Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""glioblastoma"" wg kryterium: Temat


Tytuł :
Combining MGMT promoter pyrosequencing and protein expression to optimize prognosis stratification in glioblastoma.
Autorzy :
Li M; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Dong G; Department of Pathology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhang W; Department of Pathology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Ren X; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Jiang H; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yang C; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhao X; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhu Q; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Li M; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Chen H; Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yu K; Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Cui Y; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Song L; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Center of Brain Tumor, Institute for Brain Disorders and Beijing Key Laboratory of Brain Tumor, Beijing, China.; Department of Neurosurgery, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Pokaż więcej
Źródło :
Cancer science [Cancer Sci] 2021 Sep; Vol. 112 (9), pp. 3699-3710. Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms/*genetics
Brain Neoplasms/*metabolism
DNA Modification Methylases/*genetics
DNA Modification Methylases/*metabolism
DNA Repair Enzymes/*genetics
DNA Repair Enzymes/*metabolism
Glioblastoma/*genetics
Glioblastoma/*metabolism
Promoter Regions, Genetic/*genetics
Tumor Suppressor Proteins/*genetics
Tumor Suppressor Proteins/*metabolism
Adolescent ; Adult ; Aged ; Brain Neoplasms/mortality ; Brain Neoplasms/pathology ; CpG Islands/genetics ; DNA Methylation ; Female ; Follow-Up Studies ; Glioblastoma/mortality ; Glioblastoma/pathology ; High-Throughput Nucleotide Sequencing ; Humans ; Immunohistochemistry/methods ; Male ; Middle Aged ; Prognosis ; Progression-Free Survival ; Retrospective Studies ; Survival Rate ; Young Adult
Czasopismo naukowe
Tytuł :
A Super-selective Wada Test Successfully Detected an Artery That Supplied Broca's Area in a Case of Left Frontal Lobe Glioblastoma: Technical Case Report.
Autorzy :
Yamashita S; Department of Neurosurgery, Graduate School of Medicine, Tohoku University.
Saito R; Department of Neurosurgery, Graduate School of Medicine, Tohoku University.; Department of Neurosurgical Engineering and Translational Neuroscience, Tohoku University Graduate School of Medicine.
Osawa SI; Department of Neurosurgery, Graduate School of Medicine, Tohoku University.
Niizuma K; Department of Neurosurgery, Graduate School of Medicine, Tohoku University.; Department of Neurosurgical Engineering and Translational Neuroscience, Tohoku University Graduate School of Medicine.; Department of Neurosurgical Engineering and Translational Neuroscience, Graduate School of Biomedical Engineering, Tohoku University.
Ukishiro K; Department of Epileptology, Graduate School of Medicine, Tohoku University.
Kanamori M; Department of Neurosurgery, Graduate School of Medicine, Tohoku University.
Kakinuma K; Department of Behavioral Neurology and Cognitive Neuroscience, Graduate School of Medicine, Tohoku University.
Suzuki K; Department of Behavioral Neurology and Cognitive Neuroscience, Graduate School of Medicine, Tohoku University.
Tominaga T; Department of Neurosurgery, Graduate School of Medicine, Tohoku University.
Pokaż więcej
Źródło :
Neurologia medico-chirurgica [Neurol Med Chir (Tokyo)] 2021 Nov 15; Vol. 61 (11), pp. 661-666. Date of Electronic Publication: 2021 Aug 26.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/surgery
Glioblastoma*/diagnostic imaging
Glioblastoma*/surgery
Adult ; Brain Mapping ; Broca Area/diagnostic imaging ; Frontal Lobe/diagnostic imaging ; Frontal Lobe/surgery ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Cerebral Artery ; Wakefulness
Czasopismo naukowe
Tytuł :
Perfusion parameters derived from MRI for preoperative prediction of IDH mutation and MGMT promoter methylation status in glioblastomas.
Autorzy :
Lu J; Department of Radiology, The Affiliated Tumor Hospital of Zhengzhou University & Henan Cancer Hospital, China.
Li X; Department of Radiology, The Affiliated Tumor Hospital of Zhengzhou University & Henan Cancer Hospital, China.
Li H; Department of Radiology, The Affiliated Tumor Hospital of Zhengzhou University & Henan Cancer Hospital, China. Electronic address: .
Pokaż więcej
Źródło :
Magnetic resonance imaging [Magn Reson Imaging] 2021 Nov; Vol. 83, pp. 189-195. Date of Electronic Publication: 2021 Sep 08.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/genetics
DNA Modification Methylases*/genetics
DNA Repair Enzymes*/genetics
Glioblastoma*/diagnostic imaging
Glioblastoma*/genetics
Tumor Suppressor Proteins*/genetics
Isocitrate Dehydrogenase/*genetics
Diffusion Magnetic Resonance Imaging ; Humans ; Magnetic Resonance Imaging ; Methylation ; Mutation ; Perfusion ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Correlation between dynamic susceptibility contrast perfusion MRI and genomic alterations in glioblastoma.
Autorzy :
Ozturk K; Department of Radiology, University of Minnesota Health, B-226 Mayo Memorial Building, MMC 292, 420 Delaware Street S.E., Minneapolis, MN, 55455, USA.
Soylu E; Department of Radiology, University of Minnesota Health, B-226 Mayo Memorial Building, MMC 292, 420 Delaware Street S.E., Minneapolis, MN, 55455, USA.
Cayci Z; Department of Radiology, University of Minnesota Health, B-226 Mayo Memorial Building, MMC 292, 420 Delaware Street S.E., Minneapolis, MN, 55455, USA. .
Pokaż więcej
Źródło :
Neuroradiology [Neuroradiology] 2021 Nov; Vol. 63 (11), pp. 1801-1810. Date of Electronic Publication: 2021 Mar 18.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/genetics
Glioblastoma*/diagnostic imaging
Glioblastoma*/genetics
Adult ; Aged ; Aged, 80 and over ; Female ; Genomics ; Humans ; Isocitrate Dehydrogenase/genetics ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Mutation ; Perfusion ; Retrospective Studies ; Young Adult
Czasopismo naukowe
Tytuł :
Long noncoding RNA just proximal to X-inactive specific transcript facilitates aerobic glycolysis and temozolomide chemoresistance by promoting stability of PDK1 mRNA in an m6A-dependent manner in glioblastoma multiforme cells.
Autorzy :
Li XD; Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wang MJ; Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zheng JL; Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wu YH; Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wang X; Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jiang XB; Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Pokaż więcej
Źródło :
Cancer science [Cancer Sci] 2021 Nov; Vol. 112 (11), pp. 4543-4552. Date of Electronic Publication: 2021 Aug 30.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Alkylating/*pharmacology
Brain Neoplasms/*metabolism
Glioblastoma/*metabolism
Pyruvate Dehydrogenase Acetyl-Transferring Kinase/*metabolism
RNA, Long Noncoding/*metabolism
Temozolomide/*pharmacology
Adenosine/analogs & derivatives ; Adenosine/metabolism ; Aerobiosis ; Alpha-Ketoglutarate-Dependent Dioxygenase FTO/metabolism ; Brain Neoplasms/drug therapy ; Brain Neoplasms/mortality ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Demethylation ; Disease Progression ; Drug Resistance, Neoplasm ; Glioblastoma/drug therapy ; Glioblastoma/mortality ; Glioblastoma/pathology ; Glycolysis ; Humans ; Neoplasm Proteins/metabolism ; Prognosis ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
Glioblastoma with primitive neuronal component: An immunohistochemical study and review of literature.
Autorzy :
Poyuran R; Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum 695011, Kerala, India. Electronic address: .
Chandrasekharan K; Department of Imaging Sciences and Intervention Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum 695011, Kerala, India. Electronic address: .
Easwer HV; Department of Neurosurgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum 695011, Kerala, India. Electronic address: .
Narasimhaiah D; Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum 695011, Kerala, India. Electronic address: .
Pokaż więcej
Źródło :
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia [J Clin Neurosci] 2021 Nov; Vol. 93, pp. 130-136. Date of Electronic Publication: 2021 Sep 20.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/genetics
Glioblastoma*/diagnostic imaging
Glioblastoma*/genetics
Adult ; Child ; Female ; Humans ; Infant ; Male ; Middle Aged ; Mutation
Czasopismo naukowe
Tytuł :
Chemopreventive effect of spirulina microalgae on an animal model of glioblastoma via down-regulation of PI3K/AKT/mTOR and up-regulation of miR-34a/miR-125B expression.
Autorzy :
Arab S; Nervous System Stem Cells Research Center, Semnan University of Medical Sciences, Semnan, Iran.; Department of Tissue Engineering and Applied Cell Sciences, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Ghasemi S; Student research committee, Semnan University of Medical Sciences, Semnan, Iran.
Ghanbari A; Research center of physiology, Semnan University of Medical Sciences, Semnan, Iran.
Bahraminasab M; Nervous System Stem Cells Research Center, Semnan University of Medical Sciences, Semnan, Iran.; Department of Tissue Engineering and Applied Cell Sciences, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Satari A; Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Mousavi M; Department of Anatomy, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Dehcheshme HG; Student research committee, Semnan University of Medical Sciences, Semnan, Iran.
Asgharzade S; Student research committee, Semnan University of Medical Sciences, Semnan, Iran.
Pokaż więcej
Źródło :
Phytotherapy research : PTR [Phytother Res] 2021 Nov; Vol. 35 (11), pp. 6452-6461. Date of Electronic Publication: 2021 Oct 04.
Typ publikacji :
Journal Article
MeSH Terms :
Glioblastoma*/drug therapy
Glioblastoma*/genetics
MicroRNAs*/genetics
Microalgae*
Spirulina*
Animals ; Apoptosis ; Cell Proliferation ; Disease Models, Animal ; Down-Regulation ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł :
Patterns of glioblastoma treatment and survival over a 16-years period: pooled data from the German Cancer Registries.
Autorzy :
Efremov L; Institute for Medical Epidemiology, Biometrics and Informatics (IMEBI), Interdisciplinary Center for Health Sciences, Medical School of the Martin-Luther-University Halle-Wittenberg, Magdeburger Str. 8, 06112, Halle (Saale), Germany.; Department of Radiation Oncology, Martin-Luther-University, Halle (Saale), Germany.
Abera SF; Department of Radiation Oncology, Martin-Luther-University, Halle (Saale), Germany.
Bedir A; Department of Radiation Oncology, Martin-Luther-University, Halle (Saale), Germany.
Vordermark D; Department of Radiation Oncology, Martin-Luther-University, Halle (Saale), Germany.
Medenwald D; Institute for Medical Epidemiology, Biometrics and Informatics (IMEBI), Interdisciplinary Center for Health Sciences, Medical School of the Martin-Luther-University Halle-Wittenberg, Magdeburger Str. 8, 06112, Halle (Saale), Germany. .; Department of Radiation Oncology, Martin-Luther-University, Halle (Saale), Germany. .
Pokaż więcej
Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2021 Nov; Vol. 147 (11), pp. 3381-3390. Date of Electronic Publication: 2021 Mar 20.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms/*mortality
Brain Neoplasms/*therapy
Glioblastoma/*mortality
Glioblastoma/*therapy
Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Antineoplastic Agents, Alkylating/administration & dosage ; Brain Neoplasms/drug therapy ; Female ; Germany/epidemiology ; Glioblastoma/drug therapy ; Humans ; Male ; Middle Aged ; Proportional Hazards Models ; Registries ; Survival Rate ; Temozolomide/administration & dosage ; Young Adult
Czasopismo naukowe
Tytuł :
Glioblastoma with deep supratentorial extension is associated with a worse overall survival.
Autorzy :
Barsouk A; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Baldassari MP; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Khanna O; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Andrews CE; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Ye DY; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Velagapudi L; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Al Saiegh F; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Hafazalla K; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Cunningham E; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Patel H; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Malkani K; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Fitchett EM; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Farrell CJ; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Judy KD; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA. Electronic address: .
Pokaż więcej
Źródło :
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia [J Clin Neurosci] 2021 Nov; Vol. 93, pp. 82-87. Date of Electronic Publication: 2021 Sep 15.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/surgery
Glioblastoma*/diagnostic imaging
Glioblastoma*/surgery
Supratentorial Neoplasms*/diagnostic imaging
Supratentorial Neoplasms*/surgery
Humans ; Prognosis ; Progression-Free Survival ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Versatile metal-phenolic network nanoparticles for multitargeted combination therapy and magnetic resonance tracing in glioblastoma.
Autorzy :
Zhang Y; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Xi K; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Fu X; Key Laboratory of Colloid and Interface Chemistry of the Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong, 250100, China.
Sun H; Key Laboratory of Colloid and Interface Chemistry of the Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong, 250100, China.
Wang H; Radiology Department, Qilu Hospital of Shandong University, Jinan, Shandong, 250012, China.
Yu D; Radiology Department, Qilu Hospital of Shandong University, Jinan, Shandong, 250012, China.
Li Z; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Ma Y; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Liu X; Department of Pediatrics, Qilu Hospital, Shandong University, Jinan, Shandong, 250012, China.
Huang B; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Wang J; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Li G; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Cui J; Key Laboratory of Colloid and Interface Chemistry of the Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong, 250100, China.
Li X; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Ni S; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China. Electronic address: .
Pokaż więcej
Źródło :
Biomaterials [Biomaterials] 2021 Nov; Vol. 278, pp. 121163. Date of Electronic Publication: 2021 Sep 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glioblastoma*/diagnostic imaging
Glioblastoma*/drug therapy
Metal Nanoparticles*
Nanoparticles*
Apoptosis ; Cell Line, Tumor ; Combined Modality Therapy ; Humans ; Magnetic Resonance Spectroscopy
Czasopismo naukowe
Tytuł :
Discovery of pyrrole derivatives for the treatment of glioblastoma and chronic myeloid leukemia.
Autorzy :
Puxeddu M; Laboratory Affiliated with the Institute Pasteur Italy - Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
Shen H; Department of Urology, Capital Medical University Beijing Friendship Hospital, Beijing, 100050, China.
Bai R; Molecular Pharmacology Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, Frederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, United States.
Coluccia A; Laboratory Affiliated with the Institute Pasteur Italy - Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
Bufano M; Laboratory Affiliated with the Institute Pasteur Italy - Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
Nalli M; Laboratory Affiliated with the Institute Pasteur Italy - Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
Sebastiani J; Laboratory Affiliated with the Institute Pasteur Italy - Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
Brancaccio D; Department of Pharmacy, University of Naples'Federico II', Via Domenico Montesano 49, 80131, Naples, Italy.
Da Pozzo E; Department of Pharmacy, University of Pisa, Via Bonanno Pisano 6, I-56126, Pisa, Italy.
Tremolanti C; Department of Pharmacy, University of Pisa, Via Bonanno Pisano 6, I-56126, Pisa, Italy.
Martini C; Department of Pharmacy, University of Pisa, Via Bonanno Pisano 6, I-56126, Pisa, Italy.
Orlando V; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
Biagioni S; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
Sinicropi MS; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, I-87036, Rende, Cosenza, Italy.
Ceramella J; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, I-87036, Rende, Cosenza, Italy.
Iacopetta D; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, I-87036, Rende, Cosenza, Italy.
Coluccia AML; Department of Biological and Environmental Sciences and Technologies, University of Salento, I-73100, Lecce, Italy.
Hamel E; Molecular Pharmacology Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, Frederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, United States.
Liu T; Department of Biological and Environmental Sciences and Technologies, University of Salento, I-73100, Lecce, Italy; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 365 South Xiangyang Road, Shanghai, 200031, China. Electronic address: .
Silvestri R; Laboratory Affiliated with the Institute Pasteur Italy - Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy. Electronic address: .
La Regina G; Laboratory Affiliated with the Institute Pasteur Italy - Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy. Electronic address: .
Pokaż więcej
Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Oct 05; Vol. 221, pp. 113532. Date of Electronic Publication: 2021 May 05.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Discovery*
Antineoplastic Agents/*pharmacology
Glioblastoma/*drug therapy
Heterocyclic Compounds/*pharmacology
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*drug therapy
Methane/*pharmacology
Tubulin Modulators/*pharmacology
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Female ; Glioblastoma/metabolism ; Glioblastoma/pathology ; Heterocyclic Compounds/chemical synthesis ; Heterocyclic Compounds/chemistry ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/metabolism ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology ; Methane/analogs & derivatives ; Methane/chemistry ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Molecular Structure ; Neoplasms, Experimental/drug therapy ; Neoplasms, Experimental/metabolism ; Neoplasms, Experimental/pathology ; Polymerization/drug effects ; Structure-Activity Relationship ; Tubulin/metabolism ; Tubulin Modulators/chemical synthesis ; Tubulin Modulators/chemistry ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Liquid Biopsy in Glioblastoma Management: From Current Research to Future Perspectives.
Autorzy :
Gatto L; Department of Medical Oncology, Azienda Unità Sanitaria Locale (USL) of Bologna, Bologna, Italy.
Franceschi E; Department of Medical Oncology, Azienda Unità Sanitaria Locale (USL) of Bologna, Bologna, Italy.
Di Nunno V; Department of Medical Oncology, Azienda Unità Sanitaria Locale (USL) of Bologna, Bologna, Italy.
Tosoni A; Department of Medical Oncology, Azienda Unità Sanitaria Locale (USL) of Bologna, Bologna, Italy.
Lodi R; Istituto delle Scienze Neurologiche di Bologna, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Bologna, Italy.
Brandes AA; Department of Medical Oncology, Azienda Unità Sanitaria Locale (USL) of Bologna, Bologna, Italy.
Pokaż więcej
Źródło :
The oncologist [Oncologist] 2021 Oct; Vol. 26 (10), pp. 865-878. Date of Electronic Publication: 2021 Jun 23.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Brain Neoplasms*/diagnosis
Brain Neoplasms*/genetics
Brain Neoplasms*/therapy
Glioblastoma*/diagnosis
Glioblastoma*/genetics
Glioblastoma*/therapy
MicroRNAs*
Biomarkers, Tumor/genetics ; Humans ; Liquid Biopsy ; Prognosis
Czasopismo naukowe
Tytuł :
BET inhibitors repress expression of interferon-stimulated genes and synergize with HDAC inhibitors in glioblastoma.
Autorzy :
Gusyatiner O; Neuroscience Research Centre, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Service of Neurosurgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Lausanne, Switzerland.
Bady P; Neuroscience Research Centre, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Service of Neurosurgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Bioinformatics Core Facility, SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Lausanne, Switzerland.
Pham MDT; Neuroscience Research Centre, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Lei Y; Neuroscience Research Centre, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Park J; Neuroscience Research Centre, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Daniel RT; Service of Neurosurgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Delorenzi M; Bioinformatics Core Facility, SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Department of Oncology, University of Lausanne, Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Lausanne, Switzerland.
Hegi ME; Service of Neurosurgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Lausanne, Switzerland.
Pokaż więcej
Źródło :
Neuro-oncology [Neuro Oncol] 2021 Oct 01; Vol. 23 (10), pp. 1680-1692.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glioblastoma*/drug therapy
Glioblastoma*/genetics
Histone Deacetylase Inhibitors*/pharmacology
Humans ; Interferons ; Nuclear Proteins
Czasopismo naukowe
Tytuł :
The anesthetist's choice of inhalational vs. intravenous anesthetics has no impact on survival of glioblastoma patients.
Autorzy :
Schmoch T; Department of Anesthesiology and Intensive Care Medicine, University Hospital Essen, Hufelandstraße 55, 45147, Essen, Germany. .; Department of Anesthesiology, University Hospital Heidelberg, Heidelberg, Germany. .
Jungk C; Division of Neurosurgical Research, Department of Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany.
Bruckner T; Institute of Medical Biometry and Informatics (IMBI), University of Heidelberg, Heidelberg, Germany.
Haag S; Department of Anesthesiology, University Hospital Heidelberg, Heidelberg, Germany.
Zweckberger K; Division of Neurosurgical Research, Department of Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany.
von Deimling A; Department of Neuropathology, University Hospital Heidelberg and Clinical Cooperation Unit (CCU) Neuropathology, DKFZ, Heidelberg, Germany.
Brenner T; Department of Anesthesiology and Intensive Care Medicine, University Hospital Essen, Hufelandstraße 55, 45147, Essen, Germany.
Unterberg A; Division of Neurosurgical Research, Department of Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany.
Weigand MA; Department of Anesthesiology, University Hospital Heidelberg, Heidelberg, Germany.
Uhle F; Department of Anesthesiology, University Hospital Heidelberg, Heidelberg, Germany.
Herold-Mende C; Division of Neurosurgical Research, Department of Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany.
Pokaż więcej
Źródło :
Neurosurgical review [Neurosurg Rev] 2021 Oct; Vol. 44 (5), pp. 2707-2715. Date of Electronic Publication: 2020 Dec 22.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms*/drug therapy
Brain Neoplasms*/surgery
Glioblastoma*/drug therapy
Glioblastoma*/surgery
Anesthetics, Intravenous ; Anesthetists ; DNA Modification Methylases ; DNA Repair Enzymes ; Humans ; Prognosis ; Retrospective Studies ; Wakefulness
Czasopismo naukowe
Tytuł :
Construction of IL-13 Receptor α2-Targeting Resveratrol Nanoparticles against Glioblastoma Cells: Therapeutic Efficacy and Molecular Effects.
Autorzy :
Lin XM; Research Center, South China University of Technology (SCUT) School of Medicine, Guangzhou 510006, China.
Shi XX; Institute of Life Sciences, South China University of Technology (SCUT) School of Medicine, Guangzhou 510006, China.
Xiong L; Research Center, South China University of Technology (SCUT) School of Medicine, Guangzhou 510006, China.
Nie JH; Research Center, South China University of Technology (SCUT) School of Medicine, Guangzhou 510006, China.
Ye HS; Research Center, South China University of Technology (SCUT) School of Medicine, Guangzhou 510006, China.
Du JZ; Institute of Life Sciences, South China University of Technology (SCUT) School of Medicine, Guangzhou 510006, China.
Liu J; Research Center, South China University of Technology (SCUT) School of Medicine, Guangzhou 510006, China.; Liaoning Laboratory of Cancer Genetics and Epigenetics, Dalian Medical University, Dalian 610044, China.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 30; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 30.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms/*drug therapy
Brain Neoplasms/*metabolism
Drug Carriers/*chemistry
Glioblastoma/*drug therapy
Glioblastoma/*metabolism
Interleukin-13 Receptor alpha2 Subunit/*antagonists & inhibitors
Interleukin-13 Receptor alpha2 Subunit/*metabolism
Nanoparticles/*chemistry
Resveratrol/*administration & dosage
Animals ; Apoptosis/drug effects ; Brain Neoplasms/pathology ; Capsules ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Liberation ; Glioblastoma/pathology ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Rats ; Treatment Outcome ; Tumor Burden/drug effects ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Gene clusters based on OLIG2 and CD276 could distinguish molecular profiling in glioblastoma.
Autorzy :
Fu M; Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.; Institute of Neurosurgery, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Brain Function Restoration and Neural Regeneration, Shanghai, China.
Zhang J; Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.; Institute of Neurosurgery, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Brain Function Restoration and Neural Regeneration, Shanghai, China.
Li W; School of Computer Science, University of Birmingham, Edgartown, UK.
He S; School of Computer Science, University of Birmingham, Edgartown, UK.
Zhang J; Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.; Institute of Neurosurgery, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Brain Function Restoration and Neural Regeneration, Shanghai, China.
Tennant D; Institute of Metabolism and Systems Research, University of Birmingham, Edgartown, UK.
Hua W; Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China. .; Institute of Neurosurgery, Fudan University, Shanghai, China. .; Shanghai Key Laboratory of Brain Function Restoration and Neural Regeneration, Shanghai, China. .
Mao Y; Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China. .; Institute of Neurosurgery, Fudan University, Shanghai, China. .; Shanghai Key Laboratory of Brain Function Restoration and Neural Regeneration, Shanghai, China. .
Pokaż więcej
Źródło :
Journal of translational medicine [J Transl Med] 2021 Sep 26; Vol. 19 (1), pp. 404. Date of Electronic Publication: 2021 Sep 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Neoplasms*/diagnosis
Brain Neoplasms*/genetics
Glioblastoma*/diagnosis
Glioblastoma*/genetics
B7 Antigens ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Multigene Family ; Oligodendrocyte Transcription Factor 2/genetics ; Prognosis
Czasopismo naukowe
Tytuł :
MicroRNA Delivery by Graphene-Based Complexes into Glioblastoma Cells.
Autorzy :
Kutwin M; Department of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences, 02-786 Warsaw, Poland.
Sosnowska ME; Department of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences, 02-786 Warsaw, Poland.
Strojny-Cieślak B; Department of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences, 02-786 Warsaw, Poland.
Jaworski S; Department of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences, 02-786 Warsaw, Poland.
Trzaskowski M; Centre for Advanced Materials and Technologies CEZAMAT, Warsaw University of Technology, 02-822 Warsaw, Poland.
Wierzbicki M; Department of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences, 02-786 Warsaw, Poland.
Chwalibog A; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 1870 Frederiksberg, Denmark.
Sawosz E; Department of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences, 02-786 Warsaw, Poland.
Pokaż więcej
Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Sep 25; Vol. 26 (19). Date of Electronic Publication: 2021 Sep 25.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms/*therapy
Glioblastoma/*therapy
Graphite/*chemistry
MicroRNAs/*antagonists & inhibitors
RNA, Antisense/*administration & dosage
RNA, Antisense/*chemistry
Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Cell Survival ; Drug Delivery Systems ; Glioblastoma/genetics ; Glioblastoma/pathology ; Humans ; MicroRNAs/administration & dosage ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
The Presence and Potential Role of ALDH1A2 in the Glioblastoma Microenvironment.
Autorzy :
Sanders S; Department of Cancer Biology, Wake Forest School of Medicine, Winston Salem, NC 27157, USA.; Brain Tumor Center of Excellence, Wake Forest Baptist Medical Center Comprehensive Cancer Center, Winston Salem, NC 27157, USA.
Herpai DM; Department of Cancer Biology, Wake Forest School of Medicine, Winston Salem, NC 27157, USA.; Brain Tumor Center of Excellence, Wake Forest Baptist Medical Center Comprehensive Cancer Center, Winston Salem, NC 27157, USA.
Rodriguez A; Department of Neurosurgery, Jackson T. Stephens Spine and Neuroscience Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.; Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Huang Y; Department of Cancer Biology, Wake Forest School of Medicine, Winston Salem, NC 27157, USA.; Brain Tumor Center of Excellence, Wake Forest Baptist Medical Center Comprehensive Cancer Center, Winston Salem, NC 27157, USA.
Chou J; Department of Cancer Biology, Wake Forest School of Medicine, Winston Salem, NC 27157, USA.
Hsu FC; Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston Salem, NC 27157, USA.
Seals D; Biology Department, Appalachian State University, Boone, NC 28608, USA.
Mott R; Department of Pathology, Wake Forest School of Medicine, Winston Salem, NC 27157, USA.
Miller LD; Department of Cancer Biology, Wake Forest School of Medicine, Winston Salem, NC 27157, USA.
Debinski W; Department of Cancer Biology, Wake Forest School of Medicine, Winston Salem, NC 27157, USA.; Brain Tumor Center of Excellence, Wake Forest Baptist Medical Center Comprehensive Cancer Center, Winston Salem, NC 27157, USA.
Pokaż więcej
Źródło :
Cells [Cells] 2021 Sep 20; Vol. 10 (9). Date of Electronic Publication: 2021 Sep 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Aldehyde Dehydrogenase 1 Family/*metabolism
Glioblastoma/*pathology
Macrophages/*immunology
Matrix Metalloproteinase 2/*metabolism
Matrix Metalloproteinase 9/*metabolism
Retinal Dehydrogenase/*metabolism
Aldehyde Dehydrogenase 1 Family/genetics ; Aldehyde Dehydrogenase 1 Family/immunology ; Apoptosis ; Brain Neoplasms/genetics ; Brain Neoplasms/immunology ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Cell Movement ; Cell Proliferation ; Glioblastoma/genetics ; Glioblastoma/immunology ; Glioblastoma/metabolism ; Humans ; Matrix Metalloproteinase 2/genetics ; Matrix Metalloproteinase 9/genetics ; Retinal Dehydrogenase/genetics ; Retinal Dehydrogenase/immunology ; Tretinoin/metabolism ; Tumor Cells, Cultured ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
A Crowdsourced Consensus on Supratotal Resection Versus Gross Total Resection for Anatomically Distinct Primary Glioblastoma.
Autorzy :
Khalafallah AM; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Rakovec M; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Bettegowda C; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jackson CM; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Gallia GL; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Weingart JD; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Lim M; Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA.
Esquenazi Y; Vivian L. Smith Department of Neurosurgery, University of Texas Health Science Center, Houston, Texas, USA.
Zacharia BE; Department of Neurosurgery, Penn State Milton S. Hershey Medical Center, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Goldschmidt E; Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Ziu M; Inova Neuroscience and Spine Institute, University of Virginia Medical School-Inova Campus, Falls Church, Virginia, USA.
Ivan ME; Sylvester Comprehensive Cancer Center, Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.
Venteicher AS; Center for Skull Base and Pituitary Surgery, Department of Neurosurgery, University of Minnesota, Minneapolis, Minnesota, USA.
Nduom EK; Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health (NIH), Bethesda, Maryland, USA.
Mamelak AN; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Chu RM; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Yu JS; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Sheehan JP; Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia, USA.
Nahed BV; Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Carter BS; Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Berger MS; Department of Neurological Surgery, University of California, San Francisco, San Francisco, California, USA.
Sawaya R; Division of Surgery, Department of Neurosurgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Mukherjee D; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Pokaż więcej
Źródło :
Neurosurgery [Neurosurgery] 2021 Sep 15; Vol. 89 (4), pp. 712-719.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/surgery
Crowdsourcing*
Glioblastoma*/diagnostic imaging
Glioblastoma*/surgery
Consensus ; Humans ; Neurosurgical Procedures ; Prospective Studies
Czasopismo naukowe
Tytuł :
BEX1 and BEX4 Induce GBM Progression through Regulation of Actin Polymerization and Activation of YAP/TAZ Signaling.
Autorzy :
Lee S; Department of Integrated Biological Science, Pusan National University, Busan 46241, Korea.
Kang H; Department of Integrated Biological Science, Pusan National University, Busan 46241, Korea.
Shin E; Department of Integrated Biological Science, Pusan National University, Busan 46241, Korea.
Jeon J; Department of Radiation Oncology, Haeundae Paik Hospital, Inje University College of Medicine, Busan 48108, Korea.
Youn H; Department of Integrative Bioscience and Biotechnology, Sejong University, Seoul 05006, Korea.
Youn B; Department of Integrated Biological Science, Pusan National University, Busan 46241, Korea.; Department of Biological Sciences, Pusan National University, Busan 46241, Korea.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 11; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 11.
Typ publikacji :
Journal Article
MeSH Terms :
Signal Transduction*
Actins/*metabolism
Adaptor Proteins, Signal Transducing/*metabolism
Glioblastoma/*metabolism
Microtubule-Associated Proteins/*metabolism
Nerve Tissue Proteins/*metabolism
Oncogene Proteins/*metabolism
Transcription Factors/*metabolism
Actins/genetics ; Adaptor Proteins, Signal Transducing/genetics ; Animals ; Cell Line, Tumor ; Glioblastoma/genetics ; Glioblastoma/pathology ; Heterografts ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Microtubule-Associated Proteins/genetics ; Neoplasm Transplantation ; Nerve Tissue Proteins/genetics ; Oncogene Proteins/genetics ; Transcription Factors/genetics
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies