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Tytuł:
Glutathione peroxidase 1 and 2 during preimplantation period of pregnancy in mouse.
Autorzy:
Krehelova A
Kovarikova V
Fabian D
Solar P
Curgali K
Neratzakis I
Hodorova I
Mihalik J
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Źródło:
Bratislavske lekarske listy [Bratisl Lek Listy] 2024; Vol. 125 (1), pp. 64-74.
Typ publikacji:
Journal Article
MeSH Terms:
Glutathione Peroxidase GPX1*
Embryo Implantation*
Pregnancy ; Female ; Animals ; Mice ; Glutathione Peroxidase/metabolism ; Antioxidants
Czasopismo naukowe
Tytuł:
Polyalanine polymorphism in the signal peptide of Glutathione peroxidase 1 ( GPX1 ) gene & its association with osteoporosis.
Autorzy:
Ahuja SG; Department of Zoology, Savitribai Phule Pune University, Pune, Maharashtra, India.
Shahu A; Department of Zoology, Savitribai Phule Pune University, Pune, Maharashtra, India.
Rath S; Division of Statistical Quality Control and Operations Research, Indian Statistical Institute, Pune, Maharashtra, India.
Adkar N; SaiShree Hospital & Joint Replacement Center, Pune, Maharashtra, India.
Shouche Y; National Centre for Microbial Resource, Microbial Culture Collection, National Centre for Cell Science, Pune, Maharashtra, India.
Ghaskadbi S; Department of Zoology, Savitribai Phule Pune University, Pune, Maharashtra, India.
Ashma R; Department of Zoology, Savitribai Phule Pune University, Pune, Maharashtra, India.
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Źródło:
The Indian journal of medical research [Indian J Med Res] 2022 Oct-Nov; Vol. 156 (4&5), pp. 640-647.
Typ publikacji:
Journal Article
MeSH Terms:
Glutathione Peroxidase GPX1*
Osteoporosis*/genetics
Osteoporosis*/complications
Humans ; Protein Sorting Signals ; Antioxidants ; Vitamin D ; Glutathione Peroxidase/genetics ; Glutathione Peroxidase/metabolism ; Bone Density/genetics
Czasopismo naukowe
Tytuł:
Antioxidant Genetic Variants Modify Echocardiography Indices in Long COVID.
Autorzy:
Asanin M; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Clinic of Cardiology, Clinical Centre of Serbia, 11000 Belgrade, Serbia.
Ercegovac M; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Clinic of Neurology, Clinical Centre of Serbia, 11000 Belgrade, Serbia.
Krljanac G; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Clinic of Cardiology, Clinical Centre of Serbia, 11000 Belgrade, Serbia.
Djukic T; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Institute of Medical and Clinical Biochemistry, 11000 Belgrade, Serbia.
Coric V; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Institute of Medical and Clinical Biochemistry, 11000 Belgrade, Serbia.
Jerotic D; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Institute of Medical and Clinical Biochemistry, 11000 Belgrade, Serbia.
Pljesa-Ercegovac M; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Institute of Medical and Clinical Biochemistry, 11000 Belgrade, Serbia.
Matic M; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Institute of Medical and Clinical Biochemistry, 11000 Belgrade, Serbia.
Milosevic I; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Clinic of Infectious and Tropical Diseases, Clinical Centre of Serbia, 11000 Belgrade, Serbia.
Viduljevic M; Clinic of Cardiology, Clinical Centre of Serbia, 11000 Belgrade, Serbia.
Stevanovic G; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Clinic of Infectious and Tropical Diseases, Clinical Centre of Serbia, 11000 Belgrade, Serbia.
Ranin J; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Clinic of Infectious and Tropical Diseases, Clinical Centre of Serbia, 11000 Belgrade, Serbia.
Simic T; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Institute of Medical and Clinical Biochemistry, 11000 Belgrade, Serbia.; Department of Medical Sciences, Serbian Academy of Sciences and Arts, 11000 Belgrade, Serbia.
Bukumiric Z; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Institute of Medical Statistics and Informatics, 11000 Belgrade, Serbia.
Savic-Radojevic A; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Institute of Medical and Clinical Biochemistry, 11000 Belgrade, Serbia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 16; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 16.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*
COVID-19*/diagnostic imaging
COVID-19*/genetics
Humans ; Post-Acute COVID-19 Syndrome ; NF-E2-Related Factor 2 ; Glutathione Peroxidase/genetics ; Glutathione Peroxidase/metabolism ; Glutathione Peroxidase GPX1 ; Superoxide Dismutase/metabolism ; Echocardiography
Czasopismo naukowe
Tytuł:
Salvianolic acid B inhibits myocardial I/R-induced ROS generation and cell apoptosis by regulating the TRIM8/GPX1 pathway.
Autorzy:
Lu B; Department of Cardiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Li J; Department of Cardiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Gui M; Department of Cardiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yao L; Department of Cardiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Fan M; Shanghai Leiyunshang Pharmaceutical Co., Ltd., Shanghai, China.
Zhou X; Department of Cardiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Fu D; Department of Cardiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2022 Dec; Vol. 60 (1), pp. 1458-1468.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/drug effects
Benzofurans*/pharmacology
Benzofurans*/therapeutic use
Depsides*/pharmacology
Depsides*/therapeutic use
Glutathione Peroxidase*/genetics
Myocardial Reperfusion Injury*/drug therapy
Myocardial Reperfusion Injury*/genetics
Myocardial Reperfusion Injury*/metabolism
Myocardial Reperfusion Injury*/prevention & control
Animals ; Carrier Proteins/genetics ; Carrier Proteins/metabolism ; Cell Line ; Female ; Humans ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Glutathione Peroxidase GPX1
Czasopismo naukowe
Tytuł:
The boosting effects of melatonin on the expression of related genes to oocyte maturation and antioxidant pathways: a polycystic ovary syndrome- mouse model.
Autorzy:
Nikmard F; Anatomy Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Hosseini E; Department of Obstetrics and Gynecology, Mousavi Hospital, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.; Zanjan Metabolic Diseases Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.
Bakhtiyari M; Anatomy Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Mehr_.; Cellular and Molecular Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Mehr_.
Ashrafi M; Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
Amidi F; Anatomy Department, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Aflatoonian R; Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran. .
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Źródło:
Journal of ovarian research [J Ovarian Res] 2022 Jan 20; Vol. 15 (1), pp. 11. Date of Electronic Publication: 2022 Jan 20.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants/*metabolism
Melatonin/*pharmacology
Oocytes/*drug effects
Oogenesis/*drug effects
Animals ; Apoptosis/drug effects ; Apoptosis/genetics ; Bone Morphogenetic Protein 15/genetics ; Dehydroepiandrosterone/toxicity ; Disease Models, Animal ; Female ; Glutathione Peroxidase/genetics ; Growth Differentiation Factor 9/genetics ; In Vitro Oocyte Maturation Techniques ; Mice ; Oocytes/metabolism ; Oogenesis/genetics ; Polycystic Ovary Syndrome/chemically induced ; Polycystic Ovary Syndrome/genetics ; Polycystic Ovary Syndrome/metabolism ; Polycystic Ovary Syndrome/pathology ; Proto-Oncogene Proteins c-bcl-2/genetics ; Reactive Oxygen Species/metabolism ; Superoxide Dismutase-1/genetics ; bcl-2-Associated X Protein/genetics ; Glutathione Peroxidase GPX1
Czasopismo naukowe
Tytuł:
Risk-focused differences in molecular processes implicated in SARS-CoV-2 infection: corollaries in DNA methylation and gene expression.
Autorzy:
Konwar C; BC Children's Hospital Research Institute (BCCHR), 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.; Centre for Molecular Medicine and Therapeutics, Vancouver, BC, V6H 0B3, Canada.
Asiimwe R; BC Children's Hospital Research Institute (BCCHR), 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.; Centre for Molecular Medicine and Therapeutics, Vancouver, BC, V6H 0B3, Canada.
Inkster AM; BC Children's Hospital Research Institute (BCCHR), 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.; The Department of Medical Genetics, University of British Columbia, Vancouver, BC, V6T 1Z3, Canada.
Merrill SM; BC Children's Hospital Research Institute (BCCHR), 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.; Centre for Molecular Medicine and Therapeutics, Vancouver, BC, V6H 0B3, Canada.
Negri GL; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, V5Z 1L3, Canada.
Aristizabal MJ; BC Children's Hospital Research Institute (BCCHR), 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.; Centre for Molecular Medicine and Therapeutics, Vancouver, BC, V6H 0B3, Canada.; The Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON, M5S 3B2, Canada.; Department of Biology, Queen' University, Kingston, ON, K7L 3N6, Canada.; Program in Child and Brain Development, CIFAR, MaRS Centre, 661 University Ave, Toronto, ON, M5G 1M1, Canada.
Rider CF; The Department of Respiratory Medicine, University of British Columbia, Vancouver, BC, V5Z 1M9, Canada.
MacIsaac JL; BC Children's Hospital Research Institute (BCCHR), 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.; Centre for Molecular Medicine and Therapeutics, Vancouver, BC, V6H 0B3, Canada.
Carlsten C; The Department of Respiratory Medicine, University of British Columbia, Vancouver, BC, V5Z 1M9, Canada.
Kobor MS; BC Children's Hospital Research Institute (BCCHR), 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada. .; Centre for Molecular Medicine and Therapeutics, Vancouver, BC, V6H 0B3, Canada. .; Program in Child and Brain Development, CIFAR, MaRS Centre, 661 University Ave, Toronto, ON, M5G 1M1, Canada. .; The Department of Medical Genetics, University of British Columbia, Vancouver, BC, V6T 1Z3, Canada. .
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Źródło:
Epigenetics & chromatin [Epigenetics Chromatin] 2021 Dec 11; Vol. 14 (1), pp. 54. Date of Electronic Publication: 2021 Dec 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Methylation*
Gene Expression*
SARS-CoV-2*
Sex Characteristics*
COVID-19/*genetics
Adaptor Proteins, Signal Transducing/genetics ; Adolescent ; Adult ; Air Pollutants/adverse effects ; Angiotensin-Converting Enzyme 2/genetics ; Apoptosis Regulatory Proteins/genetics ; COVID-19/virology ; Child ; Child, Preschool ; Chromosomes, Human, X ; Co-Repressor Proteins/genetics ; Female ; Genes, X-Linked ; Glutathione Peroxidase/genetics ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Risk Factors ; Smoking/adverse effects ; Sulfotransferases/genetics ; Young Adult ; beta-Arrestin 2/genetics ; Glutathione Peroxidase GPX1
Czasopismo naukowe
Tytuł:
Comprehensive Evaluation of Biological Effects of Pentathiepins on Various Human Cancer Cell Lines and Insights into Their Mode of Action.
Autorzy:
Wolff L; Pharmazeutische/Medizinische Chemie, Institut für Pharmazie, Universität Greifswald, 17489 Greifswald, Germany.
Bandaru SSM; Bioanorganische Chemie, Institut für Biochemie, Universität Greifswald, 17489 Greifswald, Germany.
Eger E; Pharmazeutische Mikrobiologie, Institut für Pharmazie, Universität Greifswald, 17489 Greifswald, Germany.
Lam HN; Pharmazeutische/Medizinische Chemie, Institut für Pharmazie, Universität Greifswald, 17489 Greifswald, Germany.
Napierkowski M; Pharmazeutische/Medizinische Chemie, Institut für Pharmazie, Universität Greifswald, 17489 Greifswald, Germany.
Baecker D; Pharmazeutische/Medizinische Chemie, Institut für Pharmazie, Universität Greifswald, 17489 Greifswald, Germany.
Schulzke C; Bioanorganische Chemie, Institut für Biochemie, Universität Greifswald, 17489 Greifswald, Germany.
Bednarski PJ; Pharmazeutische/Medizinische Chemie, Institut für Pharmazie, Universität Greifswald, 17489 Greifswald, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 16; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 16.
Typ publikacji:
Journal Article
MeSH Terms:
Glutathione Peroxidase/*antagonists & inhibitors
Thiepins/*chemistry
Thiepins/*pharmacology
Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Glutathione/metabolism ; Glutathione Peroxidase/metabolism ; Humans ; Molecular Structure ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism ; Structure-Activity Relationship ; Glutathione Peroxidase GPX1
Czasopismo naukowe
Tytuł:
Melatonin, Its Beneficial Effects on Embryogenesis from Mitigating Oxidative Stress to Regulating Gene Expression.
Autorzy:
Ivanov D; Department of Neonatology, Saint-Petersburg State Pediatric Medical University, Litovskaya Str., 2, 194100 St. Petersburg, Russia.
Mazzoccoli G; Department of Medical Sciences, Division of Internal Medicine and Chronobiology Laboratory, Fondazione IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy.
Anderson G; Department of Clinical Research, CRC Scotland & London, London E14 6JE, UK.
Linkova N; Department of Biogerontology, Saint Petersburg Institute of Bioregulation and Gerontology, 197110 St. Petersburg, Russia.; Department of Therapy, Geriatry and Anti-Aging Medicine, Academy of Postgraduate Education, Federal Medical Biological Agency, 220013 Moscow, Russia.
Dyatlova A; Department of Biogerontology, Saint Petersburg Institute of Bioregulation and Gerontology, 197110 St. Petersburg, Russia.
Mironova E; Department of Biogerontology, Saint Petersburg Institute of Bioregulation and Gerontology, 197110 St. Petersburg, Russia.; Center of Molecular Biomedicine, Saint-Petersburg Institute of Phthisiopulmonology, Lygovsky Ave. 2-4, 191036 St. Petersburg, Russia.
Polyakova V; Department of Neonatology, Saint-Petersburg State Pediatric Medical University, Litovskaya Str., 2, 194100 St. Petersburg, Russia.
Kvetnoy I; Center of Molecular Biomedicine, Saint-Petersburg Institute of Phthisiopulmonology, Lygovsky Ave. 2-4, 191036 St. Petersburg, Russia.; Department of Pathology, Saint-Petersburg State University, University Embankment, 7/9, 199034 St. Petersburg, Russia.
Evsyukova I; Department of Newborns' Pathology, Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleyevskaya Liniya, 3, 199034 St. Petersburg, Russia.
Carbone A; Department of Medical Sciences, Division of Internal Medicine and Chronobiology Laboratory, Fondazione IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy.
Nasyrov R; Department of Neonatology, Saint-Petersburg State Pediatric Medical University, Litovskaya Str., 2, 194100 St. Petersburg, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 May 30; Vol. 22 (11). Date of Electronic Publication: 2021 May 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Embryo Implantation/*drug effects
Embryonic Development/*drug effects
Gene Expression Regulation, Developmental/*drug effects
Melatonin/*therapeutic use
Ovary/*metabolism
Placenta/*metabolism
Animals ; Embryo, Mammalian ; Embryonic Development/genetics ; Female ; Glutathione Peroxidase/genetics ; Glutathione Peroxidase/metabolism ; Humans ; Infertility, Female/genetics ; Infertility, Female/metabolism ; Infertility, Female/pathology ; Infertility, Female/prevention & control ; Melatonin/metabolism ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; Ovary/growth & development ; Pineal Gland/growth & development ; Pineal Gland/metabolism ; Pregnancy ; Receptor, ErbB-4/genetics ; Receptor, ErbB-4/metabolism ; Superoxide Dismutase-1/genetics ; Superoxide Dismutase-1/metabolism ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism ; Glutathione Peroxidase GPX1
Czasopismo naukowe
Tytuł:
An adenoviral vector encoded with the GPx-1 gene attenuates memory impairments induced by β-amyloid (1-42) in GPx-1 KO mice via activation of M1 mAChR-mediated signalling.
Autorzy:
Shin EJ; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, Republic of Korea.
Lee SH; Department of Pharmacology, College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea.
Sharma N; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, Republic of Korea.
Nguyen BT; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, Republic of Korea.
Chung YH; Department of Anatomy, College of Medicine, Chung-Ang University, Seoul, Korea.
Kang SW; Department of Life Science, College of Natural science, Ewha Womans University, Seoul, Republic of Korea.
Nah SY; Ginsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine and Bio/Molecular Informatics Center, Konkuk University, Seoul, Republic of Korea.
Lee YJ; Clinical Pharmacy, College of Pharmacy, Kangwon National University, Chunchon, Republic of Korea.
Nabeshima T; Advanced Diagnostic System Research Laboratory, Fujita Health University Graduate School of Health Sciences, Aichi, Japan.
Jeong JH; Department of Global Innovative Drugs, Graduate School of Chung-Ang University, College of Medicine, Chung-Ang University, Seoul, Republic of Korea.
Kim HC; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, Republic of Korea.
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Źródło:
Free radical research [Free Radic Res] 2021 Jan; Vol. 55 (1), pp. 11-25. Date of Electronic Publication: 2020 Dec 10.
Typ publikacji:
Journal Article
MeSH Terms:
Amyloid beta-Peptides/*pharmacology
Glutathione Peroxidase/*genetics
Memory Disorders/*chemically induced
Peptide Fragments/*pharmacology
Receptor, Muscarinic M1/*metabolism
Acetylcholine/metabolism ; Adenoviridae/genetics ; Animals ; Disease Models, Animal ; Genetic Vectors/genetics ; Glutathione Peroxidase/administration & dosage ; Glutathione Peroxidase/biosynthesis ; Hippocampus/drug effects ; Hippocampus/metabolism ; Male ; Memory Disorders/genetics ; Mice ; Mice, Knockout ; Signal Transduction/drug effects ; Glutathione Peroxidase GPX1
Czasopismo naukowe
Tytuł:
The Effect of Chronic Mild Stress and Escitalopram on the Expression and Methylation Levels of Genes Involved in the Oxidative and Nitrosative Stresses as Well as Tryptophan Catabolites Pathway in the Blood and Brain Structures.
Autorzy:
Wigner P; Laboratory of Medical Genetics, Faculty of Biology and Environmental Protection, University of Lodz, 90-136 Lodz, Poland.
Synowiec E; Laboratory of Medical Genetics, Faculty of Biology and Environmental Protection, University of Lodz, 90-136 Lodz, Poland.
Jóźwiak P; Department of Cytobiochemistry, Faculty of Biology and Environmental Protection, University of Lodz, 90-136 Lodz, Poland.
Czarny P; Department of Medical Biochemistry, Medical University of Lodz, 90-647 Lodz, Poland.
Bijak M; Biohazard Prevention Centre, Faculty of Biology and Environmental Protection, University of Lodz, 90-136 Lodz, Poland.
Białek K; Laboratory of Medical Genetics, Faculty of Biology and Environmental Protection, University of Lodz, 90-136 Lodz, Poland.
Szemraj J; Department of Medical Biochemistry, Medical University of Lodz, 90-647 Lodz, Poland.
Gruca P; Institute of Pharmacology, Polish Academy of Sciences, 31-343 Krakow, Poland.
Papp M; Institute of Pharmacology, Polish Academy of Sciences, 31-343 Krakow, Poland.
Śliwiński T; Laboratory of Medical Genetics, Faculty of Biology and Environmental Protection, University of Lodz, 90-136 Lodz, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 22; Vol. 22 (1). Date of Electronic Publication: 2020 Dec 22.
Typ publikacji:
Journal Article
MeSH Terms:
Brain/*drug effects
Citalopram/*pharmacology
DNA Methylation/*drug effects
Gene Expression Regulation/*drug effects
Metabolic Networks and Pathways/*genetics
Stress, Psychological/*physiopathology
Tryptophan/*metabolism
Animals ; Antidepressive Agents, Second-Generation/pharmacology ; Brain/metabolism ; Catalase/genetics ; Catalase/metabolism ; Chronic Disease ; Depression/genetics ; Depression/metabolism ; Glutathione Peroxidase/genetics ; Glutathione Peroxidase/metabolism ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/metabolism ; Male ; Nitric Oxide Synthase Type I/genetics ; Nitric Oxide Synthase Type I/metabolism ; Nitrosative Stress ; Oxidative Stress ; Rats, Wistar ; Tryptophan Hydroxylase/genetics ; Tryptophan Hydroxylase/metabolism ; Glutathione Peroxidase GPX1
Czasopismo naukowe
Tytuł:
Association between GPx-1 polymorphisms and personality traits in healthy Chinese-Han subjects.
Autorzy:
Shao X; Department of Psychiatry, The First Affiliated Hospital of China Medical University, Shenyang, China.
Sun D; Department of Psychiatry, The First Affiliated Hospital of China Medical University, Shenyang, China.
Zhang B; Department of Psychiatry, The First Affiliated Hospital of China Medical University, Shenyang, China.
Cheng L; Department of Psychiatry, The First Affiliated Hospital of China Medical University, Shenyang, China.
Yan C; Department of Psychiatry, The First Affiliated Hospital of China Medical University, Shenyang, China.
Zhu G; Department of Psychiatry, The First Affiliated Hospital of China Medical University, Shenyang, China.; Central Laboratory, The First Affiliated Hospital of China Medical University, Shenyang, China.
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Źródło:
Brain and behavior [Brain Behav] 2020 Dec; Vol. 10 (12), pp. e01897. Date of Electronic Publication: 2020 Oct 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Personality*/genetics
Polymorphism, Genetic*
China ; Female ; Genotype ; Glutathione Peroxidase/genetics ; Humans ; Male ; Glutathione Peroxidase GPX1
Czasopismo naukowe
Tytuł:
Antioxidant Function and Metabolomics Study in Mice after Dietary Supplementation with Methionine.
Autorzy:
Yu M; College of Animal Science and Technology, Hunan Agricultural University, Changsha Hunan 410128, China.
Chen H; College of Animal Science and Technology, Hunan Agricultural University, Changsha Hunan 410128, China.
Liu P; College of Animal Science and Technology, Hunan Agricultural University, Changsha Hunan 410128, China.
Yang M; College of Animal Science and Technology, Hunan Agricultural University, Changsha Hunan 410128, China.
Zou L; College of Animal Science and Technology, Hunan Agricultural University, Changsha Hunan 410128, China.
Xiao D; College of Animal Science and Technology, Hunan Agricultural University, Changsha Hunan 410128, China.; Hunan Collaborative Innovation Center of Animal Production Safety, Changsha Hunan 410128, China.
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Źródło:
BioMed research international [Biomed Res Int] 2020 Oct 20; Vol. 2020, pp. 9494528. Date of Electronic Publication: 2020 Oct 20 (Print Publication: 2020).
Typ publikacji:
Journal Article
MeSH Terms:
Dietary Supplements*
Gene Expression Regulation/*drug effects
Jejunum/*drug effects
Liver/*drug effects
Metabolome/*drug effects
Methionine/*metabolism
Aminoisobutyric Acids/metabolism ; Animals ; Antioxidants/metabolism ; Asparagine/metabolism ; Benzyl Alcohols/metabolism ; Diet/methods ; Female ; Glucosides/metabolism ; Glutathione Peroxidase/genetics ; Glutathione Peroxidase/metabolism ; Inosine Monophosphate/metabolism ; Jejunum/metabolism ; Kelch-Like ECH-Associated Protein 1/genetics ; Kelch-Like ECH-Associated Protein 1/metabolism ; Lactones/metabolism ; Liver/metabolism ; Maltose/metabolism ; Metabolome/physiology ; Methionine/administration & dosage ; Mice ; Mice, Inbred ICR ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; Phospholipid Hydroperoxide Glutathione Peroxidase/genetics ; Phospholipid Hydroperoxide Glutathione Peroxidase/metabolism ; Pyridones/metabolism ; Superoxide Dismutase-1/genetics ; Superoxide Dismutase-1/metabolism ; Glutathione Peroxidase GPX1
Czasopismo naukowe
Tytuł:
Quercetin-conjugated superparamagnetic iron oxide nanoparticles (QCSPIONs) increases Nrf2 expression via miR-27a mediation to prevent memory dysfunction in diabetic rats.
Autorzy:
Ebrahimpour S; Department of Cell and Molecular Biology & Microbiology, Faculty of Biological Science and Technology, University of Isfahan, HezarJarib Street, P.O. Box: 8174673441, 81746-73441, Isfahan, Iran.
Shahidi SB; Department of Cell and Molecular Biology & Microbiology, Faculty of Biological Science and Technology, University of Isfahan, HezarJarib Street, P.O. Box: 8174673441, 81746-73441, Isfahan, Iran.
Abbasi M; Department of Cell and Molecular Biology & Microbiology, Faculty of Biological Science and Technology, University of Isfahan, HezarJarib Street, P.O. Box: 8174673441, 81746-73441, Isfahan, Iran.
Tavakoli Z; Department of Cell and Molecular Biology & Microbiology, Faculty of Biological Science and Technology, University of Isfahan, HezarJarib Street, P.O. Box: 8174673441, 81746-73441, Isfahan, Iran.
Esmaeili A; Department of Cell and Molecular Biology & Microbiology, Faculty of Biological Science and Technology, University of Isfahan, HezarJarib Street, P.O. Box: 8174673441, 81746-73441, Isfahan, Iran. .
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Źródło:
Scientific reports [Sci Rep] 2020 Sep 29; Vol. 10 (1), pp. 15957. Date of Electronic Publication: 2020 Sep 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Magnetic Iron Oxide Nanoparticles/*administration & dosage
Memory/*drug effects
MicroRNAs/*metabolism
NF-E2-Related Factor 2/*biosynthesis
Quercetin/*administration & dosage
Animals ; Antioxidants/pharmacology ; Catalase/metabolism ; Cells, Cultured ; Diabetes Mellitus, Experimental/genetics ; Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Experimental/pathology ; Gene Expression ; Glutathione Peroxidase/metabolism ; Magnetic Iron Oxide Nanoparticles/chemistry ; Male ; Memory/physiology ; MicroRNAs/genetics ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; Oxidative Stress/drug effects ; Quercetin/chemistry ; Rats ; Rats, Wistar ; Superoxide Dismutase-1/metabolism ; Glutathione Peroxidase GPX1
Czasopismo naukowe
Tytuł:
The BXD21/TyJ recombinant inbred strain as a model for innate inflammatory response in distinct brain regions.
Autorzy:
López-Granero C; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA. .; Departamento de Psicología y Sociología, Universidad de Zaragoza, Campus Ciudad Escolar, 44003, Teruel, Spain. .
Ferrer B; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
Dos Santos AA; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
Barrasa A; Departamento de Psicología y Sociología, Universidad de Zaragoza, Campus Ciudad Escolar, 44003, Teruel, Spain.
Aschner M; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA. .
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Źródło:
Scientific reports [Sci Rep] 2020 Aug 05; Vol. 10 (1), pp. 13168. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain/*metabolism
Cytokines/*genetics
Gene Expression Profiling/*methods
Glutathione Peroxidase/*genetics
Inflammation/*genetics
Kelch-Like ECH-Associated Protein 1/*genetics
NF-E2-Related Factor 2/*genetics
Animals ; Female ; Gene Expression Regulation ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Inbred Strains ; Organ Specificity ; Oxidative Stress ; Glutathione Peroxidase GPX1
Czasopismo naukowe
Tytuł:
Association of Nrf2 , SOD2 and GPX1 Polymorphisms with Biomarkers of Oxidative Distress and Survival in End-Stage Renal Disease Patients.
Autorzy:
Jerotic D; Institute of Medical and Clinical Biochemistry, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Matic M; Institute of Medical and Clinical Biochemistry, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Suvakov S; Institute of Medical and Clinical Biochemistry, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Vucicevic K; Department of Pharmacokinetics and Clinical Pharmacy, Faculty of Pharmacy, University of Belgrade, 11000 Belgrade, Serbia.
Damjanovic T; Clinical Department for Renal Diseases, Zvezdara University Medical Center, 11000 Belgrade, Serbia.
Savic-Radojevic A; Institute of Medical and Clinical Biochemistry, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Pljesa-Ercegovac M; Institute of Medical and Clinical Biochemistry, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Coric V; Institute of Medical and Clinical Biochemistry, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Stefanovic A; Department of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, 11000 Belgrade, Serbia.
Ivanisevic J; Department of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, 11000 Belgrade, Serbia.
Jelic-Ivanovic Z; Department of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, 11000 Belgrade, Serbia.
McClements L; School of Life Sciences, Faculty of Science, University of Technology Sydney, NSW 2007 Sidney, Australia.
Dimkovic N; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Clinical Department for Renal Diseases, Zvezdara University Medical Center, 11000 Belgrade, Serbia.
Simic T; Institute of Medical and Clinical Biochemistry, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia. .; Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia. .; Serbian Academy of Sciences and Arts, 11000 Belgrade, Serbia. .
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Źródło:
Toxins [Toxins (Basel)] 2019 Jul 23; Vol. 11 (7). Date of Electronic Publication: 2019 Jul 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glutathione Peroxidase/*genetics
Kidney Failure, Chronic/*genetics
Kidney Failure, Chronic/*mortality
NF-E2-Related Factor 2/*genetics
Superoxide Dismutase/*genetics
Aged ; Biomarkers ; Female ; Genotype ; Humans ; Kaplan-Meier Estimate ; Kidney Failure, Chronic/therapy ; Male ; Middle Aged ; Oxidative Stress ; Polymorphism, Genetic ; Polymorphism, Single Nucleotide ; Renal Dialysis ; Risk Factors ; Glutathione Peroxidase GPX1
Czasopismo naukowe
Tytuł:
Selenium‐binding protein 1 inhibits malignant progression and induces apoptosis via distinct mechanisms in non‐small cell lung cancer
Autorzy:
Ying Zhu
Qiang Pu
Qiongyin Zhang
Yang Liu
Yongfang Ma
Yue Yuan
Lunxu Liu
Wen Zhu
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Temat:
caspase‐3 pathway
GPX1
NSCLC
PI3K/AKT/mTOR pathway
SELENBP1
tumor suppressor
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Źródło:
Cancer Medicine, Vol 12, Iss 16, Pp 17149-17170 (2023)
Opis pliku:
electronic resource
Relacje:
https://doaj.org/toc/2045-7634
Dostęp URL:
https://doaj.org/article/a4431151e7264c11b0ebfe7a783cd2b7  Link otwiera się w nowym oknie
Czasopismo naukowe
Tytuł:
Selenoprotein P inhibits cell proliferation and ROX production in HCC cells.
Autorzy:
Wang J; Department of Laboratory Medicine, Affiliated Hospital of Nantong University, Nantong, Jiangsu, People's Republic of China.
Shen P; Department of Laboratory Medicine, Affiliated Hospital of Nantong University, Nantong, Jiangsu, People's Republic of China.
Liao S; Department of Laboratory Medicine, Affiliated Hospital of Nantong University, Nantong, Jiangsu, People's Republic of China.
Duan L; Department of Medical Informatics, School of Medicine, Nantong University, Nantong, Jiangsu, People's Republic of China.
Zhu D; Department of Pathogen Biology, School of Medicine, Nantong University, Nantong, Jiangsu, People's Republic of China.
Chen J; Department of Pathogen Biology, School of Medicine, Nantong University, Nantong, Jiangsu, People's Republic of China.
Chen L; Department of Pathogen Biology, School of Medicine, Nantong University, Nantong, Jiangsu, People's Republic of China.
Sun X; Department of Pathogen Biology, School of Medicine, Nantong University, Nantong, Jiangsu, People's Republic of China.
Duan Y; Department of Pathogen Biology, School of Medicine, Nantong University, Nantong, Jiangsu, People's Republic of China.
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Źródło:
PloS one [PLoS One] 2020 Jul 31; Vol. 15 (7), pp. e0236491. Date of Electronic Publication: 2020 Jul 31 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular/*genetics
Glutathione Peroxidase/*genetics
Liver Neoplasms/*genetics
Selenoprotein P/*genetics
Carcinoma, Hepatocellular/pathology ; Cell Proliferation/genetics ; Female ; Gene Expression Regulation, Neoplastic/genetics ; Hep G2 Cells ; Humans ; Ki-67 Antigen/genetics ; Liver/metabolism ; Liver/pathology ; Liver Neoplasms/pathology ; Male ; Glutathione Peroxidase GPX1
Czasopismo naukowe
Tytuł:
β-glucan administration improves growth performance and gut health in New Zealand White and APRI rabbits with different breed responses.
Autorzy:
Abo Ghanima MM; Department of Animal Husbandry and Animal Wealth Development, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt.
Abd El-Aziz AH; Department of Animal Husbandry and Animal Wealth Development, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt.
Noreldin AE; Department of Histology and Cytology, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt.
Atta MS; Department of Physiology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt.
Mousa SA; Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, Rensselaer, NY, United States of America.
El-Far AH; Department of Biochemistry, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt.
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Źródło:
PloS one [PLoS One] 2020 Jun 10; Vol. 15 (6), pp. e0234076. Date of Electronic Publication: 2020 Jun 10 (Print Publication: 2020).
Typ publikacji:
Journal Article
MeSH Terms:
Intestinal Mucosa/*drug effects
Weight Gain/*drug effects
beta-Glucans/*pharmacology
Adaptive Immunity/drug effects ; Administration, Oral ; Animals ; Duodenum/metabolism ; Duodenum/pathology ; Glutathione Peroxidase/genetics ; Glutathione Peroxidase/metabolism ; Interleukin-18/metabolism ; Intestinal Mucosa/metabolism ; Male ; Occludin/genetics ; Occludin/metabolism ; Rabbits ; Superoxide Dismutase-1/genetics ; Superoxide Dismutase-1/metabolism ; Up-Regulation/drug effects ; Glutathione Peroxidase GPX1
Czasopismo naukowe
Tytuł:
Glutathione peroxidase-1 overexpression reduces oxidative stress, and improves pathology and proteome remodeling in the kidneys of old mice.
Autorzy:
Chu Y; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Lan RS; Proteomics Core, Department of Biochemistry and Molecular Biology, University of Arkansas Medical Sciences College of Medicine, Little Rock, Arkansas.
Huang R; Department of Statistics and Actuarial Science, College of Liberal Arts and Sciences, University of Iowa, Iowa City, Iowa.
Feng H; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Kumar R; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Dayal S; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Chan KS; Department of Statistics and Actuarial Science, College of Liberal Arts and Sciences, University of Iowa, Iowa City, Iowa.
Dai DF; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
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Źródło:
Aging cell [Aging Cell] 2020 Jun; Vol. 19 (6), pp. e13154. Date of Electronic Publication: 2020 May 13.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Glutathione Peroxidase/*biosynthesis
Kidney/*metabolism
Proteome/*metabolism
Reactive Oxygen Species/*metabolism
Age Factors ; Animals ; Glutathione Peroxidase/genetics ; Glutathione Peroxidase/metabolism ; Kidney/enzymology ; Kidney/pathology ; Mice ; Mice, Transgenic ; Oxidative Stress/physiology ; Proteomics ; Glutathione Peroxidase GPX1
Czasopismo naukowe

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