. 11 (1), pp. 11495. Date of Electronic Publication: 2021 Jun 01.
Typ publikacji:: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Dosage*
Sex Characteristics*
Diabetes Mellitus/*blood
Salivary alpha-Amylases/*blood
Adult ; Diabetes Mellitus/epidemiology ; Diabetes Mellitus/genetics ; Female ; Humans ; Male ; Middle Aged ; Prevalence ; Qatar/epidemiology ; Salivary alpha-Amylases/genetics

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Skocz do pozycji: 12.

Tytuł:: Copy number-dependent DNA methylation of the Pyricularia oryzae MAGGY retrotransposon is triggered by DNA damage.
Autorzy:: Van Vu B; Laboratory of Cell Function and Structure, Graduate School of Agricultural Science, Kobe University, Nada Kobe, Japan.
Nguyen Q; Laboratory of Cell Function and Structure, Graduate School of Agricultural Science, Kobe University, Nada Kobe, Japan.
Kondo-Takeoka Y; Laboratory of Cell Function and Structure, Graduate School of Agricultural Science, Kobe University, Nada Kobe, Japan.
Murata T; Laboratory of Cell Function and Structure, Graduate School of Agricultural Science, Kobe University, Nada Kobe, Japan.
Kadotani N; Laboratory of Cell Function and Structure, Graduate School of Agricultural Science, Kobe University, Nada Kobe, Japan.
Thi Nguyen G; Laboratory of Cell Function and Structure, Graduate School of Agricultural Science, Kobe University, Nada Kobe, Japan.
Arazoe T; Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, Noda, Chiba, Japan.
Ohsato S; Graduate School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan.
Nakayashiki H; Laboratory of Cell Function and Structure, Graduate School of Agricultural Science, Kobe University, Nada Kobe, Japan. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2021 Mar 19; Vol. 4 (1), pp. 351. Date of Electronic Publication: 2021 Mar 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Damage*
DNA Methylation*
Gene Dosage*
Retroelements*
Ascomycota/*genetics
Fungal Proteins/*genetics
Ascomycota/metabolism ; Fungal Proteins/metabolism ; Gene Expression Regulation, Fungal ; Mutation ; RNA Interference ; Rad51 Recombinase/genetics ; Rad51 Recombinase/metabolism ; Recombinational DNA Repair
SCR Organism:: Pyricularia oryzae

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Skocz do pozycji: 13.

Tytuł:: Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases.
Autorzy:: Ye T; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Center for Stem Cell Research, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, HKUST Shenzhen Research Institute; Shenzhen-Hong Kong Institute of Brain Science, 518057, Shenzhen, Guangdong, China.; The Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science, 518055, Shenzhen, Guangdong, China.
Duan Y; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Center for Stem Cell Research, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.
Tsang HWS; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Center for Stem Cell Research, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.
Xu H; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Center for Stem Cell Research, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.
Chen Y; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Center for Stem Cell Research, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, HKUST Shenzhen Research Institute; Shenzhen-Hong Kong Institute of Brain Science, 518057, Shenzhen, Guangdong, China.; The Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science, 518055, Shenzhen, Guangdong, China.
Cao H; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Center for Stem Cell Research, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.
Chen Y; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Center for Stem Cell Research, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, HKUST Shenzhen Research Institute; Shenzhen-Hong Kong Institute of Brain Science, 518057, Shenzhen, Guangdong, China.; The Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science, 518055, Shenzhen, Guangdong, China.
Fu AKY; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Center for Stem Cell Research, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, HKUST Shenzhen Research Institute; Shenzhen-Hong Kong Institute of Brain Science, 518057, Shenzhen, Guangdong, China.
Ip NY; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Center for Stem Cell Research, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China. .; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China. .; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, HKUST Shenzhen Research Institute; Shenzhen-Hong Kong Institute of Brain Science, 518057, Shenzhen, Guangdong, China. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2021 Feb 12; Vol. 4 (1), pp. 195. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: CRISPR-Cas Systems*
Clustered Regularly Interspaced Short Palindromic Repeats*
DNA Copy Number Variations*
Gene Dosage*
Gene Editing*
CRISPR-Associated Protein 9/*genetics
Induced Pluripotent Stem Cells/*metabolism
Neurons/*metabolism
Amyloid beta-Peptides/metabolism ; Amyloid beta-Protein Precursor/genetics ; Amyloid beta-Protein Precursor/metabolism ; Apoptosis ; CRISPR-Associated Protein 9/metabolism ; Cell Line ; Gene Expression Regulation ; Humans ; Induced Pluripotent Stem Cells/pathology ; Neurogenesis ; Neurons/pathology ; Phosphorylation ; Proof of Concept Study ; tau Proteins/metabolism

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Skocz do pozycji: 14.

Tytuł:: Origin and Fates of TERT Gene Copies in Polyploid Plants.
Autorzy:: Fajkus P; Institute of Biophysics of the Czech Academy of Sciences, Královopolská 135, CZ-61265 Brno, Czech Republic.
Peška V; Institute of Biophysics of the Czech Academy of Sciences, Královopolská 135, CZ-61265 Brno, Czech Republic.
Fajkus J; Institute of Biophysics of the Czech Academy of Sciences, Královopolská 135, CZ-61265 Brno, Czech Republic.; Laboratory of Functional Genomics and Proteomics, NCBR, Faculty of Science, Masaryk University, Kotlářská 2, CZ-61137 Brno, Czech Republic.; Mendel Centre for Plant Genomics and Proteomics, CEITEC, Masaryk University, Kamenice 5, CZ-62500 Brno, Czech Republic.
Sýkorová E; Institute of Biophysics of the Czech Academy of Sciences, Královopolská 135, CZ-61265 Brno, Czech Republic.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Feb 11; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 11.
Typ publikacji:: Journal Article
MeSH Terms:: Arabidopsis*/enzymology
Arabidopsis*/genetics
Arabidopsis Proteins*/genetics
Arabidopsis Proteins*/metabolism
Gene Dosage*
Polyploidy*
Telomerase*/genetics
Telomerase*/metabolism
Nicotiana*/enzymology
Nicotiana*/genetics

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na półce

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Skocz do pozycji: 15.

Tytuł:: Diverse Evolution in 111 Plant Genomes Reveals Purifying and Dosage Balancing Selection Models for F-Box Genes.
Autorzy:: Hua Z; Interdisciplinary Program in Molecular and Cellular Biology, Department of Environmental and Plant Biology, Ohio University, Athens, OH 45701, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Jan 16; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 16.
Typ publikacji:: Journal Article
MeSH Terms:: Evolution, Molecular*
Gene Dosage*
Genome, Plant*
Selection, Genetic*
F-Box Proteins/*genetics
Plant Proteins/*genetics
Models, Genetic

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Skocz do pozycji: 16.

Tytuł:: Reference standards for accurate validation and optimization of assays that determine integrated lentiviral vector copy number in transduced cells.
Autorzy:: Paugh BS; Lentigen, a Miltenyi Biotec Company, Gaithersburg, MD, USA.
Baranyi L; Lentigen, a Miltenyi Biotec Company, Gaithersburg, MD, USA.
Roy A; Lentigen, a Miltenyi Biotec Company, Gaithersburg, MD, USA.
He HJ; National Institute of Standards and Technology, Gaithersburg, MD, USA.
Harris L; National Institute of Standards and Technology, Gaithersburg, MD, USA.
Cole KD; National Institute of Standards and Technology, Gaithersburg, MD, USA.
Artlip M; Lentigen, a Miltenyi Biotec Company, Gaithersburg, MD, USA.
Raimund C; Lentigen, a Miltenyi Biotec Company, Gaithersburg, MD, USA.
Langan PS; Lentigen, a Miltenyi Biotec Company, Gaithersburg, MD, USA.
Jana S; Lentigen, a Miltenyi Biotec Company, Gaithersburg, MD, USA.
Orentas RJ; Lentigen, a Miltenyi Biotec Company, Gaithersburg, MD, USA.
Lin-Gibson S; National Institute of Standards and Technology, Gaithersburg, MD, USA. .
Krueger W; Lentigen, a Miltenyi Biotec Company, Gaithersburg, MD, USA. .
Dropulić B; Lentigen, a Miltenyi Biotec Company, Gaithersburg, MD, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jan 11; Vol. 11 (1), pp. 389. Date of Electronic Publication: 2021 Jan 11.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Dosage*
Transduction, Genetic*/methods
Transduction, Genetic*/standards
Lentivirus/*genetics
Calibration/standards ; Gene Transfer Techniques/standards ; Genetic Vectors/genetics ; Humans ; Jurkat Cells ; Mutagenesis, Insertional/genetics ; Reference Standards ; Reproducibility of Results ; Transfection/methods ; Transfection/standards ; Validation Studies as Topic ; Virus Integration/genetics

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Skocz do pozycji: 17.

Tytuł:: Chlamydia trachomatis intra-bacterial and total plasmid copy number in clinical urogenital samples.
Autorzy:: Dirks JAMC; Department of Medical Microbiology, Maastricht University Medical Center, Care and Public Health Research Institute (Caphri), Maastricht, The Netherlands. .; Department of Sexual Health, Infectious Diseases and Environmental Health, Public Health Service South Limburg, Geleen, The Netherlands. .
Janssen K; Department of Medical Microbiology, Maastricht University Medical Center, Care and Public Health Research Institute (Caphri), Maastricht, The Netherlands.; Department of Sexual Health, Infectious Diseases and Environmental Health, Public Health Service South Limburg, Geleen, The Netherlands.
Hoebe CJPA; Department of Medical Microbiology, Maastricht University Medical Center, Care and Public Health Research Institute (Caphri), Maastricht, The Netherlands.; Department of Sexual Health, Infectious Diseases and Environmental Health, Public Health Service South Limburg, Geleen, The Netherlands.
Geelen THB; Department of Medical Microbiology, Maastricht University Medical Center, Care and Public Health Research Institute (Caphri), Maastricht, The Netherlands.
Lucchesi M; Department of Medical Microbiology, Maastricht University Medical Center, Care and Public Health Research Institute (Caphri), Maastricht, The Netherlands.
Dukers-Muijrers NHTM; Department of Medical Microbiology, Maastricht University Medical Center, Care and Public Health Research Institute (Caphri), Maastricht, The Netherlands.; Department of Sexual Health, Infectious Diseases and Environmental Health, Public Health Service South Limburg, Geleen, The Netherlands.
Wolffs PFG; Department of Medical Microbiology, Maastricht University Medical Center, Care and Public Health Research Institute (Caphri), Maastricht, The Netherlands.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jan 08; Vol. 11 (1), pp. 259. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Dosage*
Chlamydia trachomatis/*genetics
Clinical Laboratory Techniques/*methods
Female Urogenital Diseases/*microbiology
Male Urogenital Diseases/*microbiology
Trachoma/*microbiology
Chromosomes ; Female ; Female Urogenital Diseases/diagnosis ; Humans ; Male ; Male Urogenital Diseases/diagnosis ; Plasmids/urine ; Trachoma/diagnosis ; Urine/microbiology ; Vagina/microbiology ; Young Adult

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Skocz do pozycji: 18.

Tytuł:: Actionable and incidental neuroradiological findings in twins with neurodevelopmental disorders.
Autorzy:: Myers L; Center of Neurodevelopmental Disorders (KIND), Division of Neuropsychiatry, Centre for Psychiatry Research, Department of Women's and Children's Health, Karolinska Institutet and Stockholm Health Care Services, Region Stockholm, Gävlegatan 22B, 113 30, Stockholm, Sweden. .; Department of Nursing, Gustavus Adolphus College, 800 College Avenue West, St. Peter, MN, USA. .
Ho ML; Department of Radiology, Nationwide Children's Hospital, 700 Children's Drive-ED4, Columbus, OH, USA.
Cauvet E; Center of Neurodevelopmental Disorders (KIND), Division of Neuropsychiatry, Centre for Psychiatry Research, Department of Women's and Children's Health, Karolinska Institutet and Stockholm Health Care Services, Region Stockholm, Gävlegatan 22B, 113 30, Stockholm, Sweden.
Lundin K; Center of Neurodevelopmental Disorders (KIND), Division of Neuropsychiatry, Centre for Psychiatry Research, Department of Women's and Children's Health, Karolinska Institutet and Stockholm Health Care Services, Region Stockholm, Gävlegatan 22B, 113 30, Stockholm, Sweden.
Carlsson T; Center of Neurodevelopmental Disorders (KIND), Division of Neuropsychiatry, Centre for Psychiatry Research, Department of Women's and Children's Health, Karolinska Institutet and Stockholm Health Care Services, Region Stockholm, Gävlegatan 22B, 113 30, Stockholm, Sweden.; PRIMA Child and Adult Psychiatry, Götgatan 71, 116 21, Stockholm, Sweden.
Kuja-Halkola R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Nobels Väg 12A, Stockholm, Sweden.
Tammimies K; Center of Neurodevelopmental Disorders (KIND), Division of Neuropsychiatry, Centre for Psychiatry Research, Department of Women's and Children's Health, Karolinska Institutet and Stockholm Health Care Services, Region Stockholm, Gävlegatan 22B, 113 30, Stockholm, Sweden.; Astrid Lindgren Children's' Hospital, Karolinska University Hospital, Region Stockholm, Bioclinicum J9:30, Akademiska Straket 1, Solna, Sweden.
Bölte S; Center of Neurodevelopmental Disorders (KIND), Division of Neuropsychiatry, Centre for Psychiatry Research, Department of Women's and Children's Health, Karolinska Institutet and Stockholm Health Care Services, Region Stockholm, Gävlegatan 22B, 113 30, Stockholm, Sweden.; Curtin Autism Research Group, School of Occupational Therapy, Social Work and Speech Pathology, Curtin University, Kent Street, Bentley, Perth, WA, 6845, Australia.; Child and Adolescent Psychiatry, Stockholm Health Care Services, Region Stockholm, Gävlegatan 22B, 113 30, Stockholm, Sweden.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Dec 29; Vol. 10 (1), pp. 22417. Date of Electronic Publication: 2020 Dec 29.
Typ publikacji:: Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't; Twin Study
MeSH Terms:: Attention Deficit and Disruptive Behavior Disorders*/diagnostic imaging
Attention Deficit and Disruptive Behavior Disorders*/epidemiology
Attention Deficit and Disruptive Behavior Disorders*/genetics
Autism Spectrum Disorder*/diagnostic imaging
Autism Spectrum Disorder*/epidemiology
Autism Spectrum Disorder*/genetics
Gene Dosage*
Magnetic Resonance Imaging*
Polymorphism, Genetic*
Sex Characteristics*
Twins, Dizygotic*
Twins, Monozygotic*
Adolescent ; Adult ; Child ; Female ; Humans ; Incidence ; Male ; Severity of Illness Index

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Skocz do pozycji: 19.

Tytuł:: The role of gene dosage in budding yeast centrosome scaling and spontaneous diploidization.
Autorzy:: Chen J; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America.
Xiong Z; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America.
Miller DE; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America.
Yu Z; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America.
McCroskey S; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America.
Bradford WD; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America.
Cavanaugh AM; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America.
Jaspersen SL; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America.; Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States of America.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2020 Dec 17; Vol. 16 (12), pp. e1008911. Date of Electronic Publication: 2020 Dec 17 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Diploidy*
Gene Dosage*
Centromere/*genetics
Chromosomes, Fungal/*genetics
Centromere/metabolism ; Chromosomes, Fungal/metabolism ; Saccharomyces cerevisiae ; Spindle Pole Bodies/genetics ; Spindle Pole Bodies/metabolism

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na półce

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Skocz do pozycji: 20.

Tytuł:: An effective combination of codon optimization, gene dosage, and process optimization for high-level production of fibrinolytic enzyme in Komagataella phaffii (Pichia pastoris).
Autorzy:: Che Z; State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Microorganism and Enyme Research Center of Engineering Technology, College of Life Science and Technology, Guangxi University, Nanning, 530004, China.
Cao X; College of Agriculture and Forestry Science, Linyi University, Linyi, 276000, China.
Chen G; State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Microorganism and Enyme Research Center of Engineering Technology, College of Life Science and Technology, Guangxi University, Nanning, 530004, China.
Liang Z; State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Microorganism and Enyme Research Center of Engineering Technology, College of Life Science and Technology, Guangxi University, Nanning, 530004, China. .; Pokaż więcej
Źródło:: BMC biotechnology [BMC Biotechnol] 2020 Dec 04; Vol. 20 (1), pp. 63. Date of Electronic Publication: 2020 Dec 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Dosage*
Codon/*metabolism
Saccharomycetales/*enzymology
Saccharomycetales/*genetics
Bacillus subtilis ; Bioreactors ; Fermentation ; Fibrinolytic Agents ; Fungal Proteins/genetics ; Fungal Proteins/metabolism ; Gene Expression Regulation, Fungal ; Hydrogen-Ion Concentration ; Industrial Microbiology ; Kinetics ; Recombinant Proteins/genetics ; Temperature ; Thrombosis/prevention & control
SCR Organism:: Komagataella pastoris; Komagataella phaffii

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