Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""heme"" wg kryterium: Temat


Tytuł :
The Worst Things in Life are Free: The Role of Free Heme in Sickle Cell Disease.
Autorzy :
Gbotosho OT; Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Kapetanaki MG; Pittsburgh Heart, Lung, Blood, and Vascular Medicine Institute, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Kato GJ; Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.; Pittsburgh Heart, Lung, Blood, and Vascular Medicine Institute, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Pokaż więcej
Źródło :
Frontiers in immunology [Front Immunol] 2021 Jan 27; Vol. 11, pp. 561917. Date of Electronic Publication: 2021 Jan 27 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Disease Progression*
Hemolysis*
Anemia, Sickle Cell/*metabolism
Heme/*metabolism
Anemia, Sickle Cell/complications ; Anemia, Sickle Cell/pathology ; Animals ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/metabolism ; Heme Oxygenase-1/metabolism ; Hemopexin/metabolism ; Humans ; Hypertension, Pulmonary/etiology ; Hypertension, Pulmonary/metabolism ; Inflammation/metabolism ; Interleukin-6/metabolism ; Oxidative Stress ; Placenta Growth Factor/metabolism ; Respiratory Hypersensitivity/etiology ; Respiratory Hypersensitivity/metabolism
Czasopismo naukowe
Tytuł :
Heme oxygenase-2 is post-translationally regulated by heme occupancy in the catalytic site.
Autorzy :
Liu L; Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, USA.
Dumbrepatil AB; Department of Chemistry, College of Literature, Science and Arts, University of Michigan, Ann Arbor, Michigan, USA.
Fleischhacker AS; Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, USA.
Marsh ENG; Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, USA; Department of Chemistry, College of Literature, Science and Arts, University of Michigan, Ann Arbor, Michigan, USA.
Ragsdale SW; Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: .
Pokaż więcej
Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Dec 11; Vol. 295 (50), pp. 17227-17240. Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Proteolysis*
Heme/*metabolism
Heme Oxygenase (Decyclizing)/*metabolism
Proteasome Endopeptidase Complex/*metabolism
Catalytic Domain ; Enzyme Stability ; HEK293 Cells ; Heme/genetics ; Heme Oxygenase (Decyclizing)/genetics ; Heme Oxygenase-1/genetics ; Heme Oxygenase-1/metabolism ; Humans ; Proteasome Endopeptidase Complex/genetics
Czasopismo naukowe
Tytuł :
Heme-Oxygenase-1.
Autorzy :
Facchinetti MM; Dpto. de Biología, Bioquímica y Farmacia (UNS), Laboratorio de Biología del Cáncer, Instituto de Investigaciones Bioquímicas de Bahía Blanca (INIBIBB), Universidad Nacional del Sur (UNS)-CONICET, Bahía Blanca, Argentina.
Pokaż więcej
Źródło :
Antioxidants & redox signaling [Antioxid Redox Signal] 2020 Jun 10; Vol. 32 (17), pp. 1239-1242.
Typ publikacji :
Editorial; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Heme Oxygenase-1*
Prostatic Neoplasms*
Animals ; Bone Remodeling ; Heme ; Heme Oxygenase (Decyclizing) ; Humans ; Male ; Mice
Raport
Tytuł :
Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis.
Autorzy :
Du J; Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, China.
Ren W; Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, China.
Zhang Q; Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, China.
Fu N; Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, China.
Han F; Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, China.
Cui P; Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, China.
Li W; Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, China.
Kong L; Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, China.
Zhao S; Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, China.
Wang R; Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, China.
Zhang Y; Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, China.
Yang L; Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, China.
Kong L; Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, China.
Nan Y; Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, China.
Pokaż więcej
Źródło :
BioMed research international [Biomed Res Int] 2020 May 01; Vol. 2020, pp. 4910601. Date of Electronic Publication: 2020 May 01 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Heme Oxygenase-1*/genetics
Heme Oxygenase-1*/metabolism
Membrane Proteins*/genetics
Membrane Proteins*/metabolism
Wnt Signaling Pathway*/genetics
Wnt Signaling Pathway*/physiology
Liver Cirrhosis/*metabolism
Non-alcoholic Fatty Liver Disease/*metabolism
Animals ; Cell Line ; Gene Knockdown Techniques ; Heme Oxygenase (Decyclizing)/genetics ; Heme Oxygenase (Decyclizing)/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Rats
Czasopismo naukowe
Tytuł :
Exacerbation of Neonatal Hemolysis and Impaired Renal Iron Handling in Heme Oxygenase 1-Deficient Mice.
Autorzy :
Bednarz A; Department of Genetics and Evolution, Institute of Zoology and Biomedical Research, Jagiellonian University, Gronostajowa 9, 30-387 Kraków, Poland.
Lipiński P; Department of Molecular Biology, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Jastrzębiec, 05-552 Magdalenka, Poland.
Starzyński RR; Department of Molecular Biology, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Jastrzębiec, 05-552 Magdalenka, Poland.
Tomczyk M; Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.
Kraszewska I; Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.
Herman S; Department of Genetics and Evolution, Institute of Zoology and Biomedical Research, Jagiellonian University, Gronostajowa 9, 30-387 Kraków, Poland.
Kowalski K; Department of Genetics and Evolution, Institute of Zoology and Biomedical Research, Jagiellonian University, Gronostajowa 9, 30-387 Kraków, Poland.
Gruca E; Department of Genetics and Evolution, Institute of Zoology and Biomedical Research, Jagiellonian University, Gronostajowa 9, 30-387 Kraków, Poland.
Jończy A; Department of Molecular Biology, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Jastrzębiec, 05-552 Magdalenka, Poland.
Mazgaj R; Department of Molecular Biology, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Jastrzębiec, 05-552 Magdalenka, Poland.
Szudzik M; Department of Molecular Biology, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Jastrzębiec, 05-552 Magdalenka, Poland.
Rajfur Z; Department of Molecular and Interfacial Biophysics, Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, Łojasiewicza 11, 30-348 Kraków, Poland.
Baster Z; Department of Molecular and Interfacial Biophysics, Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, Łojasiewicza 11, 30-348 Kraków, Poland.
Józkowicz A; Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.
Lenartowicz M; Department of Genetics and Evolution, Institute of Zoology and Biomedical Research, Jagiellonian University, Gronostajowa 9, 30-387 Kraków, Poland.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 20; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 20.
Typ publikacji :
Journal Article
MeSH Terms :
Hemolysis*
Heme Oxygenase-1/*deficiency
Iron/*metabolism
Kidney/*metabolism
Renal Insufficiency/*metabolism
Anemia/blood ; Anemia/therapy ; Animals ; Animals, Newborn ; Erythrocyte Count ; Female ; Heme/metabolism ; Heme Oxygenase-1/genetics ; Iron/urine ; Kidney/pathology ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Renal Insufficiency/genetics ; Renal Insufficiency/therapy
Czasopismo naukowe
Tytuł :
Heme Degradation in Pathophysiology of and Countermeasures to Inflammation-Associated Disease.
Autorzy :
Haines DD; Advanced Biotherapeutics, London W2 1EB, UK.; Department of Pharmacology, Faculty of Pharmacy, University of Debrecen, 4032 Debrecen, Hungary.
Tosaki A; Department of Pharmacology, Faculty of Pharmacy, University of Debrecen, 4032 Debrecen, Hungary.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 18; Vol. 21 (24). Date of Electronic Publication: 2020 Dec 18.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cardiovascular Diseases/*drug therapy
Cardiovascular Diseases/*physiopathology
Flavonoids/*pharmacology
Heme/*metabolism
Inflammation/*drug therapy
Inflammation/*physiopathology
Nervous System Diseases/*drug therapy
Nervous System Diseases/*physiopathology
Animals ; Heme Oxygenase-1/metabolism ; Humans
Czasopismo naukowe
Tytuł :
Heme oxygenase-1 modulation: A potential therapeutic target for COVID-19 and associated complications.
Autorzy :
Singh D; Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India.
Wasan H; Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India.
Reeta KH; Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India. Electronic address: .
Pokaż więcej
Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2020 Dec; Vol. 161, pp. 263-271. Date of Electronic Publication: 2020 Oct 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
COVID-19/*immunology
Fibrinolytic Agents/*metabolism
Heme Oxygenase-1/*metabolism
Interferon Type I/*immunology
SARS-CoV-2/*growth & development
Antiviral Agents/metabolism ; COVID-19/drug therapy ; Disseminated Intravascular Coagulation/prevention & control ; Heme/metabolism ; Heme Oxygenase-1/genetics ; Humans ; Polymorphism, Single Nucleotide/genetics ; SARS-CoV-2/drug effects
Czasopismo naukowe
Tytuł :
Sevoflurane protects the liver from ischemia-reperfusion injury by regulating Nrf2/HO-1 pathway.
Autorzy :
Ma H; Department of Anesthesiology, The First Affiliated Hospital of Harbin Medical University, No.23, Youzheng Street, Nangang District, Harbin, Heilongjiang, 150001, China.
Yang B; Department of Neursurgery, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, No.26, Heping Road, Dongli District, Harbin, Heilongjiang, 150040, China.
Yu L; Department of Anesthesiology, The First Affiliated Hospital of Harbin Medical University, No.23, Youzheng Street, Nangang District, Harbin, Heilongjiang, 150001, China.
Gao Y; Department of Anesthesiology, The First Affiliated Hospital of Harbin Medical University, No.23, Youzheng Street, Nangang District, Harbin, Heilongjiang, 150001, China.
Ye X; Laboratory of Hemooncology, The First Affiliated Hospital of Harbin Medical University, No.23, Youzheng Street, Nangang District, Harbin, Heilongjiang, 150001, China.
Liu Y; Department of Anesthesiology, The First Affiliated Hospital of Harbin Medical University, No.23, Youzheng Street, Nangang District, Harbin, Heilongjiang, 150001, China.
Li Z; Department of Tumor Endoscopic Surgery, The First Affiliated Hospital of Harbin Medical University, No.23, Youzheng Street, Nangang District, Harbin, Heilongjiang, 150001, China.
Li H; Department of Neurobiology, Harbin Medical University, No.194, Xuefu Road, Harbin, Heilongjiang, 150001, China.
Li E; Department of Anesthesiology, The First Affiliated Hospital of Harbin Medical University, No.23, Youzheng Street, Nangang District, Harbin, Heilongjiang, 150001, China. Electronic address: .
Pokaż więcej
Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 May 05; Vol. 898, pp. 173932. Date of Electronic Publication: 2021 Feb 23.
Typ publikacji :
Journal Article
MeSH Terms :
Heme Oxygenase (Decyclizing)/*metabolism
Heme Oxygenase-1/*metabolism
Hepatocytes/*drug effects
Liver/*drug effects
Liver Diseases/*prevention & control
Membrane Proteins/*metabolism
NF-E2-Related Factor 2/*metabolism
Reperfusion Injury/*prevention & control
Sevoflurane/*pharmacology
Animals ; Apoptosis/drug effects ; Cell Line ; Disease Models, Animal ; Heme Oxygenase (Decyclizing)/genetics ; Heme Oxygenase-1/genetics ; Hepatocytes/enzymology ; Hepatocytes/pathology ; Inflammation Mediators/metabolism ; Liver/enzymology ; Liver/pathology ; Liver Diseases/enzymology ; Liver Diseases/pathology ; Male ; Membrane Proteins/genetics ; Mice ; Oxidative Stress/drug effects ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Reperfusion Injury/enzymology ; Reperfusion Injury/pathology ; Signal Transduction
Czasopismo naukowe
Tytuł :
Heme as Possible Contributing Factor in the Evolvement of Shiga-Toxin Escherichia coli Induced Hemolytic-Uremic Syndrome.
Autorzy :
Wijnsma KL; Department of Pediatric Nephrology, Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.
Veissi ST; Department of Pediatric Nephrology, Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.
de Wijs S; Department of Pediatric Nephrology, Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.
van der Velden T; Department of Pediatric Nephrology, Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.
Volokhina EB; Department of Pediatric Nephrology, Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.; Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands.
Wagener FADTG; Department of Dentistry-Orthodontics and Craniofacial Biology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.
van de Kar NCAJ; Department of Pediatric Nephrology, Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.
van den Heuvel LP; Department of Pediatric Nephrology, Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.; Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands.; Department of Development and Regeneration, University Hospital Leuven, Leuven, Belgium.
Pokaż więcej
Źródło :
Frontiers in immunology [Front Immunol] 2020 Dec 22; Vol. 11, pp. 547406. Date of Electronic Publication: 2020 Dec 22 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Susceptibility*
Heme/*metabolism
Hemolytic-Uremic Syndrome/*etiology
Hemolytic-Uremic Syndrome/*metabolism
Shiga-Toxigenic Escherichia coli/*physiology
Apoptosis ; Biomarkers ; Child ; Child, Preschool ; Endothelial Cells/metabolism ; Female ; Heme Oxygenase-1/metabolism ; Hemolytic-Uremic Syndrome/diagnosis ; Hemolytic-Uremic Syndrome/therapy ; Humans ; Infant ; Male ; Oxidation-Reduction ; Phenotype ; Protein Transport ; Reactive Oxygen Species/metabolism ; Stress, Physiological ; Thromboplastin/metabolism
Czasopismo naukowe
Tytuł :
Single-arm, open-label pilot intervention study to investigate an effect of oral 5-aminolevulinic acid plus sodium ferrous citrate on glucocorticoid reduction in patients with adult-onset Still disease: Study protocol for clinical trial (SPIRIT compliant).
Autorzy :
Sumiyoshi R; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences.; Nagasaki University Hospital, Clinical Research Center.
Koga T; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences.; Center for Bioinformatics and Molecular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Shimizu T; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences.; Nagasaki University Hospital, Clinical Research Center.
Sato S; Nagasaki University Hospital, Clinical Research Center.
Tashiro S; Nagasaki University Hospital, Clinical Research Center.
Hosogaya N; Nagasaki University Hospital, Clinical Research Center.
Yamamoto H; Nagasaki University Hospital, Clinical Research Center.
Kawakami A; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences.
Pokaż więcej
Źródło :
Medicine [Medicine (Baltimore)] 2020 Dec 11; Vol. 99 (50), pp. e22708.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Aminolevulinic Acid/*pharmacology
Ferrous Compounds/*pharmacology
Heme Oxygenase-1/*drug effects
Still's Disease, Adult-Onset/*drug therapy
Administration, Oral ; Adult ; Drug Therapy, Combination ; Female ; Glucocorticoids/therapeutic use ; Heme/biosynthesis ; Heme Oxygenase-1/metabolism ; Humans ; Japan/epidemiology ; Male ; Photosensitizing Agents/pharmacology ; Pilot Projects ; Safety ; Trace Elements/pharmacology ; Treatment Outcome
Czasopismo naukowe
Tytuł :
A heme-binding protein produced by Haemophilus haemolyticus inhibits non-typeable Haemophilus influenzae.
Autorzy :
Latham RD; School of Medicine, University of Tasmania, Hobart, Australia.
Torrado M; School of Life and Environmental Sciences, University of Sydney, Sydney, Australia.
Atto B; School of Health Sciences, University of Tasmania, Launceston, Australia.
Walshe JL; School of Life and Environmental Sciences, University of Sydney, Sydney, Australia.
Wilson R; Central Science Laboratory, University of Tasmania, Hobart, Australia.
Guss JM; School of Life and Environmental Sciences, University of Sydney, Sydney, Australia.
Mackay JP; School of Life and Environmental Sciences, University of Sydney, Sydney, Australia.
Tristram S; School of Health Sciences, University of Tasmania, Launceston, Australia.
Gell DA; School of Medicine, University of Tasmania, Hobart, Australia.
Pokaż więcej
Źródło :
Molecular microbiology [Mol Microbiol] 2020 Feb; Vol. 113 (2), pp. 381-398. Date of Electronic Publication: 2019 Dec 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Heme-Binding Proteins*/chemistry
Heme-Binding Proteins*/isolation & purification
Heme-Binding Proteins*/pharmacology
Haemophilus/*metabolism
Haemophilus influenzae/*drug effects
Bacterial Proteins/chemistry ; Bacterial Proteins/isolation & purification ; Bacterial Proteins/pharmacology ; Haemophilus Infections/microbiology ; Haemophilus Infections/prevention & control ; Haemophilus influenzae/growth & development ; Heme/metabolism ; Humans
SCR Organism :
Haemophilus haemolyticus
Czasopismo naukowe
Tytuł :
Heme Oxygenase-1 in Macrophages Impairs the Perfusion Recovery After Hindlimb Ischemia by Suppressing Autolysosome-Dependent Degradation of NLRP3.
Autorzy :
Ma Y; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jia L; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wang Y; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Ji Y; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Chen J; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Ma H; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Lin X; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhang Y; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Li W; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Ni H; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xie L; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xie Y; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xiang M; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Pokaż więcej
Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 May 05; Vol. 41 (5), pp. 1710-1723. Date of Electronic Publication: 2021 Mar 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Heme Oxygenase-1/*metabolism
Inflammasomes/*metabolism
Ischemia/*enzymology
Lysosomes/*enzymology
Macrophages/*enzymology
Membrane Proteins/*metabolism
Muscle, Skeletal/*blood supply
Muscle, Skeletal/*enzymology
NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism
Animals ; Cells, Cultured ; Databases, Genetic ; Disease Models, Animal ; Heme Oxygenase-1/genetics ; Hindlimb ; Humans ; Inflammasomes/genetics ; Inflammation Mediators/metabolism ; Ischemia/genetics ; Ischemia/physiopathology ; Male ; Membrane Proteins/genetics ; Mice, Inbred C57BL ; Mice, Knockout ; Muscle, Skeletal/physiopathology ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; Neovascularization, Physiologic ; Proteolysis ; Recovery of Function ; Regional Blood Flow
Czasopismo naukowe
Tytuł :
Heme supplementation ameliorates lupus nephritis through rectifying the disorder of splenocytes and alleviating renal inflammation and oxidative damage.
Autorzy :
Wu B; Laboratory of Anti-inflammation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China; School of Pharmacy, University of Chinese Academy of Sciences, Beijing, China.
Wu Y; Laboratory of Anti-inflammation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Fan C; Laboratory of Anti-inflammation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Feng C; Laboratory of Anti-inflammation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Wang H; Laboratory of Anti-inflammation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China; School of Pharmacy, University of Chinese Academy of Sciences, Beijing, China.
Bai F; Laboratory of Anti-inflammation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China; School of Pharmacy, University of Chinese Academy of Sciences, Beijing, China.
Zuo J; School of Pharmacy, University of Chinese Academy of Sciences, Beijing, China; Laboratory of Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. Electronic address: .
Tang W; Laboratory of Anti-inflammation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China; School of Pharmacy, University of Chinese Academy of Sciences, Beijing, China. Electronic address: .
Pokaż więcej
Źródło :
International immunopharmacology [Int Immunopharmacol] 2021 May; Vol. 94, pp. 107482. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article
MeSH Terms :
Heme/*immunology
Lupus Nephritis/*immunology
Spleen/*immunology
Animals ; Cell Line ; Cytokines/immunology ; Female ; Heme/therapeutic use ; Humans ; Kidney/drug effects ; Kidney/immunology ; Lupus Nephritis/drug therapy ; Lupus Nephritis/pathology ; Mice, Inbred MRL lpr ; Oxidative Stress/drug effects ; Spleen/drug effects ; Spleen/pathology
Czasopismo naukowe
Tytuł :
Inhibition of endotoxin-induced acute lung injury in rats by bone marrow-derived mesenchymal stem cells: Role of Nrf2/HO-1 signal axis in inhibition of NLRP3 activation.
Autorzy :
Lei L; Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, Fujian, 350001, China.
Guo Y; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, Fujian, 350001, China.
Lin J; The First Clinical Medical College of Fujian Medical University, Fuzhou, Fujian, 350005, China.
Lin X; The First Clinical Medical College of Fujian Medical University, Fuzhou, Fujian, 350005, China.
He S; The First Clinical Medical College of Fujian Medical University, Fuzhou, Fujian, 350005, China.
Qin Z; Department of Anesthesiology, Nanfang Hospital, Southern Medical University, 1838 North Guangzhou Avenue, Guangzhou, Guangdong, 510515, China. Electronic address: .
Lin Q; Department of Anesthesiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350005, China; Anesthesiology Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, 350005, China. Electronic address: .
Pokaż więcej
Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Apr 30; Vol. 551, pp. 7-13. Date of Electronic Publication: 2021 Mar 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acute Lung Injury/*metabolism
Acute Lung Injury/*prevention & control
Bone Marrow Cells/*cytology
Endotoxins/*adverse effects
Heme Oxygenase (Decyclizing)/*metabolism
Mesenchymal Stem Cells/*metabolism
NF-E2-Related Factor 2/*metabolism
NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism
Acute Lung Injury/chemically induced ; Animals ; Antioxidants/metabolism ; Capillary Permeability/drug effects ; Gene Expression Regulation ; Heme Oxygenase (Decyclizing)/antagonists & inhibitors ; Inflammasomes/drug effects ; Inflammasomes/metabolism ; Inflammation/chemically induced ; Inflammation/metabolism ; Lung/blood supply ; Lung/drug effects ; Lung/metabolism ; Lung/pathology ; Male ; Mesenchymal Stem Cells/cytology ; NF-E2-Related Factor 2/antagonists & inhibitors ; Oxidative Stress/drug effects ; Rats ; Rats, Sprague-Dawley ; Signal Transduction ; Survival Rate
Czasopismo naukowe
Tytuł :
Fluorescence Response and Self-Assembly of a Tweezer-Type Synthetic Receptor Triggered by Complexation with Heme and Its Catabolites.
Autorzy :
Hisamatsu Y; Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, 467-8603, Japan.
Otani K; Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, 467-8603, Japan.
Takase H; Graduate School of Medical Sciences, Nagoya City University, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan.
Umezawa N; Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, 467-8603, Japan.
Higuchi T; Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, 467-8603, Japan.
Pokaż więcej
Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 Apr 12; Vol. 27 (21), pp. 6489-6499. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji :
Journal Article
MeSH Terms :
Heme*
Receptors, Artificial*
Flavin Mononucleotide ; Fluorescence ; NAD
Czasopismo naukowe
Tytuł :
α 1 -Microglobulin (A1M) Protects Human Proximal Tubule Epithelial Cells from Heme-Induced Damage In Vitro.
Autorzy :
Kristiansson A; Section for Infection Medicine, Department of Clinical Sciences, Lund University, 221 84 Lund, Sweden.; Division of Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University, 221 84 Lund, Sweden.
Davidsson S; Section for Infection Medicine, Department of Clinical Sciences, Lund University, 221 84 Lund, Sweden.
Johansson ME; Section for Infection Medicine, Department of Clinical Sciences, Lund University, 221 84 Lund, Sweden.
Piel S; Mitochondrial Medicine, Department of Clinical Sciences Lund, Lund University, 221 84 Lund, Sweden.; Department of Anesthesiology and Critical Care Medicine, Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Elmér E; Mitochondrial Medicine, Department of Clinical Sciences Lund, Lund University, 221 84 Lund, Sweden.
Hansson MJ; Mitochondrial Medicine, Department of Clinical Sciences Lund, Lund University, 221 84 Lund, Sweden.
Åkerström B; Section for Infection Medicine, Department of Clinical Sciences, Lund University, 221 84 Lund, Sweden.
Gram M; Department of Clinical Sciences Lund, Pediatrics, Lund University, 221 84 Lund, Sweden.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Aug 13; Vol. 21 (16). Date of Electronic Publication: 2020 Aug 13.
Typ publikacji :
Journal Article
MeSH Terms :
Alpha-Globulins/*pharmacology
Epithelial Cells/*pathology
Heme/*toxicity
Kidney Tubules, Proximal/*pathology
Protective Agents/*pharmacology
Apoptosis/drug effects ; Cell Line ; Cytoprotection/drug effects ; HSP70 Heat-Shock Proteins/metabolism ; Heme Oxygenase-1/genetics ; Heme Oxygenase-1/metabolism ; Humans ; Mitochondria/drug effects ; Mitochondria/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Recombinant Proteins/pharmacology ; Stress, Physiological/drug effects ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Structure-Redox Response Correlation in a Few Select Heme Systems Using X-ray Absorption Spectroelectrochemistry.
Autorzy :
Samajdar RN; Solid State and Structural Chemistry Unit, Indian Institute of Science, Bangalore 560012, India.
Bhattacharyya AJ; Solid State and Structural Chemistry Unit, Indian Institute of Science, Bangalore 560012, India.
Pokaż więcej
Źródło :
The journal of physical chemistry. B [J Phys Chem B] 2021 May 27; Vol. 125 (20), pp. 5258-5264. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Heme*/metabolism
Iron*
Oxidation-Reduction ; X-Ray Absorption Spectroscopy ; X-Rays
Czasopismo naukowe
Tytuł :
The Steady March toward Biomimetic Nanoelectronics.
Autorzy :
Rosso KM; Physical Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99354, United States.
Zarzycki P; Energy Geosciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, United States.
Pokaż więcej
Źródło :
ACS nano [ACS Nano] 2021 May 25; Vol. 15 (5), pp. 7844-7847. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Biomimetics*
Heme*/metabolism
Bacteria/metabolism ; Electron Transport ; Oxidation-Reduction
Czasopismo naukowe
Tytuł :
Activation of Nrf2/HO-1 by Peptide YD1 Attenuates Inflammatory Symptoms through Suppression of TLR4/MYyD88/NF-κB Signaling Cascade.
Autorzy :
Rahman MS; Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju 501-759, Korea.; Department of Food Science, Faculty of Agriculture and Food Sciences, Laval University, Québec, QC G1V 0A6, Canada.
Alam MB; Department of Food Science and Biotechnology, Kyungpook National University, Daegu 702-701, Korea.
Kim YK; Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju 501-759, Korea.
Madina MH; Department of Phytology, Faculty of Agriculture and Food Sciences, Laval University, Québec, QC G1V 0A6, Canada.
Fliss I; Department of Food Science, Faculty of Agriculture and Food Sciences, Laval University, Québec, QC G1V 0A6, Canada.
Lee SH; Department of Food Science and Biotechnology, Kyungpook National University, Daegu 702-701, Korea.
Yoo JC; Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju 501-759, Korea.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 13; Vol. 22 (10). Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Gene Expression Regulation/*drug effects
Heme Oxygenase-1/*metabolism
Inflammation/*prevention & control
Membrane Proteins/*metabolism
NF-E2-Related Factor 2/*metabolism
Pore Forming Cytotoxic Proteins/*pharmacology
Animals ; Cytokines/metabolism ; Edema/chemically induced ; Edema/metabolism ; Edema/pathology ; Edema/prevention & control ; Heme Oxygenase-1/genetics ; Inflammation/chemically induced ; Inflammation/metabolism ; Inflammation/pathology ; Lipopolysaccharides/toxicity ; Membrane Proteins/genetics ; Mice ; Myeloid Differentiation Factor 88/antagonists & inhibitors ; Myeloid Differentiation Factor 88/genetics ; Myeloid Differentiation Factor 88/metabolism ; NF-E2-Related Factor 2/genetics ; NF-kappa B/antagonists & inhibitors ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Nitric Oxide/metabolism ; Toll-Like Receptor 4/antagonists & inhibitors ; Toll-Like Receptor 4/genetics ; Toll-Like Receptor 4/metabolism
Czasopismo naukowe
Tytuł :
Implication of a Key Region of Six Bacillus cereus Genes Involved in Siroheme Synthesis, Nitrite Reductase Production and Iron Cluster Repair in the Bacterial Response to Nitric Oxide Stress.
Autorzy :
Porrini C; Micalis Institute, AgroParisTech, INRAE, Université Paris-Saclay, 78350 Jouy-en-Josas, France.
Guérin C; MaIAGE, INRAE, Université Paris-Saclay, 78350 Jouy-en-Josas, France.
Tran SL; Micalis Institute, AgroParisTech, INRAE, Université Paris-Saclay, 78350 Jouy-en-Josas, France.
Dervyn R; Micalis Institute, AgroParisTech, INRAE, Université Paris-Saclay, 78350 Jouy-en-Josas, France.
Nicolas P; MaIAGE, INRAE, Université Paris-Saclay, 78350 Jouy-en-Josas, France.
Ramarao N; Micalis Institute, AgroParisTech, INRAE, Université Paris-Saclay, 78350 Jouy-en-Josas, France.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 11; Vol. 22 (10). Date of Electronic Publication: 2021 May 11.
Typ publikacji :
Journal Article
MeSH Terms :
Oxidative Stress*
Bacillus cereus/*metabolism
Bacterial Proteins/*metabolism
Heme/*analogs & derivatives
Iron/*metabolism
Nitric Oxide/*toxicity
Nitrite Reductases/*metabolism
Bacillus cereus/drug effects ; Bacillus cereus/genetics ; Bacillus cereus/growth & development ; Bacterial Proteins/genetics ; Gene Expression Regulation, Bacterial ; Heme/biosynthesis ; Transcription, Genetic
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies