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Tytuł:
IL-33-ST2 signaling in fibro-adipogenic progenitors alleviates immobilization-induced muscle atrophy in mice.
Autorzy:
Takahashi Y; Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan.
Yoda M; Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan.
Tsuji O; Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan.
Horiuchi K; Department of Orthopedic Surgery, National Defense Medical College, Namiki 3-2, Tokorozawa, Saitama, 359-8513, Japan.
Watanabe K; Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan. .
Nakamura M; Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan.
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Źródło:
Skeletal muscle [Skelet Muscle] 2024 Apr 01; Vol. 14 (1), pp. 6. Date of Electronic Publication: 2024 Apr 01.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-33*/metabolism
Interleukin-1 Receptor-Like 1 Protein*/genetics
Interleukin-1 Receptor-Like 1 Protein*/metabolism
Humans ; Aged ; Mice ; Animals ; Adipogenesis ; Muscle, Skeletal/metabolism ; Muscular Atrophy/etiology ; Muscular Atrophy/prevention & control ; Muscular Atrophy/metabolism ; Cell Differentiation/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The oral IRAK4 inhibitors zabedosertib and BAY1830839 suppress local and systemic immune responses in a randomized trial in healthy male volunteers.
Autorzy:
Jodl SJ; Bayer AG, Berlin, Germany.
Ten Voorde W; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden University Medical Center, Leiden, The Netherlands.
Klein S; Bayer AG, Berlin, Germany.
Wagenfeld A; Bayer AG, Berlin, Germany.
Zollmann FS; Pharma Consult, Berlin, Germany.
Feldmüller M; Bayer AG, Berlin, Germany.
Klarenbeek NB; Centre for Human Drug Research, Leiden, The Netherlands.
de Bruin DT; Centre for Human Drug Research, Leiden, The Netherlands.
Jansen MAA; Centre for Human Drug Research, Leiden, The Netherlands.
Rissmann R; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden Academic Centre for Drug Research, Leiden, The Netherlands.
Rohde B; Bayer AG, Berlin, Germany.
Moerland M; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden University Medical Center, Leiden, The Netherlands.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13771.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Interleukin-1 Receptor-Associated Kinases*
Lipopolysaccharides*
Indazoles*
Pyridines*
Humans ; Male ; Erythema ; Prednisolone ; Imiquimod ; Immunity ; Volunteers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
ISGF3 and STAT2/IRF9 Control Basal and IFN-Induced Transcription through Genome-Wide Binding of Phosphorylated and Unphosphorylated Complexes to Common ISRE-Containing ISGs.
Autorzy:
Nowicka H; Human Molecular Genetics Research Unit, Faculty of Biology, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, 61-614 Poznan, Poland.
Sekrecka A; Human Molecular Genetics Research Unit, Faculty of Biology, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, 61-614 Poznan, Poland.
Blaszczyk K; Human Molecular Genetics Research Unit, Faculty of Biology, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, 61-614 Poznan, Poland.
Kluzek K; Human Molecular Genetics Research Unit, Faculty of Biology, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, 61-614 Poznan, Poland.
Chang CY; Graduate Institute of Immunology, National Taiwan University College of Medicine, Taipei 100, Taiwan.
Wesoly J; Laboratory of High Throughput Technologies, Faculty of Biology, Adam Mickiewicz University, 61-614 Poznan, Poland.
Lee CK; Graduate Institute of Immunology, National Taiwan University College of Medicine, Taipei 100, Taiwan.
Bluyssen HAR; Human Molecular Genetics Research Unit, Faculty of Biology, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, 61-614 Poznan, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 18; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 18.
Typ publikacji:
Journal Article
MeSH Terms:
Interferon Type I*/metabolism
Interleukin-1 Receptor-Like 1 Protein*/metabolism
Interferon-Stimulated Gene Factor 3*/metabolism
STAT2 Transcription Factor*/metabolism
Antiviral Agents/pharmacology ; DNA/pharmacology ; Immunoglobulins/metabolism ; Signal Transduction ; STAT1 Transcription Factor/metabolism ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synergism between IL-33 and MRGPRX2/FcεRI Is Primarily Due to the Complementation of Signaling Modules, and Only Modestly Supplemented by Prolonged Activation of Selected Kinases.
Autorzy:
Franke K; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology IA, 12203 Berlin, Germany.; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.
Li Z; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology IA, 12203 Berlin, Germany.; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.
Bal G; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology IA, 12203 Berlin, Germany.; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.
Zuberbier T; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology IA, 12203 Berlin, Germany.; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.
Babina M; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology IA, 12203 Berlin, Germany.; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.
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Źródło:
Cells [Cells] 2023 Nov 24; Vol. 12 (23). Date of Electronic Publication: 2023 Nov 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
NF-kappa B*/metabolism
Interleukin-1 Receptor-Like 1 Protein*
Humans ; Interleukin-33 ; Signal Transduction ; Phosphatidylinositol 3-Kinases/metabolism ; Nerve Tissue Proteins/metabolism ; Receptors, Neuropeptide/metabolism ; Receptors, G-Protein-Coupled/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mutations in the Vicinity of the IRAK3 Guanylate Cyclase Center Impact Its Subcellular Localization and Ability to Modulate Inflammatory Signaling in Immortalized Cell Lines.
Autorzy:
Turek I; Department of Rural Clinical Sciences, La Trobe Rural Health School, La Trobe University, Bendigo, VIC 3552, Australia.; La Trobe Institute for Molecular Science, La Trobe University, Bendigo, VIC 3552, Australia.
Nguyen TH; Department of Rural Clinical Sciences, La Trobe Rural Health School, La Trobe University, Bendigo, VIC 3552, Australia.; La Trobe Institute for Molecular Science, La Trobe University, Bendigo, VIC 3552, Australia.
Galea C; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, VIC 3052, Australia.
Abad I; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, VIC 3052, Australia.
Freihat L; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, VIC 3052, Australia.
Manallack DT; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, VIC 3052, Australia.
Velkov T; Department of Microbiology, Monash University, Wellington Rd, Clayton, VIC 3800, Australia.
Irving H; Department of Rural Clinical Sciences, La Trobe Rural Health School, La Trobe University, Bendigo, VIC 3552, Australia.; La Trobe Institute for Molecular Science, La Trobe University, Bendigo, VIC 3552, Australia.; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, VIC 3052, Australia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 10; Vol. 24 (10). Date of Electronic Publication: 2023 May 10.
Typ publikacji:
Journal Article
MeSH Terms:
Guanylate Cyclase*/metabolism
Interleukin-1 Receptor-Associated Kinases*/genetics
Interleukin-1 Receptor-Associated Kinases*/metabolism
Humans ; Lipopolysaccharides/pharmacology ; HEK293 Cells ; Mutation ; NF-kappa B/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Different Gene Expression Patterns of IL-1 Family Members in Parkinson's Disease: Results from Bayesian Regression Model.
Autorzy:
Jafariaghdam N; Department of Immunology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. .
Khoshmirsafa M; Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. .
Zamani A; Department of Immunology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. a_.
Talebi-Ghane E; Modeling of noncommunicable Diseases Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. .
Moradi S; Dept of Immunology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. .
Shahba F; Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. .
Mazdeh M; Department of Neurology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. .
Eftekharian MM; Department of Immunology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran AND Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. .
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Źródło:
Iranian journal of allergy, asthma, and immunology [Iran J Allergy Asthma Immunol] 2024 Feb 11; Vol. 23 (1), pp. 69-81. Date of Electronic Publication: 2024 Feb 11.
Typ publikacji:
Journal Article
MeSH Terms:
Parkinson Disease*/genetics
Humans ; Male ; Female ; Interleukin-1 Receptor Accessory Protein/genetics ; Interleukin-1 Receptor Accessory Protein/metabolism ; Case-Control Studies ; Bayes Theorem ; Interleukin-33 ; Interleukin-1beta/genetics ; Gene Expression
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The association of serum IL-33/ST2 expression with hepatocellular carcinoma.
Autorzy:
Pan X; Department of Clinical Laboratory, Guangxi Medical University Cancer Hospital, Nanning, 530021, Guangxi, China.
Liu J; Department of Clinical Laboratory, Guangxi Medical University Cancer Hospital, Nanning, 530021, Guangxi, China.
Li M; Department of Clinical Laboratory, Guangxi Medical University Cancer Hospital, Nanning, 530021, Guangxi, China.
Liang Y; Department of Clinical Laboratory, Guangxi Medical University Cancer Hospital, Nanning, 530021, Guangxi, China.
Liu Z; Department of Clinical Laboratory, Guangxi Medical University Cancer Hospital, Nanning, 530021, Guangxi, China.
Lao M; Department of Clinical Laboratory, Guangxi Medical University Cancer Hospital, Nanning, 530021, Guangxi, China. .
Fang M; Department of Clinical Laboratory, Guangxi Medical University Cancer Hospital, Nanning, 530021, Guangxi, China. .
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Źródło:
BMC cancer [BMC Cancer] 2023 Jul 28; Vol. 23 (1), pp. 704. Date of Electronic Publication: 2023 Jul 28.
Typ publikacji:
Meta-Analysis; Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/pathology
Interleukin-1 Receptor-Like 1 Protein*/genetics
Interleukin-33*/genetics
Liver Neoplasms*/genetics
Liver Neoplasms*/pathology
Humans ; Biomarkers, Tumor/genetics ; Prognosis ; RNA, Messenger/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction.
Autorzy:
England E; Biologics Engineering, R&D, AstraZeneca, Cambridge, UK.
Rees DG; Biologics Engineering, R&D, AstraZeneca, Cambridge, UK.
Scott IC; Translational Science and Experimental Medicine, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Carmen S; Biologics Engineering, R&D, AstraZeneca, Cambridge, UK.
Chan DTY; Biologics Engineering, R&D, AstraZeneca, Cambridge, UK.
Chaillan Huntington CE; Biologics Engineering, R&D, AstraZeneca, Cambridge, UK.
Houslay KF; Bioscience Asthma and Skin Immunity, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Erngren T; Drug Metabolism and Pharmacokinetics, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Penney M; Early Oncology DMPK, Oncology R&D, AstraZeneca, Cambridge, UK.
Majithiya JB; Bioscience Asthma and Skin Immunity, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Rapley L; Bioscience Asthma and Skin Immunity, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Sims DA; Bioscience Asthma and Skin Immunity, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.
Hollins C; Bioscience Asthma and Skin Immunity, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Hinchy EC; Bioscience Asthma and Skin Immunity, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Strain MD; Biologics Engineering, R&D, AstraZeneca, Cambridge, UK.
Kemp BP; Biologics Engineering, R&D, AstraZeneca, Cambridge, UK.
Corkill DJ; Bioscience In Vivo, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
May RD; Bioscience Asthma and Skin Immunity, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Vousden KA; Biologics Engineering, R&D, AstraZeneca, Cambridge, UK.
Butler RJ; Biologics Engineering, R&D, AstraZeneca, Cambridge, UK.
Mustelin T; Division of Rheumatology, Department of Medicine, University of Washington, Seattle, WA, USA.
Vaughan TJ; Biologics Engineering, R&D, AstraZeneca, Cambridge, UK.
Lowe DC; Biologics Engineering, R&D, AstraZeneca, Cambridge, UK.
Colley C; Biologics Engineering, R&D, AstraZeneca, Cambridge, UK.
Cohen ES; Bioscience Asthma and Skin Immunity, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jun 17; Vol. 13 (1), pp. 9825. Date of Electronic Publication: 2023 Jun 17.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-1 Receptor-Like 1 Protein*/metabolism
Inflammation*/metabolism
Mice ; Humans ; Animals ; Interleukin-33/metabolism ; Cytokines/metabolism ; ErbB Receptors/metabolism ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
IRAK-M has effects in regulation of lung epithelial inflammation.
Autorzy:
Li J; Department of Pulmonary and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, #1 Shuaifuyuan, Dongcheng District, Beijing, 100730, China.
Zheng Z; Department of Pulmonary and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, #1 Shuaifuyuan, Dongcheng District, Beijing, 100730, China.
Liu Y; Department of Respiratory Medicine, Civil Aviation General Hospital, Beijing, 100123, China.
Zhang H; Department of Physiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
Zhang Y; Section of Genomic and Environmental Medicine National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK.
Gao J; Department of Pulmonary and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, #1 Shuaifuyuan, Dongcheng District, Beijing, 100730, China. .
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Źródło:
Respiratory research [Respir Res] 2023 Apr 07; Vol. 24 (1), pp. 103. Date of Electronic Publication: 2023 Apr 07.
Typ publikacji:
Journal Article
MeSH Terms:
Asthma*/metabolism
Interleukin-1 Receptor-Associated Kinases*/genetics
Interleukin-1 Receptor-Associated Kinases*/metabolism
Pneumonia*/genetics
Pneumonia*/metabolism
Humans ; Inflammation/genetics ; Inflammation/metabolism ; Lung/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
IL-33/ST2 antagonizes STING signal transduction via autophagy in response to acetaminophen-mediated toxicological immunity.
Autorzy:
Wang Z; Department of Hepatobiliary Surgery and Fujian Institute of Hepatobiliary Surgery, Cancer Center of Fujian Medical University, Fujian Medical University Union Hospital, Fuzhou, China.
Sun P; College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Pan B; Department of Hepatobiliary Surgery and Fujian Institute of Hepatobiliary Surgery, Cancer Center of Fujian Medical University, Fujian Medical University Union Hospital, Fuzhou, China.
Qiu J; Department of Hepatobiliary Surgery and Fujian Institute of Hepatobiliary Surgery, Cancer Center of Fujian Medical University, Fujian Medical University Union Hospital, Fuzhou, China.
Zhang X; Department of Hepatobiliary Surgery and Fujian Institute of Hepatobiliary Surgery, Cancer Center of Fujian Medical University, Fujian Medical University Union Hospital, Fuzhou, China.
Shen S; Department of Hepatobiliary Surgery and Fujian Institute of Hepatobiliary Surgery, Cancer Center of Fujian Medical University, Fujian Medical University Union Hospital, Fuzhou, China.
Ke X; Department of Hepatobiliary Surgery and Fujian Institute of Hepatobiliary Surgery, Cancer Center of Fujian Medical University, Fujian Medical University Union Hospital, Fuzhou, China.
Tang N; Department of Hepatobiliary Surgery and Fujian Institute of Hepatobiliary Surgery, Cancer Center of Fujian Medical University, Fujian Medical University Union Hospital, Fuzhou, China. .; Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Research Center for Molecular Medicine, Fujian Medical University, Fuzhou, China. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2023 Apr 20; Vol. 21 (1), pp. 80. Date of Electronic Publication: 2023 Apr 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms:
Acetaminophen*/adverse effects
Interleukin-1 Receptor-Like 1 Protein*
Animals ; Mice ; Autophagy ; Beclin-1 ; Immunity, Innate/genetics ; Interleukin-33 ; Mice, Inbred C57BL ; Nucleotidyltransferases/metabolism ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Single nucleotide variants in the IL33 and IL1RL1 (ST2) genes are associated with periodontitis and with Aggregatibacter actinomycetemcomitans in the dental plaque biofilm: A putative role in understanding the host immune response in periodontitis.
Autorzy:
Trindade SC; Postgraduate Program in Immunology, Federal University of Bahia, Salvador, Bahia, Brazil.; Department of Health, Feira de Santana State University, Feira de Santana, Bahia, Brazil.
Lopes MPP; Postgraduate Program in Immunology, Federal University of Bahia, Salvador, Bahia, Brazil.
Oliveira TTMC; Postgraduate Program in Immunology, Federal University of Bahia, Salvador, Bahia, Brazil.
Silva MJ; Postgraduate Program in Immunology, Federal University of Bahia, Salvador, Bahia, Brazil.
Queiroz GA; Postgraduate Program in Immunology, Federal University of Bahia, Salvador, Bahia, Brazil.
Jesus TS; Postgraduate Program in Immunology, Federal University of Bahia, Salvador, Bahia, Brazil.
Santos EKN; Postgraduate Program in Immunology, Federal University of Bahia, Salvador, Bahia, Brazil.
Carvalho-Filho PC; Postgraduate Program in Immunology, Federal University of Bahia, Salvador, Bahia, Brazil.
Falcão MML; Postgraduate Program in Immunology, Federal University of Bahia, Salvador, Bahia, Brazil.
Miranda PM; Postgraduate Program in Immunology, Federal University of Bahia, Salvador, Bahia, Brazil.
Santos RPB; Postgraduate Program in Immunology, Federal University of Bahia, Salvador, Bahia, Brazil.
Figueiredo CA; Postgraduate Program in Immunology, Federal University of Bahia, Salvador, Bahia, Brazil.
Cruz ÁA; Postgraduate Program in Health Sciences, Federal University of Bahia, Salvador, Bahia, Brazil.
Seymour GJ; Oral Health Centre, The University of Queensland, Herston, Queensland, Australia.
Gomes-Filho IS; Department of Health, Feira de Santana State University, Feira de Santana, Bahia, Brazil.
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Źródło:
PloS one [PLoS One] 2023 Mar 22; Vol. 18 (3), pp. e0283179. Date of Electronic Publication: 2023 Mar 22 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dental Plaque*/genetics
Interleukin-1 Receptor-Like 1 Protein*/genetics
Interleukin-33*/genetics
Periodontitis*/genetics
Humans ; Aggregatibacter actinomycetemcomitans/genetics ; Biofilms ; Cross-Sectional Studies ; Immunity ; Nucleotides ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibition of IRAK1 Is an Effective Therapy for Autoimmune Hypophysitis in Mice.
Autorzy:
Huang HC; Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.
Chen YT; Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.
Lin HH; Institute of Molecular Medicine and Bioengineering, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.
Li ZQ; Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.
Yang JM; Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.; Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.; Center for Intelligent Drug Systems and Smart Bio-Devices, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.
Tzou SC; Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.; Institute of Molecular Medicine and Bioengineering, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.; Center for Intelligent Drug Systems and Smart Bio-Devices, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 29; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 29.
Typ publikacji:
Journal Article
MeSH Terms:
Autoimmune Hypophysitis*/therapy
Interleukin-1 Receptor-Associated Kinases*/antagonists & inhibitors
Autoantigens ; Animals ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Potassium humate and cobalt enhance peanut tolerance to water stress through regulation of proline, antioxidants, and maintenance of nutrient homeostasis.
Autorzy:
Elshamly AMS; Water Studies and Research Complex, National Water Research Centre, Cairo, Egypt. ayman_.
Parrey ZA; Plant Physiology and Biochemistry Section, Department of Botany, Aligarh Muslim University, Aligarh, 202002, India.
Gaafar AZ; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Siddiqui MH; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Hussain S; College of Agronomy, Key Laboratory of Crop Physio-Ecology and Tillage in Northwestern Loess Plateau, Ministry of Agriculture, Northwest A&F University, Yangling, Shaanxi, China.
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 18; Vol. 14 (1), pp. 1625. Date of Electronic Publication: 2024 Jan 18.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*/metabolism
Arachis*/metabolism
Potassium/metabolism ; Dehydration ; Cobalt ; Proline/metabolism ; Interleukin-1 Receptor-Like 1 Protein ; Minerals ; Chlorophyll/metabolism ; Homeostasis ; Nutrients
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Role of IL-33-ST2 pathway in regulating inflammation: current evidence and future perspectives.
Autorzy:
Zhou Y; Department of Anesthesiology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Xu Z; Department of Anesthesiology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China. .
Liu Z; Department of Anesthesiology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2023 Dec 11; Vol. 21 (1), pp. 902. Date of Electronic Publication: 2023 Dec 11.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Lung Diseases*
Sepsis*
Pulmonary Disease, Chronic Obstructive*
Humans ; Interleukin-33 ; Interleukin-1 Receptor-Like 1 Protein/metabolism ; Endothelial Cells/metabolism ; Inflammation/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Oligodendrocyte-derived IL-33 functions as a microglial survival factor during neuroinvasive flavivirus infection.
Autorzy:
Norris GT; Department of Immunology, University of Washington, Seattle Washington, United States of America.
Ames JM; Department of Immunology, University of Washington, Seattle Washington, United States of America.
Ziegler SF; Department of Immunology, University of Washington, Seattle Washington, United States of America.; Center for Fundamental Immunology, Benaroya Research Institute, Seattle Washington, United States of America.
Oberst A; Department of Immunology, University of Washington, Seattle Washington, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 Nov 20; Vol. 19 (11), pp. e1011350. Date of Electronic Publication: 2023 Nov 20 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Flavivirus Infections*/metabolism
Interleukin-33*/metabolism
Microglia*/metabolism
Humans ; Central Nervous System ; Interleukin-1 Receptor-Like 1 Protein/metabolism ; Animals ; Mice
Czasopismo naukowe
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Tytuł:
Comparative genotypic characterization related to antibiotic resistance phenotypes of clinical carbapenem-resistant Acinetobacter baumannii MTC1106 (ST2) and MTC0619 (ST25).
Autorzy:
Wiradiputra MRD; Antimicrobial Resistance Interdisciplinary Group (AmRIG), Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.; Biopharmaceutical Sciences Program, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Thirapanmethee K; Antimicrobial Resistance Interdisciplinary Group (AmRIG), Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.; Department of Microbiology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Khuntayaporn P; Antimicrobial Resistance Interdisciplinary Group (AmRIG), Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.; Department of Microbiology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Wanapaisan P; Antimicrobial Resistance Interdisciplinary Group (AmRIG), Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.; Department of Microbiology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Chomnawang MT; Antimicrobial Resistance Interdisciplinary Group (AmRIG), Faculty of Pharmacy, Mahidol University, Bangkok, Thailand. .; Department of Microbiology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand. .
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Źródło:
BMC genomics [BMC Genomics] 2023 Nov 17; Vol. 24 (1), pp. 689. Date of Electronic Publication: 2023 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Colistin*/pharmacology
Acinetobacter baumannii*/genetics
Interleukin-1 Receptor-Like 1 Protein/genetics ; RNA, Ribosomal, 16S ; Microbial Sensitivity Tests ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Anti-Bacterial Agents/pharmacology ; beta-Lactamases/genetics ; Carbapenems/pharmacology ; Aminoglycosides/pharmacology ; Drug Resistance, Multiple, Bacterial/genetics ; Phenotype
Czasopismo naukowe
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Tytuł:
Soluble suppression of tumorigenicity 2 is a potential predictor of post-liver transplant renal outcomes.
Autorzy:
Moon JJ; Seoul National University Biomedical Research Institute, Seoul, Korea.
Hong SK; Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Kim YC; Division of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Hong SY; Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Choi Y; Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Yi NJ; Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Lee KW; Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Han SS; Division of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Lee H; Division of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Kim DK; Division of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.; Kidney Research Institute, Seoul National University Medical Research Center, Seoul, Korea.
Kim YS; Division of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.; Kidney Research Institute, Seoul National University Medical Research Center, Seoul, Korea.
Yang SH; Seoul National University Biomedical Research Institute, Seoul, Korea.; Kidney Research Institute, Seoul National University Medical Research Center, Seoul, Korea.
Suh KS; Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
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Źródło:
PloS one [PLoS One] 2023 Nov 02; Vol. 18 (11), pp. e0293844. Date of Electronic Publication: 2023 Nov 02 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
End Stage Liver Disease*
Hepatorenal Syndrome*
Liver Transplantation*/adverse effects
Acute Kidney Injury*/etiology
Humans ; Severity of Illness Index ; Kidney ; Interleukin-1 Receptor-Like 1 Protein ; Biomarkers
Czasopismo naukowe
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Tytuł:
IRAK3 Knockout and Wildtype THP-1 Monocytes as Models for Endotoxin Detection Assays and Fusobacterium nucleatum Bacteriophage FNU1 Cytokine Induction.
Autorzy:
Binte Mohamed Yakob Adil SS; Department of Rural Clinical Sciences, La Trobe Rural Health School, La Trobe University, P.O. Box 199, Bendigo, VIC 3550, Australia.; La Trobe Institute for Molecular Science, La Trobe University, P.O. Box 199, Bendigo, VIC 3550, Australia.
Kabwe M; Department of Rural Clinical Sciences, La Trobe Rural Health School, La Trobe University, P.O. Box 199, Bendigo, VIC 3550, Australia.; La Trobe Institute for Molecular Science, La Trobe University, P.O. Box 199, Bendigo, VIC 3550, Australia.
Cianciarulo C; Department of Rural Clinical Sciences, La Trobe Rural Health School, La Trobe University, P.O. Box 199, Bendigo, VIC 3550, Australia.; La Trobe Institute for Molecular Science, La Trobe University, P.O. Box 199, Bendigo, VIC 3550, Australia.
Nguyen TH; Department of Rural Clinical Sciences, La Trobe Rural Health School, La Trobe University, P.O. Box 199, Bendigo, VIC 3550, Australia.
Irving H; Department of Rural Clinical Sciences, La Trobe Rural Health School, La Trobe University, P.O. Box 199, Bendigo, VIC 3550, Australia.; La Trobe Institute for Molecular Science, La Trobe University, P.O. Box 199, Bendigo, VIC 3550, Australia.
Tucci J; Department of Rural Clinical Sciences, La Trobe Rural Health School, La Trobe University, P.O. Box 199, Bendigo, VIC 3550, Australia.; La Trobe Institute for Molecular Science, La Trobe University, P.O. Box 199, Bendigo, VIC 3550, Australia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 12; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Journal Article
MeSH Terms:
Cytokines*/metabolism
Bacteriophages*/genetics
Bacteriophages*/metabolism
Humans ; Monocytes/metabolism ; Fusobacterium nucleatum/metabolism ; Endotoxins/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Anti-Bacterial Agents/metabolism ; Interleukin-1 Receptor-Associated Kinases/genetics ; Interleukin-1 Receptor-Associated Kinases/metabolism
Czasopismo naukowe
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Tytuł:
IL-33/ST2 Activation Is involved in Ro60-Regulated Photosensitivity in Cutaneous Lupus Erythematosus.
Autorzy:
Song Y; Department of Internal Medicine of Traditional Chinese Medicine, Hainan Medical University, Haikou, 571199 Hainan, China.
Wei F; Department of Internal Medicine of Traditional Chinese Medicine, Hainan Medical University, Haikou, 571199 Hainan, China.
Liu Y; Department of Rheumatology and Immunology, Hainan General Hospital, Haikou, 570311 Hainan, China.
Han F; Department of Laboratory Medicine, The First Affiliated Hospital of Hainan Medical College, Haikou, 570102 Hainan, China.
Ma L; Department of Rheumatology and Immunology, The First Affiliated Hospital of Hainan Medical College, Haikou, 570102 Hainan, China.
Zhuang Y; Department of Internal Medicine of Traditional Chinese Medicine, Hainan Medical University, Haikou, 571199 Hainan, China.
Pan C; Department of Internal Medicine of Traditional Chinese Medicine, Hainan Medical University, Haikou, 571199 Hainan, China.
Jia Z; Department of Nephrology, Ningbo Hospital of Traditional Chinese Medicine, Affiliated to Zhejiang Chinese Medical University, Ningbo, 315000 Zhejiang, China.
Gong A; Department of Internal Medicine of Traditional Chinese Medicine, Hainan Medical University, Haikou, 571199 Hainan, China.
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Źródło:
Mediators of inflammation [Mediators Inflamm] 2022 Jul 20; Vol. 2022, pp. 4955761. Date of Electronic Publication: 2022 Jul 20 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-1 Receptor-Like 1 Protein*/genetics
Interleukin-1 Receptor-Like 1 Protein*/metabolism
Interleukin-33*/genetics
Interleukin-33*/metabolism
Lupus Erythematosus, Cutaneous*/complications
Lupus Erythematosus, Cutaneous*/genetics
Lupus Erythematosus, Cutaneous*/metabolism
Animals ; Autoantigens/genetics ; Autoantigens/metabolism ; Humans ; Inflammation/genetics ; Inflammation/metabolism ; Keratinocytes/metabolism ; Mice ; NF-kappa B/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Photosensitivity Disorders/etiology ; Photosensitivity Disorders/genetics ; Photosensitivity Disorders/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Small Cytoplasmic/genetics ; RNA, Small Cytoplasmic/metabolism ; Ribonucleoproteins/genetics ; Ribonucleoproteins/metabolism ; SOXF Transcription Factors/metabolism ; Ultraviolet Rays/adverse effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Increased expression of IL1-RL1 is associated with type 2 and type 1 immune pathways in asthma.
Autorzy:
Xu C; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.
Du L; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.
Chen F; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.
Tang K; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.
Tang L; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.
Shi J; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.
Xiao L; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.
Zeng Z; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China. .; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China. .
Liang Y; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China. .; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China. .
Guo Y; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China. .; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China. .
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Źródło:
BMC immunology [BMC Immunol] 2022 May 16; Vol. 23 (1), pp. 23. Date of Electronic Publication: 2022 May 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Asthma*/immunology
Interleukin-1 Receptor-Like 1 Protein*/biosynthesis
Interleukin-1 Receptor-Like 1 Protein*/immunology
Biomarkers/metabolism ; Cytokines/metabolism ; Eosinophils ; Humans ; Immunoglobulin E/immunology ; Interleukins/immunology ; Nitric Oxide/immunology
Czasopismo naukowe
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