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Tytuł :
Triglyceride/HDL-cholesterol ratio and plasminogen activator inhibitor-1 independently predict high pulse pressure in sickle cell trait and disease.
Autorzy :
Olabode OP; HOPE Cardiometabolic Research Team, College of Health Sciences, University of Ilorin, Ilorin, Nigeria.; Department of Physiology, College of Health Sciences, University of Ilorin, Ilorin, Nigeria.
Akinlade OM; Department of Physiology, College of Health Sciences, University of Ilorin, Ilorin, Nigeria.; Department of Medicine, Ladoke Akintola University of Technology Teaching Hospital, Ogbomoso, Nigeria.
Babatunde AS; Department of Haematology and Blood Transfusion, College of Health Sciences, University of Ilorin, Nigeria.
Abdulazeez MI; Department of Chemical Pathology and Immunology, University of Ilorin Teaching Hospital, Ilorin, Nigeria.
Biliaminu SA; Department of Chemical Pathology and Immunology, University of Ilorin Teaching Hospital, Ilorin, Nigeria.
Oyabambi AO; HOPE Cardiometabolic Research Team, College of Health Sciences, University of Ilorin, Ilorin, Nigeria.; Department of Physiology, College of Health Sciences, University of Ilorin, Ilorin, Nigeria.
Olatunji VA; HOPE Cardiometabolic Research Team, College of Health Sciences, University of Ilorin, Ilorin, Nigeria.; Department of Ophthalmology, University of Ilorin Teaching Hospital, Ilorin, Nigeria.
Soladoye AO; Department of Physiology, College of Health Sciences, University of Ilorin, Ilorin, Nigeria.
Olatunji LA; HOPE Cardiometabolic Research Team, College of Health Sciences, University of Ilorin, Ilorin, Nigeria.; Department of Physiology, College of Health Sciences, University of Ilorin, Ilorin, Nigeria.
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Źródło :
Archives of physiology and biochemistry [Arch Physiol Biochem] 2020 May; Vol. 126 (2), pp. 166-171. Date of Electronic Publication: 2018 Aug 25.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Pressure*
Cholesterol, HDL/*blood
Hemoglobin SC Disease/*diagnosis
Plasminogen Activator Inhibitor 1/*blood
Sickle Cell Trait/*diagnosis
Triglycerides/*blood
Adolescent ; Adult ; Biomarkers/blood ; Female ; Hemoglobin A/metabolism ; Hemoglobin SC Disease/blood ; Hemoglobin, Sickle/metabolism ; Humans ; Linear Models ; Male ; ROC Curve ; Sickle Cell Trait/blood
Czasopismo naukowe
Tytuł :
Validation of the Siggaard-Andersen Acid-Base Nomogram for Hemoglobin F: Implications for Fetal Cord Blood Gas Analysis.
Autorzy :
Whitham M; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Pagaduan J; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Clark SL; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Singh I; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Belfort M; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Devaraj S; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Cao J; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Shetty A; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Pai S; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Fox K; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
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Źródło :
American journal of perinatology [Am J Perinatol] 2019 Dec; Vol. 36 (14), pp. 1481-1484. Date of Electronic Publication: 2019 Jan 23.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Blood Gas Analysis*
Fetal Hemoglobin*
Nomograms*
Bicarbonates/*blood
Fetal Blood/*chemistry
Acid-Base Equilibrium ; Acid-Base Imbalance ; Adult ; Female ; Hemoglobin A ; Humans ; Hydrogen-Ion Concentration ; Pregnancy ; Prospective Studies
Czasopismo naukowe
Tytuł :
Association between haematological parameters and sickle cell genotypes in children with Plasmodium falciparum malaria resident in Kisumu County in Western Kenya.
Autorzy :
Kosiyo P; Department of Biomedical Science and Technology, School of Pub;ic Health and Community Development, Maseno University, Maseno, Kenya.; Department of Medical Laboratory Sciences, School of Medicine, Kisii University, P.O. Box 408-40200, Kisii, Kenya.
Otieno W; Department of Paediatrics and Child Health, School of Medicine, Maseno University, Private Bag, Maseno, Kenya.
Gitaka J; School of Clinical Medicine, Mount Kenya University, Gen Kago Rd, P.O. Box 342 01000, Thika, Kenya.
Munde EO; Department of Clinical Medicine, School of Health Sciences, Kirinyaga University, P.O Box 143-10300, Kerugoya, Kenya.
Ouma C; Department of Biomedical Science and Technology, School of Pub;ic Health and Community Development, Maseno University, Maseno, Kenya. .
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2020 Nov 25; Vol. 20 (1), pp. 887. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :
Journal Article
MeSH Terms :
Genotype*
Anemia, Sickle Cell/*blood
Anemia, Sickle Cell/*epidemiology
Hemoglobin A/*genetics
Hemoglobin, Sickle/*genetics
Malaria, Falciparum/*epidemiology
Plasmodium falciparum/*isolation & purification
Adolescent ; Anemia, Sickle Cell/genetics ; Child ; Child, Preschool ; Comorbidity ; Cross-Sectional Studies ; Erythrocyte Count ; Erythrocyte Indices ; Female ; Hematocrit ; Hemoglobin A/analysis ; Hemoglobin, Sickle/analysis ; Humans ; Infant ; Kenya/epidemiology ; Leukocytosis ; Malaria, Falciparum/parasitology ; Male
Czasopismo naukowe
Tytuł :
Allosteric control of hemoglobin S fiber formation by oxygen and its relation to the pathophysiology of sickle cell disease.
Autorzy :
Henry ER; Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0520; .
Cellmer T; Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0520.
Dunkelberger EB; Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0520.
Metaferia B; Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0520.
Hofrichter J; Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0520.
Li Q; Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0520.
Ostrowski D; Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0520.
Ghirlando R; Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0520.
Louis JM; Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0520.
Moutereau S; Department of Genetics, Hôpital Henri Mondor, Assistance Publique-Hôpitaux de Paris, Université Paris-Est Créteil, 94010 Créteil, France.; IMRB Team 2, GRex, 94010 Créteil, France.
Galactéros F; IMRB Team 2, GRex, 94010 Créteil, France.; Sickle Cell Referral Center, Hôpital Henri Mondor, Assistance Publique-Hôpitaux de Paris, Université Paris-Est Créteil, 94010 Créteil, France.
Thein SL; Sickle Cell Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892.
Bartolucci P; IMRB Team 2, GRex, 94010 Créteil, France.; Sickle Cell Referral Center, Hôpital Henri Mondor, Assistance Publique-Hôpitaux de Paris, Université Paris-Est Créteil, 94010 Créteil, France.
Eaton WA; Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0520; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jun 30; Vol. 117 (26), pp. 15018-15027. Date of Electronic Publication: 2020 Jun 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
Anemia, Sickle Cell/*metabolism
Hemoglobin, Sickle/*chemistry
Oxygen/*metabolism
Allosteric Regulation ; Erythrocytes/chemistry ; Erythrocytes/metabolism ; Fetal Hemoglobin/chemistry ; Fetal Hemoglobin/metabolism ; Hemoglobin, Sickle/metabolism ; Humans ; Kinetics ; Oxygen/chemistry
Czasopismo naukowe
Tytuł :
The First Korean Family with Hemoglobin-M Milwaukee-2 Leading to Hereditary Methemoglobinemia.
Autorzy :
Kim DS; Department of Pediatrics, Chonnam National University Hwasun Hospital, Hwasun, Korea.
Baek HJ; Department of Pediatrics, Chonnam National University Hwasun Hospital, Hwasun, Korea.; Department of Pediatrics, Chonnam National University Medical School, Gwangju, Korea. .
Kim BR; Department of Pediatrics, Chonnam National University Hwasun Hospital, Hwasun, Korea.
Yoon BA; Department of Pediatrics, Chonnam National University Hwasun Hospital, Hwasun, Korea.; Department of Pediatrics, Chonnam National University Medical School, Gwangju, Korea.
Lee JH; Department of Laboratory Medicine, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Gwangju, Korea.
Kook H; Department of Pediatrics, Chonnam National University Hwasun Hospital, Hwasun, Korea.; Department of Pediatrics, Chonnam National University Medical School, Gwangju, Korea.
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Źródło :
Yonsei medical journal [Yonsei Med J] 2020 Dec; Vol. 61 (12), pp. 1064-1067.
Typ publikacji :
Case Reports
MeSH Terms :
Hemoglobin M*/genetics
Cyanosis/*etiology
Globins/*genetics
Methemoglobinemia/*congenital
Adolescent ; Child ; Cyanosis/genetics ; Female ; Globins/chemistry ; Hemoglobins, Abnormal/genetics ; Humans ; Male ; Methemoglobin/analysis ; Methemoglobin/genetics ; Methemoglobinemia/diagnosis ; Methemoglobinemia/genetics ; Point Mutation ; Republic of Korea ; Sequence Analysis, DNA
SCR Disease Name :
Congenital Methemoglobinemia; Hemoglobin M Disease
Raport
Tytuł :
Control of fetal globin expression in man: new opportunities to challenge past discoveries.
Autorzy :
Papayannopoulou T; Division of Hematology, Department of Medicine, University of Washington, Seattle, WA. Electronic address: .
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Źródło :
Experimental hematology [Exp Hematol] 2020 Dec; Vol. 92, pp. 43-50. Date of Electronic Publication: 2020 Oct 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Fetal Hemoglobin*/biosynthesis
Fetal Hemoglobin*/genetics
Silencer Elements, Transcriptional*
Adult ; Humans
Czasopismo naukowe
Tytuł :
A hypothesis about the role of fetal hemoglobin in COVID-19.
Autorzy :
Sotoudeh E; Department of Surgery, Red Crescent Hospital in Dubai, Al Wasl Rd, Dubai, United Arab Emirates.
Sotoudeh H; Department of Radiology and Neurology, University of Alabama at Birmingham (UAB), 619 19th St S, Birmingham, AL 35294, United States. Electronic address: .
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Źródło :
Medical hypotheses [Med Hypotheses] 2020 Nov; Vol. 144, pp. 109994. Date of Electronic Publication: 2020 Jun 12.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19/*blood
COVID-19/*drug therapy
Fetal Hemoglobin/*physiology
Adult ; Aging/blood ; COVID-19/mortality ; Child ; Fetal Hemoglobin/biosynthesis ; Fetal Hemoglobin/genetics ; Hemoglobinopathies/blood ; Hemoglobinopathies/drug therapy ; Hemoglobinopathies/epidemiology ; Humans ; Prevalence ; Severity of Illness Index ; Up-Regulation/drug effects
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Impact of a paediatric-adult care transition programme on the health status of patients with sickle cell disease: study protocol for a randomised controlled trial (the DREPADO trial).
Autorzy :
Hoegy D; EA 4129 P2S Parcours Santé Systémique-Université Claude Bernard Lyon 1, Université Lyon 1, Lyon, France. .; Pharmacie Hôpital Edouard Herriot, Hospices Civils de Lyon, 5 place d'Arsonval, 69003, Lyon, France. .; Institut des Sciences Pharmaceutiques et Biologiques, Université Claude Bernard Lyon 1, Université Lyon 1, Lyon, France. .; INSERM U1111-CNRS UMR 5308 ENS Lyon, Université Lyon 1, Lyon, France. .
Bleyzac N; EMR 3738, PK/PD modeling in oncology, Université Claude Bernard Lyon 1, Université Lyon 1, Lyon, France.; Centre Antipoison, Hospices Civils de Lyon, Lyon, France.
Gauthier-Vasserot A; INSERM U1111-CNRS UMR 5308 ENS Lyon, Université Lyon 1, Lyon, France.; Institut d'Hématologie et d'Oncologie Pédiatrique de Lyon, Hospices Civils de Lyon, Lyon, France.; Laboratoire Interuniversitaire de Biologie de la Motricité (LIBM) EA7424, Université Claude Bernard Lyon 1, Université Lyon 1, Lyon, France.; Laboratoire d'Excellence du Globule Rouge (Labex GR-Ex), PRES Sorbonne, Paris, France.
Cannas G; INSERM U1111-CNRS UMR 5308 ENS Lyon, Université Lyon 1, Lyon, France.; Laboratoire Interuniversitaire de Biologie de la Motricité (LIBM) EA7424, Université Claude Bernard Lyon 1, Université Lyon 1, Lyon, France.; Laboratoire d'Excellence du Globule Rouge (Labex GR-Ex), PRES Sorbonne, Paris, France.; Médecine Interne, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France.
Denis A; Pôle Santé Publique, Hospices Civils de Lyon, Lyon, France.
Hot A; Médecine Interne, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France.; Centre de Référence Constitutif Syndromes Drépanocytaires Majeurs, Thalassémies et Autres Pathologies Rares du Globule Rouge et de l'Erythropoïèse, Hospices Civils de Lyon, Lyon, France.
Bertrand Y; INSERM U1111-CNRS UMR 5308 ENS Lyon, Université Lyon 1, Lyon, France.; Institut d'Hématologie et d'Oncologie Pédiatrique de Lyon, Hospices Civils de Lyon, Lyon, France.; Centre de Référence Constitutif Syndromes Drépanocytaires Majeurs, Thalassémies et Autres Pathologies Rares du Globule Rouge et de l'Erythropoïèse, Hospices Civils de Lyon, Lyon, France.
Occelli P; Pôle Santé Publique, Hospices Civils de Lyon, Lyon, France.; EA 7425 HESPER Health Services and Performance Research, Université Lyon 1, Lyon, France.
Touzet S; Pôle Santé Publique, Hospices Civils de Lyon, Lyon, France.; EA 7425 HESPER Health Services and Performance Research, Université Lyon 1, Lyon, France.
Dussart C; EA 4129 P2S Parcours Santé Systémique-Université Claude Bernard Lyon 1, Université Lyon 1, Lyon, France.; Pharmacie Centrale, Hospices Civils de Lyon, Lyon, France.
Janoly-Dumenil A; EA 4129 P2S Parcours Santé Systémique-Université Claude Bernard Lyon 1, Université Lyon 1, Lyon, France.; Pharmacie Hôpital Edouard Herriot, Hospices Civils de Lyon, 5 place d'Arsonval, 69003, Lyon, France.; Institut des Sciences Pharmaceutiques et Biologiques, Université Claude Bernard Lyon 1, Université Lyon 1, Lyon, France.
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Corporate Authors :
DREPADO study group
Źródło :
Trials [Trials] 2020 Feb 10; Vol. 21 (1), pp. 152. Date of Electronic Publication: 2020 Feb 10.
Typ publikacji :
Clinical Trial Protocol; Journal Article
MeSH Terms :
Health Status*
Transition to Adult Care*
Hemoglobin SC Disease/*physiopathology
Hemoglobin SC Disease/*psychology
Adaptation, Psychological ; Adolescent ; Awareness ; Emotions ; Female ; Hemoglobin SC Disease/blood ; Hemoglobin, Sickle ; Humans ; Male ; Multicenter Studies as Topic ; Pain Management ; Patient Readmission ; Quality of Life ; Randomized Controlled Trials as Topic ; Self Care ; Self Efficacy
Czasopismo naukowe
Tytuł :
Two Decades of Gla-100-Reflections from the Pivotal Clinical Trials.
Autorzy :
Makkar BM; Senior Consultant Endocrinologist, Dr. Makkar's diabetes and obesity center, Delhi.
Sinha AK; Associate Professor, Department of Medicine, NMCH, Patna, Bihar.
Suryanarayana KM; Senior Consultant, Department of Endocrinology, MS Ramaiah Memorial Hospital, Bangalore, Karnataka.
Chakravorty S; Senior Consultant, Metro Hospital, Delhi.
Sidduri SR; Senior Consultant Endocrinologist, Sreenidhi Diabetes Thyroid Endocrine Hospital, Karimnagar, Telangana.
Ahmad A; Consultant Endocrinologist, Moulana Hospital, Malappuram, Kerala.
Biswas K; Consultant Endocrinologist, Medica Superspeciality Hospital, Kolkata, West Bengal.
Roy A; Medical Affairs, Diabetes and Cardiovascular, Sanofi India Ltd.
Mohan V; Chairman and Chief Diabetologist, Dr. Mohan's Diabetes Specialities Centre, Chennai, Tamil Nadu.
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Źródło :
The Journal of the Association of Physicians of India [J Assoc Physicians India] 2020 Dec; Vol. 68 (12[Special]), pp. 18-24.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*/drug therapy
Glycated Hemoglobin A*/analysis
Hypoglycemic Agents*/therapeutic use
Blood Glucose ; Clinical Trials as Topic ; Humans ; Insulin/therapeutic use ; Insulin Glargine ; Insulin, Long-Acting
Czasopismo naukowe
Tytuł :
Toward targeted prevention: risk factors for prediabetes defined by impaired fasting glucose, impaired glucose tolerance and increased HbA1c in the population-based KORA study from Germany.
Autorzy :
Greiner GG; Institute for Health Services Research and Health Economics, German Diabetes Center, Auf'm Hennekamp 65, 40225, Duesseldorf, Germany. .; Medical Faculty, Centre for Health and Society, Institute for Health Services Research and Health Economics, Heinrich Heine University, Moorenstr. 5, 40225, Duesseldorf, Germany. .; Institute of Health Economics and Health Care Management, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany. .
Emmert-Fees KMF; Institute of Health Economics and Health Care Management, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
Becker J; Institute of Health Economics and Health Care Management, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.; Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital Munich, Ludwig-Maximilians-University Munich, Ziemssenstr. 1, 80336, Munich, Germany.
Rathmann W; Institute for Biometry and Epidemiology, German Diabetes Center, Auf'm Hennekamp 65, 40225, Duesseldorf, Germany.; German Centre for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764, Munich-Neuherberg, Germany.
Thorand B; German Centre for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764, Munich-Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
Peters A; German Centre for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764, Munich-Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
Quante AS; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.; Department of Gynecology and Obstetrics, Klinikum Rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.
Schwettmann L; Institute of Health Economics and Health Care Management, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.; Department of Economics, Martin Luther University Halle-Wittenberg, 06099, Halle (Saale), Germany.
Laxy M; Institute of Health Economics and Health Care Management, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.; German Centre for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764, Munich-Neuherberg, Germany.; Global Diabetes Research Center, Rollins School of Public Health, Emory University, 1518 Clifton Rd., NE, Atlanta, GA, 30322, USA.
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Źródło :
Acta diabetologica [Acta Diabetol] 2020 Dec; Vol. 57 (12), pp. 1481-1491. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Diabetes Mellitus, Type 2/*prevention & control
Glucose Intolerance/*diagnosis
Glycated Hemoglobin A/*metabolism
Prediabetic State/*diagnosis
Prediabetic State/*epidemiology
Preventive Medicine/*trends
Adult ; Aged ; Blood Glucose/analysis ; Blood Glucose/metabolism ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/epidemiology ; Diabetes Mellitus, Type 2/etiology ; Fasting/blood ; Female ; Germany/epidemiology ; Glucose Intolerance/blood ; Glucose Intolerance/epidemiology ; Glucose Intolerance/etiology ; Glycated Hemoglobin A/analysis ; Health Services Needs and Demand/organization & administration ; Health Services Needs and Demand/trends ; Humans ; Male ; Middle Aged ; Prediabetic State/blood ; Prediabetic State/etiology ; Preventive Medicine/methods ; Risk Factors ; Socioeconomic Factors ; Young Adult
Czasopismo naukowe
Tytuł :
The trials and tribulations of determining HbA 1c targets for diabetes mellitus.
Autorzy :
Klein KR; Division of Endocrinology and Metabolism, University of North Carolina School of Medicine, Chapel Hill, NC, USA. .
Buse JB; Division of Endocrinology and Metabolism, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
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Źródło :
Nature reviews. Endocrinology [Nat Rev Endocrinol] 2020 Dec; Vol. 16 (12), pp. 717-730. Date of Electronic Publication: 2020 Oct 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Diabetes Mellitus/*metabolism
Glycated Hemoglobin A/*metabolism
Hypoglycemic Agents/*therapeutic use
Animals ; Diabetes Mellitus/blood ; Diabetes Mellitus/drug therapy ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 1/drug therapy ; Diabetes Mellitus, Type 1/metabolism ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/metabolism ; Glycated Hemoglobin A/analysis ; Goals ; Humans
Czasopismo naukowe
Tytuł :
Comprehensive screening for coexisting heterozygous α -thalassemia in hemoglobin E trait.
Autorzy :
Polprasert C; Faculty of Medicine, Department of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.; Faculty of Medicine, Research Unit in Translational Hematology, Chulalongkorn University, Bangkok, Thailand.
Wongprachar P; Faculty of Medicine, Department of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Suksusut A; Faculty of Medicine, Department of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Settapiboon R; Faculty of Medicine, Department of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Amornsirivat S; Faculty of Medicine, Department of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Sophonphan J; The HIV Netherlands Australia Thailand Research Collaboration (HIV-NAT), Bangkok, Thailand.
Uaprasert N; Faculty of Medicine, Department of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Sucharitchan P; Faculty of Medicine, Department of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Rojnuckarin P; Faculty of Medicine, Department of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.; Faculty of Medicine, Research Unit in Translational Hematology, Chulalongkorn University, Bangkok, Thailand.
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Źródło :
Hematology (Amsterdam, Netherlands) [Hematology] 2020 Dec; Vol. 25 (1), pp. 276-279.
Typ publikacji :
Journal Article
MeSH Terms :
Hemoglobin E/*genetics
alpha-Thalassemia/*genetics
Adult ; Aged ; Chromatography, High Pressure Liquid ; Female ; Hemoglobin E/analysis ; Heterozygote ; Humans ; Isoelectric Focusing ; Male ; Middle Aged ; Young Adult ; alpha-Thalassemia/blood
Czasopismo naukowe
Tytuł :
Assay for "fetal hemoglobin levels" in erythrocytes: Impact of new In Vitro Diagnostics regulation and expanded applications in sickle cell disease management.
Autorzy :
Davis BH; Department of Microbiology, University of Porto Faculty of Medicine, Porto, Portugal.
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Źródło :
American journal of hematology [Am J Hematol] 2020 Nov; Vol. 95 (11), pp. 1230-1232. Date of Electronic Publication: 2020 Sep 17.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Anemia, Sickle Cell*
Fetal Hemoglobin*
Erythrocytes ; Humans
Czasopismo naukowe
Tytuł :
UNC0638 induces high levels of fetal hemoglobin expression in β-thalassemia/HbE erythroid progenitor cells.
Autorzy :
Nualkaew T; Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, 25/25 Phuttamonthon 4 Road, Salaya, Nakhon Pathom, 73170, Thailand.
Khamphikham P; Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, 25/25 Phuttamonthon 4 Road, Salaya, Nakhon Pathom, 73170, Thailand.; Department of Forensic Science, Faculty of Allied Health Sciences, Thammasat University, Pathum Thani, Thailand.
Pongpaksupasin P; Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, 25/25 Phuttamonthon 4 Road, Salaya, Nakhon Pathom, 73170, Thailand.; Department of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Kaewsakulthong W; Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, 25/25 Phuttamonthon 4 Road, Salaya, Nakhon Pathom, 73170, Thailand.; Department of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Songdej D; Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Paiboonsukwong K; Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, 25/25 Phuttamonthon 4 Road, Salaya, Nakhon Pathom, 73170, Thailand.
Sripichai O; National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand.
Engel JD; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.
Hongeng S; Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Fucharoen S; Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, 25/25 Phuttamonthon 4 Road, Salaya, Nakhon Pathom, 73170, Thailand.
Jearawiriyapaisarn N; Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, 25/25 Phuttamonthon 4 Road, Salaya, Nakhon Pathom, 73170, Thailand. .
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Źródło :
Annals of hematology [Ann Hematol] 2020 Sep; Vol. 99 (9), pp. 2027-2036. Date of Electronic Publication: 2020 Jun 21.
Typ publikacji :
Journal Article
MeSH Terms :
Erythroid Precursor Cells/*metabolism
Fetal Hemoglobin/*biosynthesis
Hemoglobin E/*metabolism
Quinazolines/*pharmacology
beta-Thalassemia/*metabolism
Cell Proliferation/drug effects ; Cell Proliferation/physiology ; Cells, Cultured ; Dose-Response Relationship, Drug ; Erythroid Precursor Cells/drug effects ; Fetal Hemoglobin/genetics ; Gene Expression ; Humans ; beta-Thalassemia/genetics
Czasopismo naukowe
Tytuł :
Dominant β-thalassaemia with unusually high Hb A 2 and Hb F caused by β (HBB:c.364delG) in exon 3 of β-globin gene.
Autorzy :
Singha K; Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Muang, Khon Kaen, Thailand.
Karnpean R; College of Medicine and Public Health, Ubon Ratchathani University, Warinchamrap, Ubon Ratchathani, Thailand.
Fucharoen G; Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Muang, Khon Kaen, Thailand.
Fucharoen S; Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Muang, Khon Kaen, Thailand .
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Źródło :
Journal of clinical pathology [J Clin Pathol] 2020 Aug; Vol. 73 (8), pp. 511-513. Date of Electronic Publication: 2019 Dec 26.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Exons/*genetics
Fetal Hemoglobin/*metabolism
Hemoglobin A2/*metabolism
Sequence Deletion/*genetics
beta-Globins/*genetics
beta-Thalassemia/*genetics
Adult ; DNA/analysis ; Fetal Hemoglobin/genetics ; Frameshift Mutation/genetics ; Hemoglobin A2/genetics ; Heterozygote ; Humans ; Male ; Protein Structure, Secondary/genetics ; beta-Globins/chemistry
Czasopismo naukowe
Tytuł :
Abnormally Low Hemoglobin A1c as Harbinger of Hemoglobinopathy.
Autorzy :
St Louis J; From the Department of Family Medicine, Tufts University School of Medicine, Boston, MA (JSL); Department of Family Medicine, University of Massachusetts School of Medicine, Worcester, MA (AV). .
Valdini A; From the Department of Family Medicine, Tufts University School of Medicine, Boston, MA (JSL); Department of Family Medicine, University of Massachusetts School of Medicine, Worcester, MA (AV).
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Źródło :
Journal of the American Board of Family Medicine : JABFM [J Am Board Fam Med] 2019 Nov-Dec; Vol. 32 (6), pp. 923-924.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Anemia, Sickle Cell/*diagnosis
Glycated Hemoglobin A/*analysis
Adult ; Anemia, Sickle Cell/blood ; Anemia, Sickle Cell/genetics ; Asymptomatic Diseases ; Female ; Fetal Hemoglobin/analysis ; Hemoglobin, Sickle/genetics ; Homozygote ; Humans
Czasopismo naukowe
Tytuł :
A novel SNP rs11759328 on Rho GTPase-activating protein 18 gene is associated with the expression of Hb F in hemoglobin E-related disorders.
Autorzy :
Jomoui W; Department of Pathology, Maha Chakri Sirindhorn Medical Center, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok, Thailand. .
Tepakhan W; Department of Pathology, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
Yamsri S; Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.
Srivorakun H; Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.
Fucharoen G; Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.
Fucharoen S; Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.
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Źródło :
Annals of hematology [Ann Hematol] 2020 Jan; Vol. 99 (1), pp. 23-29. Date of Electronic Publication: 2019 Nov 27.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Gene Expression Regulation*
Mutation*
Polymorphism, Single Nucleotide*
Fetal Hemoglobin/*biosynthesis
GTPase-Activating Proteins/*genetics
Hemoglobinuria/*genetics
Fetal Hemoglobin/genetics ; GTPase-Activating Proteins/metabolism ; Hemoglobin E/genetics ; Hemoglobin E/metabolism ; Hemoglobinuria/blood ; Humans ; Kruppel-Like Transcription Factors/genetics ; Kruppel-Like Transcription Factors/metabolism ; Thailand
Czasopismo naukowe
Tytuł :
Sickle cell disease: A distinction of two most frequent genotypes (HbSS and HbSC).
Autorzy :
da Guarda CC; Laboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador, Bahia, Brasil.
Yahouédéhou SCMA; Laboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador, Bahia, Brasil.
Santiago RP; Laboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador, Bahia, Brasil.
Neres JSDS; Laboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador, Bahia, Brasil.
Fernandes CFL; Laboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador, Bahia, Brasil.
Aleluia MM; Departamento de Ciências Biológicas, Universidade Estadual de Santa Cruz, UESC, Bahia, Brasil.
Figueiredo CVB; Laboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador, Bahia, Brasil.
Fiuza LM; Laboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador, Bahia, Brasil.
Carvalho SP; Laboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador, Bahia, Brasil.
Oliveira RM; Laboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador, Bahia, Brasil.
Fonseca CA; Laboratório de Pesquisa em Anemias, Departamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal da Bahia, Salvador, Bahia, Brasil.
Ndidi US; Laboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador, Bahia, Brasil.
Nascimento VML; Fundação de Hematologia e Hemoterapia do Estado da Bahia, HEMOBA, Salvador, Bahia, Brasil.
Rocha LC; Fundação de Hematologia e Hemoterapia do Estado da Bahia, HEMOBA, Salvador, Bahia, Brasil.
Goncalves MS; Laboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador, Bahia, Brasil.
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Źródło :
PloS one [PLoS One] 2020 Jan 29; Vol. 15 (1), pp. e0228399. Date of Electronic Publication: 2020 Jan 29 (Print Publication: 2020).
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anemia, Sickle Cell/*metabolism
Biomarkers/*analysis
Hemoglobin, Sickle/*genetics
Adolescent ; Anemia, Sickle Cell/drug therapy ; Anemia, Sickle Cell/genetics ; Child ; Cross-Sectional Studies ; Female ; Folic Acid/therapeutic use ; Genotype ; Hemoglobin SC Disease/drug therapy ; Hemoglobin SC Disease/genetics ; Hemoglobin SC Disease/metabolism ; Humans ; Hydroxyurea/therapeutic use ; Male
Czasopismo naukowe
Tytuł :
Hemoglobins F, A 2 , and E levels in Laotian children aged 6-23 months with Hb E disorders: Effect of age, sex, and thalassemia types.
Autorzy :
Kingchaiyaphum B; Graduate School, Khon Kaen University, Khon Kaen, Thailand.
Sanchaisuriya K; Center for Research and Development of Medical Diagnostic Laboratories (CMDL), Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.
Fucharoen G; Center for Research and Development of Medical Diagnostic Laboratories (CMDL), Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.
Chaibunruang A; Center for Research and Development of Medical Diagnostic Laboratories (CMDL), Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.
Hess SY; Institute for Global Nutrition, University of California, Davis, CA, USA.
Hinnouho GM; Institute for Global Nutrition, University of California, Davis, CA, USA.
Barffour MA; Institute for Global Nutrition, University of California, Davis, CA, USA.
Wessells KR; Institute for Global Nutrition, University of California, Davis, CA, USA.
Kounnavong S; Lao Tropical and Public Health Institute, Ministry of Health, Vientiane, Lao.
Fucharoen S; Center for Research and Development of Medical Diagnostic Laboratories (CMDL), Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.
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Źródło :
International journal of laboratory hematology [Int J Lab Hematol] 2020 Jun; Vol. 42 (3), pp. 277-283. Date of Electronic Publication: 2020 Feb 12.
Typ publikacji :
Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms :
Fetal Hemoglobin*/genetics
Fetal Hemoglobin*/metabolism
Hemoglobin A2*/genetics
Hemoglobin A2*/metabolism
Hemoglobin E*/genetics
Hemoglobin E*/metabolism
Heterozygote*
Homozygote*
alpha-Thalassemia*/blood
alpha-Thalassemia*/genetics
Age Factors ; Female ; Humans ; Infant ; Laos ; Male ; Sex Factors
Czasopismo naukowe
Tytuł :
Significance of heme oxygenase-1(HMOX1) gene on fetal hemoglobin induction in sickle cell anemia patients.
Autorzy :
Hariharan P; Department of Haematogenetics, ICMR-National Institute of Immunohaematology, 13th floor NMS Building, KEM Hospital Campus, Parel, Mumbai, 400012, Maharashtra, India.
Chavan V; Department of Haematogenetics, ICMR-National Institute of Immunohaematology, 13th floor NMS Building, KEM Hospital Campus, Parel, Mumbai, 400012, Maharashtra, India.
Nadkarni A; Department of Haematogenetics, ICMR-National Institute of Immunohaematology, 13th floor NMS Building, KEM Hospital Campus, Parel, Mumbai, 400012, Maharashtra, India. .
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Źródło :
Scientific reports [Sci Rep] 2020 Oct 28; Vol. 10 (1), pp. 18506. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fetal Hemoglobin/*genetics
Heme Oxygenase-1/*genetics
Heme Oxygenase-1/*metabolism
Adolescent ; Adult ; Alleles ; Anemia, Sickle Cell/metabolism ; Anemia, Sickle Cell/physiopathology ; Child ; Child, Preschool ; Female ; Fetal Hemoglobin/analysis ; Gene Frequency/genetics ; Genotype ; Heme Oxygenase-1/physiology ; Humans ; Infant ; Male ; Middle Aged ; Polymorphism, Restriction Fragment Length/genetics ; Polymorphism, Single Nucleotide/genetics ; Sequence Analysis, DNA/methods
Czasopismo naukowe

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