Temat: "human immunodeficiency virus" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Modeling and Analysis of HIV-1 Pol Polyprotein as a Case Study for Predicting Large Polyprotein Structures.
Autorzy:: Hao M; Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Imamichi T; Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Chang W; Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 02; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:: Journal Article
MeSH Terms:: HIV Infections*/drug therapy
HIV-1*/genetics
HIV-1*/metabolism
pol Gene Products, Human Immunodeficiency Virus*/chemistry
Humans ; Gene Products, pol/genetics ; Gene Products, pol/metabolism ; HIV Protease/genetics ; HIV Protease/metabolism ; Polyproteins/genetics ; RNA-Directed DNA Polymerase/metabolism

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Skocz do pozycji: 2.

Tytuł:: HIV-1 Tat Induces Dysregulation of PGC1-Alpha and Sirtuin 3 Expression in Neurons: The Role of Mitochondrial Biogenesis in HIV-Associated Neurocognitive Disorder (HAND).
Autorzy:: Figarola-Centurión I; Doctorado en Genética Humana, Departamento de Biología Molecular y Genómica, Universidad de Guadalajara, Guadalajara 44340, Mexico.; Laboratorio de Inmunodeficiencias y Retrovirus Humanos, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara 44340, Mexico.
Escoto-Delgadillo M; Laboratorio de Inmunodeficiencias y Retrovirus Humanos, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara 44340, Mexico.; Centro Universitario de Ciencias Biológicas y Agropecuarias, Universidad de Guadalajara, Guadalajara 44600, Mexico.
González-Enríquez GV; Departamento de Disciplinas Filosófico, Metodológicas e Instrumentales, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Gutiérrez-Sevilla JE; Laboratorio de Inmunodeficiencias y Retrovirus Humanos, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara 44340, Mexico.; Doctorado en Microbiología Médica, Departamento de Microbiología y Patología, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Vázquez-Valls E; Investigación y Calidad de Salud, Secretaría de Salud, Guadalajara 44100, Mexico.
Cárdenas-Bedoya J; Laboratorio de Inmunodeficiencias y Retrovirus Humanos, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara 44340, Mexico.; Departamento de Disciplinas Filosófico, Metodológicas e Instrumentales, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Torres-Mendoza BM; Laboratorio de Inmunodeficiencias y Retrovirus Humanos, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara 44340, Mexico.; Departamento de Disciplinas Filosófico, Metodológicas e Instrumentales, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 17; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 17.
Typ publikacji:: Journal Article
MeSH Terms:: HIV Infections*/metabolism
HIV-1*/metabolism
Neurocognitive Disorders*/metabolism
Neurocognitive Disorders*/virology
Sirtuin 3*/genetics
Sirtuin 3*/metabolism
tat Gene Products, Human Immunodeficiency Virus*/genetics
tat Gene Products, Human Immunodeficiency Virus*/metabolism
Animals ; Rats ; Gene Products, tat/metabolism ; Neurons/metabolism ; Organelle Biogenesis ; Protein Kinases/metabolism ; Rats, Sprague-Dawley ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha

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Skocz do pozycji: 3.

Tytuł:: TAT peptide at treatment-level concentrations crossed brain endothelial cell monolayer independent of receptor-mediated endocytosis or peptide-inflicted barrier disruption.
Autorzy:: Wu MC; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan.
Wang EY; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.; School of Medicine, China Medical University, Taichung, Taiwan.
Lai TW; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.; School of Medicine, China Medical University, Taichung, Taiwan.; Neuroscience and Brain Disease Center, China Medical University, Taichung, Taiwan.; Drug Development Center, China Medical University, Taichung, Taiwan.; Translational Medicine Research Center, China Medical University Hospital, Taichung, Taiwan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Oct 11; Vol. 18 (10), pp. e0292681. Date of Electronic Publication: 2023 Oct 11 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Endothelial Cells*/metabolism
tat Gene Products, Human Immunodeficiency Virus*/metabolism
Brain/metabolism ; Blood-Brain Barrier/metabolism ; Peptides/metabolism ; Endocytosis

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Skocz do pozycji: 4.

Tytuł:: HIV-1 Transcriptional Activator Tat Inhibits IL2 Expression by Preventing the Presence of Pol II on the IL2 Promoter.
Autorzy:: Anastasopoulou S; Laboratory of Immunohematology, Division of Hematology, Department of Internal Medicine, Medical School, University of Patras, GR-26500 Patras, Greece.
Georgakopoulos T; Laboratory of Immunohematology, Division of Hematology, Department of Internal Medicine, Medical School, University of Patras, GR-26500 Patras, Greece.
Mouzaki A; Laboratory of Immunohematology, Division of Hematology, Department of Internal Medicine, Medical School, University of Patras, GR-26500 Patras, Greece.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2023 May 24; Vol. 13 (6). Date of Electronic Publication: 2023 May 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: HIV Infections*/genetics
HIV Infections*/immunology
HIV Infections*/virology
HIV-1*/genetics
HIV-1*/metabolism
Interleukin-2*/genetics
Interleukin-2*/metabolism
RNA Polymerase II*/genetics
RNA Polymerase II*/metabolism
tat Gene Products, Human Immunodeficiency Virus*/genetics
tat Gene Products, Human Immunodeficiency Virus*/metabolism
Humans ; Gene Expression Regulation, Viral ; Transcription Factors/metabolism ; Transcription, Genetic ; Transcriptional Activation

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Skocz do pozycji: 5.

Tytuł:: A Novel Time-Resolved Fluorescence Resonance Energy Transfer Assay for the Discovery of Small-Molecule Inhibitors of HIV-1 Tat-Regulated Transcription.
Autorzy:: Shin YH; Division of Chronic Viral Diseases, Center for Emerging Virus Research, Korea National Institute of Health, 187 Osongsaengmyeong 2-ro, Cheongju 363951, Republic of Korea.
Kim DE; Division of Chronic Viral Diseases, Center for Emerging Virus Research, Korea National Institute of Health, 187 Osongsaengmyeong 2-ro, Cheongju 363951, Republic of Korea.
Yu KL; Division of Chronic Viral Diseases, Center for Emerging Virus Research, Korea National Institute of Health, 187 Osongsaengmyeong 2-ro, Cheongju 363951, Republic of Korea.
Park CM; Department for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Daejeon 34114, Republic of Korea.
Kim HG; Department for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Daejeon 34114, Republic of Korea.
Kim KC; Division of Chronic Viral Diseases, Center for Emerging Virus Research, Korea National Institute of Health, 187 Osongsaengmyeong 2-ro, Cheongju 363951, Republic of Korea.
Bae S; Division of Chronic Viral Diseases, Center for Emerging Virus Research, Korea National Institute of Health, 187 Osongsaengmyeong 2-ro, Cheongju 363951, Republic of Korea.
Yoon CH; Division of Chronic Viral Diseases, Center for Emerging Virus Research, Korea National Institute of Health, 187 Osongsaengmyeong 2-ro, Cheongju 363951, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 May 23; Vol. 24 (11). Date of Electronic Publication: 2023 May 23.
Typ publikacji:: Journal Article
MeSH Terms:: tat Gene Products, Human Immunodeficiency Virus*/genetics
tat Gene Products, Human Immunodeficiency Virus*/chemistry
HIV-1*/physiology
Humans ; Fluorescence Resonance Energy Transfer ; Trans-Activators ; RNA, Viral/genetics

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Skocz do pozycji: 6.

Tytuł:: Bioinformatics Insights on Viral Gene Expression Transactivation: From HIV-1 to SARS-CoV-2.
Autorzy:: Patarca R; ACCESS Health International, 384 West Lane, Ridgefield, CT 06877, USA.; Feinstein Institutes for Medical Research, 350 Community Dr, Manhasset, NY 11030, USA.
Haseltine WA; ACCESS Health International, 384 West Lane, Ridgefield, CT 06877, USA.; Feinstein Institutes for Medical Research, 350 Community Dr, Manhasset, NY 11030, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 16; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 16.
Typ publikacji:: Journal Article
MeSH Terms:: HIV-1*/physiology
COVID-19*/genetics
Humans ; SARS-CoV-2/genetics ; SARS-CoV-2/metabolism ; Transcriptional Activation ; HIV Long Terminal Repeat ; Gene Products, tat/genetics ; Lentivirus/genetics ; Gene Expression ; tat Gene Products, Human Immunodeficiency Virus/genetics ; tat Gene Products, Human Immunodeficiency Virus/metabolism ; RNA, Viral/metabolism

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Skocz do pozycji: 7.

Tytuł:: HIV-1 Vpr Functions in Primary CD4 T Cells.
Autorzy:: Vanegas-Torres CA; Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, 72076 Tuebingen, Germany.
Schindler M; Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, 72076 Tuebingen, Germany.; Pokaż więcej
Źródło:: Viruses [Viruses] 2024 Mar 09; Vol. 16 (3). Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:: Journal Article; Review
MeSH Terms:: HIV-1*/genetics
HIV Seropositivity*
HIV Infections*/metabolism
Humans ; T-Lymphocytes/metabolism ; vpr Gene Products, Human Immunodeficiency Virus/genetics ; vpr Gene Products, Human Immunodeficiency Virus/metabolism ; CD4-Positive T-Lymphocytes/metabolism

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Skocz do pozycji: 8.

Tytuł:: Maturation of the matrix and viral membrane of HIV-1.
Autorzy:: Qu K; Molecular Medicine Partnership Unit, European Molecular Biology Laboratory and Universitätsklinikum Heidelberg, 69117 Heidelberg, Germany.; Structural Studies Division, Medical Research Council Laboratory of Molecular Biology, CB2 0QH Cambridge, UK.; Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.; Molecular Medicine Partnership Unit, European Molecular Biology Laboratory and Universitätsklinikum Heidelberg, 69117 Heidelberg, Germany.
Ke Z; Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, 69120 Heidelberg, Germany.; Structural Studies Division, Medical Research Council Laboratory of Molecular Biology, CB2 0QH Cambridge, UK.
Zila V; Structural Studies Division, Medical Research Council Laboratory of Molecular Biology, CB2 0QH Cambridge, UK.; Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, 69120 Heidelberg, Germany.
Anders-Össwein M; Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, 69120 Heidelberg, Germany.
Glass B; Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.; Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, 69120 Heidelberg, Germany.
Mücksch F; Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, 69120 Heidelberg, Germany.
Müller R; Molecular Medicine Partnership Unit, European Molecular Biology Laboratory and Universitätsklinikum Heidelberg, 69117 Heidelberg, Germany.; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.
Schultz C; Molecular Medicine Partnership Unit, European Molecular Biology Laboratory and Universitätsklinikum Heidelberg, 69117 Heidelberg, Germany.; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.; Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, OR 97239, USA.
Müller B; Structural Studies Division, Medical Research Council Laboratory of Molecular Biology, CB2 0QH Cambridge, UK.; Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.; Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, 69120 Heidelberg, Germany.
Kräusslich HG; Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, 69120 Heidelberg, Germany.; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.; Structural Studies Division, Medical Research Council Laboratory of Molecular Biology, CB2 0QH Cambridge, UK.; Molecular Medicine Partnership Unit, European Molecular Biology Laboratory and Universitätsklinikum Heidelberg, 69117 Heidelberg, Germany.; Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, 69120 Heidelberg, Germany.; German Center for Infection Research, Heidelberg, Germany.
Briggs JAG; Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, 69120 Heidelberg, Germany. .; Molecular Medicine Partnership Unit, European Molecular Biology Laboratory and Universitätsklinikum Heidelberg, 69117 Heidelberg, Germany.; Structural Studies Division, Medical Research Council Laboratory of Molecular Biology, CB2 0QH Cambridge, UK.; Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.; Molecular Medicine Partnership Unit, European Molecular Biology Laboratory and Universitätsklinikum Heidelberg, 69117 Heidelberg, Germany.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2021 Aug 06; Vol. 373 (6555), pp. 700-704.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: HIV Antigens/*chemistry
HIV Antigens/*metabolism
HIV-1/*chemistry
HIV-1/*physiology
Viral Envelope/*metabolism
gag Gene Products, Human Immunodeficiency Virus/*chemistry
gag Gene Products, Human Immunodeficiency Virus/*metabolism
Capsid/chemistry ; Capsid/physiology ; Electron Microscope Tomography ; HIV-1/ultrastructure ; Lipid Bilayers ; Membrane Lipids/metabolism ; Models, Molecular ; Protein Conformation ; Protein Domains ; Protein Structure, Secondary ; Viral Envelope/chemistry ; Viral Envelope/ultrastructure ; Virion/chemistry ; Virion/physiology ; Virion/ultrastructure ; Virus Assembly ; env Gene Products, Human Immunodeficiency Virus/chemistry ; env Gene Products, Human Immunodeficiency Virus/metabolism

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Skocz do pozycji: 9.

Tytuł:: Beyond Impairment of Virion Infectivity: New Activities of the Anti-HIV Host Cell Factor SERINC5.
Autorzy:: Sid Ahmed S; Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, Im Neuenheimer Feld 344, 69120 Heidelberg, Germany.
Bajak K; Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, Im Neuenheimer Feld 344, 69120 Heidelberg, Germany.; German Centre for Infection Research (DZIF), Partner Site Heidelberg, 38124 Heidelberg, Germany.
Fackler OT; Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, Im Neuenheimer Feld 344, 69120 Heidelberg, Germany.; German Centre for Infection Research (DZIF), Partner Site Heidelberg, 38124 Heidelberg, Germany.; Pokaż więcej
Źródło:: Viruses [Viruses] 2024 Feb 12; Vol. 16 (2). Date of Electronic Publication: 2024 Feb 12.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Membrane Proteins*/metabolism
HIV Infections*
Humans ; nef Gene Products, Human Immunodeficiency Virus/metabolism ; Host-Pathogen Interactions ; Virion/metabolism ; Antiviral Agents

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Skocz do pozycji: 10.

Tytuł:: A Conserved Acidic Residue in the C-Terminal Flexible Loop of HIV-1 Nef Contributes to the Activity of SERINC5 and CD4 Downregulation.
Autorzy:: Firrito C; Department of Cellular, Computational and integrative Biology, University of Trento, 38123 Trento, Italy.
Bertelli C; Department of Cellular, Computational and integrative Biology, University of Trento, 38123 Trento, Italy.
Rosa A; Department of Cellular, Computational and integrative Biology, University of Trento, 38123 Trento, Italy.
Chande A; Department of Cellular, Computational and integrative Biology, University of Trento, 38123 Trento, Italy.
Ananth S; Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
van Dijk H; Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Fackler OT; Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, 69120 Heidelberg, Germany.; German Center for Infection Research (DZIF), 69120 Heidelberg, Germany.
Stoneham C; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, San Diego, CA 92161, USA.
Singh R; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, San Diego, CA 92161, USA.
Guatelli J; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, San Diego, CA 92161, USA.
Pizzato M; Department of Cellular, Computational and integrative Biology, University of Trento, 38123 Trento, Italy.; Pokaż więcej
Źródło:: Viruses [Viruses] 2023 Feb 28; Vol. 15 (3). Date of Electronic Publication: 2023 Feb 28.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: CD4-Positive T-Lymphocytes*/immunology
CD4-Positive T-Lymphocytes*/virology
Membrane Proteins*/metabolism
nef Gene Products, Human Immunodeficiency Virus*/chemistry
HIV-1*/pathogenicity
CD4 Antigens*/metabolism
Humans ; Amino Acid Substitution ; HEK293 Cells ; Jurkat Cells ; Amino Acid Sequence ; Endocytosis ; Clathrin ; HIV Infections ; Down-Regulation

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